BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
173736	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor		 0.15								PDSP Ki		10.7270/Q2N0152V	9023329			Maguire, JJ; Kuc, RE; Davenport, AP	University of Cambridge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
173737	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor		 0.5								PDSP Ki		10.7270/Q2N0152V	9023329			Maguire, JJ; Kuc, RE; Davenport, AP	University of Cambridge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
173738	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor		 0.92								PDSP Ki		10.7270/Q2N0152V	9023329			Maguire, JJ; Kuc, RE; Davenport, AP	University of Cambridge	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
175748	Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2[C@@]3(C)CCC(C3)C2(C)C)cc1	InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22?,27?,29-/m0/s1	SUGVYNSRNKFXQM-ACSDJOOWSA-N	21280	5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl]-1H-pyrazole-3-carboxamide::N-(1,3,3-trimethylbicyclo(2.2.1)heptan-2-yl)-5-(4-chloro-3-methylphenyl)-1-(4-methylbenzyl)pyrazole-3-carboxamide::SR 144528::SR-144528::SR144528	Endothelin-1 receptor		>10000								PDSP Ki		10.7270/Q2D50KHT	9454810			Rinaldi-Carmona, M; Barth, F; Millan, J; Derocq, JM; Casellas, P; Congy, C; Oustric, D; Sarran, M; Bouaboula, M; Calandra, B; Portier, M; Shire, D; Breliere, JC; Le Fur, GL	Sanofi Recherche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21280&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21310426	49689352						ZINC03952700	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
178692	CCCCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1C[C@H](C)C(O)=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C31H33NO7/c1-4-5-6-20-8-10-23-26(18-7-12-24-25(15-18)39-16-38-24)28(31(35)36)27(29(23)32-20)22-11-9-21(37-3)14-19(22)13-17(2)30(33)34/h7-12,14-15,17,26-28H,4-6,13,16H2,1-3H3,(H,33,34)(H,35,36)/t17-,26-,27-,28+/m0/s1	IUHMIOAKWHUFKU-YINIXLNUSA-N	50143784	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((S)-2-carboxy-propyl)-4-methoxy-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL305576::J-104132	Endothelin-1 receptor		 0.03								PDSP Ki		10.7270/Q2Q52N5Q	10336515			Nishikibe, M; Ohta, H; Okada, M; Ishikawa, K; Hayama, T; Fukuroda, T; Noguchi, K; Saito, M; Kanoh, T; Ozaki, S; Kamei, T; Hara, K; William, D; Kivlighn, S; Krause, S; Gabel, R; Zingaro, G; Nolan, N; O'Brien, J; Clayton, F; Lynch, J; Pettibone, D; Siegl, P	Banyu Pharmaceutical Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143784&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			186002	104032944		CHEMBL305576				ZINC29570059	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
177834	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-3-10-35-18-6-7-19-21(12-18)27(20-8-5-17(34-2)13-23(20)36-14-25(30)31)28(29(32)33)26(19)16-4-9-22-24(11-16)38-15-37-22/h4-9,11-13,26-28H,3,10,14-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27+,28+/m0/s1	UUAVCCWBNUITBB-UPRLRBBYSA-N	50041617	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid::1-benzo[d][1,3]dioxol-5-ylmethyl-3-(2-carboxymethoxy-4-methoxyphenyl)-5-propoxy-(1R,3S)-2,3-dihydro-1H-2-indenecarboxylic acid::CHEMBL8823::SB 209670::SB-209670	Endothelin-1 receptor		 0.4								PDSP Ki		10.7270/Q2V40SSK	9694916			Ohlstein, EH; Nambi, P; Hay, DW; Gellai, M; Brooks, DP; Luengo, J; Xiang, JN; Elliott, JD	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			108002	103973307		CHEMBL8823		3528		ZINC01536124	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
177835	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCCO)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H30O8/c1-3-11-34-19-6-7-20-22(14-19)27(21-8-5-18(33-2)15-24(21)35-12-10-30)28(29(31)32)26(20)17-4-9-23-25(13-17)37-16-36-23/h4-9,13-15,26-28,30H,3,10-12,16H2,1-2H3,(H,31,32)/t26-,27+,28+/m0/s1	GLCKXJLCYIJMRB-UPRLRBBYSA-N	50061077	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy-ethoxy)-4-methoxy-phenyl]-5-propoxy-indan-2-carboxylic acid::CHEMBL431651::Enrasentan::SB 217242::SB-217242	Endothelin-1 receptor		 1.5								PDSP Ki		10.7270/Q2V40SSK	9694916			Ohlstein, EH; Nambi, P; Hay, DW; Gellai, M; Brooks, DP; Luengo, J; Xiang, JN; Elliott, JD	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061077&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			178103	103956664		CHEMBL431651				ZINC03825437	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
177836	CCCCn1ncc(\C=C(/Cc2cc3OCOc3cc2OC)C(O)=O)c1-c1ccc(OC)cc1OCc1ccccc1C(O)=O	InChI=1S/C34H34N2O9/c1-4-5-12-36-32(27-11-10-25(41-2)16-29(27)43-19-21-8-6-7-9-26(21)34(39)40)24(18-35-36)14-23(33(37)38)13-22-15-30-31(45-20-44-30)17-28(22)42-3/h6-11,14-18H,4-5,12-13,19-20H2,1-3H3,(H,37,38)(H,39,40)/b23-14+	MCHCGWZNXSZKJY-OEAKJJBVSA-N	85335	SB 234551::SB-234551	Endothelin-1 receptor		 0.13								PDSP Ki		10.7270/Q2V40SSK	9694916			Ohlstein, EH; Nambi, P; Hay, DW; Gellai, M; Brooks, DP; Luengo, J; Xiang, JN; Elliott, JD	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85335&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5311425	136351435				1000		ZINC40772053	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
188898	ONC=Nc1ccc(N2CCOCC2)c(Cl)c1	InChI=1S/C11H14ClN3O2/c12-10-7-9(13-8-14-16)1-2-11(10)15-3-5-17-6-4-15/h1-2,7-8,16H,3-6H2,(H,13,14)	ZTXADXBIGLLOFX-UHFFFAOYSA-N	86694	N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyformamidine::TS-011	Endothelin-1 receptor		>10000								PDSP Ki	10.1124/jpet.105.083964	10.7270/Q2MW2FQQ	15831442			Miyata, N; Seki, T; Tanaka, Y; Omura, T; Taniguchi, K; Doi, M; Bandou, K; Kametani, S; Sato, M; Okuyama, S; Cambj-Sapunar, L; Harder, DR; Roman, RJ	Taisho Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86694&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9816527	136352743						ZINC06746071	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
188011	CCc1c(nn(c1-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1	InChI=1S/C23H23BrCl2N4O/c1-2-18-21(23(31)28-29-12-4-3-5-13-29)27-30(20-11-10-17(25)14-19(20)26)22(18)15-6-8-16(24)9-7-15/h6-11,14H,2-5,12-13H2,1H3,(H,28,31)	HMXDWDSNPRNUKI-UHFFFAOYSA-N	50171290	5-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide::CHEMBL189676::SR 147778	Endothelin-1 receptor		 1000								PDSP Ki	10.1124/jpet.104.067884	10.7270/Q2RR1WTX	15131245			Rinaldi-Carmona, M; Barth, F; Congy, C; Martinez, S; Oustric, D; Pério, A; Poncelet, M; Maruani, J; Arnone, M; Finance, O; Soubrié, P; Le Fur, G	Sanofi-Synthelabo Recherche	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171290&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9849616	104057543		CHEMBL189676				ZINC01549068	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50002122	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H60N8O10/c1-6-24(3)36(41(58)49-34(43(60)61)21-28-23-45-30-17-12-11-16-29(28)30)51-42(59)37(25(4)7-2)50-40(57)33(22-35(53)54)48-38(55)31(18-13-19-44)47-39(56)32(46-26(5)52)20-27-14-9-8-10-15-27/h8-12,14-17,23-25,31-34,36-37,45H,6-7,13,18-22,44H2,1-5H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t24-,25-,31-,32+,33-,34-,36-,37-/m0/s1	WXVKATPLQWNUHO-POYKSISPSA-N	50045227	(S)-3-[2-((R)-2-Acetylamino-3-phenyl-propionylamino)-5-amino-pentanoylamino]-N-{(S)-1-[(S)-1-((S)-carboxy-2-(S)-1-1H-indol-3-yl-ethylcarbamoyl)-2-(S)-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Orn-Asp-Ile-Ile-Trp::CHEMBL2370070	Endothelin-1 receptor			 750							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045227&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73356095	103976318		CHEMBL2370070				ZINC95610422	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50002125	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33+,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-YNIJNJSISA-N	50001217	3-[2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL86814	Endothelin-1 receptor			>10000							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001217&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297023	103915682		CHEMBL86814				ZINC95610946	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006020	O=CC(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H15NO3/c24-12-17(14-9-10-20-21(11-14)26-13-25-20)22-15-5-1-3-7-18(15)23-19-8-4-2-6-16(19)22/h1-12,17H,13H2	QIHJVAFQIZXEHC-UHFFFAOYSA-N	50288543	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetaldehyde::CHEMBL103484	Endothelin-1 receptor			 1500							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288543&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332577	104130114		CHEMBL103484				ZINC26815912	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006036	COC(=O)C(c1ccc(OC)cc1)c1c2ccccc2nc2ccccc12	InChI=1S/C23H19NO3/c1-26-16-13-11-15(12-14-16)21(23(25)27-2)22-17-7-3-5-9-19(17)24-20-10-6-4-8-18(20)22/h3-14,21H,1-2H3	KBQGRULKAIRHCV-UHFFFAOYSA-N	50288544	Acridin-9-yl-(4-methoxy-phenyl)-acetic acid methyl ester::CHEMBL316650	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288544&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332361	104130115		CHEMBL316650				ZINC26816024	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50007473	COc1ccc(cc1)C(=O)C(\Cc1ccccc1)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-29-19-10-7-17(8-11-19)24(26)20(13-16-5-3-2-4-6-16)23(25(27)28)18-9-12-21-22(14-18)31-15-30-21/h2-12,14H,13,15H2,1H3,(H,27,28)/p-1/b23-20-	VJWJTNIBNOJJIE-ATJXCDBQSA-M	50057155	(Z)-2-Benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate(2-hydroxy-ethyl)-trimethyl-ammonium;::CHEMBL10801::CHEMBL51530	Endothelin-1 receptor			 7.4							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057155&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18792235	103953235		CHEMBL10801CHEMBL51530				ZINC03945731	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005467	CC(C)Oc1c(sc2ccc(OCc3ccccc3)cc12)C(O)=O	InChI=1S/C19H18O4S/c1-12(2)23-17-15-10-14(22-11-13-6-4-3-5-7-13)8-9-16(15)24-18(17)19(20)21/h3-10,12H,11H2,1-2H3,(H,20,21)	MFIHFDWJBWXRFD-UHFFFAOYSA-N	50287187	5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid::CHEMBL10143	Endothelin-1 receptor			 8800							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14673588	104128758		CHEMBL10143				ZINC26004833	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005468	COc1cccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OC)c(OC)cc23)c1	InChI=1S/C26H23NO7S/c1-30-16-5-4-6-17(10-16)35-25-18-11-21(31-2)22(32-3)12-19(18)27(24(25)26(28)29)13-15-7-8-20-23(9-15)34-14-33-20/h4-12H,13-14H2,1-3H3,(H,28,29)	XPUJKHFCHQYTEQ-UHFFFAOYSA-N	50287186	1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL285368	Endothelin-1 receptor			 33							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287186&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15289330	104128757		CHEMBL285368				ZINC28769213	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005471	COc1cc2c(Sc3ccc4OCOc4c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OCc1ccccc1	InChI=1S/C32H25NO8S/c1-36-26-13-22-23(14-29(26)37-16-19-5-3-2-4-6-19)33(15-20-7-9-24-27(11-20)40-17-38-24)30(32(34)35)31(22)42-21-8-10-25-28(12-21)41-18-39-25/h2-14H,15-18H2,1H3,(H,34,35)	DYHGVCADLVCJGZ-UHFFFAOYSA-N	50287197	1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-6-benzyloxy-5-methoxy-1H-indole-2-carboxylic acid::CHEMBL29147	Endothelin-1 receptor			 3400							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287197&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995989	104128768		CHEMBL29147				ZINC28769202	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005472	COc1cc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc4OCOc4cc23)cc(OC)c1OC	InChI=1S/C27H23NO9S/c1-31-22-7-15(8-23(32-2)25(22)33-3)38-26-16-9-20-21(37-13-36-20)10-17(16)28(24(26)27(29)30)11-14-4-5-18-19(6-14)35-12-34-18/h4-10H,11-13H2,1-3H3,(H,29,30)	FDDMPZZHBROSPE-UHFFFAOYSA-N	50287190	5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL28920	Endothelin-1 receptor			 64							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287190&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995991	104128761		CHEMBL28920				ZINC28769104	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005479	COc1ccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc4OCOc4cc23)cc1OC	InChI=1S/C26H21NO8S/c1-30-18-6-4-15(8-20(18)31-2)36-25-16-9-22-23(35-13-34-22)10-17(16)27(24(25)26(28)29)11-14-3-5-19-21(7-14)33-12-32-19/h3-10H,11-13H2,1-2H3,(H,28,29)	QLKHVLXMFAFDAZ-UHFFFAOYSA-N	50287196	5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL28563	Endothelin-1 receptor			 65							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287196&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995992	104128767		CHEMBL28563				ZINC28771073	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005480	COc1cc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OC)c(OC)cc23)cc(OC)c1OC	InChI=1S/C28H27NO9S/c1-32-20-11-17-18(12-21(20)33-2)29(13-15-6-7-19-22(8-15)38-14-37-19)25(28(30)31)27(17)39-16-9-23(34-3)26(36-5)24(10-16)35-4/h6-12H,13-14H2,1-5H3,(H,30,31)	GMNFTSXERCOCMB-UHFFFAOYSA-N	50287200	1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4,5-trimethoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL287169	Endothelin-1 receptor			 4.6							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287200&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9807691	104128771		CHEMBL287169				ZINC01542797	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005475	COc1ccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc4OCOc4cc23)cc1OC	InChI=1S/C26H21NO8S/c1-30-18-6-4-15(8-20(18)31-2)36-25-16-9-22-23(35-13-34-22)10-17(16)27(24(25)26(28)29)11-14-3-5-19-21(7-14)33-12-32-19/h3-10H,11-13H2,1-2H3,(H,28,29)	QLKHVLXMFAFDAZ-UHFFFAOYSA-N	50287196	5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4-dimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL28563	Endothelin-1 receptor			 41							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287196&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995992	104128767		CHEMBL28563				ZINC28771073	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005477	COc1cc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OC)c(OC)cc23)cc(OC)c1OC	InChI=1S/C28H27NO9S/c1-32-20-11-17-18(12-21(20)33-2)29(13-15-6-7-19-22(8-15)38-14-37-19)25(28(30)31)27(17)39-16-9-23(34-3)26(36-5)24(10-16)35-4/h6-12H,13-14H2,1-5H3,(H,30,31)	GMNFTSXERCOCMB-UHFFFAOYSA-N	50287200	1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3,4,5-trimethoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL287169	Endothelin-1 receptor			 2							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287200&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9807691	104128771		CHEMBL287169				ZINC01542797	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005482	COc1cc2c(Sc3ccc4OCOc4c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OCc1ccccc1	InChI=1S/C32H25NO8S/c1-36-26-13-22-23(14-29(26)37-16-19-5-3-2-4-6-19)33(15-20-7-9-24-27(11-20)40-17-38-24)30(32(34)35)31(22)42-21-8-10-25-28(12-21)41-18-39-25/h2-14H,15-18H2,1H3,(H,34,35)	DYHGVCADLVCJGZ-UHFFFAOYSA-N	50287197	1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-6-benzyloxy-5-methoxy-1H-indole-2-carboxylic acid::CHEMBL29147	Endothelin-1 receptor			 620							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287197&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995989	104128768		CHEMBL29147				ZINC28769202	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477427	COc1cc2c(Sc3ccc4OCOc4c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OC	InChI=1S/C26H21NO8S/c1-30-20-9-16-17(10-21(20)31-2)27(11-14-3-5-18-22(7-14)34-12-32-18)24(26(28)29)25(16)36-15-4-6-19-23(8-15)35-13-33-19/h3-10H,11-13H2,1-2H3,(H,28,29)	NQDCDWVUSPOECA-UHFFFAOYSA-N	50287183	1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL27732	Endothelin-1 receptor			 100							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287183&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9957883	104128754		CHEMBL27732				ZINC28769169	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006035	NC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16N2O3/c23-22(25)20(13-9-10-18-19(11-13)27-12-26-18)21-14-5-1-3-7-16(14)24-17-8-4-2-6-15(17)21/h1-11,20H,12H2,(H2,23,25)	WGZNLQUCFSXCGZ-UHFFFAOYSA-N	50288536	2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-acetamide::CHEMBL100120	Endothelin-1 receptor			 7900							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288536&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332624	104130107		CHEMBL100120				ZINC26749862	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006023	COC(=O)C(Cc1c2ccccc2cc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C25H20O4/c1-27-25(26)21(18-10-11-23-24(13-18)29-15-28-23)14-22-19-8-4-2-6-16(19)12-17-7-3-5-9-20(17)22/h2-13,21H,14-15H2,1H3	WORMRQGTWISKMH-UHFFFAOYSA-N	50288534	3-Anthracen-9-yl-2-benzo[1,3]dioxol-5-yl-propionic acid methyl ester::CHEMBL103731	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288534&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332641	104130105		CHEMBL103731				ZINC26818082	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006037	COC(=O)C(c1ccc2OCOc2c1)c1c2CCCCc2nc2ccccc12	InChI=1S/C23H21NO4/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2,4,6,8,10-12,21H,3,5,7,9,13H2,1H3	OQUYJGQEHATGLA-UHFFFAOYSA-N	50288550	Benzo[1,3]dioxol-5-yl-(1,2,3,4-tetrahydro-acridin-9-yl)-acetic acid methyl ester::CHEMBL102494	Endothelin-1 receptor			 11000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288550&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10452089	104130121		CHEMBL102494				ZINC26824012	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006038	Cc1cc(C(C(N)=O)c2ccc3OCOc3c2)c2ccccc2n1	InChI=1S/C19H16N2O3/c1-11-8-14(13-4-2-3-5-15(13)21-11)18(19(20)22)12-6-7-16-17(9-12)24-10-23-16/h2-9,18H,10H2,1H3,(H2,20,22)	HBEHERBGDLPFGC-UHFFFAOYSA-N	50288546	2-Benzo[1,3]dioxol-5-yl-2-(2-methyl-quinolin-4-yl)-acetamide::CHEMBL103886	Endothelin-1 receptor			 37000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288546&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332623	104130117		CHEMBL103886				ZINC26815675	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480056	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C23H17NO4/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	OOTHGTPTLCSOEZ-UHFFFAOYSA-N	50288537	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid methyl ester::CHEMBL320236	Endothelin-1 receptor			 2800							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288537&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9820754	104130108		CHEMBL320236				ZINC13906495	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480057	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C23H17NO4/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	OOTHGTPTLCSOEZ-UHFFFAOYSA-N	50288537	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid methyl ester::CHEMBL320236	Endothelin-1 receptor			 4300							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288537&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9820754	104130108		CHEMBL320236				ZINC13906495	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480061	O=C(OCc1ccccc1)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C29H21NO4/c31-29(32-17-19-8-2-1-3-9-19)27(20-14-15-25-26(16-20)34-18-33-25)28-21-10-4-6-12-23(21)30-24-13-7-5-11-22(24)28/h1-16,27H,17-18H2	HWNMJOYXZVLVOL-UHFFFAOYSA-N	50288557	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid benzyl ester::CHEMBL316792	Endothelin-1 receptor			 7500							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288557&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332807	104130128		CHEMBL316792				ZINC26821977	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480063	COc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1	InChI=1S/C30H23NO5/c1-33-21-13-10-19(11-14-21)17-34-30(32)28(20-12-15-26-27(16-20)36-18-35-26)29-22-6-2-4-8-24(22)31-25-9-5-3-7-23(25)29/h2-16,28H,17-18H2,1H3	XRBYSZSXEPYWSC-UHFFFAOYSA-N	50288541	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-methoxy-benzyl ester::CHEMBL101239	Endothelin-1 receptor			 8200							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288541&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332638	104130112		CHEMBL101239				ZINC26752133	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480066	COC(=O)C(C1c2ccccc2CCc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C25H22O4/c1-27-25(26)23(18-12-13-21-22(14-18)29-15-28-21)24-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)24/h2-9,12-14,23-24H,10-11,15H2,1H3	YRFGKNFBHATPQQ-UHFFFAOYSA-N	50288531	Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-acetic acid methyl ester::CHEMBL103362	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288531&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332777	104130102		CHEMBL103362				ZINC26815859	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480072	CC(C)(C)c1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1	InChI=1S/C33H29NO4/c1-33(2,3)23-15-12-21(13-16-23)19-36-32(35)30(22-14-17-28-29(18-22)38-20-37-28)31-24-8-4-6-10-26(24)34-27-11-7-5-9-25(27)31/h4-18,30H,19-20H2,1-3H3	AMWHTWLJFCHTAT-UHFFFAOYSA-N	50288555	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-tert-butyl-benzyl ester::CHEMBL319679	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288555&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332776	104130126		CHEMBL319679				ZINC26815850	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480074	COC(=O)C(c1ccc(cc1)[N+]([O-])=O)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16N2O4/c1-28-22(25)20(14-10-12-15(13-11-14)24(26)27)21-16-6-2-4-8-18(16)23-19-9-5-3-7-17(19)21/h2-13,20H,1H3	WCIYXANHYASICQ-UHFFFAOYSA-N	50288554	Acridin-9-yl-(4-nitro-phenyl)-acetic acid methyl ester::CHEMBL103573	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288554&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332824	104130125		CHEMBL103573				ZINC26818916	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480075	COC(=O)C(c1ccc2OC(C)(C)Oc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C25H21NO4/c1-25(2)29-20-13-12-15(14-21(20)30-25)22(24(27)28-3)23-16-8-4-6-10-18(16)26-19-11-7-5-9-17(19)23/h4-14,22H,1-3H3	GTLRAUMURPBKNZ-UHFFFAOYSA-N	50288547	Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-acetic acid methyl ester::CHEMBL103572	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288547&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332823	104130118		CHEMBL103572				ZINC26818907	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006866	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 80.0							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005996	COC(=O)C(c1ccc(OC)cc1)c1c2ccccc2nc2ccccc12	InChI=1S/C23H19NO3/c1-26-16-13-11-15(12-14-16)21(23(25)27-2)22-17-7-3-5-9-19(17)24-20-10-6-4-8-18(20)22/h3-14,21H,1-2H3	KBQGRULKAIRHCV-UHFFFAOYSA-N	50288544	Acridin-9-yl-(4-methoxy-phenyl)-acetic acid methyl ester::CHEMBL316650	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288544&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332361	104130115		CHEMBL316650				ZINC26816024	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006002	COC(=O)C(c1ccc(OC)c(OC)c1)c1c2ccccc2nc2ccccc12	InChI=1S/C24H21NO4/c1-27-20-13-12-15(14-21(20)28-2)22(24(26)29-3)23-16-8-4-6-10-18(16)25-19-11-7-5-9-17(19)23/h4-14,22H,1-3H3	WBBHMOSIDJLELA-UHFFFAOYSA-N	50288551	Acridin-9-yl-(3,4-dimethoxy-phenyl)-acetic acid methyl ester::CHEMBL103308	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288551&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21559928	104130122		CHEMBL103308				ZINC26820006	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006005	COC(=O)C(c1ccc(Cl)c(Cl)c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H15Cl2NO2/c1-27-22(26)20(13-10-11-16(23)17(24)12-13)21-14-6-2-4-8-18(14)25-19-9-5-3-7-15(19)21/h2-12,20H,1H3	UEBHINCCWHIGGV-UHFFFAOYSA-N	50288535	Acridin-9-yl-(3,4-dichloro-phenyl)-acetic acid methyl ester::CHEMBL103872	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288535&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332345	104130106		CHEMBL103872				ZINC26819611	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006009	COC(=O)C(Oc1c2ccccc2nc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C23H17NO5/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)29-22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	XVWPMUDIMPSZCK-UHFFFAOYSA-N	50288538	(Acridin-9-yloxy)-benzo[1,3]dioxol-5-yl-acetic acid methyl ester::CHEMBL330414	Endothelin-1 receptor			 4600							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288538&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10385531	104130109		CHEMBL330414				ZINC26753060	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006010	OCC(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H17NO3/c24-12-17(14-9-10-20-21(11-14)26-13-25-20)22-15-5-1-3-7-18(15)23-19-8-4-2-6-16(19)22/h1-11,17,24H,12-13H2	RVEUDTXJLDUWSX-UHFFFAOYSA-N	50288548	2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-ethanol::CHEMBL100795	Endothelin-1 receptor			 900							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288548&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44213651	104130119		CHEMBL100795				ZINC11689465	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006011	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2c(OC)c(OC)ccc12	InChI=1S/C25H21NO6/c1-28-19-11-9-16-22(15-6-4-5-7-17(15)26-23(16)24(19)29-2)21(25(27)30-3)14-8-10-18-20(12-14)32-13-31-18/h4-12,21H,13H2,1-3H3	WJKGYOIXXYWTDD-UHFFFAOYSA-N	50288549	Benzo[1,3]dioxol-5-yl-(3,4-dimethoxy-acridin-9-yl)-acetic acid methyl ester::CHEMBL103975	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288549&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333056	104130120		CHEMBL103975				ZINC26821795	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006014	CC(C)(C)OC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C26H23NO4/c1-26(2,3)31-25(28)23(16-12-13-21-22(14-16)30-15-29-21)24-17-8-4-6-10-19(17)27-20-11-7-5-9-18(20)24/h4-14,23H,15H2,1-3H3	KTLCBCNCYPCXHN-UHFFFAOYSA-N	50288532	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid tert-butyl ester::CHEMBL100874	Endothelin-1 receptor			 66000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288532&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332578	104130103		CHEMBL100874				ZINC26753040	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006015	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2[n+]([O-])c2ccccc12	InChI=1S/C23H17NO5/c1-27-23(25)21(14-10-11-19-20(12-14)29-13-28-19)22-15-6-2-4-8-17(15)24(26)18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	YBEOAYIBFDLFOR-UHFFFAOYSA-N	50288542	Benzo[1,3]dioxol-5-yl-(10-oxy-acridin-9-yl)-acetic acid methyl ester::CHEMBL102348	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288542&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333055	104130113		CHEMBL102348				ZINC26818823	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006016	COC(=O)C(c1ccc2OCOc2c1)c1cc(C)nc2ccccc12	InChI=1S/C20H17NO4/c1-12-9-15(14-5-3-4-6-16(14)21-12)19(20(22)23-2)13-7-8-17-18(10-13)25-11-24-17/h3-10,19H,11H2,1-2H3	GTTDDHFXENWZAW-UHFFFAOYSA-N	50288545	Benzo[1,3]dioxol-5-yl-(2-methyl-quinolin-4-yl)-acetic acid methyl ester::CHEMBL103497	Endothelin-1 receptor			 61000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288545&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332803	104130116		CHEMBL103497				ZINC26818238	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006017	O=CC(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H15NO3/c24-12-17(14-9-10-20-21(11-14)26-13-25-20)22-15-5-1-3-7-18(15)23-19-8-4-2-6-16(19)22/h1-12,17H,13H2	QIHJVAFQIZXEHC-UHFFFAOYSA-N	50288543	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetaldehyde::CHEMBL103484	Endothelin-1 receptor			 20000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288543&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332577	104130114		CHEMBL103484				ZINC26815912	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006018	COC(=O)C(Cc1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C24H19NO4/c1-27-24(26)18(12-15-10-11-21-22(13-15)29-14-28-21)23-16-6-2-4-8-19(16)25-20-9-5-3-7-17(20)23/h2-11,13,18H,12,14H2,1H3	KXSQTEDQWJHEDB-UHFFFAOYSA-N	50288556	2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic acid methyl ester::CHEMBL100005	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288556&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332656	104130127		CHEMBL100005				ZINC26753052	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006019	NC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16N2O3/c23-22(25)20(13-9-10-18-19(11-13)27-12-26-18)21-14-5-1-3-7-16(14)24-17-8-4-2-6-15(17)21/h1-11,20H,12H2,(H2,23,25)	WGZNLQUCFSXCGZ-UHFFFAOYSA-N	50288536	2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-acetamide::CHEMBL100120	Endothelin-1 receptor			 77000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288536&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332624	104130107		CHEMBL100120				ZINC26749862	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006021	COC(=O)C(c1ccc(Cl)cc1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16ClNO2/c1-26-22(25)20(14-10-12-15(23)13-11-14)21-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)21/h2-13,20H,1H3	DRTRYUZPVGYJKT-UHFFFAOYSA-N	50288552	Acridin-9-yl-(4-chloro-phenyl)-acetic acid methyl ester::CHEMBL100756	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288552&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21559921	104130123		CHEMBL100756				ZINC26816014	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006022	COC(=O)C(c1ccc2OCOc2c1)c1c2CCCCc2nc2ccccc12	InChI=1S/C23H21NO4/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2,4,6,8,10-12,21H,3,5,7,9,13H2,1H3	OQUYJGQEHATGLA-UHFFFAOYSA-N	50288550	Benzo[1,3]dioxol-5-yl-(1,2,3,4-tetrahydro-acridin-9-yl)-acetic acid methyl ester::CHEMBL102494	Endothelin-1 receptor			 7300							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288550&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10452089	104130121		CHEMBL102494				ZINC26824012	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005997	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C23H17NO4/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	OOTHGTPTLCSOEZ-UHFFFAOYSA-N	50288537	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid methyl ester::CHEMBL320236	Endothelin-1 receptor			 5800							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288537&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9820754	104130108		CHEMBL320236				ZINC13906495	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005998	COc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1	InChI=1S/C30H23NO5/c1-33-21-13-10-19(11-14-21)17-34-30(32)28(20-12-15-26-27(16-20)36-18-35-26)29-22-6-2-4-8-24(22)31-25-9-5-3-7-23(25)29/h2-16,28H,17-18H2,1H3	XRBYSZSXEPYWSC-UHFFFAOYSA-N	50288541	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-methoxy-benzyl ester::CHEMBL101239	Endothelin-1 receptor			 34000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288541&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332638	104130112		CHEMBL101239				ZINC26752133	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50005999	Clc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1	InChI=1S/C29H20ClNO4/c30-20-12-9-18(10-13-20)16-33-29(32)27(19-11-14-25-26(15-19)35-17-34-25)28-21-5-1-3-7-23(21)31-24-8-4-2-6-22(24)28/h1-15,27H,16-17H2	BDQKQZBSECLBLP-UHFFFAOYSA-N	50288558	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-chloro-benzyl ester::CHEMBL101292	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332650	104130129		CHEMBL101292				ZINC26750945	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006000	OCC(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H17NO3/c24-12-17(14-9-10-20-21(11-14)26-13-25-20)22-15-5-1-3-7-18(15)23-19-8-4-2-6-16(19)22/h1-11,17,24H,12-13H2	RVEUDTXJLDUWSX-UHFFFAOYSA-N	50288548	2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-ethanol::CHEMBL100795	Endothelin-1 receptor			 900							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288548&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44213651	104130119		CHEMBL100795				ZINC11689465	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006001	Cc1cc(C(C(N)=O)c2ccc3OCOc3c2)c2ccccc2n1	InChI=1S/C19H16N2O3/c1-11-8-14(13-4-2-3-5-15(13)21-11)18(19(20)22)12-6-7-16-17(9-12)24-10-23-16/h2-9,18H,10H2,1H3,(H2,20,22)	HBEHERBGDLPFGC-UHFFFAOYSA-N	50288546	2-Benzo[1,3]dioxol-5-yl-2-(2-methyl-quinolin-4-yl)-acetamide::CHEMBL103886	Endothelin-1 receptor			 13000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288546&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332623	104130117		CHEMBL103886				ZINC26815675	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006003	COC(=O)C(Cc1c2ccccc2cc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C25H20O4/c1-27-25(26)21(18-10-11-23-24(13-18)29-15-28-23)14-22-19-8-4-2-6-16(19)12-17-7-3-5-9-20(17)22/h2-13,21H,14-15H2,1H3	WORMRQGTWISKMH-UHFFFAOYSA-N	50288534	3-Anthracen-9-yl-2-benzo[1,3]dioxol-5-yl-propionic acid methyl ester::CHEMBL103731	Endothelin-1 receptor			 76000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288534&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332641	104130105		CHEMBL103731				ZINC26818082	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006004	NC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16N2O3/c23-22(25)20(13-9-10-18-19(11-13)27-12-26-18)21-14-5-1-3-7-16(14)24-17-8-4-2-6-15(17)21/h1-11,20H,12H2,(H2,23,25)	WGZNLQUCFSXCGZ-UHFFFAOYSA-N	50288536	2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-acetamide::CHEMBL100120	Endothelin-1 receptor			 8500							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288536&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332624	104130107		CHEMBL100120				ZINC26749862	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006006	O=C(OCc1ccccc1)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C29H21NO4/c31-29(32-17-19-8-2-1-3-9-19)27(20-14-15-25-26(16-20)34-18-33-25)28-21-10-4-6-12-23(21)30-24-13-7-5-11-22(24)28/h1-16,27H,17-18H2	HWNMJOYXZVLVOL-UHFFFAOYSA-N	50288557	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid benzyl ester::CHEMBL316792	Endothelin-1 receptor			 57000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288557&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332807	104130128		CHEMBL316792				ZINC26821977	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006007	O=C(OCc1ccc2OCOc2c1)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C30H21NO6/c32-30(33-15-18-9-11-24-26(13-18)36-16-34-24)28(19-10-12-25-27(14-19)37-17-35-25)29-20-5-1-3-7-22(20)31-23-8-4-2-6-21(23)29/h1-14,28H,15-17H2	WDCUHHNJZSWUFN-UHFFFAOYSA-N	50288539	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid benzo[1,3]dioxol-5-ylmethyl ester::CHEMBL316648	Endothelin-1 receptor			 33000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288539&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332546	104130110		CHEMBL316648				ZINC26751656	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006008	COC(=O)C(c1ccc(Cl)cc1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16ClNO2/c1-26-22(25)20(14-10-12-15(23)13-11-14)21-16-6-2-4-8-18(16)24-19-9-5-3-7-17(19)21/h2-13,20H,1H3	DRTRYUZPVGYJKT-UHFFFAOYSA-N	50288552	Acridin-9-yl-(4-chloro-phenyl)-acetic acid methyl ester::CHEMBL100756	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288552&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21559921	104130123		CHEMBL100756				ZINC26816014	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006012	COC(=O)C(c1ccc2OCOc2c1)c1c2CCCCc2nc2ccccc12	InChI=1S/C23H21NO4/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2,4,6,8,10-12,21H,3,5,7,9,13H2,1H3	OQUYJGQEHATGLA-UHFFFAOYSA-N	50288550	Benzo[1,3]dioxol-5-yl-(1,2,3,4-tetrahydro-acridin-9-yl)-acetic acid methyl ester::CHEMBL102494	Endothelin-1 receptor			 12000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288550&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10452089	104130121		CHEMBL102494				ZINC26824012	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006013	C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C21H15NO2/c1-3-7-18-15(5-1)17(16-6-2-4-8-19(16)22-18)11-14-9-10-20-21(12-14)24-13-23-20/h1-10,12H,11,13H2	ZNIQDBVATXDCBV-UHFFFAOYSA-N	50288540	9-Benzo[1,3]dioxol-5-ylmethyl-acridine::CHEMBL99963	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288540&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332745	104130111		CHEMBL99963				ZINC26750931	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50013863	C\C=C\C=C\C(=O)O[C@@H]1C=C2COC(O)[C@]2(O)[C@@]2(C)CCCC(C)(C)C12	InChI=1S/C21H30O5/c1-5-6-7-9-16(22)26-15-12-14-13-25-18(23)21(14,24)20(4)11-8-10-19(2,3)17(15)20/h5-7,9,12,15,17-18,23-24H,8,10-11,13H2,1-4H3/b6-5+,9-7+/t15-,17?,18?,20+,21+/m1/s1	UJVJESYKEHAJNS-GJYYWCKTSA-N	50088850	(2E,4E)-Hexa-2,4-dienoic acid (5R,9aS,9bS)-1,9b-dihydroxy-6,6,9a-trimethyl-1,3,5,5a,6,7,8,9,9a,9b-decahydro-naphtho[1,2-c]furan-5-yl ester::CHEMBL353502	Endothelin-1 receptor			 50000							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088850&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383536	103987721		CHEMBL353502				ZINC28001169	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50017361	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H26N2O7S/c1-16(2)17-4-8-20(9-5-17)38(34,35)29-27(31)26(18-7-11-24-25(13-18)37-15-36-24)22-14-30(3)23-12-19(28(32)33)6-10-21(22)23/h4-14,16,26H,15H2,1-3H3,(H,29,31)(H,32,33)	SLRYYNVJPOWHGW-UHFFFAOYSA-N	50451439	CHEMBL2114305	Endothelin-1 receptor			 22							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451439&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738881	225145363		CHEMBL2114305					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027458	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(C)CO)c1	InChI=1S/C30H34N2O6/c1-16(2)31-25-10-8-22-26(18-5-9-23-24(13-18)38-15-37-23)28(30(34)35)27(29(22)32-25)21-7-6-20(36-4)12-19(21)11-17(3)14-33/h5-10,12-13,16-17,26-28,33H,11,14-15H2,1-4H3,(H,31,32)(H,34,35)/t17?,26-,27-,28+/m0/s1	KBHRSNOQJNLUNL-DULCMVPVSA-N	50141460	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL288247	Endothelin-1 receptor			 0.059000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141460&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284115	104030919		CHEMBL288247				ZINC29253550	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027460	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(C)C(=O)N(C)C)c1	InChI=1S/C32H37N3O6/c1-17(2)33-26-12-10-23-27(19-7-11-24-25(15-19)41-16-40-24)29(32(37)38)28(30(23)34-26)22-9-8-21(39-6)14-20(22)13-18(3)31(36)35(4)5/h7-12,14-15,17-18,27-29H,13,16H2,1-6H3,(H,33,34)(H,37,38)/t18?,27-,28-,29+/m0/s1	IDRPGYTWDRQQOE-NBNHAXFZSA-N	50141468	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-dimethylcarbamoyl-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL287683	Endothelin-1 receptor			 0.024000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141468&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284288	104030927		CHEMBL287683				ZINC29252219	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027464	COCC(C)Cc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C31H36N2O6/c1-17(2)32-26-11-9-23-27(19-6-10-24-25(14-19)39-16-38-24)29(31(34)35)28(30(23)33-26)22-8-7-21(37-5)13-20(22)12-18(3)15-36-4/h6-11,13-14,17-18,27-29H,12,15-16H2,1-5H3,(H,32,33)(H,34,35)/t18?,27-,28-,29+/m0/s1	HWNXCQQEFQWPHX-NBNHAXFZSA-N	50141472	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamino-7-[4-methoxy-2-(3-methoxy-2-methyl-propyl)-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL289634	Endothelin-1 receptor			 0.011000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141472&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284405	104030931		CHEMBL289634				ZINC38158217	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027467	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OC(C)CO)c1	InChI=1S/C29H32N2O7/c1-15(2)30-24-10-8-20-25(17-5-9-21-23(11-17)37-14-36-21)27(29(33)34)26(28(20)31-24)19-7-6-18(35-4)12-22(19)38-16(3)13-32/h5-12,15-16,25-27,32H,13-14H2,1-4H3,(H,30,31)(H,33,34)/t16?,25-,26-,27+/m0/s1	WERWDDKHJRXHAF-RNGUFSMASA-N	50141467	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy-1-methyl-ethoxy)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL289216	Endothelin-1 receptor			 0.057000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141467&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284041	104030926		CHEMBL289216				ZINC29318630	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027469	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(O)CO)c1	InChI=1S/C29H32N2O7/c1-15(2)30-24-9-7-21-25(16-4-8-22-23(12-16)38-14-37-22)27(29(34)35)26(28(21)31-24)20-6-5-19(36-3)11-17(20)10-18(33)13-32/h4-9,11-12,15,18,25-27,32-33H,10,13-14H2,1-3H3,(H,30,31)(H,34,35)/t18?,25-,26-,27+/m0/s1	HAZBSXKXEZHGFW-XZYOMFCLSA-N	50141461	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2,3-dihydroxy-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL286621	Endothelin-1 receptor			 0.048000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141461&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284437	104030920		CHEMBL286621				ZINC29251677	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039649	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CC)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-8-30(6)43(48(64)55-39(51(67)68)26-34-28-52-36-24-18-17-23-35(34)36)58-49(65)44(31(7)9-2)57-47(63)38(27-41(60)61)53-46(62)37(25-29(4)5)54-50(66)45(56-40(59)10-3)42(32-19-13-11-14-20-32)33-21-15-12-16-22-33/h11-24,28-31,37-39,42-45,52H,8-10,25-27H2,1-7H3,(H,53,62)(H,54,66)(H,55,64)(H,56,59)(H,57,63)(H,58,65)(H,60,61)(H,67,68)/t30-,31-,37-,38-,39-,43-,44-,45-/m0/s1	ASPXCZHJJMKYNZ-LCHPGPOGSA-N	50032184	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-[(S)-2-((S)-3,3-diphenyl-2-propionylamino-propionylamino)-4-methyl-pentanoylamino]-succinamic acid::CHEMBL323331	Endothelin-1 receptor			 1000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032184&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327659	103940734		CHEMBL323331					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039650	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C48H63N7O9/c1-7-28(5)41(46(61)53-37(48(63)64)24-32-26-50-34-22-16-15-21-33(32)34)55-47(62)42(29(6)8-2)54-44(59)36(25-38(56)57)51-43(58)35(23-27(3)4)52-45(60)40(49)39(30-17-11-9-12-18-30)31-19-13-10-14-20-31/h9-22,26-29,35-37,39-42,50H,7-8,23-25,49H2,1-6H3,(H,51,58)(H,52,60)(H,53,61)(H,54,59)(H,55,62)(H,56,57)(H,63,64)/t28-,29-,35-,36-,37-,40-,41-,42-/m0/s1	UFEOKDZSHDFLTG-SVTGUICBSA-N	50032197	(S)-3-[(S)-2-((S)-2-Amino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL319537	Endothelin-1 receptor			 2100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032197&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327660	103940747		CHEMBL319537					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039653	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H63N7O10/c1-8-29(6)42(47(63)54-38(49(65)66)24-33-26-50-35-22-16-15-21-34(33)35)56-46(62)41(28(4)5)55-45(61)37(25-39(58)59)52-44(60)36(23-27(2)3)53-48(64)43(51-30(7)57)40(31-17-11-9-12-18-31)32-19-13-10-14-20-32/h9-22,26-29,36-38,40-43,50H,8,23-25H2,1-7H3,(H,51,57)(H,52,60)(H,53,64)(H,54,63)(H,55,61)(H,56,62)(H,58,59)(H,65,66)/t29-,36-,37-,38-,41-,42-,43-/m0/s1	DRQGVADKIBRYTL-KNTSQTEZSA-N	50032207	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-propyl)-succinamic acid::CHEMBL319660	Endothelin-1 receptor			 17							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032207&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327892	103940757		CHEMBL319660					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039655	CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H69N7O10/c1-6-32(4)46(51(67)59-43(53(69)70)28-37-30-54-39-25-17-16-24-38(37)39)60-50(66)41(27-34-18-10-7-11-19-34)56-49(65)42(29-44(62)63)57-48(64)40(26-31(2)3)58-52(68)47(55-33(5)61)45(35-20-12-8-13-21-35)36-22-14-9-15-23-36/h8-9,12-17,20-25,30-32,34,40-43,45-47,54H,6-7,10-11,18-19,26-29H2,1-5H3,(H,55,61)(H,56,65)(H,57,64)(H,58,68)(H,59,67)(H,60,66)(H,62,63)(H,69,70)/t32-,40-,41-,42-,43-,46-,47-/m0/s1	JIWCCEBFSJAHKC-UJGVUKHOSA-N	50032190	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-cyclohexyl-ethyl)-succinamic acid::CHEMBL263295	Endothelin-1 receptor			 650							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032190&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327891	103940740		CHEMBL263295					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039656	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-7-27(4)40(45(61)53-37(47(63)64)23-32-25-48-34-21-15-14-20-33(32)34)54-42(58)28(5)49-43(59)36(24-38(56)57)51-44(60)35(22-26(2)3)52-46(62)41(50-29(6)55)39(30-16-10-8-11-17-30)31-18-12-9-13-19-31/h8-21,25-28,35-37,39-41,48H,7,22-24H2,1-6H3,(H,49,59)(H,50,55)(H,51,60)(H,52,62)(H,53,61)(H,54,58)(H,56,57)(H,63,64)/t27-,28-,35-,36-,37-,40-,41-/m0/s1	LHABXBWIIYUERU-WJEZPDPISA-N	50032186	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-ethyl)-succinamic acid::CHEMBL94907	Endothelin-1 receptor			 100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032186&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327870	103940736		CHEMBL94907					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039657	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O	InChI=1S/C50H66N8O9/c1-8-29(5)42(48(65)54-37(45(51)62)25-34-27-52-36-23-17-16-22-35(34)36)58-49(66)43(30(6)9-2)57-47(64)39(26-40(60)61)55-46(63)38(24-28(3)4)56-50(67)44(53-31(7)59)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,52H,8-9,24-26H2,1-7H3,(H2,51,62)(H,53,59)(H,54,65)(H,55,63)(H,56,67)(H,57,64)(H,58,66)(H,60,61)/t29-,30-,37-,38-,39-,42-,43-,44-/m0/s1	OAUGIJWXGIUSTE-SRYIDKSASA-N	50032183	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL329609	Endothelin-1 receptor			 320							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032183&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327876	103940733		CHEMBL329609					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039660	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O10/c1-6-31(3)45(50(66)58-42(53(69)70)28-37-30-54-39-26-18-17-25-38(37)39)60-51(67)46(32(4)7-2)59-49(65)41(29-43(62)63)56-48(64)40(27-34-19-11-8-12-20-34)57-52(68)47(55-33(5)61)44(35-21-13-9-14-22-35)36-23-15-10-16-24-36/h8-26,30-32,40-42,44-47,54H,6-7,27-29H2,1-5H3,(H,55,61)(H,56,64)(H,57,68)(H,58,66)(H,59,65)(H,60,67)(H,62,63)(H,69,70)/t31-,32-,40+,41-,42-,45-,46-,47-/m0/s1	HZVYDMKAAHZAMV-LJDWDNFTSA-N	50032170	(S)-3-[(R)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-3-phenyl-propionylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL411797	Endothelin-1 receptor			 520							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032170&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328018	103940720		CHEMBL411797					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039663	CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-8-30(5)43(48(64)56-40(51(67)68)27-35-28-52-37-23-17-16-22-36(35)37)58-49(65)44(31(6)9-2)57-46(62)38(24-25-41(60)61)54-47(63)39(26-29(3)4)55-50(66)45(53-32(7)59)42(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,28-31,38-40,42-45,52H,8-9,24-27H2,1-7H3,(H,53,59)(H,54,63)(H,55,66)(H,56,64)(H,57,62)(H,58,65)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	WXIDXBSXUCQMKX-KUIIPSLPSA-N	50032191	(S)-4-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-4-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butylcarbamoyl)-butyric acid::CHEMBL433349	Endothelin-1 receptor			 430							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032191&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328089	103940741		CHEMBL433349					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039664	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O8/c1-9-29(5)41(46(60)54-39(49(63)64)26-35-27-50-37-24-18-17-23-36(35)37)56-47(61)42(30(6)10-2)55-44(58)31(7)51-45(59)38(25-28(3)4)53-48(62)43(52-32(8)57)40(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,27-31,38-43,50H,9-10,25-26H2,1-8H3,(H,51,59)(H,52,57)(H,53,62)(H,54,60)(H,55,58)(H,56,61)(H,63,64)/t29-,30-,31-,38-,39-,41-,42-,43-/m0/s1	NKXZGLUBJIDNGG-BSUGJTRNSA-N	50032202	(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL319719	Endothelin-1 receptor			 35							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328092	103940752		CHEMBL319719					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039665	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H69N7O8/c1-8-34(5)47(52(66)60-45(55(69)70)31-40-32-56-42-28-20-19-27-41(40)42)62-53(67)48(35(6)9-2)61-51(65)44(30-37-21-13-10-14-22-37)58-50(64)43(29-33(3)4)59-54(68)49(57-36(7)63)46(38-23-15-11-16-24-38)39-25-17-12-18-26-39/h10-28,32-35,43-49,56H,8-9,29-31H2,1-7H3,(H,57,63)(H,58,64)(H,59,68)(H,60,66)(H,61,65)(H,62,67)(H,69,70)/t34-,35-,43-,44-,45-,47-,48-,49-/m0/s1	WTUKWAHKXMTYEJ-GEAHHQELSA-N	50032180	(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL216082	Endothelin-1 receptor			 840							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032180&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328087	103940730		CHEMBL216082					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039666	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O	InChI=1S/C48H64N6O11/c1-8-28(5)40(45(61)52-37(48(64)65)25-31-20-22-34(56)23-21-31)54-46(62)41(29(6)9-2)53-44(60)36(26-38(57)58)50-43(59)35(24-27(3)4)51-47(63)42(49-30(7)55)39(32-16-12-10-13-17-32)33-18-14-11-15-19-33/h10-23,27-29,35-37,39-42,56H,8-9,24-26H2,1-7H3,(H,49,55)(H,50,59)(H,51,63)(H,52,61)(H,53,60)(H,54,62)(H,57,58)(H,64,65)/t28-,29-,35-,36-,37-,40-,41-,42-/m0/s1	QXIDYPVHAGHZKK-SVTGUICBSA-N	50032210	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[1-carboxy-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL2370254	Endothelin-1 receptor			 2200							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032210&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73348481	103940760		CHEMBL2370254					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039667	CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C52H72N8O8/c1-8-32(5)44(49(64)58-42(52(67)68)29-37-30-54-39-25-17-16-24-38(37)39)60-50(65)45(33(6)9-2)59-47(62)40(26-18-19-27-53)56-48(63)41(28-31(3)4)57-51(66)46(55-34(7)61)43(35-20-12-10-13-21-35)36-22-14-11-15-23-36/h10-17,20-25,30-33,40-46,54H,8-9,18-19,26-29,53H2,1-7H3,(H,55,61)(H,56,63)(H,57,66)(H,58,64)(H,59,62)(H,60,65)(H,67,68)/t32-,33-,40-,41-,42-,44-,45-,46+/m0/s1	WGLAFABBGWXLCX-LGNPPWGXSA-N	50032205	(S)-2-[(2S,3S)-2-((2S,3S)-2-{2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-6-amino-hexanoylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL2370255	Endothelin-1 receptor			 480							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032205&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10102342	103940755		CHEMBL2370255					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039669	CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H61N7O12/c1-6-28(4)42(47(65)55-38(49(67)68)24-32-26-50-34-20-14-13-19-33(32)34)56-44(62)35(21-22-39(58)59)52-46(64)37(25-40(60)61)53-45(63)36(23-27(2)3)54-48(66)43(51-29(5)57)41(30-15-9-7-10-16-30)31-17-11-8-12-18-31/h7-20,26-28,35-38,41-43,50H,6,21-25H2,1-5H3,(H,51,57)(H,52,64)(H,53,63)(H,54,66)(H,55,65)(H,56,62)(H,58,59)(H,60,61)(H,67,68)/t28-,35-,36-,37-,38-,42-,43-/m0/s1	HTKJJFQSPQJMIW-NUFMZFPJSA-N	50032176	(S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-carboxy-propionylamino}-4-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-butyric acid::CHEMBL318020	Endothelin-1 receptor			 1000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032176&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328091	103940726		CHEMBL318020					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039670	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(O)=O	InChI=1S/C48H64N6O10/c1-8-29(5)40(45(60)52-37(48(63)64)26-32-19-13-10-14-20-32)54-46(61)41(30(6)9-2)53-44(59)36(27-38(56)57)50-43(58)35(25-28(3)4)51-47(62)42(49-31(7)55)39(33-21-15-11-16-22-33)34-23-17-12-18-24-34/h10-24,28-30,35-37,39-42H,8-9,25-27H2,1-7H3,(H,49,55)(H,50,58)(H,51,62)(H,52,60)(H,53,59)(H,54,61)(H,56,57)(H,63,64)/t29-,30-,35-,36-,37-,40-,41-,42-/m0/s1	KSOJBBDKSAOOMV-ZHTTVDOBSA-N	50032217	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(1S,2S)-1-[(1S,2S)-1-(1-carboxy-2-phenyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::CHEMBL2370253	Endothelin-1 receptor			 5000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032217&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73345452	103940767		CHEMBL2370253					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039671	CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N8O10/c1-6-30(4)43(48(65)57-40(50(67)68)26-34-28-52-36-22-14-13-21-35(34)36)58-45(62)37(23-15-16-24-51)54-47(64)39(27-41(60)61)55-46(63)38(25-29(2)3)56-49(66)44(53-31(5)59)42(32-17-9-7-10-18-32)33-19-11-8-12-20-33/h7-14,17-22,28-30,37-40,42-44,52H,6,15-16,23-27,51H2,1-5H3,(H,53,59)(H,54,64)(H,55,63)(H,56,66)(H,57,65)(H,58,62)(H,60,61)(H,67,68)/t30-,37-,38-,39-,40-,43-,44-/m0/s1	ALWPEEGNMHILML-VVKSDJSFSA-N	50032199	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-5-amino-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-pentyl)-succinamic acid::CHEMBL94525	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032199&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328090	103940749		CHEMBL94525					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039674	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)NC)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N8O10/c1-8-29(5)41(46(63)55-38(49(66)67)25-33-27-52-35-23-17-16-22-34(33)35)57-47(64)42(30(6)9-2)56-45(62)37(26-39(59)60)53-44(61)36(24-28(3)4)54-48(65)43(58-50(68)51-7)40(31-18-12-10-13-19-31)32-20-14-11-15-21-32/h10-23,27-30,36-38,40-43,52H,8-9,24-26H2,1-7H3,(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)(H2,51,58,68)/t29-,30-,36-,37-,38-,41-,42-,43-/m0/s1	PIENNYPWHMRMAZ-MVMSJIHBSA-N	50032178	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-4-methyl-2-[(S)-2-(3-methyl-ureido)-3,3-diphenyl-propionylamino]-pentanoylamino}-succinamic acid::CHEMBL433406	Endothelin-1 receptor			 280							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032178&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327821	103940728		CHEMBL433406					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039675	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O10/c1-6-32(4)46(51(67)59-43(53(69)70)28-37-30-54-39-25-17-16-24-38(37)39)60-50(66)41(27-34-18-10-7-11-19-34)56-49(65)42(29-44(62)63)57-48(64)40(26-31(2)3)58-52(68)47(55-33(5)61)45(35-20-12-8-13-21-35)36-22-14-9-15-23-36/h7-25,30-32,40-43,45-47,54H,6,26-29H2,1-5H3,(H,55,61)(H,56,65)(H,57,64)(H,58,68)(H,59,67)(H,60,66)(H,62,63)(H,69,70)/t32-,40-,41-,42-,43-,46-,47-/m0/s1	BMROGBGRQLVZIB-UJGVUKHOSA-N	50032208	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-phenyl-ethyl)-succinamic acid::CHEMBL265116	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032208&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327903	103940758		CHEMBL265116					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039676	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C1c2ccccc2CCc2ccccc12)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C52H67N7O10/c1-8-29(5)44(49(65)57-41(52(68)69)25-34-27-53-38-21-15-14-18-35(34)38)59-50(66)45(30(6)9-2)58-48(64)40(26-42(61)62)55-47(63)39(24-28(3)4)56-51(67)46(54-31(7)60)43-36-19-12-10-16-32(36)22-23-33-17-11-13-20-37(33)43/h10-21,27-30,39-41,43-46,53H,8-9,22-26H2,1-7H3,(H,54,60)(H,55,63)(H,56,67)(H,57,65)(H,58,64)(H,59,66)(H,61,62)(H,68,69)/t29-,30-,39-,40-,41-,44-,45-,46-/m0/s1	HRAQSWKGRRUBDJ-FFEQYNEASA-N	50032181	2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl(methylcarboxamido)methylcarboxamido]-3-methylbutylcarboxamido}ethylcarboxamido)-2-methylbutylcarboxamido]-2-methylbutylcarboxamido}-3-(1H-3-indolyl)propanoic acid::3-{2-[2-Acetylamino-2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-acetylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL262993	Endothelin-1 receptor			 3.5							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032181&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44304492	103940731		CHEMBL262993					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039677	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N10O10/c1-6-28(3)41(46(66)58-38(49(69)70)25-33-27-54-35-22-15-14-21-34(33)35)60-47(67)42(29(4)7-2)59-45(65)37(26-39(62)63)57-44(64)36(23-16-24-53-50(51)52)56-48(68)43(55-30(5)61)40(31-17-10-8-11-18-31)32-19-12-9-13-20-32/h8-15,17-22,27-29,36-38,40-43,54H,6-7,16,23-26H2,1-5H3,(H,55,61)(H,56,68)(H,57,64)(H,58,66)(H,59,65)(H,60,67)(H,62,63)(H,69,70)(H4,51,52,53)/t28-,29-,36-,37-,38-,41-,42-,43-/m0/s1	YOMSYVFQYBPECD-TYTHOBKFSA-N	50032175	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-5-guanidino-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL405599	Endothelin-1 receptor			 14							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032175&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10463627	103940725		CHEMBL405599					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039679	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-30(6)43(48(64)54-38(24-29(4)5)46(62)56-40(50(66)67)25-34-27-51-36-22-16-15-21-35(34)36)57-47(63)39(26-41(59)60)53-45(61)37(23-28(2)3)55-49(65)44(52-31(7)58)42(32-17-11-9-12-18-32)33-19-13-10-14-20-33/h9-22,27-30,37-40,42-44,51H,8,23-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,64)(H,55,65)(H,56,62)(H,57,63)(H,59,60)(H,66,67)/t30-,37-,38-,39-,40-,43-,44-/m0/s1	PPBOBEGAVCYYSB-VVKSDJSFSA-N	50032174	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL97431	Endothelin-1 receptor			 230							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032174&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328042	103940724		CHEMBL97431					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039680	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N8O10/c1-6-30(4)43(48(65)54-37(23-15-16-24-51)45(62)57-40(50(67)68)26-34-28-52-36-22-14-13-21-35(34)36)58-47(64)39(27-41(60)61)55-46(63)38(25-29(2)3)56-49(66)44(53-31(5)59)42(32-17-9-7-10-18-32)33-19-11-8-12-20-33/h7-14,17-22,28-30,37-40,42-44,52H,6,15-16,23-27,51H2,1-5H3,(H,53,59)(H,54,65)(H,55,63)(H,56,66)(H,57,62)(H,58,64)(H,60,61)(H,67,68)/t30-,37-,38-,39-,40-,43-,44-/m0/s1	IKSOLGRXWOFPDB-VVKSDJSFSA-N	50032169	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-5-amino-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-pentylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL431433	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032169&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327779	103940719		CHEMBL431433					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039682	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O10/c1-6-32(4)46(51(67)58-41(27-34-18-10-7-11-19-34)49(65)59-43(53(69)70)28-37-30-54-39-25-17-16-24-38(37)39)60-50(66)42(29-44(62)63)56-48(64)40(26-31(2)3)57-52(68)47(55-33(5)61)45(35-20-12-8-13-21-35)36-22-14-9-15-23-36/h7-25,30-32,40-43,45-47,54H,6,26-29H2,1-5H3,(H,55,61)(H,56,64)(H,57,68)(H,58,67)(H,59,65)(H,60,66)(H,62,63)(H,69,70)/t32-,40-,41-,42-,43-,46-,47-/m0/s1	YSXSBXCLZOAQIO-UJGVUKHOSA-N	50032204	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL405709	Endothelin-1 receptor			 4000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032204&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327778	103940754		CHEMBL405709					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039683	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H61N7O12/c1-6-27(3)41(46(64)54-37(49(67)68)24-32-26-50-34-21-15-14-20-33(32)34)56-47(65)42(28(4)7-2)55-45(63)36(25-39(60)61)53-44(62)35(22-23-38(58)59)52-48(66)43(51-29(5)57)40(30-16-10-8-11-17-30)31-18-12-9-13-19-31/h8-21,26-28,35-37,40-43,50H,6-7,22-25H2,1-5H3,(H,51,57)(H,52,66)(H,53,62)(H,54,64)(H,55,63)(H,56,65)(H,58,59)(H,60,61)(H,67,68)/t27-,28-,35-,36-,37-,41-,42-,43-/m0/s1	OVTDDVGHCAWGJB-CVEDHXPHSA-N	50032171	(S)-4-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-[(S)-2-carboxy-1-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-butyric acid::CHEMBL97470	Endothelin-1 receptor			 25							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032171&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327438	103940721		CHEMBL97470					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039684	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35-,36-,37-,38-,40-,41-/m0/s1	GNRBLKLDFZWDTC-RPEMCHKGSA-N	50032166	(S)-3-[(S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL317099	Endothelin-1 receptor			 2100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032166&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327853	103940716		CHEMBL317099					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039686	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H64N8O10/c1-6-28(3)41(46(63)55-38(49(66)67)25-33-27-51-35-22-15-14-21-34(33)35)57-47(64)42(29(4)7-2)56-45(62)37(26-39(59)60)54-44(61)36(23-16-24-50)53-48(65)43(52-30(5)58)40(31-17-10-8-11-18-31)32-19-12-9-13-20-32/h8-15,17-22,27-29,36-38,40-43,51H,6-7,16,23-26,50H2,1-5H3,(H,52,58)(H,53,65)(H,54,61)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t28-,29-,36-,37-,38-,41-,42-,43-/m0/s1	IEJDKICPBODJMQ-TYTHOBKFSA-N	50032193	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-5-amino-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL94983	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032193&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327437	103940743		CHEMBL94983					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039687	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30-,37-,38-,39-,42-,43-,44-/m0/s1	XUMJJSAQQCTKAO-SRYIDKSASA-N	50032172	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL328942	Endothelin-1 receptor			 70							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032172&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9897720	103940722		CHEMBL328942					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039689	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NS(C)(=O)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O11S/c1-8-29(5)41(46(61)53-38(49(64)65)25-33-27-50-35-23-17-16-22-34(33)35)55-47(62)42(30(6)9-2)54-45(60)37(26-39(57)58)51-44(59)36(24-28(3)4)52-48(63)43(56-68(7,66)67)40(31-18-12-10-13-19-31)32-20-14-11-15-21-32/h10-23,27-30,36-38,40-43,50,56H,8-9,24-26H2,1-7H3,(H,51,59)(H,52,63)(H,53,61)(H,54,60)(H,55,62)(H,57,58)(H,64,65)/t29-,30-,36-,37-,38-,41-,42-,43-/m0/s1	XSVMSRFRFMDPSQ-MVMSJIHBSA-N	50032189	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-[(S)-2-((S)-2-methanesulfonylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-succinamic acid::CHEMBL96822	Endothelin-1 receptor			 540							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032189&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327628	103940739		CHEMBL96822					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50039690	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(F)(F)F)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H62F3N7O10/c1-7-28(5)40(45(65)57-37(48(68)69)24-32-26-54-34-22-16-15-21-33(32)34)59-46(66)41(29(6)8-2)58-44(64)36(25-38(61)62)55-43(63)35(23-27(3)4)56-47(67)42(60-49(70)50(51,52)53)39(30-17-11-9-12-18-30)31-19-13-10-14-20-31/h9-22,26-29,35-37,39-42,54H,7-8,23-25H2,1-6H3,(H,55,63)(H,56,67)(H,57,65)(H,58,64)(H,59,66)(H,60,70)(H,61,62)(H,68,69)/t28-,29-,35-,36-,37-,40-,41-,42-/m0/s1	QCRZVRDNUAFXCL-SVTGUICBSA-N	50032212	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-2-[(S)-3,3-diphenyl-2-(2,2,2-trifluoro-acetylamino)-propionylamino]-4-methyl-pentanoylamino}-succinamic acid::CHEMBL386181	Endothelin-1 receptor			 1700							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032212&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327656	103940762		CHEMBL386181					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50037870	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor		 55								ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50037871	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor			 570							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50042591	Cc1[nH]c2ccccc2c1C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC1=O)C1CCCC1)C1CC1	InChI=1S/C33H42N6O7/c1-17-21(20-9-4-5-10-22(20)34-17)15-23-29(42)36-24(16-26(40)41)33(46)39-14-6-11-25(39)30(43)37-27(18-7-2-3-8-18)32(45)38-28(19-12-13-19)31(44)35-23/h4-5,9-10,18-19,23-25,27-28,34H,2-3,6-8,11-16H2,1H3,(H,35,44)(H,36,42)(H,37,43)(H,38,45)(H,40,41)/t23-,24+,25-,27-,28+/m0/s1	DURQGRPWKJTJCL-YTFMROOWSA-N	50051404	CHEMBL312541::[14-Cyclopentyl-11-cyclopropyl-8-(2-methyl-1H-indol-3-ylmethyl)-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor			 2.9							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051404&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314802	103948402		CHEMBL312541				ZINC26388406	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50042594	CSC(C)(C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2c([nH]c3ccccc23)C#N)NC(=O)[C@H](NC1=O)C(C)C	InChI=1S/C32H41N7O7S/c1-16(2)25-29(44)35-20(13-18-17-9-6-7-10-19(17)34-22(18)15-33)27(42)36-21(14-24(40)41)31(46)39-12-8-11-23(39)28(43)38-26(30(45)37-25)32(3,4)47-5/h6-7,9-10,16,20-21,23,25-26,34H,8,11-14H2,1-5H3,(H,35,44)(H,36,42)(H,37,45)(H,38,43)(H,40,41)/t20-,21+,23-,25+,26+/m0/s1	ZAKOLOWBBBGFHG-YHWCJKPGSA-N	50422142	CHEMBL2304017	Endothelin-1 receptor			 6200							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422142&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71719083	164151017		CHEMBL2304017				ZINC95564993	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50042596	OC(=O)C[C@H]1NC(=O)[C@H](Cc2c(Br)[nH]c3ccccc23)NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C1=O)C1CCCC1)C1CC1	InChI=1S/C32H39BrN6O7/c33-27-19(18-8-3-4-9-20(18)34-27)14-21-28(42)36-22(15-24(40)41)32(46)39-13-5-10-23(39)29(43)37-25(16-6-1-2-7-16)31(45)38-26(17-11-12-17)30(44)35-21/h3-4,8-9,16-17,21-23,25-26,34H,1-2,5-7,10-15H2,(H,35,44)(H,36,42)(H,37,43)(H,38,45)(H,40,41)/t21-,22+,23-,25-,26+/m0/s1	OBNJEEOFTPJHQY-RPEQPCMISA-N	50051389	CHEMBL74277::[8-(2-Bromo-1H-indol-3-ylmethyl)-14-cyclopentyl-11-cyclopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor			 8.6							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051389&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314173	103948387		CHEMBL74277				ZINC26389461	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50043839	CC(C)C[C@H]1NC(=O)[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C1CCCC1	InChI=1S/C33H44N6O7/c1-18(2)14-23-29(42)35-24(15-20-17-34-22-11-6-5-10-21(20)22)30(43)37-25(16-27(40)41)33(46)39-13-7-12-26(39)31(44)38-28(32(45)36-23)19-8-3-4-9-19/h5-6,10-11,17-19,23-26,28,34H,3-4,7-9,12-16H2,1-2H3,(H,35,42)(H,36,45)(H,37,43)(H,38,44)(H,40,41)/t23-,24+,25+,26-,28+/m1/s1	BVAWPBTZOQZBSS-YTZVEHKTSA-N	50029354	CHEMBL133257::[(5S,8S,11R,14S,16aR)-14-Cyclopentyl-8-(1H-indol-3-ylmethyl)-11-isobutyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor			 3.4							ChEMBL	10.1021/jm00021a021	10.7270/Q2D50M0H	7473559			Fukami, T; Nagase, T; Fujita, K; Hayama, T; Niiyama, K; Mase, T; Nakajima, S; Fukuroda, T; Saeki, T; Nishikibe, M	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029354&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44357132	103938425		CHEMBL133257				ZINC27427082	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50043843	CC(C)C[C@H]1NC(=O)[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C30H42N6O8S/c1-16(2)12-21-26(37)32-22(13-18-14-31-20-9-6-5-8-19(18)20)27(38)34-23(15-45(42,43)44)30(41)36-11-7-10-24(36)28(39)35-25(17(3)4)29(40)33-21/h5-6,8-9,14,16-17,21-25,31H,7,10-13,15H2,1-4H3,(H,32,37)(H,33,40)(H,34,38)(H,35,39)(H,42,43,44)/t21-,22+,23+,24-,25+/m1/s1	BDGDGFUNKMWECN-MQZWXTIWSA-N	50029351	CHEMBL342615::[(5R,8S,11R,14S,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-methanesulfonic acid	Endothelin-1 receptor			 30							ChEMBL	10.1021/jm00021a021	10.7270/Q2D50M0H	7473559			Fukami, T; Nagase, T; Fujita, K; Hayama, T; Niiyama, K; Mase, T; Nakajima, S; Fukuroda, T; Saeki, T; Nishikibe, M	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029351&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44357212	103938422		CHEMBL342615			C15521	ZINC27432504	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50043845	CC(C)C[C@H]1NC(=O)[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m1/s1	VYCMAAOURFJIHD-XPICPDFBSA-N	50029352	CHEMBL336033::[(5S,8S,11R,14S,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor			 8.3							ChEMBL	10.1021/jm00021a021	10.7270/Q2D50M0H	7473559			Fukami, T; Nagase, T; Fujita, K; Hayama, T; Niiyama, K; Mase, T; Nakajima, S; Fukuroda, T; Saeki, T; Nishikibe, M	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029352&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44357174	103938423		CHEMBL336033				ZINC04535642	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50043847	CC[C@H](C)[C@@H]1NC(=O)[C@@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC(C)C)NC1=O	InChI=1S/C31H44N6O7/c1-6-17(4)26-31(44)36-23(13-16(2)3)29(42)35-24(14-19-15-32-21-10-8-7-9-20(19)21)30(43)34-22(11-12-25(38)39)28(41)33-18(5)27(40)37-26/h7-10,15-18,22-24,26,32H,6,11-14H2,1-5H3,(H,33,41)(H,34,43)(H,35,42)(H,36,44)(H,37,40)(H,38,39)/t17-,18+,22-,23+,24-,26-/m0/s1	UMKHUVRCCMAOBN-OTPQXUHPSA-N	50029355	3-[(2S,5R,8S,11R,14S)-8-((S)-sec-Butyl)-14-(1H-indol-3-ylmethyl)-11-isobutyl-5-methyl-3,6,9,12,15-pentaoxo-1,4,7,10,13pentaaza-cyclopentadec-2-yl]-propionic acid::CHEMBL343379	Endothelin-1 receptor			 590							ChEMBL	10.1021/jm00021a021	10.7270/Q2D50M0H	7473559			Fukami, T; Nagase, T; Fujita, K; Hayama, T; Niiyama, K; Mase, T; Nakajima, S; Fukuroda, T; Saeki, T; Nishikibe, M	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029355&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44357035	103938426		CHEMBL343379				ZINC27431004	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50043848	CC(C)C[C@H]1NC(=O)[C@@H](NC(=O)[C@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)c1cccs1	InChI=1S/C32H38N6O7S/c1-17(2)13-21-28(41)34-22(14-18-16-33-20-8-4-3-7-19(18)20)29(42)36-23(15-26(39)40)32(45)38-11-5-9-24(38)30(43)37-27(31(44)35-21)25-10-6-12-46-25/h3-4,6-8,10,12,16-17,21-24,27,33H,5,9,11,13-15H2,1-2H3,(H,34,41)(H,35,44)(H,36,42)(H,37,43)(H,39,40)/t21-,22+,23+,24-,27+/m1/s1	KXUDUVUGZWJNHV-PFGYYQCGSA-N	50029353	CHEMBL414165::[(5S,8S,11R,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-4,7,10,13,16-pentaoxo-14-thiophen-2-yl-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor			 1.2							ChEMBL	10.1021/jm00021a021	10.7270/Q2D50M0H	7473559			Fukami, T; Nagase, T; Fujita, K; Hayama, T; Niiyama, K; Mase, T; Nakajima, S; Fukuroda, T; Saeki, T; Nishikibe, M	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029353&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44357391	103938424		CHEMBL414165				ZINC27436833	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041672	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(C)cc2)cc1	InChI=1S/C26H24O5/c1-17-4-8-19(9-5-17)24-23(16-18-6-12-21(29-2)13-7-18)26(28,31-25(24)27)20-10-14-22(30-3)15-11-20/h4-15,28H,16H2,1-3H3	OKZRQVZTVLKRLK-UHFFFAOYSA-N	50034262	5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-p-tolyl-5H-furan-2-one::CHEMBL10951	Endothelin-1 receptor			 750							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10047521	103942463		CHEMBL10951				ZINC13740971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041673	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(OC)cc2)cc1	InChI=1S/C26H24O6/c1-29-20-10-4-17(5-11-20)16-23-24(18-6-12-21(30-2)13-7-18)25(27)32-26(23,28)19-8-14-22(31-3)15-9-19/h4-15,28H,16H2,1-3H3	JCPFQTABMZGRMJ-UHFFFAOYSA-N	50034268	5-Hydroxy-4-(4-methoxy-benzyl)-3,5-bis-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11162	Endothelin-1 receptor			 190							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034268&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10410546	103942469		CHEMBL11162				ZINC13740969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041674	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(OC)c(C)c1)c1ccc2OCOc2c1	InChI=1S/C27H24O7/c1-16-12-17(4-10-22(16)31-3)13-21-25(18-5-11-23-24(14-18)33-15-32-23)26(28)34-27(21,29)19-6-8-20(30-2)9-7-19/h4-12,14,29H,13,15H2,1-3H3	LCTRHYXOTRTJQR-UHFFFAOYSA-N	50034269	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-3-methyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10924	Endothelin-1 receptor			 2.4							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034269&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9890440	103942470		CHEMBL10924				ZINC13740963	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041675	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(C)cc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-16-3-5-17(6-4-16)13-21-24(18-7-12-22-23(14-18)31-15-30-22)25(27)32-26(21,28)19-8-10-20(29-2)11-9-19/h3-12,14,28H,13,15H2,1-2H3	SGMHXYMWOLAIMX-UHFFFAOYSA-N	50034265	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-methyl-benzyl)-5H-furan-2-one::CHEMBL10374	Endothelin-1 receptor			 51							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9845562	103942466		CHEMBL10374				ZINC13740961	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041676	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccccc2)cc1	InChI=1S/C25H22O5/c1-28-20-12-8-17(9-13-20)16-22-23(18-6-4-3-5-7-18)24(26)30-25(22,27)19-10-14-21(29-2)15-11-19/h3-15,27H,16H2,1-2H3	GCLJDQQEPIRTNF-UHFFFAOYSA-N	50034261	5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL10897	Endothelin-1 receptor			 2200							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034261&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10024044	103942462		CHEMBL10897				ZINC13740965	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041677	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)cc1	InChI=1S/C24H17ClO5/c25-18-9-7-17(8-10-18)24(27)19(12-15-4-2-1-3-5-15)22(23(26)30-24)16-6-11-20-21(13-16)29-14-28-20/h1-11,13,27H,12,14H2	HIOIBSDPMJWBMG-UHFFFAOYSA-N	50034257	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-chloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL267094	Endothelin-1 receptor			 2200							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070783	103942458		CHEMBL267094				ZINC13740947	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041678	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1ccc2OCOc2c1	InChI=1S/C25H19ClO6/c1-29-19-9-5-17(6-10-19)25(28)20(12-15-2-7-18(26)8-3-15)23(24(27)32-25)16-4-11-21-22(13-16)31-14-30-21/h2-11,13,28H,12,14H2,1H3	BIXNVCGHAZAOLY-UHFFFAOYSA-N	50034264	3-Benzo[1,3]dioxol-5-yl-4-(4-chloro-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10733	Endothelin-1 receptor			 110							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11744509	103942465		CHEMBL10733				ZINC13740957	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041679	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-28-19-10-8-18(9-11-19)25(27)20(13-16-5-3-2-4-6-16)23(24(26)31-25)17-7-12-21-22(14-17)30-15-29-21/h2-12,14,27H,13,15H2,1H3	JZHLIUOZBXWYGJ-UHFFFAOYSA-N	50034256	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL274383::PD-155080	Endothelin-1 receptor			 7.4							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034256&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11742628	103942457		CHEMBL274383				ZINC13740949	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041680	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)c(Cl)c1	InChI=1S/C24H16Cl2O5/c25-18-8-7-16(12-19(18)26)24(28)17(10-14-4-2-1-3-5-14)22(23(27)31-24)15-6-9-20-21(11-15)30-13-29-20/h1-9,11-12,28H,10,13H2	GTADCEYWHLRYOB-UHFFFAOYSA-N	50034260	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dichloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL275991	Endothelin-1 receptor			 400							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10027018	103942461		CHEMBL275991				ZINC13740953	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041681	Cc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O5/c1-16-7-10-19(11-8-16)25(27)20(13-17-5-3-2-4-6-17)23(24(26)30-25)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,27H,13,15H2,1H3	HUUWRVJBRKRKHX-UHFFFAOYSA-N	50034258	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tolyl-5H-furan-2-one::CHEMBL273613	Endothelin-1 receptor			 1200							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9865706	103942459		CHEMBL273613				ZINC13740951	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041682	COc1ccc(cc1C)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-16-12-19(9-11-21(16)29-2)26(28)20(13-17-6-4-3-5-7-17)24(25(27)32-26)18-8-10-22-23(14-18)31-15-30-22/h3-12,14,28H,13,15H2,1-2H3	WWMOPKHFPOIUHU-UHFFFAOYSA-N	50034270	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-3-methyl-phenyl)-5H-furan-2-one::CHEMBL10588	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034270&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10342643	103942471		CHEMBL10588				ZINC13740955	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041683	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(Cl)cc2)cc1	InChI=1S/C25H21ClO5/c1-29-20-11-3-16(4-12-20)15-22-23(17-5-9-19(26)10-6-17)24(27)31-25(22,28)18-7-13-21(30-2)14-8-18/h3-14,28H,15H2,1-2H3	RQUIHRSTPLMWSU-UHFFFAOYSA-N	50034254	3-(4-Chloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10648	Endothelin-1 receptor			 960							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034254&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9980487	103942455		CHEMBL10648				ZINC13740967	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041684	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc1	InChI=1S/C26H22O7/c1-29-19-8-3-16(4-9-19)13-21-24(17-5-12-22-23(14-17)32-15-31-22)25(27)33-26(21,28)18-6-10-20(30-2)11-7-18/h3-12,14,28H,13,15H2,1-2H3	SUKHVLAHDGZTPC-UHFFFAOYSA-N	50034259	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11115	Endothelin-1 receptor			 9							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034259&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9955200	103942460		CHEMBL11115				ZINC13740959	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041685	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C24H18O5/c25-23-22(17-11-12-20-21(14-17)28-15-27-20)19(13-16-7-3-1-4-8-16)24(26,29-23)18-9-5-2-6-10-18/h1-12,14,26H,13,15H2	SDCJODJPKKXXTB-UHFFFAOYSA-N	50034255	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-phenyl-5H-furan-2-one::CHEMBL11131	Endothelin-1 receptor			 1300							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034255&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			345351	103942456		CHEMBL11131				ZINC06574969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50041686	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(Cl)c(Cl)c2)cc1	InChI=1S/C25H20Cl2O5/c1-30-18-8-3-15(4-9-18)13-20-23(16-5-12-21(26)22(27)14-16)24(28)32-25(20,29)17-6-10-19(31-2)11-7-17/h3-12,14,29H,13H2,1-2H3	RYEVVTBWAHSOKY-UHFFFAOYSA-N	50034266	3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10996	Endothelin-1 receptor			 310							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10412464	103942467		CHEMBL10996				ZINC13740973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048810	CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](NC1=O)[C@@H](C)CC)C1c2ccccc2CCc2ccccc12	InChI=1S/C50H63N7O8/c1-7-28(5)42-48(63)54-38(24-32-26-51-36-20-14-13-17-33(32)36)46(61)57-44(41-34-18-11-9-15-30(34)21-22-31-16-10-12-19-35(31)41)50(65)53-37(23-27(3)4)45(60)52-39(25-40(58)59)47(62)55-43(29(6)8-2)49(64)56-42/h9-20,26-29,37-39,41-44,51H,7-8,21-25H2,1-6H3,(H,52,60)(H,53,65)(H,54,63)(H,55,62)(H,56,64)(H,57,61)(H,58,59)/t28-,29-,37-,38-,39+,42+,43-,44+/m0/s1	DXUYSEURVUTUAF-CYGLQZDSSA-N	50032167	CHEMBL2370246::[(2R,5S,8R,11S,17S)-5,8-Bis-((S)-sec-butyl)-14-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-11-(1H-indol-3-ylmethyl)-17-isobutyl-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16hexaaza-cyclooctadec-2-yl]-acetic acid	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032167&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73354540	103940717		CHEMBL2370246					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048811	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35-,36-,37-,38-,40-,41-/m0/s1	GNRBLKLDFZWDTC-RPEMCHKGSA-N	50032166	(S)-3-[(S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL317099	Endothelin-1 receptor			 910.0							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032166&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327853	103940716		CHEMBL317099					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048816	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N10O10/c1-6-28(3)41(46(66)58-38(49(69)70)25-33-27-54-35-22-15-14-21-34(33)35)60-47(67)42(29(4)7-2)59-45(65)37(26-39(62)63)57-44(64)36(23-16-24-53-50(51)52)56-48(68)43(55-30(5)61)40(31-17-10-8-11-18-31)32-19-12-9-13-20-32/h8-15,17-22,27-29,36-38,40-43,54H,6-7,16,23-26H2,1-5H3,(H,55,61)(H,56,68)(H,57,64)(H,58,66)(H,59,65)(H,60,67)(H,62,63)(H,69,70)(H4,51,52,53)/t28-,29-,36-,37-,38-,41-,42-,43-/m0/s1	YOMSYVFQYBPECD-TYTHOBKFSA-N	50032175	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-5-guanidino-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL405599	Endothelin-1 receptor			 4							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032175&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10463627	103940725		CHEMBL405599					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048828	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CC)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-8-30(6)43(48(64)55-39(51(67)68)26-34-28-52-36-24-18-17-23-35(34)36)58-49(65)44(31(7)9-2)57-47(63)38(27-41(60)61)53-46(62)37(25-29(4)5)54-50(66)45(56-40(59)10-3)42(32-19-13-11-14-20-32)33-21-15-12-16-22-33/h11-24,28-31,37-39,42-45,52H,8-10,25-27H2,1-7H3,(H,53,62)(H,54,66)(H,55,64)(H,56,59)(H,57,63)(H,58,65)(H,60,61)(H,67,68)/t30-,31-,37-,38-,39-,43-,44-,45-/m0/s1	ASPXCZHJJMKYNZ-LCHPGPOGSA-N	50032184	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-[(S)-2-((S)-3,3-diphenyl-2-propionylamino-propionylamino)-4-methyl-pentanoylamino]-succinamic acid::CHEMBL323331	Endothelin-1 receptor			 230							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032184&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327659	103940734		CHEMBL323331					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048831	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O	InChI=1S/C50H66N8O9/c1-8-29(5)42(48(65)54-37(45(51)62)25-34-27-52-36-23-17-16-22-35(34)36)58-49(66)43(30(6)9-2)57-47(64)39(26-40(60)61)55-46(63)38(24-28(3)4)56-50(67)44(53-31(7)59)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,52H,8-9,24-26H2,1-7H3,(H2,51,62)(H,53,59)(H,54,65)(H,55,63)(H,56,67)(H,57,64)(H,58,66)(H,60,61)/t29-,30-,37-,38-,39-,42-,43-,44-/m0/s1	OAUGIJWXGIUSTE-SRYIDKSASA-N	50032183	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL329609	Endothelin-1 receptor			 6000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032183&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327876	103940733		CHEMBL329609					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048832	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C1CCCCC1)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H73N7O10/c1-7-33(5)46(52(68)59-43(55(71)72)29-38-31-56-40-27-19-18-26-39(38)40)61-53(69)47(34(6)8-2)60-51(67)42(30-44(63)64)57-50(66)41(28-32(3)4)58-54(70)48(62-49(65)37-24-16-11-17-25-37)45(35-20-12-9-13-21-35)36-22-14-10-15-23-36/h9-10,12-15,18-23,26-27,31-34,37,41-43,45-48,56H,7-8,11,16-17,24-25,28-30H2,1-6H3,(H,57,66)(H,58,70)(H,59,68)(H,60,67)(H,61,69)(H,62,65)(H,63,64)(H,71,72)/t33-,34-,41-,42-,43-,46-,47-,48-/m0/s1	AOHDSQGONFMAPD-AXCZMTTCSA-N	50032185	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-2-[(S)-2-(cyclohexanecarbonyl-amino)-3,3-diphenyl-propionylamino]-4-methyl-pentanoylamino}-succinamic acid::CHEMBL414082	Endothelin-1 receptor			 6200							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032185&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327585	103940735		CHEMBL414082					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048837	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1ccccc1)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H67N7O10/c1-7-33(5)46(52(68)59-43(55(71)72)29-38-31-56-40-27-19-18-26-39(38)40)61-53(69)47(34(6)8-2)60-51(67)42(30-44(63)64)57-50(66)41(28-32(3)4)58-54(70)48(62-49(65)37-24-16-11-17-25-37)45(35-20-12-9-13-21-35)36-22-14-10-15-23-36/h9-27,31-34,41-43,45-48,56H,7-8,28-30H2,1-6H3,(H,57,66)(H,58,70)(H,59,68)(H,60,67)(H,61,69)(H,62,65)(H,63,64)(H,71,72)/t33-,34-,41-,42-,43-,46-,47-,48-/m0/s1	WLTGCYCLVZUDPF-AXCZMTTCSA-N	50032173	(S)-3-[(S)-2-((S)-2-Benzoylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL384052	Endothelin-1 receptor			 6300							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032173&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327890	103940723		CHEMBL384052					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048839	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(C)(C)C)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H71N7O10/c1-10-31(5)43(48(65)57-40(51(68)69)27-35-29-54-37-25-19-18-24-36(35)37)59-49(66)44(32(6)11-2)58-47(64)39(28-41(61)62)55-46(63)38(26-30(3)4)56-50(67)45(60-52(70)53(7,8)9)42(33-20-14-12-15-21-33)34-22-16-13-17-23-34/h12-25,29-32,38-40,42-45,54H,10-11,26-28H2,1-9H3,(H,55,63)(H,56,67)(H,57,65)(H,58,64)(H,59,66)(H,60,70)(H,61,62)(H,68,69)/t31-,32-,38-,39-,40-,43-,44-,45-/m0/s1	MJHWFSDVHUMVLT-FSTOQCHHSA-N	50032196	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-2-[(S)-2-(2,2-dimethyl-propionylamino)-3,3-diphenyl-propionylamino]-4-methyl-pentanoylamino}-succinamic acid::CHEMBL262229	Endothelin-1 receptor			 10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032196&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327466	103940746		CHEMBL262229					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048849	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NS(C)(=O)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O11S/c1-8-29(5)41(46(61)53-38(49(64)65)25-33-27-50-35-23-17-16-22-34(33)35)55-47(62)42(30(6)9-2)54-45(60)37(26-39(57)58)51-44(59)36(24-28(3)4)52-48(63)43(56-68(7,66)67)40(31-18-12-10-13-19-31)32-20-14-11-15-21-32/h10-23,27-30,36-38,40-43,50,56H,8-9,24-26H2,1-7H3,(H,51,59)(H,52,63)(H,53,61)(H,54,60)(H,55,62)(H,57,58)(H,64,65)/t29-,30-,36-,37-,38-,41-,42-,43-/m0/s1	XSVMSRFRFMDPSQ-MVMSJIHBSA-N	50032189	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-[(S)-2-((S)-2-methanesulfonylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-succinamic acid::CHEMBL96822	Endothelin-1 receptor			 2100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032189&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327628	103940739		CHEMBL96822					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048852	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O8/c1-8-30(5)42(47(61)54-41(49(63)64)27-35-28-50-37-23-17-16-22-36(35)37)56-48(62)43(31(6)9-2)55-46(60)40(26-34-20-14-11-15-21-34)53-44(58)38(24-29(3)4)52-45(59)39(51-32(7)57)25-33-18-12-10-13-19-33/h10-23,28-31,38-43,50H,8-9,24-27H2,1-7H3,(H,51,57)(H,52,59)(H,53,58)(H,54,61)(H,55,60)(H,56,62)(H,63,64)/t30-,31-,38-,39-,40-,41-,42-,43-/m0/s1	BQFWUVDRXODPBL-CJPBSESTSA-N	50032198	(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL421190	Endothelin-1 receptor			 36							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032198&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327629	103940748		CHEMBL421190					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048857	CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N8O10/c1-6-30(4)43(48(65)57-40(50(67)68)26-34-28-52-36-22-14-13-21-35(34)36)58-45(62)37(23-15-16-24-51)54-47(64)39(27-41(60)61)55-46(63)38(25-29(2)3)56-49(66)44(53-31(5)59)42(32-17-9-7-10-18-32)33-19-11-8-12-20-33/h7-14,17-22,28-30,37-40,42-44,52H,6,15-16,23-27,51H2,1-5H3,(H,53,59)(H,54,64)(H,55,63)(H,56,66)(H,57,65)(H,58,62)(H,60,61)(H,67,68)/t30-,37-,38-,39-,40-,43-,44-/m0/s1	ALWPEEGNMHILML-VVKSDJSFSA-N	50032199	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-5-amino-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-pentyl)-succinamic acid::CHEMBL94525	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032199&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328090	103940749		CHEMBL94525					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048860	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O10/c1-6-32(4)46(51(67)58-41(27-34-18-10-7-11-19-34)49(65)59-43(53(69)70)28-37-30-54-39-25-17-16-24-38(37)39)60-50(66)42(29-44(62)63)56-48(64)40(26-31(2)3)57-52(68)47(55-33(5)61)45(35-20-12-8-13-21-35)36-22-14-9-15-23-36/h7-25,30-32,40-43,45-47,54H,6,26-29H2,1-5H3,(H,55,61)(H,56,64)(H,57,68)(H,58,67)(H,59,65)(H,60,66)(H,62,63)(H,69,70)/t32-,40-,41-,42-,43-,46-,47-/m0/s1	YSXSBXCLZOAQIO-UJGVUKHOSA-N	50032204	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-phenyl-ethylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL405709	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032204&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327778	103940754		CHEMBL405709					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048861	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC12CC3CC(CC(C3)C1)C2)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C48H71N7O10/c1-8-26(5)40(45(62)53-37(47(64)65)18-32-24-49-34-13-11-10-12-33(32)34)55-46(63)41(27(6)9-2)54-43(60)36(19-39(57)58)52-42(59)35(14-25(3)4)51-44(61)38(50-28(7)56)23-48-20-29-15-30(21-48)17-31(16-29)22-48/h10-13,24-27,29-31,35-38,40-41,49H,8-9,14-23H2,1-7H3,(H,50,56)(H,51,61)(H,52,59)(H,53,62)(H,54,60)(H,55,63)(H,57,58)(H,64,65)/t26-,27-,29?,30?,31?,35-,36-,37-,38-,40-,41-,48?/m0/s1	QDBKZZOPRSHZDZ-AESGEIOASA-N	50032203	(S)-3-[(S)-2-((S)-2-Acetylamino-3-adamantan-1-yl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL327523	Endothelin-1 receptor			 3200							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032203&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327868	103940753		CHEMBL327523					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048863	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H69N7O9/c1-8-33(5)47(52(67)60-45(55(70)71)30-39-31-56-42-23-17-16-22-41(39)42)62-53(68)48(34(6)9-2)61-51(66)44(29-36-24-26-40(64)27-25-36)58-50(65)43(28-32(3)4)59-54(69)49(57-35(7)63)46(37-18-12-10-13-19-37)38-20-14-11-15-21-38/h10-27,31-34,43-49,56,64H,8-9,28-30H2,1-7H3,(H,57,63)(H,58,65)(H,59,69)(H,60,67)(H,61,66)(H,62,68)(H,70,71)/t33-,34-,43-,44-,45-,47-,48-,49-/m0/s1	OSMDQTQSIVHJQS-YRANRYISSA-N	50032201	(S)-2-((2S,3S)-2-{(2S,3S)-2-[(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-3-methyl-pentanoylamino)-3-(1H-indol-3-yl)-propionic acid::CHEMBL384728	Endothelin-1 receptor			 500							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032201&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327869	103940751		CHEMBL384728					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048865	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C54H67N7O9/c1-7-33(5)45(50(66)59-43(53(69)70)29-35-31-56-40-27-19-18-26-39(35)40)61-51(67)46(34(6)8-2)60-49(65)42(30-44(62)63)57-48(64)41(28-32(3)4)58-52(68)47(55)54(36-20-12-9-13-21-36,37-22-14-10-15-23-37)38-24-16-11-17-25-38/h9-27,31-34,41-43,45-47,56H,7-8,28-30,55H2,1-6H3,(H,57,64)(H,58,68)(H,59,66)(H,60,65)(H,61,67)(H,62,63)(H,69,70)/t33-,34-,41-,42-,43-,45-,46-,47+/m0/s1	DQBRWELOCHMKTC-MHYLPQDBSA-N	50032206	(S)-3-[(S)-2-((S)-2-Amino-3,3,3-triphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL269428	Endothelin-1 receptor			 11000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032206&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327867	103940756		CHEMBL269428					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048871	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-30(6)43(48(64)54-38(24-29(4)5)46(62)56-40(50(66)67)25-34-27-51-36-22-16-15-21-35(34)36)57-47(63)39(26-41(59)60)53-45(61)37(23-28(2)3)55-49(65)44(52-31(7)58)42(32-17-11-9-12-18-32)33-19-13-10-14-20-33/h9-22,27-30,37-40,42-44,51H,8,23-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,64)(H,55,65)(H,56,62)(H,57,63)(H,59,60)(H,66,67)/t30-,37-,38-,39-,40-,43-,44-/m0/s1	PPBOBEGAVCYYSB-VVKSDJSFSA-N	50032174	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL97431	Endothelin-1 receptor			 340							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032174&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328042	103940724		CHEMBL97431					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048876	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H63N7O10/c1-8-29(6)42(47(63)54-38(49(65)66)24-33-26-50-35-22-16-15-21-34(33)35)56-46(62)41(28(4)5)55-45(61)37(25-39(58)59)52-44(60)36(23-27(2)3)53-48(64)43(51-30(7)57)40(31-17-11-9-12-18-31)32-19-13-10-14-20-32/h9-22,26-29,36-38,40-43,50H,8,23-25H2,1-7H3,(H,51,57)(H,52,60)(H,53,64)(H,54,63)(H,55,61)(H,56,62)(H,58,59)(H,65,66)/t29-,36-,37-,38-,41-,42-,43-/m0/s1	DRQGVADKIBRYTL-KNTSQTEZSA-N	50032207	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-propyl)-succinamic acid::CHEMBL319660	Endothelin-1 receptor			 29							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032207&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327892	103940757		CHEMBL319660					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048879	CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H61N7O12/c1-6-28(4)42(47(65)55-38(49(67)68)24-32-26-50-34-20-14-13-19-33(32)34)56-44(62)35(21-22-39(58)59)52-46(64)37(25-40(60)61)53-45(63)36(23-27(2)3)54-48(66)43(51-29(5)57)41(30-15-9-7-10-16-30)31-17-11-8-12-18-31/h7-20,26-28,35-38,41-43,50H,6,21-25H2,1-5H3,(H,51,57)(H,52,64)(H,53,63)(H,54,66)(H,55,65)(H,56,62)(H,58,59)(H,60,61)(H,67,68)/t28-,35-,36-,37-,38-,42-,43-/m0/s1	HTKJJFQSPQJMIW-NUFMZFPJSA-N	50032176	(S)-4-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-carboxy-propionylamino}-4-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-butyric acid::CHEMBL318020	Endothelin-1 receptor			 450							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032176&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328091	103940726		CHEMBL318020					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048882	CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](NC1=O)[C@@H](C)CC	InChI=1S/C42H57N7O8/c1-7-24(5)35-41(56)47-32(20-27-22-43-29-17-13-12-16-28(27)29)39(54)45-31(19-26-14-10-9-11-15-26)38(53)44-30(18-23(3)4)37(52)46-33(21-34(50)51)40(55)48-36(25(6)8-2)42(57)49-35/h9-17,22-25,30-33,35-36,43H,7-8,18-21H2,1-6H3,(H,44,53)(H,45,54)(H,46,52)(H,47,56)(H,48,55)(H,49,57)(H,50,51)/t24-,25-,30-,31+,32-,33+,35+,36-/m0/s1	KBMAGHTWYBOHDY-WADKQMKDSA-N	50032188	CHEMBL94730::[(2R,5S,8R,11S,14R,17S)-14-Benzyl-5,8-bis-((S)-sec-butyl)-11-(1H-indol-3-ylmethyl)-17-isobutyl-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16hexaaza-cyclooctadec-2-yl]-acetic acid	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032188&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327875	103940738		CHEMBL94730				ZINC95540456	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048886	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)c1cccnc1)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C54H66N8O10/c1-7-32(5)45(51(68)59-42(54(71)72)27-37-30-56-39-24-16-15-23-38(37)39)61-52(69)46(33(6)8-2)60-50(67)41(28-43(63)64)57-49(66)40(26-31(3)4)58-53(70)47(62-48(65)36-22-17-25-55-29-36)44(34-18-11-9-12-19-34)35-20-13-10-14-21-35/h9-25,29-33,40-42,44-47,56H,7-8,26-28H2,1-6H3,(H,57,66)(H,58,70)(H,59,68)(H,60,67)(H,61,69)(H,62,65)(H,63,64)(H,71,72)/t32-,33-,40-,41-,42-,45-,46-,47-/m0/s1	MYTOIXPAVZUEEF-AIXQDFFPSA-N	50032214	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-((S)-2-{(S)-3,3-diphenyl-2-[(pyridine-3-carbonyl)-amino]-propionylamino}-4-methyl-pentanoylamino)-succinamic acid::CHEMBL265734	Endothelin-1 receptor			 5000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032214&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328057	103940764		CHEMBL265734					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048888	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C1c2ccccc2CCc2ccccc12)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C64H75N7O10/c1-7-38(5)55(61(77)68-51(64(80)81)34-44-36-65-48-30-20-19-27-45(44)48)70-62(78)56(39(6)8-2)69-59(75)50(35-52(72)73)66-58(74)49(33-37(3)4)67-63(79)57(53(42-23-11-9-12-24-42)43-25-13-10-14-26-43)71-60(76)54-46-28-17-15-21-40(46)31-32-41-22-16-18-29-47(41)54/h9-30,36-39,49-51,53-57,65H,7-8,31-35H2,1-6H3,(H,66,74)(H,67,79)(H,68,77)(H,69,75)(H,70,78)(H,71,76)(H,72,73)(H,80,81)/t38-,39-,49-,50-,51-,55-,56-,57-/m0/s1	YCMKLWNLPQHUNK-AUFHHPMTSA-N	50032177	CHEMBL264579::N-(1-{1-[1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-(2-{2-[(10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-carbonyl)-amino]-3,3-diphenyl-propionylamino}-4-methyl-pentanoylamino)-succinamic acid	Endothelin-1 receptor			 3600							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032177&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327347	103940727		CHEMBL264579					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048890	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-7-27(4)40(45(61)53-37(47(63)64)23-32-25-48-34-21-15-14-20-33(32)34)54-42(58)28(5)49-43(59)36(24-38(56)57)51-44(60)35(22-26(2)3)52-46(62)41(50-29(6)55)39(30-16-10-8-11-17-30)31-18-12-9-13-19-31/h8-21,25-28,35-37,39-41,48H,7,22-24H2,1-6H3,(H,49,59)(H,50,55)(H,51,60)(H,52,62)(H,53,61)(H,54,58)(H,56,57)(H,63,64)/t27-,28-,35-,36-,37-,40-,41-/m0/s1	LHABXBWIIYUERU-WJEZPDPISA-N	50032186	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-ethyl)-succinamic acid::CHEMBL94907	Endothelin-1 receptor			 420							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032186&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327870	103940736		CHEMBL94907					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048891	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)NC)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N8O10/c1-8-29(5)41(46(63)55-38(49(66)67)25-33-27-52-35-23-17-16-22-34(33)35)57-47(64)42(30(6)9-2)56-45(62)37(26-39(59)60)53-44(61)36(24-28(3)4)54-48(65)43(58-50(68)51-7)40(31-18-12-10-13-19-31)32-20-14-11-15-21-32/h10-23,27-30,36-38,40-43,52H,8-9,24-26H2,1-7H3,(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)(H2,51,58,68)/t29-,30-,36-,37-,38-,41-,42-,43-/m0/s1	PIENNYPWHMRMAZ-MVMSJIHBSA-N	50032178	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-4-methyl-2-[(S)-2-(3-methyl-ureido)-3,3-diphenyl-propionylamino]-pentanoylamino}-succinamic acid::CHEMBL433406	Endothelin-1 receptor			 850.0							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032178&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327821	103940728		CHEMBL433406					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048892	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O8/c1-9-29(5)41(46(60)54-39(49(63)64)26-35-27-50-37-24-18-17-23-36(35)37)56-47(61)42(30(6)10-2)55-44(58)31(7)51-45(59)38(25-28(3)4)53-48(62)43(52-32(8)57)40(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,27-31,38-43,50H,9-10,25-26H2,1-8H3,(H,51,59)(H,52,57)(H,53,62)(H,54,60)(H,55,58)(H,56,61)(H,63,64)/t29-,30-,31-,38-,39-,41-,42-,43-/m0/s1	NKXZGLUBJIDNGG-BSUGJTRNSA-N	50032202	(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL319719	Endothelin-1 receptor			 70.0							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328092	103940752		CHEMBL319719					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048894	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1cccnc1)C(O)=O	InChI=1S/C47H63N7O10/c1-8-28(5)39(44(60)52-36(47(63)64)24-31-17-16-22-48-26-31)54-45(61)40(29(6)9-2)53-43(59)35(25-37(56)57)50-42(58)34(23-27(3)4)51-46(62)41(49-30(7)55)38(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-22,26-29,34-36,38-41H,8-9,23-25H2,1-7H3,(H,49,55)(H,50,58)(H,51,62)(H,52,60)(H,53,59)(H,54,61)(H,56,57)(H,63,64)/t28-,29-,34-,35-,36-,39-,40-,41-/m0/s1	RJRATOSPCIEAAM-UCARNMNASA-N	50032211	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(1S,2S)-1-[(1S,2S)-1-(1-carboxy-2-pyridin-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::CHEMBL2370252	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032211	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032211&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73354541	103940761		CHEMBL2370252					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048895	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)CCC(O)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C52H67N7O12/c1-7-30(5)44(49(67)56-39(52(70)71)26-34-28-53-36-22-16-15-21-35(34)36)59-50(68)45(31(6)8-2)58-48(66)38(27-42(63)64)54-47(65)37(25-29(3)4)55-51(69)46(57-40(60)23-24-41(61)62)43(32-17-11-9-12-18-32)33-19-13-10-14-20-33/h9-22,28-31,37-39,43-46,53H,7-8,23-27H2,1-6H3,(H,54,65)(H,55,69)(H,56,67)(H,57,60)(H,58,66)(H,59,68)(H,61,62)(H,63,64)(H,70,71)/t30-,31-,37-,38-,39-,44-,45-,46-/m0/s1	MAAGLNWCCDGAHA-RRQXNUCCSA-N	50032200	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-2-[(S)-2-(3-carboxy-propionylamino)-3,3-diphenyl-propionylamino]-4-methyl-pentanoylamino}-succinamic acid::CHEMBL439435	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032200&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328073	103940750		CHEMBL439435					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048901	CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](NC1=O)[C@@H](C)CC)C(c1ccccc1)c1ccccc1	InChI=1S/C48H61N7O8/c1-7-28(5)40-46(61)52-36(24-32-26-49-34-22-16-15-21-33(32)34)44(59)55-42(39(30-17-11-9-12-18-30)31-19-13-10-14-20-31)48(63)51-35(23-27(3)4)43(58)50-37(25-38(56)57)45(60)53-41(29(6)8-2)47(62)54-40/h9-22,26-29,35-37,39-42,49H,7-8,23-25H2,1-6H3,(H,50,58)(H,51,63)(H,52,61)(H,53,60)(H,54,62)(H,55,59)(H,56,57)/t28-,29-,35-,36-,37+,40+,41-,42+/m0/s1	SBZRTRGTNMXEJF-UIWRFEIXSA-N	50032194	CHEMBL2370247::[(2R,5S,8R,11S,17S)-14-Benzhydryl-5,8-bis-((S)-sec-butyl)-11-(1H-indol-3-ylmethyl)-17-isobutyl-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16hexaaza-cyclooctadec-2-yl]-acetic acid	Endothelin-1 receptor			 7100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032194&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73348480	103940744		CHEMBL2370247					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048902	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C56H69N7O10/c1-8-34(5)47(52(69)61-45(55(72)73)30-37-32-57-42-28-20-19-27-41(37)42)63-53(70)48(35(6)9-2)62-51(68)44(31-46(65)66)59-50(67)43(29-33(3)4)60-54(71)49(58-36(7)64)56(38-21-13-10-14-22-38,39-23-15-11-16-24-39)40-25-17-12-18-26-40/h10-28,32-35,43-45,47-49,57H,8-9,29-31H2,1-7H3,(H,58,64)(H,59,67)(H,60,71)(H,61,69)(H,62,68)(H,63,70)(H,65,66)(H,72,73)/t34-,35-,43-,44-,45-,47-,48-,49+/m0/s1	DWRSIXNLCWVMLR-GAQYKUSUSA-N	50032168	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3,3-triphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL405178	Endothelin-1 receptor			 2600							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032168&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328019	103940718		CHEMBL405178					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048903	CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-8-30(5)43(48(64)56-40(51(67)68)27-35-28-52-37-23-17-16-22-36(35)37)58-49(65)44(31(6)9-2)57-46(62)38(24-25-41(60)61)54-47(63)39(26-29(3)4)55-50(66)45(53-32(7)59)42(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,28-31,38-40,42-45,52H,8-9,24-27H2,1-7H3,(H,53,59)(H,54,63)(H,55,66)(H,56,64)(H,57,62)(H,58,65)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	WXIDXBSXUCQMKX-KUIIPSLPSA-N	50032191	(S)-4-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-4-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butylcarbamoyl)-butyric acid::CHEMBL433349	Endothelin-1 receptor			 21							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032191&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328089	103940741		CHEMBL433349					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048906	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c(C)c(C)c(C)c(C)c1C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H69N7O9/c1-12-24(5)40(45(60)52-38(47(62)63)19-31-22-49-35-17-15-14-16-32(31)35)54-46(61)41(25(6)13-2)53-44(59)37(21-39(55)56)51-43(58)36(18-23(3)4)50-42(57)34(48)20-33-29(10)27(8)26(7)28(9)30(33)11/h14-17,22-25,34,36-38,40-41,49H,12-13,18-21,48H2,1-11H3,(H,50,57)(H,51,58)(H,52,60)(H,53,59)(H,54,61)(H,55,56)(H,62,63)/t24-,25-,34-,36-,37-,38-,40-,41-/m0/s1	LATVCTHHUFKLSE-ZOEARCMYSA-N	50032182	(S)-3-[(S)-2-((S)-2-Amino-3-pentamethylphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL327590	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032182&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327889	103940732		CHEMBL327590					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048907	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O	InChI=1S/C48H64N6O11/c1-8-28(5)40(45(61)52-37(48(64)65)25-31-20-22-34(56)23-21-31)54-46(62)41(29(6)9-2)53-44(60)36(26-38(57)58)50-43(59)35(24-27(3)4)51-47(63)42(49-30(7)55)39(32-16-12-10-13-17-32)33-18-14-11-15-19-33/h10-23,27-29,35-37,39-42,56H,8-9,24-26H2,1-7H3,(H,49,55)(H,50,59)(H,51,63)(H,52,61)(H,53,60)(H,54,62)(H,57,58)(H,64,65)/t28-,29-,35-,36-,37-,40-,41-,42-/m0/s1	QXIDYPVHAGHZKK-SVTGUICBSA-N	50032210	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[1-carboxy-2-(4-hydroxy-phenyl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL2370254	Endothelin-1 receptor			 6100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032210&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73348481	103940760		CHEMBL2370254					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50045639	CCCCN(CCCC)C(=O)CN1CC(C(C1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)	MOTJMGVDPWRKOC-UHFFFAOYSA-N	50050976	4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL8923	Endothelin-1 receptor		 0.069000								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050976&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9914310	103948067		CHEMBL8923				ZINC34026477	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048912	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H61N7O12/c1-6-28(4)42(47(65)52-35(21-22-39(58)59)44(62)55-38(49(67)68)24-32-26-50-34-20-14-13-19-33(32)34)56-46(64)37(25-40(60)61)53-45(63)36(23-27(2)3)54-48(66)43(51-29(5)57)41(30-15-9-7-10-16-30)31-17-11-8-12-18-31/h7-20,26-28,35-38,41-43,50H,6,21-25H2,1-5H3,(H,51,57)(H,52,65)(H,53,63)(H,54,66)(H,55,62)(H,56,64)(H,58,59)(H,60,61)(H,67,68)/t28-,35-,36-,37-,38-,42-,43-/m0/s1	CSHJCRKHBQNUTR-NUFMZFPJSA-N	50032215	(S)-4-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-carboxy-propionylamino}-3-methyl-pentanoylamino)-4-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-butyric acid::CHEMBL329170	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032215&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327931	103940765		CHEMBL329170					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048914	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O11/c1-6-31(4)46(51(68)59-43(53(70)71)27-36-29-54-39-20-14-13-19-38(36)39)60-50(67)41(26-33-21-23-37(62)24-22-33)56-49(66)42(28-44(63)64)57-48(65)40(25-30(2)3)58-52(69)47(55-32(5)61)45(34-15-9-7-10-16-34)35-17-11-8-12-18-35/h7-24,29-31,40-43,45-47,54,62H,6,25-28H2,1-5H3,(H,55,61)(H,56,66)(H,57,65)(H,58,69)(H,59,68)(H,60,67)(H,63,64)(H,70,71)/t31-,40-,41-,42-,43-,46-,47-/m0/s1	JBDVSJVBSKTZJR-GNQVYTNOSA-N	50032216	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-[(S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-(4-hydroxy-phenyl)-ethyl]-succinamic acid::CHEMBL385492	Endothelin-1 receptor			 68.0							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032216&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327902	103940766		CHEMBL385492					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048915	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C12CC3CC(CC(C3)C1)C2)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C59H77N7O10/c1-7-34(5)49(54(71)63-46(57(74)75)27-41-32-60-43-22-16-15-21-42(41)43)65-55(72)50(35(6)8-2)64-53(70)45(28-47(67)68)61-52(69)44(23-33(3)4)62-56(73)51(48(39-17-11-9-12-18-39)40-19-13-10-14-20-40)66-58(76)59-29-36-24-37(30-59)26-38(25-36)31-59/h9-22,32-38,44-46,48-51,60H,7-8,23-31H2,1-6H3,(H,61,69)(H,62,73)(H,63,71)(H,64,70)(H,65,72)(H,66,76)(H,67,68)(H,74,75)/t34-,35-,36?,37?,38?,44-,45-,46-,49-,50-,51-,59?/m0/s1	VEAQFGVEFHRRAQ-FOVRPUPFSA-N	50032192	3-(2-{2-[(Adamantane-1-carbonyl)-amino]-3,3-diphenyl-propionylamino}-4-methyl-pentanoylamino)-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL413179	Endothelin-1 receptor			 3500							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032192&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327881	103940742		CHEMBL413179					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048918	CC[C@H](C)[C@@H]1NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1	InChI=1S/C44H51N7O10S2/c1-4-24(2)37-42(58)49-34(41(57)48-32(44(60)61)19-28-21-45-30-18-12-11-17-29(28)30)23-63-62-22-33(40(56)47-31(20-35(53)54)39(55)51-37)50-43(59)38(46-25(3)52)36(26-13-7-5-8-14-26)27-15-9-6-10-16-27/h5-18,21,24,31-34,36-38,45H,4,19-20,22-23H2,1-3H3,(H,46,52)(H,47,56)(H,48,57)(H,49,58)(H,50,59)(H,51,55)(H,53,54)(H,60,61)/t24-,31+,32-,33+,34-,37-,38+/m0/s1	DLTKIIYVGQMDMK-HKVTWNDMSA-N	50032187	(S)-2-{[(4R,7S,10R,13S)-13-(2-Acetylamino-3,3-diphenyl-propionylamino)-7-((S)-sec-butyl)-10-carboxymethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carbonyl]-amino}-3-(1H-indol-3-yl)-propionic acid::CHEMBL2370245	Endothelin-1 receptor			>1000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73350066	103940737		CHEMBL2370245					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048919	CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C52H72N8O8/c1-8-32(5)44(49(64)58-42(52(67)68)29-37-30-54-39-25-17-16-24-38(37)39)60-50(65)45(33(6)9-2)59-47(62)40(26-18-19-27-53)56-48(63)41(28-31(3)4)57-51(66)46(55-34(7)61)43(35-20-12-10-13-21-35)36-22-14-11-15-23-36/h10-17,20-25,30-33,40-46,54H,8-9,18-19,26-29,53H2,1-7H3,(H,55,61)(H,56,63)(H,57,66)(H,58,64)(H,59,62)(H,60,65)(H,67,68)/t32-,33-,40-,41-,42-,44-,45-,46+/m0/s1	WGLAFABBGWXLCX-LGNPPWGXSA-N	50032205	(S)-2-[(2S,3S)-2-((2S,3S)-2-{2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-6-amino-hexanoylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL2370255	Endothelin-1 receptor			 430							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032205&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10102342	103940755		CHEMBL2370255					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048921	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H61N7O12/c1-6-27(3)41(46(64)54-37(49(67)68)24-32-26-50-34-21-15-14-20-33(32)34)56-47(65)42(28(4)7-2)55-45(63)36(25-39(60)61)53-44(62)35(22-23-38(58)59)52-48(66)43(51-29(5)57)40(30-16-10-8-11-17-30)31-18-12-9-13-19-31/h8-21,26-28,35-37,40-43,50H,6-7,22-25H2,1-5H3,(H,51,57)(H,52,66)(H,53,62)(H,54,64)(H,55,63)(H,56,65)(H,58,59)(H,60,61)(H,67,68)/t27-,28-,35-,36-,37-,41-,42-,43-/m0/s1	OVTDDVGHCAWGJB-CVEDHXPHSA-N	50032171	(S)-4-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-[(S)-2-carboxy-1-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butylcarbamoyl)-ethylcarbamoyl]-butyric acid::CHEMBL97470	Endothelin-1 receptor			 130							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032171&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327438	103940721		CHEMBL97470					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048922	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(F)(F)F)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H62F3N7O10/c1-7-28(5)40(45(65)57-37(48(68)69)24-32-26-54-34-22-16-15-21-33(32)34)59-46(66)41(29(6)8-2)58-44(64)36(25-38(61)62)55-43(63)35(23-27(3)4)56-47(67)42(60-49(70)50(51,52)53)39(30-17-11-9-12-18-30)31-19-13-10-14-20-31/h9-22,26-29,35-37,39-42,54H,7-8,23-25H2,1-6H3,(H,55,63)(H,56,67)(H,57,65)(H,58,64)(H,59,66)(H,60,70)(H,61,62)(H,68,69)/t28-,29-,35-,36-,37-,40-,41-,42-/m0/s1	QCRZVRDNUAFXCL-SVTGUICBSA-N	50032212	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-2-[(S)-3,3-diphenyl-2-(2,2,2-trifluoro-acetylamino)-propionylamino]-4-methyl-pentanoylamino}-succinamic acid::CHEMBL386181	Endothelin-1 receptor			 250							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032212&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327656	103940762		CHEMBL386181					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048923	CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H69N7O10/c1-6-32(4)46(51(67)59-43(53(69)70)28-37-30-54-39-25-17-16-24-38(37)39)60-50(66)41(27-34-18-10-7-11-19-34)56-49(65)42(29-44(62)63)57-48(64)40(26-31(2)3)58-52(68)47(55-33(5)61)45(35-20-12-8-13-21-35)36-22-14-9-15-23-36/h8-9,12-17,20-25,30-32,34,40-43,45-47,54H,6-7,10-11,18-19,26-29H2,1-5H3,(H,55,61)(H,56,65)(H,57,64)(H,58,68)(H,59,67)(H,60,66)(H,62,63)(H,69,70)/t32-,40-,41-,42-,43-,46-,47-/m0/s1	JIWCCEBFSJAHKC-UJGVUKHOSA-N	50032190	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-cyclohexyl-ethyl)-succinamic acid::CHEMBL263295	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032190&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327891	103940740		CHEMBL263295					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048924	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)NC1CCCCC1)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H74N8O10/c1-7-33(5)46(51(68)60-43(54(71)72)29-37-31-56-40-27-19-18-26-39(37)40)62-52(69)47(34(6)8-2)61-50(67)42(30-44(64)65)58-49(66)41(28-32(3)4)59-53(70)48(63-55(73)57-38-24-16-11-17-25-38)45(35-20-12-9-13-21-35)36-22-14-10-15-23-36/h9-10,12-15,18-23,26-27,31-34,38,41-43,45-48,56H,7-8,11,16-17,24-25,28-30H2,1-6H3,(H,58,66)(H,59,70)(H,60,68)(H,61,67)(H,62,69)(H,64,65)(H,71,72)(H2,57,63,73)/t33-,34-,41-,42-,43-,46-,47-,48-/m0/s1	TYJJYPAPTYMSSO-AXCZMTTCSA-N	50032209	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-{(S)-2-[(S)-2-(3-cyclohexyl-ureido)-3,3-diphenyl-propionylamino]-4-methyl-pentanoylamino}-succinamic acid::CHEMBL407933	Endothelin-1 receptor			 2000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032209	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032209&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327568	103940759		CHEMBL407933					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048925	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H64N8O10/c1-6-28(3)41(46(63)55-38(49(66)67)25-33-27-51-35-22-15-14-21-34(33)35)57-47(64)42(29(4)7-2)56-45(62)37(26-39(59)60)54-44(61)36(23-16-24-50)53-48(65)43(52-30(5)58)40(31-17-10-8-11-18-31)32-19-12-9-13-20-32/h8-15,17-22,27-29,36-38,40-43,51H,6-7,16,23-26,50H2,1-5H3,(H,52,58)(H,53,65)(H,54,61)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t28-,29-,36-,37-,38-,41-,42-,43-/m0/s1	IEJDKICPBODJMQ-TYTHOBKFSA-N	50032193	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-5-amino-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL94983	Endothelin-1 receptor			 30							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032193&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327437	103940743		CHEMBL94983					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048932	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O10/c1-6-31(3)45(50(66)58-42(53(69)70)28-37-30-54-39-26-18-17-25-38(37)39)60-51(67)46(32(4)7-2)59-49(65)41(29-43(62)63)56-48(64)40(27-34-19-11-8-12-20-34)57-52(68)47(55-33(5)61)44(35-21-13-9-14-22-35)36-23-15-10-16-24-36/h8-26,30-32,40-42,44-47,54H,6-7,27-29H2,1-5H3,(H,55,61)(H,56,64)(H,57,68)(H,58,66)(H,59,65)(H,60,67)(H,62,63)(H,69,70)/t31-,32-,40+,41-,42-,45-,46-,47-/m0/s1	HZVYDMKAAHZAMV-LJDWDNFTSA-N	50032170	(S)-3-[(R)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-3-phenyl-propionylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL411797	Endothelin-1 receptor			 380							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032170&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328018	103940720		CHEMBL411797					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048933	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C62H73N7O10/c1-7-38(5)53(59(75)66-49(62(78)79)34-44-36-63-46-32-22-21-31-45(44)46)68-60(76)54(39(6)8-2)67-57(73)48(35-50(70)71)64-56(72)47(33-37(3)4)65-61(77)55(51(40-23-13-9-14-24-40)41-25-15-10-16-26-41)69-58(74)52(42-27-17-11-18-28-42)43-29-19-12-20-30-43/h9-32,36-39,47-49,51-55,63H,7-8,33-35H2,1-6H3,(H,64,72)(H,65,77)(H,66,75)(H,67,73)(H,68,76)(H,69,74)(H,70,71)(H,78,79)/t38-,39-,47-,48-,49-,53-,54-,55-/m0/s1	MGBWTRZYKAIUGT-UEAASAEHSA-N	50032179	(S)-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-Carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-3-[(S)-2-((S)-2-diphenylacetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-succinamic acid::CHEMBL415238	Endothelin-1 receptor			 2600							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032179&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327348	103940729		CHEMBL415238					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048934	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30-,37-,38-,39-,42-,43-,44-/m0/s1	XUMJJSAQQCTKAO-SRYIDKSASA-N	50032172	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL328942	Endothelin-1 receptor			 40							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032172&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9897720	103940722		CHEMBL328942					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048936	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C1c2ccccc2CCc2ccccc12)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C52H67N7O10/c1-8-29(5)44(49(65)57-41(52(68)69)25-34-27-53-38-21-15-14-18-35(34)38)59-50(66)45(30(6)9-2)58-48(64)40(26-42(61)62)55-47(63)39(24-28(3)4)56-51(67)46(54-31(7)60)43-36-19-12-10-16-32(36)22-23-33-17-11-13-20-37(33)43/h10-21,27-30,39-41,43-46,53H,8-9,22-26H2,1-7H3,(H,54,60)(H,55,63)(H,56,67)(H,57,65)(H,58,64)(H,59,66)(H,61,62)(H,68,69)/t29-,30-,39-,40-,41-,44-,45-,46-/m0/s1	HRAQSWKGRRUBDJ-FFEQYNEASA-N	50032181	2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl(methylcarboxamido)methylcarboxamido]-3-methylbutylcarboxamido}ethylcarboxamido)-2-methylbutylcarboxamido]-2-methylbutylcarboxamido}-3-(1H-3-indolyl)propanoic acid::3-{2-[2-Acetylamino-2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-acetylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL262993	Endothelin-1 receptor			 4.9							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032181&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44304492	103940731		CHEMBL262993					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048944	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H63N7O10/c1-6-32(4)46(51(67)59-43(53(69)70)28-37-30-54-39-25-17-16-24-38(37)39)60-50(66)41(27-34-18-10-7-11-19-34)56-49(65)42(29-44(62)63)57-48(64)40(26-31(2)3)58-52(68)47(55-33(5)61)45(35-20-12-8-13-21-35)36-22-14-9-15-23-36/h7-25,30-32,40-43,45-47,54H,6,26-29H2,1-5H3,(H,55,61)(H,56,65)(H,57,64)(H,58,68)(H,59,67)(H,60,66)(H,62,63)(H,69,70)/t32-,40-,41-,42-,43-,46-,47-/m0/s1	BMROGBGRQLVZIB-UJGVUKHOSA-N	50032208	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-phenyl-ethyl)-succinamic acid::CHEMBL265116	Endothelin-1 receptor			 160							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032208&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327903	103940758		CHEMBL265116					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048945	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(O)=O	InChI=1S/C48H64N6O10/c1-8-29(5)40(45(60)52-37(48(63)64)26-32-19-13-10-14-20-32)54-46(61)41(30(6)9-2)53-44(59)36(27-38(56)57)50-43(58)35(25-28(3)4)51-47(62)42(49-31(7)55)39(33-21-15-11-16-22-33)34-23-17-12-18-24-34/h10-24,28-30,35-37,39-42H,8-9,25-27H2,1-7H3,(H,49,55)(H,50,58)(H,51,62)(H,52,60)(H,53,59)(H,54,61)(H,56,57)(H,63,64)/t29-,30-,35-,36-,37-,40-,41-,42-/m0/s1	KSOJBBDKSAOOMV-ZHTTVDOBSA-N	50032217	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(1S,2S)-1-[(1S,2S)-1-(1-carboxy-2-phenyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::CHEMBL2370253	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032217&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73345452	103940767		CHEMBL2370253					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048946	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H63N7O10/c1-8-29(6)42(47(63)55-41(28(4)5)46(62)54-38(49(65)66)24-33-26-50-35-22-16-15-21-34(33)35)56-45(61)37(25-39(58)59)52-44(60)36(23-27(2)3)53-48(64)43(51-30(7)57)40(31-17-11-9-12-18-31)32-19-13-10-14-20-32/h9-22,26-29,36-38,40-43,50H,8,23-25H2,1-7H3,(H,51,57)(H,52,60)(H,53,64)(H,54,62)(H,55,63)(H,56,61)(H,58,59)(H,65,66)/t29-,36-,37-,38-,41-,42-,43-/m0/s1	RVWZNRWHSOBHCH-KNTSQTEZSA-N	50032195	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL330144	Endothelin-1 receptor			 140							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032195&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328060	103940745		CHEMBL330144					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048947	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C48H63N7O9/c1-7-28(5)41(46(61)53-37(48(63)64)24-32-26-50-34-22-16-15-21-33(32)34)55-47(62)42(29(6)8-2)54-44(59)36(25-38(56)57)51-43(58)35(23-27(3)4)52-45(60)40(49)39(30-17-11-9-12-18-30)31-19-13-10-14-20-31/h9-22,26-29,35-37,39-42,50H,7-8,23-25,49H2,1-6H3,(H,51,58)(H,52,60)(H,53,61)(H,54,59)(H,55,62)(H,56,57)(H,63,64)/t28-,29-,35-,36-,37-,40-,41-,42-/m0/s1	UFEOKDZSHDFLTG-SVTGUICBSA-N	50032197	(S)-3-[(S)-2-((S)-2-Amino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL319537	Endothelin-1 receptor			 1900							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032197&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327660	103940747		CHEMBL319537					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048950	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H66N8O10/c1-6-30(4)43(48(65)54-37(23-15-16-24-51)45(62)57-40(50(67)68)26-34-28-52-36-22-14-13-21-35(34)36)58-47(64)39(27-41(60)61)55-46(63)38(25-29(2)3)56-49(66)44(53-31(5)59)42(32-17-9-7-10-18-32)33-19-11-8-12-20-33/h7-14,17-22,28-30,37-40,42-44,52H,6,15-16,23-27,51H2,1-5H3,(H,53,59)(H,54,65)(H,55,63)(H,56,66)(H,57,62)(H,58,64)(H,60,61)(H,67,68)/t30-,37-,38-,39-,40-,43-,44-/m0/s1	IKSOLGRXWOFPDB-VVKSDJSFSA-N	50032169	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(S)-5-amino-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-pentylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL431433	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032169&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44327779	103940719		CHEMBL431433					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048961	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c(C)c(C)c(C)c(C)c1C)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H71N7O10/c1-13-25(5)42(47(63)54-40(49(65)66)20-33-23-50-36-18-16-15-17-34(33)36)56-48(64)43(26(6)14-2)55-46(62)39(22-41(58)59)53-44(60)37(19-24(3)4)52-45(61)38(51-32(12)57)21-35-30(10)28(8)27(7)29(9)31(35)11/h15-18,23-26,37-40,42-43,50H,13-14,19-22H2,1-12H3,(H,51,57)(H,52,61)(H,53,60)(H,54,63)(H,55,62)(H,56,64)(H,58,59)(H,65,66)/t25-,26-,37-,38+,39-,40-,42-,43-/m0/s1	REJULBLUQJYXRX-DEBWCNEESA-N	50032213	(S)-3-[(S)-2-((R)-2-Acetylamino-3-pentamethylphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL94689	Endothelin-1 receptor			 1100							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032213&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10440821	103940763		CHEMBL94689					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048964	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H69N7O8/c1-8-34(5)47(52(66)60-45(55(69)70)31-40-32-56-42-28-20-19-27-41(40)42)62-53(67)48(35(6)9-2)61-51(65)44(30-37-21-13-10-14-22-37)58-50(64)43(29-33(3)4)59-54(68)49(57-36(7)63)46(38-23-15-11-16-24-38)39-25-17-12-18-26-39/h10-28,32-35,43-49,56H,8-9,29-31H2,1-7H3,(H,57,63)(H,58,64)(H,59,68)(H,60,66)(H,61,65)(H,62,67)(H,69,70)/t34-,35-,43-,44-,45-,47-,48-,49-/m0/s1	WTUKWAHKXMTYEJ-GEAHHQELSA-N	50032180	(S)-2-[(2S,3S)-2-((2S,3S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL216082	Endothelin-1 receptor			 580							ChEMBL	10.1021/jm00015a003	10.7270/Q2KD1WZQ	7636842			Cody, WL; He, JX; DePue, PL; Waite, LA; Leonard, DM; Sefler, AM; Kaltenbronn, JS; Haleen, SJ; Walker, DM; Flynn, MA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032180&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44328087	103940730		CHEMBL216082					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50046869	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl	InChI=1S/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)20-27-18/h3-5,7,21H,6,8H2,1-2H3	PHWXUGHIIBDVKD-UHFFFAOYSA-N	50058126	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide (Sitaxsentan)::2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-5-methyl-benzoic acid isopropyl ester::CHEMBL282724::Sitaxentan	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058126&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			216235	103954105		CHEMBL282724	DB06268	3950		ZINC01481831	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048444	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(=O)N2CCN(CC2)c2ccccc2)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)c1cccs1	InChI=1S/C45H53N9O11S/c1-25(2)19-30-40(60)47-31(20-26-24-46-29-12-7-6-11-28(26)29)41(61)49-33(22-37(56)57)43(63)48-32(21-36(55)54-16-14-53(15-17-54)27-9-4-3-5-10-27)42(62)50-34(23-38(58)59)44(64)52-39(45(65)51-30)35-13-8-18-66-35/h3-13,18,24-25,30-34,39,46H,14-17,19-23H2,1-2H3,(H,47,60)(H,48,63)(H,49,61)(H,50,62)(H,51,65)(H,52,64)(H,56,57)(H,58,59)/t30-,31+,32-,33+,34-,39+/m0/s1	HAHANBGRLRTDGL-HKJVWEGHSA-N	50454651	CHEMBL1205177::TAK-044	Endothelin-1 receptor			 0.240000							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454651&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			123883	225146291		CHEMBL1205177					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048464	CCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H37FN2O7S/c1-4-6-14-39(34,35)31(11-5-2)13-12-30-17-21(19-7-10-24-25(16-19)38-18-37-24)26(28(32)33)27(30)20-8-9-23(36-3)22(29)15-20/h7-10,15-16,21,26-27H,4-6,11-14,17-18H2,1-3H3,(H,32,33)/t21-,26-,27+/m1/s1	SISHUQWGICPIJE-ZFWHIUCFSA-N	50061096	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(butane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL323464	Endothelin-1 receptor			 0.380000							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061096&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10187997	103956683		CHEMBL323464				ZINC26954881	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048472	CCCN(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1)S(=O)(=O)CCCC(F)(F)F	InChI=1S/C28H34F4N2O7S/c1-3-10-34(42(37,38)13-4-9-28(30,31)32)12-11-33-16-20(18-5-8-23-24(15-18)41-17-40-23)25(27(35)36)26(33)19-6-7-22(39-2)21(29)14-19/h5-8,14-15,20,25-26H,3-4,9-13,16-17H2,1-2H3,(H,35,36)/t20-,25-,26+/m1/s1	BMNFTWGABWKVKN-VANUSSGQSA-N	50061078	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[propyl-(4,4,4-trifluoro-butane-1-sulfonyl)-amino]-ethyl}-pyrrolidine-3-carboxylic acid::CHEMBL419367	Endothelin-1 receptor			 0.055000							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061078&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10651488	103956665		CHEMBL419367				ZINC26952128	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048476	CCCCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H41FN2O7S/c1-4-6-7-8-16-41(36,37)33(13-5-2)15-14-32-19-23(21-9-12-26-27(18-21)40-20-39-26)28(30(34)35)29(32)22-10-11-25(38-3)24(31)17-22/h9-12,17-18,23,28-29H,4-8,13-16,19-20H2,1-3H3,(H,34,35)/t23-,28-,29+/m1/s1	WELUHUKTVXHVBY-ZPJFYFFZSA-N	50061085	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(hexane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid::CHEMBL109644	Endothelin-1 receptor			 0.140000							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061085&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10210629	103956672		CHEMBL109644				ZINC26973882	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048478	CCCN(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1)S(=O)(=O)CCCCl	InChI=1S/C27H34ClFN2O7S/c1-3-10-31(39(34,35)13-4-9-28)12-11-30-16-20(18-5-8-23-24(15-18)38-17-37-23)25(27(32)33)26(30)19-6-7-22(36-2)21(29)14-19/h5-8,14-15,20,25-26H,3-4,9-13,16-17H2,1-2H3,(H,32,33)/t20-,25-,26+/m1/s1	IPZKGERDMRMXJO-VANUSSGQSA-N	50061086	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(3-chloro-propane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL325581	Endothelin-1 receptor			 0.550000							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061086&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10603409	103956673		CHEMBL325581				ZINC26947207	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50048485	CCCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H39FN2O7S/c1-4-6-7-15-40(35,36)32(12-5-2)14-13-31-18-22(20-8-11-25-26(17-20)39-19-38-25)27(29(33)34)28(31)21-9-10-24(37-3)23(30)16-21/h8-11,16-17,22,27-28H,4-7,12-15,18-19H2,1-3H3,(H,33,34)/t22-,27-,28+/m1/s1	JVWVTPZZEHLARL-OFEZKSIWSA-N	50061074	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(pentane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid::A-182086::CHEMBL111277	Endothelin-1 receptor			 0.078000							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061074&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9916235	103956661		CHEMBL111277				ZINC03936863	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50051087	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor			 0.300000							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50051090	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)cc1	InChI=1S/C24H17ClO5/c25-18-9-7-17(8-10-18)24(27)19(12-15-4-2-1-3-5-15)22(23(26)30-24)16-6-11-20-21(13-16)29-14-28-20/h1-11,13,27H,12,14H2	HIOIBSDPMJWBMG-UHFFFAOYSA-N	50034257	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-chloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL267094	Endothelin-1 receptor			 430							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070783	103942458		CHEMBL267094				ZINC13740947	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052310	Cc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O5/c1-16-7-10-19(11-8-16)25(27)20(13-17-5-3-2-4-6-17)23(24(26)30-25)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,27H,13,15H2,1H3	HUUWRVJBRKRKHX-UHFFFAOYSA-N	50034258	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tolyl-5H-furan-2-one::CHEMBL273613	Endothelin-1 receptor			 4900							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9865706	103942459		CHEMBL273613				ZINC13740951	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052316	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(C)cc2)cc1	InChI=1S/C26H24O5/c1-17-4-8-19(9-5-17)24-23(16-18-6-12-21(29-2)13-7-18)26(28,31-25(24)27)20-10-14-22(30-3)15-11-20/h4-15,28H,16H2,1-3H3	OKZRQVZTVLKRLK-UHFFFAOYSA-N	50034262	5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-p-tolyl-5H-furan-2-one::CHEMBL10951	Endothelin-1 receptor			 570							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10047521	103942463		CHEMBL10951				ZINC13740971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052322	COc1ccc(cc1)C(=O)C(\Cc1cc(OC)c(OC)c(OC)c1)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-32-19-8-5-17(6-9-19)26(29)20(11-16-12-23(33-2)27(35-4)24(13-16)34-3)25(28(30)31)18-7-10-21-22(14-18)37-15-36-21/h5-10,12-14H,11,15H2,1-4H3,(H,30,31)/p-1/b25-20-	OFCTYBMKKTVKCR-QQTULTPQSA-M	50034263	CHEMBL25438::PD-156707::Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate	Endothelin-1 receptor			 0.31							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91929183	103942464		CHEMBL25438				ZINC03945732	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052328	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(OC)c(C)c1)c1ccc2OCOc2c1	InChI=1S/C27H24O7/c1-16-12-17(4-10-22(16)31-3)13-21-25(18-5-11-23-24(14-18)33-15-32-23)26(28)34-27(21,29)19-6-8-20(30-2)9-7-19/h4-12,14,29H,13,15H2,1-3H3	LCTRHYXOTRTJQR-UHFFFAOYSA-N	50034269	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-3-methyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10924	Endothelin-1 receptor			 6							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034269&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9890440	103942470		CHEMBL10924				ZINC13740963	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052329	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc1	InChI=1S/C26H22O7/c1-29-19-8-3-16(4-9-19)13-21-24(17-5-12-22-23(14-17)32-15-31-22)25(27)33-26(21,28)18-6-10-20(30-2)11-7-18/h3-12,14,28H,13,15H2,1-2H3	SUKHVLAHDGZTPC-UHFFFAOYSA-N	50034259	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11115	Endothelin-1 receptor			 1.8							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034259&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9955200	103942460		CHEMBL11115				ZINC13740959	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052330	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor			 0.3							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052336	COc1ccc(cc1C)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-16-12-19(9-11-21(16)29-2)26(28)20(13-17-6-4-3-5-7-17)24(25(27)32-26)18-8-10-22-23(14-18)31-15-30-22/h3-12,14,28H,13,15H2,1-2H3	WWMOPKHFPOIUHU-UHFFFAOYSA-N	50034270	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-3-methyl-phenyl)-5H-furan-2-one::CHEMBL10588	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034270&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10342643	103942471		CHEMBL10588				ZINC13740955	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052337	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)cc1	InChI=1S/C24H17ClO5/c25-18-9-7-17(8-10-18)24(27)19(12-15-4-2-1-3-5-15)22(23(26)30-24)16-6-11-20-21(13-16)29-14-28-20/h1-11,13,27H,12,14H2	HIOIBSDPMJWBMG-UHFFFAOYSA-N	50034257	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-chloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL267094	Endothelin-1 receptor			 430							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070783	103942458		CHEMBL267094				ZINC13740947	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052339	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C24H18O5/c25-23-22(17-11-12-20-21(14-17)28-15-27-20)19(13-16-7-3-1-4-8-16)24(26,29-23)18-9-5-2-6-10-18/h1-12,14,26H,13,15H2	SDCJODJPKKXXTB-UHFFFAOYSA-N	50034255	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-phenyl-5H-furan-2-one::CHEMBL11131	Endothelin-1 receptor			 600							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034255&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			345351	103942456		CHEMBL11131				ZINC06574969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052347	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)c(Cl)c1	InChI=1S/C24H16Cl2O5/c25-18-8-7-16(12-19(18)26)24(28)17(10-14-4-2-1-3-5-14)22(23(27)31-24)15-6-9-20-21(11-15)30-13-29-20/h1-9,11-12,28H,10,13H2	GTADCEYWHLRYOB-UHFFFAOYSA-N	50034260	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dichloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL275991	Endothelin-1 receptor			 560							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10027018	103942461		CHEMBL275991				ZINC13740953	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052349	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-28-19-10-8-18(9-11-19)25(27)20(13-16-5-3-2-4-6-16)23(24(26)31-25)17-7-12-21-22(14-17)30-15-29-21/h2-12,14,27H,13,15H2,1H3	JZHLIUOZBXWYGJ-UHFFFAOYSA-N	50034256	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL274383::PD-155080	Endothelin-1 receptor			 50							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034256&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11742628	103942457		CHEMBL274383				ZINC13740949	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052354	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(Cl)c(Cl)c2)cc1	InChI=1S/C25H20Cl2O5/c1-30-18-8-3-15(4-9-18)13-20-23(16-5-12-21(26)22(27)14-16)24(28)32-25(20,29)17-6-10-19(31-2)11-7-17/h3-12,14,29H,13H2,1-2H3	RYEVVTBWAHSOKY-UHFFFAOYSA-N	50034266	3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10996	Endothelin-1 receptor			 170							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10412464	103942467		CHEMBL10996				ZINC13740973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052356	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(Cl)cc2)cc1	InChI=1S/C25H21ClO5/c1-29-20-11-3-16(4-12-20)15-22-23(17-5-9-19(26)10-6-17)24(27)31-25(22,28)18-7-13-21(30-2)14-8-18/h3-14,28H,15H2,1-2H3	RQUIHRSTPLMWSU-UHFFFAOYSA-N	50034254	3-(4-Chloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10648	Endothelin-1 receptor			 700							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034254&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9980487	103942455		CHEMBL10648				ZINC13740967	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052357	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccccc2)cc1	InChI=1S/C25H22O5/c1-28-20-12-8-17(9-13-20)16-22-23(18-6-4-3-5-7-18)24(26)30-25(22,27)19-10-14-21(29-2)15-11-19/h3-15,27H,16H2,1-2H3	GCLJDQQEPIRTNF-UHFFFAOYSA-N	50034261	5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL10897	Endothelin-1 receptor			 2000							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034261&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10024044	103942462		CHEMBL10897				ZINC13740965	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052359	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(C)cc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-16-3-5-17(6-4-16)13-21-24(18-7-12-22-23(14-18)31-15-30-22)25(27)32-26(21,28)19-8-10-20(29-2)11-9-19/h3-12,14,28H,13,15H2,1-2H3	SGMHXYMWOLAIMX-UHFFFAOYSA-N	50034265	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-methyl-benzyl)-5H-furan-2-one::CHEMBL10374	Endothelin-1 receptor			 50							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9845562	103942466		CHEMBL10374				ZINC13740961	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052360	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(OC)cc2)cc1	InChI=1S/C26H24O6/c1-29-20-10-4-17(5-11-20)16-23-24(18-6-12-21(30-2)13-7-18)25(27)32-26(23,28)19-8-14-22(31-3)15-9-19/h4-15,28H,16H2,1-3H3	JCPFQTABMZGRMJ-UHFFFAOYSA-N	50034268	5-Hydroxy-4-(4-methoxy-benzyl)-3,5-bis-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11162	Endothelin-1 receptor			 310							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034268&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10410546	103942469		CHEMBL11162				ZINC13740969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50052362	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1ccc2OCOc2c1	InChI=1S/C25H19ClO6/c1-29-19-9-5-17(6-10-19)25(28)20(12-15-2-7-18(26)8-3-15)23(24(27)32-25)16-4-11-21-22(13-16)31-14-30-21/h2-11,13,28H,12,14H2,1H3	BIXNVCGHAZAOLY-UHFFFAOYSA-N	50034264	3-Benzo[1,3]dioxol-5-yl-4-(4-chloro-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10733	Endothelin-1 receptor			 140							ChEMBL	10.1021/jm00008a002	10.7270/Q2WH2P1B	7731010			Doherty, AM; Patt, WC; Edmunds, JJ; Berryman, KA; Reisdorph, BR; Plummer, MS; Shahripour, A; Lee, C; Cheng, XM; Walker, DM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11744509	103942465		CHEMBL10733				ZINC13740957	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50053676	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1cc2OCOc2c(OC)c1	InChI=1S/C30H48N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h15-16,22-23,27H,7-14,17-20H2,1-6H3,(H,34,35)/t22-,23+,27-/m1/s1	OAEWNSKRLBVVBV-QSEAXJEQSA-N	50066391	(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::CHEMBL111612	Endothelin-1 receptor		 0.460000								ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066391&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915028	103961033		CHEMBL111612				ZINC04394021	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50060337	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1	InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)	YOSHYTLCDANDAN-UHFFFAOYSA-N	50042235	2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::BMS 186295::CHEMBL1513::IRBESARTAN	Endothelin-1 receptor		>0.000100								ChEMBL	10.1021/jm020138n	10.7270/Q2Z60NDM	12190306			Murugesan, N; Tellew, JE; Gu, Z; Kunst, BL; Fadnis, L; Cornelius, LA; Baska, RA; Yang, Y; Beyer, SM; Monshizadegan, H; Dickinson, KE; Panchal, B; Valentine, MT; Chong, S; Morrison, RA; Carlson, KE; Powell, JR; Moreland, S; Barrish, JC; Kowala, MC; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3749	103973843		CHEMBL1513		589	C07469	ZINC13298436	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50060593	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30+,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-DZZYDSNESA-N	50000566	(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-((S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL289687	Endothelin-1 receptor			 8900							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000566&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284284	103915114		CHEMBL289687				ZINC95607973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50060594	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35+,36-,37-,38-,40-,41-/m0/s1	GNRBLKLDFZWDTC-ALDIRDDTSA-N	50045244	(S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-D-Phe-Asp-Ile-Ile-Trp::CHEMBL313984	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045244&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321226	103976335		CHEMBL313984					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066126	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H26O6/c1-3-12-31-19-9-10-20-21(14-19)24(16-4-7-18(30-2)8-5-16)26(27(28)29)25(20)17-6-11-22-23(13-17)33-15-32-22/h4-11,13-14,24-26H,3,12,15H2,1-2H3,(H,28,29)/t24-,25+,26+/m1/s1	MGSHGXWTVFBUSC-ZNZIZOMTSA-N	50041616	(1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid::CHEMBL39142	Endothelin-1 receptor		 11.3								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041616&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10321341	103973306		CHEMBL39142				ZINC13736725	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066128	COc1ccc(cc1)[C@@H]1[C@H]([C@@H](c2ccccc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C24H20O5/c1-27-16-9-6-14(7-10-16)21-17-4-2-3-5-18(17)22(23(21)24(25)26)15-8-11-19-20(12-15)29-13-28-19/h2-12,21-23H,13H2,1H3,(H,25,26)/t21-,22+,23+/m0/s1	QDRPQGXYQQITQV-YTFSRNRJSA-N	50041618	(1R,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-phenyl)-indan-2-carboxylic acid::CHEMBL38537	Endothelin-1 receptor		 43								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041618&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10045790	103973308		CHEMBL38537				ZINC13736722	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066129	COc1ccc(cc1)[C@@H]1[C@H]([C@@H](c2ccccc12)c1ccccc1)C(O)=O	InChI=1S/C23H20O3/c1-26-17-13-11-16(12-14-17)21-19-10-6-5-9-18(19)20(22(21)23(24)25)15-7-3-2-4-8-15/h2-14,20-22H,1H3,(H,24,25)/t20-,21+,22+/m1/s1	MGYLWKSNZPWGEK-FSSWDIPSSA-N	50041619	(1S,2S,3R)-1-(4-Methoxy-phenyl)-3-phenyl-indan-2-carboxylic acid::CHEMBL39057	Endothelin-1 receptor		 5666.0								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041619&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10088869	103973309		CHEMBL39057				ZINC13736718	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066130	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-3-10-35-18-6-7-19-21(12-18)27(20-8-5-17(34-2)13-23(20)36-14-25(30)31)28(29(32)33)26(19)16-4-9-22-24(11-16)38-15-37-22/h4-9,11-13,26-28H,3,10,14-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27+,28+/m0/s1	UUAVCCWBNUITBB-UPRLRBBYSA-N	50041617	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid::1-benzo[d][1,3]dioxol-5-ylmethyl-3-(2-carboxymethoxy-4-methoxyphenyl)-5-propoxy-(1R,3S)-2,3-dihydro-1H-2-indenecarboxylic acid::CHEMBL8823::SB 209670::SB-209670	Endothelin-1 receptor		 0.43								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			108002	103973307		CHEMBL8823		3528		ZINC01536124	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066134	OC(=O)[C@H]1[C@@H](c2ccccc2[C@@H]1c1ccccc1)c1ccccc1	InChI=1S/C22H18O2/c23-22(24)21-19(15-9-3-1-4-10-15)17-13-7-8-14-18(17)20(21)16-11-5-2-6-12-16/h1-14,19-21H,(H,23,24)/t19-,20+,21+	XEURUJDIFBUEKG-AERCQKQUSA-N	50041620	(1R,2R,3S)-1,3-Diphenyl-indan-2-carboxylic acid::CHEMBL39171	Endothelin-1 receptor		 11222								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041620&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44286764	103973310		CHEMBL39171				ZINC13736716	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066136	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(O)cc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C24H20O6/c1-28-16-6-2-13(3-7-16)21-18-11-15(25)5-8-17(18)22(23(21)24(26)27)14-4-9-19-20(10-14)30-12-29-19/h2-11,21-23,25H,12H2,1H3,(H,26,27)/t21-,22+,23+/m1/s1	BJSXTKDRYZUWEL-VJBWXMMDSA-N	50041622	(1S,2S,3R)-1-Benzo[1,3]dioxol-5-yl-5-hydroxy-3-(4-methoxy-phenyl)-indan-2-carboxylic acid::CHEMBL41087	Endothelin-1 receptor		 15								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041622&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10453858	103973312		CHEMBL41087				ZINC13736724	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50066137	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccccc12)c1ccc(OC)cc1)C(O)=O	InChI=1S/C24H22O4/c1-27-17-11-7-15(8-12-17)21-19-5-3-4-6-20(19)22(23(21)24(25)26)16-9-13-18(28-2)14-10-16/h3-14,21-23H,1-2H3,(H,25,26)/t21-,22+,23+	FZNLSLGOBKSDLA-JKHIJQBDSA-N	50041621	(1R,2R,3S)-1,3-Bis-(4-methoxy-phenyl)-indan-2-carboxylic acid::CHEMBL290026	Endothelin-1 receptor		 422.0								ChEMBL	10.1021/jm00037a003	10.7270/Q2154G2V	8201588			Elliott, JD; Lago, MA; Cousins, RD; Gao, A; Leber, JD; Erhard, KF; Nambi, P; Elshourbagy, NA; Kumar, C; Lee, JA	SmithKline Beecham Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041621&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10407051	103973311		CHEMBL290026				ZINC13736720	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070886	CN(C)c1ccc(cc1)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C13H17N3O3S/c1-9-10(2)14-19-13(9)15-20(17,18)12-7-5-11(6-8-12)16(3)4/h5-8,15H,1-4H3	WCXNJFBONDLQBP-UHFFFAOYSA-N	50036288	4-Dimethylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL332471	Endothelin-1 receptor			 84000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036288&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14973488	103944106		CHEMBL332471				ZINC13602363	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070887	CC(=C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C18H18N2O3S/c1-11(2)14-7-5-9-16-15(14)8-6-10-17(16)24(21,22)20-18-12(3)13(4)19-23-18/h5-10,20H,1H2,2-4H3	ZRRPWYSCRYJBJK-UHFFFAOYSA-N	50034410	5-Isopropenyl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL281942	Endothelin-1 receptor			 5700							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034410&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10043017	103942611		CHEMBL281942				ZINC13734249	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070888	COc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C16H16N2O4S/c1-10-11(2)17-22-16(10)18-23(19,20)15-9-5-6-12-13(15)7-4-8-14(12)21-3/h4-9,18H,1-3H3	WNTHOLVCVUVGCW-UHFFFAOYSA-N	50034462	5-Methoxy-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL28692	Endothelin-1 receptor			 6500							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034462&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10449431	103942663		CHEMBL28692				ZINC13734251	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070889	Cc1noc(NS(=O)(=O)c2cccc3ccccc23)c1C	InChI=1S/C15H14N2O3S/c1-10-11(2)16-20-15(10)17-21(18,19)14-9-5-7-12-6-3-4-8-13(12)14/h3-9,17H,1-2H3	ZEOXLCVRBAOHIV-UHFFFAOYSA-N	50034446	CHEMBL27065::Naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide	Endothelin-1 receptor			 20000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034446&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10357554	103942647		CHEMBL27065				ZINC13602327	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070872	Cc1noc(NS(=O)(=O)c2cccc3c(N)cccc23)c1C	InChI=1S/C15H15N3O3S/c1-9-10(2)17-21-15(9)18-22(19,20)14-8-4-5-11-12(14)6-3-7-13(11)16/h3-8,18H,16H2,1-2H3	ZROYYHDKAAJDKF-UHFFFAOYSA-N	50034450	5-Amino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL30039	Endothelin-1 receptor			 4000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034450&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10087191	103942651		CHEMBL30039				ZINC00016702	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070873	Cc1noc(NS(=O)(=O)c2cccc3c(O)cccc23)c1C	InChI=1S/C15H14N2O4S/c1-9-10(2)16-21-15(9)17-22(19,20)14-8-4-5-11-12(14)6-3-7-13(11)18/h3-8,17-18H,1-2H3	YOPBFWQDJCIHDV-UHFFFAOYSA-N	50034418	5-Hydroxy-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL30228	Endothelin-1 receptor			 7800							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034418&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10336018	103942619		CHEMBL30228				ZINC13602335	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070874	CC(=O)Nc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H17N3O4S/c1-10-11(2)19-24-17(10)20-25(22,23)16-9-5-6-13-14(16)7-4-8-15(13)18-12(3)21/h4-9,20H,1-3H3,(H,18,21)	RUCGYYIEJGBLLO-UHFFFAOYSA-N	50034465	CHEMBL30199::N-[5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalen-1-yl]-acetamide	Endothelin-1 receptor			 880.0							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034465&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10338501	103942666		CHEMBL30199				ZINC13602332	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070876	Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C	InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3	NHUHCSRWZMLRLA-UHFFFAOYSA-N	50034452	4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL453::Eryzole::Gantrisin::Pediazole::SULFISOXAZOLE::Sosol::Soxazole::Sulfafurazole::Sulfalar::Sulfisoxazol::Sulphafurazole::Sulsoxin	Endothelin-1 receptor			 780.0							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034452&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5344	103942653	102484	CHEMBL453	DB00263		C07318	ZINC96006009	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070877	Cc1noc(NS(=O)(=O)c2ccc(NCc3ccccc3)cc2)c1C	InChI=1S/C18H19N3O3S/c1-13-14(2)20-24-18(13)21-25(22,23)17-10-8-16(9-11-17)19-12-15-6-4-3-5-7-15/h3-11,19,21H,12H2,1-2H3	HADQVLLXWGMTEP-UHFFFAOYSA-N	50034468	4-Benzylamino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL25730	Endothelin-1 receptor			 9800.0							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034468&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10021240	103942669		CHEMBL25730				ZINC13734240	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070878	Cc1noc(NS(=O)(=O)c2ccc(cc2)C#N)c1C	InChI=1S/C12H11N3O3S/c1-8-9(2)14-18-12(8)15-19(16,17)11-5-3-10(7-13)4-6-11/h3-6,15H,1-2H3	ZOZSDSQUJKFDJF-UHFFFAOYSA-N	50044084	4-Cyano-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL325690	Endothelin-1 receptor			>32000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044084	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044084&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14973489	103975454		CHEMBL325690				ZINC13734243	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070879	Cc1cc(NS(=O)(=O)c2ccc(N)cc2)on1	InChI=1S/C10H11N3O3S/c1-7-6-10(16-12-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6,13H,11H2,1H3	KBLGZYOVYFTAOB-UHFFFAOYSA-N	50034474	4-Amino-N-(3-methyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL283941	Endothelin-1 receptor			 28000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034474&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10444974	103942675		CHEMBL283941				ZINC13734228	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070880	CCCNc1ccc(cc1)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C14H19N3O3S/c1-4-9-15-12-5-7-13(8-6-12)21(18,19)17-14-10(2)11(3)16-20-14/h5-8,15,17H,4,9H2,1-3H3	ARYCFFYGDKYENL-UHFFFAOYSA-N	50034440	CHEMBL286682::N-(3,4-Dimethyl-isoxazol-5-yl)-4-propylamino-benzenesulfonamide	Endothelin-1 receptor			 27000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034440&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10470588	103942641		CHEMBL286682				ZINC13734237	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070881	Cc1noc(NS(=O)(=O)c2ccc(O)cc2)c1C	InChI=1S/C11H12N2O4S/c1-7-8(2)12-17-11(7)13-18(15,16)10-5-3-9(14)4-6-10/h3-6,13-14H,1-2H3	WXHUJRKRFANUNH-UHFFFAOYSA-N	50034461	CHEMBL282961::N-(3,4-Dimethyl-isoxazol-5-yl)-4-hydroxy-benzenesulfonamide	Endothelin-1 receptor			 9200.0							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034461&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10015852	103942662		CHEMBL282961				ZINC13602366	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070882	CN(C)Cc1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C18H21N3O3S/c1-12-13(2)19-24-18(12)20-25(22,23)17-10-6-8-15-14(11-21(3)4)7-5-9-16(15)17/h5-10,20H,11H2,1-4H3	LDGOBRDRWRXUKR-UHFFFAOYSA-N	50034437	5-Dimethylaminomethyl-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL27525	Endothelin-1 receptor			 2800							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034437&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10247887	103942638		CHEMBL27525				ZINC13734246	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070883	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor			 150							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50070884	Cc1noc(NS(=O)(=O)c2cccc3c(cccc23)C(O)=O)c1C	InChI=1S/C16H14N2O5S/c1-9-10(2)17-23-15(9)18-24(21,22)14-8-4-5-11-12(14)6-3-7-13(11)16(19)20/h3-8,18H,1-2H3,(H,19,20)	XZVLKLYTZGMQQJ-UHFFFAOYSA-N	50034441	5-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-naphthalene-1-carboxylic acid::CHEMBL30246	Endothelin-1 receptor			 13000							ChEMBL	10.1021/jm00029a001	10.7270/Q24M93KB	8308857			Stein, PD; Hunt, JT; Floyd, DM; Moreland, S; Dickinson, KE; Mitchell, C; Liu, EC; Webb, ML; Murugesan, N; Dickey, J	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034441&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10337668	103942642		CHEMBL30246				ZINC13734254	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083334	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-3-10-35-18-6-7-19-21(12-18)27(20-8-5-17(34-2)13-23(20)36-14-25(30)31)28(29(32)33)26(19)16-4-9-22-24(11-16)38-15-37-22/h4-9,11-13,26-28H,3,10,14-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27+,28+/m0/s1	UUAVCCWBNUITBB-UPRLRBBYSA-N	50041617	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid::1-benzo[d][1,3]dioxol-5-ylmethyl-3-(2-carboxymethoxy-4-methoxyphenyl)-5-propoxy-(1R,3S)-2,3-dihydro-1H-2-indenecarboxylic acid::CHEMBL8823::SB 209670::SB-209670	Endothelin-1 receptor		 0.43								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			108002	103973307		CHEMBL8823		3528		ZINC01536124	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083336	CCCc1cc(ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C28H29NO8S/c1-4-5-19-14-21(28(31)32)9-12-23(19)37-26(20-8-13-24-25(15-20)36-16-35-24)27(30)29-38(33,34)22-10-6-18(7-11-22)17(2)3/h6-15,17,26H,4-5,16H2,1-3H3,(H,29,30)(H,31,32)	JPPYWKVKLSBQJM-UHFFFAOYSA-N	50050964	4-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethoxy]-3-propyl-benzoic acid::CHEMBL8978::L-754142	Endothelin-1 receptor		 0.13								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050964&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9894460	103948055		CHEMBL8978				ZINC25993182	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083342	CCCCN(CCCC)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m0/s1	MOTJMGVDPWRKOC-MXSCXNJPSA-N	50050970	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL428504	Endothelin-1 receptor		 63								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050970&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5310990	103948061		CHEMBL428504		3487		ZINC03812143	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083344	CCCCN(CCC)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H36N2O6/c1-4-6-14-29(13-5-2)25(31)17-30-16-22(20-9-12-23-24(15-20)36-18-35-23)26(28(32)33)27(30)19-7-10-21(34-3)11-8-19/h7-12,15,22,26-27H,4-6,13-14,16-18H2,1-3H3,(H,32,33)/t22-,26-,27+/m0/s1	BSMQWDCPKODFQI-WDDWZANVSA-N	50050975	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(butyl-propyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL9334	Endothelin-1 receptor			 0.81							ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050975&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10648937	103948066		CHEMBL9334				ZINC13746940	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083345	CCCCN(CCCC)C(=O)CN1CC(C(C1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)	MOTJMGVDPWRKOC-UHFFFAOYSA-N	50050976	4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL8923	Endothelin-1 receptor			 0.11							ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050976&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9914310	103948067		CHEMBL8923				ZINC34026477	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083354	CCCCN(C)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H32N2O6/c1-4-5-12-27(2)23(29)15-28-14-20(18-8-11-21-22(13-18)34-16-33-21)24(26(30)31)25(28)17-6-9-19(32-3)10-7-17/h6-11,13,20,24-25H,4-5,12,14-16H2,1-3H3,(H,30,31)/t20-,24-,25+/m0/s1	MMOXDQVSZSVDLF-KSNOWIBYSA-N	50050987	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-[(butyl-methyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL267695	Endothelin-1 receptor			 4.88							ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050987&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11798504	103948078		CHEMBL267695				ZINC13746918	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083361	CCCN(C)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C25H30N2O6/c1-4-11-26(2)22(28)14-27-13-19(17-7-10-20-21(12-17)33-15-32-20)23(25(29)30)24(27)16-5-8-18(31-3)9-6-16/h5-10,12,19,23-24H,4,11,13-15H2,1-3H3,(H,29,30)/t19-,23-,24+/m0/s1	NDHGXDPUEOMCNE-WDJPJFJCSA-N	50050984	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid::CHEMBL266594	Endothelin-1 receptor			 21.3							ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050984&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10527706	103948075		CHEMBL266594				ZINC13746916	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083385	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor		 0.17								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083400	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m1/s1	MOTJMGVDPWRKOC-QPVYNBJUSA-N	50051007	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::A-127722::CHEMBL9194	Endothelin-1 receptor		 0.034								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			159594	103948098		CHEMBL9194				ZINC03812144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083407	COc1ccccc1Cc1c(CCCO)nc(nc1NS(=O)(=O)c1ccc(cc1)C(C)(C)C)-c1ncccn1	InChI=1S/C29H33N5O4S/c1-29(2,3)21-12-14-22(15-13-21)39(36,37)34-26-23(19-20-9-5-6-11-25(20)38-4)24(10-7-18-35)32-28(33-26)27-30-16-8-17-31-27/h5-6,8-9,11-17,35H,7,10,18-19H2,1-4H3,(H,32,33,34)	NEOVBIIJKPUROI-UHFFFAOYSA-N	50051012	4-tert-Butyl-N-[6-(3-hydroxy-propyl)-5-(2-methoxy-benzyl)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL428661	Endothelin-1 receptor		 6.5								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051012&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44265871	103948103		CHEMBL428661				ZINC25994684	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083417	CCCNC(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C24H28N2O6/c1-3-10-25-21(27)13-26-12-18(16-6-9-19-20(11-16)32-14-31-19)22(24(28)29)23(26)15-4-7-17(30-2)8-5-15/h4-9,11,18,22-23H,3,10,12-14H2,1-2H3,(H,25,27)(H,28,29)/t18-,22-,23+/m0/s1	AIVZWVQMNJFOIL-OFAXGOBFSA-N	50050979	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-propylcarbamoylmethyl-pyrrolidine-3-carboxylic acid::CHEMBL9141	Endothelin-1 receptor			 45.3							ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050979&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10599230	103948070		CHEMBL9141				ZINC13746904	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081364	CC(C)C[C@H](NC(=O)N(C)C1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C30H42N6O4/c1-18(2)15-24(33-30(40)36(5)21-11-7-6-8-12-21)28(37)32-23(27-31-19(3)26(34-27)29(38)39)16-20-17-35(4)25-14-10-9-13-22(20)25/h9-10,13-14,17-18,21,23-24H,6-8,11-12,15-16H2,1-5H3,(H,31,34)(H,32,37)(H,33,40)(H,38,39)/t23-,24+/m1/s1	JUYJVWUMDGZHSF-RPWUZVMVSA-N	50050056	2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL414605	Endothelin-1 receptor			 1.8							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050056&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11800804	103947261		CHEMBL414605				ZINC28102179	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081366	CC(C)C[C@H](CC(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C30H40N4O5/c1-18(2)14-20(16-26(35)31-22-10-6-5-7-11-22)28(36)32-24(29-33-27(30(37)38)19(3)39-29)15-21-17-34(4)25-13-9-8-12-23(21)25/h8-9,12-13,17-18,20,22,24H,5-7,10-11,14-16H2,1-4H3,(H,31,35)(H,32,36)(H,37,38)/t20-,24-/m1/s1	PNMVPOFSIZYXEJ-HYBUGGRVSA-N	50050054	2-[(R)-1-((R)-2-Cyclohexylcarbamoylmethyl-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL177839	Endothelin-1 receptor			 310							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050054&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11800505	103947259		CHEMBL177839				ZINC28107402	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081368	CC(C)C[C@H](N(C)C(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C30H41N5O5/c1-18(2)15-25(35(5)30(39)31-21-11-7-6-8-12-21)27(36)32-23(28-33-26(29(37)38)19(3)40-28)16-20-17-34(4)24-14-10-9-13-22(20)24/h9-10,13-14,17-18,21,23,25H,6-8,11-12,15-16H2,1-5H3,(H,31,39)(H,32,36)(H,37,38)/t23-,25+/m1/s1	VKVUQJMVRPZBIO-NOZRDPDXSA-N	50050052	2-[(R)-1-[(S)-2-(3-Cyclohexyl-1-methyl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL369821	Endothelin-1 receptor			 450							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050052&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10650331	103947257		CHEMBL369821				ZINC28110236	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081369	CC(C)C[C@H](NC(=O)N(C)C1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C30H41N5O5/c1-18(2)15-23(32-30(39)35(5)21-11-7-6-8-12-21)27(36)31-24(28-33-26(29(37)38)19(3)40-28)16-20-17-34(4)25-14-10-9-13-22(20)25/h9-10,13-14,17-18,21,23-24H,6-8,11-12,15-16H2,1-5H3,(H,31,36)(H,32,39)(H,37,38)/t23-,24+/m0/s1	CYNRTRAOTKDFNE-BJKOFHAPSA-N	50050059	2-[(R)-1-[(S)-2-(3-Cyclohexyl-3-methyl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL174699	Endothelin-1 receptor			 25							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050059&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10792783	103947264		CHEMBL174699				ZINC28100465	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081370	CC(C)C[C@H](NC(=O)OC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C29H38N4O6/c1-17(2)14-22(31-29(37)39-20-10-6-5-7-11-20)26(34)30-23(27-32-25(28(35)36)18(3)38-27)15-19-16-33(4)24-13-9-8-12-21(19)24/h8-9,12-13,16-17,20,22-23H,5-7,10-11,14-15H2,1-4H3,(H,30,34)(H,31,37)(H,35,36)/t22-,23+/m0/s1	NVCMJDTXNXADGH-XZOQPEGZSA-N	50050060	2-[(R)-1-((S)-2-Cyclohexyloxycarbonylamino-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL353320	Endothelin-1 receptor			 41							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050060&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10554410	103947265		CHEMBL353320				ZINC03935660	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081371	CC(C)C[C@H](NC(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C29H39N5O5/c1-17(2)14-22(32-29(38)30-20-10-6-5-7-11-20)26(35)31-23(27-33-25(28(36)37)18(3)39-27)15-19-16-34(4)24-13-9-8-12-21(19)24/h8-9,12-13,16-17,20,22-23H,5-7,10-11,14-15H2,1-4H3,(H,31,35)(H,36,37)(H2,30,32,38)/t22-,23+/m0/s1	MAKSAWWTYOIXFZ-XZOQPEGZSA-N	50050042	2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL441112	Endothelin-1 receptor			 220							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050042&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10554384	103947247		CHEMBL441112				ZINC03935661	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081372	CC(C)C[C@H](CC(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C30H41N5O4/c1-18(2)14-20(16-26(36)32-22-10-6-5-7-11-22)29(37)33-24(28-31-19(3)27(34-28)30(38)39)15-21-17-35(4)25-13-9-8-12-23(21)25/h8-9,12-13,17-18,20,22,24H,5-7,10-11,14-16H2,1-4H3,(H,31,34)(H,32,36)(H,33,37)(H,38,39)/t20-,24-/m1/s1	VWBNQTBYAHOFDQ-HYBUGGRVSA-N	50050061	2-[(R)-1-((R)-2-Cyclohexylcarbamoylmethyl-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL366805	Endothelin-1 receptor			 29							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050061&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10506505	103947266		CHEMBL366805				ZINC28100469	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081373	CC(C)C[C@H](NC(=O)CC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C30H40N4O5/c1-18(2)14-23(31-26(35)15-20-10-6-5-7-11-20)28(36)32-24(29-33-27(30(37)38)19(3)39-29)16-21-17-34(4)25-13-9-8-12-22(21)25/h8-9,12-13,17-18,20,23-24H,5-7,10-11,14-16H2,1-4H3,(H,31,35)(H,32,36)(H,37,38)/t23-,24+/m0/s1	UAYDAFZHDUZNPZ-BJKOFHAPSA-N	50050053	2-[(R)-1-[(S)-2-(2-Cyclohexyl-acetylamino)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL177179	Endothelin-1 receptor			 680.0							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050053&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10602451	103947258		CHEMBL177179				ZINC28113272	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081374	CC(C)C[C@H](OC(=O)N(C)C1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C30H40N4O6/c1-18(2)15-25(40-30(38)34(5)21-11-7-6-8-12-21)27(35)31-23(28-32-26(29(36)37)19(3)39-28)16-20-17-33(4)24-14-10-9-13-22(20)24/h9-10,13-14,17-18,21,23,25H,6-8,11-12,15-16H2,1-5H3,(H,31,35)(H,36,37)/t23-,25+/m1/s1	VFJNRIMZXJQZIA-NOZRDPDXSA-N	50050063	2-[(R)-1-[(S)-2-(Cyclohexyl-methyl-carbamoyloxy)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL175698	Endothelin-1 receptor			 4.6							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050063	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050063&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9959298	103947268		CHEMBL175698				ZINC03936477	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081375	CC(C)C[C@H](NC(=O)OC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C29H39N5O5/c1-17(2)14-23(32-29(38)39-20-10-6-5-7-11-20)27(35)31-22(26-30-18(3)25(33-26)28(36)37)15-19-16-34(4)24-13-9-8-12-21(19)24/h8-9,12-13,16-17,20,22-23H,5-7,10-11,14-15H2,1-4H3,(H,30,33)(H,31,35)(H,32,38)(H,36,37)/t22-,23+/m1/s1	QUJDRPRAFGCPRB-PKTZIBPZSA-N	50050062	2-[(R)-1-((S)-2-Cyclohexyloxycarbonylamino-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL367645	Endothelin-1 receptor			 76							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050062&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10578300	103947267		CHEMBL367645				ZINC28096218	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081377	CC(C)C[C@H](OC(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C29H38N4O6/c1-17(2)14-24(39-29(37)30-20-10-6-5-7-11-20)26(34)31-22(27-32-25(28(35)36)18(3)38-27)15-19-16-33(4)23-13-9-8-12-21(19)23/h8-9,12-13,16-17,20,22,24H,5-7,10-11,14-15H2,1-4H3,(H,30,37)(H,31,34)(H,35,36)/t22-,24+/m1/s1	JBRMRKFUAREDQM-VWNXMTODSA-N	50050051	2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL177546	Endothelin-1 receptor			 21							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050051&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10673969	103947256		CHEMBL177546				ZINC28106026	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081383	CC(C)C[C@H](N(C)C(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C30H42N6O4/c1-18(2)15-25(36(5)30(40)32-21-11-7-6-8-12-21)28(37)33-23(27-31-19(3)26(34-27)29(38)39)16-20-17-35(4)24-14-10-9-13-22(20)24/h9-10,13-14,17-18,21,23,25H,6-8,11-12,15-16H2,1-5H3,(H,31,34)(H,32,40)(H,33,37)(H,38,39)/t23-,25+/m1/s1	GGGSQHCWNBTLSJ-NOZRDPDXSA-N	50050055	2-[(R)-1-[(S)-2-(3-Cyclohexyl-1-methyl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL367033	Endothelin-1 receptor			 22							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050055&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10578601	103947260		CHEMBL367033				ZINC03935655	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081384	CC(C)C[C@H](NC(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C29H40N6O4/c1-17(2)14-23(33-29(39)31-20-10-6-5-7-11-20)27(36)32-22(26-30-18(3)25(34-26)28(37)38)15-19-16-35(4)24-13-9-8-12-21(19)24/h8-9,12-13,16-17,20,22-23H,5-7,10-11,14-15H2,1-4H3,(H,30,34)(H,32,36)(H,37,38)(H2,31,33,39)/t22-,23+/m1/s1	QGQSORGTKDCUOS-PKTZIBPZSA-N	50050047	2-[(R)-1-[(S)-2-(3-Cyclohexyl-ureido)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL174448	Endothelin-1 receptor			 11							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050047&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10697633	103947252		CHEMBL174448				ZINC03935652	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081385	CC(C)C[C@H](OC(=O)OC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)o1	InChI=1S/C29H37N3O7/c1-17(2)14-24(39-29(36)38-20-10-6-5-7-11-20)26(33)30-22(27-31-25(28(34)35)18(3)37-27)15-19-16-32(4)23-13-9-8-12-21(19)23/h8-9,12-13,16-17,20,22,24H,5-7,10-11,14-15H2,1-4H3,(H,30,33)(H,34,35)/t22-,24+/m1/s1	PYCASCCEVIFVMW-VWNXMTODSA-N	50050064	2-[(R)-1-((S)-2-Cyclohexyloxycarbonyloxy-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-oxazole-4-carboxylic acid::CHEMBL368629	Endothelin-1 receptor			 17							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050064	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050064&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10626245	103947269		CHEMBL368629				ZINC28087373	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081386	CC(C)C[C@H](OC(=O)NC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C29H39N5O5/c1-17(2)14-24(39-29(38)31-20-10-6-5-7-11-20)27(35)32-22(26-30-18(3)25(33-26)28(36)37)15-19-16-34(4)23-13-9-8-12-21(19)23/h8-9,12-13,16-17,20,22,24H,5-7,10-11,14-15H2,1-4H3,(H,30,33)(H,31,38)(H,32,35)(H,36,37)/t22-,24+/m1/s1	FSHZBEPAMREIHF-VWNXMTODSA-N	50050058	2-[(R)-1-((S)-2-Cyclohexylcarbamoyloxy-4-methyl-pentanoylamino)-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL175228	Endothelin-1 receptor			 9.3							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050058&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10650062	103947263		CHEMBL175228				ZINC28096147	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50081388	CC(C)C[C@H](NC(=O)CC1CCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1	InChI=1S/C30H41N5O4/c1-18(2)14-24(32-26(36)15-20-10-6-5-7-11-20)29(37)33-23(28-31-19(3)27(34-28)30(38)39)16-21-17-35(4)25-13-9-8-12-22(21)25/h8-9,12-13,17-18,20,23-24H,5-7,10-11,14-16H2,1-4H3,(H,31,34)(H,32,36)(H,33,37)(H,38,39)/t23-,24+/m1/s1	WDJALAMRYSCDQD-RPWUZVMVSA-N	50050057	2-[(R)-1-[(S)-2-(2-Cyclohexyl-acetylamino)-4-methyl-pentanoylamino]-2-(1-methyl-1H-indol-3-yl)-ethyl]-5-methyl-1H-imidazole-4-carboxylic acid::CHEMBL174871	Endothelin-1 receptor			 470							ChEMBL	10.1021/jm9505932	10.7270/Q2DB80WG	8632421			von Geldern, TW; Hoffman, DJ; Kester, JA; Nellans, HN; Dayton, BD; Calzadilla, SV; Marsh, KC; Hernandez, L; Chiou, W; Dixon, DB; Wu-Wong, JR; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050057	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050057&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10626177	103947262		CHEMBL174871				ZINC28096225	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083476	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor		 48								ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50083493	CCCN(CCC)C(=O)CN1C[C@H]([C@@H]([C@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H34N2O6/c1-4-12-28(13-5-2)24(30)16-29-15-21(19-8-11-22-23(14-19)35-17-34-22)25(27(31)32)26(29)18-6-9-20(33-3)10-7-18/h6-11,14,21,25-26H,4-5,12-13,15-17H2,1-3H3,(H,31,32)/t21-,25-,26+/m0/s1	AEDZVHIKLJEHDR-OUIFVKKZSA-N	50050980	(2S,3S,4R)-4-Benzo[1,3]dioxol-5-yl-1-dipropylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL9139	Endothelin-1 receptor			 0.55							ChEMBL	10.1021/jm9505369	10.7270/Q29G5KWT	8676339			Winn, M; von Geldern, TW; Opgenorth, TJ; Jae, HS; Tasker, AS; Boyd, SA; Kester, JA; Mantei, RA; Bal, R; Sorensen, BK; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Novosad, EI; Hernandez, L; Marsh, KC	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050980&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10719598	103948071		CHEMBL9139				ZINC13746948	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082599	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccc(C)cc2)c2ccc(C)cc2)n1	InChI=1S/C24H26N2O6/c1-15-6-10-17(11-7-15)24(31-5,18-12-8-16(2)9-13-18)21(22(27)28)32-23-25-19(29-3)14-20(26-23)30-4/h6-14,21H,1-5H3,(H,27,28)	WZQLNTRMQXKHIJ-UHFFFAOYSA-N	50050791	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-di-p-tolyl-propionic acid::CHEMBL303034	Endothelin-1 receptor		 200								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050791&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10599129	103947884		CHEMBL303034				ZINC13756032	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082600	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2cccc(F)c2)c2cccc(F)c2)n1	InChI=1S/C22H20F2N2O6/c1-29-17-12-18(30-2)26-21(25-17)32-19(20(27)28)22(31-3,13-6-4-8-15(23)10-13)14-7-5-9-16(24)11-14/h4-12,19H,1-3H3,(H,27,28)	WAZSLZZZKKHKKE-UHFFFAOYSA-N	50050790	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(3-fluoro-phenyl)-3-methoxy-propionic acid::CHEMBL67536	Endothelin-1 receptor		 11								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050790&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10742005	103947883		CHEMBL67536				ZINC13756036	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082604	CCCOC(C(Oc1nc(OC)cc(OC)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C24H26N2O6/c1-4-15-31-24(17-11-7-5-8-12-17,18-13-9-6-10-14-18)21(22(27)28)32-23-25-19(29-2)16-20(26-23)30-3/h5-14,16,21H,4,15H2,1-3H3,(H,27,28)	JRJABVRRPWBSPB-UHFFFAOYSA-N	50050795	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-diphenyl-3-propoxy-propionic acid::CHEMBL67084	Endothelin-1 receptor		 19								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050795&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11797288	103947888		CHEMBL67084				ZINC13756047	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082609	COC(=O)C(Oc1nc(OC)cc(OC)n1)C(C)(Oc1ccc(SC)cc1)c1ccccc1	InChI=1S/C24H26N2O6S/c1-24(16-9-7-6-8-10-16,32-17-11-13-18(33-5)14-12-17)21(22(27)30-4)31-23-25-19(28-2)15-20(26-23)29-3/h6-15,21H,1-5H3	RDRXGODJFLFYPJ-UHFFFAOYSA-N	50050798	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-methylsulfanyl-phenoxy)-3-phenyl-butyric acid methyl ester::CHEMBL67957	Endothelin-1 receptor		 160								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050798&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44307287	103947891		CHEMBL67957				ZINC26254181	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082611	COc1nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)nc2CCCc12	InChI=1S/C24H24N2O5/c1-29-21-18-14-9-15-19(18)25-23(26-21)31-20(22(27)28)24(30-2,16-10-5-3-6-11-16)17-12-7-4-8-13-17/h3-8,10-13,20H,9,14-15H2,1-2H3,(H,27,28)	HMBISNTYKZVPJD-UHFFFAOYSA-N	50050793	3-Methoxy-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL302564	Endothelin-1 receptor		 0.4								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050793	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050793&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10432263	103947886		CHEMBL302564				ZINC13756064	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082614	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C22H22N2O6/c1-27-17-14-18(28-2)24-21(23-17)30-19(20(25)26)22(29-3,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-14,19H,1-3H3,(H,25,26)	FEJVSJIALLTFRP-UHFFFAOYSA-N	50050794	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL25344	Endothelin-1 receptor		 6								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050794&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9953358	103947887		CHEMBL25344				ZINC13756022	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082618	COc1cc(OC)nc(OC(C(O)=O)C(O)(c2ccccc2)c2ccccc2)n1	InChI=1S/C21H20N2O6/c1-27-16-13-17(28-2)23-20(22-16)29-18(19(24)25)21(26,14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-13,18,26H,1-2H3,(H,24,25)	XTPVBLFDYBIPGU-UHFFFAOYSA-N	50050803	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-hydroxy-3,3-diphenyl-propionic acid::CHEMBL63648	Endothelin-1 receptor		 130								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050803&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10692125	103947896		CHEMBL63648				ZINC13756055	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082623	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2cccc(C)c2)c2cccc(C)c2)n1	InChI=1S/C24H26N2O6/c1-15-8-6-10-17(12-15)24(31-5,18-11-7-9-16(2)13-18)21(22(27)28)32-23-25-19(29-3)14-20(26-23)30-4/h6-14,21H,1-5H3,(H,27,28)	ZPGGGSYEPLVKGB-UHFFFAOYSA-N	50050805	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-di-m-tolyl-propionic acid::CHEMBL65833	Endothelin-1 receptor		 24								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050805&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10670662	103947898		CHEMBL65833				ZINC13756041	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082624	COC(C(Oc1nc(C)cc(C)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)	OUJTZYPIHDYQMC-UHFFFAOYSA-N	50050806	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL302753	Endothelin-1 receptor		 1								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050806&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			197712	103947899		CHEMBL302753				ZINC03644203	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082627	COc1cccc(c1)C(OC)(C(Oc1nc(OC)cc(OC)n1)C(O)=O)c1cccc(OC)c1	InChI=1S/C24H26N2O8/c1-29-17-10-6-8-15(12-17)24(33-5,16-9-7-11-18(13-16)30-2)21(22(27)28)34-23-25-19(31-3)14-20(26-23)32-4/h6-14,21H,1-5H3,(H,27,28)	NKUABLQDYCDPIT-UHFFFAOYSA-N	50050788	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-bis-(3-methoxy-phenyl)-propionic acid::CHEMBL303390	Endothelin-1 receptor		 22								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050788&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10719157	103947881		CHEMBL303390				ZINC13756038	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082628	COC(=O)C(Oc1nc(OC)cc(OC)n1)C(C)(Oc1ccc(cc1)C(C)C)c1ccccc1	InChI=1S/C26H30N2O6/c1-17(2)18-12-14-20(15-13-18)34-26(3,19-10-8-7-9-11-19)23(24(29)32-6)33-25-27-21(30-4)16-22(28-25)31-5/h7-17,23H,1-6H3	GJGNTDZVUULBFL-UHFFFAOYSA-N	50050809	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(4-isopropyl-phenoxy)-3-phenyl-butyric acid methyl ester::CHEMBL67325	Endothelin-1 receptor		 250								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050809&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44307412	103947902		CHEMBL67325				ZINC26258339	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082631	COc1cc(OC)nc(OC(C(O)=O)C(Oc2ccccc2)(c2ccccc2)c2ccccc2)n1	InChI=1S/C27H24N2O6/c1-32-22-18-23(33-2)29-26(28-22)34-24(25(30)31)27(19-12-6-3-7-13-19,20-14-8-4-9-15-20)35-21-16-10-5-11-17-21/h3-18,24H,1-2H3,(H,30,31)	FMKPVIZIITXJDD-UHFFFAOYSA-N	50050792	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-phenoxy-3,3-diphenyl-propionic acid::CHEMBL66402	Endothelin-1 receptor		 86								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050792	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050792&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814297	103947885		CHEMBL66402				ZINC13756049	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082615	CCOc1cc(OCC)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C24H26N2O6/c1-4-30-19-16-20(31-5-2)26-23(25-19)32-21(22(27)28)24(29-3,17-12-8-6-9-13-17)18-14-10-7-11-15-18/h6-16,21H,4-5H2,1-3H3,(H,27,28)	OBYHMQLIVICHBK-UHFFFAOYSA-N	50050801	2-(4,6-Diethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL66893	Endothelin-1 receptor		 174								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050801&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10836754	103947894		CHEMBL66893				ZINC13756058	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082616	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccc(F)cc2)c2ccc(F)cc2)n1	InChI=1S/C22H20F2N2O6/c1-29-17-12-18(30-2)26-21(25-17)32-19(20(27)28)22(31-3,13-4-8-15(23)9-5-13)14-6-10-16(24)11-7-14/h4-12,19H,1-3H3,(H,27,28)	FTHTWZGSLVJZJB-UHFFFAOYSA-N	50050797	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(4-fluoro-phenyl)-3-methoxy-propionic acid::CHEMBL304721	Endothelin-1 receptor		 33								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050797&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10671031	103947890		CHEMBL304721				ZINC13756024	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082617	CCOC(C(Oc1nc(OC)cc(OC)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C23H24N2O6/c1-4-30-23(16-11-7-5-8-12-16,17-13-9-6-10-14-17)20(21(26)27)31-22-24-18(28-2)15-19(25-22)29-3/h5-15,20H,4H2,1-3H3,(H,26,27)	TTZWTGSBTVOGHQ-UHFFFAOYSA-N	50050802	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid::CHEMBL304778	Endothelin-1 receptor		 7								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050802&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10693607	103947895		CHEMBL304778				ZINC13756045	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082632	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccccc2F)c2ccccc2F)n1	InChI=1S/C22H20F2N2O6/c1-29-17-12-18(30-2)26-21(25-17)32-19(20(27)28)22(31-3,13-8-4-6-10-15(13)23)14-9-5-7-11-16(14)24/h4-12,19H,1-3H3,(H,27,28)	GDDNQACXSFFUGL-UHFFFAOYSA-N	50050808	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3,3-bis-(2-fluoro-phenyl)-3-methoxy-propionic acid::CHEMBL303501	Endothelin-1 receptor		 150								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050808&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10837085	103947901		CHEMBL303501				ZINC13756044	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082633	COc1nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)nc2OCCc12	InChI=1S/C23H22N2O6/c1-28-19-17-13-14-30-20(17)25-22(24-19)31-18(21(26)27)23(29-2,15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,18H,13-14H2,1-2H3,(H,26,27)	OQVTWUJKWGKZHT-UHFFFAOYSA-N	50050800	3-Methoxy-2-(4-methoxy-5,6-dihydro-furo[2,3-d]pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL305980	Endothelin-1 receptor		 0.9								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050800&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9979632	103947893		CHEMBL305980				ZINC13756061	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082634	CCc1cc(CC)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C24H26N2O4/c1-4-19-16-20(5-2)26-23(25-19)30-21(22(27)28)24(29-3,17-12-8-6-9-13-17)18-14-10-7-11-15-18/h6-16,21H,4-5H2,1-3H3,(H,27,28)	GUTFIONSOPXFFD-UHFFFAOYSA-N	50050796	2-(4,6-Diethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL418326	Endothelin-1 receptor		 1								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050796&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10763862	103947889		CHEMBL418326				ZINC13756072	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082636	COc1cc(OC)nc(OC(C(O)=O)C(OCCC(C)(C)C)(c2ccccc2)c2ccccc2)n1	InChI=1S/C27H32N2O6/c1-26(2,3)16-17-34-27(19-12-8-6-9-13-19,20-14-10-7-11-15-20)23(24(30)31)35-25-28-21(32-4)18-22(29-25)33-5/h6-15,18,23H,16-17H2,1-5H3,(H,30,31)	PPUGAGCZTJDLOJ-UHFFFAOYSA-N	50050804	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-(3,3-dimethyl-butoxy)-3,3-diphenyl-propionic acid::CHEMBL304173	Endothelin-1 receptor		 340								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050804&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10743346	103947897		CHEMBL304173				ZINC13756051	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082637	COC(C(Oc1nccc(C)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C21H20N2O4/c1-15-13-14-22-20(23-15)27-18(19(24)25)21(26-2,16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-14,18H,1-2H3,(H,24,25)	AIHUUIAJRNWVGQ-UHFFFAOYSA-N	50050810	3-Methoxy-2-(4-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL306218	Endothelin-1 receptor		 19								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050810&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5122650	103947903		CHEMBL306218				ZINC09435021	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082640	CCc1cc(C)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C23H24N2O4/c1-4-19-15-16(2)24-22(25-19)29-20(21(26)27)23(28-3,17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-15,20H,4H2,1-3H3,(H,26,27)	KYDWTWOSIICWFQ-UHFFFAOYSA-N	50050789	2-(4-Ethyl-6-methyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL305270	Endothelin-1 receptor		 0.7								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050789&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10786696	103947882		CHEMBL305270				ZINC13756074	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082644	COc1cc(C)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C22H22N2O5/c1-15-14-18(27-2)24-21(23-15)29-19(20(25)26)22(28-3,16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-14,19H,1-3H3,(H,25,26)	MIDBNMYTUQUADA-UHFFFAOYSA-N	50050807	3-Methoxy-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL303631	Endothelin-1 receptor		 0.12								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050807&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9865409	103947900		CHEMBL303631				ZINC13756067	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50082645	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)n1	InChI=1S/C22H20Cl2N2O6/c1-29-17-12-18(30-2)26-21(25-17)32-19(20(27)28)22(31-3,13-4-8-15(23)9-5-13)14-6-10-16(24)11-7-14/h4-12,19H,1-3H3,(H,27,28)	KYFGZGVSIVBTAB-UHFFFAOYSA-N	50050799	3,3-Bis-(4-chloro-phenyl)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-propionic acid::CHEMBL64009	Endothelin-1 receptor		 245								ChEMBL	10.1021/jm960274q	10.7270/Q2G44PDH	8667356			Riechers, H; Albrecht, HP; Amberg, W; Baumann, E; Bernard, H; Bohm, HJ; Klinge, D; Kling, A; Muller, S; Raschack, M; Unger, L; Walker, N; Wernet, W	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050799&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10552683	103947892		CHEMBL64009				ZINC13756028	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095469	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cccc(OC)c1	InChI=1S/C25H22O5/c1-28-20-13-11-19(12-14-20)25(27)22(15-17-7-4-3-5-8-17)23(24(26)30-25)18-9-6-10-21(16-18)29-2/h3-14,16,27H,15H2,1-2H3	GVDXSUKFBRQDFV-UHFFFAOYSA-N	50057157	4-Benzyl-5-hydroxy-3-(3-methoxy-phenyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL274307	Endothelin-1 receptor			 90							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057157&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10501279	103953237		CHEMBL274307				ZINC13761538	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095472	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(cc1)S(C)(=O)=O)c1ccc2OCOc2c1	InChI=1S/C26H22O8S/c1-31-19-8-6-18(7-9-19)26(28)21(13-16-3-10-20(11-4-16)35(2,29)30)24(25(27)34-26)17-5-12-22-23(14-17)33-15-32-22/h3-12,14,28H,13,15H2,1-2H3	IBHRHASLMMYFEZ-UHFFFAOYSA-N	50057160	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methanesulfonyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10661	Endothelin-1 receptor			 4							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057160&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10767505	103953240		CHEMBL10661				ZINC13761482	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095473	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)cc1	InChI=1S/C24H17ClO5/c25-18-9-7-17(8-10-18)24(27)19(12-15-4-2-1-3-5-15)22(23(26)30-24)16-6-11-20-21(13-16)29-14-28-20/h1-11,13,27H,12,14H2	HIOIBSDPMJWBMG-UHFFFAOYSA-N	50034257	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-chloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL267094	Endothelin-1 receptor			 3800							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10070783	103942458		CHEMBL267094				ZINC13740947	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095478	COC(=O)c1cccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)c1	InChI=1S/C27H22O8/c1-31-20-9-7-19(8-10-20)27(30)21(13-16-4-3-5-18(12-16)25(28)32-2)24(26(29)35-27)17-6-11-22-23(14-17)34-15-33-22/h3-12,14,30H,13,15H2,1-2H3	DUQFPDAAARLRLV-UHFFFAOYSA-N	50057163	3-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid methyl ester::CHEMBL11176	Endothelin-1 receptor			 8.5							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057163&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10504689	103953243		CHEMBL11176				ZINC13761490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095482	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)cc1OC)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-17-13-23(33-3)24(34-4)14-22(17)32-2)26(27(29)37-28)16-5-10-21-25(12-16)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	ARCCNAPMMHWOCU-UHFFFAOYSA-N	50057167	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(2,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL275701	Endothelin-1 receptor			 1.8							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057167&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10601668	103953247		CHEMBL275701				ZINC13761514	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095484	COc1ccc(cc1OC)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O7/c1-29-20-11-9-18(14-22(20)30-2)26(28)19(12-16-6-4-3-5-7-16)24(25(27)33-26)17-8-10-21-23(13-17)32-15-31-21/h3-11,13-14,28H,12,15H2,1-2H3	KFPPISQYQPSBMX-UHFFFAOYSA-N	50057168	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dimethoxy-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL10846	Endothelin-1 receptor			 11							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057168&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10647021	103953248		CHEMBL10846				ZINC13761468	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095485	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H20O8/c1-31-19-8-6-18(7-9-19)26(30)20(12-15-3-2-4-17(11-15)24(27)28)23(25(29)34-26)16-5-10-21-22(13-16)33-14-32-21/h2-11,13,30H,12,14H2,1H3,(H,27,28)	SQJQXLIPEOMOPN-UHFFFAOYSA-N	50057170	3-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid::CHEMBL10915	Endothelin-1 receptor			 50							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057170&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10647642	103953250		CHEMBL10915				ZINC13761492	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095492	COc1ccccc1C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-28-20-10-6-5-9-18(20)25(27)19(13-16-7-3-2-4-8-16)23(24(26)31-25)17-11-12-21-22(14-17)30-15-29-21/h2-12,14,27H,13,15H2,1H3	KDCDOLUMTVGNHE-UHFFFAOYSA-N	50057173	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(2-methoxy-phenyl)-5H-furan-2-one::CHEMBL269461	Endothelin-1 receptor			 480							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057173&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10645550	103953253		CHEMBL269461				ZINC13761454	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095495	COc1ccc(cc1)C1(O)OC(=O)C(=C1CC1CCCC1)c1ccc2OCOc2c1	InChI=1S/C24H24O6/c1-27-18-9-7-17(8-10-18)24(26)19(12-15-4-2-3-5-15)22(23(25)30-24)16-6-11-20-21(13-16)29-14-28-20/h6-11,13,15,26H,2-5,12,14H2,1H3	CTANMDRPZQDKDO-UHFFFAOYSA-N	50057175	3-Benzo[1,3]dioxol-5-yl-4-cyclopentylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10843	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057175&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10597575	103953255		CHEMBL10843				ZINC13761530	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095497	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(Cl)c(Cl)c2)cc1	InChI=1S/C25H20Cl2O5/c1-30-18-8-3-15(4-9-18)13-20-23(16-5-12-21(26)22(27)14-16)24(28)32-25(20,29)17-6-10-19(31-2)11-7-17/h3-12,14,29H,13H2,1-2H3	RYEVVTBWAHSOKY-UHFFFAOYSA-N	50034266	3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10996	Endothelin-1 receptor			 170							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10412464	103942467		CHEMBL10996				ZINC13740973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095498	COc1ccc(cc1)C1(OC)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-28-20-11-9-19(10-12-20)26(29-2)21(14-17-6-4-3-5-7-17)24(25(27)32-26)18-8-13-22-23(15-18)31-16-30-22/h3-13,15H,14,16H2,1-2H3	LSQBMBUQIJTXOS-UHFFFAOYSA-N	50057176	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL276173	Endothelin-1 receptor			 300							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057176&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10717504	103953256		CHEMBL276173				ZINC13761554	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095499	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(cc1)-c1ccccc1)c1ccc2OCOc2c1	InChI=1S/C31H24O6/c1-34-25-14-12-24(13-15-25)31(33)26(17-20-7-9-22(10-8-20)21-5-3-2-4-6-21)29(30(32)37-31)23-11-16-27-28(18-23)36-19-35-27/h2-16,18,33H,17,19H2,1H3	PSQUTAPWIOSUQU-UHFFFAOYSA-N	50057177	3-Benzo[1,3]dioxol-5-yl-4-biphenyl-4-ylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11345	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057177&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10815005	103953257		CHEMBL11345				ZINC13761526	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095500	COc1ccc(cc1)C(=O)C(\Cc1ccccc1)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-29-19-10-7-17(8-11-19)24(26)20(13-16-5-3-2-4-6-16)23(25(27)28)18-9-12-21-22(14-18)31-15-30-21/h2-12,14H,13,15H2,1H3,(H,27,28)/p-1/b23-20-	VJWJTNIBNOJJIE-ATJXCDBQSA-M	50057155	(Z)-2-Benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate(2-hydroxy-ethyl)-trimethyl-ammonium;::CHEMBL10801::CHEMBL51530	Endothelin-1 receptor			 49							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057155&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18792235	103953235		CHEMBL10801CHEMBL51530				ZINC03945731	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095501	COc1ccc(cc1C)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-16-12-19(9-11-21(16)29-2)26(28)20(13-17-6-4-3-5-7-17)24(25(27)32-26)18-8-10-22-23(14-18)31-15-30-22/h3-12,14,28H,13,15H2,1-2H3	WWMOPKHFPOIUHU-UHFFFAOYSA-N	50034270	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-3-methyl-phenyl)-5H-furan-2-one::CHEMBL10588	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034270&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10342643	103942471		CHEMBL10588				ZINC13740955	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095502	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C27H24O8/c1-30-19-8-6-18(7-9-19)27(29)20(12-16-4-10-21(31-2)23(13-16)32-3)25(26(28)35-27)17-5-11-22-24(14-17)34-15-33-22/h4-11,13-14,29H,12,15H2,1-3H3	JOFLWUQNEHCQRX-UHFFFAOYSA-N	50057179	3-Benzo[1,3]dioxol-5-yl-4-(3,4-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL268480	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057179&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10790757	103953259		CHEMBL268480				ZINC13761504	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095505	COC(=O)c1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H20O7/c1-30-24(27)17-7-10-19(11-8-17)26(29)20(13-16-5-3-2-4-6-16)23(25(28)33-26)18-9-12-21-22(14-18)32-15-31-21/h2-12,14,29H,13,15H2,1H3	JDCWQSVRRACVNZ-UHFFFAOYSA-N	50057182	4-(4-Benzo[1,3]dioxol-5-yl-3-benzyl-2-hydroxy-5-oxo-2,5-dihydro-furan-2-yl)-benzoic acid methyl ester::CHEMBL10622	Endothelin-1 receptor			 400							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057182&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10718141	103953262		CHEMBL10622				ZINC13761466	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095507	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(OCc2ccccc2)cc1	InChI=1S/C31H24O6/c32-30-29(23-11-16-27-28(18-23)36-20-35-27)26(17-21-7-3-1-4-8-21)31(33,37-30)24-12-14-25(15-13-24)34-19-22-9-5-2-6-10-22/h1-16,18,33H,17,19-20H2	JPQNTLPMEWVANT-UHFFFAOYSA-N	50057159	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-benzyloxy-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL11341	Endothelin-1 receptor			 950							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057159&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10553165	103953239		CHEMBL11341				ZINC13761464	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095514	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OC)c1OC)c1ccc2OCOc2c1	InChI=1S/C27H24O8/c1-30-19-10-8-18(9-11-19)27(29)20(13-17-5-4-6-22(31-2)25(17)32-3)24(26(28)35-27)16-7-12-21-23(14-16)34-15-33-21/h4-12,14,29H,13,15H2,1-3H3	PVBMZCNYYKVYCL-UHFFFAOYSA-N	50057187	3-Benzo[1,3]dioxol-5-yl-4-(2,3-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL276252	Endothelin-1 receptor			 11							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10552548	103953267		CHEMBL276252				ZINC13761500	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095520	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(OC)c(OC)c1OC)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-9-7-18(8-10-19)28(30)20(13-17-6-12-22(32-2)26(34-4)25(17)33-3)24(27(29)37-28)16-5-11-21-23(14-16)36-15-35-21/h5-12,14,30H,13,15H2,1-4H3	NUGYAMLAUIVHKL-UHFFFAOYSA-N	50057190	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(2,3,4-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL274175	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057190&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10791694	103953270		CHEMBL274175				ZINC13761512	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095521	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-28-19-10-8-18(9-11-19)25(27)20(13-16-5-3-2-4-6-16)23(24(26)31-25)17-7-12-21-22(14-17)30-15-29-21/h2-12,14,27H,13,15H2,1H3	JZHLIUOZBXWYGJ-UHFFFAOYSA-N	50034256	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL274383::PD-155080	Endothelin-1 receptor			 7.4							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034256&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11742628	103942457		CHEMBL274383				ZINC13740949	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095526	COc1ccc(cc1)C(=O)C(\Cc1ccc(OC)c(OC)c1OC)=C(/C([O-])=O)c1cc2OCOc2c(OC)c1	InChI=1S/C29H28O10/c1-33-19-9-6-16(7-10-19)25(30)20(12-17-8-11-21(34-2)28(37-5)26(17)36-4)24(29(31)32)18-13-22(35-3)27-23(14-18)38-15-39-27/h6-11,13-14H,12,15H2,1-5H3,(H,31,32)/p-1/b24-20-	DYQYSMVRLLQKSO-GFMRDNFCSA-M	50057164	CHEMBL10862::Sodium; (Z)-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate	Endothelin-1 receptor			 0.34							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057164&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935437	103953244		CHEMBL10862				ZINC26011661	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095527	CCc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O5/c1-2-17-8-11-20(12-9-17)26(28)21(14-18-6-4-3-5-7-18)24(25(27)31-26)19-10-13-22-23(15-19)30-16-29-22/h3-13,15,28H,2,14,16H2,1H3	FWUORMCJYYFPAJ-UHFFFAOYSA-N	50057186	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-ethyl-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL274805	Endothelin-1 receptor			 630							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057186&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10693110	103953266		CHEMBL274805				ZINC13761458	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095529	CC(C)Oc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C27H24O6/c1-17(2)32-21-11-9-20(10-12-21)27(29)22(14-18-6-4-3-5-7-18)25(26(28)33-27)19-8-13-23-24(15-19)31-16-30-23/h3-13,15,17,29H,14,16H2,1-2H3	XTSAGPKOAVSKDU-UHFFFAOYSA-N	50057193	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-isopropoxy-phenyl)-5H-furan-2-one::CHEMBL11064	Endothelin-1 receptor			 1150							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057193&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10694591	103953273		CHEMBL11064				ZINC13761462	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095533	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)ccc1OC)c1ccc2OCOc2c1	InChI=1S/C27H24O8/c1-30-19-7-5-18(6-8-19)27(29)21(13-17-12-20(31-2)9-11-22(17)32-3)25(26(28)35-27)16-4-10-23-24(14-16)34-15-33-23/h4-12,14,29H,13,15H2,1-3H3	CROFEMTXJUXGTE-UHFFFAOYSA-N	50057194	3-Benzo[1,3]dioxol-5-yl-4-(2,5-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL273723	Endothelin-1 receptor			 2.1							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057194&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814440	103953274		CHEMBL273723				ZINC13761502	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095534	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(C)cc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-16-3-5-17(6-4-16)13-21-24(18-7-12-22-23(14-18)31-15-30-22)25(27)32-26(21,28)19-8-10-20(29-2)11-9-19/h3-12,14,28H,13,15H2,1-2H3	SGMHXYMWOLAIMX-UHFFFAOYSA-N	50034265	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-methyl-benzyl)-5H-furan-2-one::CHEMBL10374	Endothelin-1 receptor			 51							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9845562	103942466		CHEMBL10374				ZINC13740961	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095535	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc2OCCOc2c1)c1ccc2OCOc2c1	InChI=1S/C27H22O8/c1-30-19-6-4-18(5-7-19)27(29)20(12-16-2-8-21-23(13-16)32-11-10-31-21)25(26(28)35-27)17-3-9-22-24(14-17)34-15-33-22/h2-9,13-14,29H,10-12,15H2,1H3	LVGJFPBFENMSKI-UHFFFAOYSA-N	50057200	3-Benzo[1,3]dioxol-5-yl-4-(2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10635	Endothelin-1 receptor			 7.5							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057200&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10790686	103953280		CHEMBL10635				ZINC13761510	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095538	COc1cc(cc2OCOc12)C1=C(Cc2ccccc2)C(O)(OC1=O)c1ccc(OC)c(C)c1	InChI=1S/C27H24O7/c1-16-11-19(9-10-21(16)30-2)27(29)20(12-17-7-5-4-6-8-17)24(26(28)34-27)18-13-22(31-3)25-23(14-18)32-15-33-25/h4-11,13-14,29H,12,15H2,1-3H3	PSZTVHNFWZCDLF-UHFFFAOYSA-N	50057199	4-Benzyl-5-hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-3-methyl-phenyl)-5H-furan-2-one::CHEMBL275559	Endothelin-1 receptor			 8.2							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057199&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10766385	103953279		CHEMBL275559				ZINC13761552	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095539	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)c(Cl)c1	InChI=1S/C24H16Cl2O5/c25-18-8-7-16(12-19(18)26)24(28)17(10-14-4-2-1-3-5-14)22(23(27)31-24)15-6-9-20-21(11-15)30-13-29-20/h1-9,11-12,28H,10,13H2	GTADCEYWHLRYOB-UHFFFAOYSA-N	50034260	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dichloro-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL275991	Endothelin-1 receptor			 400							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10027018	103942461		CHEMBL275991				ZINC13740953	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095541	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(cc1)N(C)C)c1ccc2OCOc2c1	InChI=1S/C27H25NO6/c1-28(2)20-9-4-17(5-10-20)14-22-25(18-6-13-23-24(15-18)33-16-32-23)26(29)34-27(22,30)19-7-11-21(31-3)12-8-19/h4-13,15,30H,14,16H2,1-3H3	NGDVYWJMHOBKQV-UHFFFAOYSA-N	50057183	3-Benzo[1,3]dioxol-5-yl-4-(4-dimethylamino-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10948	Endothelin-1 receptor			 28							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057183&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9868822	103953263		CHEMBL10948				ZINC13761478	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095542	COc1ccc(cc1)C(=O)C(\Cc1ccc(OC)c(OC)c1OC)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-32-19-9-5-16(6-10-19)25(29)20(13-18-8-12-22(33-2)27(35-4)26(18)34-3)24(28(30)31)17-7-11-21-23(14-17)37-15-36-21/h5-12,14H,13,15H2,1-4H3,(H,30,31)/p-1/b24-20-	KVMLOIHJNDCBKI-GFMRDNFCSA-M	50057153	CHEMBL10832::Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate	Endothelin-1 receptor			 1.1							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057153&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935436	103953233		CHEMBL10832				ZINC26013421	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095543	OC(=O)c1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H18O7/c26-23(27)16-6-9-18(10-7-16)25(29)19(12-15-4-2-1-3-5-15)22(24(28)32-25)17-8-11-20-21(13-17)31-14-30-20/h1-11,13,29H,12,14H2,(H,26,27)	JMKSBTHBIHNXTG-UHFFFAOYSA-N	50057195	4-(4-Benzo[1,3]dioxol-5-yl-3-benzyl-2-hydroxy-5-oxo-2,5-dihydro-furan-2-yl)-benzoic acid::CHEMBL11174	Endothelin-1 receptor			>25000							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057195&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10670279	103953275		CHEMBL11174				ZINC26015956	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095544	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc(OC)cc1OC	InChI=1S/C26H24O6/c1-29-19-11-9-18(10-12-19)26(28)22(15-17-7-5-4-6-8-17)24(25(27)32-26)21-14-13-20(30-2)16-23(21)31-3/h4-14,16,28H,15H2,1-3H3	IAUHCACBQAIBNK-UHFFFAOYSA-N	50057174	4-Benzyl-3-(2,4-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10808	Endothelin-1 receptor			 300							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057174&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10788853	103953254		CHEMBL10808				ZINC13761540	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095546	CCOc1cc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc(OCC)c1OCC	InChI=1S/C31H32O9/c1-5-35-26-15-19(16-27(36-6-2)29(26)37-7-3)14-23-28(20-8-13-24-25(17-20)39-18-38-24)30(32)40-31(23,33)21-9-11-22(34-4)12-10-21/h8-13,15-17,33H,5-7,14,18H2,1-4H3	NRCLKFNYCQXXAL-UHFFFAOYSA-N	50057169	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-triethoxy-benzyl)-5H-furan-2-one::CHEMBL417067	Endothelin-1 receptor			 0.12							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057169&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10674176	103953249		CHEMBL417067				ZINC26012027	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095547	COc1cc(cc(OC)c1OC)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C27H24O8/c1-30-22-13-18(14-23(31-2)25(22)32-3)27(29)19(11-16-7-5-4-6-8-16)24(26(28)35-27)17-9-10-20-21(12-17)34-15-33-20/h4-10,12-14,29H,11,15H2,1-3H3	SHTFYWSWZGSFTJ-UHFFFAOYSA-N	50057201	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(3,4,5-trimethoxy-phenyl)-5H-furan-2-one::CHEMBL10589	Endothelin-1 receptor			 25							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057201&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10600668	103953281		CHEMBL10589				ZINC13761474	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095548	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1nccc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C28H21NO6/c1-32-20-9-7-19(8-10-20)28(31)22(15-23-21-5-3-2-4-17(21)12-13-29-23)26(27(30)35-28)18-6-11-24-25(14-18)34-16-33-24/h2-14,31H,15-16H2,1H3	AFZSZVWTPJVSMZ-UHFFFAOYSA-N	50057165	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-isoquinolin-1-ylmethyl-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10860	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057165&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10671928	103953245		CHEMBL10860				ZINC13761524	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095549	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C24H18O5/c25-23-22(17-11-12-20-21(14-17)28-15-27-20)19(13-16-7-3-1-4-8-16)24(26,29-23)18-9-5-2-6-10-18/h1-12,14,26H,13,15H2	SDCJODJPKKXXTB-UHFFFAOYSA-N	50034255	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-phenyl-5H-furan-2-one::CHEMBL11131	Endothelin-1 receptor			 600							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034255&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			345351	103942456		CHEMBL11131				ZINC06574969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095550	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(O)cc1)c1ccc2OCOc2c1	InChI=1S/C25H20O7/c1-29-19-9-5-17(6-10-19)25(28)20(12-15-2-7-18(26)8-3-15)23(24(27)32-25)16-4-11-21-22(13-16)31-14-30-21/h2-11,13,26,28H,12,14H2,1H3	PICHQRVDTXJGHA-UHFFFAOYSA-N	50057184	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-hydroxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10744	Endothelin-1 receptor			 8							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057184&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10646372	103953264		CHEMBL10744				ZINC13761476	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095551	COc1ccc(cc1)C1OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O5/c1-27-19-10-7-17(8-11-19)24-20(13-16-5-3-2-4-6-16)23(25(26)30-24)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,24H,13,15H2,1H3	QJPSOSYPFXRAKF-UHFFFAOYSA-N	50057158	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11152	Endothelin-1 receptor			 700							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057158&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10692351	103953238		CHEMBL11152				ZINC13761556	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095554	COc1ccc(cc1C)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-16-10-19(7-9-21(16)32-2)29(31)20(11-17-12-24(33-3)27(35-5)25(13-17)34-4)26(28(30)38-29)18-6-8-22-23(14-18)37-15-36-22/h6-10,12-14,31H,11,15H2,1-5H3	UTGRGVUJLJJKSH-UHFFFAOYSA-N	50057202	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-3-methyl-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL11369	Endothelin-1 receptor			 0.5							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10815823	103953282		CHEMBL11369				ZINC13761550	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095555	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(NC(C)=O)cc1)c1ccc2OCOc2c1	InChI=1S/C27H23NO7/c1-16(29)28-20-8-3-17(4-9-20)13-22-25(18-5-12-23-24(14-18)34-15-33-23)26(30)35-27(22,31)19-6-10-21(32-2)11-7-19/h3-12,14,31H,13,15H2,1-2H3,(H,28,29)	KJNXTLHIZCKQRF-UHFFFAOYSA-N	50057154	CHEMBL10697::N-{4-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-phenyl}-acetamide	Endothelin-1 receptor			 1.2							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057154&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576427	103953234		CHEMBL10697				ZINC13761484	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095558	CCC1=C(C(=O)OC1(O)c1ccc(OC)cc1)c1ccc2OCOc2c1	InChI=1S/C20H18O6/c1-3-15-18(12-4-9-16-17(10-12)25-11-24-16)19(21)26-20(15,22)13-5-7-14(23-2)8-6-13/h4-10,22H,3,11H2,1-2H3	ZIQBXJIFQHHELM-UHFFFAOYSA-N	50057196	3-Benzo[1,3]dioxol-5-yl-4-ethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL273951	Endothelin-1 receptor			 320							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057196&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10665805	103953276		CHEMBL273951				ZINC13761528	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095559	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1ccc2OCOc2c1	InChI=1S/C25H19ClO6/c1-29-19-9-5-17(6-10-19)25(28)20(12-15-2-7-18(26)8-3-15)23(24(27)32-25)16-4-11-21-22(13-16)31-14-30-21/h2-11,13,28H,12,14H2,1H3	BIXNVCGHAZAOLY-UHFFFAOYSA-N	50034264	3-Benzo[1,3]dioxol-5-yl-4-(4-chloro-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10733	Endothelin-1 receptor			 110							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11744509	103942465		CHEMBL10733				ZINC13740957	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095560	COc1cc(cc2OCOc12)C1=C(Cc2cc(OC)c(OC)c(OC)c2)C(O)(OC1=O)c1ccc(OC)c(C)c1	InChI=1S/C30H30O10/c1-16-9-19(7-8-21(16)33-2)30(32)20(10-17-11-22(34-3)27(37-6)23(12-17)35-4)26(29(31)40-30)18-13-24(36-5)28-25(14-18)38-15-39-28/h7-9,11-14,32H,10,15H2,1-6H3	HEEXATKNWQMTKJ-UHFFFAOYSA-N	50057189	5-Hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-3-methyl-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL10854	Endothelin-1 receptor			 0.9							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057189&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10602743	103953269		CHEMBL10854				ZINC26014032	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095561	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc(OC)c(OC)c(OC)c1	InChI=1S/C27H26O7/c1-30-20-12-10-19(11-13-20)27(29)21(14-17-8-6-5-7-9-17)24(26(28)34-27)18-15-22(31-2)25(33-4)23(16-18)32-3/h5-13,15-16,29H,14H2,1-4H3	DNBPCNHUCLIRKO-UHFFFAOYSA-N	50057161	4-Benzyl-5-hydroxy-5-(4-methoxy-phenyl)-3-(3,4,5-trimethoxy-phenyl)-5H-furan-2-one::CHEMBL10819	Endothelin-1 receptor			 1300							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057161&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10552007	103953241		CHEMBL10819				ZINC13761546	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095565	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccnc1)c1ccc2OCOc2c1	InChI=1S/C24H19NO6/c1-28-18-7-5-17(6-8-18)24(27)19(11-15-3-2-10-25-13-15)22(23(26)31-24)16-4-9-20-21(12-16)30-14-29-20/h2-10,12-13,27H,11,14H2,1H3	UWRJUMIPKBRANC-UHFFFAOYSA-N	50057198	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-pyridin-3-ylmethyl-5H-furan-2-one::CHEMBL10910	Endothelin-1 receptor			 40							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057198&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10526002	103953278		CHEMBL10910				ZINC13761522	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095566	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(OC)cc2)cc1	InChI=1S/C26H24O6/c1-29-20-10-4-17(5-11-20)16-23-24(18-6-12-21(30-2)13-7-18)25(27)32-26(23,28)19-8-14-22(31-3)15-9-19/h4-15,28H,16H2,1-3H3	JCPFQTABMZGRMJ-UHFFFAOYSA-N	50034268	5-Hydroxy-4-(4-methoxy-benzyl)-3,5-bis-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11162	Endothelin-1 receptor			 190							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034268&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10410546	103942469		CHEMBL11162				ZINC13740969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095568	COc1ccc(cc1)C1(OC)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-31-20-9-7-19(8-10-20)29(35-5)21(12-17-13-24(32-2)27(34-4)25(14-17)33-3)26(28(30)38-29)18-6-11-22-23(15-18)37-16-36-22/h6-11,13-15H,12,16H2,1-5H3	KKXDITRWMCWOGM-UHFFFAOYSA-N	50057197	3-Benzo[1,3]dioxol-5-yl-5-methoxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL11082	Endothelin-1 receptor			 600							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057197&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10577879	103953277		CHEMBL11082				ZINC13761558	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095569	COc1cccc(c1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O6/c1-28-19-9-5-8-18(14-19)25(27)20(12-16-6-3-2-4-7-16)23(24(26)31-25)17-10-11-21-22(13-17)30-15-29-21/h2-11,13-14,27H,12,15H2,1H3	UEZAHMGOKOCCEP-UHFFFAOYSA-N	50057204	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(3-methoxy-phenyl)-5H-furan-2-one::CHEMBL274857	Endothelin-1 receptor			 500							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057204&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740614	103953284		CHEMBL274857				ZINC13761456	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095571	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OC)c1)c1ccc2OCOc2c1	InChI=1S/C26H22O7/c1-29-19-9-7-18(8-10-19)26(28)21(13-16-4-3-5-20(12-16)30-2)24(25(27)33-26)17-6-11-22-23(14-17)32-15-31-22/h3-12,14,28H,13,15H2,1-2H3	YJGADOCQUFXVMH-UHFFFAOYSA-N	50057192	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(3-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10607	Endothelin-1 receptor			 3							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057192&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10789524	103953272		CHEMBL10607				ZINC13761498	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095572	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(c1)C(F)(F)F)c1ccc2OCOc2c1	InChI=1S/C26H19F3O6/c1-32-19-8-6-17(7-9-19)25(31)20(12-15-3-2-4-18(11-15)26(27,28)29)23(24(30)35-25)16-5-10-21-22(13-16)34-14-33-21/h2-11,13,31H,12,14H2,1H3	YLUYDFCTBUPYGJ-UHFFFAOYSA-N	50057203	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3-trifluoromethyl-benzyl)-5H-furan-2-one::CHEMBL10676	Endothelin-1 receptor			 43							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057203&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9913198	103953283		CHEMBL10676				ZINC13761496	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095573	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor			 1.1							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095574	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc2ccccc2c1)c1ccc2OCOc2c1	InChI=1S/C29H22O6/c1-32-23-11-9-22(10-12-23)29(31)24(15-18-6-7-19-4-2-3-5-20(19)14-18)27(28(30)35-29)21-8-13-25-26(16-21)34-17-33-25/h2-14,16,31H,15,17H2,1H3	IDDGCVGQUZZIPY-UHFFFAOYSA-N	50057211	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-naphthalen-2-ylmethyl-5H-furan-2-one::CHEMBL269453	Endothelin-1 receptor			 14							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057211	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057211&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10742841	103953291		CHEMBL269453				ZINC13761520	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095575	CSc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O5S/c1-31-19-10-8-18(9-11-19)25(27)20(13-16-5-3-2-4-6-16)23(24(26)30-25)17-7-12-21-22(14-17)29-15-28-21/h2-12,14,27H,13,15H2,1H3	BPTJMXBDLHQLJL-UHFFFAOYSA-N	50057151	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-(4-methylsulfanyl-phenyl)-5H-furan-2-one::CHEMBL10911	Endothelin-1 receptor			 170							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057151&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10622616	103953231		CHEMBL10911				ZINC13761460	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095577	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc2OCOc2c(OC)c1	InChI=1S/C26H22O7/c1-29-19-10-8-18(9-11-19)26(28)20(12-16-6-4-3-5-7-16)23(25(27)33-26)17-13-21(30-2)24-22(14-17)31-15-32-24/h3-11,13-14,28H,12,15H2,1-2H3	FZNWHURKGWXPCC-UHFFFAOYSA-N	50057191	4-Benzyl-5-hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10794	Endothelin-1 receptor			 6.7							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057191&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10503525	103953271		CHEMBL10794				ZINC13761548	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095578	COc1ccc(cc1)C(=O)C(\Cc1ccccc1)=C(/C([O-])=O)c1cc2OCOc2c(OC)c1	InChI=1S/C26H22O7/c1-30-19-10-8-17(9-11-19)24(27)20(12-16-6-4-3-5-7-16)23(26(28)29)18-13-21(31-2)25-22(14-18)32-15-33-25/h3-11,13-14H,12,15H2,1-2H3,(H,28,29)/p-1/b23-20-	HKLZPDIAPVJSFU-ATJXCDBQSA-M	50057185	CHEMBL273660::Sodium; (Z)-3-benzyl-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057185&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935440	103953265		CHEMBL273660				ZINC26011632	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095579	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1cc2OCOc2c(OC)c1	InChI=1S/C29H28O10/c1-32-19-8-6-18(7-9-19)29(31)20(10-16-11-21(33-2)26(36-5)22(12-16)34-3)25(28(30)39-29)17-13-23(35-4)27-24(14-17)37-15-38-27/h6-9,11-14,31H,10,15H2,1-5H3	ABTJDYUDDLHWCG-UHFFFAOYSA-N	50057150	5-Hydroxy-3-(7-methoxy-benzo[1,3]dioxol-5-yl)-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL10781	Endothelin-1 receptor			 0.5							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057150&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10530409	103953230		CHEMBL10781				ZINC26011437	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095581	COc1cc(cc2OCOc12)C(\C([O-])=O)=C(/Cc1ccc(OC)c(OC)c1OC)C(=O)c1ccc(OC)c(C)c1	InChI=1S/C30H30O10/c1-16-11-17(7-9-21(16)34-2)26(31)20(12-18-8-10-22(35-3)29(38-6)27(18)37-5)25(30(32)33)19-13-23(36-4)28-24(14-19)39-15-40-28/h7-11,13-14H,12,15H2,1-6H3,(H,32,33)/p-1/b25-20-	ICAHNKLYQDWFQQ-QQTULTPQSA-M	50057178	CHEMBL10847::Sodium; (Z)-2-(7-methoxy-benzo[1,3]dioxol-5-yl)-4-(4-methoxy-3-methyl-phenyl)-4-oxo-3-(2,3,4-trimethoxy-benzyl)-but-2-enoate	Endothelin-1 receptor			 0.78							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057178&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935439	103953258		CHEMBL10847				ZINC26012593	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095582	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C29H22O6/c1-32-22-12-10-21(11-13-22)29(31)24(15-19-7-4-6-18-5-2-3-8-23(18)19)27(28(30)35-29)20-9-14-25-26(16-20)34-17-33-25/h2-14,16,31H,15,17H2,1H3	BEOPICWDIUVLRU-UHFFFAOYSA-N	50057215	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-naphthalen-1-ylmethyl-5H-furan-2-one::CHEMBL269409	Endothelin-1 receptor			 18							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057215&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10647898	103953295		CHEMBL269409				ZINC13761518	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095584	COc1ccc(cc1)C(=O)C(\Cc1ccc(NC(C)=O)cc1)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C27H23NO7/c1-16(29)28-20-8-3-17(4-9-20)13-22(26(30)18-5-10-21(33-2)11-6-18)25(27(31)32)19-7-12-23-24(14-19)35-15-34-23/h3-12,14H,13,15H2,1-2H3,(H,28,29)(H,31,32)/p-1/b25-22-	OCUILRUINFKWQH-LVWGJNHUSA-M	50057213	CHEMBL10905::Potassium; (Z)-3-(4-acetylamino-benzyl)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-but-2-enoate	Endothelin-1 receptor			 4.9							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057213&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935441	103953293		CHEMBL10905				ZINC26015998	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095587	COC(=O)c1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc1	InChI=1S/C27H22O8/c1-31-20-10-8-19(9-11-20)27(30)21(13-16-3-5-17(6-4-16)25(28)32-2)24(26(29)35-27)18-7-12-22-23(14-18)34-15-33-22/h3-12,14,30H,13,15H2,1-2H3	YKHVTFMXBOREDW-UHFFFAOYSA-N	50057180	4-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-benzoic acid methyl ester::CHEMBL417428	Endothelin-1 receptor			 11							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057180&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9934580	103953260		CHEMBL417428				ZINC13761486	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095589	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccccc2)cc1	InChI=1S/C25H22O5/c1-28-20-12-8-17(9-13-20)16-22-23(18-6-4-3-5-7-18)24(26)30-25(22,27)19-10-14-21(29-2)15-11-19/h3-15,27H,16H2,1-2H3	GCLJDQQEPIRTNF-UHFFFAOYSA-N	50034261	5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-phenyl-5H-furan-2-one::CHEMBL10897	Endothelin-1 receptor			 2200							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034261&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10024044	103942462		CHEMBL10897				ZINC13740965	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095591	Cc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C25H20O5/c1-16-7-10-19(11-8-16)25(27)20(13-17-5-3-2-4-6-17)23(24(26)30-25)18-9-12-21-22(14-18)29-15-28-21/h2-12,14,27H,13,15H2,1H3	HUUWRVJBRKRKHX-UHFFFAOYSA-N	50034258	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5-p-tolyl-5H-furan-2-one::CHEMBL273613	Endothelin-1 receptor			 4900							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9865706	103942459		CHEMBL273613				ZINC13740951	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095592	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(SC)cc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6S/c1-29-19-8-6-18(7-9-19)26(28)21(13-16-3-10-20(33-2)11-4-16)24(25(27)32-26)17-5-12-22-23(14-17)31-15-30-22/h3-12,14,28H,13,15H2,1-2H3	PLFIEKUAKHVMIM-UHFFFAOYSA-N	50057207	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-methylsulfanyl-benzyl)-5H-furan-2-one::CHEMBL10636	Endothelin-1 receptor			 3.9							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057207&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10695363	103953287		CHEMBL10636				ZINC13761480	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095598	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc(OC)c(OC)c1	InChI=1S/C26H24O6/c1-29-20-12-10-19(11-13-20)26(28)21(15-17-7-5-4-6-8-17)24(25(27)32-26)18-9-14-22(30-2)23(16-18)31-3/h4-14,16,28H,15H2,1-3H3	LXPHVGHGSNLHAG-UHFFFAOYSA-N	50057172	4-Benzyl-3-(3,4-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10901	Endothelin-1 receptor			 70							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057172&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10765171	103953252		CHEMBL10901				ZINC13761536	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095599	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc2OCOc2c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C27H22O9/c1-30-18-6-4-17(5-7-18)27(29)19(9-15-10-22(31-2)25-23(11-15)34-14-35-25)24(26(28)36-27)16-3-8-20-21(12-16)33-13-32-20/h3-8,10-12,29H,9,13-14H2,1-2H3	DFIYAVVTQXZWPF-UHFFFAOYSA-N	50057188	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11106	Endothelin-1 receptor			 14							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057188&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10505209	103953268		CHEMBL11106				ZINC13761516	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095601	COc1ccc(cc1)C1(O)OC(=O)C(=C1CC1CCCCCC1)c1ccc2OCOc2c1	InChI=1S/C26H28O6/c1-29-20-11-9-19(10-12-20)26(28)21(14-17-6-4-2-3-5-7-17)24(25(27)32-26)18-8-13-22-23(15-18)31-16-30-22/h8-13,15,17,28H,2-7,14,16H2,1H3	VZYMQNGHMAKWDO-UHFFFAOYSA-N	50057162	3-Benzo[1,3]dioxol-5-yl-4-cycloheptylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10919	Endothelin-1 receptor			 35							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057162&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10503067	103953242		CHEMBL10919				ZINC13761534	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095603	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(cc1)[N+]([O-])=O)c1ccc2OCOc2c1	InChI=1S/C25H19NO8/c1-31-19-9-5-17(6-10-19)25(28)20(12-15-2-7-18(8-3-15)26(29)30)23(24(27)34-25)16-4-11-21-22(13-16)33-14-32-21/h2-11,13,28H,12,14H2,1H3	IUBQFXBBEJQVMV-UHFFFAOYSA-N	50057171	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(4-nitro-benzyl)-5H-furan-2-one::CHEMBL10940	Endothelin-1 receptor			 800							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057171&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10623877	103953251		CHEMBL10940				ZINC13761488	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095605	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc2c1CCc1ccccc1C2=O)c1ccc2OCOc2c1	InChI=1S/C34H26O7/c1-38-24-13-11-23(12-14-24)34(37)28(31(33(36)41-34)22-10-16-29-30(18-22)40-19-39-29)17-21-6-4-8-27-25(21)15-9-20-5-2-3-7-26(20)32(27)35/h2-8,10-14,16,18,37H,9,15,17,19H2,1H3	WDPRKEQNBXVDKN-UHFFFAOYSA-N	50057156	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(5-oxo-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-1-ylmethyl)-5H-furan-2-one::CHEMBL276601	Endothelin-1 receptor			 16000							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057156&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44267002	103953236		CHEMBL276601				ZINC26016201	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095607	COc1ccc(cc1C)C(=O)C(\Cc1cc(OC)c(OC)c(OC)c1)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-16-10-19(7-8-21(16)33-2)27(30)20(11-17-12-24(34-3)28(36-5)25(13-17)35-4)26(29(31)32)18-6-9-22-23(14-18)38-15-37-22/h6-10,12-14H,11,15H2,1-5H3,(H,31,32)/p-1/b26-20-	RDVXVKVLWVMYGT-QOMWVZHYSA-M	50057166	CHEMBL10922::Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-3-methyl-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate	Endothelin-1 receptor			 0.98							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057166&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91935438	103953246		CHEMBL10922				ZINC26013399	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095609	COc1ccc(cc1)C1OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O8/c1-30-19-8-5-17(6-9-19)26-20(11-16-12-23(31-2)27(33-4)24(13-16)32-3)25(28(29)36-26)18-7-10-21-22(14-18)35-15-34-21/h5-10,12-14,26H,11,15H2,1-4H3	ZNRFEQPTBFAHSC-UHFFFAOYSA-N	50057208	3-Benzo[1,3]dioxol-5-yl-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL10644	Endothelin-1 receptor			 30							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057208&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9957225	103953288		CHEMBL10644				ZINC13761560	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095610	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(c1)[N+]([O-])=O)c1ccc2OCOc2c1	InChI=1S/C25H19NO8/c1-31-19-8-6-17(7-9-19)25(28)20(12-15-3-2-4-18(11-15)26(29)30)23(24(27)34-25)16-5-10-21-22(13-16)33-14-32-21/h2-11,13,28H,12,14H2,1H3	ZLGDGRLTDMLDDP-UHFFFAOYSA-N	50057214	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3-nitro-benzyl)-5H-furan-2-one::CHEMBL276018	Endothelin-1 receptor			 70							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057214&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11798228	103953294		CHEMBL276018				ZINC13761494	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095611	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(C)cc2)cc1	InChI=1S/C26H24O5/c1-17-4-8-19(9-5-17)24-23(16-18-6-12-21(29-2)13-7-18)26(28,31-25(24)27)20-10-14-22(30-3)15-11-20/h4-15,28H,16H2,1-3H3	OKZRQVZTVLKRLK-UHFFFAOYSA-N	50034262	5-Hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-3-p-tolyl-5H-furan-2-one::CHEMBL10951	Endothelin-1 receptor			 570							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10047521	103942463		CHEMBL10951				ZINC13740971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095612	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc1	InChI=1S/C26H22O7/c1-29-19-8-3-16(4-9-19)13-21-24(17-5-12-22-23(14-17)32-15-31-22)25(27)33-26(21,28)18-6-10-20(30-2)11-7-18/h3-12,14,28H,13,15H2,1-2H3	SUKHVLAHDGZTPC-UHFFFAOYSA-N	50034259	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL11115	Endothelin-1 receptor			 1.8							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034259&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9955200	103942460		CHEMBL11115				ZINC13740959	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095613	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc(OC)ccc1OC	InChI=1S/C26H24O6/c1-29-19-11-9-18(10-12-19)26(28)22(15-17-7-5-4-6-8-17)24(25(27)32-26)21-16-20(30-2)13-14-23(21)31-3/h4-14,16,28H,15H2,1-3H3	BDMQTGZMPJVDBO-UHFFFAOYSA-N	50057152	4-Benzyl-3-(2,5-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL267096	Endothelin-1 receptor			 240							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057152&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10646375	103953232		CHEMBL267096				ZINC13761542	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095614	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(OC)c(C)c1)c1ccc2OCOc2c1	InChI=1S/C27H24O7/c1-16-12-17(4-10-22(16)31-3)13-21-25(18-5-11-23-24(14-18)33-15-32-23)26(28)34-27(21,29)19-6-8-20(30-2)9-7-19/h4-12,14,29H,13,15H2,1-3H3	LCTRHYXOTRTJQR-UHFFFAOYSA-N	50034269	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-(4-methoxy-3-methyl-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10924	Endothelin-1 receptor			 2.4							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034269&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9890440	103942470		CHEMBL10924				ZINC13740963	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095615	COc1ccc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc(Cl)cc2)cc1	InChI=1S/C25H21ClO5/c1-29-20-11-3-16(4-12-20)15-22-23(17-5-9-19(26)10-6-17)24(27)31-25(22,28)18-7-13-21(30-2)14-8-18/h3-14,28H,15H2,1-2H3	RQUIHRSTPLMWSU-UHFFFAOYSA-N	50034254	3-(4-Chloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10648	Endothelin-1 receptor			 700							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034254&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9980487	103942455		CHEMBL10648				ZINC13740967	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095617	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc2OCOc2c1)c1ccc2OCOc2c1	InChI=1S/C26H20O8/c1-29-18-6-4-17(5-7-18)26(28)19(10-15-2-8-20-22(11-15)32-13-30-20)24(25(27)34-26)16-3-9-21-23(12-16)33-14-31-21/h2-9,11-12,28H,10,13-14H2,1H3	KRKNSARESAMDEE-UHFFFAOYSA-N	50057206	3-Benzo[1,3]dioxol-5-yl-4-benzo[1,3]dioxol-5-ylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL276639	Endothelin-1 receptor			 16							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057206&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10671649	103953286		CHEMBL276639				ZINC13761508	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095618	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)cc(OC)c1)c1ccc2OCOc2c1	InChI=1S/C27H24O8/c1-30-19-7-5-18(6-8-19)27(29)22(12-16-10-20(31-2)14-21(11-16)32-3)25(26(28)35-27)17-4-9-23-24(13-17)34-15-33-23/h4-11,13-14,29H,12,15H2,1-3H3	DJUNTHAWPBMJGJ-UHFFFAOYSA-N	50057181	3-Benzo[1,3]dioxol-5-yl-4-(3,5-dimethoxy-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL274359	Endothelin-1 receptor			 1.7							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057181&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10719367	103953261		CHEMBL274359				ZINC13761506	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095621	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1cc(OC)cc(OC)c1	InChI=1S/C26H24O6/c1-29-20-11-9-19(10-12-20)26(28)23(13-17-7-5-4-6-8-17)24(25(27)32-26)18-14-21(30-2)16-22(15-18)31-3/h4-12,14-16,28H,13H2,1-3H3	ZOSIIZNBOBYSGU-UHFFFAOYSA-N	50057205	4-Benzyl-3-(3,5-dimethoxy-phenyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL268754	Endothelin-1 receptor			 46							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057205&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10670372	103953285		CHEMBL268754				ZINC13761544	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095625	OC1(OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc2OCOc2c1	InChI=1S/C25H18O7/c26-24-23(16-6-8-19-21(11-16)30-13-28-19)18(10-15-4-2-1-3-5-15)25(27,32-24)17-7-9-20-22(12-17)31-14-29-20/h1-9,11-12,27H,10,13-14H2	XRNWLGYOIPZNLV-UHFFFAOYSA-N	50057212	3,5-Bis-benzo[1,3]dioxol-5-yl-4-benzyl-5-hydroxy-5H-furan-2-one::CHEMBL417978	Endothelin-1 receptor			 19							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057212&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10765057	103953292		CHEMBL417978				ZINC13761472	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095626	COc1ccc(c(OC)c1)C1(O)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O7/c1-29-18-9-10-19(22(14-18)30-2)26(28)20(12-16-6-4-3-5-7-16)24(25(27)33-26)17-8-11-21-23(13-17)32-15-31-21/h3-11,13-14,28H,12,15H2,1-2H3	MAGGKBPCDJALCG-UHFFFAOYSA-N	50057210	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(2,4-dimethoxy-phenyl)-5-hydroxy-5H-furan-2-one::CHEMBL10834	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057210&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10671036	103953290		CHEMBL10834				ZINC13761470	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095629	COc1ccc(cc1)C1(O)OC(=O)C(=C1CC1CCCCC1)c1ccc2OCOc2c1	InChI=1S/C25H26O6/c1-28-19-10-8-18(9-11-19)25(27)20(13-16-5-3-2-4-6-16)23(24(26)31-25)17-7-12-21-22(14-17)30-15-29-21/h7-12,14,16,27H,2-6,13,15H2,1H3	SXEVCCXWQGAXSQ-UHFFFAOYSA-N	50057209	3-Benzo[1,3]dioxol-5-yl-4-cyclohexylmethyl-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL273948	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057209	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057209&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9932004	103953289		CHEMBL273948				ZINC13761532	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50095630	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(Cl)c(Cl)c1)c1ccc2OCOc2c1	InChI=1S/C25H18Cl2O6/c1-30-17-6-4-16(5-7-17)25(29)18(10-14-2-8-19(26)20(27)11-14)23(24(28)33-25)15-3-9-21-22(12-15)32-13-31-21/h2-9,11-12,29H,10,13H2,1H3	CPXPSOCKTSIDJD-UHFFFAOYSA-N	50057216	3-Benzo[1,3]dioxol-5-yl-4-(3,4-dichloro-benzyl)-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL10926	Endothelin-1 receptor			 150							ChEMBL	10.1021/jm9606507	10.7270/Q27P8XG5	9089328			Patt, WC; Edmunds, JJ; Repine, JT; Berryman, KA; Reisdorph, BR; Lee, C; Plummer, MS; Shahripour, A; Haleen, SJ; Keiser, JA; Flynn, MA; Welch, KM; Reynolds, EE; Rubin, R; Tobias, B; Hallak, H; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057216&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576863	103953296		CHEMBL10926				ZINC13761452	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097503	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc3OCOc3c2)c1Br	InChI=1S/C16H12BrN3O6S2/c1-8-13(17)16(26-19-8)20-28(22,23)12-4-5-27-14(12)15(21)18-9-2-3-10-11(6-9)25-7-24-10/h2-6,20H,7H2,1H3,(H,18,21)	JNCMNPQOJWALQJ-UHFFFAOYSA-N	50058086	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-ylamide::CHEMBL283136	Endothelin-1 receptor			 19							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058086&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814776	103954065		CHEMBL283136				ZINC13815620	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097504	Cc1noc(NS(=O)(=O)c2ccsc2C(C)(O)Cc2ccc3OCOc3c2)c1Cl	InChI=1S/C18H17ClN2O6S2/c1-10-15(19)17(27-20-10)21-29(23,24)14-5-6-28-16(14)18(2,22)8-11-3-4-12-13(7-11)26-9-25-12/h3-7,21-22H,8-9H2,1-2H3	SSUWDCUTKUTXBQ-UHFFFAOYSA-N	50058128	2-(2-Benzo[1,3]dioxol-5-yl-1-hydroxy-1-methyl-ethyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL46195	Endothelin-1 receptor			 22200							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058128&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10647488	103954107		CHEMBL46195				ZINC13815703	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097346	CN(C)C(=O)Cc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C20H19ClN4O7S2/c1-10-17(21)20(32-23-10)24-34(28,29)15-4-5-33-18(15)19(27)22-12-8-14-13(30-9-31-14)6-11(12)7-16(26)25(2)3/h4-6,8,24H,7,9H2,1-3H3,(H,22,27)	NFZNRQSKVNGHOU-UHFFFAOYSA-N	50058077	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-dimethylcarbamoylmethyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL297618	Endothelin-1 receptor			 9.3							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058077&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10119105	103954056		CHEMBL297618				ZINC29414216	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097347	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cccc(O)c2)c1Br	InChI=1S/C15H12BrN3O5S2/c1-8-12(16)15(24-18-8)19-26(22,23)11-5-6-25-13(11)14(21)17-9-3-2-4-10(20)7-9/h2-7,19-20H,1H3,(H,17,21)	KSQKEFQVXCELPS-UHFFFAOYSA-N	50058078	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (3-hydroxy-phenyl)-amide::CHEMBL48024	Endothelin-1 receptor			 146							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058078&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10718688	103954057		CHEMBL48024				ZINC13815636	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097348	COC(=O)c1cc(OC)cc(OC)c1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C19H18ClN3O8S2/c1-9-14(20)18(31-22-9)23-33(26,27)13-5-6-32-16(13)17(24)21-15-11(19(25)30-4)7-10(28-2)8-12(15)29-3/h5-8,23H,1-4H3,(H,21,24)	WGQYSLYCRPURSK-UHFFFAOYSA-N	50058074	2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-3,5-dimethoxy-benzoic acid methyl ester::CHEMBL295632	Endothelin-1 receptor			 549							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058074&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291602	103954053		CHEMBL295632				ZINC29409905	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097353	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2C)c1Cl	InChI=1S/C17H14ClN3O6S2/c1-8-5-11-12(26-7-25-11)6-10(8)19-16(22)15-13(3-4-28-15)29(23,24)21-17-14(18)9(2)20-27-17/h3-6,21H,7H2,1-2H3,(H,19,22)	JGJJUDPFPXBWNF-UHFFFAOYSA-N	50058080	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-methyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL297473	Endothelin-1 receptor			 3							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058080	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058080&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10226215	103954059		CHEMBL297473				ZINC13815783	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097357	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cccc(C)c2)c1Br	InChI=1S/C16H14BrN3O4S2/c1-9-4-3-5-11(8-9)18-15(21)14-12(6-7-25-14)26(22,23)20-16-13(17)10(2)19-24-16/h3-8,20H,1-2H3,(H,18,21)	JWLWWTTYSPSXMJ-UHFFFAOYSA-N	50058083	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid m-tolylamide::CHEMBL48031	Endothelin-1 receptor			 104							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058083	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058083&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10527774	103954062		CHEMBL48031				ZINC13815776	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097361	CC(=O)OCCOc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C20H18ClN3O9S2/c1-10-17(21)20(33-23-10)24-35(27,28)16-3-6-34-18(16)19(26)22-12-7-14-15(32-9-31-14)8-13(12)30-5-4-29-11(2)25/h3,6-8,24H,4-5,9H2,1-2H3,(H,22,26)	YMQODRGSNYOWMG-UHFFFAOYSA-N	50058075	Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzo[1,3]dioxol-5-yloxy)-ethyl ester::CHEMBL296129	Endothelin-1 receptor			 6.1							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058075&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10554539	103954054		CHEMBL296129				ZINC29412298	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097363	CCC(C)c1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1	InChI=1S/C19H20BrN3O4S2/c1-4-11(2)13-5-7-14(8-6-13)21-18(24)17-15(9-10-28-17)29(25,26)23-19-16(20)12(3)22-27-19/h5-11,23H,4H2,1-3H3,(H,21,24)	VMSGLMJNCOIKRS-UHFFFAOYSA-N	50058091	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-sec-butyl-phenyl)-amide::CHEMBL295697	Endothelin-1 receptor			 54							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058091	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058091&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10815167	103954070		CHEMBL295697				ZINC04642479	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097364	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cc2)c1C	InChI=1S/C17H17N3O4S2/c1-10-4-6-13(7-5-10)18-16(21)15-14(8-9-25-15)26(22,23)20-17-11(2)12(3)19-24-17/h4-9,20H,1-3H3,(H,18,21)	IIMOFYDNSGNNBK-UHFFFAOYSA-N	50058081	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolylamide::CHEMBL45456	Endothelin-1 receptor			 32							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058081	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058081&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10548486	103954060		CHEMBL45456				ZINC13815588	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097366	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cccc(c2)C(O)=O)c1Br	InChI=1S/C16H12BrN3O6S2/c1-8-12(17)15(26-19-8)20-28(24,25)11-5-6-27-13(11)14(21)18-10-4-2-3-9(7-10)16(22)23/h2-7,20H,1H3,(H,18,21)(H,22,23)	PZCFZONZHSIXRR-UHFFFAOYSA-N	50058089	3-{[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzoic acid; compound with acetic acid::CHEMBL47008	Endothelin-1 receptor			 62							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058089&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576889	103954068		CHEMBL47008				ZINC13815610	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097367	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)NCc2ccccc2)c1Br	InChI=1S/C16H14BrN3O4S2/c1-10-13(17)16(24-19-10)20-26(22,23)12-7-8-25-14(12)15(21)18-9-11-5-3-2-4-6-11/h2-8,20H,9H2,1H3,(H,18,21)	YERLCYSKOWRFNL-UHFFFAOYSA-N	50058090	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzylamide::CHEMBL417358	Endothelin-1 receptor			 229							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058090&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10766198	103954069		CHEMBL417358				ZINC13815558	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097370	COc1cccc(NCc2sccc2S(=O)(=O)Nc2onc(C)c2Br)c1	InChI=1S/C16H16BrN3O4S2/c1-10-15(17)16(24-19-10)20-26(21,22)14-6-7-25-13(14)9-18-11-4-3-5-12(8-11)23-2/h3-8,18,20H,9H2,1-2H3	HSKJJBDJDFTTFR-UHFFFAOYSA-N	50058085	2-[(3-Methoxy-phenylamino)-methyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide; TFA::CHEMBL416086	Endothelin-1 receptor			 933							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058085&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11798109	103954064		CHEMBL416086				ZINC13815606	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097374	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cc2)c1Cl	InChI=1S/C16H14ClN3O4S2/c1-9-3-5-11(6-4-9)18-15(21)14-12(7-8-25-14)26(22,23)20-16-13(17)10(2)19-24-16/h3-8,20H,1-2H3,(H,18,21)	LONCVVCONRXSBM-UHFFFAOYSA-N	50058095	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolylamide::CHEMBL278114	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058095&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10811595	103954074		CHEMBL278114				ZINC00839629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097376	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cc2)c1Br	InChI=1S/C16H14BrN3O4S2/c1-9-3-5-11(6-4-9)18-15(21)14-12(7-8-25-14)26(22,23)20-16-13(17)10(2)19-24-16/h3-8,20H,1-2H3,(H,18,21)	NTMHYERDLBOXCG-UHFFFAOYSA-N	50058093	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolylamide::CHEMBL296326	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058093&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10599879	103954072		CHEMBL296326				ZINC13815574	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097377	Cc1nnc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)s1	InChI=1S/C12H10ClN5O4S3/c1-5-8(13)11(22-17-5)18-25(20,21)7-3-4-23-9(7)10(19)14-12-16-15-6(2)24-12/h3-4,18H,1-2H3,(H,14,16,19)	YOKLRIXJYHUWAI-UHFFFAOYSA-N	50058098	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (5-methyl-[1,3,4]thiadiazol-2-yl)-amide::CHEMBL297048	Endothelin-1 receptor			 1290							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058098&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10550033	103954077		CHEMBL297048				ZINC13815743	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097379	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2C)c1Br	InChI=1S/C16H14BrN3O4S2/c1-9-5-3-4-6-11(9)18-15(21)14-12(7-8-25-14)26(22,23)20-16-13(17)10(2)19-24-16/h3-8,20H,1-2H3,(H,18,21)	XJFPFBBCTYGHMH-UHFFFAOYSA-N	50058096	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid o-tolylamide::CHEMBL47450	Endothelin-1 receptor			 27							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058096&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10575755	103954075		CHEMBL47450				ZINC13815772	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097380	Cc1noc(NS(=O)(=O)c2ccsc2C(N)=O)c1Br	InChI=1S/C9H8BrN3O4S2/c1-4-6(10)9(17-12-4)13-19(15,16)5-2-3-18-7(5)8(11)14/h2-3,13H,1H3,(H2,11,14)	FSUWQETZHKACGA-UHFFFAOYSA-N	50058094	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid amide::CHEMBL297107	Endothelin-1 receptor			 838.0							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058094&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10546830	103954073		CHEMBL297107				ZINC13815617	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097381	COc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1	InChI=1S/C16H14BrN3O5S2/c1-9-13(17)16(25-19-9)20-27(22,23)12-7-8-26-14(12)15(21)18-10-3-5-11(24-2)6-4-10/h3-8,20H,1-2H3,(H,18,21)	GQNVKBUSESBTBX-UHFFFAOYSA-N	50058072	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-methoxy-phenyl)-amide::CHEMBL296291	Endothelin-1 receptor			 24							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058072	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058072&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576379	103954051		CHEMBL296291				ZINC01540811	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097382	Cc1cc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)no1	InChI=1S/C13H11ClN4O5S2/c1-6-5-9(17-22-6)15-12(19)11-8(3-4-24-11)25(20,21)18-13-10(14)7(2)16-23-13/h3-5,18H,1-2H3,(H,15,17,19)	UUCGTKYPZQVGKK-UHFFFAOYSA-N	50058076	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (5-methyl-isoxazol-3-yl)-amide; TFA::CHEMBL48120	Endothelin-1 receptor			 57							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058076&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10621170	103954055		CHEMBL48120				ZINC13815726	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097384	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cn2)c1Cl	InChI=1S/C15H13ClN4O4S2/c1-8-3-4-11(17-7-8)18-14(21)13-10(5-6-25-13)26(22,23)20-15-12(16)9(2)19-24-15/h3-7,20H,1-2H3,(H,17,18,21)	ISFIWNACPUUPII-UHFFFAOYSA-N	50058100	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (5-methyl-pyridin-2-yl)-amide::CHEMBL45087	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058100&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740439	103954079		CHEMBL45087				ZINC13815769	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097385	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2)c1Br	InChI=1S/C15H12BrN3O4S2/c1-9-12(16)15(23-18-9)19-25(21,22)11-7-8-24-13(11)14(20)17-10-5-3-2-4-6-10/h2-8,19H,1H3,(H,17,20)	MEXIZICSHQFANT-UHFFFAOYSA-N	50058073	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenylamide::CHEMBL45269	Endothelin-1 receptor			 166							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058073&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10503334	103954052		CHEMBL45269				ZINC01540810	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097386	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(=O)[nH]n2)c1Br	InChI=1S/C13H10BrN5O5S2/c1-6-10(14)13(24-18-6)19-26(22,23)7-4-5-25-11(7)12(21)15-8-2-3-9(20)17-16-8/h2-5,19H,1H3,(H,17,20)(H,15,16,21)	LTUFGJPPYKPMHS-UHFFFAOYSA-N	50058101	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-hydroxy-pyridazin-3-yl)-amide; TFA::CHEMBL44615	Endothelin-1 receptor			 65							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445468	103954080		CHEMBL44615				ZINC13815734	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097387	CN(C(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Br)c1ccccc1	InChI=1S/C16H14BrN3O4S2/c1-10-13(17)15(24-18-10)19-26(22,23)12-8-9-25-14(12)16(21)20(2)11-6-4-3-5-7-11/h3-9,19H,1-2H3	CVPJYWMWYDMXMB-UHFFFAOYSA-N	50058082	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid methyl-phenyl-amide; TFA::CHEMBL47536	Endothelin-1 receptor			 1910							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058082	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058082&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10503976	103954061		CHEMBL47536				ZINC13815591	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097388	CC(=O)c1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C19H17N3O7S2/c1-9-10(2)21-29-19(9)22-31(25,26)16-4-5-30-17(16)18(24)20-13-7-15-14(27-8-28-15)6-12(13)11(3)23/h4-7,22H,8H2,1-3H3,(H,20,24)	LTAJIUUAOOWVSJ-UHFFFAOYSA-N	50058102	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-acetyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL295583	Endothelin-1 receptor			 31							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058102&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10552051	103954081		CHEMBL295583				ZINC13815752	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097389	COc1cc(OC)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(c1)C(O)=O	InChI=1S/C18H16ClN3O8S2/c1-8-13(19)17(30-21-8)22-32(26,27)12-4-5-31-15(12)16(23)20-14-10(18(24)25)6-9(28-2)7-11(14)29-3/h4-7,22H,1-3H3,(H,20,23)(H,24,25)	XJXZHZNBOKRBON-UHFFFAOYSA-N	50058087	2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-3,5-dimethoxy-benzoic acid::CHEMBL296074	Endothelin-1 receptor			 1430							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058087	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058087&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291584	103954066		CHEMBL296074				ZINC29413564	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097391	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(cc2)-c2ccccc2)c1Br	InChI=1S/C21H16BrN3O4S2/c1-13-18(22)21(29-24-13)25-31(27,28)17-11-12-30-19(17)20(26)23-16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-12,25H,1H3,(H,23,26)	VANYAUBXJRJUTH-UHFFFAOYSA-N	50058079	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid biphenyl-4-ylamide::CHEMBL44321	Endothelin-1 receptor			 977.0							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058079&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10625738	103954058		CHEMBL44321				ZINC29406664	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097395	COc1cccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)c1	InChI=1S/C16H14BrN3O5S2/c1-9-13(17)16(25-19-9)20-27(22,23)12-6-7-26-14(12)15(21)18-10-4-3-5-11(8-10)24-2/h3-8,20H,1-2H3,(H,18,21)	SYCPGPBCEDENBL-UHFFFAOYSA-N	50058107	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (3-methoxy-phenyl)-amide; TFA::CHEMBL288967	Endothelin-1 receptor			 85							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058107&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576377	103954086		CHEMBL288967				ZINC01540812	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097398	CC(=O)OCCc1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C20H18ClN3O8S2/c1-10-17(21)20(32-23-10)24-34(27,28)16-4-6-33-18(16)19(26)22-13-8-15-14(30-9-31-15)7-12(13)3-5-29-11(2)25/h4,6-8,24H,3,5,9H2,1-2H3,(H,22,26)	AOMQIATVHQSAEZ-UHFFFAOYSA-N	50058099	Acetic acid 2-(6-{[3-(4-chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzo[1,3]dioxol-5-yl)-ethyl ester::CHEMBL296927	Endothelin-1 receptor			 4.5							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058099&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10279940	103954078		CHEMBL296927				ZINC29414186	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097400	COc1cc(OC)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(c1)C#N	InChI=1S/C18H15ClN4O6S2/c1-9-14(19)18(29-22-9)23-31(25,26)13-4-5-30-16(13)17(24)21-15-10(8-20)6-11(27-2)7-12(15)28-3/h4-7,23H,1-3H3,(H,21,24)	GRYXLLNIHXLZBP-UHFFFAOYSA-N	50058105	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-cyano-4,6-dimethoxy-phenyl)-amide::CHEMBL296456	Endothelin-1 receptor			 3.9							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291897	103954084		CHEMBL296456				ZINC29411208	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097401	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2CCCO)c1Cl	InChI=1S/C19H18ClN3O7S2/c1-10-16(20)19(30-22-10)23-32(26,27)15-4-6-31-17(15)18(25)21-12-8-14-13(28-9-29-14)7-11(12)3-2-5-24/h4,6-8,23-24H,2-3,5,9H2,1H3,(H,21,25)	MMTIZYVOCQLCBI-UHFFFAOYSA-N	50058103	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid [6-(3-hydroxy-propyl)-benzo[1,3]dioxol-5-yl]-amide::CHEMBL47620	Endothelin-1 receptor			 6							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058103&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11799541	103954082		CHEMBL47620				ZINC13815823	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097403	CCCCc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1	InChI=1S/C19H20BrN3O4S2/c1-3-4-5-13-6-8-14(9-7-13)21-18(24)17-15(10-11-28-17)29(25,26)23-19-16(20)12(2)22-27-19/h6-11,23H,3-5H2,1-2H3,(H,21,24)	BUPZNIYUBICILZ-UHFFFAOYSA-N	50058110	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-butyl-phenyl)-amide::CHEMBL45760	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058110&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10577255	103954089		CHEMBL45760				ZINC29413214	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097405	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2CNS(C)(=O)=O)c1Cl	InChI=1S/C18H17ClN4O8S3/c1-9-15(19)18(31-22-9)23-34(27,28)14-3-4-32-16(14)17(24)21-11-6-13-12(29-8-30-13)5-10(11)7-20-33(2,25)26/h3-6,20,23H,7-8H2,1-2H3,(H,21,24)	WSEWFQSMWHJQFF-UHFFFAOYSA-N	50058092	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid [6-(methanesulfonylamino-methyl)-benzo[1,3]dioxol-5-yl]-amide; TFA::CHEMBL47828	Endothelin-1 receptor			 6.8							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058092&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10697883	103954071		CHEMBL47828				ZINC29408819	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097406	CCc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1	InChI=1S/C17H16BrN3O4S2/c1-3-11-4-6-12(7-5-11)19-16(22)15-13(8-9-26-15)27(23,24)21-17-14(18)10(2)20-25-17/h4-9,21H,3H2,1-2H3,(H,19,22)	KVRTURHINFWHJV-UHFFFAOYSA-N	50058109	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-ethyl-phenyl)-amide::CHEMBL47418	Endothelin-1 receptor			 17							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058109&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10504542	103954088		CHEMBL47418				ZINC01540813	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097407	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc3OCOc3c2)c1Br	InChI=1S/C16H12BrN3O6S2/c1-8-13(17)16(26-19-8)20-28(22,23)12-4-5-27-14(12)15(21)18-9-2-3-10-11(6-9)25-7-24-10/h2-6,20H,7H2,1H3,(H,18,21)	JNCMNPQOJWALQJ-UHFFFAOYSA-N	50058086	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-ylamide::CHEMBL283136	Endothelin-1 receptor			 19							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058086&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814776	103954065		CHEMBL283136				ZINC13815620	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097410	COc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(C)c1	InChI=1S/C17H16ClN3O5S2/c1-9-8-11(25-3)4-5-12(9)19-16(22)15-13(6-7-27-15)28(23,24)21-17-14(18)10(2)20-26-17/h4-8,21H,1-3H3,(H,19,22)	JAISZXOUESMARL-UHFFFAOYSA-N	50058111	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-methoxy-2-methyl-phenyl)-amide::CHEMBL48134	Endothelin-1 receptor			 2.6							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058111&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10646831	103954090		CHEMBL48134				ZINC00839631	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097415	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2C(O)=O)c1Br	InChI=1S/C16H12BrN3O6S2/c1-8-12(17)15(26-19-8)20-28(24,25)11-6-7-27-13(11)14(21)18-10-5-3-2-4-9(10)16(22)23/h2-7,20H,1H3,(H,18,21)(H,22,23)	ZBFZAVXSCOSZFU-UHFFFAOYSA-N	50058088	2-{[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-benzoic acid::CHEMBL44539	Endothelin-1 receptor			 214							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058088&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576888	103954067		CHEMBL44539				ZINC13815614	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097418	CC(=O)c1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C18H14ClN3O7S2/c1-8-15(19)18(29-21-8)22-31(25,26)14-3-4-30-16(14)17(24)20-11-6-13-12(27-7-28-13)5-10(11)9(2)23/h3-6,22H,7H2,1-2H3,(H,20,24)	RKTQDYUICJAAKQ-UHFFFAOYSA-N	50058115	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-acetyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL283535	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058115&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10696210	103954094		CHEMBL283535				ZINC01893329	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097420	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(cc2)C(C)(C)C)c1Br	InChI=1S/C19H20BrN3O4S2/c1-11-15(20)18(27-22-11)23-29(25,26)14-9-10-28-16(14)17(24)21-13-7-5-12(6-8-13)19(2,3)4/h5-10,23H,1-4H3,(H,21,24)	JZKUOZZZEAJPGF-UHFFFAOYSA-N	50058112	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-tert-butyl-phenyl)-amide::CHEMBL433074	Endothelin-1 receptor			 47							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058112&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10815168	103954091		CHEMBL433074				ZINC13815581	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097422	CC(C)c1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1	InChI=1S/C18H18BrN3O4S2/c1-10(2)12-4-6-13(7-5-12)20-17(23)16-14(8-9-27-16)28(24,25)22-18-15(19)11(3)21-26-18/h4-10,22H,1-3H3,(H,20,23)	BFXDKRQKGCLOJU-UHFFFAOYSA-N	50058104	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-isopropyl-phenyl)-amide::CHEMBL47417	Endothelin-1 receptor			 20							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058104&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10672494	103954083		CHEMBL47417				ZINC13815577	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097424	COc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(OC)c1	InChI=1S/C17H16ClN3O6S2/c1-9-14(18)17(27-20-9)21-29(23,24)13-6-7-28-15(13)16(22)19-11-5-4-10(25-2)8-12(11)26-3/h4-8,21H,1-3H3,(H,19,22)	AWBISQYKDUIJOK-UHFFFAOYSA-N	50058108	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2,4-dimethoxy-phenyl)-amide; compound with acetic acid ethyl ester::CHEMBL43788	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058108&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10575845	103954087		CHEMBL43788				ZINC13815765	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097425	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2C#N)c1Cl	InChI=1S/C17H11ClN4O6S2/c1-8-14(18)17(28-21-8)22-30(24,25)13-2-3-29-15(13)16(23)20-10-5-12-11(26-7-27-12)4-9(10)6-19/h2-5,22H,7H2,1H3,(H,20,23)	SFHTYTXFJBCUIC-UHFFFAOYSA-N	50058106	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-cyano-benzo[1,3]dioxol-5-yl)-amide::CHEMBL19808	Endothelin-1 receptor			 3.4							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058106&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10205245	103954085		CHEMBL19808				ZINC01544684	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097427	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2CC#N)c1Cl	InChI=1S/C18H13ClN4O6S2/c1-9-15(19)18(29-22-9)23-31(25,26)14-3-5-30-16(14)17(24)21-11-7-13-12(27-8-28-13)6-10(11)2-4-20/h3,5-7,23H,2,8H2,1H3,(H,21,24)	HOLYODVKNMQCLH-UHFFFAOYSA-N	50058114	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-cyanomethyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL417719	Endothelin-1 receptor			 3.8							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058114&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10504920	103954093		CHEMBL417719				ZINC13815820	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097429	COc1ccccc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C16H14BrN3O5S2/c1-9-13(17)16(25-19-9)20-27(22,23)12-7-8-26-14(12)15(21)18-10-5-3-4-6-11(10)24-2/h3-8,20H,1-2H3,(H,18,21)	SYCOUEQDKJKTQR-UHFFFAOYSA-N	50058113	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-methoxy-phenyl)-amide::CHEMBL295207	Endothelin-1 receptor			 132							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058113&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10576378	103954092		CHEMBL295207				ZINC13815555	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097431	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2OCCO)c1Cl	InChI=1S/C18H16ClN3O8S2/c1-9-15(19)18(30-21-9)22-32(25,26)14-2-5-31-16(14)17(24)20-10-6-12-13(29-8-28-12)7-11(10)27-4-3-23/h2,5-7,22-23H,3-4,8H2,1H3,(H,20,24)	XLWUWLXWMRPIPP-UHFFFAOYSA-N	50058117	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid [6-(2-hydroxy-ethoxy)-benzo[1,3]dioxol-5-yl]-amide::CHEMBL47604	Endothelin-1 receptor			 5.1							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058117&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10553490	103954096		CHEMBL47604				ZINC13815826	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097433	COc1cc(OC)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(c1)C(N)=O	InChI=1S/C18H17ClN4O7S2/c1-8-13(19)18(30-22-8)23-32(26,27)12-4-5-31-15(12)17(25)21-14-10(16(20)24)6-9(28-2)7-11(14)29-3/h4-7,23H,1-3H3,(H2,20,24)(H,21,25)	NJFUCLJMONYZBN-UHFFFAOYSA-N	50058116	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-carbamoyl-4,6-dimethoxy-phenyl)-amide::CHEMBL297215	Endothelin-1 receptor			 10.8							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058116&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291583	103954095		CHEMBL297215				ZINC29409234	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097434	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2CCO)c1Cl	InChI=1S/C18H16ClN3O7S2/c1-9-15(19)18(29-21-9)22-31(25,26)14-3-5-30-16(14)17(24)20-11-7-13-12(27-8-28-13)6-10(11)2-4-23/h3,5-7,22-23H,2,4,8H2,1H3,(H,20,24)	VESFHNMVCVQILM-UHFFFAOYSA-N	50058097	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid [6-(2-hydroxy-ethyl)-benzo[1,3]dioxol-5-yl]-amide::CHEMBL295588	Endothelin-1 receptor			 5.6							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058097&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10140965	103954076		CHEMBL295588				ZINC13815803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097436	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cc2O)c1Cl	InChI=1S/C16H14ClN3O5S2/c1-8-3-4-10(11(21)7-8)18-15(22)14-12(5-6-26-14)27(23,24)20-16-13(17)9(2)19-25-16/h3-7,20-21H,1-2H3,(H,18,22)	BYVAPURPCHCYSP-UHFFFAOYSA-N	50058084	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-hydroxy-4-methyl-phenyl)-amide::CHEMBL47827	Endothelin-1 receptor			 6.6							ChEMBL	10.1021/jm9608366	10.7270/Q25T3JKT	9171877			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Castillo, RS	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058084	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058084&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10137382	103954063		CHEMBL47827				ZINC13815779	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097439	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cc2)c1Cl	InChI=1S/C16H14ClN3O4S2/c1-9-3-5-11(6-4-9)18-15(21)14-12(7-8-25-14)26(22,23)20-16-13(17)10(2)19-24-16/h3-8,20H,1-2H3,(H,18,21)	LONCVVCONRXSBM-UHFFFAOYSA-N	50058095	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolylamide::CHEMBL278114	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058095&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10811595	103954074		CHEMBL278114				ZINC00839629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097440	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc(C)cc(C)c2)c1Cl	InChI=1S/C18H17ClN2O4S2/c1-10-6-11(2)8-13(7-10)9-14(22)17-15(4-5-26-17)27(23,24)21-18-16(19)12(3)20-25-18/h4-8,21H,9H2,1-3H3	CPFCIOFJGQIPIZ-UHFFFAOYSA-N	50058119	2-[2-(3,5-Dimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL47765	Endothelin-1 receptor			 45							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058119&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10741025	103954098		CHEMBL47765				ZINC13815806	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097442	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc3OCOc3c2)c1Br	InChI=1S/C17H13BrN2O6S2/c1-9-15(18)17(26-19-9)20-28(22,23)14-4-5-27-16(14)11(21)6-10-2-3-12-13(7-10)25-8-24-12/h2-5,7,20H,6,8H2,1H3	YBFXNLMUNIECJZ-UHFFFAOYSA-N	50058121	2-(2-Benzo[1,3]dioxol-5-yl-acetyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL47706	Endothelin-1 receptor			 14							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058121&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814746	103954100		CHEMBL47706				ZINC13815644	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097443	CN(C)C(Cc1ccc2OCOc2c1)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C19H20ClN3O5S2/c1-11-17(20)19(28-21-11)22-30(24,25)16-6-7-29-18(16)13(23(2)3)8-12-4-5-14-15(9-12)27-10-26-14/h4-7,9,13,22H,8,10H2,1-3H3	VOXFYDGCNHZJNG-UHFFFAOYSA-N	50058118	2-(2-Benzo[1,3]dioxol-5-yl-1-dimethylamino-ethyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; TFA::CHEMBL416453	Endothelin-1 receptor			 21000							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058118&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10742968	103954097		CHEMBL416453				ZINC13815714	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097444	COc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(C)c1	InChI=1S/C17H16ClN3O5S2/c1-9-8-11(25-3)4-5-12(9)19-16(22)15-13(6-7-27-15)28(23,24)21-17-14(18)10(2)20-26-17/h4-8,21H,1-3H3,(H,19,22)	JAISZXOUESMARL-UHFFFAOYSA-N	50058111	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-methoxy-2-methyl-phenyl)-amide::CHEMBL48134	Endothelin-1 receptor			 2.6							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058111&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10646831	103954090		CHEMBL48134				ZINC00839631	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097446	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)NC(=O)c2ccc3OCOc3c2)c1Br	InChI=1S/C17H12BrN3O7S2/c1-8-13(18)17(28-20-8)21-30(24,25)12-4-5-29-14(12)16(23)19-15(22)9-2-3-10-11(6-9)27-7-26-10/h2-6,21H,7H2,1H3,(H,19,22,23)	JHZBVAHDLOSSCU-UHFFFAOYSA-N	50058123	Benzo[1,3]dioxole-5-carboxylic acid [3-(4-bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amide::CHEMBL297599	Endothelin-1 receptor			 887.0							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058123&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10839533	103954102		CHEMBL297599				ZINC29406468	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097448	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc3OCOc3c2)c1Cl	InChI=1S/C17H13ClN2O6S2/c1-9-15(18)17(26-19-9)20-28(22,23)14-4-5-27-16(14)11(21)6-10-2-3-12-13(7-10)25-8-24-12/h2-5,7,20H,6,8H2,1H3	GQABMKHWSKPQNS-UHFFFAOYSA-N	50058125	2-(2-Benzo[1,3]dioxol-5-yl-acetyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL282470	Endothelin-1 receptor			 18							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058125&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10138169	103954104		CHEMBL282470				ZINC00601928	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097452	Cc1noc(NS(=O)(=O)c2ccsc2C(O)Cc2ccc3OCOc3c2)c1Cl	InChI=1S/C17H15ClN2O6S2/c1-9-15(18)17(26-19-9)20-28(22,23)14-4-5-27-16(14)11(21)6-10-2-3-12-13(7-10)25-8-24-12/h2-5,7,11,20-21H,6,8H2,1H3	GGJUDPCTFYBUCN-UHFFFAOYSA-N	50058129	2-(2-Benzo[1,3]dioxol-5-yl-1-hydroxy-ethyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; compound with acetic acid ethyl ester::CHEMBL297557	Endothelin-1 receptor			 56							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058129&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11797486	103954108		CHEMBL297557				ZINC13815679	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097454	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)c2ccc3OCOc3c2)c1Br	InChI=1S/C16H11BrN2O6S2/c1-8-13(17)16(25-18-8)19-27(21,22)12-4-5-26-15(12)14(20)9-2-3-10-11(6-9)24-7-23-10/h2-6,19H,7H2,1H3	GEBAVJXLKVTPEZ-UHFFFAOYSA-N	50058130	2-(Benzo[1,3]dioxole-5-carbonyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide; compound with acetic acid ethyl ester::CHEMBL46357	Endothelin-1 receptor			 2000							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058130&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10528383	103954109		CHEMBL46357				ZINC13815632	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097456	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1C	InChI=1S/C19H18N2O6S2/c1-10-6-15-16(26-9-25-15)8-13(10)7-14(22)18-17(4-5-28-18)29(23,24)21-19-11(2)12(3)20-27-19/h4-6,8,21H,7,9H2,1-3H3	ZKAHRYLIFLDFJH-UHFFFAOYSA-N	50058132	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL20168	Endothelin-1 receptor			 3.3							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058132&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10274552	103954111		CHEMBL20168				ZINC13815848	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097459	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C#N)c1Cl	InChI=1S/C18H12ClN3O6S2/c1-9-16(19)18(28-21-9)22-30(24,25)15-2-3-29-17(15)12(23)4-10-5-13-14(27-8-26-13)6-11(10)7-20/h2-3,5-6,22H,4,8H2,1H3	OZRQEMUTNMRJTM-UHFFFAOYSA-N	50058133	2-[2-(6-Cyano-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; compound with acetonitrile::CHEMBL295557	Endothelin-1 receptor			 1.3							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058133&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814036	103954112		CHEMBL295557				ZINC13815829	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097460	COc1cccc(CC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c1	InChI=1S/C17H15ClN2O5S2/c1-10-15(18)17(25-19-10)20-27(22,23)14-6-7-26-16(14)13(21)9-11-4-3-5-12(8-11)24-2/h3-8,20H,9H2,1-2H3	JLOVRXYLWREQNE-UHFFFAOYSA-N	50058136	2-[2-(3-Methoxy-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL297679	Endothelin-1 receptor			 30							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058136&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10622380	103954115		CHEMBL297679				ZINC29412783	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097461	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc(C)ccc2C)c1Cl	InChI=1S/C18H17ClN2O4S2/c1-10-4-5-11(2)13(8-10)9-14(22)17-15(6-7-26-17)27(23,24)21-18-16(19)12(3)20-25-18/h4-8,21H,9H2,1-3H3	UMEIPNHTSHCQOX-UHFFFAOYSA-N	50058124	2-[2-(2,5-Dimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL47424	Endothelin-1 receptor			 7.2							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058124&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10224228	103954103		CHEMBL47424				ZINC13815811	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097464	COc1cc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(cc1OC)C#N	InChI=1S/C18H15ClN4O6S2/c1-9-15(19)18(29-22-9)23-31(25,26)14-4-5-30-16(14)17(24)21-11-7-13(28-3)12(27-2)6-10(11)8-20/h4-7,23H,1-3H3,(H,21,24)	DDLQURLFWCNWJP-UHFFFAOYSA-N	50058120	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-cyano-4,5-dimethoxy-phenyl)-amide::CHEMBL44544	Endothelin-1 receptor			 3.9							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058120&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9956918	103954099		CHEMBL44544				ZINC01893333	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097465	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2)c1C	InChI=1S/C18H18N2O4S2/c1-11-4-6-14(7-5-11)10-15(21)17-16(8-9-25-17)26(22,23)20-18-12(2)13(3)19-24-18/h4-9,20H,10H2,1-3H3	BGVMHOXNOKQCIL-UHFFFAOYSA-N	50058137	2-(2-p-Tolyl-acetyl)-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL45875	Endothelin-1 receptor			 27							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058137&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10715441	103954116		CHEMBL45875				ZINC13815756	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097469	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc3OCOc3c2)c1C	InChI=1S/C18H16N2O6S2/c1-10-11(2)19-26-18(10)20-28(22,23)16-5-6-27-17(16)13(21)7-12-3-4-14-15(8-12)25-9-24-14/h3-6,8,20H,7,9H2,1-2H3	VQFMOPYTWFMRLA-UHFFFAOYSA-N	50058139	2-(2-Benzo[1,3]dioxol-5-yl-acetyl)-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL298203	Endothelin-1 receptor			 27							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058139&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10502226	103954118		CHEMBL298203				ZINC13815760	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097470	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)N2CCN(Cc3ccc4OCOc4c3)CC2)c1Cl	InChI=1S/C21H21ClN4O6S2/c1-13-18(22)20(32-23-13)24-34(28,29)17-4-9-33-19(17)21(27)26-7-5-25(6-8-26)11-14-2-3-15-16(10-14)31-12-30-15/h2-4,9-10,24H,5-8,11-12H2,1H3	NVIPEHOVDZROBC-UHFFFAOYSA-N	50058142	2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazine-1-carbonyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL296427	Endothelin-1 receptor			 19600							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058142&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10554085	103954121		CHEMBL296427				ZINC29413682	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097471	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)C(C#N)c2ccc3OCOc3c2)c1Cl	InChI=1S/C18H12ClN3O6S2/c1-9-15(19)18(28-21-9)22-30(24,25)14-4-5-29-17(14)16(23)11(7-20)10-2-3-12-13(6-10)27-8-26-12/h2-6,11,22H,8H2,1H3	FZGJAAGAWQAEIB-UHFFFAOYSA-N	50058135	2-(2-Benzo[1,3]dioxol-5-yl-2-cyano-acetyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; TFA::CHEMBL48448	Endothelin-1 receptor			 2100							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058135&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10719007	103954114		CHEMBL48448				ZINC13815669	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097472	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2C)c1C	InChI=1S/C19H20N2O4S2/c1-11-5-6-15(12(2)9-11)10-16(22)18-17(7-8-26-18)27(23,24)21-19-13(3)14(4)20-25-19/h5-9,21H,10H2,1-4H3	SKSAMLPLLXHKDC-UHFFFAOYSA-N	50058141	2-[2-(2,4-Dimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL47915	Endothelin-1 receptor			 2.7							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058141&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10525281	103954120		CHEMBL47915				ZINC13815788	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097473	Cc1onc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl	InChI=1S/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)27-20-18/h3-5,7H,6,8H2,1-2H3,(H,20,21)	FUWNXAGLKRZJPK-UHFFFAOYSA-N	50058138	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-5-methyl-isoxazol-3-yl)-amide::CHEMBL297783	Endothelin-1 receptor			 0.63							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058138&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10503921	103954117		CHEMBL297783				ZINC29408365	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097475	COc1ccc(CC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)cc1	InChI=1S/C17H15ClN2O5S2/c1-10-15(18)17(25-19-10)20-27(22,23)14-7-8-26-16(14)13(21)9-11-3-5-12(24-2)6-4-11/h3-8,20H,9H2,1-2H3	BRLOQACEPRWZNR-UHFFFAOYSA-N	50058145	2-[2-(4-Methoxy-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; compound with acetic acid ethyl ester::CHEMBL432109	Endothelin-1 receptor			 43							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058145&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10502577	103954124		CHEMBL432109				ZINC29410855	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097477	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2C)c1Br	InChI=1S/C18H17BrN2O4S2/c1-10-4-5-13(11(2)8-10)9-14(22)17-15(6-7-26-17)27(23,24)21-18-16(19)12(3)20-25-18/h4-8,21H,9H2,1-3H3	QMGUTDDCUVERFO-UHFFFAOYSA-N	50058143	2-[2-(2,4-Dimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL413093	Endothelin-1 receptor			 0.76							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058143&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10648006	103954122		CHEMBL413093				ZINC13815796	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097478	Cc1noc(NS(=O)(=O)c2ccsc2NC(=O)Nc2ccc3OCOc3c2)c1Br	InChI=1S/C16H13BrN4O6S2/c1-8-13(17)14(27-20-8)21-29(23,24)12-4-5-28-15(12)19-16(22)18-9-2-3-10-11(6-9)26-7-25-10/h2-6,21H,7H2,1H3,(H2,18,19,22)	PTJMLGSZIHLGQN-UHFFFAOYSA-N	50058122	2-(3-Benzo[1,3]dioxol-5-yl-ureido)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL45723	Endothelin-1 receptor			 574							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058122&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10649086	103954101		CHEMBL45723				ZINC13815656	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097479	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl	InChI=1S/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)20-27-18/h3-5,7,21H,6,8H2,1-2H3	PHWXUGHIIBDVKD-UHFFFAOYSA-N	50058126	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide (Sitaxsentan)::2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-5-methyl-benzoic acid isopropyl ester::CHEMBL282724::Sitaxentan	Endothelin-1 receptor		 0.43								ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058126&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			216235	103954105		CHEMBL282724	DB06268	3950		ZINC01481831	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097480	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc3OCOc3c2C)c1Cl	InChI=1S/C17H14ClN3O6S2/c1-8-10(3-4-11-14(8)26-7-25-11)19-16(22)15-12(5-6-28-15)29(23,24)21-17-13(18)9(2)20-27-17/h3-6,21H,7H2,1-2H3,(H,19,22)	NZCBNXIFYOIDAA-UHFFFAOYSA-N	50058134	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-methyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL45296	Endothelin-1 receptor			 3							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058134&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291255	103954113		CHEMBL45296				ZINC29404537	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097483	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc3OCOc3c2C#N)c1Cl	InChI=1S/C17H11ClN4O6S2/c1-8-13(18)17(28-21-8)22-30(24,25)12-4-5-29-15(12)16(23)20-10-2-3-11-14(9(10)6-19)27-7-26-11/h2-5,22H,7H2,1H3,(H,20,23)	LAJWTDLCTDQOJG-UHFFFAOYSA-N	50058146	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-cyano-benzo[1,3]dioxol-5-yl)-amide::CHEMBL47404	Endothelin-1 receptor			 3.4							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058146&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291575	103954125		CHEMBL47404				ZINC29411073	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097484	Cc1noc(NS(=O)(=O)c2ccsc2C(Cc2ccc3OCOc3c2)N=O)c1Cl	InChI=1S/C17H14ClN3O6S2/c1-9-15(18)17(27-20-9)21-29(23,24)14-4-5-28-16(14)11(19-22)6-10-2-3-12-13(7-10)26-8-25-12/h2-5,7,11,21H,6,8H2,1H3	UHWSBKQVRQYUKF-UHFFFAOYSA-N	50058127	2-{2-Benzo[1,3]dioxol-5-yl-1-[(Z)-hydroxyimino]-ethyl}-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide; compound with acetic acid ethyl ester::CHEMBL45351	Endothelin-1 receptor			 1100							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058127&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			54354114	103954106		CHEMBL45351				ZINC13815682	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097494	CC(=O)c1c2OCOc2ccc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C18H14ClN3O7S2/c1-8-14(19)18(29-21-8)22-31(25,26)12-5-6-30-16(12)17(24)20-10-3-4-11-15(28-7-27-11)13(10)9(2)23/h3-6,22H,7H2,1-2H3,(H,20,24)	LDBREVXSXRQLLE-UHFFFAOYSA-N	50058148	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (4-acetyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL45160	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058148&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44291884	103954127		CHEMBL45160				ZINC29404807	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097495	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2C)c1Cl	InChI=1S/C18H17ClN2O4S2/c1-10-4-5-13(11(2)8-10)9-14(22)17-15(6-7-26-17)27(23,24)21-18-16(19)12(3)20-25-18/h4-8,21H,9H2,1-3H3	CVKQSYMFVKELBA-UHFFFAOYSA-N	50058144	2-[2-(2,4-Dimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL445101	Endothelin-1 receptor			 0.97							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058144	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058144&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10788494	103954123		CHEMBL445101				ZINC13815792	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097496	Cc1noc(NS(=O)(=O)c2ccsc2C2(Cc3ccc4OCOc4c3)OCCO2)c1Cl	InChI=1S/C19H17ClN2O7S2/c1-11-16(20)18(29-21-11)22-31(23,24)15-4-7-30-17(15)19(27-5-6-28-19)9-12-2-3-13-14(8-12)26-10-25-13/h2-4,7-8,22H,5-6,9-10H2,1H3	GPXLRTHWGLZAPY-UHFFFAOYSA-N	50058131	2-(2-Benzo[1,3]dioxol-5-ylmethyl-[1,3]dioxolan-2-yl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL47383	Endothelin-1 receptor			 123							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058131&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814743	103954110		CHEMBL47383				ZINC13815707	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097497	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc(C)cc2)c1Br	InChI=1S/C17H15BrN2O4S2/c1-10-3-5-12(6-4-10)9-13(21)16-14(7-8-25-16)26(22,23)20-17-15(18)11(2)19-24-17/h3-8,20H,9H2,1-2H3	RWXQRDXNKDBDOX-UHFFFAOYSA-N	50058140	2-(2-p-Tolyl-acetyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL295477	Endothelin-1 receptor			 20							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058140&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10695071	103954119		CHEMBL295477				ZINC13815697	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50097499	Cc1noc(NS(=O)(=O)c2ccsc2NC(=O)Oc2ccc3OCOc3c2)c1Br	InChI=1S/C16H12BrN3O7S2/c1-8-13(17)14(27-19-8)20-29(22,23)12-4-5-28-15(12)18-16(21)26-9-2-3-10-11(6-9)25-7-24-10/h2-6,20H,7H2,1H3,(H,18,21)	IXEOGBXRZGGWAW-UHFFFAOYSA-N	50058147	CHEMBL45872::[3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophen-2-yl]-carbamic acid benzo[1,3]dioxol-5-yl ester	Endothelin-1 receptor			 88							ChEMBL	10.1021/jm9700068	10.7270/Q2222SWV	9171878			Wu, C; Chan, MF; Stavros, F; Raju, B; Okun, I; Mong, S; Keller, KM; Brock, T; Kogan, TP; Dixon, RA	ImmunoPharmaceutics Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058147&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10696788	103954126		CHEMBL45872				ZINC13815647	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103181	CCCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H39FN2O7S/c1-4-6-7-15-40(35,36)32(12-5-2)14-13-31-18-22(20-8-11-25-26(17-20)39-19-38-25)27(29(33)34)28(31)21-9-10-24(37-3)23(30)16-21/h8-11,16-17,22,27-28H,4-7,12-15,18-19H2,1-3H3,(H,33,34)/t22-,27-,28+/m1/s1	JVWVTPZZEHLARL-OFEZKSIWSA-N	50061074	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(pentane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid::A-182086::CHEMBL111277	Endothelin-1 receptor			 0.48							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061074&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9916235	103956661		CHEMBL111277				ZINC03936863	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103193	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m1/s1	MOTJMGVDPWRKOC-QPVYNBJUSA-N	50051007	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::A-127722::CHEMBL9194	Endothelin-1 receptor			 0.034							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			159594	103948098		CHEMBL9194				ZINC03812144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103206	CCCc1cc(ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C28H29NO8S/c1-4-5-19-14-21(28(31)32)9-12-23(19)37-26(20-8-13-24-25(15-20)36-16-35-24)27(30)29-38(33,34)22-10-6-18(7-11-22)17(2)3/h6-15,17,26H,4-5,16H2,1-3H3,(H,29,30)(H,31,32)	JPPYWKVKLSBQJM-UHFFFAOYSA-N	50050964	4-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethoxy]-3-propyl-benzoic acid::CHEMBL8978::L-754142	Endothelin-1 receptor			 0.26							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050964&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9894460	103948055		CHEMBL8978				ZINC25993182	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103234	CCCN(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1)S(=O)(=O)CCCCl	InChI=1S/C27H34ClFN2O7S/c1-3-10-31(39(34,35)13-4-9-28)12-11-30-16-20(18-5-8-23-24(15-18)38-17-37-23)25(27(32)33)26(30)19-6-7-22(36-2)21(29)14-19/h5-8,14-15,20,25-26H,3-4,9-13,16-17H2,1-2H3,(H,32,33)/t20-,25-,26+/m1/s1	IPZKGERDMRMXJO-VANUSSGQSA-N	50061086	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(3-chloro-propane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL325581	Endothelin-1 receptor			 0.07							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061086&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10603409	103956673		CHEMBL325581				ZINC26947207	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103244	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCCO)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H30O8/c1-3-11-34-19-6-7-20-22(14-19)27(21-8-5-18(33-2)15-24(21)35-12-10-30)28(29(31)32)26(20)17-4-9-23-25(13-17)37-16-36-23/h4-9,13-15,26-28,30H,3,10-12,16H2,1-2H3,(H,31,32)/t26-,27+,28+/m0/s1	GLCKXJLCYIJMRB-UPRLRBBYSA-N	50061077	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy-ethoxy)-4-methoxy-phenyl]-5-propoxy-indan-2-carboxylic acid::CHEMBL431651::Enrasentan::SB 217242::SB-217242	Endothelin-1 receptor		 1.1								ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061077&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			178103	103956664		CHEMBL431651				ZINC03825437	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103255	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-3-10-35-18-6-7-19-21(12-18)27(20-8-5-17(34-2)13-23(20)36-14-25(30)31)28(29(32)33)26(19)16-4-9-22-24(11-16)38-15-37-22/h4-9,11-13,26-28H,3,10,14-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27+,28+/m0/s1	UUAVCCWBNUITBB-UPRLRBBYSA-N	50041617	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid::1-benzo[d][1,3]dioxol-5-ylmethyl-3-(2-carboxymethoxy-4-methoxyphenyl)-5-propoxy-(1R,3S)-2,3-dihydro-1H-2-indenecarboxylic acid::CHEMBL8823::SB 209670::SB-209670	Endothelin-1 receptor		 0.2								ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			108002	103973307		CHEMBL8823		3528		ZINC01536124	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103263	CCCN(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1)S(=O)(=O)CCCC(F)(F)F	InChI=1S/C28H34F4N2O7S/c1-3-10-34(42(37,38)13-4-9-28(30,31)32)12-11-33-16-20(18-5-8-23-24(15-18)41-17-40-23)25(27(35)36)26(33)19-6-7-22(39-2)21(29)14-19/h5-8,14-15,20,25-26H,3-4,9-13,16-17H2,1-2H3,(H,35,36)/t20-,25-,26+/m1/s1	BMNFTWGABWKVKN-VANUSSGQSA-N	50061078	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[propyl-(4,4,4-trifluoro-butane-1-sulfonyl)-amino]-ethyl}-pyrrolidine-3-carboxylic acid::CHEMBL419367	Endothelin-1 receptor			 1.66							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061078&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10651488	103956665		CHEMBL419367				ZINC26952128	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103267	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor		 6.5								ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103269	CCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H37FN2O7S/c1-4-6-14-39(34,35)31(11-5-2)13-12-30-17-21(19-7-10-24-25(16-19)38-18-37-24)26(28(32)33)27(30)20-8-9-23(36-3)22(29)15-20/h7-10,15-16,21,26-27H,4-6,11-14,17-18H2,1-3H3,(H,32,33)/t21-,26-,27+/m1/s1	SISHUQWGICPIJE-ZFWHIUCFSA-N	50061096	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[(butane-1-sulfonyl)-propyl-amino]-ethyl}-2-(3-fluoro-4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL323464	Endothelin-1 receptor			 0.044							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061096&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10187997	103956683		CHEMBL323464				ZINC26954881	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50103279	CCCCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H41FN2O7S/c1-4-6-7-8-16-41(36,37)33(13-5-2)15-14-32-19-23(21-9-12-26-27(18-21)40-20-39-26)28(30(34)35)29(32)22-10-11-25(38-3)24(31)17-22/h9-12,17-18,23,28-29H,4-8,13-16,19-20H2,1-3H3,(H,34,35)/t23-,28-,29+/m1/s1	WELUHUKTVXHVBY-ZPJFYFFZSA-N	50061085	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(hexane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid::CHEMBL109644	Endothelin-1 receptor			 0.077							ChEMBL	10.1021/jm970101g	10.7270/Q2C24VJR	9379441			Jae, HS; Winn, M; Dixon, DB; Marsh, KC; Nguyen, B; Opgenorth, TJ; von Geldern, TW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061085&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10210629	103956672		CHEMBL109644				ZINC26973882	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114180	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCO)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34)	LFWCJABOXHSRGC-UHFFFAOYSA-N	50066370	5-Methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(2H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL109648::clazosentan	Endothelin-1 receptor		 0.13								ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066370&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6433095	103961012		CHEMBL109648				ZINC26973408	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114189	COc1ccc(cc1)C(=O)C(\Cc1cc(OC)c(OC)c(OC)c1)=C(/C([O-])=O)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-32-19-8-5-17(6-9-19)26(29)20(11-16-12-23(33-2)27(35-4)24(13-16)34-3)25(28(30)31)18-7-10-21-22(14-18)37-15-36-21/h5-10,12-14H,11,15H2,1-4H3,(H,30,31)/p-1/b25-20-	OFCTYBMKKTVKCR-QQTULTPQSA-M	50034263	CHEMBL25438::PD-156707::Sodium; (Z)-2-benzo[1,3]dioxol-5-yl-4-(4-methoxy-phenyl)-4-oxo-3-(3,4,5-trimethoxy-benzyl)-but-2-enoate	Endothelin-1 receptor		 0.17								ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91929183	103942464		CHEMBL25438				ZINC03945732	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114192	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)\C=C/C)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H44N2O5/c1-6-9-14-30(15-10-7-2)26(32)19-31-18-22(21-11-12-24-25(16-21)36-20-35-24)27(28(33)34)23(31)17-29(4,5)13-8-3/h8,11-13,16,22-23,27H,6-7,9-10,14-15,17-20H2,1-5H3,(H,33,34)/b13-8-/t22-,23+,27-/m1/s1	GRLXMEBTWXGKTK-XNAUMBEWSA-N	50066372	(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-pyrrolidine-3-carboxylic acid::CHEMBL323951	Endothelin-1 receptor			 1							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066372&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44340049	103961014		CHEMBL323951				ZINC26981806	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114220	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CCc1ccccn1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H39N3O5/c1-3-5-15-31(16-6-4-2)27(33)19-32-18-23(21-10-13-25-26(17-21)37-20-36-25)28(29(34)35)24(32)12-11-22-9-7-8-14-30-22/h7-10,13-14,17,23-24,28H,3-6,11-12,15-16,18-20H2,1-2H3,(H,34,35)/t23-,24+,28-/m1/s1	FIVLYOIAUYHSKL-FMGHJNRGSA-N	50066389	(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2-pyridin-2-yl-ethyl)-pyrrolidine-3-carboxylic acid::CHEMBL109778	Endothelin-1 receptor			 0.29							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066389&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870959	103961031		CHEMBL109778				ZINC13780910	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114224	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CCn1cccn1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H38N4O5/c1-3-5-12-29(13-6-4-2)25(32)18-30-17-21(20-8-9-23-24(16-20)36-19-35-23)26(27(33)34)22(30)10-15-31-14-7-11-28-31/h7-9,11,14,16,21-22,26H,3-6,10,12-13,15,17-19H2,1-2H3,(H,33,34)/t21-,22+,26-/m1/s1	DOMNHAGPHWGKAM-TVZXLZGTSA-N	50066400	(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2-pyrazol-1-yl-ethyl)-pyrrolidine-3-carboxylic acid::CHEMBL322537	Endothelin-1 receptor			 1.06							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066400&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10553384	103961042		CHEMBL322537				ZINC13780911	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114240	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H46N2O5/c1-6-9-14-30(15-10-7-2)26(32)19-31-18-22(21-11-12-24-25(16-21)36-20-35-24)27(28(33)34)23(31)17-29(4,5)13-8-3/h11-12,16,22-23,27H,6-10,13-15,17-20H2,1-5H3,(H,33,34)/t22-,23+,27-/m1/s1	ONQFGCOKSYLREQ-QSEAXJEQSA-N	50066405	(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-pyrrolidine-3-carboxylic acid::CHEMBL432974	Endothelin-1 receptor			 0.29							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066405&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10278777	103961047		CHEMBL432974				ZINC13780886	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114255	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CCN1CCCC1=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H41N3O6/c1-3-5-12-29(13-6-4-2)26(33)18-31-17-21(20-9-10-23-24(16-20)37-19-36-23)27(28(34)35)22(31)11-15-30-14-7-8-25(30)32/h9-10,16,21-22,27H,3-8,11-15,17-19H2,1-2H3,(H,34,35)/t21-,22+,27-/m1/s1	IWEQMCSDVPZVMA-UMTXDNHDSA-N	50066379	(2S,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-[2-(2-oxo-pyrrolidin-1-yl)-ethyl]-pyrrolidine-3-carboxylic acid::CHEMBL110053	Endothelin-1 receptor			 0.17							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066379&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9806559	103961021		CHEMBL110053				ZINC13780912	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114272	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2c1)c1ccc(OC)cc1OCCO)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H30O8/c1-3-11-34-19-6-7-20-22(14-19)27(21-8-5-18(33-2)15-24(21)35-12-10-30)28(29(31)32)26(20)17-4-9-23-25(13-17)37-16-36-23/h4-9,13-15,26-28,30H,3,10-12,16H2,1-2H3,(H,31,32)/t26-,27+,28+/m0/s1	GLCKXJLCYIJMRB-UPRLRBBYSA-N	50061077	(1S,2R,3S)-1-Benzo[1,3]dioxol-5-yl-3-[2-(2-hydroxy-ethoxy)-4-methoxy-phenyl]-5-propoxy-indan-2-carboxylic acid::CHEMBL431651::Enrasentan::SB 217242::SB-217242	Endothelin-1 receptor		 1.1								ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061077&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			178103	103956664		CHEMBL431651				ZINC03825437	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114274	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1cc2OCOc2c(OC)c1	InChI=1S/C30H48N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h15-16,22-23,27H,7-14,17-20H2,1-6H3,(H,34,35)/t22-,23+,27-/m1/s1	OAEWNSKRLBVVBV-QSEAXJEQSA-N	50066391	(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::CHEMBL111612	Endothelin-1 receptor			 24900							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066391&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915028	103961033		CHEMBL111612				ZINC04394021	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114278	Cc1noc(NS(=O)(=O)c2sccc2C(=O)Cc2cc3OCOc3cc2C)c1Cl	InChI=1S/C18H15ClN2O6S2/c1-9-5-14-15(26-8-25-14)7-11(9)6-13(22)12-3-4-28-18(12)29(23,24)21-17-16(19)10(2)20-27-17/h3-5,7,21H,6,8H2,1-2H3	SWOBCLGSVXXLQF-UHFFFAOYSA-N	50066398	3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-2-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL326059	Endothelin-1 receptor		 0.43								ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066398&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44339756	103961040		CHEMBL326059				ZINC26978973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114279	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)\C=C/C)C(O)=O)c1cc2OCOc2c(OC)c1	InChI=1S/C30H46N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h9,12,15-16,22-23,27H,7-8,10-11,13-14,17-20H2,1-6H3,(H,34,35)/b12-9-/t22-,23+,27-/m1/s1	GHDYDXZRKIXRDK-RDXXDGPGSA-N	50066374	(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-((Z)-2,2-dimethyl-pent-3-enyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::CHEMBL109926	Endothelin-1 receptor			 0.29							ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066374&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44339655	103961016		CHEMBL109926				ZINC26971123	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50114282	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor		 48								ChEMBL	10.1021/jm980217s	10.7270/Q20Z72D4	9703472			Liu, G; Henry, KJ; Szczepankiewicz, BG; Winn, M; Kozmina, NS; Boyd, SA; Wasicak, J; von Geldern, TW; Wu-Wong, JR; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123352	CN([C@H](Cc1ccc(cc1)-c1ccno1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NS(=O)(=O)c1ccccc1)C(=O)c1cc(C)cc(C)c1	InChI=1S/C39H37N5O6S/c1-25-19-26(2)21-29(20-25)39(47)44(3)35(22-27-13-15-28(16-14-27)36-17-18-41-50-36)38(46)42-34(23-30-24-40-33-12-8-7-11-32(30)33)37(45)43-51(48,49)31-9-5-4-6-10-31/h4-21,24,34-35,40H,22-23H2,1-3H3,(H,42,46)(H,43,45)/t34-,35+/m0/s1	MMVFGIYZPKSYRV-OIDHKYIRSA-N	50071421	CHEMBL310920::N-[(R)-1-[(S)-2-Benzenesulfonylamino-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 2.3								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071421&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311915	103965174		CHEMBL310920				ZINC26379483	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123362	C\C=C\S(=O)(=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C36H37N5O6S/c1-5-16-48(45,46)40-34(42)31(21-28-22-37-30-9-7-6-8-29(28)30)39-35(43)32(41(4)36(44)27-18-23(2)17-24(3)19-27)20-25-10-12-26(13-11-25)33-14-15-38-47-33/h5-19,22,31-32,37H,20-21H2,1-4H3,(H,39,43)(H,40,42)/b16-5+/t31-,32+/m0/s1	KOWYKBJZTIDYKI-NWNLOUMPSA-N	50071428	CHEMBL307471::N-[(R)-1-{(S)-1-(1H-Indol-3-ylmethyl)-2-oxo-2-[((E)-prop-1-ene)-1-sulfonylamino]-ethylcarbamoyl}-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 3.9								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071428&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311726	103965181		CHEMBL307471				ZINC26378630	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123363	CCCS(=O)(=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C36H39N5O6S/c1-5-16-48(45,46)40-34(42)31(21-28-22-37-30-9-7-6-8-29(28)30)39-35(43)32(41(4)36(44)27-18-23(2)17-24(3)19-27)20-25-10-12-26(13-11-25)33-14-15-38-47-33/h6-15,17-19,22,31-32,37H,5,16,20-21H2,1-4H3,(H,39,43)(H,40,42)/t31-,32+/m0/s1	HUDYDAYXYKCRPT-AJQTZOPKSA-N	50071420	CHEMBL72348::N-[(R)-1-[(S)-1-(1H-Indol-3-ylmethyl)-2-oxo-2-(propane-1-sulfonylamino)-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 2.2								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071420&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311727	103965173		CHEMBL72348				ZINC26378633	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123364	CN([C@H](Cc1ccc(cc1)-c1ccccn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C35H34N4O4/c1-22-16-23(2)18-26(17-22)34(41)39(3)32(19-24-11-13-25(14-12-24)29-9-6-7-15-36-29)33(40)38-31(35(42)43)20-27-21-37-30-10-5-4-8-28(27)30/h4-18,21,31-32,37H,19-20H2,1-3H3,(H,38,40)(H,42,43)/t31-,32+/m0/s1	CUQQKEAZMNXDAZ-AJQTZOPKSA-N	50071429	(S)-2-[(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-(4-pyridin-2-yl-phenyl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL70310	Endothelin-1 receptor		 2300								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071429&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311698	103965182		CHEMBL70310				ZINC26295908	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123365	CN([C@H](Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C30H31N3O4/c1-19-13-20(2)15-22(14-19)29(35)33(3)27(16-21-9-5-4-6-10-21)28(34)32-26(30(36)37)17-23-18-31-25-12-8-7-11-24(23)25/h4-15,18,26-27,31H,16-17H2,1-3H3,(H,32,34)(H,36,37)/t26-,27+/m0/s1	JFNANCYIHVAEQV-RRPNLBNLSA-N	50071431	(S)-2-{(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-phenyl-propionylamino}-3-(1H-indol-3-yl)-propionic acid::CHEMBL439759	Endothelin-1 receptor		 11000								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071431&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9848710	103965184		CHEMBL439759				ZINC26377198	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123366	CN([C@H](Cc1ccc(cc1)-c1cccs1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C34H33N3O4S/c1-21-15-22(2)17-25(16-21)33(39)37(3)30(18-23-10-12-24(13-11-23)31-9-6-14-42-31)32(38)36-29(34(40)41)19-26-20-35-28-8-5-4-7-27(26)28/h4-17,20,29-30,35H,18-19H2,1-3H3,(H,36,38)(H,40,41)/t29-,30+/m0/s1	CFTTVXIBXXPWEU-XZWHSSHBSA-N	50071432	(S)-2-[(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-(4-thiophen-2-yl-phenyl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL307470	Endothelin-1 receptor		 87								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071432&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311852	103965185		CHEMBL307470				ZINC26378617	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123370	CN([C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C36H35N3O4/c1-23-17-24(2)19-28(18-23)35(41)39(3)33(20-25-13-15-27(16-14-25)26-9-5-4-6-10-26)34(40)38-32(36(42)43)21-29-22-37-31-12-8-7-11-30(29)31/h4-19,22,32-33,37H,20-21H2,1-3H3,(H,38,40)(H,42,43)/t32-,33+/m0/s1	UZDORQWMYRRLQV-JHOUSYSJSA-N	50071433	(S)-2-{(R)-3-Biphenyl-4-yl-2-[(3,5-dimethyl-benzoyl)-methyl-amino]-propionylamino}-3-(1H-indol-3-yl)-propionic acid::CHEMBL72410	Endothelin-1 receptor		 440								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071433&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	D2U	6K1Q	5311192	103965186		CHEMBL72410		3887		ZINC01891205	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123372	CCCCS(=O)(=O)NC(=O)C(CC(C)C)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C32H42N4O6S/c1-7-8-15-43(40,41)35-30(37)27(16-21(2)3)34-31(38)28(36(6)32(39)26-18-22(4)17-23(5)19-26)20-24-9-11-25(12-10-24)29-13-14-33-42-29/h9-14,17-19,21,27-28H,7-8,15-16,20H2,1-6H3,(H,34,38)(H,35,37)/t27?,28-/m1/s1	IAHNMFPHUACREU-PLYLYKGUSA-N	50071434	CHEMBL72217::N-[(R)-1-[1-(Butane-1-sulfonylaminocarbonyl)-3-methyl-butylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 8								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071434&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311763	103965187		CHEMBL72217				ZINC26378208	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123373	CCOCCS(=O)(=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C37H41N5O7S/c1-5-48-16-17-50(46,47)41-35(43)32(22-29-23-38-31-9-7-6-8-30(29)31)40-36(44)33(42(4)37(45)28-19-24(2)18-25(3)20-28)21-26-10-12-27(13-11-26)34-14-15-39-49-34/h6-15,18-20,23,32-33,38H,5,16-17,21-22H2,1-4H3,(H,40,44)(H,41,43)/t32-,33+/m0/s1	HVBUELUOUQXXRH-JHOUSYSJSA-N	50071423	CHEMBL72924::N-[(R)-1-[(S)-2-(2-Ethoxy-ethanesulfonylamino)-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 6								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071423&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311803	103965176		CHEMBL72924				ZINC26378452	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123377	CN([C@H](Cc1ccc(cc1)-c1ccsc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C34H33N3O4S/c1-21-14-22(2)16-26(15-21)33(39)37(3)31(17-23-8-10-24(11-9-23)25-12-13-42-20-25)32(38)36-30(34(40)41)18-27-19-35-29-7-5-4-6-28(27)29/h4-16,19-20,30-31,35H,17-18H2,1-3H3,(H,36,38)(H,40,41)/t30-,31+/m0/s1	PZBNHZOXFOMEDO-IOWSJCHKSA-N	50071435	(S)-2-[(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-(4-thiophen-3-yl-phenyl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL305462	Endothelin-1 receptor		 54								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311700	103965188		CHEMBL305462				ZINC26293799	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123378	CN([C@H](Cc1ccc(cc1)-c1ccno1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C33H32N4O5/c1-20-14-21(2)16-24(15-20)32(39)37(3)29(17-22-8-10-23(11-9-22)30-12-13-35-42-30)31(38)36-28(33(40)41)18-25-19-34-27-7-5-4-6-26(25)27/h4-16,19,28-29,34H,17-18H2,1-3H3,(H,36,38)(H,40,41)/t28-,29+/m0/s1	UVTGPXVPTNTUDR-URLMMPGGSA-N	50071438	(S)-2-[(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-(4-isoxazol-5-yl-phenyl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL433106	Endothelin-1 receptor		 45								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071438&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311701	103965191		CHEMBL433106				ZINC26296490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123379	CCS(=O)(=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C35H37N5O6S/c1-5-47(44,45)39-33(41)30(20-27-21-36-29-9-7-6-8-28(27)29)38-34(42)31(40(4)35(43)26-17-22(2)16-23(3)18-26)19-24-10-12-25(13-11-24)32-14-15-37-46-32/h6-18,21,30-31,36H,5,19-20H2,1-4H3,(H,38,42)(H,39,41)/t30-,31+/m0/s1	LGRQZNNALZAMDJ-IOWSJCHKSA-N	50071430	CHEMBL73373::N-[(R)-1-[(S)-2-Ethanesulfonylamino-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 5.3								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071430&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311838	103965183		CHEMBL73373				ZINC26377824	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123380	CCCCS(=O)(=O)NC(=O)C(NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)CC	InChI=1S/C32H42N4O6S/c1-7-9-16-43(40,41)35-31(38)29(23(5)8-2)34-30(37)27(36(6)32(39)26-18-21(3)17-22(4)19-26)20-24-10-12-25(13-11-24)28-14-15-33-42-28/h10-15,17-19,23,27,29H,7-9,16,20H2,1-6H3,(H,34,37)(H,35,38)/t23?,27-,29?/m1/s1	FYULQKSAMXDPLJ-IPEXIJNSSA-N	50071422	CHEMBL73042::N-[(R)-1-[1-(Butane-1-sulfonylaminocarbonyl)-2-methyl-butylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 6.9								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071422&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311989	103965175		CHEMBL73042				ZINC26378943	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123381	CN([C@H](Cc1ccc(cc1)-c1ccno1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NS(=O)(=O)CC=C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C36H37N5O6S/c1-5-16-48(45,46)40-34(42)31(21-28-22-37-30-9-7-6-8-29(28)30)39-35(43)32(41(4)36(44)27-18-23(2)17-24(3)19-27)20-25-10-12-26(13-11-25)33-14-15-38-47-33/h5-15,17-19,22,31-32,37H,1,16,20-21H2,2-4H3,(H,39,43)(H,40,42)/t31-,32+/m0/s1	VLHPYESMRDUJNS-AJQTZOPKSA-N	50071437	CHEMBL308102::N-[(R)-1-[(S)-1-(1H-Indol-3-ylmethyl)-2-oxo-2-(prop-2-ene-1-sulfonylamino)-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 0.890000								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071437&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311692	103965190		CHEMBL308102				ZINC03942084	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123383	CN([C@H](Cc1ccc(cc1)-c1ccon1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C33H32N4O5/c1-20-14-21(2)16-24(15-20)32(39)37(3)30(17-22-8-10-23(11-9-22)27-12-13-42-36-27)31(38)35-29(33(40)41)18-25-19-34-28-7-5-4-6-26(25)28/h4-16,19,29-30,34H,17-18H2,1-3H3,(H,35,38)(H,40,41)/t29-,30+/m0/s1	ZHGGJHSZAGTHLS-XZWHSSHBSA-N	50071427	(S)-2-[(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-(4-isoxazol-3-yl-phenyl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL73697	Endothelin-1 receptor		 130								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071427&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311851	103965180		CHEMBL73697				ZINC26378338	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123385	CCCCS(=O)(=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C37H41N5O6S/c1-5-6-17-49(46,47)41-35(43)32(22-29-23-38-31-10-8-7-9-30(29)31)40-36(44)33(42(4)37(45)28-19-24(2)18-25(3)20-28)21-26-11-13-27(14-12-26)34-15-16-39-48-34/h7-16,18-20,23,32-33,38H,5-6,17,21-22H2,1-4H3,(H,40,44)(H,41,43)/t32-,33+/m0/s1	XBKVYIJFYBIMJN-JHOUSYSJSA-N	50071436	CHEMBL306950::N-[(R)-1-[(S)-2-(Butane-1-sulfonylamino)-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 2.9								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071436&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311804	103965189		CHEMBL306950				ZINC03942095	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123387	CN([C@H](Cc1ccc(cc1)-c1ccno1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NS(=O)(=O)Cc1ccccc1)C(=O)c1cc(C)cc(C)c1	InChI=1S/C40H39N5O6S/c1-26-19-27(2)21-31(20-26)40(48)45(3)36(22-28-13-15-30(16-14-28)37-17-18-42-51-37)39(47)43-35(23-32-24-41-34-12-8-7-11-33(32)34)38(46)44-52(49,50)25-29-9-5-4-6-10-29/h4-21,24,35-36,41H,22-23,25H2,1-3H3,(H,43,47)(H,44,46)/t35-,36+/m0/s1	XRUKXLWYVUMZLF-MPQUPPDSSA-N	50071443	CHEMBL308269::N-[(R)-1-[(S)-1-(1H-Indol-3-ylmethyl)-2-oxo-2-phenylmethanesulfonylamino-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 5.4								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071443	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071443&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311850	103965196		CHEMBL308269				ZINC26377843	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123388	CCCCS(=O)(=O)NC(=O)C(CC)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C30H38N4O6S/c1-6-8-15-41(38,39)33-28(35)25(7-2)32-29(36)26(34(5)30(37)24-17-20(3)16-21(4)18-24)19-22-9-11-23(12-10-22)27-13-14-31-40-27/h9-14,16-18,25-26H,6-8,15,19H2,1-5H3,(H,32,36)(H,33,35)/t25?,26-/m1/s1	MWHGEJXLFJLVHX-FXDYGKIASA-N	50071426	CHEMBL73835::N-[(R)-1-[1-(Butane-1-sulfonylaminocarbonyl)-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 5.5								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071426&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311773	103965179		CHEMBL73835				ZINC26295081	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123391	CN([C@H](Cc1ccc(cc1)-c1ccco1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C34H33N3O5/c1-21-15-22(2)17-25(16-21)33(39)37(3)30(18-23-10-12-24(13-11-23)31-9-6-14-42-31)32(38)36-29(34(40)41)19-26-20-35-28-8-5-4-7-27(26)28/h4-17,20,29-30,35H,18-19H2,1-3H3,(H,36,38)(H,40,41)/t29-,30+/m0/s1	RDVHLMJRZJBHMF-XZWHSSHBSA-N	50071441	(S)-2-[(R)-2-[(3,5-Dimethyl-benzoyl)-methyl-amino]-3-(4-furan-2-yl-phenyl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid::CHEMBL70686	Endothelin-1 receptor		 250								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071441&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311699	103965194		CHEMBL70686				ZINC26293788	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123393	CCCCS(=O)(=O)NC(=O)C(Cc1ccc2ccccc2c1)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C39H42N4O6S/c1-5-6-19-50(47,48)42-37(44)34(24-29-13-14-30-9-7-8-10-32(30)23-29)41-38(45)35(43(4)39(46)33-21-26(2)20-27(3)22-33)25-28-11-15-31(16-12-28)36-17-18-40-49-36/h7-18,20-23,34-35H,5-6,19,24-25H2,1-4H3,(H,41,45)(H,42,44)/t34?,35-/m1/s1	KBYIOWQONLGJJU-ICBMVRCQSA-N	50071440	CHEMBL307384::N-[(R)-1-[2-(Butane-1-sulfonylamino)-1-naphthalen-2-ylmethyl-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 3.1								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071440&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311849	103965193		CHEMBL307384				ZINC26377377	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123394	CCCCS(=O)(=O)NC(=O)C(CCSC)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C31H40N4O6S2/c1-6-7-16-43(39,40)34-29(36)26(13-15-42-5)33-30(37)27(35(4)31(38)25-18-21(2)17-22(3)19-25)20-23-8-10-24(11-9-23)28-12-14-32-41-28/h8-12,14,17-19,26-27H,6-7,13,15-16,20H2,1-5H3,(H,33,37)(H,34,36)/t26?,27-/m1/s1	GJEGFKNDKHXDSQ-SSYAZFEXSA-N	50071444	CHEMBL307045::N-[(R)-1-[1-(Butane-1-sulfonylaminocarbonyl)-3-methylsulfanyl-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 5.2								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071444&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311772	103965197		CHEMBL307045				ZINC26295073	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123395	CC(C)S(=O)(=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C36H39N5O6S/c1-22(2)48(45,46)40-34(42)31(20-28-21-37-30-9-7-6-8-29(28)30)39-35(43)32(41(5)36(44)27-17-23(3)16-24(4)18-27)19-25-10-12-26(13-11-25)33-14-15-38-47-33/h6-18,21-22,31-32,37H,19-20H2,1-5H3,(H,39,43)(H,40,42)/t31-,32+/m0/s1	CIMUQXQFDACEAW-AJQTZOPKSA-N	50071439	CHEMBL73000::N-[(R)-1-[(S)-1-(1H-Indol-3-ylmethyl)-2-oxo-2-(propane-2-sulfonylamino)-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 10								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071439&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311805	103965192		CHEMBL73000				ZINC26379115	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123396	CCCCS(=O)(=O)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)C	InChI=1S/C31H40N4O6S/c1-7-8-15-42(39,40)34-30(37)28(20(2)3)33-29(36)26(35(6)31(38)25-17-21(4)16-22(5)18-25)19-23-9-11-24(12-10-23)27-13-14-32-41-27/h9-14,16-18,20,26,28H,7-8,15,19H2,1-6H3,(H,33,36)(H,34,37)/t26-,28+/m1/s1	IFLIQLQVUMXNFU-IAPPQJPRSA-N	50071425	CHEMBL311854::N-[(R)-1-[(S)-1-(Butane-1-sulfonylaminocarbonyl)-2-methyl-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 1.8								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071425&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9938533	103965178		CHEMBL311854				ZINC03942097	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123397	CN([C@H](Cc1ccc(cc1)-c1ccno1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NS(=O)(=O)C=C)C(=O)c1cc(C)cc(C)c1	InChI=1S/C35H35N5O6S/c1-5-47(44,45)39-33(41)30(20-27-21-36-29-9-7-6-8-28(27)29)38-34(42)31(40(4)35(43)26-17-22(2)16-23(3)18-26)19-24-10-12-25(13-11-24)32-14-15-37-46-32/h5-18,21,30-31,36H,1,19-20H2,2-4H3,(H,38,42)(H,39,41)/t30-,31+/m0/s1	CSBNIDOCJNQVQX-IOWSJCHKSA-N	50071445	CHEMBL310039::N-[(R)-1-[(S)-2-Ethenesulfonylamino-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 1.9								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071445&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311728	103965198		CHEMBL310039				ZINC26378892	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123398	CCCCS(=O)(=O)NC(=O)C(NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C1CCCCC1	InChI=1S/C34H44N4O6S/c1-5-6-18-45(42,43)37-33(40)31(27-10-8-7-9-11-27)36-32(39)29(38(4)34(41)28-20-23(2)19-24(3)21-28)22-25-12-14-26(15-13-25)30-16-17-35-44-30/h12-17,19-21,27,29,31H,5-11,18,22H2,1-4H3,(H,36,39)(H,37,40)/t29-,31?/m1/s1	QLRLGCLZQTWZOK-FDOABKJOSA-N	50071442	CHEMBL72358::N-[(R)-1-[2-(Butane-1-sulfonylamino)-1-cyclohexyl-2-oxo-ethylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 8.6								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071442&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311873	103965195		CHEMBL72358				ZINC26375859	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123400	CCCCS(=O)(=O)NC(=O)C(NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)O	InChI=1S/C30H38N4O7S/c1-6-7-14-42(39,40)33-29(37)27(21(4)35)32-28(36)25(34(5)30(38)24-16-19(2)15-20(3)17-24)18-22-8-10-23(11-9-22)26-12-13-31-41-26/h8-13,15-17,21,25,27,35H,6-7,14,18H2,1-5H3,(H,32,36)(H,33,37)/t21?,25-,27?/m1/s1	WETZUHODUGXVKY-PYLWXJQRSA-N	50071424	CHEMBL263301::N-[(R)-1-[1-(Butane-1-sulfonylaminocarbonyl)-2-hydroxy-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 9.1								ChEMBL	10.1016/s0960-894x(98)00387-4	10.7270/Q2BC3XQ7	9873521			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Trueh, T; Pitterna, T; Iwasaki, G; Oda, K; Yamamura, T; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071424&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311858	103965177		CHEMBL263301				ZINC26376609	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123403	CCCCS(=O)(=O)NC(=O)[C@H](NC(=O)[C@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)C	InChI=1S/C31H40N4O6S/c1-7-8-15-42(39,40)34-30(37)28(20(2)3)33-29(36)26(35(6)31(38)25-17-21(4)16-22(5)18-25)19-23-9-11-24(12-10-23)27-13-14-32-41-27/h9-14,16-18,20,26,28H,7-8,15,19H2,1-6H3,(H,33,36)(H,34,37)/t26-,28+/m0/s1	IFLIQLQVUMXNFU-XTEPFMGCSA-N	50071446	CHEMBL72295::N-[(S)-1-[(R)-1-(Butane-1-sulfonylaminocarbonyl)-2-methyl-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 27000								ChEMBL	10.1016/s0960-894x(98)00388-6	10.7270/Q26M3609	9873522			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071446&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44312023	103965199		CHEMBL72295				ZINC26377223	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123407	CCCCS(=O)(=O)NC(=O)[C@H](NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)C	InChI=1S/C31H40N4O6S/c1-7-8-15-42(39,40)34-30(37)28(20(2)3)33-29(36)26(35(6)31(38)25-17-21(4)16-22(5)18-25)19-23-9-11-24(12-10-23)27-13-14-32-41-27/h9-14,16-18,20,26,28H,7-8,15,19H2,1-6H3,(H,33,36)(H,34,37)/t26-,28-/m1/s1	IFLIQLQVUMXNFU-IXCJQBJRSA-N	50071447	CHEMBL310919::N-[(R)-1-[(R)-1-(Butane-1-sulfonylaminocarbonyl)-2-methyl-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 850								ChEMBL	10.1016/s0960-894x(98)00388-6	10.7270/Q26M3609	9873522			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071447&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311810	103965200		CHEMBL310919				ZINC26379455	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123409	CCCCS(=O)(=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)C	InChI=1S/C31H40N4O6S/c1-7-8-15-42(39,40)34-30(37)28(20(2)3)33-29(36)26(35(6)31(38)25-17-21(4)16-22(5)18-25)19-23-9-11-24(12-10-23)27-13-14-32-41-27/h9-14,16-18,20,26,28H,7-8,15,19H2,1-6H3,(H,33,36)(H,34,37)/t26-,28-/m0/s1	IFLIQLQVUMXNFU-XCZPVHLTSA-N	50071448	CHEMBL307033::N-[(S)-1-[(S)-1-(Butane-1-sulfonylaminocarbonyl)-2-methyl-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 6800								ChEMBL	10.1016/s0960-894x(98)00388-6	10.7270/Q26M3609	9873522			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071448&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9830098	103965201		CHEMBL307033				ZINC14293979	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50123410	CCCCS(=O)(=O)NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccc(cc1)-c1ccno1)N(C)C(=O)c1cc(C)cc(C)c1)C(C)C	InChI=1S/C31H40N4O6S/c1-7-8-15-42(39,40)34-30(37)28(20(2)3)33-29(36)26(35(6)31(38)25-17-21(4)16-22(5)18-25)19-23-9-11-24(12-10-23)27-13-14-32-41-27/h9-14,16-18,20,26,28H,7-8,15,19H2,1-6H3,(H,33,36)(H,34,37)/t26-,28+/m1/s1	IFLIQLQVUMXNFU-IAPPQJPRSA-N	50071425	CHEMBL311854::N-[(R)-1-[(S)-1-(Butane-1-sulfonylaminocarbonyl)-2-methyl-propylcarbamoyl]-2-(4-isoxazol-5-yl-phenyl)-ethyl]-3,5,N-trimethyl-benzamide	Endothelin-1 receptor		 1.5								ChEMBL	10.1016/s0960-894x(98)00388-6	10.7270/Q26M3609	9873522			Sakaki, J; Murata, T; Yuumoto, Y; Nakamura, I; Hayakawa, K	Takarazuka Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071425&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9938533	103965178		CHEMBL311854				ZINC03942097	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139081	CCc1ccc(cc1)C(OCCc1ccc(OC)c(OC)c1)(C(Oc1nc(C)cc(OC)n1)C(O)=O)c1ccc(CC)cc1	InChI=1S/C35H40N2O7/c1-7-24-9-14-27(15-10-24)35(28-16-11-25(8-2)12-17-28,43-20-19-26-13-18-29(40-4)30(22-26)41-5)32(33(38)39)44-34-36-23(3)21-31(37-34)42-6/h9-18,21-22,32H,7-8,19-20H2,1-6H3,(H,38,39)	UTSWGARHIRATMS-UHFFFAOYSA-N	50079416	3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-3,3-bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-propionic acid::CHEMBL318535	Endothelin-1 receptor		 39.3								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079416&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10769887	103971668		CHEMBL318535				ZINC26818677	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139083	Cc1ccc(CCCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1	InChI=1S/C31H32N2O4/c1-22-16-18-25(19-17-22)11-10-20-36-31(26-12-6-4-7-13-26,27-14-8-5-9-15-27)28(29(34)35)37-30-32-23(2)21-24(3)33-30/h4-9,12-19,21,28H,10-11,20H2,1-3H3,(H,34,35)	OCZIRSIFHBBDKN-UHFFFAOYSA-N	50079421	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-(3-p-tolyl-propoxy)-propionic acid::CHEMBL103190	Endothelin-1 receptor		 23								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079421&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10505434	103971673		CHEMBL103190				ZINC13799578	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139084	Cc1ccc(\C=C\COC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1	InChI=1S/C31H30N2O4/c1-22-16-18-25(19-17-22)11-10-20-36-31(26-12-6-4-7-13-26,27-14-8-5-9-15-27)28(29(34)35)37-30-32-23(2)21-24(3)33-30/h4-19,21,28H,20H2,1-3H3,(H,34,35)/b11-10+	ZHXNJGISXVIIND-ZHACJKMWSA-N	50079419	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-((E)-3-p-tolyl-allyloxy)-propionic acid::CHEMBL321984	Endothelin-1 receptor		 32								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079419&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10505357	103971671		CHEMBL321984				ZINC13799584	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139085	COc1ccc(CCOC(C(Oc2nc3COCc3c(OC)n2)C(O)=O)(c2ccc(C)cc2)c2ccc(C)cc2)cc1	InChI=1S/C33H34N2O7/c1-21-5-11-24(12-6-21)33(25-13-7-22(2)8-14-25,41-18-17-23-9-15-26(38-3)16-10-23)29(31(36)37)42-32-34-28-20-40-19-27(28)30(35-32)39-4/h5-16,29H,17-20H2,1-4H3,(H,36,37)	TZPUDTSXRNOQNK-UHFFFAOYSA-N	50079420	2-(4-Methoxy-5,7-dihydro-furo[3,4-d]pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-di-p-tolyl-propionic acid::CHEMBL318146	Endothelin-1 receptor		 105								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079420&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333366	103971672		CHEMBL318146				ZINC26826220	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139087	COc1cc(\C=C\COC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc(OC)c1OC	InChI=1S/C33H34N2O7/c1-22-19-23(2)35-32(34-22)42-30(31(36)37)33(25-14-8-6-9-15-25,26-16-10-7-11-17-26)41-18-12-13-24-20-27(38-3)29(40-5)28(21-24)39-4/h6-17,19-21,30H,18H2,1-5H3,(H,36,37)/b13-12+	MSRYVIMFULZUGC-OUKQBFOZSA-N	50079422	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-[(E)-3-(3,4,5-trimethoxy-phenyl)-allyloxy]-propionic acid::CHEMBL275471	Endothelin-1 receptor		 48								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079422&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793160	103971674		CHEMBL275471				ZINC26821343	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139089	Cc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(O)cc2)(c2ccccc2)c2ccccc2)n1	InChI=1S/C29H28N2O5/c1-20-19-21(2)31-28(30-20)36-26(27(33)34)29(23-9-5-3-6-10-23,24-11-7-4-8-12-24)35-18-17-22-13-15-25(32)16-14-22/h3-16,19,26,32H,17-18H2,1-2H3,(H,33,34)	VWXMUZZYWKEWJY-UHFFFAOYSA-N	50079423	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-hydroxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid::CHEMBL102868	Endothelin-1 receptor		 3.48								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079423&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10528863	103971675		CHEMBL102868				ZINC13799609	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139090	COc1ccc(CCOC([C@H](Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1OC	InChI=1S/C31H32N2O6/c1-21-19-22(2)33-30(32-21)39-28(29(34)35)31(24-11-7-5-8-12-24,25-13-9-6-10-14-25)38-18-17-23-15-16-26(36-3)27(20-23)37-4/h5-16,19-20,28H,17-18H2,1-4H3,(H,34,35)/t28-/m1/s1	CLSJNXXMIVKULC-MUUNZHRXSA-N	50079424	(S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL316735	Endothelin-1 receptor		 2.15								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079424&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9893800	103971676		CHEMBL316735					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139092	COc1ccc(CCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1	InChI=1S/C30H30N2O5/c1-21-20-22(2)32-29(31-21)37-27(28(33)34)30(24-10-6-4-7-11-24,25-12-8-5-9-13-25)36-19-18-23-14-16-26(35-3)17-15-23/h4-17,20,27H,18-19H2,1-3H3,(H,33,34)	NPLNAUBFRRXHRY-UHFFFAOYSA-N	50079427	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid::CHEMBL101069	Endothelin-1 receptor		 6.03								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079427&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10648996	103971679		CHEMBL101069				ZINC13799599	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139093	COc1cc(CCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc(OC)c1OC	InChI=1S/C32H34N2O7/c1-21-18-22(2)34-31(33-21)41-29(30(35)36)32(24-12-8-6-9-13-24,25-14-10-7-11-15-25)40-17-16-23-19-26(37-3)28(39-5)27(20-23)38-4/h6-15,18-20,29H,16-17H2,1-5H3,(H,35,36)	WZCUCQGZYXGPHF-UHFFFAOYSA-N	50079426	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-[2-(3,4,5-trimethoxy-phenyl)-ethoxy]-propionic acid::CHEMBL103201	Endothelin-1 receptor		 1.38								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079426&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10840560	103971678		CHEMBL103201				ZINC26821875	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139094	COc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(OC)c(OC)c2)(c2ccccc2)c2ccccc2)n1	InChI=1S/C31H32N2O7/c1-21-19-27(38-4)33-30(32-21)40-28(29(34)35)31(23-11-7-5-8-12-23,24-13-9-6-10-14-24)39-18-17-22-15-16-25(36-2)26(20-22)37-3/h5-16,19-20,28H,17-18H2,1-4H3,(H,34,35)	OOUHAJURRQCGRG-UHFFFAOYSA-N	50079429	3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL319031	Endothelin-1 receptor		 2.37								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079429&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10768897	103971681		CHEMBL319031				ZINC26818223	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139095	Cc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(Cl)cc2)(c2ccccc2)c2ccccc2)n1	InChI=1S/C29H27ClN2O4/c1-20-19-21(2)32-28(31-20)36-26(27(33)34)29(23-9-5-3-6-10-23,24-11-7-4-8-12-24)35-18-17-22-13-15-25(30)16-14-22/h3-16,19,26H,17-18H2,1-2H3,(H,33,34)	PMUCOFCFESYTCH-UHFFFAOYSA-N	50079428	3-[2-(4-Chloro-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL418992	Endothelin-1 receptor		 19.8								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079428&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10673091	103971680		CHEMBL418992				ZINC13799603	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139096	COc1ccc(CCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1OC	InChI=1S/C31H32N2O6/c1-21-19-22(2)33-30(32-21)39-28(29(34)35)31(24-11-7-5-8-12-24,25-13-9-6-10-14-25)38-18-17-23-15-16-26(36-3)27(20-23)37-4/h5-16,19-20,28H,17-18H2,1-4H3,(H,34,35)	CLSJNXXMIVKULC-UHFFFAOYSA-N	50079417	3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL102405::Feloprentan	Endothelin-1 receptor		 3.49								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079417&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6433100	103971669		CHEMBL102405				ZINC01488193	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139097	COc1ccc(OC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1OC	InChI=1S/C29H28N2O6/c1-19-17-20(2)31-28(30-19)36-26(27(32)33)29(21-11-7-5-8-12-21,22-13-9-6-10-14-22)37-23-15-16-24(34-3)25(18-23)35-4/h5-18,26H,1-4H3,(H,32,33)	GHIWIAMAJCWXDD-UHFFFAOYSA-N	50079431	3-(3,4-Dimethoxy-phenoxy)-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL320224	Endothelin-1 receptor		 0.48								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079431&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10815239	103971683		CHEMBL320224				ZINC13799589	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139098	Cc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(cc2)C(O)=O)(c2ccccc2)c2ccccc2)n1	InChI=1S/C30H28N2O6/c1-20-19-21(2)32-29(31-20)38-26(28(35)36)30(24-9-5-3-6-10-24,25-11-7-4-8-12-25)37-18-17-22-13-15-23(16-14-22)27(33)34/h3-16,19,26H,17-18H2,1-2H3,(H,33,34)(H,35,36)	JNFNRBRGVCBLHK-UHFFFAOYSA-N	50079432	4-{2-[2-Carboxy-2-(4,6-dimethyl-pyrimidin-2-yloxy)-1,1-diphenyl-ethoxy]-ethyl}-benzoic acid::CHEMBL101742	Endothelin-1 receptor		 1.5								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079432&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10553793	103971684		CHEMBL101742				ZINC13799614	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139100	COc1cc(CCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)ccc1OCC(O)=O	InChI=1S/C32H32N2O8/c1-21-18-22(2)34-31(33-21)42-29(30(37)38)32(24-10-6-4-7-11-24,25-12-8-5-9-13-25)41-17-16-23-14-15-26(27(19-23)39-3)40-20-28(35)36/h4-15,18-19,29H,16-17,20H2,1-3H3,(H,35,36)(H,37,38)	JKISBSRHDYZOEO-UHFFFAOYSA-N	50079430	3-[2-(4-Carboxymethoxy-3-methoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL103695	Endothelin-1 receptor		 1.92								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079430&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10555112	103971682		CHEMBL103695				ZINC26819108	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139101	CCc1ccc(cc1)C(OCCc1ccc(OC)cc1)(C(Oc1nc(C)cc(OC)n1)C(O)=O)c1ccc(CC)cc1	InChI=1S/C34H38N2O6/c1-6-24-8-14-27(15-9-24)34(28-16-10-25(7-2)11-17-28,41-21-20-26-12-18-29(39-4)19-13-26)31(32(37)38)42-33-35-23(3)22-30(36-33)40-5/h8-19,22,31H,6-7,20-21H2,1-5H3,(H,37,38)	BWMGPBPXTCNARL-UHFFFAOYSA-N	50079433	3,3-Bis-(4-ethyl-phenyl)-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-propionic acid::CHEMBL322996	Endothelin-1 receptor		 155								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079433&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10603135	103971685		CHEMBL322996				ZINC26821552	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139109	Cc1ccc(CCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1	InChI=1S/C30H30N2O4/c1-21-14-16-24(17-15-21)18-19-35-30(25-10-6-4-7-11-25,26-12-8-5-9-13-26)27(28(33)34)36-29-31-22(2)20-23(3)32-29/h4-17,20,27H,18-19H2,1-3H3,(H,33,34)	VJGDGBUWSOZGFC-UHFFFAOYSA-N	50079436	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-3-(2-p-tolyl-ethoxy)-propionic acid::CHEMBL100954	Endothelin-1 receptor		 32.5								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079436&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10624645	103971688		CHEMBL100954				ZINC13799572	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139110	COc1ccc(CCOC(C(Oc2nc3CCCc3c(OC)n2)C(O)=O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1OC	InChI=1S/C33H32Cl2N2O7/c1-40-27-16-7-20(19-28(27)41-2)17-18-43-33(21-8-12-23(34)13-9-21,22-10-14-24(35)15-11-22)29(31(38)39)44-32-36-26-6-4-5-25(26)30(37-32)42-3/h7-16,19,29H,4-6,17-18H2,1-3H3,(H,38,39)	ZXXCWRYARSIMPM-UHFFFAOYSA-N	50079437	3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6,7-dihydro-5H-cyclopentapyrimidin-2-yloxy)-propionic acid::CHEMBL103605	Endothelin-1 receptor		 290								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079437&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10508342	103971689		CHEMBL103605				ZINC26818687	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139111	CCOc1ccc(CCOC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1OC	InChI=1S/C32H34N2O6/c1-5-38-27-17-16-24(21-28(27)37-4)18-19-39-32(25-12-8-6-9-13-25,26-14-10-7-11-15-26)29(30(35)36)40-31-33-22(2)20-23(3)34-31/h6-17,20-21,29H,5,18-19H2,1-4H3,(H,35,36)	WUNUEBZYLIUGHH-UHFFFAOYSA-N	50079435	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-[2-(4-ethoxy-3-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid::CHEMBL102797	Endothelin-1 receptor		 3.13								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11800649	103971687		CHEMBL102797				ZINC26824600	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139116	COc1ccc(COC(C(Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1OC	InChI=1S/C30H30N2O6/c1-20-17-21(2)32-29(31-20)38-27(28(33)34)30(23-11-7-5-8-12-23,24-13-9-6-10-14-24)37-19-22-15-16-25(35-3)26(18-22)36-4/h5-18,27H,19H2,1-4H3,(H,33,34)	SBPQWNOPLSRSMS-UHFFFAOYSA-N	50079438	3-(3,4-Dimethoxy-benzyloxy)-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL101587	Endothelin-1 receptor		 2								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079438&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11799973	103971690		CHEMBL101587				ZINC13799594	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139121	CCc1ccc(cc1)C(OCCc1ccc(OC)cc1)(C(Oc1nc(C)cc(C)n1)C(O)=O)c1ccc(CC)cc1	InChI=1S/C34H38N2O5/c1-6-25-8-14-28(15-9-25)34(29-16-10-26(7-2)11-17-29,40-21-20-27-12-18-30(39-5)19-13-27)31(32(37)38)41-33-35-23(3)22-24(4)36-33/h8-19,22,31H,6-7,20-21H2,1-5H3,(H,37,38)	VQUBCMKIGJZUME-UHFFFAOYSA-N	50079434	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3,3-bis-(4-ethyl-phenyl)-3-[2-(4-methoxy-phenyl)-ethoxy]-propionic acid::CHEMBL317716	Endothelin-1 receptor		 250								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079434&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10721484	103971686		CHEMBL317716				ZINC26818539	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139123	COc1cc(C)nc(OC(C(O)=O)C(OCCc2ccc(OC)c(OC)c2)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)n1	InChI=1S/C31H30Cl2N2O7/c1-19-17-27(40-4)35-30(34-19)42-28(29(36)37)31(21-6-10-23(32)11-7-21,22-8-12-24(33)13-9-22)41-16-15-20-5-14-25(38-2)26(18-20)39-3/h5-14,17-18,28H,15-16H2,1-4H3,(H,36,37)	RIFDNBGSPYSLKK-UHFFFAOYSA-N	50079418	3,3-Bis-(4-chloro-phenyl)-3-[2-(3,4-dimethoxy-phenyl)-ethoxy]-2-(4-methoxy-6-methyl-pyrimidin-2-yloxy)-propionic acid::CHEMBL276288	Endothelin-1 receptor		 230								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079418&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11801906	103971670		CHEMBL276288				ZINC26818697	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139125	COc1ccc(CCOC(C(Oc2nc(C)cc(OC)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1	InChI=1S/C30H30N2O6/c1-21-20-26(36-3)32-29(31-21)38-27(28(33)34)30(23-10-6-4-7-11-23,24-12-8-5-9-13-24)37-19-18-22-14-16-25(35-2)17-15-22/h4-17,20,27H,18-19H2,1-3H3,(H,33,34)	PYQNCKSTTLEMCS-UHFFFAOYSA-N	50079439	2-(4-Methoxy-6-methyl-pyrimidin-2-yloxy)-3-[2-(4-methoxy-phenyl)-ethoxy]-3,3-diphenyl-propionic acid::CHEMBL102307	Endothelin-1 receptor		 1.95								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079439&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11799974	103971691		CHEMBL102307				ZINC13799619	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50139127	Cc1cc(C)nc(OC(C(O)=O)C(OCCc2ccccc2)(c2ccccc2)c2ccccc2)n1	InChI=1S/C29H28N2O4/c1-21-20-22(2)31-28(30-21)35-26(27(32)33)29(24-14-8-4-9-15-24,25-16-10-5-11-17-25)34-19-18-23-12-6-3-7-13-23/h3-17,20,26H,18-19H2,1-2H3,(H,32,33)	QWDHLTWAAVZDIR-UHFFFAOYSA-N	50079425	2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-phenethyloxy-3,3-diphenyl-propionic acid::CHEMBL317233	Endothelin-1 receptor		 25								ChEMBL	10.1021/jm9910425	10.7270/Q2HD7TV6	10447946			Amberg, W; Hergenroder, S; Hillen, H; Jansen, R; Kettschau, G; Kling, A; Klinge, D; Raschack, M; Riechers, H; Unger, L	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079425&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3921421	103971677		CHEMBL317233				ZINC13140305	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136174	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCCN2CCN(C)CC2)c1)c1ccc2OCOc2c1	InChI=1S/C33H36N2O7/c1-34-14-16-35(17-15-34)13-4-18-39-27-6-3-5-23(19-27)20-28-31(24-7-12-29-30(21-24)41-22-40-29)32(36)42-33(28,37)25-8-10-26(38-2)11-9-25/h3,5-12,19,21,37H,4,13-18,20,22H2,1-2H3	NWLVAXXEZKFLHY-UHFFFAOYSA-N	50077928	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-{3-[3-(4-methyl-piperazin-1-yl)-propoxy]-benzyl}-5H-furan-2-one::CHEMBL71787	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077928&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10745668	103970616		CHEMBL71787				ZINC26284175	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136177	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCC(O)=O)c1)c1ccc2OCOc2c1	InChI=1S/C29H26O11/c1-34-19-7-5-18(6-8-19)29(33)20(26(28(32)40-29)17-4-9-21-22(13-17)39-15-38-21)10-16-11-23(35-2)27(36-3)24(12-16)37-14-25(30)31/h4-9,11-13,33H,10,14-15H2,1-3H3,(H,30,31)	GUYZWSHWBLUIHH-UHFFFAOYSA-N	50077931	CHEMBL70017::{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-acetic acid	Endothelin-1 receptor			 8.5							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077931&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10840410	103970619		CHEMBL70017				ZINC26272881	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136181	COC(=O)COc1cc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc(OC)c1OC	InChI=1S/C30H28O11/c1-34-20-8-6-19(7-9-20)30(33)21(27(29(32)41-30)18-5-10-22-23(14-18)40-16-39-22)11-17-12-24(35-2)28(37-4)25(13-17)38-15-26(31)36-3/h5-10,12-14,33H,11,15-16H2,1-4H3	IECXSVOMLVKXGN-UHFFFAOYSA-N	50077935	CHEMBL308646::{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-acetic acid methyl ester	Endothelin-1 receptor			 0.2							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077935&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10578853	103970623		CHEMBL308646				ZINC26277829	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136184	COC(=O)CCCCOc1cc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc(OC)c1OC	InChI=1S/C33H34O11/c1-37-23-11-9-22(10-12-23)33(36)24(30(32(35)44-33)21-8-13-25-26(18-21)43-19-42-25)15-20-16-27(38-2)31(40-4)28(17-20)41-14-6-5-7-29(34)39-3/h8-13,16-18,36H,5-7,14-15,19H2,1-4H3	FIMDOJGUQJFHTD-UHFFFAOYSA-N	50077930	5-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-pentanoic acid methyl ester::CHEMBL291058	Endothelin-1 receptor			 0.05							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077930&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10722385	103970618		CHEMBL291058				ZINC26275653	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136185	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor			 0.3							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136187	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCN2CCOCC2)c1)c1ccc2OCOc2c1	InChI=1S/C33H35NO10/c1-37-24-7-5-23(6-8-24)33(36)25(30(32(35)44-33)22-4-9-26-27(19-22)43-20-42-26)16-21-17-28(38-2)31(39-3)29(18-21)41-15-12-34-10-13-40-14-11-34/h4-9,17-19,36H,10-16,20H2,1-3H3	KBZGUXPZOIBUME-UHFFFAOYSA-N	50077934	3-Benzo[1,3]dioxol-5-yl-4-[3,4-dimethoxy-5-(2-morpholin-4-yl-ethoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL302974	Endothelin-1 receptor			 0.2							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077934&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10722371	103970622		CHEMBL302974				ZINC26264896	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136191	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCC(O)=O)c1)c1ccc2OCOc2c1	InChI=1S/C31H30O11/c1-36-21-9-7-20(8-10-21)31(35)22(28(30(34)42-31)19-6-11-23-24(16-19)41-17-40-23)13-18-14-25(37-2)29(38-3)26(15-18)39-12-4-5-27(32)33/h6-11,14-16,35H,4-5,12-13,17H2,1-3H3,(H,32,33)	YOUSJXJDRAULJM-UHFFFAOYSA-N	50077936	4-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-butyric acid::CHEMBL304762	Endothelin-1 receptor			 0.29							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077936&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10769526	103970624		CHEMBL304762				ZINC26268024	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136192	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCN(C)C)c1)c1ccc2OCOc2c1	InChI=1S/C32H35NO9/c1-33(2)13-6-14-39-28-17-20(16-27(37-4)30(28)38-5)15-24-29(21-7-12-25-26(18-21)41-19-40-25)31(34)42-32(24,35)22-8-10-23(36-3)11-9-22/h7-12,16-18,35H,6,13-15,19H2,1-5H3	CQVCPSUMZXOSTH-UHFFFAOYSA-N	50077943	3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-propoxy)-4,5-dimethoxy-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL68269	Endothelin-1 receptor			 1							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077943&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10555191	103970631		CHEMBL68269				ZINC26280171	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136193	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCS([O-])(=O)=O)c1)c1ccc2OCOc2c1	InChI=1S/C30H30O12S/c1-36-21-8-6-20(7-9-21)30(32)22(27(29(31)42-30)19-5-10-23-24(16-19)41-17-40-23)13-18-14-25(37-2)28(38-3)26(15-18)39-11-4-12-43(33,34)35/h5-10,14-16,32H,4,11-13,17H2,1-3H3,(H,33,34,35)/p-1	GNKXKTKCZOIGSL-UHFFFAOYSA-M	50077944	CHEMBL408055::Sodium; 3-{5-[4-benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-propane-1-sulfonate	Endothelin-1 receptor			 0.38							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077944&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931108	103970632		CHEMBL408055			C15521	ZINC05493658	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136194	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCN2CCOCC2)c1)c1ccc2OCOc2c1	InChI=1S/C31H31NO8/c1-35-24-8-6-23(7-9-24)31(34)26(29(30(33)40-31)22-5-10-27-28(19-22)39-20-38-27)18-21-3-2-4-25(17-21)37-16-13-32-11-14-36-15-12-32/h2-10,17,19,34H,11-16,18,20H2,1H3	TUJJSLRNRRQPKT-UHFFFAOYSA-N	50077942	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-[3-(2-morpholin-4-yl-ethoxy)-benzyl]-5H-furan-2-one::CHEMBL305267	Endothelin-1 receptor			 4							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077942&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10650210	103970630		CHEMBL305267				ZINC26273588	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136195	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCN(C)C)c1)c1ccc2OCOc2c1	InChI=1S/C31H33NO9/c1-32(2)12-13-38-27-16-19(15-26(36-4)29(27)37-5)14-23-28(20-6-11-24-25(17-20)40-18-39-24)30(33)41-31(23,34)21-7-9-22(35-3)10-8-21/h6-11,15-17,34H,12-14,18H2,1-5H3	QAYBUBGSILAAPP-UHFFFAOYSA-N	50077945	3-Benzo[1,3]dioxol-5-yl-4-[3-(2-dimethylamino-ethoxy)-4,5-dimethoxy-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL307330	Endothelin-1 receptor			 2.8							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077945&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9810190	103970633		CHEMBL307330				ZINC26270844	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136198	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCCN(C)C)c1)c1ccc2OCOc2c1	InChI=1S/C30H31NO7/c1-31(2)14-5-15-35-24-7-4-6-20(16-24)17-25-28(21-8-13-26-27(18-21)37-19-36-26)29(32)38-30(25,33)22-9-11-23(34-3)12-10-22/h4,6-13,16,18,33H,5,14-15,17,19H2,1-3H3	XGNOQSFKTHSFOC-UHFFFAOYSA-N	50077940	3-Benzo[1,3]dioxol-5-yl-4-[3-(3-dimethylamino-propoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL66762	Endothelin-1 receptor			 28							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077940	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077940&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10839618	103970628		CHEMBL66762				ZINC13798170	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136201	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCCC(O)=O)c1)c1ccc2OCOc2c1	InChI=1S/C32H32O11/c1-37-22-10-8-21(9-11-22)32(36)23(29(31(35)43-32)20-7-12-24-25(17-20)42-18-41-24)14-19-15-26(38-2)30(39-3)27(16-19)40-13-5-4-6-28(33)34/h7-12,15-17,36H,4-6,13-14,18H2,1-3H3,(H,33,34)	PHPQCIBIIVOPOY-UHFFFAOYSA-N	50077946	5-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-pentanoic acid::CHEMBL69832	Endothelin-1 receptor			 0.3							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077946&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10555424	103970634		CHEMBL69832				ZINC26270094	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136202	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCN2CCCC2)c1)c1ccc2OCOc2c1	InChI=1S/C31H31NO7/c1-35-24-10-8-23(9-11-24)31(34)26(29(30(33)39-31)22-7-12-27-28(19-22)38-20-37-27)18-21-5-4-6-25(17-21)36-16-15-32-13-2-3-14-32/h4-12,17,19,34H,2-3,13-16,18,20H2,1H3	BCGHSMJUTFDZQE-UHFFFAOYSA-N	50077937	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-[3-(2-pyrrolidin-1-yl-ethoxy)-benzyl]-5H-furan-2-one::CHEMBL65939	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077937&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10673756	103970625		CHEMBL65939				ZINC13798177	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136203	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1ccc(OCCCN(C)C)cc1)c1ccc2OCOc2c1	InChI=1S/C30H31NO7/c1-31(2)15-4-16-35-24-10-5-20(6-11-24)17-25-28(21-7-14-26-27(18-21)37-19-36-26)29(32)38-30(25,33)22-8-12-23(34-3)13-9-22/h5-14,18,33H,4,15-17,19H2,1-3H3	QQXHFAXELLQPPS-UHFFFAOYSA-N	50077927	3-Benzo[1,3]dioxol-5-yl-4-[4-(3-dimethylamino-propoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL305035	Endothelin-1 receptor			>25000							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077927&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10506068	103970615		CHEMBL305035				ZINC13798184	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136204	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OCCN2CCOCC2)cc(OCCN2CCOCC2)c1)c1ccc2OCOc2c1	InChI=1S/C37H42N2O10/c1-42-29-5-3-28(4-6-29)37(41)32(35(36(40)49-37)27-2-7-33-34(23-27)48-25-47-33)22-26-20-30(45-18-12-38-8-14-43-15-9-38)24-31(21-26)46-19-13-39-10-16-44-17-11-39/h2-7,20-21,23-24,41H,8-19,22,25H2,1H3	XAJHFOTXBBAOCU-UHFFFAOYSA-N	50077939	3-Benzo[1,3]dioxol-5-yl-4-[3,5-bis-(2-morpholin-4-yl-ethoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL69353	Endothelin-1 receptor			>10							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077939&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10818246	103970627		CHEMBL69353				ZINC26277841	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136207	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCN2CCOCC2)c1)c1ccc2OCOc2c1	InChI=1S/C34H37NO10/c1-38-25-8-6-24(7-9-25)34(37)26(31(33(36)45-34)23-5-10-27-28(20-23)44-21-43-27)17-22-18-29(39-2)32(40-3)30(19-22)42-14-4-11-35-12-15-41-16-13-35/h5-10,18-20,37H,4,11-17,21H2,1-3H3	INTTYORIUAYXMN-UHFFFAOYSA-N	50077941	3-Benzo[1,3]dioxol-5-yl-4-[3,4-dimethoxy-5-(3-morpholin-4-yl-propoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL303484	Endothelin-1 receptor			 0.7							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077941&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10746431	103970629		CHEMBL303484				ZINC26274392	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136208	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCCN2CCOCC2)c1)c1ccc2OCOc2c1	InChI=1S/C32H33NO8/c1-36-25-9-7-24(8-10-25)32(35)27(30(31(34)41-32)23-6-11-28-29(20-23)40-21-39-28)19-22-4-2-5-26(18-22)38-15-3-12-33-13-16-37-17-14-33/h2,4-11,18,20,35H,3,12-17,19,21H2,1H3	OEMNPEMEFUYQJO-UHFFFAOYSA-N	50077947	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-[3-(3-morpholin-4-yl-propoxy)-benzyl]-5H-furan-2-one::CHEMBL302493	Endothelin-1 receptor			 2							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077947&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10816682	103970635		CHEMBL302493				ZINC26284189	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136209	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OCCN2CCOCC2)c(OC)c(OCCN2CCOCC2)c1)c1ccc2OCOc2c1	InChI=1S/C38H44N2O11/c1-43-29-6-4-28(5-7-29)38(42)30(35(37(41)51-38)27-3-8-31-32(24-27)50-25-49-31)21-26-22-33(47-19-13-39-9-15-45-16-10-39)36(44-2)34(23-26)48-20-14-40-11-17-46-18-12-40/h3-8,22-24,42H,9-21,25H2,1-2H3	OYYTVRHUXDYSDJ-UHFFFAOYSA-N	50077932	3-Benzo[1,3]dioxol-5-yl-5-hydroxy-4-[4-methoxy-3,5-bis-(2-morpholin-4-yl-ethoxy)-benzyl]-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL303712	Endothelin-1 receptor			 2000							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077932&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10604797	103970620		CHEMBL303712				ZINC26274379	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136210	COC(=O)CCCOc1cc(CC2=C(C(=O)OC2(O)c2ccc(OC)cc2)c2ccc3OCOc3c2)cc(OC)c1OC	InChI=1S/C32H32O11/c1-36-22-10-8-21(9-11-22)32(35)23(29(31(34)43-32)20-7-12-24-25(17-20)42-18-41-24)14-19-15-26(37-2)30(39-4)27(16-19)40-13-5-6-28(33)38-3/h7-12,15-17,35H,5-6,13-14,18H2,1-4H3	KNCYVPWSDRUANJ-UHFFFAOYSA-N	50077933	4-{5-[4-Benzo[1,3]dioxol-5-yl-2-hydroxy-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-3-ylmethyl]-2,3-dimethoxy-phenoxy}-butyric acid methyl ester::CHEMBL69986	Endothelin-1 receptor			 0.09							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077933&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10627272	103970621		CHEMBL69986				ZINC26272868	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136215	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OCCCN2CCN(C)CC2)c1)c1ccc2OCOc2c1	InChI=1S/C35H40N2O9/c1-36-13-15-37(16-14-36)12-5-17-43-31-20-23(19-30(41-3)33(31)42-4)18-27-32(24-6-11-28-29(21-24)45-22-44-28)34(38)46-35(27,39)25-7-9-26(40-2)10-8-25/h6-11,19-21,39H,5,12-18,22H2,1-4H3	RCWLWRDNZZXMJM-UHFFFAOYSA-N	50077938	3-Benzo[1,3]dioxol-5-yl-4-{3,4-dimethoxy-5-[3-(4-methyl-piperazin-1-yl)-propoxy]-benzyl}-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL304802	Endothelin-1 receptor			 2							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077938&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10579885	103970626		CHEMBL304802				ZINC26271144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50136216	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cccc(OCCN(C)C)c1)c1ccc2OCOc2c1	InChI=1S/C29H29NO7/c1-30(2)13-14-34-23-6-4-5-19(15-23)16-24-27(20-7-12-25-26(17-20)36-18-35-25)28(31)37-29(24,32)21-8-10-22(33-3)11-9-21/h4-12,15,17,32H,13-14,16,18H2,1-3H3	UVKFXUSMAGFAHF-UHFFFAOYSA-N	50077929	3-Benzo[1,3]dioxol-5-yl-4-[3-(2-dimethylamino-ethoxy)-benzyl]-5-hydroxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL305777	Endothelin-1 receptor			 27							ChEMBL	10.1021/jm980504w	10.7270/Q2V12404	10377221			Patt, WC; Cheng, XM; Repine, JT; Lee, C; Reisdorph, BR; Massa, MA; Doherty, AM; Welch, KM; Bryant, JW; Flynn, MA; Walker, DM; Schroeder, RL; Haleen, SJ; Keiser, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077929&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10744085	103970617		CHEMBL305777				ZINC13798163	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141142	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1ccc(C)cc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-17-4-10-23(18(2)12-17)30-26(32)15-31-14-22(20-7-11-24-25(13-20)37-16-36-24)27(29(33)34)28(31)19-5-8-21(35-3)9-6-19/h4-13,22,27-28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t22-,27-,28+/m1/s1	PUEQTWGTNQUURY-OFEZKSIWSA-N	50080586	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,4-dimethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL120106	Endothelin-1 receptor			 25							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080586&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10625269	103980729		CHEMBL120106				ZINC13800403	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141144	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m1/s1	MOTJMGVDPWRKOC-QPVYNBJUSA-N	50051007	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::A-127722::CHEMBL9194	Endothelin-1 receptor			 0.08							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			159594	103948098		CHEMBL9194				ZINC03812144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141146	CCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(CC)cccc1CC)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C32H36N2O6/c1-4-20-8-7-9-21(5-2)30(20)33-28(35)18-34-17-25(23-12-15-26-27(16-23)40-19-39-26)29(32(36)37)31(34)22-10-13-24(14-11-22)38-6-3/h7-16,25,29,31H,4-6,17-19H2,1-3H3,(H,33,35)(H,36,37)/t25-,29-,31+/m1/s1	RNNCMVHNZGHSLY-ICTSCBFQSA-N	50080588	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-ethoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL435385	Endothelin-1 receptor			 340							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080588&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10792636	103980731		CHEMBL435385				ZINC03953114	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141147	CCc1cc(F)cc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C31H33FN2O6/c1-4-18-12-22(32)13-19(5-2)29(18)33-27(35)16-34-15-24(21-8-11-25-26(14-21)40-17-39-25)28(31(36)37)30(34)20-6-9-23(38-3)10-7-20/h6-14,24,28,30H,4-5,15-17H2,1-3H3,(H,33,35)(H,36,37)/t24-,28-,30+/m1/s1	GAICYMPBDZVZOU-MLWJCNIFSA-N	50080589	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-4-fluoro-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL333972	Endothelin-1 receptor			 22							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080589&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10792711	103980732		CHEMBL333972				ZINC27187379	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141149	CCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C31H34N2O6/c1-4-19-7-6-8-20(5-2)29(19)32-27(34)17-33-16-24(22-11-14-25-26(15-22)39-18-38-25)28(31(35)36)30(33)21-9-12-23(37-3)13-10-21/h6-15,24,28,30H,4-5,16-18H2,1-3H3,(H,32,34)(H,35,36)/t24-,28-,30+/m1/s1	JMWQBPRIANCZRQ-MLWJCNIFSA-N	50080592	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL339657	Endothelin-1 receptor			 45							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080592&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10839947	103980735		CHEMBL339657				ZINC03953116	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141150	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(cccc1C(C)C)C(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C33H38N2O6/c1-19(2)24-7-6-8-25(20(3)4)31(24)34-29(36)17-35-16-26(22-11-14-27-28(15-22)41-18-40-27)30(33(37)38)32(35)21-9-12-23(39-5)13-10-21/h6-15,19-20,26,30,32H,16-18H2,1-5H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	IJWIKFGUGIKEKW-FUKIBTTHSA-N	50080591	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diisopropyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332627	Endothelin-1 receptor			 920							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080591&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10745418	103980734		CHEMBL332627				ZINC27194342	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141152	CCc1cccc(C)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H32N2O6/c1-4-19-7-5-6-18(2)28(19)31-26(33)16-32-15-23(21-10-13-24-25(14-21)38-17-37-24)27(30(34)35)29(32)20-8-11-22(36-3)12-9-20/h5-14,23,27,29H,4,15-17H2,1-3H3,(H,31,33)(H,34,35)/t23-,27-,29+/m1/s1	JPBZOZDHBRRLBM-LFOKJVLGSA-N	50080594	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2-ethyl-6-methyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL421073	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080594&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10529868	103980737		CHEMBL421073				ZINC27192987	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141154	CCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OCCOC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C33H38N2O7/c1-4-21-7-6-8-22(5-2)31(21)34-29(36)19-35-18-26(24-11-14-27-28(17-24)42-20-41-27)30(33(37)38)32(35)23-9-12-25(13-10-23)40-16-15-39-3/h6-14,17,26,30,32H,4-5,15-16,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	YPCZZHQNKFJAOP-FUKIBTTHSA-N	50080597	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-[4-(2-methoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid::CHEMBL331625	Endothelin-1 receptor			 4200							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080597&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10816963	103980740		CHEMBL331625				ZINC27189561	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141155	CCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(CCOC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C33H38N2O6/c1-4-22-7-6-8-23(5-2)31(22)34-29(36)19-35-18-26(25-13-14-27-28(17-25)41-20-40-27)30(33(37)38)32(35)24-11-9-21(10-12-24)15-16-39-3/h6-14,17,26,30,32H,4-5,15-16,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	FGUXLHMMTIYRQF-FUKIBTTHSA-N	50080596	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-[4-(2-methoxy-ethyl)-phenyl]-pyrrolidine-3-carboxylic acid::CHEMBL331066	Endothelin-1 receptor			 11000							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080596&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10769177	103980739		CHEMBL331066				ZINC27196293	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141156	CCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(CC)cccc1CC)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C32H36N2O6/c1-4-20-8-7-9-21(5-2)30(20)33-28(35)18-34-17-25(23-12-15-26-27(16-23)40-19-39-26)29(32(36)37)31(34)22-10-13-24(14-11-22)38-6-3/h7-16,25,29,31H,4-6,17-19H2,1-3H3,(H,33,35)(H,36,37)/t25-,29-,31+/m1/s1	RNNCMVHNZGHSLY-ICTSCBFQSA-N	50080588	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-ethoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL435385	Endothelin-1 receptor			 340							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080588&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10792636	103980731		CHEMBL435385				ZINC03953114	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141157	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1ccc(C)c(C)c1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-17-4-8-21(12-18(17)2)30-26(32)15-31-14-23(20-7-11-24-25(13-20)37-16-36-24)27(29(33)34)28(31)19-5-9-22(35-3)10-6-19/h4-13,23,27-28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t23-,27-,28+/m1/s1	ZHWQNJCSTDEVGM-QPVYNBJUSA-N	50080598	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(3,4-dimethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332431	Endothelin-1 receptor			 50							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080598&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11799625	103980741		CHEMBL332431				ZINC13800411	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141158	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(C)cccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-17-5-4-6-18(2)27(17)30-25(32)15-31-14-22(20-9-12-23-24(13-20)37-16-36-23)26(29(33)34)28(31)19-7-10-21(35-3)11-8-19/h4-13,22,26,28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t22-,26-,28+/m1/s1	OSRCBCUYZBTKBZ-QIDLSXJSSA-N	50080599	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-dimethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL331767	Endothelin-1 receptor			 33							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080599&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10625270	103980742		CHEMBL331767				ZINC13800408	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141160	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(OC)cccc1OC)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O8/c1-35-19-10-7-17(8-11-19)28-26(29(33)34)20(18-9-12-21-24(13-18)39-16-38-21)14-31(28)15-25(32)30-27-22(36-2)5-4-6-23(27)37-3/h4-13,20,26,28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t20-,26-,28+/m1/s1	BKGYGEADRLJUHK-LVPRMVSMSA-N	50080600	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-dimethoxy-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL122832	Endothelin-1 receptor			 16							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080600&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10816152	103980743		CHEMBL122832				ZINC27197878	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141161	CCc1cc(CC)c(NC(=O)CN2C[C@@H]([C@H]([C@@H]2c2ccc(OC)cc2)C(O)=O)c2ccc3OCOc3c2)c(CC)c1	InChI=1S/C33H38N2O6/c1-5-20-14-21(6-2)31(22(7-3)15-20)34-29(36)18-35-17-26(24-10-13-27-28(16-24)41-19-40-27)30(33(37)38)32(35)23-8-11-25(39-4)12-9-23/h8-16,26,30,32H,5-7,17-19H2,1-4H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	BYIKTFONIZDLEI-FUKIBTTHSA-N	50080602	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(2,4,6-triethyl-phenylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid::CHEMBL420729	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080602&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10792934	103980745		CHEMBL420729				ZINC27190258	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141164	CCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(CC)cccc1CC)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C33H38N2O6/c1-4-16-39-25-13-10-23(11-14-25)32-30(33(37)38)26(24-12-15-27-28(17-24)41-20-40-27)18-35(32)19-29(36)34-31-21(5-2)8-7-9-22(31)6-3/h7-15,17,26,30,32H,4-6,16,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	LQEHCKYYIXQEBM-FUKIBTTHSA-N	50080601	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-propoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332794	Endothelin-1 receptor			 9900							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080601&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5310991	103980744		CHEMBL332794		1009		ZINC03953115	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141165	CCCCCS(=O)(=O)N(CCC)CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)c(F)c1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H39FN2O7S/c1-4-6-7-15-40(35,36)32(12-5-2)14-13-31-18-22(20-8-11-25-26(17-20)39-19-38-25)27(29(33)34)28(31)21-9-10-24(37-3)23(30)16-21/h8-11,16-17,22,27-28H,4-7,12-15,18-19H2,1-3H3,(H,33,34)/t22-,27-,28+/m1/s1	JVWVTPZZEHLARL-OFEZKSIWSA-N	50061074	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(3-fluoro-4-methoxy-phenyl)-1-{2-[(pentane-1-sulfonyl)-propyl-amino]-ethyl}-pyrrolidine-3-carboxylic acid::A-182086::CHEMBL111277	Endothelin-1 receptor			 0.08							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061074&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9916235	103956661		CHEMBL111277				ZINC03936863	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141166	CCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(CC)cccc1CC)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C33H38N2O6/c1-4-16-39-25-13-10-23(11-14-25)32-30(33(37)38)26(24-12-15-27-28(17-24)41-20-40-27)18-35(32)19-29(36)34-31-21(5-2)8-7-9-22(31)6-3/h7-15,17,26,30,32H,4-6,16,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	LQEHCKYYIXQEBM-FUKIBTTHSA-N	50080601	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-propoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332794	Endothelin-1 receptor			 9900							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080601&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5310991	103980744		CHEMBL332794		1009		ZINC03953115	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141168	CCCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C32H36N2O6/c1-4-7-21-9-6-8-20(5-2)30(21)33-28(35)18-34-17-25(23-12-15-26-27(16-23)40-19-39-26)29(32(36)37)31(34)22-10-13-24(38-3)14-11-22/h6,8-16,25,29,31H,4-5,7,17-19H2,1-3H3,(H,33,35)(H,36,37)/t25-,29-,31+/m1/s1	APXDEEHRWJDGMC-ICTSCBFQSA-N	50080585	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2-ethyl-6-propyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL123997	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080585&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10602620	103980728		CHEMBL123997				ZINC27194353	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141171	CCc1cccc(CC)c1N(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C32H36N2O6/c1-5-20-8-7-9-21(6-2)30(20)33(3)28(35)18-34-17-25(23-12-15-26-27(16-23)40-19-39-26)29(32(36)37)31(34)22-10-13-24(38-4)14-11-22/h7-16,25,29,31H,5-6,17-19H2,1-4H3,(H,36,37)/t25-,29-,31+/m1/s1	ZDGQZBNPWPRKMF-ICTSCBFQSA-N	50080608	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{[(2,6-diethyl-phenyl)-methyl-carbamoyl]-methyl}-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332093	Endothelin-1 receptor			 190							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080608&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10674095	103980751		CHEMBL332093				ZINC27195046	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141172	CCc1cc(C)cc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C32H36N2O6/c1-5-20-13-19(3)14-21(6-2)30(20)33-28(35)17-34-16-25(23-9-12-26-27(15-23)40-18-39-26)29(32(36)37)31(34)22-7-10-24(38-4)11-8-22/h7-15,25,29,31H,5-6,16-18H2,1-4H3,(H,33,35)(H,36,37)/t25-,29-,31+/m1/s1	KEZZZBNAPVGBEW-ICTSCBFQSA-N	50080593	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-4-methyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL120962	Endothelin-1 receptor			 18							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080593&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10530585	103980736		CHEMBL120962				ZINC27190437	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141177	CCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC(C)C)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C33H38N2O6/c1-5-21-8-7-9-22(6-2)31(21)34-29(36)18-35-17-26(24-12-15-27-28(16-24)40-19-39-27)30(33(37)38)32(35)23-10-13-25(14-11-23)41-20(3)4/h7-16,20,26,30,32H,5-6,17-19H2,1-4H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	LZIKFQTYKMMZSV-FUKIBTTHSA-N	50080606	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-isopropoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL333009	Endothelin-1 receptor			 1500							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080606&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10650477	103980749		CHEMBL333009				ZINC27191420	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141178	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1cc(C)cc(C)c1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-17-10-18(2)12-21(11-17)30-26(32)15-31-14-23(20-6-9-24-25(13-20)37-16-36-24)27(29(33)34)28(31)19-4-7-22(35-3)8-5-19/h4-13,23,27-28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t23-,27-,28+/m1/s1	LQXOOIIURWJKRN-QPVYNBJUSA-N	50080603	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(3,5-dimethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL123077	Endothelin-1 receptor			 160							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080603&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10767778	103980746		CHEMBL123077				ZINC13800414	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141182	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1cccc(C)c1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-17-5-4-6-23(18(17)2)30-26(32)15-31-14-22(20-9-12-24-25(13-20)37-16-36-24)27(29(33)34)28(31)19-7-10-21(35-3)11-8-19/h4-13,22,27-28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t22-,27-,28+/m1/s1	UHXUKJPNFOYGKB-OFEZKSIWSA-N	50080604	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,3-dimethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332231	Endothelin-1 receptor			 16							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080604&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10744040	103980747		CHEMBL332231				ZINC13800400	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141184	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(C)cccc1C(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C31H34N2O6/c1-18(2)23-7-5-6-19(3)29(23)32-27(34)16-33-15-24(21-10-13-25-26(14-21)39-17-38-25)28(31(35)36)30(33)20-8-11-22(37-4)12-9-20/h5-14,18,24,28,30H,15-17H2,1-4H3,(H,32,34)(H,35,36)/t24-,28-,30+/m1/s1	FFXSFOBUYYTLRH-MLWJCNIFSA-N	50080587	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2-isopropyl-6-methyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL435185	Endothelin-1 receptor			 100							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080587&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10792316	103980730		CHEMBL435185				ZINC27201782	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141187	CCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OCCOC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C33H38N2O7/c1-4-21-7-6-8-22(5-2)31(21)34-29(36)19-35-18-26(24-11-14-27-28(17-24)42-20-41-27)30(33(37)38)32(35)23-9-12-25(13-10-23)40-16-15-39-3/h6-14,17,26,30,32H,4-5,15-16,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	YPCZZHQNKFJAOP-FUKIBTTHSA-N	50080597	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-[4-(2-methoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid::CHEMBL331625	Endothelin-1 receptor			 4200							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080597&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10816963	103980740		CHEMBL331625				ZINC27189561	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141190	CCc1cccc(OC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H32N2O7/c1-4-18-6-5-7-24(37-3)28(18)31-26(33)16-32-15-22(20-10-13-23-25(14-20)39-17-38-23)27(30(34)35)29(32)19-8-11-21(36-2)12-9-19/h5-14,22,27,29H,4,15-17H2,1-3H3,(H,31,33)(H,34,35)/t22-,27-,29+/m1/s1	HPSVGPXJVPTNPI-XRHWURSXSA-N	50080605	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2-ethyl-6-methoxy-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL332387	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080605&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10506430	103980748		CHEMBL332387				ZINC27195129	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141191	CCc1cc(cc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C32H34N2O8/c1-4-18-12-22(31(36)37)13-19(5-2)29(18)33-27(35)16-34-15-24(21-8-11-25-26(14-21)42-17-41-25)28(32(38)39)30(34)20-6-9-23(40-3)10-7-20/h6-14,24,28,30H,4-5,15-17H2,1-3H3,(H,33,35)(H,36,37)(H,38,39)/t24-,28-,30+/m1/s1	SRYQEUIBRIIYSG-MLWJCNIFSA-N	50080590	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(4-carboxy-2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL331758	Endothelin-1 receptor			 840							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080590&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10674642	103980733		CHEMBL331758				ZINC27186510	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141193	CCc1cccc(CC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C31H34N2O6/c1-4-19-7-6-8-20(5-2)29(19)32-27(34)17-33-16-24(22-11-14-25-26(15-22)39-18-38-25)28(31(35)36)30(33)21-9-12-23(37-3)13-10-21/h6-15,24,28,30H,4-5,16-18H2,1-3H3,(H,32,34)(H,35,36)/t24-,28-,30+/m1/s1	JMWQBPRIANCZRQ-MLWJCNIFSA-N	50080592	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-diethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL339657	Endothelin-1 receptor			 45.0							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080592&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10839947	103980735		CHEMBL339657				ZINC03953116	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141194	CCCc1cccc(CCC)c1NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C33H38N2O6/c1-4-7-21-9-6-10-22(8-5-2)31(21)34-29(36)19-35-18-26(24-13-16-27-28(17-24)41-20-40-27)30(33(37)38)32(35)23-11-14-25(39-3)15-12-23/h6,9-17,26,30,32H,4-5,7-8,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,32+/m1/s1	UJPMGYUNKDMJEA-FUKIBTTHSA-N	50080595	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-dipropyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL123305	Endothelin-1 receptor			 12							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080595&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10626646	103980738		CHEMBL123305				ZINC27194349	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141198	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1c(Br)cccc1Br)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C27H24Br2N2O6/c1-35-17-8-5-15(6-9-17)26-24(27(33)34)18(16-7-10-21-22(11-16)37-14-36-21)12-31(26)13-23(32)30-25-19(28)3-2-4-20(25)29/h2-11,18,24,26H,12-14H2,1H3,(H,30,32)(H,33,34)/t18-,24-,26+/m1/s1	KEGRAIQJSRYPGR-UFKXBGGNSA-N	50080609	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,6-dibromo-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL123926	Endothelin-1 receptor			 61							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080609&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10627805	103980752		CHEMBL123926				ZINC27195413	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141201	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)Nc1cc(C)ccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-17-4-5-18(2)23(12-17)30-26(32)15-31-14-22(20-8-11-24-25(13-20)37-16-36-24)27(29(33)34)28(31)19-6-9-21(35-3)10-7-19/h4-13,22,27-28H,14-16H2,1-3H3,(H,30,32)(H,33,34)/t22-,27-,28+/m1/s1	KNUFDNSKLOOTIB-OFEZKSIWSA-N	50080607	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,5-dimethyl-phenylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL122111	Endothelin-1 receptor			 33							ChEMBL	10.1021/jm990170q	10.7270/Q24T6HK7	10479298			von Geldern, TW; Tasker, AS; Sorensen, BK; Winn, M; Szczepankiewicz, BG; Dixon, DB; Chiou, WJ; Wang, L; Wessale, JL; Adler, A; Marsh, KC; Nguyen, B; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080607&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10577388	103980750		CHEMBL122111				ZINC13800406	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141202	CCC(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C30H32N2O6/c1-3-24(19-7-5-4-6-8-19)31-27(33)17-32-16-23(21-11-14-25-26(15-21)38-18-37-25)28(30(34)35)29(32)20-9-12-22(36-2)13-10-20/h4-15,23-24,28-29H,3,16-18H2,1-2H3,(H,31,33)(H,34,35)/t23-,24?,28-,29+/m1/s1	ZWURMMRAUYXFRY-OSLZXTCLSA-N	50080610	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(1-phenyl-propylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123107	Endothelin-1 receptor			 1							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080610&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10625694	103980753		CHEMBL123107				ZINC27196454	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141203	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(C)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H30N2O6/c1-18(19-6-4-3-5-7-19)30-26(32)16-31-15-23(21-10-13-24-25(14-21)37-17-36-24)27(29(33)34)28(31)20-8-11-22(35-2)12-9-20/h3-14,18,23,27-28H,15-17H2,1-2H3,(H,30,32)(H,33,34)/t18?,23-,27-,28+/m1/s1	KANHASGBLWIAIA-BXAOXKJXSA-N	50080611	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(1-phenyl-ethylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL121761	Endothelin-1 receptor			 5.5							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080611&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10649119	103980754		CHEMBL121761				ZINC13800420	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141204	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(CC(C)(C)C)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C33H38N2O6/c1-33(2,3)17-26(21-8-6-5-7-9-21)34-29(36)19-35-18-25(23-12-15-27-28(16-23)41-20-40-27)30(32(37)38)31(35)22-10-13-24(39-4)14-11-22/h5-16,25-26,30-31H,17-20H2,1-4H3,(H,34,36)(H,37,38)/t25-,26?,30-,31+/m1/s1	GQPZSZRJZWLIAV-BBVCMRRWSA-N	50080612	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(3,3-dimethyl-1-phenyl-butylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL122933	Endothelin-1 receptor			 131							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080612&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10816667	103980755		CHEMBL122933				ZINC27196067	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141205	CCc1ccccc1C(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1C	InChI=1S/C37H38N2O6/c1-4-24-10-6-8-12-29(24)35(28-11-7-5-9-23(28)2)38-33(40)21-39-20-30(26-15-18-31-32(19-26)45-22-44-31)34(37(41)42)36(39)25-13-16-27(43-3)17-14-25/h5-19,30,34-36H,4,20-22H2,1-3H3,(H,38,40)(H,41,42)/t30-,34-,35?,36+/m1/s1	VRQCDTCXZAZNSU-JYDDVVHLSA-N	50080613	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-({[(2-ethyl-phenyl)-o-tolyl-methyl]-carbamoyl}-methyl)-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL332424	Endothelin-1 receptor			 749							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080613&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10722389	103980756		CHEMBL332424				ZINC27196029	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141208	CCC(CC)C(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C33H38N2O6/c1-4-21(5-2)31(22-9-7-6-8-10-22)34-29(36)19-35-18-26(24-13-16-27-28(17-24)41-20-40-27)30(33(37)38)32(35)23-11-14-25(39-3)15-12-23/h6-17,21,26,30-32H,4-5,18-20H2,1-3H3,(H,34,36)(H,37,38)/t26-,30-,31?,32+/m1/s1	BSUWUKYJNUNGOM-CAMINTRRSA-N	50080616	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2-ethyl-1-phenyl-butylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL330895	Endothelin-1 receptor			 2.5							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080616&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10698065	103980759		CHEMBL330895				ZINC27193337	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141209	COCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C38H40N2O7/c1-24-8-4-6-10-29(24)36(30-11-7-5-9-25(30)2)39-34(41)22-40-21-31(27-14-17-32-33(20-27)47-23-46-32)35(38(42)43)37(40)26-12-15-28(16-13-26)45-19-18-44-3/h4-17,20,31,35-37H,18-19,21-23H2,1-3H3,(H,39,41)(H,42,43)/t31-,35-,37+/m1/s1	MAYFJXPGRYHMPF-WSQCMGDHSA-N	50080614	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylmethyl-carbamoyl)-methyl]-2-[4-(2-methoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123654	Endothelin-1 receptor			 27014							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080614&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10604119	103980757		CHEMBL123654				ZINC27198948	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141211	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C30H32N2O6/c1-18-6-4-5-7-23(18)19(2)31-27(33)16-32-15-24(21-10-13-25-26(14-21)38-17-37-25)28(30(34)35)29(32)20-8-11-22(36-3)12-9-20/h4-14,19,24,28-29H,15-17H2,1-3H3,(H,31,33)(H,34,35)/t19?,24-,28-,29+/m1/s1	QPZJVKVINGMRAL-MFYZVRTLSA-N	50080618	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(1-o-tolyl-ethylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123146	Endothelin-1 receptor			 16							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080618&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10815726	103980761		CHEMBL123146				ZINC27204107	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141215	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)c1cc(C)ccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C36H36N2O6/c1-22-9-10-23(2)28(17-22)34(24-7-5-4-6-8-24)37-32(39)20-38-19-29(26-13-16-30-31(18-26)44-21-43-30)33(36(40)41)35(38)25-11-14-27(42-3)15-12-25/h4-18,29,33-35H,19-21H2,1-3H3,(H,37,39)(H,40,41)/t29-,33-,34?,35+/m1/s1	YJMPVDOQESXRRN-FDFQOUNJSA-N	50080621	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-({[(2,5-dimethyl-phenyl)-phenyl-methyl]-carbamoyl}-methyl)-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL331548	Endothelin-1 receptor			 122							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080621&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10531506	103980764		CHEMBL331548				ZINC27194694	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141216	CC(C)OCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)C(C)(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C36H44N2O7/c1-23(2)42-17-18-43-27-14-11-24(12-15-27)33-32(35(40)41)28(26-13-16-29-30(19-26)45-22-44-29)20-38(33)21-31(39)37-34(36(3,4)5)25-9-7-6-8-10-25/h6-16,19,23,28,32-34H,17-18,20-22H2,1-5H3,(H,37,39)(H,40,41)/t28-,32-,33+,34?/m1/s1	UNUUFLTUZOLRDF-RRGMOPSSSA-N	50080623	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,2-dimethyl-1-phenyl-propylcarbamoyl)-methyl]-2-[4-(2-isopropoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL332289	Endothelin-1 receptor			 322							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080623&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10555806	103980766		CHEMBL332289				ZINC27195873	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141218	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(C(C)C)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C31H34N2O6/c1-19(2)29(20-7-5-4-6-8-20)32-27(34)17-33-16-24(22-11-14-25-26(15-22)39-18-38-25)28(31(35)36)30(33)21-9-12-23(37-3)13-10-21/h4-15,19,24,28-30H,16-18H2,1-3H3,(H,32,34)(H,35,36)/t24-,28-,29?,30+/m1/s1	DASGRKPWAFYAFD-YOJJAIPISA-N	50080622	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(2-methyl-1-phenyl-propylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL121647::CHEMBL366441	Endothelin-1 receptor			 0.7							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080622&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10720982	103980765		CHEMBL121647CHEMBL366441				ZINC27185918	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141220	COCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)C(C)(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C34H40N2O7/c1-34(2,3)32(23-8-6-5-7-9-23)35-29(37)20-36-19-26(24-12-15-27-28(18-24)43-21-42-27)30(33(38)39)31(36)22-10-13-25(14-11-22)41-17-16-40-4/h5-15,18,26,30-32H,16-17,19-21H2,1-4H3,(H,35,37)(H,38,39)/t26-,30-,31+,32?/m1/s1	WOQBGOSNHKHPRH-DZEKFYGQSA-N	50080624	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,2-dimethyl-1-phenyl-propylcarbamoyl)-methyl]-2-[4-(2-methoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123408	Endothelin-1 receptor			 488							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080624&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9808545	103980767		CHEMBL123408				ZINC27194884	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141221	CC(C)OCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C40H44N2O7/c1-25(2)46-19-20-47-30-16-13-28(14-17-30)39-37(40(44)45)33(29-15-18-34-35(21-29)49-24-48-34)22-42(39)23-36(43)41-38(31-11-7-5-9-26(31)3)32-12-8-6-10-27(32)4/h5-18,21,25,33,37-39H,19-20,22-24H2,1-4H3,(H,41,43)(H,44,45)/t33-,37-,39+/m1/s1	CMTKCIMTAINHTK-OMETZTOSSA-N	50080617	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylmethyl-carbamoyl)-methyl]-2-[4-(2-isopropoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL273642	Endothelin-1 receptor			 51700							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9961347	103980760		CHEMBL273642				ZINC03981332	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141230	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(CC(C)C)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C32H36N2O6/c1-20(2)15-26(21-7-5-4-6-8-21)33-29(35)18-34-17-25(23-11-14-27-28(16-23)40-19-39-27)30(32(36)37)31(34)22-9-12-24(38-3)13-10-22/h4-14,16,20,25-26,30-31H,15,17-19H2,1-3H3,(H,33,35)(H,36,37)/t25-,26?,30-,31+/m1/s1	HFWWOBMAMIJJEP-BBVCMRRWSA-N	50080620	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(3-methyl-1-phenyl-butylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL333034	Endothelin-1 receptor			 13.6							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080620&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10768904	103980763		CHEMBL333034				ZINC27194852	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141231	CCCCC(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C32H36N2O6/c1-3-4-10-26(21-8-6-5-7-9-21)33-29(35)19-34-18-25(23-13-16-27-28(17-23)40-20-39-27)30(32(36)37)31(34)22-11-14-24(38-2)15-12-22/h5-9,11-17,25-26,30-31H,3-4,10,18-20H2,1-2H3,(H,33,35)(H,36,37)/t25-,26?,30-,31+/m1/s1	FZJJZYJWWWMPOB-BBVCMRRWSA-N	50080629	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(1-phenyl-pentylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL334076	Endothelin-1 receptor			 1.6							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080629&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10768903	103980772		CHEMBL334076				ZINC27205029	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141233	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C35H34N2O6/c1-22-8-6-7-11-27(22)33(23-9-4-3-5-10-23)36-31(38)20-37-19-28(25-14-17-29-30(18-25)43-21-42-29)32(35(39)40)34(37)24-12-15-26(41-2)16-13-24/h3-18,28,32-34H,19-21H2,1-2H3,(H,36,38)(H,39,40)/t28-,32-,33?,34+/m1/s1	WYLRXEBBERTKHN-FQUYOTINSA-N	50080615	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-{[(phenyl-o-tolyl-methyl)-carbamoyl]-methyl}-pyrrolidine-3-carboxylic acid; TFA::CHEMBL432227	Endothelin-1 receptor			 63.5							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080615&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10555208	103980758		CHEMBL432227				ZINC27199159	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141234	CC(C)OCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C40H44N2O7/c1-25(2)46-19-20-47-30-16-13-28(14-17-30)39-37(40(44)45)33(29-15-18-34-35(21-29)49-24-48-34)22-42(39)23-36(43)41-38(31-11-7-5-9-26(31)3)32-12-8-6-10-27(32)4/h5-18,21,25,33,37-39H,19-20,22-24H2,1-4H3,(H,41,43)(H,44,45)/t33-,37-,39+/m1/s1	CMTKCIMTAINHTK-OMETZTOSSA-N	50080617	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylmethyl-carbamoyl)-methyl]-2-[4-(2-isopropoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL273642	Endothelin-1 receptor			 51703.0							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9961347	103980760		CHEMBL273642				ZINC03981332	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141235	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)C(C)(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C32H36N2O6/c1-32(2,3)30(21-8-6-5-7-9-21)33-27(35)18-34-17-24(22-12-15-25-26(16-22)40-19-39-25)28(31(36)37)29(34)20-10-13-23(38-4)14-11-20/h5-16,24,28-30H,17-19H2,1-4H3,(H,33,35)(H,36,37)/t24-,28-,29+,30?/m1/s1	NSVNTHSZOXQBPE-PABHLWBGSA-N	50080628	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,2-dimethyl-1-phenyl-propylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123316	Endothelin-1 receptor			 8.8							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080628&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10626362	103980771		CHEMBL123316				ZINC27199886	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141236	CCCC(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1	InChI=1S/C31H34N2O6/c1-3-7-25(20-8-5-4-6-9-20)32-28(34)18-33-17-24(22-12-15-26-27(16-22)39-19-38-26)29(31(35)36)30(33)21-10-13-23(37-2)14-11-21/h4-6,8-16,24-25,29-30H,3,7,17-19H2,1-2H3,(H,32,34)(H,35,36)/t24-,25?,29-,30+/m1/s1	NSROWKBSRVFCCQ-JIZVMTRLSA-N	50080626	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(1-phenyl-butylcarbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL331936	Endothelin-1 receptor			 3.7							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080626&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10697520	103980769		CHEMBL331936				ZINC27195972	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141239	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(Cc1ccccc1)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C35H34N2O6/c1-41-27-15-12-25(13-16-27)34-33(35(39)40)28(26-14-17-30-31(19-26)43-22-42-30)20-37(34)21-32(38)36-29(24-10-6-3-7-11-24)18-23-8-4-2-5-9-23/h2-17,19,28-29,33-34H,18,20-22H2,1H3,(H,36,38)(H,39,40)/t28-,29?,33-,34+/m1/s1	MRBWXOFHOJHYOZ-LPMROYQXSA-N	50080630	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(1,2-diphenyl-ethylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL122614::CHEMBL427303	Endothelin-1 receptor			 3.9							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080630&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10579100	103980773		CHEMBL427303CHEMBL122614				ZINC27198406	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141241	CCc1ccccc1C(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1CC	InChI=1S/C38H40N2O6/c1-4-24-10-6-8-12-29(24)36(30-13-9-7-11-25(30)5-2)39-34(41)22-40-21-31(27-16-19-32-33(20-27)46-23-45-32)35(38(42)43)37(40)26-14-17-28(44-3)18-15-26/h6-20,31,35-37H,4-5,21-23H2,1-3H3,(H,39,41)(H,42,43)/t31-,35-,37+/m1/s1	OTMGLEOGWQJHIQ-WSQCMGDHSA-N	50080634	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-({[bis-(2-ethyl-phenyl)-methyl]-carbamoyl}-methyl)-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL122673	Endothelin-1 receptor			 100							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080634&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10841576	103980777		CHEMBL122673				ZINC27196988	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141242	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m1/s1	MOTJMGVDPWRKOC-QPVYNBJUSA-N	50051007	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::A-127722::CHEMBL9194	Endothelin-1 receptor			 0.034							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			159594	103948098		CHEMBL9194				ZINC03812144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141243	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C40H36N2O6/c1-46-32-20-17-27(18-21-32)38-37(39(44)45)33(28-19-22-34-35(23-28)48-26-47-34)24-42(38)25-36(43)41-40(29-11-5-2-6-12-29,30-13-7-3-8-14-30)31-15-9-4-10-16-31/h2-23,33,37-38H,24-26H2,1H3,(H,41,43)(H,44,45)/t33-,37-,38+/m1/s1	VRCKDEMDFQJSQX-IVWQJUNXSA-N	50080633	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-1-[(trityl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL434986	Endothelin-1 receptor			 432.0							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080633&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10604167	103980776		CHEMBL434986				ZINC27198393	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141244	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C36H36N2O6/c1-22-8-4-6-10-27(22)34(28-11-7-5-9-23(28)2)37-32(39)20-38-19-29(25-14-17-30-31(18-25)44-21-43-30)33(36(40)41)35(38)24-12-15-26(42-3)16-13-24/h4-18,29,33-35H,19-21H2,1-3H3,(H,37,39)(H,40,41)/t29-,33-,35+/m1/s1	JYYUWMLSDGSJDK-DMOWINQSSA-N	50080619	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylmethyl-carbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL332109	Endothelin-1 receptor			 161							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080619&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10841170	103980762		CHEMBL332109				ZINC27197719	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141245	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C34H32N2O6/c1-40-26-15-12-24(13-16-26)33-31(34(38)39)27(25-14-17-28-29(18-25)42-21-41-28)19-36(33)20-30(37)35-32(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-18,27,31-33H,19-21H2,1H3,(H,35,37)(H,38,39)/t27-,31-,33+/m1/s1	GCISLFODTRCVKS-FLIPHLSNSA-N	50080625	(2R,3R,4S)-1-[(Benzhydryl-carbamoyl)-methyl]-4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123994	Endothelin-1 receptor			 45.9							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080625&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793053	103980768		CHEMBL123994				ZINC27195287	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141246	CCc1ccccc1C(NC(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OCCOC(C)C)cc1)C(O)=O)c1ccc2OCOc2c1)c1ccccc1C	InChI=1S/C41H46N2O7/c1-5-28-11-7-9-13-33(28)39(32-12-8-6-10-27(32)4)42-37(44)24-43-23-34(30-16-19-35-36(22-30)50-25-49-35)38(41(45)46)40(43)29-14-17-31(18-15-29)48-21-20-47-26(2)3/h6-19,22,26,34,38-40H,5,20-21,23-25H2,1-4H3,(H,42,44)(H,45,46)/t34-,38-,39?,40+/m1/s1	ITIIXFMHUJLFHC-NGCPSBGVSA-N	50080627	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-({[(2-ethyl-phenyl)-o-tolyl-methyl]-carbamoyl}-methyl)-2-[4-(2-isopropoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123206	Endothelin-1 receptor			 14270							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080627&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10723203	103980770		CHEMBL123206				ZINC27204120	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141247	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NCC(c1ccccc1)c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C35H34N2O6/c1-41-27-15-12-25(13-16-27)34-33(35(39)40)29(26-14-17-30-31(18-26)43-22-42-30)20-37(34)21-32(38)36-19-28(23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-18,28-29,33-34H,19-22H2,1H3,(H,36,38)(H,39,40)/t29-,33-,34+/m1/s1	XNUQKPOLJGKCNN-SJZCYFJVSA-N	50080632	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(2,2-diphenyl-ethylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL332808	Endothelin-1 receptor			 199							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080632&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10817024	103980775		CHEMBL332808				ZINC27198386	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141251	COc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC1c2ccccc2-c2ccccc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C34H30N2O6/c1-40-22-13-10-20(11-14-22)33-31(34(38)39)27(21-12-15-28-29(16-21)42-19-41-28)17-36(33)18-30(37)35-32-25-8-4-2-6-23(25)24-7-3-5-9-26(24)32/h2-16,27,31-33H,17-19H2,1H3,(H,35,37)(H,38,39)/t27-,31-,33+/m1/s1	LWFFJEUXOGFFKD-FLIPHLSNSA-N	50080631	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(9H-fluoren-9-ylcarbamoyl)-methyl]-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid; TFA::CHEMBL332144	Endothelin-1 receptor			 1228							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080631&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10650546	103980774		CHEMBL332144				ZINC27195166	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50141254	COCCOc1ccc(cc1)[C@H]1[C@@H]([C@H](CN1CC(=O)NC(c1ccccc1C)c1ccccc1C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C38H40N2O7/c1-24-8-4-6-10-29(24)36(30-11-7-5-9-25(30)2)39-34(41)22-40-21-31(27-14-17-32-33(20-27)47-23-46-32)35(38(42)43)37(40)26-12-15-28(16-13-26)45-19-18-44-3/h4-17,20,31,35-37H,18-19,21-23H2,1-3H3,(H,39,41)(H,42,43)/t31-,35-,37+/m1/s1	MAYFJXPGRYHMPF-WSQCMGDHSA-N	50080614	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-[(di-o-tolylmethyl-carbamoyl)-methyl]-2-[4-(2-methoxy-ethoxy)-phenyl]-pyrrolidine-3-carboxylic acid; TFA::CHEMBL123654	Endothelin-1 receptor			 27000							ChEMBL	10.1021/jm990171i	10.7270/Q2125RVT	10479299			Liu, G; Kozmina, NS; Winn, M; von Geldern, TW; Chiou, WJ; Dixon, DB; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50080614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50080614&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10604119	103980757		CHEMBL123654				ZINC27198948	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162809	CC(C)Cc1ccc(c(N)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C21H25N3O3S/c1-13(2)11-16-9-10-17(19(22)12-16)18-7-5-6-8-20(18)28(25,26)24-21-14(3)15(4)23-27-21/h5-10,12-13,24H,11,22H2,1-4H3	OZDIAVKCLFSBME-UHFFFAOYSA-N	50068674	2'-Amino-4'-isobutyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::2'-Amino-4'-isobutyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 187308)::BMS-187308::CHEMBL106684	Endothelin-1 receptor		 4.7								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068674&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9908909	103962866		CHEMBL106684				ZINC01488958	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162810	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cocn2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-20(13)23-28(24,25)19-6-4-3-5-17(19)15-7-9-16(10-8-15)18-11-26-12-21-18/h3-12,23H,1-2H3	BQEPLLPCPMRGBT-UHFFFAOYSA-N	50091101	4'-Oxazol-4-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL104848	Endothelin-1 receptor		 0.5								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11794992	103989489		CHEMBL104848				ZINC13809631	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162814	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncoc2C)c1C	InChI=1S/C21H19N3O4S/c1-13-14(2)23-28-21(13)24-29(25,26)19-7-5-4-6-18(19)16-8-10-17(11-9-16)20-15(3)27-12-22-20/h4-12,24H,1-3H3	QWBGYBQVMDWOBH-UHFFFAOYSA-N	50091106	4'-(5-Methyl-oxazol-4-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL104172	Endothelin-1 receptor		 4.7								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091106&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10811477	103989494		CHEMBL104172				ZINC13809633	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162816	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nc(C)c(C)o2)c1C	InChI=1S/C22H21N3O4S/c1-13-14(2)24-29-21(13)25-30(26,27)20-8-6-5-7-19(20)17-9-11-18(12-10-17)22-23-15(3)16(4)28-22/h5-12,25H,1-4H3	OJUNZBGNMUTVGC-UHFFFAOYSA-N	50091103	4'-(4,5-Dimethyl-oxazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL106749	Endothelin-1 receptor		 16								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091103&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740953	103989491		CHEMBL106749				ZINC13809628	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162819	Cc1cnc(o1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C21H19N3O4S/c1-13-12-22-21(27-13)17-10-8-16(9-11-17)18-6-4-5-7-19(18)29(25,26)24-20-14(2)15(3)23-28-20/h4-12,24H,1-3H3	JEXRIQLOSWSORT-UHFFFAOYSA-N	50091107	4'-(5-Methyl-oxazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL322674	Endothelin-1 receptor		 11								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091107&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740258	103989495		CHEMBL322674				ZINC13809627	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162820	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-26-20/h3-12,23H,1-2H3	LJGUZUROJOJEMI-UHFFFAOYSA-N	50091105	4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide::BMS-193884::CHEMBL24461	Endothelin-1 receptor		 1.4								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9843631	103989493		CHEMBL24461				ZINC00836695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162821	CC(=O)NCc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C23H22N4O5S/c1-14-15(2)26-32-22(14)27-33(29,30)21-7-5-4-6-20(21)19-9-8-17(23-24-10-11-31-23)12-18(19)13-25-16(3)28/h4-12,27H,13H2,1-3H3,(H,25,28)	XAHBFCGXCQNZHI-UHFFFAOYSA-N	50091104	CHEMBL29422::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-acetamide	Endothelin-1 receptor		 0.2								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091104&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11754273	103989492		CHEMBL29422				ZINC13492861	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162823	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(Cc3ncco3)cc2)c1C	InChI=1S/C21H19N3O4S/c1-14-15(2)23-28-21(14)24-29(25,26)19-6-4-3-5-18(19)17-9-7-16(8-10-17)13-20-22-11-12-27-20/h3-12,24H,13H2,1-2H3	BXIJQVAKFNNDBG-UHFFFAOYSA-N	50091102	4'-Oxazol-2-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL319924	Endothelin-1 receptor		 19								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091102&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10669224	103989490		CHEMBL319924				ZINC13809630	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162824	Cc1coc(n1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C21H19N3O4S/c1-13-12-27-21(22-13)17-10-8-16(9-11-17)18-6-4-5-7-19(18)29(25,26)24-20-14(2)15(3)23-28-20/h4-12,24H,1-3H3	JEJQDIYQQSISMV-UHFFFAOYSA-N	50091108	4'-(4-Methyl-oxazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL104223	Endothelin-1 receptor		 2								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091108&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10835335	103989496		CHEMBL104223				ZINC13809626	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162826	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor		 55								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162828	Cc1nc(co1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C21H19N3O4S/c1-13-14(2)23-28-21(13)24-29(25,26)20-7-5-4-6-18(20)16-8-10-17(11-9-16)19-12-27-15(3)22-19/h4-12,24H,1-3H3	NLXBGPMWVJISIR-UHFFFAOYSA-N	50091099	4'-(2-Methyl-oxazol-4-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL106846	Endothelin-1 receptor		 70								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091099&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10549472	103989487		CHEMBL106846				ZINC13809632	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162829	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cnco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-20(13)23-28(24,25)19-6-4-3-5-17(19)15-7-9-16(10-8-15)18-11-21-12-26-18/h3-12,23H,1-2H3	HZFREDAEPHMBSJ-UHFFFAOYSA-N	50091109	4'-Oxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL107574	Endothelin-1 receptor		 3.7								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091109&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10548722	103989497		CHEMBL107574				ZINC13809634	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162830	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nc3ccccc3o2)c1C	InChI=1S/C24H19N3O4S/c1-15-16(2)26-31-23(15)27-32(28,29)22-10-6-3-7-19(22)17-11-13-18(14-12-17)24-25-20-8-4-5-9-21(20)30-24/h3-14,27H,1-2H3	PYHQSADABPKIQL-UHFFFAOYSA-N	50091100	4'-Benzooxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL319036	Endothelin-1 receptor		 2000								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091100&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10813228	103989488		CHEMBL319036				ZINC13809629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50162831	CC(C)Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C21H24N2O3S/c1-14(2)13-17-9-11-18(12-10-17)19-7-5-6-8-20(19)27(24,25)23-21-15(3)16(4)22-26-21/h5-12,14,23H,13H2,1-4H3	BWTQPWDURQZRKQ-UHFFFAOYSA-N	50068742	4'-Isobutyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL105490	Endothelin-1 receptor		 18								ChEMBL	10.1021/jm000105c	10.7270/Q2DF6QFM	10956219			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Mathur, A; Leith, L; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Morrison, RA; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068742&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10691437	103962934		CHEMBL105490				ZINC13782414	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158569	C\C=C\C=C\C=C\C(=O)O[C@@H]1C=C2COC(=O)[C@]2(O)[C@@]2(C)CCCC(C)(C)C12	InChI=1S/C23H30O5/c1-5-6-7-8-9-11-18(24)28-17-14-16-15-27-20(25)23(16,26)22(4)13-10-12-21(2,3)19(17)22/h5-9,11,14,17,19,26H,10,12-13,15H2,1-4H3/b6-5+,8-7+,11-9+/t17-,19?,22+,23+/m1/s1	DPTZOOXIEWHODB-CMFMVBRPSA-N	50088848	(2E,4E,6E)-Octa-2,4,6-trienoic acid (5R,9aS,9bS)-9b-hydroxy-6,6,9a-trimethyl-1-oxo-1,3,5,5a,6,7,8,9,9a,9b-decahydro-naphtho[1,2-c]furan-5-yl ester::CHEMBL173059	Endothelin-1 receptor			 155000							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088848&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383592	103987719		CHEMBL173059				ZINC28011393	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158576	C\C=C\C=C\C=C\C(=O)O[C@@H]1C=C2COC(O)[C@]2(O)[C@@]2(C)CCCC(C)(C)C12	InChI=1S/C23H32O5/c1-5-6-7-8-9-11-18(24)28-17-14-16-15-27-20(25)23(16,26)22(4)13-10-12-21(2,3)19(17)22/h5-9,11,14,17,19-20,25-26H,10,12-13,15H2,1-4H3/b6-5+,8-7+,11-9+/t17-,19?,20?,22+,23+/m1/s1	BIBMODCOJDZAGU-ROOWPLTDSA-N	50088849	(2E,4E,6E)-Octa-2,4,6-trienoic acid (5R,9aS,9bS)-1,9b-dihydroxy-6,6,9a-trimethyl-1,3,5,5a,6,7,8,9,9a,9b-decahydro-naphtho[1,2-c]furan-5-yl ester::CHEMBL170335	Endothelin-1 receptor			 65000							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088849&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383537	103987720		CHEMBL170335				ZINC28001685	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158577	C\C=C\C=C\C(=O)O[C@H]1CC[C@@]2(O)C(=O)OCC2=C1	InChI=1S/C14H16O5/c1-2-3-4-5-12(15)19-11-6-7-14(17)10(8-11)9-18-13(14)16/h2-5,8,11,17H,6-7,9H2,1H3/b3-2+,5-4+/t11-,14-/m0/s1	IEVBPESGQHWAHK-DBZPTAEOSA-N	50088851	(2E,4E)-Hexa-2,4-dienoic acid (5S,7aS)-7a-hydroxy-1-oxo-1,3,5,6,7,7a-hexahydro-isobenzofuran-5-yl ester::CHEMBL170450	Endothelin-1 receptor			 2600							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088851&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10244529	103987722		CHEMBL170450				ZINC27999027	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158581	C\C=C\C=C\C(=O)O[C@H]1CC[C@@]2(O)C(O)OCC2=C1	InChI=1S/C14H18O5/c1-2-3-4-5-12(15)19-11-6-7-14(17)10(8-11)9-18-13(14)16/h2-5,8,11,13,16-17H,6-7,9H2,1H3/b3-2+,5-4+/t11-,13?,14-/m0/s1	VOXUGQBSDOYPIT-XSWSBQJESA-N	50088853	(2E,4E)-Hexa-2,4-dienoic acid (5S,7aS)-1,7a-dihydroxy-1,3,5,6,7,7a-hexahydro-isobenzofuran-5-yl ester::CHEMBL173336	Endothelin-1 receptor			 2500							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088853	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088853&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10038537	103987724		CHEMBL173336				ZINC28007255	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158582	COC1OCC2=C[C@H](CC[C@@]12O)OC(=O)\C=C\C=C\C	InChI=1S/C15H20O5/c1-3-4-5-6-13(16)20-12-7-8-15(17)11(9-12)10-19-14(15)18-2/h3-6,9,12,14,17H,7-8,10H2,1-2H3/b4-3+,6-5+/t12-,14?,15-/m0/s1	DPQLTVMQIFRVGZ-FJZFTCFBSA-N	50088852	(2E,4E)-Hexa-2,4-dienoic acid (5S,7aS)-7a-hydroxy-1-methoxy-1,3,5,6,7,7a-hexahydro-isobenzofuran-5-yl ester::CHEMBL170446	Endothelin-1 receptor			 8200.0							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088852&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383535	103987723		CHEMBL170446				ZINC28001145	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177616	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc3OCOc3c2)c1Cl	InChI=1S/C17H13ClN2O6S2/c1-9-15(18)17(26-19-9)20-28(22,23)14-4-5-27-16(14)11(21)6-10-2-3-12-13(7-10)25-8-24-12/h2-5,7,20H,6,8H2,1H3	GQABMKHWSKPQNS-UHFFFAOYSA-N	50058125	2-(2-Benzo[1,3]dioxol-5-yl-acetyl)-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL282470	Endothelin-1 receptor			 21							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058125&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10138169	103954104		CHEMBL282470				ZINC00601928	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177617	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc3OCOc3c2)c1Br	InChI=1S/C16H12BrN3O6S2/c1-8-13(17)16(26-19-8)20-28(22,23)12-4-5-27-14(12)15(21)18-9-2-3-10-11(6-9)25-7-24-10/h2-6,20H,7H2,1H3,(H,18,21)	JNCMNPQOJWALQJ-UHFFFAOYSA-N	50058086	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-ylamide::CHEMBL283136	Endothelin-1 receptor			 19							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058086&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10814776	103954065		CHEMBL283136				ZINC13815620	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177618	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)cc2C)c1Cl	InChI=1S/C18H18ClN3O4S2/c1-9-7-10(2)15(11(3)8-9)20-17(23)16-13(5-6-27-16)28(24,25)22-18-14(19)12(4)21-26-18/h5-8,22H,1-4H3,(H,20,23)	VMRGBLIETYGKNV-UHFFFAOYSA-N	50098772	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL277595	Endothelin-1 receptor			 0.17							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098772&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10717923	103995742		CHEMBL277595				ZINC13560310	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177619	CC(C)C(=O)c1cc(C)cc(C)c1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C21H22ClN3O5S2/c1-10(2)18(26)14-9-11(3)8-12(4)17(14)23-20(27)19-15(6-7-31-19)32(28,29)25-21-16(22)13(5)24-30-21/h6-10,25H,1-5H3,(H,23,27)	JWNRJKYXYXPAQY-UHFFFAOYSA-N	50098773	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-isobutyryl-4,6-dimethyl-phenyl)-amide::CHEMBL277706	Endothelin-1 receptor			 0.12							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098773&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10163744	103995743		CHEMBL277706				ZINC13560320	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177620	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2c(C)cc(C)c(O)c2C)c1Cl	InChI=1S/C19H19ClN2O5S2/c1-9-7-10(2)17(24)11(3)13(9)8-14(23)18-15(5-6-28-18)29(25,26)22-19-16(20)12(4)21-27-19/h5-7,22,24H,8H2,1-4H3	YHVRYVBITHJKNK-UHFFFAOYSA-N	50098774	2-[2-(3-Hydroxy-2,4,6-trimethyl-phenyl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL19921	Endothelin-1 receptor			 0.14							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098774&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10139080	103995744		CHEMBL19921				ZINC13801683	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177621	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2cc3OCOc3cc2C#N)c1Cl	InChI=1S/C17H11ClN4O6S2/c1-8-14(18)17(28-21-8)22-30(24,25)13-2-3-29-15(13)16(23)20-10-5-12-11(26-7-27-12)4-9(10)6-19/h2-5,22H,7H2,1H3,(H,20,23)	SFHTYTXFJBCUIC-UHFFFAOYSA-N	50058106	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-cyano-benzo[1,3]dioxol-5-yl)-amide::CHEMBL19808	Endothelin-1 receptor			 3.4							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058106&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10205245	103954085		CHEMBL19808				ZINC01544684	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177622	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc(C)cc2)c1Cl	InChI=1S/C16H14ClN3O4S2/c1-9-3-5-11(6-4-9)18-15(21)14-12(7-8-25-14)26(22,23)20-16-13(17)10(2)19-24-16/h3-8,20H,1-2H3,(H,18,21)	LONCVVCONRXSBM-UHFFFAOYSA-N	50058095	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolylamide::CHEMBL278114	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058095&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10811595	103954074		CHEMBL278114				ZINC00839629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177623	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)c(CC#N)c2C)c1C	InChI=1S/C21H22N4O4S2/c1-11-10-12(2)18(14(4)16(11)6-8-22)23-20(26)19-17(7-9-30-19)31(27,28)25-21-13(3)15(5)24-29-21/h7,9-10,25H,6H2,1-5H3,(H,23,26)	FMDCKBXKOAWRPM-UHFFFAOYSA-N	50098775	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (3-cyanomethyl-2,4,6-trimethyl-phenyl)-amide::CHEMBL279471	Endothelin-1 receptor			 0.17							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098775&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10623757	103995745		CHEMBL279471				ZINC13801694	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177624	CCc1cc(C)cc(C)c1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C19H20ClN3O4S2/c1-5-13-9-10(2)8-11(3)16(13)21-18(24)17-14(6-7-28-17)29(25,26)23-19-15(20)12(4)22-27-19/h6-9,23H,5H2,1-4H3,(H,21,24)	BEMRZVZLUSXULH-UHFFFAOYSA-N	50098776	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-ethyl-4,6-dimethyl-phenyl)-amide::CHEMBL283582	Endothelin-1 receptor			 0.43							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098776&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10182624	103995746		CHEMBL283582				ZINC13862562	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177625	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl	InChI=1S/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)20-27-18/h3-5,7,21H,6,8H2,1-2H3	PHWXUGHIIBDVKD-UHFFFAOYSA-N	50058126	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide (Sitaxsentan)::2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-5-methyl-benzoic acid isopropyl ester::CHEMBL282724::Sitaxentan	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058126&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			216235	103954105		CHEMBL282724	DB06268	3950		ZINC01481831	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177626	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)c(O)c2C)c1Cl	InChI=1S/C18H18ClN3O5S2/c1-8-7-9(2)15(23)10(3)14(8)20-17(24)16-12(5-6-28-16)29(25,26)22-18-13(19)11(4)21-27-18/h5-7,22-23H,1-4H3,(H,20,24)	CYMVGKIEVSAGJV-UHFFFAOYSA-N	50098779	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (3-hydroxy-2,4,6-trimethyl-phenyl)-amide::CHEMBL280659	Endothelin-1 receptor			 0.19							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098779&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9868637	103995749		CHEMBL280659				ZINC02008213	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177627	CC(=O)c1cc2OCOc2cc1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C18H14ClN3O7S2/c1-8-15(19)18(29-21-8)22-31(25,26)14-3-4-30-16(14)17(24)20-11-6-13-12(27-7-28-13)5-10(11)9(2)23/h3-6,22H,7H2,1-2H3,(H,20,24)	RKTQDYUICJAAKQ-UHFFFAOYSA-N	50058115	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (6-acetyl-benzo[1,3]dioxol-5-yl)-amide::CHEMBL283535	Endothelin-1 receptor			 10							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058115&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10696210	103954094		CHEMBL283535				ZINC01893329	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177628	CC(=O)c1cc(C)cc(C)c1NC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C19H18ClN3O5S2/c1-9-7-10(2)16(13(8-9)12(4)24)21-18(25)17-14(5-6-29-17)30(26,27)23-19-15(20)11(3)22-28-19/h5-8,23H,1-4H3,(H,21,25)	YFJUSGDKCDQMNE-UHFFFAOYSA-N	50098777	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2-acetyl-4,6-dimethyl-phenyl)-amide::CHEMBL19950	Endothelin-1 receptor			 0.04							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098777&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9934302	103995747		CHEMBL19950				ZINC01549959	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177629	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)c(CC#N)c2C)c1Cl	InChI=1S/C20H19ClN4O4S2/c1-10-9-11(2)17(12(3)14(10)5-7-22)23-19(26)18-15(6-8-30-18)31(27,28)25-20-16(21)13(4)24-29-20/h6,8-9,25H,5H2,1-4H3,(H,23,26)	KMHLVJAMVJZVMR-UHFFFAOYSA-N	50098778	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (3-cyanomethyl-2,4,6-trimethyl-phenyl)-amide::CHEMBL18626	Endothelin-1 receptor			 0.14							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098778&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10277399	103995748		CHEMBL18626				ZINC13801630	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177630	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1C	InChI=1S/C19H18N2O6S2/c1-10-6-15-16(26-9-25-15)8-13(10)7-14(22)18-17(4-5-28-18)29(23,24)21-19-11(2)12(3)20-27-19/h4-6,8,21H,7,9H2,1-3H3	ZKAHRYLIFLDFJH-UHFFFAOYSA-N	50058132	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL20168	Endothelin-1 receptor			 3.3							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058132&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10274552	103954111		CHEMBL20168				ZINC13815848	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50177631	Cc1onc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)c(CC#N)c2C)c1Cl	InChI=1S/C20H19ClN4O4S2/c1-10-9-11(2)17(12(3)14(10)5-7-22)23-20(26)18-15(6-8-30-18)31(27,28)25-19-16(21)13(4)29-24-19/h6,8-9H,5H2,1-4H3,(H,23,26)(H,24,25)	FBGBBRHEZOFDIS-UHFFFAOYSA-N	50098780	3-(4-Chloro-5-methyl-isoxazol-3-ylsulfamoyl)-thiophene-2-carboxylic acid (3-cyanomethyl-2,4,6-trimethyl-phenyl)-amide::CHEMBL19661	Endothelin-1 receptor			 0.1							ChEMBL	10.1021/jm000349x	10.7270/Q2Z89BN4	11312921			Wu, C; Decker, ER; Blok, N; Li, J; Bourgoyne, AR; Bui, H; Keller, KM; Knowles, V; Li, W; Stavros, FD; Holland, GW; Brock, TA; Dixon, RA	Texas Biotechnology Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098780&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10624511	103995750		CHEMBL19661				ZINC13801686	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50182999	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1O)c1ccc2OCOc2c1	InChI=1S/C26H25NO7/c1-3-32-17-6-7-18-20(11-17)26(19-8-5-16(31-2)12-21(19)28)27(13-24(29)30)25(18)15-4-9-22-23(10-15)34-14-33-22/h4-12,25-26,28H,3,13-14H2,1-2H3,(H,29,30)/t25-,26-/m1/s1	LDZGAMNZMSXJDP-CLJLJLNGSA-N	50101247	CHEMBL49850::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(2-hydroxy-4-methoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 77							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101247&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293736	103997942		CHEMBL49850				ZINC29468454	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183000	COc1ccc(cc1)[C@H]1N(CC(O)=O)[C@@H](c2ccc(OC)cc12)c1ccc2OCOc2c1	InChI=1S/C25H23NO6/c1-29-17-6-3-15(4-7-17)24-20-12-18(30-2)8-9-19(20)25(26(24)13-23(27)28)16-5-10-21-22(11-16)32-14-31-21/h3-12,24-25H,13-14H2,1-2H3,(H,27,28)/t24-,25-/m1/s1	RVYMZVMEZQKWSA-JWQCQUIFSA-N	50101248	CHEMBL297353::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-methoxy-3-(4-methoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 3300							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101248&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293716	103997943		CHEMBL297353				ZINC29411006	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183001	CCOc1ccc2[C@H](N([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)c1nnn[nH]1)c1ccc2OCOc2c1	InChI=1S/C27H25N5O7/c1-3-36-17-6-7-18-20(11-17)26(19-8-5-16(35-2)12-22(19)37-13-24(33)34)32(27-28-30-31-29-27)25(18)15-4-9-21-23(10-15)39-14-38-21/h4-12,25-26H,3,13-14H2,1-2H3,(H,33,34)(H,28,29,30,31)/t25-,26-/m1/s1	XSIBVUPCSKPMMH-CLJLJLNGSA-N	50101249	CHEMBL301371::{2-[(1S,3R)-3-Benzo[1,3]dioxol-5-yl-6-ethoxy-2-(1H-tetrazol-5-yl)-2,3-dihydro-1H-isoindol-1-yl]-5-methoxy-phenoxy}-acetic acid	Endothelin-1 receptor			 31							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101249&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293754	103997944		CHEMBL301371				ZINC29463076	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183002	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1OCC(C)(C)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C31H33NO9/c1-5-38-20-8-9-21-23(13-20)29(22-10-7-19(37-4)14-25(22)39-16-31(2,3)30(35)36)32(15-27(33)34)28(21)18-6-11-24-26(12-18)41-17-40-24/h6-14,28-29H,5,15-17H2,1-4H3,(H,33,34)(H,35,36)/t28-,29-/m1/s1	QALLWMCSGPPNCJ-FQLXRVMXSA-N	50101250	3-[2-((1S,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymethyl-6-ethoxy-2,3-dihydro-1H-isoindol-1-yl)-5-methoxy-phenoxy]-2,2-dimethyl-propionic acid::CHEMBL296974	Endothelin-1 receptor			 68							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101250&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293526	103997945		CHEMBL296974				ZINC29416857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183003	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1cccc(OC)c1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H27NO9/c1-3-35-17-8-9-18-20(12-17)27(19-5-4-6-22(34-2)28(19)36-14-25(32)33)29(13-24(30)31)26(18)16-7-10-21-23(11-16)38-15-37-21/h4-12,26-27H,3,13-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27-/m1/s1	PBTQECKJFWIROQ-KAYWLYCHSA-N	50101251	CHEMBL300000::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 85							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101251&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293685	103997946		CHEMBL300000				ZINC29467714	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183004	CCOc1ccc2[C@H](N([C@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H25NO10/c1-3-36-17-6-7-18-20(11-17)26(19-8-5-16(35-2)12-22(19)37-13-24(30)31)29(27(32)28(33)34)25(18)15-4-9-21-23(10-15)39-14-38-21/h4-12,25-26H,3,13-14H2,1-2H3,(H,30,31)(H,33,34)/t25-,26+/m1/s1	IRLDCHQLFYENIF-FTJBHMTQSA-N	50101252	CHEMBL432499::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-oxo-acetic acid	Endothelin-1 receptor			>10000							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101252&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293907	103997947		CHEMBL432499				ZINC29467769	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183005	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1cccc(OC)c1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H27NO9/c1-3-35-17-8-9-18-20(12-17)27(19-5-4-6-22(34-2)28(19)36-14-25(32)33)29(13-24(30)31)26(18)16-7-10-21-23(11-16)38-15-37-21/h4-12,26-27H,3,13-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27+/m1/s1	PBTQECKJFWIROQ-SXOMAYOGSA-N	50101253	CHEMBL417903::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 110							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101253&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293932	103997948		CHEMBL417903				ZINC29470084	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183006	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H29NO8/c1-5-35-18-7-8-19-20(13-18)27(17-11-23(32-2)28(34-4)24(12-17)33-3)29(14-25(30)31)26(19)16-6-9-21-22(10-16)37-15-36-21/h6-13,26-27H,5,14-15H2,1-4H3,(H,30,31)/t26-,27-/m1/s1	JBMMQCZBDFDLEC-KAYWLYCHSA-N	50101254	CHEMBL301723::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(3,4,5-trimethoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 66							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101254&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293927	103997949		CHEMBL301723				ZINC29464247	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183007	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1cc(OC)c(OC)c(OC)c1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H31NO11/c1-5-39-17-7-8-18-19(11-17)27(20-12-23(36-2)29(37-3)30(38-4)28(20)40-14-25(34)35)31(13-24(32)33)26(18)16-6-9-21-22(10-16)42-15-41-21/h6-12,26-27H,5,13-15H2,1-4H3,(H,32,33)(H,34,35)/t26-,27+/m1/s1	OMYYOJQBOHJVSD-SXOMAYOGSA-N	50101255	CHEMBL263723::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3,4,5-trimethoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 310							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101255&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293719	103997950		CHEMBL263723				ZINC29410679	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183008	CCOc1ccc2[C@H](N([C@H](c2c1)c1cc(OC)c(OC)c(OC)c1)c1nnn[nH]1)c1ccc2OCOc2c1	InChI=1S/C27H27N5O6/c1-5-36-17-7-8-18-19(13-17)25(16-11-22(33-2)26(35-4)23(12-16)34-3)32(27-28-30-31-29-27)24(18)15-6-9-20-21(10-15)38-14-37-20/h6-13,24-25H,5,14H2,1-4H3,(H,28,29,30,31)/t24-,25+/m1/s1	DNHOXWUVWOEOHX-RPBOFIJWSA-N	50101256	(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-2-(1H-tetrazol-5-yl)-3-(3,4,5-trimethoxy-phenyl)-2,3-dihydro-1H-isoindole::CHEMBL430759	Endothelin-1 receptor			>10000							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101256&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293547	103997951		CHEMBL430759				ZINC29412039	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183010	CCOc1ccc2[C@H](N([C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H25NO10/c1-3-36-17-6-7-18-20(11-17)26(19-8-5-16(35-2)12-22(19)37-13-24(30)31)29(27(32)28(33)34)25(18)15-4-9-21-23(10-15)39-14-38-21/h4-12,25-26H,3,13-14H2,1-2H3,(H,30,31)(H,33,34)/t25-,26-/m1/s1	IRLDCHQLFYENIF-CLJLJLNGSA-N	50101259	CHEMBL298212::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-oxo-acetic acid	Endothelin-1 receptor			 12							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101259&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915095	103997954		CHEMBL298212				ZINC29415831	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183011	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H27NO9/c1-3-35-18-6-7-19-21(11-18)28(20-8-5-17(34-2)12-23(20)36-14-26(32)33)29(13-25(30)31)27(19)16-4-9-22-24(10-16)38-15-37-22/h4-12,27-28H,3,13-15H2,1-2H3,(H,30,31)(H,32,33)/t27-,28-/m1/s1	IJOSJBQROXKMOT-VSGBNLITSA-N	50101258	CHEMBL295440::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 5.4							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9984193	103997953		CHEMBL295440				ZINC29416505	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183012	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1)c1ccc2OCOc2c1	InChI=1S/C26H25NO6/c1-3-31-19-9-10-20-21(13-19)25(16-4-7-18(30-2)8-5-16)27(14-24(28)29)26(20)17-6-11-22-23(12-17)33-15-32-22/h4-13,25-26H,3,14-15H2,1-2H3,(H,28,29)/t25-,26-/m1/s1	RAMHCNBQMDDFCA-CLJLJLNGSA-N	50101263	CHEMBL49040::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-methoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 96							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293741	103997958		CHEMBL49040				ZINC29464321	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183013	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)cc1OCC(C)(C)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C31H33NO9/c1-5-38-20-8-9-21-23(13-20)29(22-10-7-19(37-4)14-25(22)39-16-31(2,3)30(35)36)32(15-27(33)34)28(21)18-6-11-24-26(12-18)41-17-40-24/h6-14,28-29H,5,15-17H2,1-4H3,(H,33,34)(H,35,36)/t28-,29+/m1/s1	QALLWMCSGPPNCJ-WDYNHAJCSA-N	50101262	3-[2-((1R,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymethyl-6-ethoxy-2,3-dihydro-1H-isoindol-1-yl)-5-methoxy-phenoxy]-2,2-dimethyl-propionic acid::CHEMBL49312	Endothelin-1 receptor			 14							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293417	103997957		CHEMBL49312				ZINC29465147	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183014	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)cc1)c1ccc2OCOc2c1	InChI=1S/C26H25NO6/c1-3-31-19-9-10-20-21(13-19)25(16-4-7-18(30-2)8-5-16)27(14-24(28)29)26(20)17-6-11-22-23(12-17)33-15-32-22/h4-13,25-26H,3,14-15H2,1-2H3,(H,28,29)/t25-,26+/m0/s1	RAMHCNBQMDDFCA-IZZNHLLZSA-N	50101260	CHEMBL48652::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(4-methoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 95							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293682	103997955		CHEMBL48652				ZINC29466738	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183015	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1OCc1nnn[nH]1)c1ccc2OCOc2c1	InChI=1S/C28H27N5O7/c1-3-37-18-6-7-19-21(11-18)28(20-8-5-17(36-2)12-23(20)38-14-25-29-31-32-30-25)33(13-26(34)35)27(19)16-4-9-22-24(10-16)40-15-39-22/h4-12,27-28H,3,13-15H2,1-2H3,(H,34,35)(H,29,30,31,32)/t27-,28-/m1/s1	DKZVMSFPFHQYJP-VSGBNLITSA-N	50101261	CHEMBL295140::{(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[4-methoxy-2-(1H-tetrazol-5-ylmethoxy)-phenyl]-1,3-dihydro-isoindol-2-yl}-acetic acid	Endothelin-1 receptor			 29							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101261&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293805	103997956		CHEMBL295140				ZINC29465571	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183016	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)c(OC)c1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H29NO10/c1-4-37-17-6-7-18-20(12-17)27(19-8-10-22(35-2)29(36-3)28(19)38-14-25(33)34)30(13-24(31)32)26(18)16-5-9-21-23(11-16)40-15-39-21/h5-12,26-27H,4,13-15H2,1-3H3,(H,31,32)(H,33,34)/t26-,27+/m1/s1	AEBFVYQCTDATBZ-SXOMAYOGSA-N	50101264	CHEMBL298664::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3,4-dimethoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 96							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293868	103997959		CHEMBL298664				ZINC29469476	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183017	CCCOc1ccc2[C@H]([C@@H]([C@H](c2c1)c1ccc(OC)cc1OCC(O)=O)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H28O9/c1-3-10-35-18-6-7-19-21(12-18)27(20-8-5-17(34-2)13-23(20)36-14-25(30)31)28(29(32)33)26(19)16-4-9-22-24(11-16)38-15-37-22/h4-9,11-13,26-28H,3,10,14-15H2,1-2H3,(H,30,31)(H,32,33)/t26-,27+,28+/m1/s1	UUAVCCWBNUITBB-PKTNWEFCSA-N	50101257	(1R,2S,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-propoxy-indan-2-carboxylic acid::CHEMBL48196	Endothelin-1 receptor		 0.430000								ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9849547	103997952		CHEMBL48196				ZINC01887086	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183018	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1OCCO)c1ccc2OCOc2c1	InChI=1S/C28H29NO8/c1-3-34-19-6-7-20-22(13-19)28(21-8-5-18(33-2)14-24(21)35-11-10-30)29(15-26(31)32)27(20)17-4-9-23-25(12-17)37-16-36-23/h4-9,12-14,27-28,30H,3,10-11,15-16H2,1-2H3,(H,31,32)/t27-,28-/m1/s1	SIKCHHQFRMPLOK-VSGBNLITSA-N	50101265	CHEMBL298569::{(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[2-(2-hydroxy-ethoxy)-4-methoxy-phenyl]-1,3-dihydro-isoindol-2-yl}-acetic acid	Endothelin-1 receptor			>10000							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293702	103997960		CHEMBL298569				ZINC29417487	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183019	CCCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1)c1ccc(OC)cc1OCC(O)=O	InChI=1S/C29H31NO8/c1-4-13-37-21-10-11-22-24(14-21)28(18-5-7-19(35-2)8-6-18)30(16-26(31)32)29(22)23-12-9-20(36-3)15-25(23)38-17-27(33)34/h5-12,14-15,28-29H,4,13,16-17H2,1-3H3,(H,31,32)(H,33,34)/t28-,29+/m1/s1	WOLXOYFHGNIFKF-WDYNHAJCSA-N	50101266	CHEMBL47563::[(1S,3R)-1-(2-Carboxymethoxy-4-methoxy-phenyl)-3-(4-methoxy-phenyl)-5-propoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			>10000							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293661	103997961		CHEMBL47563				ZINC29412342	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183020	CCCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1)c1ccc2OCOc2c1	InChI=1S/C27H27NO6/c1-3-12-32-20-9-10-21-22(14-20)26(17-4-7-19(31-2)8-5-17)28(15-25(29)30)27(21)18-6-11-23-24(13-18)34-16-33-23/h4-11,13-14,26-27H,3,12,15-16H2,1-2H3,(H,29,30)/t26-,27-/m1/s1	QEYNQJBCFCUMCK-KAYWLYCHSA-N	50101269	CHEMBL298922::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(4-methoxy-phenyl)-5-propoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 120							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101269&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293866	103997964		CHEMBL298922				ZINC29469467	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183021	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)cc1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H27NO9/c1-3-35-18-6-7-19-21(11-18)28(20-8-5-17(34-2)12-23(20)36-14-26(32)33)29(13-25(30)31)27(19)16-4-9-22-24(10-16)38-15-37-22/h4-12,27-28H,3,13-15H2,1-2H3,(H,30,31)(H,32,33)/t27-,28+/m1/s1	IJOSJBQROXKMOT-IZLXSDGUSA-N	50101268	CHEMBL50232::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-4-methoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 4.1							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101268&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10391968	103997963		CHEMBL50232				ZINC29465959	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183022	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H29NO8/c1-5-35-18-7-8-19-20(13-18)27(17-11-23(32-2)28(34-4)24(12-17)33-3)29(14-25(30)31)26(19)16-6-9-21-22(10-16)37-15-36-21/h6-13,26-27H,5,14-15H2,1-4H3,(H,30,31)/t26-,27+/m1/s1	JBMMQCZBDFDLEC-SXOMAYOGSA-N	50101267	CHEMBL52110::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(3,4,5-trimethoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 1100							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293915	103997962		CHEMBL52110				ZINC29473590	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183023	CCCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)cc1)c1ccc(OC)cc1OCC(O)=O	InChI=1S/C29H31NO8/c1-4-13-37-21-10-11-22-24(14-21)28(18-5-7-19(35-2)8-6-18)30(16-26(31)32)29(22)23-12-9-20(36-3)15-25(23)38-17-27(33)34/h5-12,14-15,28-29H,4,13,16-17H2,1-3H3,(H,31,32)(H,33,34)/t28-,29-/m0/s1	WOLXOYFHGNIFKF-VMPREFPWSA-N	50101270	CHEMBL49007::[(1S,3S)-1-(2-Carboxymethoxy-4-methoxy-phenyl)-3-(4-methoxy-phenyl)-5-propoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			>10000							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101270&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293681	103997965		CHEMBL49007				ZINC29467851	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183024	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)cc1O)c1ccc2OCOc2c1	InChI=1S/C26H25NO7/c1-3-32-17-6-7-18-20(11-17)26(19-8-5-16(31-2)12-21(19)28)27(13-24(29)30)25(18)15-4-9-22-23(10-15)34-14-33-22/h4-12,25-26,28H,3,13-14H2,1-2H3,(H,29,30)/t25-,26+/m1/s1	LDZGAMNZMSXJDP-FTJBHMTQSA-N	50101274	CHEMBL430572::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-(2-hydroxy-4-methoxy-phenyl)-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 58							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101274&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293631	103997969		CHEMBL430572				ZINC29467966	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183025	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)cc1OCCCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H31NO9/c1-3-37-20-8-9-21-23(14-20)30(22-10-7-19(36-2)15-25(22)38-12-4-5-27(32)33)31(16-28(34)35)29(21)18-6-11-24-26(13-18)40-17-39-24/h6-11,13-15,29-30H,3-5,12,16-17H2,1-2H3,(H,32,33)(H,34,35)/t29-,30-/m1/s1	LHIXARGYJZGGRY-LOYHVIPDSA-N	50101275	4-[2-((1S,3R)-3-Benzo[1,3]dioxol-5-yl-2-carboxymethyl-6-ethoxy-2,3-dihydro-1H-isoindol-1-yl)-5-methoxy-phenoxy]-butyric acid::CHEMBL440853	Endothelin-1 receptor			 22							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101275&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293761	103997970		CHEMBL440853				ZINC29414805	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183026	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)cc1OCc1nnn[nH]1)c1ccc2OCOc2c1	InChI=1S/C28H27N5O7/c1-3-37-18-6-7-19-21(11-18)28(20-8-5-17(36-2)12-23(20)38-14-25-29-31-32-30-25)33(13-26(34)35)27(19)16-4-9-22-24(10-16)40-15-39-22/h4-12,27-28H,3,13-15H2,1-2H3,(H,34,35)(H,29,30,31,32)/t27-,28+/m1/s1	DKZVMSFPFHQYJP-IZLXSDGUSA-N	50101272	CHEMBL299095::{(1R,3R)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[4-methoxy-2-(1H-tetrazol-5-ylmethoxy)-phenyl]-1,3-dihydro-isoindol-2-yl}-acetic acid	Endothelin-1 receptor			>1000							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101272&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293825	103997967		CHEMBL299095				ZINC29464255	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183027	CCOc1ccc2[C@H](N(CC(O)=O)[C@@H](c2c1)c1ccc(OC)c(OC)c1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H29NO10/c1-4-37-17-6-7-18-20(12-17)27(19-8-10-22(35-2)29(36-3)28(19)38-14-25(33)34)30(13-24(31)32)26(18)16-5-9-21-23(11-16)40-15-39-21/h5-12,26-27H,4,13-15H2,1-3H3,(H,31,32)(H,33,34)/t26-,27-/m1/s1	AEBFVYQCTDATBZ-KAYWLYCHSA-N	50101271	CHEMBL47868::[(1R,3S)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3,4-dimethoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 6.1							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101271&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293720	103997966		CHEMBL47868				ZINC29410976	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50183028	CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1cc(OC)c(OC)c(OC)c1OCC(O)=O)c1ccc2OCOc2c1	InChI=1S/C30H31NO11/c1-5-39-17-7-8-18-19(11-17)27(20-12-23(36-2)29(37-3)30(38-4)28(20)40-14-25(34)35)31(13-24(32)33)26(18)16-6-9-21-22(10-16)42-15-41-21/h6-12,26-27H,5,13-15H2,1-4H3,(H,32,33)(H,34,35)/t26-,27-/m1/s1	OMYYOJQBOHJVSD-KAYWLYCHSA-N	50101273	CHEMBL48261::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3,4,5-trimethoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid	Endothelin-1 receptor			 330							ChEMBL	10.1016/s0960-894x(01)00273-6	10.7270/Q2B27TJ5	11425549			Kukkola, PJ; Bilci, NA; Ikler, T; Savage, P; Shetty, SS; DelGrande, D; Jeng, AY	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50101273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50101273&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44293813	103997968		CHEMBL48261				ZINC29468064	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198908	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nnco2)c1C	InChI=1S/C19H16N4O4S/c1-12-13(2)22-27-18(12)23-28(24,25)17-6-4-3-5-16(17)14-7-9-15(10-8-14)19-21-20-11-26-19/h3-11,23H,1-2H3	UYEFZFPSIRPMNJ-UHFFFAOYSA-N	50109659	4'-[1,3,4]Oxadiazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL357077	Endothelin-1 receptor		 4								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109659&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22103385	104004598		CHEMBL357077				ZINC01487119	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198911	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncc[nH]2)c1C	InChI=1S/C20H18N4O3S/c1-13-14(2)23-27-20(13)24-28(25,26)18-6-4-3-5-17(18)15-7-9-16(10-8-15)19-21-11-12-22-19/h3-12,24H,1-2H3,(H,21,22)	FNTMFRCZIVZTGK-UHFFFAOYSA-N	50109661	4'-(1H-Imidazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL148855	Endothelin-1 receptor		 44								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109661&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22103589	104004600		CHEMBL148855				ZINC13437965	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198912	Cc1[n-][o+]c(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cccc[n+]2[O-])c1C	InChI=1S/C22H19N3O4S/c1-15-16(2)23-29-22(15)24-30(27,28)21-9-4-3-7-19(21)17-10-12-18(13-11-17)20-8-5-6-14-25(20)26/h3-14,24H,1-2H3	AITOTEQUPDSIJB-UHFFFAOYSA-N	50109662	4'-(1-Oxy-pyridin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL147238	Endothelin-1 receptor		 37								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109662&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44213540	104004601		CHEMBL147238				ZINC00838998	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198913	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-n2cccn2)c1C	InChI=1S/C20H18N4O3S/c1-14-15(2)22-27-20(14)23-28(25,26)19-7-4-3-6-18(19)16-8-10-17(11-9-16)24-13-5-12-21-24/h3-13,23H,1-2H3	FSKHGCPUJBTSRI-UHFFFAOYSA-N	50109663	4'-Pyrazol-1-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL148719	Endothelin-1 receptor		 6.7								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109663&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22103787	104004602		CHEMBL148719				ZINC13437972	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198915	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cncnc2)c1C	InChI=1S/C21H18N4O3S/c1-14-15(2)24-28-21(14)25-29(26,27)20-6-4-3-5-19(20)17-9-7-16(8-10-17)18-11-22-13-23-12-18/h3-13,25H,1-2H3	ZKNCHNYMKZIRER-UHFFFAOYSA-N	50109665	4'-Pyrimidin-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149340	Endothelin-1 receptor		 300								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109665&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18660523	104004604		CHEMBL149340				ZINC00838996	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198916	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncccn2)c1C	InChI=1S/C21H18N4O3S/c1-14-15(2)24-28-21(14)25-29(26,27)19-7-4-3-6-18(19)16-8-10-17(11-9-16)20-22-12-5-13-23-20/h3-13,25H,1-2H3	AZYAXQRVKZNKCU-UHFFFAOYSA-N	50109666	4'-Pyrimidin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL359273	Endothelin-1 receptor		 0.900000								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109666&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9822616	104004605		CHEMBL359273				ZINC00601847	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198918	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccccn2)c1C	InChI=1S/C22H19N3O3S/c1-15-16(2)24-28-22(15)25-29(26,27)21-9-4-3-7-19(21)17-10-12-18(13-11-17)20-8-5-6-14-23-20/h3-14,25H,1-2H3	DGNMDJFSXFSHGR-UHFFFAOYSA-N	50109667	4'-Pyridin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149232	Endothelin-1 receptor		 2.3								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109667&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18660521	104004606		CHEMBL149232				ZINC00838986	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198920	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccncn2)c1C	InChI=1S/C21H18N4O3S/c1-14-15(2)24-28-21(14)25-29(26,27)20-6-4-3-5-18(20)16-7-9-17(10-8-16)19-11-12-22-13-23-19/h3-13,25H,1-2H3	OXPDZJBNFCQMDY-UHFFFAOYSA-N	50109660	4'-Pyrimidin-4-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL346862	Endothelin-1 receptor		 25								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109660&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18660522	104004599		CHEMBL346862				ZINC00838992	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198924	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nnn[nH]2)c1C	InChI=1S/C18H16N6O3S/c1-11-12(2)21-27-18(11)22-28(25,26)16-6-4-3-5-15(16)13-7-9-14(10-8-13)17-19-23-24-20-17/h3-10,22H,1-2H3,(H,19,20,23,24)	GIPHHFOUPLKPNT-UHFFFAOYSA-N	50109669	4'-(1H-Tetrazol-5-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149778	Endothelin-1 receptor		 3800								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109669&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44365878	104004608		CHEMBL149778				ZINC13437986	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198925	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cccnc2)c1C	InChI=1S/C22H19N3O3S/c1-15-16(2)24-28-22(15)25-29(26,27)21-8-4-3-7-20(21)18-11-9-17(10-12-18)19-6-5-13-23-14-19/h3-14,25H,1-2H3	DUTMOISDZUUDON-UHFFFAOYSA-N	50109670	4'-Pyridin-3-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL345951	Endothelin-1 receptor		 3.3								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109670&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19085510	104004609		CHEMBL345951				ZINC00838988	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198927	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2cnccn2)c1C	InChI=1S/C21H18N4O3S/c1-14-15(2)24-28-21(14)25-29(26,27)20-6-4-3-5-18(20)16-7-9-17(10-8-16)19-13-22-11-12-23-19/h3-13,25H,1-2H3	UVYXPSDNXLRANG-UHFFFAOYSA-N	50109664	4'-Pyrazin-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL147340	Endothelin-1 receptor		 6.2								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109664&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18660520	104004603		CHEMBL147340				ZINC00838994	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198929	COc1cc(OC)nc(n1)-c1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C23H22N4O5S/c1-14-15(2)26-32-23(14)27-33(28,29)19-8-6-5-7-18(19)16-9-11-17(12-10-16)22-24-20(30-3)13-21(25-22)31-4/h5-13,27H,1-4H3	PBQXMKQAIAUNQN-UHFFFAOYSA-N	50109671	4'-(4,6-Dimethoxy-pyrimidin-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL147365	Endothelin-1 receptor		 220								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109671&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19085508	104004610		CHEMBL147365				ZINC00838990	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198933	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nccn2C)c1C	InChI=1S/C21H20N4O3S/c1-14-15(2)23-28-21(14)24-29(26,27)19-7-5-4-6-18(19)16-8-10-17(11-9-16)20-22-12-13-25(20)3/h4-13,24H,1-3H3	SMFAJSYEZREKBY-UHFFFAOYSA-N	50109672	4'-(1-Methyl-1H-imidazol-2-yl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149010	Endothelin-1 receptor		 19								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109672&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22103797	104004611		CHEMBL149010				ZINC13437968	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198934	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-26-20/h3-12,23H,1-2H3	LJGUZUROJOJEMI-UHFFFAOYSA-N	50091105	4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide::BMS-193884::CHEMBL24461	Endothelin-1 receptor		 1.4								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9843631	103989493		CHEMBL24461				ZINC00836695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198935	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccccc2)c1C	InChI=1S/C23H20N2O3S/c1-16-17(2)24-28-23(16)25-29(26,27)22-11-7-6-10-21(22)20-14-12-19(13-15-20)18-8-4-3-5-9-18/h3-15,25H,1-2H3	OOPZGJDTSUDOLS-UHFFFAOYSA-N	50109673	CHEMBL149763::[1,1';4',1'']Terphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide	Endothelin-1 receptor		 38								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109673&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44365561	104004612		CHEMBL149763				ZINC13437992	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198938	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ccno2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-20(13)23-28(24,25)19-6-4-3-5-17(19)15-7-9-16(10-8-15)18-11-12-21-26-18/h3-12,23H,1-2H3	YBRONYXWWAUIFR-UHFFFAOYSA-N	50109674	4'-Isoxazol-5-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL149592	Endothelin-1 receptor		 270								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109674&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22103537	104004613		CHEMBL149592				ZINC13437978	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50198940	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2nccs2)c1C	InChI=1S/C20H17N3O3S2/c1-13-14(2)22-26-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-27-20/h3-12,23H,1-2H3	KKLQZLPUGNIANZ-UHFFFAOYSA-N	50109668	4'-Thiazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL150260	Endothelin-1 receptor		 5.6								ChEMBL	10.1016/s0960-894x(01)00791-0	10.7270/Q2GF0STQ	11844662			Murugesan, N; Gu, Z; Stein, PD; Spergel, S; Bisaha, S; Liu, EC; Zhang, R; Webb, ML; Moreland, S; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109668&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22103743	104004607		CHEMBL150260				ZINC13437961	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50204467	COc1ccc(cc1)C1=C([C@H](Oc2ccc(OC(C)C)cc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C27H24O7/c1-15(2)33-19-9-11-21-20(13-19)24(16-4-7-18(30-3)8-5-16)25(27(28)29)26(34-21)17-6-10-22-23(12-17)32-14-31-22/h4-13,15,26H,14H2,1-3H3,(H,28,29)/t26-/m1/s1	BATSJXIVNKJCKQ-AREMUKBSSA-N	50112678	(R)-2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-phenyl)-2H-chromene-3-carboxylic acid::2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(4-methoxy-phenyl)-2H-chromene-3-carboxylic acid::CHEMBL61211	Endothelin-1 receptor			 0.45							ChEMBL	10.1021/jm010382z	10.7270/Q24J0DGM	11985472			Ishizuka, N; Matsumura, K; Sakai, K; Fujimoto, M; Mihara, S; Yamamori, T	Shionogi & Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112678&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9825494	104007076		CHEMBL61211					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196004	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccc(cc12)C(=O)OC	InChI=1S/C30H30N2O7S/c1-5-32-16-24(23-12-8-21(14-25(23)32)30(34)37-4)28(20-9-13-26-27(15-20)39-17-38-26)29(33)31-40(35,36)22-10-6-19(7-11-22)18(2)3/h6-16,18,28H,5,17H2,1-4H3,(H,31,33)	AXDHCWCWSPYZIW-UHFFFAOYSA-N	50108186	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid methyl ester::CHEMBL23418	Endothelin-1 receptor			 210							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108186&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738889	104003407		CHEMBL23418				ZINC28263161	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196005	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C28H27N3O6S/c1-16(2)17-4-8-20(9-5-17)38(34,35)30-28(33)26(18-7-11-24-25(13-18)37-15-36-24)22-14-31(3)23-12-19(27(29)32)6-10-21(22)23/h4-14,16,26H,15H2,1-3H3,(H2,29,32)(H,30,33)	MWZFOVILFVOLMJ-UHFFFAOYSA-N	50108187	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid::3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL262784	Endothelin-1 receptor			 2.3							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467235	104003408		CHEMBL262784				ZINC28257415	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196006	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccc(cc12)C(=O)N(C)C	InChI=1S/C31H33N3O6S/c1-6-34-17-25(24-13-9-22(15-26(24)34)31(36)33(4)5)29(21-10-14-27-28(16-21)40-18-39-27)30(35)32-41(37,38)23-11-7-20(8-12-23)19(2)3/h7-17,19,29H,6,18H2,1-5H3,(H,32,35)	HEGRKFSINVTUKI-UHFFFAOYSA-N	50108189	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid dimethylamide::CHEMBL23444	Endothelin-1 receptor			 72							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108189&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44459247	104003410		CHEMBL23444				ZINC28265032	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196008	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1c[nH]c2cc(ccc12)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H24N2O7S/c1-15(2)16-3-7-19(8-4-16)37(33,34)29-26(30)25(17-6-10-23-24(12-17)36-14-35-23)21-13-28-22-11-18(27(31)32)5-9-20(21)22/h3-13,15,25,28H,14H2,1-2H3,(H,29,30)(H,31,32)	SOCSMFJUOGUBKQ-UHFFFAOYSA-N	50108190	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1H-indole-6-carboxylic acid::CHEMBL23752	Endothelin-1 receptor			 31							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108190&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44459299	104003411		CHEMBL23752				ZINC13436374	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196009	Cn1cc(C(C(=O)NS(=O)(=O)c2ccccc2C(O)=O)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O	InChI=1S/C26H21N3O8S/c1-29-12-18(16-8-6-15(24(27)30)10-19(16)29)23(14-7-9-20-21(11-14)37-13-36-20)25(31)28-38(34,35)22-5-3-2-4-17(22)26(32)33/h2-12,23H,13H2,1H3,(H2,27,30)(H,28,31)(H,32,33)	RDFPZCGBCKZXNO-UHFFFAOYSA-N	50108193	2-[2-Benzo[1,3]dioxol-5-yl-2-(6-carbamoyl-1-methyl-1H-indol-3-yl)-acetylsulfamoyl]-benzoic acid::CHEMBL278349	Endothelin-1 receptor			 3.1							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108193&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458597	104003414		CHEMBL278349				ZINC28257497	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196010	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C27H25N3O7S/c1-15-4-9-24(23(10-15)35-3)38(33,34)29-27(32)25(16-6-8-21-22(12-16)37-14-36-21)19-13-30(2)20-11-17(26(28)31)5-7-18(19)20/h4-13,25H,14H2,1-3H3,(H2,28,31)(H,29,32)	XSSAXXJNGRXQCR-UHFFFAOYSA-N	50108192	3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22562	Endothelin-1 receptor			 1.1							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108192&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347080	104003413		CHEMBL22562				ZINC28258137	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196011	COc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C26H23N3O7S/c1-29-13-18(17-9-7-16(25(27)30)11-19(17)29)24(15-8-10-20-22(12-15)36-14-35-20)26(31)28-37(32,33)23-6-4-3-5-21(23)34-2/h3-13,24H,14H2,1-2H3,(H2,27,30)(H,28,31)	BOZMVLDNYMRJIR-UHFFFAOYSA-N	50108191	3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22367	Endothelin-1 receptor			 5							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108191&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458650	104003412		CHEMBL22367				ZINC13436419	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196012	Cn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O	InChI=1S/C26H20F3N3O6S/c1-32-12-19(18-8-2-15(24(30)33)10-20(18)32)23(14-3-9-21-22(11-14)38-13-37-21)25(34)31-39(35,36)17-6-4-16(5-7-17)26(27,28)29/h2-12,23H,13H2,1H3,(H2,30,33)(H,31,34)	WYPXYGWFNRNTHH-UHFFFAOYSA-N	50108195	3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(4-trifluoromethyl-benzenesulfonylamino)-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL276982	Endothelin-1 receptor			 6.5							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108195&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458604	104003416		CHEMBL276982				ZINC28257273	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196013	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O	InChI=1S/C29H29N3O6S/c1-4-32-15-23(22-11-7-20(28(30)33)13-24(22)32)27(19-8-12-25-26(14-19)38-16-37-25)29(34)31-39(35,36)21-9-5-18(6-10-21)17(2)3/h5-15,17,27H,4,16H2,1-3H3,(H2,30,33)(H,31,34)	PYSZMARKHQLZJY-UHFFFAOYSA-N	50108196	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid amide::CHEMBL539420	Endothelin-1 receptor			 3.5							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108196&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738878	104003417		CHEMBL539420				ZINC28264165	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196017	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccc(cc12)C(=O)NC	InChI=1S/C30H31N3O6S/c1-5-33-16-24(23-12-8-21(14-25(23)33)29(34)31-4)28(20-9-13-26-27(15-20)39-17-38-26)30(35)32-40(36,37)22-10-6-19(7-11-22)18(2)3/h6-16,18,28H,5,17H2,1-4H3,(H,31,34)(H,32,35)	XJSUBSFOTRRUES-UHFFFAOYSA-N	50108198	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid methylamide::CHEMBL433221	Endothelin-1 receptor			 30							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108198&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738880	104003419		CHEMBL433221				ZINC28265038	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196019	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C#N)c1ccc2OCOc2c1	InChI=1S/C28H25N3O5S/c1-17(2)19-5-8-21(9-6-19)37(33,34)30-28(32)27(20-7-11-25-26(13-20)36-16-35-25)23-15-31(3)24-12-18(14-29)4-10-22(23)24/h4-13,15,17,27H,16H2,1-3H3,(H,30,32)	ODSGMLHBKUZJKR-UHFFFAOYSA-N	50108201	CHEMBL274758::N-[2-Benzo[1,3]dioxol-5-yl-2-(6-cyano-1-methyl-1H-indol-3-yl)-acetyl]-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 61							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108201&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467231	104003422		CHEMBL274758				ZINC13436355	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196020	COc1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C26H23N3O7S/c1-29-13-20(19-9-3-16(25(27)30)11-21(19)29)24(15-4-10-22-23(12-15)36-14-35-22)26(31)28-37(32,33)18-7-5-17(34-2)6-8-18/h3-13,24H,14H2,1-2H3,(H2,27,30)(H,28,31)	BSLISXSHQLGIIZ-UHFFFAOYSA-N	50108185	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL280379	Endothelin-1 receptor			 2.8							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108185&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458670	104003406		CHEMBL280379				ZINC13436400	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196023	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(CN)ccc12)c1ccc2OCOc2c1	InChI=1S/C28H29N3O5S/c1-17(2)19-5-8-21(9-6-19)37(33,34)30-28(32)27(20-7-11-25-26(13-20)36-16-35-25)23-15-31(3)24-12-18(14-29)4-10-22(23)24/h4-13,15,17,27H,14,16,29H2,1-3H3,(H,30,32)	JGAUQCSCABMOTB-UHFFFAOYSA-N	50108199	CHEMBL279703::N-[2-(6-Aminomethyl-1-methyl-1H-indol-3-yl)-2-benzo[1,3]dioxol-5-yl-acetyl]-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 38							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108199&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467229	104003420		CHEMBL279703				ZINC13436367	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196027	Cn1cc(C(C(=O)NS(=O)(=O)c2ccc(Cl)cc2)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O	InChI=1S/C25H20ClN3O6S/c1-29-12-19(18-8-2-15(24(27)30)10-20(18)29)23(14-3-9-21-22(11-14)35-13-34-21)25(31)28-36(32,33)17-6-4-16(26)5-7-17/h2-12,23H,13H2,1H3,(H2,27,30)(H,28,31)	UXILKFUTGKEPOU-UHFFFAOYSA-N	50108200	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-chloro-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL433619	Endothelin-1 receptor			 7.5							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108200&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458999	104003421		CHEMBL433619				ZINC28260817	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196028	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)-c1nn[nH]n1)c1ccc2OCOc2c1	InChI=1S/C28H26N6O5S/c1-16(2)17-4-8-20(9-5-17)40(36,37)31-28(35)26(18-7-11-24-25(13-18)39-15-38-24)22-14-34(3)23-12-19(6-10-21(22)23)27-29-32-33-30-27/h4-14,16,26H,15H2,1-3H3,(H,31,35)(H,29,30,32,33)	YZWRJRVDHDWEOE-UHFFFAOYSA-N	50108205	CHEMBL281378::N-{2-Benzo[1,3]dioxol-5-yl-2-[1-methyl-6-(1H-tetrazol-5-yl)-1H-indol-3-yl]-acetyl}-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 35							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108205&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467240	104003426		CHEMBL281378				ZINC28259124	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196030	Cc1ccccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C26H23N3O6S/c1-15-5-3-4-6-23(15)36(32,33)28-26(31)24(16-8-10-21-22(12-16)35-14-34-21)19-13-29(2)20-11-17(25(27)30)7-9-18(19)20/h3-13,24H,14H2,1-2H3,(H2,27,30)(H,28,31)	WKYQABAYTVWYQR-UHFFFAOYSA-N	50108203	3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-2-sulfonylamino)-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22249	Endothelin-1 receptor			 5.2							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108203&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458669	104003424		CHEMBL22249				ZINC13436407	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196031	COc1cc(OC)nc(O[C@H](C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C22H22N2O6/c1-27-17-14-18(28-2)24-21(23-17)30-19(20(25)26)22(29-3,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1	FEJVSJIALLTFRP-LJQANCHMSA-N	50108202	(S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL23261::Darusentan	Endothelin-1 receptor			 0.800000							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			177236	104003423		CHEMBL23261	DB04883	3508		ZINC03826221	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196032	COC(=O)c1ccc2c(cn(C)c2c1)C(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C29H28N2O7S/c1-17(2)18-5-9-21(10-6-18)39(34,35)30-28(32)27(19-8-12-25-26(14-19)38-16-37-25)23-15-31(3)24-13-20(29(33)36-4)7-11-22(23)24/h5-15,17,27H,16H2,1-4H3,(H,30,32)	JFZCDDNWAVSNEV-UHFFFAOYSA-N	50108206	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid methyl ester::CHEMBL281121	Endothelin-1 receptor			 100							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108206&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738890	104003427		CHEMBL281121				ZINC28258268	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196036	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(CO)ccc12)c1ccc2OCOc2c1	InChI=1S/C28H28N2O6S/c1-17(2)19-5-8-21(9-6-19)37(33,34)29-28(32)27(20-7-11-25-26(13-20)36-16-35-25)23-14-30(3)24-12-18(15-31)4-10-22(23)24/h4-14,17,27,31H,15-16H2,1-3H3,(H,29,32)	SCMXLDCMGHKGGU-UHFFFAOYSA-N	50108188	CHEMBL279947::N-[2-Benzo[1,3]dioxol-5-yl-2-(6-hydroxymethyl-1-methyl-1H-indol-3-yl)-acetyl]-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 19							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108188&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44458399	104003409		CHEMBL279947				ZINC13436347	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196037	Cn1cc(C(C(=O)NS(=O)(=O)c2ccccc2)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O	InChI=1S/C25H21N3O6S/c1-28-13-19(18-9-7-16(24(26)29)11-20(18)28)23(15-8-10-21-22(12-15)34-14-33-21)25(30)27-35(31,32)17-5-3-2-4-6-17/h2-13,23H,14H2,1H3,(H2,26,29)(H,27,30)	QYBAEPJHJXGPBW-UHFFFAOYSA-N	50108197	3-(2-Benzenesulfonylamino-1-benzo[1,3]dioxol-5-yl-2-oxo-ethyl)-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL24015	Endothelin-1 receptor			 12							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108197&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44459272	104003418		CHEMBL24015				ZINC13436383	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196039	Cc1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C26H23N3O6S/c1-15-3-7-18(8-4-15)36(32,33)28-26(31)24(16-6-10-22-23(12-16)35-14-34-22)20-13-29(2)21-11-17(25(27)30)5-9-19(20)21/h3-13,24H,14H2,1-2H3,(H2,27,30)(H,28,31)	PUMKVXYNDYQHJI-UHFFFAOYSA-N	50108194	3-[1-Benzo[1,3]dioxol-5-yl-2-oxo-2-(toluene-4-sulfonylamino)-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL278109	Endothelin-1 receptor			 1.8							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108194&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10029171	104003415		CHEMBL278109				ZINC13436392	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196042	CCOc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C28H27N3O7S/c1-4-36-24-11-16(2)5-10-25(24)39(34,35)30-28(33)26(17-7-9-22-23(13-17)38-15-37-22)20-14-31(3)21-12-18(27(29)32)6-8-19(20)21/h5-14,26H,4,15H2,1-3H3,(H2,29,32)(H,30,33)	UEHPBBFVUYURNP-UHFFFAOYSA-N	50108204	3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22513	Endothelin-1 receptor			 0.550000							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108204&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915510	104003425		CHEMBL22513				ZINC14141063	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50196045	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccc(cc12)C(O)=O	InChI=1S/C29H28N2O7S/c1-4-31-15-23(22-11-7-20(29(33)34)13-24(22)31)27(19-8-12-25-26(14-19)38-16-37-25)28(32)30-39(35,36)21-9-5-18(6-10-21)17(2)3/h5-15,17,27H,4,16H2,1-3H3,(H,30,32)(H,33,34)	GBDHMDQPXDYBRO-UHFFFAOYSA-N	50108207	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid::CHEMBL23833	Endothelin-1 receptor			 32							ChEMBL	10.1016/s0960-894x(01)00660-6	10.7270/Q2JH3KG6	11755336			Rawson, DJ; Dack, KN; Dickinson, RP; James, K	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108207&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738879	104003428		CHEMBL23833				ZINC28261367	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192878	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1cc2OCOc2c(OC)c1	InChI=1S/C30H48N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h15-16,22-23,27H,7-14,17-20H2,1-6H3,(H,34,35)/t22-,23+,27-/m1/s1	OAEWNSKRLBVVBV-QSEAXJEQSA-N	50066391	(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::CHEMBL111612	Endothelin-1 receptor			 0.49							ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066391&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915028	103961033		CHEMBL111612				ZINC04394021	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192885	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1cc2OCOc2c(OC)c1	InChI=1S/C30H48N2O6/c1-7-10-13-31(14-11-8-2)26(33)19-32-18-22(21-15-24(36-6)28-25(16-21)37-20-38-28)27(29(34)35)23(32)17-30(4,5)12-9-3/h15-16,22-23,27H,7-14,17-20H2,1-6H3,(H,34,35)/t22-,23+,27-/m1/s1	OAEWNSKRLBVVBV-QSEAXJEQSA-N	50066391	(2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::1-Dibutylcarbamoylmethyl-2-(2,2-dimethyl-pentyl)-4-(7-methoxy-benzo[1,3]dioxol-5-yl)-pyrrolidine-3-carboxylic acid::CHEMBL111612	Endothelin-1 receptor		 0.46								ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066391&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915028	103961033		CHEMBL111612				ZINC04394021	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192899	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(C)c(F)c1)C(O)=O)c1ccc2OCCc2c1	InChI=1S/C30H39FN2O4/c1-4-6-13-32(14-7-5-2)27(34)19-33-18-24(21-10-11-26-22(16-21)12-15-37-26)28(30(35)36)29(33)23-9-8-20(3)25(31)17-23/h8-11,16-17,24,28-29H,4-7,12-15,18-19H2,1-3H3,(H,35,36)/t24-,28-,29+/m1/s1	QEEBBVPPVYZDDG-USOMCTOXSA-N	50106407	1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-5-yl)-2-(3-fluoro-4-methyl-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL128818	Endothelin-1 receptor		 0.039								ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106407&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9936145	104001962		CHEMBL128818				ZINC03964494	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192913	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(CC)c(F)c1)C(O)=O)c1ccc2OCCOc2c1	InChI=1S/C31H41FN2O5/c1-4-7-13-33(14-8-5-2)28(35)20-34-19-24(22-11-12-26-27(18-22)39-16-15-38-26)29(31(36)37)30(34)23-10-9-21(6-3)25(32)17-23/h9-12,17-18,24,29-30H,4-8,13-16,19-20H2,1-3H3,(H,36,37)/t24-,29-,30+/m1/s1	NRDKXLWFPVYSKL-DQWNXYKBSA-N	50106410	1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-(4-ethyl-3-fluoro-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL128479	Endothelin-1 receptor			 0.87							ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106410&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11027946	104001965		CHEMBL128479				ZINC27320588	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192915	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(CC)c(F)c1)C(O)=O)c1ccc2OCCc2c1	InChI=1S/C31H41FN2O4/c1-4-7-14-33(15-8-5-2)28(35)20-34-19-25(22-11-12-27-23(17-22)13-16-38-27)29(31(36)37)30(34)24-10-9-21(6-3)26(32)18-24/h9-12,17-18,25,29-30H,4-8,13-16,19-20H2,1-3H3,(H,36,37)/t25-,29-,30+/m1/s1	SVAMJINLNAHCIL-RKJPZGCHSA-N	50106399	1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-5-yl)-2-(4-ethyl-3-fluoro-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL338754	Endothelin-1 receptor			 0.76							ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106399&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11827489	104001954		CHEMBL338754				ZINC27315535	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192918	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(C)c(F)c1)C(O)=O)c1ccc2OCCc2c1	InChI=1S/C30H39FN2O4/c1-4-6-13-32(14-7-5-2)27(34)19-33-18-24(21-10-11-26-22(16-21)12-15-37-26)28(30(35)36)29(33)23-9-8-20(3)25(31)17-23/h8-11,16-17,24,28-29H,4-7,12-15,18-19H2,1-3H3,(H,35,36)/t24-,28-,29+/m1/s1	QEEBBVPPVYZDDG-USOMCTOXSA-N	50106407	1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-5-yl)-2-(3-fluoro-4-methyl-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL128818	Endothelin-1 receptor			 0.180							ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106407&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9936145	104001962		CHEMBL128818				ZINC03964494	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50192923	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(C)c(F)c1)C(O)=O)c1ccc2OCCc2c1	InChI=1S/C30H39FN2O4/c1-4-6-13-32(14-7-5-2)27(34)19-33-18-24(21-10-11-26-22(16-21)12-15-37-26)28(30(35)36)29(33)23-9-8-20(3)25(31)17-23/h8-11,16-17,24,28-29H,4-7,12-15,18-19H2,1-3H3,(H,35,36)/t24-,28-,29+/m1/s1	QEEBBVPPVYZDDG-USOMCTOXSA-N	50106407	1-Dibutylcarbamoylmethyl-4-(2,3-dihydro-benzofuran-5-yl)-2-(3-fluoro-4-methyl-phenyl)-pyrrolidine-3-carboxylic acid::CHEMBL128818	Endothelin-1 receptor			 0.18							ChEMBL	10.1021/jm010237l	10.7270/Q2JS9PR2	11689084			Jae, HS; Winn, M; von Geldern, TW; Sorensen, BK; Chiou, WJ; Nguyen, B; Marsh, KC; Opgenorth, TJ	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106407&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9936145	104001962		CHEMBL128818				ZINC03964494	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50214252	CCCCC1CCN(CCCC(=O)c2ccccc2C)CC1	InChI=1S/C20H31NO/c1-3-4-9-18-12-15-21(16-13-18)14-7-11-20(22)19-10-6-5-8-17(19)2/h5-6,8,10,18H,3-4,7,9,11-16H2,1-2H3	ANTKBACNWQHQJE-UHFFFAOYSA-N	50326219	4-(4-butylpiperidin-1-yl)-1-o-tolylbutan-1-one::CHEMBL1242950::CHEMBL2206334	Endothelin-1 receptor		<1000								ChEMBL	10.1021/jm100697g	10.7270/Q2765G9K	20684563			Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326219&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9948320	123105334		CHEMBL2206334CHEMBL1242950		289		ZINC02022527	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216559	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(nc12)N1CCCC1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C27H26N2O5/c1-32-18-7-4-16(5-8-18)24-25(27(30)31)23(17-6-10-20-21(14-17)34-15-33-20)19-9-11-22(28-26(19)24)29-12-2-3-13-29/h4-11,14,23-25H,2-3,12-13,15H2,1H3,(H,30,31)/t23-,24-,25+/m0/s1	HAIMYEQNXQUSSG-CCDWMCETSA-N	50119659	(R)-5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-pyrrolidin-1-yl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL102173	Endothelin-1 receptor			 2.2							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119659&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334130	104012802		CHEMBL102173				ZINC13859865	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216561	CCCCCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C28H29NO5/c1-3-4-5-6-19-10-13-21-24(18-9-14-22-23(15-18)34-16-33-22)26(28(30)31)25(27(21)29-19)17-7-11-20(32-2)12-8-17/h7-15,24-26H,3-6,16H2,1-2H3,(H,30,31)/t24-,25-,26+/m0/s1	FHOLSLVTQPRBKJ-KKUQBAQOSA-N	50119661	5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-pentyl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL320208	Endothelin-1 receptor			 1.9							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119661&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334129	104012804		CHEMBL320208				ZINC13859852	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216564	CCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C25H23NO5/c1-3-16-7-10-18-21(15-6-11-19-20(12-15)31-13-30-19)23(25(27)28)22(24(18)26-16)14-4-8-17(29-2)9-5-14/h4-12,21-23H,3,13H2,1-2H3,(H,27,28)/t21-,22-,23+/m0/s1	XIIITWQEAPOZLF-RJGXRXQPSA-N	50119660	5-Benzo[1,3]dioxol-5-yl-2-ethyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL102773	Endothelin-1 receptor			 4.5							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119660&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333578	104012803		CHEMBL102773				ZINC13859849	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216566	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(nc12)C1CC1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C26H23NO5/c1-30-17-7-4-15(5-8-17)23-24(26(28)29)22(16-6-11-20-21(12-16)32-13-31-20)18-9-10-19(14-2-3-14)27-25(18)23/h4-12,14,22-24H,2-3,13H2,1H3,(H,28,29)/t22-,23-,24+/m0/s1	YZQQVZQBQWFHTP-KMDXXIMOSA-N	50119664	(R)-5-Benzo[1,3]dioxol-5-yl-2-but-3-enyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL430695	Endothelin-1 receptor			 1.6							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119664&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334065	104012807		CHEMBL430695				ZINC13859855	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216568	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(CCC=C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C27H25NO5/c1-3-4-5-18-9-12-20-23(17-8-13-21-22(14-17)33-15-32-21)25(27(29)30)24(26(20)28-18)16-6-10-19(31-2)11-7-16/h3,6-14,23-25H,1,4-5,15H2,2H3,(H,29,30)/t23-,24-,25+/m0/s1	XBXKAPLYGJALOL-CCDWMCETSA-N	50119665	5-Benzo[1,3]dioxol-5-yl-2-but-3-enyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL101424	Endothelin-1 receptor			 0.200000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119665&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334128	104012808		CHEMBL101424				ZINC13859854	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216569	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(nc12)N(C)C(C)C)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C27H28N2O5/c1-15(2)29(3)22-12-10-19-23(17-7-11-20-21(13-17)34-14-33-20)25(27(30)31)24(26(19)28-22)16-5-8-18(32-4)9-6-16/h5-13,15,23-25H,14H2,1-4H3,(H,30,31)/t23-,24-,25+/m0/s1	OYGNCRBWGRCEDM-CCDWMCETSA-N	50119667	(R)-5-Benzo[1,3]dioxol-5-yl-2-(isopropyl-methyl-amino)-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL103090	Endothelin-1 receptor			 3.2							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119667&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334145	104012810		CHEMBL103090				ZINC13859864	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216570	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C24H21NO5/c1-13-3-9-17-20(15-6-10-18-19(11-15)30-12-29-18)22(24(26)27)21(23(17)25-13)14-4-7-16(28-2)8-5-14/h3-11,20-22H,12H2,1-2H3,(H,26,27)/t20-,21-,22+/m0/s1	ACMPQUAKYNONQE-FDFHNCONSA-N	50119669	5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-methyl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL103001	Endothelin-1 receptor			 5.7							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119669&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333867	104012812		CHEMBL103001				ZINC13859848	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216572	CCCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H25NO5/c1-3-4-17-8-11-19-22(16-7-12-20-21(13-16)32-14-31-20)24(26(28)29)23(25(19)27-17)15-5-9-18(30-2)10-6-15/h5-13,22-24H,3-4,14H2,1-2H3,(H,28,29)/t22-,23-,24+/m0/s1	JMCMZOQWXJPCLI-KMDXXIMOSA-N	50119670	5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-propyl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL105591	Endothelin-1 receptor			 0.370000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119670&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333913	104012813		CHEMBL105591				ZINC13859850	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216574	CCCCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H27NO5/c1-3-4-5-18-9-12-20-23(17-8-13-21-22(14-17)33-15-32-21)25(27(29)30)24(26(20)28-18)16-6-10-19(31-2)11-7-16/h6-14,23-25H,3-5,15H2,1-2H3,(H,29,30)/t23-,24-,25+/m0/s1	AQEWYBHXBBBFNY-CCDWMCETSA-N	50119671	5-Benzo[1,3]dioxol-5-yl-2-butyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL102969	Endothelin-1 receptor			 0.210000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119671&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10321290	104012814		CHEMBL102969				ZINC13859851	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216576	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2cccnc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C23H19NO5/c1-27-15-7-4-13(5-8-15)20-21(23(25)26)19(16-3-2-10-24-22(16)20)14-6-9-17-18(11-14)29-12-28-17/h2-11,19-21H,12H2,1H3,(H,25,26)/t19-,20-,21+/m0/s1	AIJJGHXRGHAKEG-PCCBWWKXSA-N	50119672	(5S,7R)-5-(1,3-benzodioxol-5-yl)-7-(4-methoxyphenyl)-6,7-dihydro-5H-cyclopenta[b]pyridine-6-carboxylic acid::CHEMBL102825	Endothelin-1 receptor			 2.4							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119672&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9821701	104012815		CHEMBL102825				ZINC13837899	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216577	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(CC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C27H27NO5/c1-15(2)12-18-7-10-20-23(17-6-11-21-22(13-17)33-14-32-21)25(27(29)30)24(26(20)28-18)16-4-8-19(31-3)9-5-16/h4-11,13,15,23-25H,12,14H2,1-3H3,(H,29,30)/t23-,24-,25+/m0/s1	BFGUYLRYXCFHGG-CCDWMCETSA-N	50119663	5-Benzo[1,3]dioxol-5-yl-2-isobutyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL102314	Endothelin-1 receptor			 0.320000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119663&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334150	104012806		CHEMBL102314				ZINC13859853	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216580	CCCOc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H25NO6/c1-3-12-31-21-11-9-18-22(16-6-10-19-20(13-16)33-14-32-19)24(26(28)29)23(25(18)27-21)15-4-7-17(30-2)8-5-15/h4-11,13,22-24H,3,12,14H2,1-2H3,(H,28,29)/t22-,23-,24+/m0/s1	DTXFUEYWZXGNEF-KMDXXIMOSA-N	50119674	(R)-5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-propoxy-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL321520	Endothelin-1 receptor			 0.920000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119674&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333598	104012817		CHEMBL321520				ZINC13859860	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216581	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(CCCO)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C26H25NO6/c1-31-18-8-4-15(5-9-18)23-24(26(29)30)22(16-6-11-20-21(13-16)33-14-32-20)19-10-7-17(3-2-12-28)27-25(19)23/h4-11,13,22-24,28H,2-3,12,14H2,1H3,(H,29,30)/t22-,23-,24+/m0/s1	JOMWRKGBRATICM-KMDXXIMOSA-N	50119662	(R)-5-Benzo[1,3]dioxol-5-yl-2-(3-hydroxy-propyl)-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL323561	Endothelin-1 receptor			 0.550000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119662&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334097	104012805		CHEMBL323561				ZINC13859857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216582	CCCNc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H26N2O5/c1-3-12-27-21-11-9-18-22(16-6-10-19-20(13-16)33-14-32-19)24(26(29)30)23(25(18)28-21)15-4-7-17(31-2)8-5-15/h4-11,13,22-24H,3,12,14H2,1-2H3,(H,27,28)(H,29,30)/t22-,23-,24+/m0/s1	YGGFLIPTDYLEIC-KMDXXIMOSA-N	50119676	(R)-5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-propylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL432012	Endothelin-1 receptor			 0.120000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119676&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334146	104012819		CHEMBL432012				ZINC03979518	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216583	CCNCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H26N2O5/c1-3-27-13-17-7-10-19-22(16-6-11-20-21(12-16)33-14-32-20)24(26(29)30)23(25(19)28-17)15-4-8-18(31-2)9-5-15/h4-12,22-24,27H,3,13-14H2,1-2H3,(H,29,30)/t22-,23-,24+/m0/s1	VTCDHOQFPYTIFV-KMDXXIMOSA-N	50119675	(R)-5-Benzo[1,3]dioxol-5-yl-2-ethylaminomethyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL320631	Endothelin-1 receptor			 7							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119675&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333887	104012818		CHEMBL320631				ZINC13859862	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216586	CCOCc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H25NO6/c1-3-31-13-17-7-10-19-22(16-6-11-20-21(12-16)33-14-32-20)24(26(28)29)23(25(19)27-17)15-4-8-18(30-2)9-5-15/h4-12,22-24H,3,13-14H2,1-2H3,(H,28,29)/t22-,23-,24+/m0/s1	ILKUULNNGMUWFG-KMDXXIMOSA-N	50119673	(R)-5-Benzo[1,3]dioxol-5-yl-2-ethoxymethyl-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL430506	Endothelin-1 receptor			 0.510000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119673&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333721	104012816		CHEMBL430506				ZINC13859859	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216591	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(nc12)-c1ccccc1)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H23NO5/c1-33-20-10-7-18(8-11-20)26-27(29(31)32)25(19-9-14-23-24(15-19)35-16-34-23)21-12-13-22(30-28(21)26)17-5-3-2-4-6-17/h2-15,25-27H,16H2,1H3,(H,31,32)/t25-,26-,27+/m0/s1	UIYNSXMUJGBENK-GMQQYTKMSA-N	50119666	(R)-5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-phenyl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL102411	Endothelin-1 receptor			 15							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119666&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334053	104012809		CHEMBL102411				ZINC13859856	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216595	CCCSc1ccc2[C@@H]([C@H]([C@@H](c2n1)c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C26H25NO5S/c1-3-12-33-21-11-9-18-22(16-6-10-19-20(13-16)32-14-31-19)24(26(28)29)23(25(18)27-21)15-4-7-17(30-2)8-5-15/h4-11,13,22-24H,3,12,14H2,1-2H3,(H,28,29)/t22-,23-,24+/m0/s1	CQHSRRONBVIJRO-KMDXXIMOSA-N	50119668	(R)-5-Benzo[1,3]dioxol-5-yl-7-(4-methoxy-phenyl)-2-propylsulfanyl-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL105494	Endothelin-1 receptor			 8.2							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119668&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333889	104012811		CHEMBL105494				ZINC13859861	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216596	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(CCC(O)=O)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C26H23NO7/c1-32-17-7-2-14(3-8-17)23-24(26(30)31)22(15-4-10-19-20(12-15)34-13-33-19)18-9-5-16(27-25(18)23)6-11-21(28)29/h2-5,7-10,12,22-24H,6,11,13H2,1H3,(H,28,29)(H,30,31)/t22-,23-,24+/m0/s1	QZLAMPMKCJHEKL-KMDXXIMOSA-N	50119677	(R)-5-Benzo[1,3]dioxol-5-yl-2-(2-carboxy-ethyl)-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL322434	Endothelin-1 receptor			 150							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119677&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44334084	104012820		CHEMBL322434				ZINC13859858	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50216598	COc1ccc(cc1)[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C26H26N2O5/c1-14(2)27-21-11-9-18-22(16-6-10-19-20(12-16)33-13-32-19)24(26(29)30)23(25(18)28-21)15-4-7-17(31-3)8-5-15/h4-12,14,22-24H,13H2,1-3H3,(H,27,28)(H,29,30)/t22-,23-,24+/m0/s1	WQULYHKGCLHTBZ-KMDXXIMOSA-N	50119678	(R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamino-7-(4-methoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL448165	Endothelin-1 receptor			 0.100000							ChEMBL	10.1016/s0960-894x(02)00663-7	10.7270/Q2KK9B3N	12372497			Niiyama, K; Takahashi, H; Nagase, T; Kojima, H; Amano, Y; Katsuki, K; Yamakawa, T; Ozaki, S; Ihara, M; Yano, M; Fukuroda, T; Nishikibe, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119678&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10366278	104012821		CHEMBL448165				ZINC13859863	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225462	CCCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)-c1cc(OC)c(OC)c(OC)c1	InChI=1S/C33H41N5O10S2/c1-8-17-49(39,40)35-15-16-47-33-30(48-25-12-10-9-11-24(25)43-4)32(38-50(41,42)28-14-13-22(20-34-28)21(2)3)36-31(37-33)23-18-26(44-5)29(46-7)27(19-23)45-6/h9-14,18-21,35H,8,15-17H2,1-7H3,(H,36,37,38)	KWLKTEPEDKFNSG-UHFFFAOYSA-N	50124418	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide::CHEMBL176997	Endothelin-1 receptor			 261							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124418&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9810571	104016733		CHEMBL176997				ZINC03934529	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225464	CCCS(=O)(=O)NCCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)C1CC1	InChI=1S/C28H37N5O7S2/c1-5-17-41(34,35)30-15-8-16-39-28-25(40-23-10-7-6-9-22(23)38-4)27(31-26(32-28)20-11-12-20)33-42(36,37)24-14-13-21(18-29-24)19(2)3/h6-7,9-10,13-14,18-20,30H,5,8,11-12,15-17H2,1-4H3,(H,31,32,33)	HQIPFADRUMZDIT-UHFFFAOYSA-N	50124420	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(propane-1-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide::CHEMBL177538	Endothelin-1 receptor			 82							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124420&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9917072	104016735		CHEMBL177538				ZINC28101363	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225465	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)-c1ccncc1	InChI=1S/C31H30N6O7S2/c1-21-8-11-24(12-9-21)45(38,39)34-18-19-43-31-28(44-26-7-5-4-6-25(26)42-3)30(35-29(36-31)23-14-16-32-17-15-23)37-46(40,41)27-13-10-22(2)20-33-27/h4-17,20,34H,18-19H2,1-3H3,(H,35,36,37)	NIUISTMMHSJGFT-UHFFFAOYSA-N	50124422	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-pyridin-4-yl-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL366628	Endothelin-1 receptor			 2193							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124422&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184249	104016737		CHEMBL366628				ZINC28018518	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225466	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)-c1ncccn1	InChI=1S/C34H36N6O7S2/c1-23-11-15-25(16-12-23)48(41,42)37-21-22-46-33-29(47-28-10-7-6-9-27(28)45-5)30(38-32(39-33)31-35-19-8-20-36-31)40-49(43,44)26-17-13-24(14-18-26)34(2,3)4/h6-20,37H,21-22H2,1-5H3,(H,38,39,40)	YAEHNRUZTLQGFP-UHFFFAOYSA-N	50124423	4-[4-(tert-butyl)phenylsulfonamido]-5-(2-methoxyphenoxy)-6-[2-(4-methylphenylsulfonamido)ethoxy]-2-(2-pyrimidinyl)pyrimidine::CHEMBL172441	Endothelin-1 receptor			 8390							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124423&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44386069	104016738		CHEMBL172441				ZINC28019818	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225468	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)C1CC1	InChI=1S/C31H35N5O7S2/c1-20(2)23-13-16-27(32-19-23)45(39,40)36-30-28(43-26-8-6-5-7-25(26)41-4)31(35-29(34-30)22-11-12-22)42-18-17-33-44(37,38)24-14-9-21(3)10-15-24/h5-10,13-16,19-20,22,33H,11-12,17-18H2,1-4H3,(H,34,35,36)	OJVKLWQZUMZBLD-UHFFFAOYSA-N	50124421	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL175268	Endothelin-1 receptor			 1050							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124421&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874379	104016736		CHEMBL175268				ZINC28086362	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225469	CCCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC)C1CC1	InChI=1S/C25H31N5O7S2/c1-4-15-38(31,32)27-13-14-36-25-22(37-20-8-6-5-7-19(20)35-3)24(28-23(29-25)18-10-11-18)30-39(33,34)21-12-9-17(2)16-26-21/h5-9,12,16,18,27H,4,10-11,13-15H2,1-3H3,(H,28,29,30)	JTNMQFVZMZRTQJ-UHFFFAOYSA-N	50124425	5-Methyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL174781	Endothelin-1 receptor			 1320							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124425&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44386163	104016740		CHEMBL174781				ZINC28099315	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225471	CCS(=O)(=O)NCCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)C1CC1	InChI=1S/C27H35N5O7S2/c1-5-40(33,34)29-15-8-16-38-27-24(39-22-10-7-6-9-21(22)37-4)26(30-25(31-27)19-11-12-19)32-41(35,36)23-14-13-20(17-28-23)18(2)3/h6-7,9-10,13-14,17-19,29H,5,8,11-12,15-16H2,1-4H3,(H,30,31,32)	UPQGVXBBBKNPNZ-UHFFFAOYSA-N	50124427	5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide::CHEMBL177802	Endothelin-1 receptor			 45							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124427&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184234	104016742		CHEMBL177802				ZINC28105950	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225474	CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)C1CC1	InChI=1S/C28H36N4O7S2/c1-6-40(33,34)29-17-18-38-27-24(39-23-10-8-7-9-22(23)37-5)26(30-25(31-27)19-11-12-19)32-41(35,36)21-15-13-20(14-16-21)28(2,3)4/h7-10,13-16,19,29H,6,11-12,17-18H2,1-5H3,(H,30,31,32)	CHLXSJALJVYDID-UHFFFAOYSA-N	50124430	4-tert-Butyl-N-[2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL176749	Endothelin-1 receptor			 119							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124430&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184228	104016745		CHEMBL176749				ZINC28090196	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225480	CCS(=O)(=O)NCCCOc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C30H36N6O7S2/c1-6-44(37,38)33-19-10-20-42-29-25(43-24-12-8-7-11-23(24)41-5)26(34-28(35-29)27-31-17-9-18-32-27)36-45(39,40)22-15-13-21(14-16-22)30(2,3)4/h7-9,11-18,33H,6,10,19-20H2,1-5H3,(H,34,35,36)	ZFISXVCGLSYRRJ-UHFFFAOYSA-N	50124434	4-tert-Butyl-N-[6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL366872	Endothelin-1 receptor			 1591							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124434&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9852624	104016749		CHEMBL366872				ZINC28017255	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225481	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)C1CC1	InChI=1S/C33H38N4O7S2/c1-22-10-16-25(17-11-22)45(38,39)34-20-21-43-32-29(44-28-9-7-6-8-27(28)42-5)31(35-30(36-32)23-12-13-23)37-46(40,41)26-18-14-24(15-19-26)33(2,3)4/h6-11,14-19,23,34H,12-13,20-21H2,1-5H3,(H,35,36,37)	YIAMEKMEHNLSQG-UHFFFAOYSA-N	50124424	4-[4-(tert-butyl)phenylsulfonamido]-2-cyclopropyl-5-(2-methoxyphenoxy)-6-[2-(4-methylphenylsulfonamido)ethoxy]pyrimidine::CHEMBL176418	Endothelin-1 receptor			 4900							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124424&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385523	104016739		CHEMBL176418				ZINC28019368	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225484	CCCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)C1CC1	InChI=1S/C27H35N5O7S2/c1-5-16-40(33,34)29-14-15-38-27-24(39-22-9-7-6-8-21(22)37-4)26(30-25(31-27)19-10-11-19)32-41(35,36)23-13-12-20(17-28-23)18(2)3/h6-9,12-13,17-19,29H,5,10-11,14-16H2,1-4H3,(H,30,31,32)	LYOPDHNZJQBGAC-UHFFFAOYSA-N	50124440	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL171950	Endothelin-1 receptor			 80							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124440&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184229	104016755		CHEMBL171950				ZINC28021439	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225486	CCS(=O)(=O)NCCCOc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)C1CC1	InChI=1S/C29H38N4O7S2/c1-6-41(34,35)30-18-9-19-39-28-25(40-24-11-8-7-10-23(24)38-5)27(31-26(32-28)20-12-13-20)33-42(36,37)22-16-14-21(15-17-22)29(2,3)4/h7-8,10-11,14-17,20,30H,6,9,12-13,18-19H2,1-5H3,(H,31,32,33)	GWVRRZASHHOARI-UHFFFAOYSA-N	50124438	4-tert-Butyl-N-[2-cyclopropyl-6-(3-ethanesulfonylamino-propoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL368617	Endothelin-1 receptor			 48							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124438&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9830495	104016753		CHEMBL368617				ZINC28087576	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225487	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCCNS(=O)(=O)c1ccc(C)cc1)N1CCOCC1	InChI=1S/C33H40N6O8S2/c1-23(2)25-12-15-29(34-22-25)49(42,43)38-31-30(47-28-9-6-5-8-27(28)44-4)32(37-33(36-31)39-17-20-45-21-18-39)46-19-7-16-35-48(40,41)26-13-10-24(3)11-14-26/h5-6,8-15,22-23,35H,7,16-21H2,1-4H3,(H,36,37,38)	VKZGOHFGTOOZHY-UHFFFAOYSA-N	50124439	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[3-(toluene-4-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide::CHEMBL368107	Endothelin-1 receptor			 116							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124439&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184194	104016754		CHEMBL368107				ZINC28019891	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225489	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCCNS(=O)(=O)c1cccs1)-c1ncccn1	InChI=1S/C32H34N6O7S3/c1-32(2,3)22-13-15-23(16-14-22)47(39,40)38-28-27(45-25-11-6-5-10-24(25)43-4)31(37-30(36-28)29-33-17-8-18-34-29)44-20-9-19-35-48(41,42)26-12-7-21-46-26/h5-8,10-18,21,35H,9,19-20H2,1-4H3,(H,36,37,38)	HDWHUKBOFNHSSO-UHFFFAOYSA-N	50124442	CHEMBL276949::Thiophene-2-sulfonic acid {3-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-propyl}-amide	Endothelin-1 receptor			 86							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124442&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9810400	104016757		CHEMBL276949				ZINC28021444	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225490	CCCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)N1CCOCC1	InChI=1S/C28H38N6O8S2/c1-5-18-43(35,36)30-12-15-41-27-25(42-23-9-7-6-8-22(23)39-4)26(31-28(32-27)34-13-16-40-17-14-34)33-44(37,38)24-11-10-21(19-29-24)20(2)3/h6-11,19-20,30H,5,12-18H2,1-4H3,(H,31,32,33)	RQNOIZBVICJIJP-UHFFFAOYSA-N	50124441	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL369676	Endothelin-1 receptor			 140							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124441&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9961131	104016756		CHEMBL369676				ZINC28018631	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225492	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCNS(=O)(=O)c1cccs1)-c1cc(OC)c(OC)c(OC)c1	InChI=1S/C34H37N5O10S3/c1-21(2)22-13-14-28(35-20-22)51(40,41)39-33-31(49-25-11-8-7-10-24(25)44-3)34(48-16-15-36-52(42,43)29-12-9-17-50-29)38-32(37-33)23-18-26(45-4)30(47-6)27(19-23)46-5/h7-14,17-21,36H,15-16H2,1-6H3,(H,37,38,39)	XOQAUJRUGUVSMZ-UHFFFAOYSA-N	50124443	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide::CHEMBL277275	Endothelin-1 receptor			 1317							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124443	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124443&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9853680	104016758		CHEMBL277275				ZINC95608210	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225494	CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C29H34N6O7S2/c1-6-43(36,37)32-18-19-41-28-24(42-23-11-8-7-10-22(23)40-5)25(33-27(34-28)26-30-16-9-17-31-26)35-44(38,39)21-14-12-20(13-15-21)29(2,3)4/h7-17,32H,6,18-19H2,1-5H3,(H,33,34,35)	JXZLHWXGEORAOB-UHFFFAOYSA-N	50124435	4-tert-Butyl-N-[6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL172029	Endothelin-1 receptor			 487							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385522	104016750		CHEMBL172029				ZINC28018984	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225495	CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC)-c1ccncc1	InChI=1S/C26H28N6O7S2/c1-4-40(33,34)29-15-16-38-26-23(39-21-8-6-5-7-20(21)37-3)25(30-24(31-26)19-11-13-27-14-12-19)32-41(35,36)22-10-9-18(2)17-28-22/h5-14,17,29H,4,15-16H2,1-3H3,(H,30,31,32)	KPQBEJDBDRNENR-UHFFFAOYSA-N	50124445	5-Methyl-pyridine-2-sulfonic acid [6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide::CHEMBL174413	Endothelin-1 receptor			 185							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124445&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184206	104016760		CHEMBL174413				ZINC28008404	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225498	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCNS(=O)(=O)c1cccs1)-c1ccncc1	InChI=1S/C28H26N6O7S3/c1-19-9-10-23(30-18-19)43(35,36)34-27-25(41-22-7-4-3-6-21(22)39-2)28(33-26(32-27)20-11-13-29-14-12-20)40-16-15-31-44(37,38)24-8-5-17-42-24/h3-14,17-18,31H,15-16H2,1-2H3,(H,32,33,34)	VICZNPBUMWESDN-UHFFFAOYSA-N	50124447	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-pyridin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL367017	Endothelin-1 receptor			 2838							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124447&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184179	104016762		CHEMBL367017				ZINC28016653	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225499	CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)C1CC1	InChI=1S/C26H33N5O7S2/c1-5-39(32,33)28-14-15-37-26-23(38-21-9-7-6-8-20(21)36-4)25(29-24(30-26)18-10-11-18)31-40(34,35)22-13-12-19(16-27-22)17(2)3/h6-9,12-13,16-18,28H,5,10-11,14-15H2,1-4H3,(H,29,30,31)	GWBCKOWLDKFIHO-UHFFFAOYSA-N	50124428	5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide::CHEMBL172071	Endothelin-1 receptor			 50							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124428&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9873255	104016743		CHEMBL172071				ZINC28015282	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225501	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)N1CCOCC1	InChI=1S/C32H38N6O8S2/c1-22(2)24-11-14-28(33-21-24)48(41,42)37-30-29(46-27-8-6-5-7-26(27)43-4)31(36-32(35-30)38-16-19-44-20-17-38)45-18-15-34-47(39,40)25-12-9-23(3)10-13-25/h5-14,21-22,34H,15-20H2,1-4H3,(H,35,36,37)	YCRCGPMIFXVQLZ-UHFFFAOYSA-N	50124444	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(toluene-4-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL367274	Endothelin-1 receptor			 1385							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124444&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9831527	104016759		CHEMBL367274				ZINC28088499	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225505	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCCNS(=O)(=O)c1cccs1)C1CC1	InChI=1S/C29H33N5O7S3/c1-19(2)21-13-14-24(30-18-21)43(35,36)34-28-26(41-23-9-5-4-8-22(23)39-3)29(33-27(32-28)20-11-12-20)40-16-7-15-31-44(37,38)25-10-6-17-42-25/h4-6,8-10,13-14,17-20,31H,7,11-12,15-16H2,1-3H3,(H,32,33,34)	AEDJOIBTFWFFLB-UHFFFAOYSA-N	50124446	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(thiophene-2-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide::CHEMBL367444	Endothelin-1 receptor			 22							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124446&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9917706	104016761		CHEMBL367444				ZINC28019057	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225506	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCCNS(=O)(=O)c1ccc(C)cc1)C1CC1	InChI=1S/C32H37N5O7S2/c1-21(2)24-14-17-28(33-20-24)46(40,41)37-31-29(44-27-9-6-5-8-26(27)42-4)32(36-30(35-31)23-12-13-23)43-19-7-18-34-45(38,39)25-15-10-22(3)11-16-25/h5-6,8-11,14-17,20-21,23,34H,7,12-13,18-19H2,1-4H3,(H,35,36,37)	YLMSOIIFAYJNMX-UHFFFAOYSA-N	50124432	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(toluene-4-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide::CHEMBL367443	Endothelin-1 receptor			 77							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124432&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9874557	104016747		CHEMBL367443				ZINC28019052	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225510	CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC)C1CC1	InChI=1S/C24H29N5O7S2/c1-4-37(30,31)26-13-14-35-24-21(36-19-8-6-5-7-18(19)34-3)23(27-22(28-24)17-10-11-17)29-38(32,33)20-12-9-16(2)15-25-20/h5-9,12,15,17,26H,4,10-11,13-14H2,1-3H3,(H,27,28,29)	VKVKIDBOTDIUCJ-UHFFFAOYSA-N	50124437	5-Methyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide::CHEMBL368528	Endothelin-1 receptor			 582							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124437&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384723	104016752		CHEMBL368528				ZINC28013477	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225512	CCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)N1CCOCC1	InChI=1S/C27H36N6O8S2/c1-5-42(34,35)29-12-15-40-26-24(41-22-9-7-6-8-21(22)38-4)25(30-27(31-26)33-13-16-39-17-14-33)32-43(36,37)23-11-10-20(18-28-23)19(2)3/h6-11,18-19,29H,5,12-17H2,1-4H3,(H,30,31,32)	DNIIBGYNGASUDE-UHFFFAOYSA-N	50124431	5-Isopropyl-pyridine-2-sulfonic acid [6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide::CHEMBL367958	Endothelin-1 receptor			 19							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124431&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9830773	104016746		CHEMBL367958				ZINC28020781	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225514	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCCNS(=O)(=O)c1cccs1)C1CC1	InChI=1S/C31H36N4O7S3/c1-31(2,3)22-14-16-23(17-15-22)44(36,37)35-29-27(42-25-10-6-5-9-24(25)40-4)30(34-28(33-29)21-12-13-21)41-19-8-18-32-45(38,39)26-11-7-20-43-26/h5-7,9-11,14-17,20-21,32H,8,12-13,18-19H2,1-4H3,(H,33,34,35)	BCRJIIJVFJJYRD-UHFFFAOYSA-N	50124419	CHEMBL172297::Thiophene-2-sulfonic acid {3-[6-(4-tert-butyl-benzenesulfonylamino)-2-cyclopropyl-5-(2-methoxy-phenoxy)-pyrimidin-4-yloxy]-propyl}-amide	Endothelin-1 receptor			 14							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124419&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9831249	104016734		CHEMBL172297				ZINC03980440	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225516	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCNS(=O)(=O)c1cccs1)-c1ncccn1	InChI=1S/C31H32N6O7S3/c1-31(2,3)21-12-14-22(15-13-21)46(38,39)37-27-26(44-24-10-6-5-9-23(24)42-4)30(36-29(35-27)28-32-16-8-17-33-28)43-19-18-34-47(40,41)25-11-7-20-45-25/h5-17,20,34H,18-19H2,1-4H3,(H,35,36,37)	ASUNSLBCCFVKJD-UHFFFAOYSA-N	50124429	CHEMBL172030::Thiophene-2-sulfonic acid {2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-ethyl}-amide	Endothelin-1 receptor			 64							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124429&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9853077	104016744		CHEMBL172030				ZINC28018989	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225517	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCNS(=O)(=O)c1ccc(C)cc1)-c1cc(OC)c(OC)c(OC)c1	InChI=1S/C37H41N5O10S2/c1-23(2)25-14-17-32(38-22-25)54(45,46)42-36-34(52-29-11-9-8-10-28(29)47-4)37(51-19-18-39-53(43,44)27-15-12-24(3)13-16-27)41-35(40-36)26-20-30(48-5)33(50-7)31(21-26)49-6/h8-17,20-23,39H,18-19H2,1-7H3,(H,40,41,42)	PKQIJKCKDMECHH-UHFFFAOYSA-N	50124449	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(toluene-4-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide::CHEMBL173201	Endothelin-1 receptor			 5115.0							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124449	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124449&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9897092	104016764		CHEMBL173201				ZINC95606345	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225519	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCNS(=O)(=O)c1cccs1)-c1cc(OC)c(OC)c(OC)c1	InChI=1S/C32H33N5O10S3/c1-20-12-13-26(33-19-20)49(38,39)37-31-29(47-23-10-7-6-9-22(23)42-2)32(46-15-14-34-50(40,41)27-11-8-16-48-27)36-30(35-31)21-17-24(43-3)28(45-5)25(18-21)44-4/h6-13,16-19,34H,14-15H2,1-5H3,(H,35,36,37)	GBJIVPGNFQWBRC-UHFFFAOYSA-N	50124436	5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-2-(3,4,5-trimethoxy-phenyl)-pyrimidin-4-yl]-amide::CHEMBL366627	Endothelin-1 receptor			 2770							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124436&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384610	104016751		CHEMBL366627				ZINC95538101	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225521	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(Cc2ccc3OCOc3c2)nc1OCCNS(=O)(=O)c1cccs1	InChI=1S/C31H29N5O9S3/c1-20-9-12-27(32-18-20)47(37,38)36-30-29(45-24-7-4-3-6-22(24)41-2)31(42-14-13-33-48(39,40)28-8-5-15-46-28)35-26(34-30)17-21-10-11-23-25(16-21)44-19-43-23/h3-12,15-16,18,33H,13-14,17,19H2,1-2H3,(H,34,35,36)	AREIPMZPPUMZCQ-UHFFFAOYSA-N	50124450	5-Methyl-pyridine-2-sulfonic acid {2-benzo[1,3]dioxol-5-ylmethyl-5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL368945	Endothelin-1 receptor			 2190							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124450&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385412	104016765		CHEMBL368945				ZINC28089969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225522	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCNS(=O)(=O)c1cccs1)C1CC1	InChI=1S/C26H27N5O7S3/c1-17-9-12-21(27-16-17)40(32,33)31-25-23(38-20-7-4-3-6-19(20)36-2)26(30-24(29-25)18-10-11-18)37-14-13-28-41(34,35)22-8-5-15-39-22/h3-9,12,15-16,18,28H,10-11,13-14H2,1-2H3,(H,29,30,31)	DVFAKRYNGZKIPA-UHFFFAOYSA-N	50124426	5-Methyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL174547	Endothelin-1 receptor			 1850							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124426&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385792	104016741		CHEMBL174547				ZINC28087609	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225523	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCNS(=O)(=O)c1cccs1)N1CCOCC1	InChI=1S/C27H30N6O8S3/c1-19-9-10-22(28-18-19)43(34,35)32-25-24(41-21-7-4-3-6-20(21)38-2)26(31-27(30-25)33-12-15-39-16-13-33)40-14-11-29-44(36,37)23-8-5-17-42-23/h3-10,17-18,29H,11-16H2,1-2H3,(H,30,31,32)	JGEXEIBPRHWMSL-UHFFFAOYSA-N	50124433	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL367275	Endothelin-1 receptor			 724							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124433&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18184256	104016748		CHEMBL367275				ZINC28088505	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225525	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCNS(=O)(=O)c1cccs1)N1CCOCC1	InChI=1S/C29H34N6O8S3/c1-20(2)21-10-11-24(30-19-21)45(36,37)34-27-26(43-23-8-5-4-7-22(23)40-3)28(33-29(32-27)35-13-16-41-17-14-35)42-15-12-31-46(38,39)25-9-6-18-44-25/h4-11,18-20,31H,12-17H2,1-3H3,(H,32,33,34)	DIAOYWORMSQRFB-UHFFFAOYSA-N	50124451	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(thiophene-2-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL172759	Endothelin-1 receptor			 587							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124451	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124451&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9853025	104016766		CHEMBL172759				ZINC28008782	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225529	CCCS(=O)(=O)NCCOc1nc(nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC)N1CCOCC1	InChI=1S/C26H34N6O8S2/c1-4-17-41(33,34)28-11-14-39-25-23(40-21-8-6-5-7-20(21)37-3)24(29-26(30-25)32-12-15-38-16-13-32)31-42(35,36)22-10-9-19(2)18-27-22/h5-10,18,28H,4,11-17H2,1-3H3,(H,29,30,31)	KZOKREKJZZEWAD-UHFFFAOYSA-N	50124448	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-[2-(propane-1-sulfonylamino)-ethoxy]-pyrimidin-4-yl}-amide::CHEMBL368738	Endothelin-1 receptor			 51							ChEMBL	10.1016/s0960-894x(02)01083-1	10.7270/Q2D50M9J	12617928			Boss, C; Bolli, MH; Weller, T; Fischli, W; Clozel, M	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124448&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9809270	104016763		CHEMBL368738				ZINC28089962	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225530	CCCCNC(=O)OCC#CCOc1nc(nc(NS(=O)(=O)c2ccc(C)cn2)c1Oc1ccccc1OC)N1CCOCC1	InChI=1S/C30H36N6O8S/c1-4-5-14-31-30(37)43-18-9-8-17-42-28-26(44-24-11-7-6-10-23(24)40-3)27(33-29(34-28)36-15-19-41-20-16-36)35-45(38,39)25-13-12-22(2)21-32-25/h6-7,10-13,21H,4-5,14-20H2,1-3H3,(H,31,37)(H,33,34,35)	IBNKZYKCCCSKLB-UHFFFAOYSA-N	50124452	Butyl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester::CHEMBL368989	Endothelin-1 receptor			 196							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124452&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10211543	104016767		CHEMBL368989				ZINC28023107	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225531	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)Nc1cnccn1)N1CCOCC1	InChI=1S/C30H30N8O8S/c1-21-9-10-25(33-19-21)47(40,41)37-27-26(46-23-8-4-3-7-22(23)42-2)28(36-29(35-27)38-13-17-43-18-14-38)44-15-5-6-16-45-30(39)34-24-20-31-11-12-32-24/h3-4,7-12,19-20H,13-18H2,1-2H3,(H,32,34,39)(H,35,36,37)	SQHRONMOLLICCQ-UHFFFAOYSA-N	50124453	CHEMBL175058::Pyrazin-2-yl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 2							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124453&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10146377	104016768		CHEMBL175058				ZINC28091941	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225532	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1ccnc(c1)-c1nc(=O)o[nH]1	InChI=1S/C31H28N6O7S/c1-6-17-42-29-25(43-24-10-8-7-9-23(24)41-5)28(37-45(39,40)21-13-11-20(12-14-21)31(2,3)4)33-26(34-29)19-15-16-32-22(18-19)27-35-30(38)44-36-27/h1,7-16,18H,17H2,2-5H3,(H,33,34,37)(H,35,36,38)	BYCLKBXHEZQIHD-UHFFFAOYSA-N	50124454	4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-benzenesulfonamide::CHEMBL368117	Endothelin-1 receptor			 66							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124454&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384952	104016769		CHEMBL368117				ZINC28088272	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225535	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCO)-c1ncccn1	InChI=1S/C27H26N6O6S/c1-18(2)19-11-12-22(30-17-19)40(35,36)33-24-23(39-21-10-5-4-9-20(21)37-3)27(38-16-7-6-15-34)32-26(31-24)25-28-13-8-14-29-25/h4-5,8-14,17-18,34H,15-16H2,1-3H3,(H,31,32,33)	SRQSESHDJDXUDV-UHFFFAOYSA-N	50124457	5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide::CHEMBL425682	Endothelin-1 receptor			 53							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124457&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10144372	104016772		CHEMBL425682				ZINC03943967	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225538	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCOc1ccccc1)-c1ncccn1	InChI=1S/C35H33N5O6S/c1-35(2,3)25-17-19-27(20-18-25)47(41,42)40-31-30(46-29-16-9-8-15-28(29)43-4)34(39-33(38-31)32-36-21-12-22-37-32)45-24-11-10-23-44-26-13-6-5-7-14-26/h5-9,12-22H,23-24H2,1-4H3,(H,38,39,40)	YZCIBWHZHRZYCF-UHFFFAOYSA-N	50124460	4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy-but-2-ynyloxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL173689	Endothelin-1 receptor			 139							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124460&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10189776	104016775		CHEMBL173689				ZINC28011053	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225539	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCO)-c1ccncc1	InChI=1S/C30H30N4O6S/c1-30(2,3)22-11-13-23(14-12-22)41(36,37)34-28-26(40-25-10-6-5-9-24(25)38-4)29(39-20-8-7-19-35)33-27(32-28)21-15-17-31-18-16-21/h5-6,9-18,35H,19-20H2,1-4H3,(H,32,33,34)	PZBFMEKBVYTVOD-UHFFFAOYSA-N	50124461	4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL173358	Endothelin-1 receptor			 125							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124461&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10281573	104016776		CHEMBL173358				ZINC28019692	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225540	COCC#CCOc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C30H31N5O6S/c1-30(2,3)21-13-15-22(16-14-21)42(36,37)35-26-25(41-24-12-7-6-11-23(24)39-5)29(40-20-9-8-19-38-4)34-28(33-26)27-31-17-10-18-32-27/h6-7,10-18H,19-20H2,1-5H3,(H,33,34,35)	PAFIXHNUVNIVSK-UHFFFAOYSA-N	50124462	4-tert-Butyl-N-[6-(4-methoxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL173743	Endothelin-1 receptor			 13							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124462&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10281943	104016777		CHEMBL173743				ZINC28011059	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225542	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCO)N1CCOCC1	InChI=1S/C25H27N5O7S/c1-18-9-10-21(26-17-18)38(32,33)29-23-22(37-20-8-4-3-7-19(20)34-2)24(36-14-6-5-13-31)28-25(27-23)30-11-15-35-16-12-30/h3-4,7-10,17,31H,11-16H2,1-2H3,(H,27,28,29)	VXJUFLPIZFIKQL-UHFFFAOYSA-N	50124463	5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide::CHEMBL369362	Endothelin-1 receptor			 18							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124463&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10165809	104016778		CHEMBL369362				ZINC28019363	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225545	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCO)-c1ccncc1	InChI=1S/C26H23N5O6S/c1-18-9-10-22(28-17-18)38(33,34)31-25-23(37-21-8-4-3-7-20(21)35-2)26(36-16-6-5-15-32)30-24(29-25)19-11-13-27-14-12-19/h3-4,7-14,17,32H,15-16H2,1-2H3,(H,29,30,31)	PYTGPPKMIDNVTB-UHFFFAOYSA-N	50124466	5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide::CHEMBL175111	Endothelin-1 receptor			 22							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124466&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10302118	104016781		CHEMBL175111				ZINC28089956	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225550	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)NC1CCCCC1)N1CCOCC1	InChI=1S/C32H38N6O8S/c1-23-14-15-27(33-22-23)47(40,41)37-29-28(46-26-13-7-6-12-25(26)42-2)30(36-31(35-29)38-16-20-43-21-17-38)44-18-8-9-19-45-32(39)34-24-10-4-3-5-11-24/h6-7,12-15,22,24H,3-5,10-11,16-21H2,1-2H3,(H,34,39)(H,35,36,37)	HOPRHFCRDCRJAB-UHFFFAOYSA-N	50124469	CHEMBL175278::Cyclohexyl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 753							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124469&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10305181	104016784		CHEMBL175278				ZINC28023059	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225551	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)Nc1ccccc1)N1CCOCC1	InChI=1S/C34H36N6O8S/c1-24(2)25-15-16-29(35-23-25)49(42,43)39-31-30(48-28-14-8-7-13-27(28)44-3)32(38-33(37-31)40-17-21-45-22-18-40)46-19-9-10-20-47-34(41)36-26-11-5-4-6-12-26/h4-8,11-16,23-24H,17-22H2,1-3H3,(H,36,41)(H,37,38,39)	XSAFCBSWMREXMT-UHFFFAOYSA-N	50124470	CHEMBL264035::Phenyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 13							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124470&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10212088	104016785		CHEMBL264035				ZINC28089879	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225553	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C28H25N9O5S/c1-5-14-41-28-24(42-22-9-7-6-8-21(22)40-4)27(35-43(38,39)23-11-10-19(16-30-23)17(2)3)31-25(32-28)18-12-13-29-20(15-18)26-33-36-37-34-26/h1,6-13,15-17H,14H2,2-4H3,(H,31,32,35)(H,33,34,36,37)	BEGQGXHBEYDHFL-UHFFFAOYSA-N	50124476	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL175057	Endothelin-1 receptor			 23							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124476&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10282163	104016791		CHEMBL175057				ZINC28091936	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225554	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1ccnc(CO)c1	InChI=1S/C30H30N4O6S/c1-6-17-39-29-26(40-25-10-8-7-9-24(25)38-5)28(32-27(33-29)20-15-16-31-22(18-20)19-35)34-41(36,37)23-13-11-21(12-14-23)30(2,3)4/h1,7-16,18,35H,17,19H2,2-5H3,(H,32,33,34)	IKSWGOKQGJQKIW-UHFFFAOYSA-N	50124473	4-tert-Butyl-N-[2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL368829	Endothelin-1 receptor			 38							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124473&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385008	104016788		CHEMBL368829				ZINC28089049	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225555	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)N1CCOCC1	InChI=1S/C26H29N5O6S/c1-5-14-36-25-23(37-21-9-7-6-8-20(21)34-4)24(28-26(29-25)31-12-15-35-16-13-31)30-38(32,33)22-11-10-19(17-27-22)18(2)3/h1,6-11,17-18H,12-16H2,2-4H3,(H,28,29,30)	HMDVOILXHRHOGL-UHFFFAOYSA-N	50124475	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-2-morpholin-4-yl-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide::CHEMBL368929	Endothelin-1 receptor			 121							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124475&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385576	104016790		CHEMBL368929				ZINC28018321	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225556	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(C)nc1OCC#CCO	InChI=1S/C22H22N4O6S/c1-15-10-11-19(23-14-15)33(28,29)26-21-20(32-18-9-5-4-8-17(18)30-3)22(25-16(2)24-21)31-13-7-6-12-27/h4-5,8-11,14,27H,12-13H2,1-3H3,(H,24,25,26)	XSBZKVKTYQWLQU-UHFFFAOYSA-N	50124472	5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yl]-amide::CHEMBL177111	Endothelin-1 receptor			 452.0							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124472&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10205429	104016787		CHEMBL177111				ZINC13488265	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225559	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1ccncc1	InChI=1S/C29H28N4O5S/c1-6-19-37-28-25(38-24-10-8-7-9-23(24)36-5)27(31-26(32-28)20-15-17-30-18-16-20)33-39(34,35)22-13-11-21(12-14-22)29(2,3)4/h1,7-18H,19H2,2-5H3,(H,31,32,33)	BUZZXSDSIRQVKH-UHFFFAOYSA-N	50124479	4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL174094	Endothelin-1 receptor			 176							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124479&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384852	104016794		CHEMBL174094				ZINC28011150	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225562	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)Nc1cccnc1)N1CCOCC1	InChI=1S/C31H31N7O8S/c1-22-11-12-26(33-20-22)47(40,41)37-28-27(46-25-10-4-3-9-24(25)42-2)29(36-30(35-28)38-14-18-43-19-15-38)44-16-5-6-17-45-31(39)34-23-8-7-13-32-21-23/h3-4,7-13,20-21H,14-19H2,1-2H3,(H,34,39)(H,35,36,37)	NNXCMHJFFYTMCA-UHFFFAOYSA-N	50124456	CHEMBL176741::Pyridin-3-yl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 21							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124456&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10168597	104016771		CHEMBL176741				ZINC28090905	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225566	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCO)N1CCOCC1	InChI=1S/C29H34N4O7S/c1-29(2,3)21-11-13-22(14-12-21)41(35,36)32-26-25(40-24-10-6-5-9-23(24)37-4)27(39-18-8-7-17-34)31-28(30-26)33-15-19-38-20-16-33/h5-6,9-14,34H,15-20H2,1-4H3,(H,30,31,32)	NXZDWYHCLMUTOJ-UHFFFAOYSA-N	50124480	4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL177203	Endothelin-1 receptor			 155							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124480&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10188517	104016795		CHEMBL177203				ZINC28086037	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225568	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCO)-c1ccncc1	InChI=1S/C28H27N5O6S/c1-19(2)21-10-11-24(30-18-21)40(35,36)33-27-25(39-23-9-5-4-8-22(23)37-3)28(38-17-7-6-16-34)32-26(31-27)20-12-14-29-15-13-20/h4-5,8-15,18-19,34H,16-17H2,1-3H3,(H,31,32,33)	PFRXWKQQCRIVDP-UHFFFAOYSA-N	50124483	5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yl]-amide::CHEMBL368211	Endothelin-1 receptor			 26							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124483&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10144334	104016798		CHEMBL368211				ZINC28018221	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225570	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC=C)-c1ncccn1	InChI=1S/C28H29N5O5S/c1-6-18-37-27-23(38-22-11-8-7-10-21(22)36-5)24(31-26(32-27)25-29-16-9-17-30-25)33-39(34,35)20-14-12-19(13-15-20)28(2,3)4/h6-17H,1,18H2,2-5H3,(H,31,32,33)	ZFRVETWZLIDWRO-UHFFFAOYSA-N	50124484	CHEMBL367339::N-[6-Allyloxy-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-4-tert-butyl-benzenesulfonamide	Endothelin-1 receptor			 373							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124484&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44177614	104016799		CHEMBL367339				ZINC28103942	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225572	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ccnc(c1)-c1nc(=O)o[nH]1	InChI=1S/C27H21N7O7S/c1-4-13-39-26-22(40-20-8-6-5-7-19(20)38-3)25(34-42(36,37)21-10-9-16(2)15-29-21)30-23(31-26)17-11-12-28-18(14-17)24-32-27(35)41-33-24/h1,5-12,14-15H,13H2,2-3H3,(H,30,31,34)(H,32,33,35)	DCVQYDDFMCVONG-UHFFFAOYSA-N	50124494	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-amide::CHEMBL170401	Endothelin-1 receptor			 13							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124494&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10167297	104016809		CHEMBL170401				ZINC28005874	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225573	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1ccnc(c1)-c1nc(=S)o[nH]1	InChI=1S/C29H25N7O6S2/c1-5-14-40-28-24(41-22-9-7-6-8-21(22)39-4)27(36-44(37,38)23-11-10-19(16-31-23)17(2)3)32-25(33-28)18-12-13-30-20(15-18)26-34-29(43)42-35-26/h1,6-13,15-17H,14H2,2-4H3,(H,32,33,36)(H,34,35,43)	HTNBCWLAXCOARB-UHFFFAOYSA-N	50124482	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL176999	Endothelin-1 receptor			 27							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124482&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10168195	104016797		CHEMBL176999				ZINC28088512	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225576	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCOCc1ccccc1)-c1ncccn1	InChI=1S/C36H35N5O6S/c1-36(2,3)27-17-19-28(20-18-27)48(42,43)41-32-31(47-30-16-9-8-15-29(30)44-4)35(40-34(39-32)33-37-21-12-22-38-33)46-24-11-10-23-45-25-26-13-6-5-7-14-26/h5-9,12-22H,23-25H2,1-4H3,(H,39,40,41)	IQDOAXKPCZHWTO-UHFFFAOYSA-N	50124467	CHEMBL139734::N-[6-(4-Benzyloxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-4-tert-butyl-benzenesulfonamide	Endothelin-1 receptor			 1280							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124467&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10122495	104016782		CHEMBL139734				ZINC28019697	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225577	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ncccn1	InChI=1S/C24H20N6O5S/c1-4-14-34-24-20(35-18-9-6-5-8-17(18)33-3)21(28-23(29-24)22-25-12-7-13-26-22)30-36(31,32)19-11-10-16(2)15-27-19/h1,5-13,15H,14H2,2-3H3,(H,28,29,30)	JCGNZDZYBQRIOH-UHFFFAOYSA-N	50124489	5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-amide::CHEMBL369003	Endothelin-1 receptor			 339							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124489&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384557	104016804		CHEMBL369003				ZINC13488266	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225578	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)ncnc1OCC#CCO	InChI=1S/C23H24N4O6S/c1-16(2)17-10-11-20(24-14-17)34(29,30)27-22-21(33-19-9-5-4-8-18(19)31-3)23(26-15-25-22)32-13-7-6-12-28/h4-5,8-11,14-16,28H,12-13H2,1-3H3,(H,25,26,27)	WITCSGJQNAEGBT-UHFFFAOYSA-N	50124490	5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide::CHEMBL170342	Endothelin-1 receptor			 166							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124490&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10140871	104016805		CHEMBL170342				ZINC13488264	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225580	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1ccnc(CO)c1	InChI=1S/C28H27N5O6S/c1-5-14-38-28-25(39-23-9-7-6-8-22(23)37-4)27(31-26(32-28)19-12-13-29-21(15-19)17-34)33-40(35,36)24-11-10-20(16-30-24)18(2)3/h1,6-13,15-16,18,34H,14,17H2,2-4H3,(H,31,32,33)	SIPPOBLYWAIKGU-UHFFFAOYSA-N	50124493	5-Isopropyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide::CHEMBL176482	Endothelin-1 receptor			 24							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124493&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10281192	104016808		CHEMBL176482				ZINC28023113	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225581	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCO)-c1ncccn1	InChI=1S/C25H22N6O6S/c1-17-10-11-20(28-16-17)38(33,34)31-22-21(37-19-9-4-3-8-18(19)35-2)25(36-15-6-5-14-32)30-24(29-22)23-26-12-7-13-27-23/h3-4,7-13,16,32H,14-15H2,1-2H3,(H,29,30,31)	RYBRUNGCKRSHAC-UHFFFAOYSA-N	50124491	5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide::CHEMBL367317	Endothelin-1 receptor			 339							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124491&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10230375	104016806		CHEMBL367317				ZINC28099977	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225582	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)Nc1cnccn1)-c1ccncc1	InChI=1S/C33H30N8O7S/c1-22(2)24-10-11-28(37-20-24)49(43,44)41-31-29(48-26-9-5-4-8-25(26)45-3)32(40-30(39-31)23-12-14-34-15-13-23)46-18-6-7-19-47-33(42)38-27-21-35-16-17-36-27/h4-5,8-17,20-22H,18-19H2,1-3H3,(H,36,38,42)(H,39,40,41)	SWIPVSPLUXWKTL-UHFFFAOYSA-N	50124492	CHEMBL275897::Pyrazin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 14							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124492&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10122675	104016807		CHEMBL275897				ZINC28090139	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225583	CCC#CCOc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C30H31N5O5S/c1-6-7-10-20-39-29-25(40-24-13-9-8-12-23(24)38-5)26(33-28(34-29)27-31-18-11-19-32-27)35-41(36,37)22-16-14-21(15-17-22)30(2,3)4/h8-9,11-19H,6,20H2,1-5H3,(H,33,34,35)	CXADSKYEVCKHHO-UHFFFAOYSA-N	50124488	4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL176650	Endothelin-1 receptor			 59							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124488&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44386161	104016803		CHEMBL176650				ZINC28086223	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225584	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)Nc1ccncc1)N1CCOCC1	InChI=1S/C31H31N7O8S/c1-22-9-10-26(33-21-22)47(40,41)37-28-27(46-25-8-4-3-7-24(25)42-2)29(36-30(35-28)38-15-19-43-20-16-38)44-17-5-6-18-45-31(39)34-23-11-13-32-14-12-23/h3-4,7-14,21H,15-20H2,1-2H3,(H,32,34,39)(H,35,36,37)	PQJLYRULHJYQDW-UHFFFAOYSA-N	50124495	CHEMBL366885::Pyridin-4-yl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 12							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124495&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10233400	104016810		CHEMBL366885				ZINC28091946	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225586	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1ccnc(c1)-c1nc(=O)o[nH]1	InChI=1S/C29H25N7O7S/c1-5-14-41-28-24(42-22-9-7-6-8-21(22)40-4)27(36-44(38,39)23-11-10-19(16-31-23)17(2)3)32-25(33-28)18-12-13-30-20(15-18)26-34-29(37)43-35-26/h1,6-13,15-17H,14H2,2-4H3,(H,32,33,36)(H,34,35,37)	KZSPAFPPOAOZPK-UHFFFAOYSA-N	50124486	5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-2-[2-(5-oxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-6-prop-2-ynyloxy-pyrimidin-4-yl}-amide::CHEMBL366652	Endothelin-1 receptor			 22							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124486&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10282508	104016801		CHEMBL366652				ZINC03944038	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225587	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)Nc1cnccn1)N1CCOCC1	InChI=1S/C32H34N8O8S/c1-22(2)23-10-11-27(35-20-23)49(42,43)39-29-28(48-25-9-5-4-8-24(25)44-3)30(38-31(37-29)40-14-18-45-19-15-40)46-16-6-7-17-47-32(41)36-26-21-33-12-13-34-26/h4-5,8-13,20-22H,14-19H2,1-3H3,(H,34,36,41)(H,37,38,39)	MIOQPXBHUMVZRF-UHFFFAOYSA-N	50124496	CHEMBL368996::Pyrazin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 0.400000							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124496&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44386169	104016811		CHEMBL368996				ZINC28023116	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225588	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1cnccn1	InChI=1S/C26H24N6O5S/c1-5-14-36-26-23(37-21-9-7-6-8-20(21)35-4)25(30-24(31-26)19-16-27-12-13-28-19)32-38(33,34)22-11-10-18(15-29-22)17(2)3/h1,6-13,15-17H,14H2,2-4H3,(H,30,31,32)	KFNDOUZZWQQGSC-UHFFFAOYSA-N	50124501	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-amide::CHEMBL176698	Endothelin-1 receptor			 339							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124501&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385805	104016816		CHEMBL176698				ZINC28087892	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225590	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OC\C=C\C)-c1ncccn1	InChI=1S/C29H31N5O5S/c1-6-7-19-38-28-24(39-23-12-9-8-11-22(23)37-5)25(32-27(33-28)26-30-17-10-18-31-26)34-40(35,36)21-15-13-20(14-16-21)29(2,3)4/h6-18H,19H2,1-5H3,(H,32,33,34)/b7-6+	QQJKIZQTUBPYEK-VOTSOKGWSA-N	50124499	CHEMBL173366::N-[6-But-2-enyloxy-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-4-tert-butyl-benzenesulfonamide	Endothelin-1 receptor			 239							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124499&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384826	104016814		CHEMBL173366				ZINC28014928	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225591	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCOC(=O)Nc1ccccn1)-c1ncccn1	InChI=1S/C35H33N7O7S/c1-35(2,3)24-15-17-25(18-16-24)50(44,45)42-30-29(49-27-13-6-5-12-26(27)46-4)33(41-32(40-30)31-37-20-11-21-38-31)47-22-9-10-23-48-34(43)39-28-14-7-8-19-36-28/h5-8,11-21H,22-23H2,1-4H3,(H,36,39,43)(H,40,41,42)	CQOFOENPMPKYGT-UHFFFAOYSA-N	50124500	CHEMBL368860::Pyridin-2-yl-carbamic acid 4-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 293							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124500&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10168939	104016815		CHEMBL368860				ZINC28088679	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225592	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1ncccn1	InChI=1S/C28H27N5O5S/c1-6-18-37-27-23(38-22-11-8-7-10-21(22)36-5)24(31-26(32-27)25-29-16-9-17-30-25)33-39(34,35)20-14-12-19(13-15-20)28(2,3)4/h1,7-17H,18H2,2-5H3,(H,31,32,33)	SHMVBNRYGITUQO-UHFFFAOYSA-N	50124497	4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL175435	Endothelin-1 receptor			 97							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124497&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9807456	104016812		CHEMBL175435				ZINC28109792	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225594	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)Nc1ccccn1)-c1ccncc1	InChI=1S/C34H31N7O7S/c1-23(2)25-13-14-29(37-22-25)49(43,44)41-32-30(48-27-11-5-4-10-26(27)45-3)33(40-31(39-32)24-15-18-35-19-16-24)46-20-8-9-21-47-34(42)38-28-12-6-7-17-36-28/h4-7,10-19,22-23H,20-21H2,1-3H3,(H,36,38,42)(H,39,40,41)	MRZPJCAABGPJED-UHFFFAOYSA-N	50124498	CHEMBL368386::Pyridin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 7							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124498&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10190108	104016813		CHEMBL368386				ZINC03964062	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225598	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCOC(=O)Nc1cnccn1)-c1ncccn1	InChI=1S/C34H32N8O7S/c1-34(2,3)23-12-14-24(15-13-23)50(44,45)42-29-28(49-26-11-6-5-10-25(26)46-4)32(41-31(40-29)30-37-16-9-17-38-30)47-20-7-8-21-48-33(43)39-27-22-35-18-19-36-27/h5-6,9-19,22H,20-21H2,1-4H3,(H,36,39,43)(H,40,41,42)	QMGWFTFOQBFMKK-UHFFFAOYSA-N	50124458	CHEMBL367767::Pyrazin-2-yl-carbamic acid 4-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 204							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124458&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10212163	104016773		CHEMBL367767				ZINC28013007	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225599	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C26H21N9O5S/c1-4-13-39-26-22(40-20-8-6-5-7-19(20)38-3)25(33-41(36,37)21-10-9-16(2)15-28-21)29-23(30-26)17-11-12-27-18(14-17)24-31-34-35-32-24/h1,5-12,14-15H,13H2,2-3H3,(H,29,30,33)(H,31,32,34,35)	NZOSZZWWOMARMH-UHFFFAOYSA-N	50124487	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL176664	Endothelin-1 receptor			 5							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124487&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10210086	104016802		CHEMBL176664				ZINC28086530	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225600	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1cnccn1	InChI=1S/C28H27N5O5S/c1-6-17-37-27-24(38-23-10-8-7-9-22(23)36-5)26(31-25(32-27)21-18-29-15-16-30-21)33-39(34,35)20-13-11-19(12-14-20)28(2,3)4/h1,7-16,18H,17H2,2-5H3,(H,31,32,33)	WLIQAZXJDQKSEC-UHFFFAOYSA-N	50124477	4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyrazin-2-yl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL173465	Endothelin-1 receptor			 186							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124477&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384966	104016792		CHEMBL173465				ZINC28018266	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225603	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)Nc1ccccc1)N1CCOCC1	InChI=1S/C32H32N6O8S/c1-23-14-15-27(33-22-23)47(40,41)37-29-28(46-26-13-7-6-12-25(26)42-2)30(36-31(35-29)38-16-20-43-21-17-38)44-18-8-9-19-45-32(39)34-24-10-4-3-5-11-24/h3-7,10-15,22H,16-21H2,1-2H3,(H,34,39)(H,35,36,37)	CKAWNKDSMUUPOR-UHFFFAOYSA-N	50124503	CHEMBL163638::Phenyl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 18							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124503&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10211772	104016818		CHEMBL163638				ZINC28090917	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225606	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1ncccn1	InChI=1S/C26H24N6O5S/c1-5-15-36-26-22(37-20-10-7-6-9-19(20)35-4)23(30-25(31-26)24-27-13-8-14-28-24)32-38(33,34)21-12-11-18(16-29-21)17(2)3/h1,6-14,16-17H,15H2,2-4H3,(H,30,31,32)	QHNZRGHKEBXFTP-UHFFFAOYSA-N	50124505	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-[2,2']bipyrimidinyl-4-yl]-amide::CHEMBL172184	Endothelin-1 receptor			 96							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124505&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384766	104016820		CHEMBL172184				ZINC28015610	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225607	CCCCNC(=O)OCC#CCOc1nc(nc(NS(=O)(=O)c2ccc(cn2)C(C)C)c1Oc1ccccc1OC)-c1ccncc1	InChI=1S/C33H36N6O7S/c1-5-6-17-35-33(40)45-21-10-9-20-44-32-29(46-27-12-8-7-11-26(27)43-4)31(37-30(38-32)24-15-18-34-19-16-24)39-47(41,42)28-14-13-25(22-36-28)23(2)3/h7-8,11-16,18-19,22-23H,5-6,17,20-21H2,1-4H3,(H,35,40)(H,37,38,39)	UUIMPPMXRVSIPX-UHFFFAOYSA-N	50124459	Butyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester::CHEMBL368383	Endothelin-1 receptor			 157							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124459&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10122442	104016774		CHEMBL368383				ZINC28009695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225610	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C33H35N7O8S/c1-23(2)24-13-14-28(35-22-24)49(42,43)39-30-29(48-26-11-5-4-10-25(26)44-3)31(38-32(37-30)40-16-20-45-21-17-40)46-18-8-9-19-47-33(41)36-27-12-6-7-15-34-27/h4-7,10-15,22-23H,16-21H2,1-3H3,(H,34,36,41)(H,37,38,39)	ITRTVLHSTSAZIL-UHFFFAOYSA-N	50124474	CHEMBL94786::Pyridin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 1							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124474&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10146640	104016789		CHEMBL94786				ZINC28023121	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225611	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CC)-c1ncccn1	InChI=1S/C29H29N5O5S/c1-6-7-19-38-28-24(39-23-12-9-8-11-22(23)37-5)25(32-27(33-28)26-30-17-10-18-31-26)34-40(35,36)21-15-13-20(14-16-21)29(2,3)4/h8-18H,19H2,1-5H3,(H,32,33,34)	LQWPXZAKPMZPOE-UHFFFAOYSA-N	50124502	4-tert-Butyl-N-[6-but-2-ynyloxy-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL174607	Endothelin-1 receptor			 85							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124502&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384715	104016817		CHEMBL174607				ZINC28019540	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225617	CC\C=C\COc1nc(nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C30H33N5O5S/c1-6-7-10-20-39-29-25(40-24-13-9-8-12-23(24)38-5)26(33-28(34-29)27-31-18-11-19-32-27)35-41(36,37)22-16-14-21(15-17-22)30(2,3)4/h7-19H,6,20H2,1-5H3,(H,33,34,35)/b10-7+	YHQPSGDHTOZVQM-JXMROGBWSA-N	50124478	4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-enyloxy-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL175005	Endothelin-1 receptor			 165							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124478&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44386162	104016793		CHEMBL175005				ZINC28093693	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225620	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCC#CCO	InChI=1S/C25H27N3O6S/c1-25(2,3)18-11-13-19(14-12-18)35(30,31)28-23-22(34-21-10-6-5-9-20(21)32-4)24(27-17-26-23)33-16-8-7-15-29/h5-6,9-14,17,29H,15-16H2,1-4H3,(H,26,27,28)	XGEPLEYWMXVDFS-UHFFFAOYSA-N	50124455	4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL173721	Endothelin-1 receptor			 561							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124455&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10185233	104016770		CHEMBL173721				ZINC13488263	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225622	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ccnc(c1)-c1nc(=S)o[nH]1	InChI=1S/C27H21N7O6S2/c1-4-13-38-26-22(39-20-8-6-5-7-19(20)37-3)25(34-42(35,36)21-10-9-16(2)15-29-21)30-23(31-26)17-11-12-28-18(14-17)24-32-27(41)40-33-24/h1,5-12,14-15H,13H2,2-3H3,(H,30,31,34)(H,32,33,41)	VVHUUKQWKHDRBQ-UHFFFAOYSA-N	50124507	5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL367686	Endothelin-1 receptor			 12							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124507&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10304227	104016822		CHEMBL367686				ZINC28017936	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225630	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCO)N1CCOCC1	InChI=1S/C27H31N5O7S/c1-19(2)20-10-11-23(28-18-20)40(34,35)31-25-24(39-22-9-5-4-8-21(22)36-3)26(38-15-7-6-14-33)30-27(29-25)32-12-16-37-17-13-32/h4-5,8-11,18-19,33H,12-17H2,1-3H3,(H,29,30,31)	DUZPNAKTFLDXQA-UHFFFAOYSA-N	50124504	5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yl]-amide::CHEMBL368828	Endothelin-1 receptor			 16							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124504&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10231591	104016819		CHEMBL368828				ZINC03943969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225631	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ccncc1	InChI=1S/C25H21N5O5S/c1-4-15-34-25-22(35-20-8-6-5-7-19(20)33-3)24(28-23(29-25)18-11-13-26-14-12-18)30-36(31,32)21-10-9-17(2)16-27-21/h1,5-14,16H,15H2,2-3H3,(H,28,29,30)	CSKOXMVENMNMHJ-UHFFFAOYSA-N	50124468	5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-amide::CHEMBL174326	Endothelin-1 receptor			 94							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124468&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44386002	104016783		CHEMBL174326				ZINC13488267	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225632	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 40							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225633	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#C)-c1ccncc1	InChI=1S/C27H25N5O5S/c1-5-16-36-27-24(37-22-9-7-6-8-21(22)35-4)26(30-25(31-27)19-12-14-28-15-13-19)32-38(33,34)23-11-10-20(17-29-23)18(2)3/h1,6-15,17-18H,16H2,2-4H3,(H,30,31,32)	OZBAKTZMSBVKFA-UHFFFAOYSA-N	50124464	5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-pyridin-4-yl-pyrimidin-4-yl]-amide::CHEMBL177143	Endothelin-1 receptor			 125							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124464&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385586	104016779		CHEMBL177143				ZINC28023094	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225634	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#C)-c1ccnc(c1)-c1nc(=S)o[nH]1	InChI=1S/C31H28N6O6S2/c1-6-17-41-29-25(42-24-10-8-7-9-23(24)40-5)28(37-45(38,39)21-13-11-20(12-14-21)31(2,3)4)33-26(34-29)19-15-16-32-22(18-19)27-35-30(44)43-36-27/h1,7-16,18H,17H2,2-5H3,(H,33,34,37)(H,35,36,44)	QSFFFSPNGBKTGJ-UHFFFAOYSA-N	50124506	4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-2-[2-(5-thioxo-2,5-dihydro-[1,2,4]oxadiazol-3-yl)-pyridin-4-yl]-pyrimidin-4-yl}-benzenesulfonamide::CHEMBL366797	Endothelin-1 receptor			 84							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124506&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384611	104016821		CHEMBL366797				ZINC28018969	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225635	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)Nc1ccccc1)-c1ccncc1	InChI=1S/C35H32N6O7S/c1-24(2)26-15-16-30(37-23-26)49(43,44)41-33-31(48-29-14-8-7-13-28(29)45-3)34(40-32(39-33)25-17-19-36-20-18-25)46-21-9-10-22-47-35(42)38-27-11-5-4-6-12-27/h4-8,11-20,23-24H,21-22H2,1-3H3,(H,38,42)(H,39,40,41)	DTDRDEIFMKNNTL-UHFFFAOYSA-N	50124485	CHEMBL367036::Phenyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-pyridin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 35							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124485&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10305334	104016800		CHEMBL367036				ZINC28009688	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225640	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CCO)-c1ncccn1	InChI=1S/C29H29N5O6S/c1-29(2,3)20-12-14-21(15-13-20)41(36,37)34-25-24(40-23-11-6-5-10-22(23)38-4)28(39-19-8-7-18-35)33-27(32-25)26-30-16-9-17-31-26/h5-6,9-17,35H,18-19H2,1-4H3,(H,32,33,34)	FPZOGKSKYWZFIO-UHFFFAOYSA-N	50124471	4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide::CHEMBL367382	Endothelin-1 receptor			 51							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124471&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10281606	104016786		CHEMBL367382				ZINC28021407	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225641	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#C)-c1ccnc(CO)c1	InChI=1S/C26H23N5O6S/c1-4-13-36-26-23(37-21-8-6-5-7-20(21)35-3)25(31-38(33,34)22-10-9-17(2)15-28-22)29-24(30-26)18-11-12-27-19(14-18)16-32/h1,5-12,14-15,32H,13,16H2,2-3H3,(H,29,30,31)	WOOHTOSSXGHYSO-UHFFFAOYSA-N	50124481	5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymethyl-pyridin-4-yl)-5-(2-methoxy-phenoxy)-6-prop-2-ynyloxy-pyrimidin-4-yl]-amide::CHEMBL176963	Endothelin-1 receptor			 11							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124481&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385162	104016796		CHEMBL176963				ZINC28019373	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50225643	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC#CCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C31H31N7O8S/c1-22-12-13-26(33-21-22)47(40,41)37-28-27(46-24-10-4-3-9-23(24)42-2)29(36-30(35-28)38-15-19-43-20-16-38)44-17-7-8-18-45-31(39)34-25-11-5-6-14-32-25/h3-6,9-14,21H,15-20H2,1-2H3,(H,32,34,39)(H,35,36,37)	PIWOCJNYDKRQRS-UHFFFAOYSA-N	50124465	CHEMBL367453::Pyridin-2-yl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-but-2-ynyl ester	Endothelin-1 receptor			 1							ChEMBL	10.1016/s0960-894x(02)01084-3	10.7270/Q28C9VK8	12617929			Bolli, MH; Boss, C; Clozel, M; Fischli, W; Hess, P; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124465&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10211781	104016780		CHEMBL367453				ZINC28090911	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50212867	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H34N4O4S/c1-4-5-12-26-30-29(17-8-9-18-29)28(34)33(26)19-22-13-15-23(16-14-22)24-10-6-7-11-25(24)38(35,36)32-27-20(2)21(3)31-37-27/h6-7,10-11,13-16,32H,4-5,8-9,12,17-19H2,1-3H3	RAIIKBZUVAKIAR-UHFFFAOYSA-N	50117911	4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL126755	Endothelin-1 receptor		 39								ChEMBL	10.1021/jm020138n	10.7270/Q2Z60NDM	12190306			Murugesan, N; Tellew, JE; Gu, Z; Kunst, BL; Fadnis, L; Cornelius, LA; Baska, RA; Yang, Y; Beyer, SM; Monshizadegan, H; Dickinson, KE; Panchal, B; Valentine, MT; Chong, S; Morrison, RA; Carlson, KE; Powell, JR; Moreland, S; Barrish, JC; Kowala, MC; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117911&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11813485	104011319		CHEMBL126755				ZINC27298769	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50212874	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C36H45N5O5S/c1-6-7-14-31-37-36(17-10-11-18-36)34(43)41(31)22-26-15-16-28(27(21-26)23-40-20-19-35(4,5)33(40)42)29-12-8-9-13-30(29)47(44,45)39-32-24(2)25(3)38-46-32/h8-9,12-13,15-16,21,39H,6-7,10-11,14,17-20,22-23H2,1-5H3	NBDFXMDYBLSGLX-UHFFFAOYSA-N	50117910	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2''-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2'-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::BMS-248360::CHEMBL11706	Endothelin-1 receptor		 1.9								ChEMBL	10.1021/jm020138n	10.7270/Q2Z60NDM	12190306			Murugesan, N; Tellew, JE; Gu, Z; Kunst, BL; Fadnis, L; Cornelius, LA; Baska, RA; Yang, Y; Beyer, SM; Monshizadegan, H; Dickinson, KE; Panchal, B; Valentine, MT; Chong, S; Morrison, RA; Carlson, KE; Powell, JR; Moreland, S; Barrish, JC; Kowala, MC; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117910&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895957	104011318		CHEMBL11706				ZINC26026608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50212863	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-26-20/h3-12,23H,1-2H3	LJGUZUROJOJEMI-UHFFFAOYSA-N	50091105	4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide::BMS-193884::CHEMBL24461	Endothelin-1 receptor		 1.4								ChEMBL	10.1021/jm020138n	10.7270/Q2Z60NDM	12190306			Murugesan, N; Tellew, JE; Gu, Z; Kunst, BL; Fadnis, L; Cornelius, LA; Baska, RA; Yang, Y; Beyer, SM; Monshizadegan, H; Dickinson, KE; Panchal, B; Valentine, MT; Chong, S; Morrison, RA; Carlson, KE; Powell, JR; Moreland, S; Barrish, JC; Kowala, MC; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9843631	103989493		CHEMBL24461				ZINC00836695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50212864	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C38H42N4O6S/c1-7-9-28-19-26(21-42-34(8-2)40-35-24(5)18-25(6)39-37(35)42)10-16-31(28)48-36(29-13-17-32-33(20-29)47-22-46-32)38(43)41-49(44,45)30-14-11-27(12-15-30)23(3)4/h10-20,23,36H,7-9,21-22H2,1-6H3,(H,41,43)	NTQWAQFOJQQOTK-UHFFFAOYSA-N	50117909	CHEMBL278176::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 24							ChEMBL	10.1021/jm020138n	10.7270/Q2Z60NDM	12190306			Murugesan, N; Tellew, JE; Gu, Z; Kunst, BL; Fadnis, L; Cornelius, LA; Baska, RA; Yang, Y; Beyer, SM; Monshizadegan, H; Dickinson, KE; Panchal, B; Valentine, MT; Chong, S; Morrison, RA; Carlson, KE; Powell, JR; Moreland, S; Barrish, JC; Kowala, MC; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117909&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9896251	104011317		CHEMBL278176				ZINC43317880	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50214223	O=C(Cc1ccccc1)NC1CCN(CCCN2C(=O)COc3ccccc23)CC1	InChI=1S/C24H29N3O3/c28-23(17-19-7-2-1-3-8-19)25-20-11-15-26(16-12-20)13-6-14-27-21-9-4-5-10-22(21)30-18-24(27)29/h1-5,7-10,20H,6,11-18H2,(H,25,28)	FLGSUSWMWSZVMP-UHFFFAOYSA-N	50326218	CHEMBL1242923::N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]-piperidin-4-yl}-2-phenylacetamide	Endothelin-1 receptor		<1000								ChEMBL	10.1021/jm100697g	10.7270/Q2765G9K	20684563			Sams, AG; Hentzer, M; Mikkelsen, GK; Larsen, K; Bundgaard, C; Plath, N; Christoffersen, CT; Bang-Andersen, B	H. Lundbeck A/S	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326218&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44207909	123105333		CHEMBL1242923		5435		ZINC64573958	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50238101	CCCOc1ccc2n(Cc3ccc4OCOc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1	InChI=1S/C27H23NO7/c1-2-9-31-18-5-6-20-19(12-18)25(17-4-8-22-24(11-17)35-15-33-22)26(27(29)30)28(20)13-16-3-7-21-23(10-16)34-14-32-21/h3-8,10-12H,2,9,13-15H2,1H3,(H,29,30)	LQWGCVIETCFLOP-UHFFFAOYSA-N	50069567	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL10218	Endothelin-1 receptor			 250							ChEMBL	10.1021/jm0300429	10.7270/Q2W37VQ4	12852756			Lewell, XQ; Jones, AC; Bruce, CL; Harper, G; Jones, MM; McLay, IM; Bradshaw, J	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069567&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266552	103963627		CHEMBL10218				ZINC26005428	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50238102	CCCOc1ccc2n(Cc3ccc4nonc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1	InChI=1S/C26H21N3O6/c1-2-9-32-17-5-7-21-18(12-17)24(16-4-8-22-23(11-16)34-14-33-22)25(26(30)31)29(21)13-15-3-6-19-20(10-15)28-35-27-19/h3-8,10-12H,2,9,13-14H2,1H3,(H,30,31)	PDDMKQWEOKOAQN-UHFFFAOYSA-N	50069574	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]oxadiazol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL69664	Endothelin-1 receptor			 2500							ChEMBL	10.1021/jm0300429	10.7270/Q2W37VQ4	12852756			Lewell, XQ; Jones, AC; Bruce, CL; Harper, G; Jones, MM; McLay, IM; Bradshaw, J	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069574&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44309488	103963634		CHEMBL69664				ZINC26272572	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50238103	COc1cc2c(c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OC)-c1ccc2OCOc2c1	InChI=1S/C26H21NO8/c1-30-20-9-16-17(10-21(20)31-2)27(11-14-3-5-18-22(7-14)34-12-32-18)25(26(28)29)24(16)15-4-6-19-23(8-15)35-13-33-19/h3-10H,11-13H2,1-2H3,(H,28,29)	QXUMYHYMXFAQPE-UHFFFAOYSA-N	50069565	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL276638	Endothelin-1 receptor			 150							ChEMBL	10.1021/jm0300429	10.7270/Q2W37VQ4	12852756			Lewell, XQ; Jones, AC; Bruce, CL; Harper, G; Jones, MM; McLay, IM; Bradshaw, J	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069565&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266646	103963625		CHEMBL276638				ZINC26006962	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50238104	COc1cc2c(c(C(O)=O)n(Cc3ccc4nsnc4c3)c2cc1OC)-c1ccc2OCOc2c1	InChI=1S/C25H19N3O6S/c1-31-20-9-15-18(10-21(20)32-2)28(11-13-3-5-16-17(7-13)27-35-26-16)24(25(29)30)23(15)14-4-6-19-22(8-14)34-12-33-19/h3-10H,11-12H2,1-2H3,(H,29,30)	WBPPFODALXOLOK-UHFFFAOYSA-N	50069571	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5-ylmethyl-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL68557	Endothelin-1 receptor			 33							ChEMBL	10.1021/jm0300429	10.7270/Q2W37VQ4	12852756			Lewell, XQ; Jones, AC; Bruce, CL; Harper, G; Jones, MM; McLay, IM; Bradshaw, J	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069571&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44310016	103963631		CHEMBL68557				ZINC26281872	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50238105	CCCOc1ccc2n(Cc3ccc4nsnc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1	InChI=1S/C26H21N3O5S/c1-2-9-32-17-5-7-21-18(12-17)24(16-4-8-22-23(11-16)34-14-33-22)25(26(30)31)29(21)13-15-3-6-19-20(10-15)28-35-27-19/h3-8,10-12H,2,9,13-14H2,1H3,(H,30,31)	LQKHSTBTPGBUTB-UHFFFAOYSA-N	50069573	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,2,5]thiadiazol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL69150	Endothelin-1 receptor			 97							ChEMBL	10.1021/jm0300429	10.7270/Q2W37VQ4	12852756			Lewell, XQ; Jones, AC; Bruce, CL; Harper, G; Jones, MM; McLay, IM; Bradshaw, J	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069573&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10195727	103963633		CHEMBL69150				ZINC01545587	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50232104	CCOc1ccc(cc1)-c1cc(C)nc(OC(C(O)=O)C(C)(c2ccccc2)c2ccccc2)n1	InChI=1S/C29H28N2O4/c1-4-34-24-17-15-21(16-18-24)25-19-20(2)30-28(31-25)35-26(27(32)33)29(3,22-11-7-5-8-12-22)23-13-9-6-10-14-23/h5-19,26H,4H2,1-3H3,(H,32,33)	KWXXXHXCVVFIMQ-UHFFFAOYSA-N	50127760	2-[4-(4-Ethoxy-phenyl)-6-methyl-pyrimidin-2-yloxy]-3,3-diphenyl-butyric acid::CHEMBL46311	Endothelin-1 receptor		 2								ChEMBL	10.1016/s0960-894x(03)00236-1	10.7270/Q2DJ5F1K	12729650			Lange, UE; Braje, WM; Amberg, W; Kettschau, G	BASF AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127760&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10096179	104019585		CHEMBL46311				ZINC13489783	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227286	CCCc1nc(CC)c(C(=O)N(C)C)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H35N5O4S/c1-7-11-26-30-24(8-2)27(29(35)33(5)6)34(26)18-21-14-16-22(17-15-21)23-12-9-10-13-25(23)39(36,37)32-28-19(3)20(4)31-38-28/h9-10,12-17,32H,7-8,11,18H2,1-6H3	FCUQWHAINXOYOX-UHFFFAOYSA-N	50125342	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid dimethylamide::CHEMBL12102	Endothelin-1 receptor		 55								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125342&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10166104	104017569		CHEMBL12102				ZINC26028549	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227287	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(COC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C31H36N4O5S/c1-5-10-29-32-26-12-7-8-13-27(36)30(26)35(29)18-22-15-16-24(23(17-22)19-39-4)25-11-6-9-14-28(25)41(37,38)34-31-20(2)21(3)33-40-31/h6,9,11,14-17,34H,5,7-8,10,12-13,18-19H2,1-4H3	NTIXHLLTWTYLBJ-UHFFFAOYSA-N	50125340	2'-Methoxymethyl-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL268706	Endothelin-1 receptor		 17								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125340&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			17979733	104017567		CHEMBL268706				ZINC26027649	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227291	CCCc1nc(CC)c(C(=O)NC)n1Cc1ccc(c(C)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H35N5O4S/c1-7-11-26-31-24(8-2)27(28(35)30-6)34(26)17-21-14-15-22(18(3)16-21)23-12-9-10-13-25(23)39(36,37)33-29-19(4)20(5)32-38-29/h9-10,12-16,33H,7-8,11,17H2,1-6H3,(H,30,35)	XINKQDLHXXVNGY-UHFFFAOYSA-N	50125345	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-methyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid methylamide::CHEMBL266628	Endothelin-1 receptor		 5								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125345&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9985001	104017572		CHEMBL266628				ZINC01492380	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227295	CCCc1nc(CC)c(C(=O)NC)n1Cc1ccc(c(COCC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C31H39N5O5S/c1-7-12-28-33-26(8-2)29(30(37)32-6)36(28)18-22-15-16-24(23(17-22)19-40-9-3)25-13-10-11-14-27(25)42(38,39)35-31-20(4)21(5)34-41-31/h10-11,13-17,35H,7-9,12,18-19H2,1-6H3,(H,32,37)	OYVJMOMBUZRBJY-UHFFFAOYSA-N	50125348	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-ethoxymethyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid methylamide::CHEMBL12557	Endothelin-1 receptor		 22								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125348&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			20747573	104017575		CHEMBL12557				ZINC36238173	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227296	CCCc1nc(Cl)c(C(=O)OC)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C26H27ClN4O5S/c1-5-8-22-28-24(27)23(26(32)35-4)31(22)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)37(33,34)30-25-16(2)17(3)29-36-25/h6-7,9-14,30H,5,8,15H2,1-4H3	XLCKUSNCRBAKDZ-UHFFFAOYSA-N	50125349	5-Chloro-3-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-2-propyl-3H-imidazole-4-carboxylic acid methyl ester::CHEMBL12172	Endothelin-1 receptor		 460								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125349&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10280562	104017576		CHEMBL12172				ZINC36238182	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227299	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(c(COCC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H37N5O5S/c1-6-11-27-32-25(7-2)28(29(31)36)35(27)17-21-14-15-23(22(16-21)18-39-8-3)24-12-9-10-13-26(24)41(37,38)34-30-19(4)20(5)33-40-30/h9-10,12-16,34H,6-8,11,17-18H2,1-5H3,(H2,31,36)	YCNOAAZOGKEPCU-UHFFFAOYSA-N	50125350	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-ethoxymethyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12175	Endothelin-1 receptor		 20								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125350&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22574798	104017577		CHEMBL12175				ZINC36238175	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227301	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(CO)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H34N4O5S/c1-4-9-28-31-25-11-6-7-12-26(36)29(25)34(28)17-21-14-15-23(22(16-21)18-35)24-10-5-8-13-27(24)40(37,38)33-30-19(2)20(3)32-39-30/h5,8,10,13-16,33,35H,4,6-7,9,11-12,17-18H2,1-3H3	JBRKIZWDQQOPCK-UHFFFAOYSA-N	50125347	2'-Hydroxymethyl-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL11528	Endothelin-1 receptor		 14								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125347&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10166561	104017574		CHEMBL11528				ZINC26024580	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227302	CCCc1nc(Cl)c(C(N)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C25H26ClN5O4S/c1-4-7-21-28-23(26)22(24(27)32)31(21)14-17-10-12-18(13-11-17)19-8-5-6-9-20(19)36(33,34)30-25-15(2)16(3)29-35-25/h5-6,8-13,30H,4,7,14H2,1-3H3,(H2,27,32)	XYHBLDIJAJYURE-UHFFFAOYSA-N	50125346	5-Chloro-3-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12333	Endothelin-1 receptor		 40								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125346&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18004820	104017573		CHEMBL12333				ZINC36238181	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227304	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(C)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H34N4O4S/c1-5-10-28-31-25-12-7-8-13-26(35)29(25)34(28)18-22-15-16-23(19(2)17-22)24-11-6-9-14-27(24)39(36,37)33-30-20(3)21(4)32-38-30/h6,9,11,14-17,33H,5,7-8,10,12-13,18H2,1-4H3	GUILESAVAVIDIH-UHFFFAOYSA-N	50125352	2'-Methyl-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL12013	Endothelin-1 receptor		 13								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125352&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10209324	104017579		CHEMBL12013				ZINC26028557	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227305	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(c(Cl)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C27H30ClN5O4S/c1-5-9-24-30-22(6-2)25(26(29)34)33(24)15-18-12-13-19(21(28)14-18)20-10-7-8-11-23(20)38(35,36)32-27-16(3)17(4)31-37-27/h7-8,10-14,32H,5-6,9,15H2,1-4H3,(H2,29,34)	JGWYBBRQGZMTJS-UHFFFAOYSA-N	50125353	3-[2-Chloro-2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12348	Endothelin-1 receptor		 700								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125353&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			20747572	104017580		CHEMBL12348				ZINC36238178	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227307	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(F)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H31FN4O4S/c1-4-9-27-31-24-11-6-7-12-25(35)28(24)34(27)17-20-14-15-21(23(30)16-20)22-10-5-8-13-26(22)39(36,37)33-29-18(2)19(3)32-38-29/h5,8,10,13-16,33H,4,6-7,9,11-12,17H2,1-3H3	WJGSUHRNYRVLRY-UHFFFAOYSA-N	50125355	2'-Fluoro-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL12590	Endothelin-1 receptor		 20								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125355&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			17979749	104017582		CHEMBL12590				ZINC36238170	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227309	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(c(COCCF)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H36FN5O5S/c1-5-9-27-33-25(6-2)28(29(32)37)36(27)17-21-12-13-23(22(16-21)18-40-15-14-31)24-10-7-8-11-26(24)42(38,39)35-30-19(3)20(4)34-41-30/h7-8,10-13,16,35H,5-6,9,14-15,17-18H2,1-4H3,(H2,32,37)	POUZXGIFPZCULZ-UHFFFAOYSA-N	50125356	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-(2-fluoro-ethoxymethyl)-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12588	Endothelin-1 receptor		 8								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125356&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22574645	104017583		CHEMBL12588				ZINC36238166	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227313	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H32N4O4S/c1-4-9-27-30-24-11-6-7-12-25(34)28(24)33(27)18-21-14-16-22(17-15-21)23-10-5-8-13-26(23)38(35,36)32-29-19(2)20(3)31-37-29/h5,8,10,13-17,32H,4,6-7,9,11-12,18H2,1-3H3	BZKRFADHPWYAAS-UHFFFAOYSA-N	50125341	4'-(8-Oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL12779	Endothelin-1 receptor		 105								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125341&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44267891	104017568		CHEMBL12779				ZINC36238183	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227314	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(c(COC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H35N5O5S/c1-6-10-26-31-24(7-2)27(28(30)35)34(26)16-20-13-14-22(21(15-20)17-38-5)23-11-8-9-12-25(23)40(36,37)33-29-18(3)19(4)32-39-29/h8-9,11-15,33H,6-7,10,16-17H2,1-5H3,(H2,30,35)	SOCAZRKGNBLYSF-UHFFFAOYSA-N	50125339	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-methoxymethyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL11840	Endothelin-1 receptor		 4								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125339&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			20747574	104017566		CHEMBL11840				ZINC26025156	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227315	CCCc1nc(Cl)c(C(C)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C26H27ClN4O4S/c1-5-8-23-28-25(27)24(18(4)32)31(23)15-19-11-13-20(14-12-19)21-9-6-7-10-22(21)36(33,34)30-26-16(2)17(3)29-35-26/h6-7,9-14,30H,5,8,15H2,1-4H3	HDRDIUYQWRKIFA-UHFFFAOYSA-N	50125351	4'-(5-Acetyl-4-chloro-2-propyl-imidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL274154	Endothelin-1 receptor		 40								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125351&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10208527	104017578		CHEMBL274154				ZINC13488357	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227316	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C27H31N5O4S/c1-5-9-24-29-22(6-2)25(26(28)33)32(24)16-19-12-14-20(15-13-19)21-10-7-8-11-23(21)37(34,35)31-27-17(3)18(4)30-36-27/h7-8,10-15,31H,5-6,9,16H2,1-4H3,(H2,28,33)	IIRPGRQYSBGVCA-UHFFFAOYSA-N	50125358	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12592	Endothelin-1 receptor		 55								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125358&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			17979745	104017585		CHEMBL12592				ZINC13488356	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227317	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(c(C)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C28H33N5O4S/c1-6-10-25-30-23(7-2)26(27(29)34)33(25)16-20-13-14-21(17(3)15-20)22-11-8-9-12-24(22)38(35,36)32-28-18(4)19(5)31-37-28/h8-9,11-15,32H,6-7,10,16H2,1-5H3,(H2,29,34)	VVGRGSRZVVXEEN-UHFFFAOYSA-N	50125359	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-methyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12106	Endothelin-1 receptor		 5								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125359&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9871837	104017586		CHEMBL12106				ZINC01492381	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227318	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C36H43N5O5S/c1-6-11-32-37-29-13-8-9-14-30(42)33(29)41(32)21-25-16-17-27(26(20-25)22-40-19-18-36(4,5)35(40)43)28-12-7-10-15-31(28)47(44,45)39-34-23(2)24(3)38-46-34/h7,10,12,15-17,20,39H,6,8-9,11,13-14,18-19,21-22H2,1-5H3	MBQOXADHKNARRP-UHFFFAOYSA-N	50125343	2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL12703	Endothelin-1 receptor		 1								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125343&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			17979744	104017570		CHEMBL12703				ZINC49853551	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227320	CCCc1nc(CC)c(C(=O)NC)n1Cc1ccc(c(COC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H37N5O5S/c1-7-11-27-32-25(8-2)28(29(36)31-5)35(27)17-21-14-15-23(22(16-21)18-39-6)24-12-9-10-13-26(24)41(37,38)34-30-19(3)20(4)33-40-30/h9-10,12-16,34H,7-8,11,17-18H2,1-6H3,(H,31,36)	MNJMLQKJRCXWRC-UHFFFAOYSA-N	50125361	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-methoxymethyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid methylamide::CHEMBL275545	Endothelin-1 receptor		 7								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125361&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			20747575	104017588		CHEMBL275545				ZINC36238164	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227322	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(COCC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C32H38N4O5S/c1-5-11-30-33-27-13-8-9-14-28(37)31(27)36(30)19-23-16-17-25(24(18-23)20-40-6-2)26-12-7-10-15-29(26)42(38,39)35-32-21(3)22(4)34-41-32/h7,10,12,15-18,35H,5-6,8-9,11,13-14,19-20H2,1-4H3	SITSOAKGHRDHAJ-UHFFFAOYSA-N	50125360	2'-Ethoxymethyl-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL429037	Endothelin-1 receptor		 20								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125360&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44267860	104017587		CHEMBL429037				ZINC26024728	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227323	CCCCc1nc(Cl)c(C(N)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C26H28ClN5O4S/c1-4-5-10-22-29-24(27)23(25(28)33)32(22)15-18-11-13-19(14-12-18)20-8-6-7-9-21(20)37(34,35)31-26-16(2)17(3)30-36-26/h6-9,11-14,31H,4-5,10,15H2,1-3H3,(H2,28,33)	KSOOVOZETWHNBV-UHFFFAOYSA-N	50125357	2-Butyl-5-chloro-3-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylic acid amide::CHEMBL417429	Endothelin-1 receptor		 415.0								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125357&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10280531	104017584		CHEMBL417429				ZINC26024609	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227325	CCCc1nc2CCCCC(=O)c2n1Cc1ccc(c(CC#N)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C31H33N5O4S/c1-4-9-29-33-26-11-6-7-12-27(37)30(26)36(29)19-22-14-15-24(23(18-22)16-17-32)25-10-5-8-13-28(25)41(38,39)35-31-20(2)21(3)34-40-31/h5,8,10,13-15,18,35H,4,6-7,9,11-12,16,19H2,1-3H3	PPKYHFHFSZRMQF-UHFFFAOYSA-N	50125354	2'-Cyanomethyl-4'-(8-oxo-2-propyl-5,6,7,8-tetrahydro-4H-cycloheptaimidazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL12144	Endothelin-1 receptor		 15								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125354&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44267862	104017581		CHEMBL12144				ZINC26028302	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227328	CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(c(CC)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H35N5O4S/c1-6-11-26-31-24(8-3)27(28(30)35)34(26)17-20-14-15-22(21(7-2)16-20)23-12-9-10-13-25(23)39(36,37)33-29-18(4)19(5)32-38-29/h9-10,12-16,33H,6-8,11,17H2,1-5H3,(H2,30,35)	FREUSOYKQUIGQQ-UHFFFAOYSA-N	50125362	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-2-ethyl-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid amide::CHEMBL12233	Endothelin-1 receptor		 7								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125362&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22574723	104017589		CHEMBL12233				ZINC36238176	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227331	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C36H45N5O5S/c1-6-7-14-31-37-36(17-10-11-18-36)34(43)41(31)22-26-15-16-28(27(21-26)23-40-20-19-35(4,5)33(40)42)29-12-8-9-13-30(29)47(44,45)39-32-24(2)25(3)38-46-32/h8-9,12-13,15-16,21,39H,6-7,10-11,14,17-20,22-23H2,1-5H3	NBDFXMDYBLSGLX-UHFFFAOYSA-N	50117910	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2''-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2'-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::BMS-248360::CHEMBL11706	Endothelin-1 receptor		 2								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117910&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895957	104011318		CHEMBL11706				ZINC26026608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50227332	CCCc1nc(CC)c(C(=O)NC)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C28H33N5O4S/c1-6-10-25-30-23(7-2)26(27(34)29-5)33(25)17-20-13-15-21(16-14-20)22-11-8-9-12-24(22)38(35,36)32-28-18(3)19(4)31-37-28/h8-9,11-16,32H,6-7,10,17H2,1-5H3,(H,29,34)	HXVNENCEVFFGED-UHFFFAOYSA-N	50125344	3-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-biphenyl-4-ylmethyl]-5-ethyl-2-propyl-3H-imidazole-4-carboxylic acid methylamide::CHEMBL275523	Endothelin-1 receptor		 16								ChEMBL	10.1016/s0960-894x(03)00018-0	10.7270/Q2NG4PZP	12643919			Tellew, JE; Baska, RA; Beyer, SM; Carlson, KE; Cornelius, LA; Fadnis, L; Gu, Z; Kunst, BL; Kowala, MC; Monshizadegan, H; Murugesan, N; Ryan, CS; Valentine, MT; Yang, Y; Macor, JE	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125344&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44267893	104017571		CHEMBL275523				ZINC36238168	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259839	CCC(CO)Cc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C31H36N2O6/c1-5-18(15-34)12-20-13-21(37-4)7-8-22(20)28-29(31(35)36)27(19-6-10-24-25(14-19)39-16-38-24)23-9-11-26(32-17(2)3)33-30(23)28/h6-11,13-14,17-18,27-29,34H,5,12,15-16H2,1-4H3,(H,32,33)(H,35,36)/t18?,27-,28-,29+/m0/s1	CICVRMZHTUTILV-NBNHAXFZSA-N	50141458	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxymethyl-butyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL411925	Endothelin-1 receptor			 0.011000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141458&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284287	104030917		CHEMBL411925				ZINC29252205	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259840	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CCC(C)(C)O)c1	InChI=1S/C31H36N2O6/c1-17(2)32-25-11-9-22-26(19-6-10-23-24(15-19)39-16-38-23)28(30(34)35)27(29(22)33-25)21-8-7-20(37-5)14-18(21)12-13-31(3,4)36/h6-11,14-15,17,26-28,36H,12-13,16H2,1-5H3,(H,32,33)(H,34,35)/t26-,27-,28+/m0/s1	YAWKZANKTNYRSZ-HZFUHODCSA-N	50141457	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy-3-methyl-butyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL37920	Endothelin-1 receptor			 0.065000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141457&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284391	104030916		CHEMBL37920				ZINC29312714	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259842	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OC(C)C)c1	InChI=1S/C29H32N2O6/c1-15(2)30-24-11-9-20-25(17-6-10-21-23(12-17)36-14-35-21)27(29(32)33)26(28(20)31-24)19-8-7-18(34-5)13-22(19)37-16(3)4/h6-13,15-16,25-27H,14H2,1-5H3,(H,30,31)(H,32,33)/t25-,26-,27+/m0/s1	GYPOJYXMDPSAQP-GMQQYTKMSA-N	50141459	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-isopropoxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL290181	Endothelin-1 receptor			 0.110000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141459&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284329	104030918		CHEMBL290181				ZINC29313174	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259845	CCCOc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C29H32N2O6/c1-5-12-35-22-14-18(34-4)7-8-19(22)26-27(29(32)33)25(17-6-10-21-23(13-17)37-15-36-21)20-9-11-24(30-16(2)3)31-28(20)26/h6-11,13-14,16,25-27H,5,12,15H2,1-4H3,(H,30,31)(H,32,33)/t25-,26-,27+/m0/s1	YPBPZJHPGUUGME-GMQQYTKMSA-N	50141462	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamino-7-(4-methoxy-2-propoxy-phenyl)-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL291247	Endothelin-1 receptor			 0.410000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141462&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284196	104030921		CHEMBL291247				ZINC29251752	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259850	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OCc2ccccc2)c1	InChI=1S/C33H32N2O6/c1-19(2)34-28-14-12-24-29(21-9-13-25-27(15-21)41-18-40-25)31(33(36)37)30(32(24)35-28)23-11-10-22(38-3)16-26(23)39-17-20-7-5-4-6-8-20/h4-16,19,29-31H,17-18H2,1-3H3,(H,34,35)(H,36,37)/t29-,30-,31+/m0/s1	PYNCHZOAMKYGTR-RWSKJCERSA-N	50141466	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-benzyloxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL287517	Endothelin-1 receptor			 0.800000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141466&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284199	104030925		CHEMBL287517				ZINC29251662	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259860	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CN(C)C(C)=O)c1	InChI=1S/C30H33N3O6/c1-16(2)31-25-11-9-22-26(18-6-10-23-24(13-18)39-15-38-23)28(30(35)36)27(29(22)32-25)21-8-7-20(37-5)12-19(21)14-33(4)17(3)34/h6-13,16,26-28H,14-15H2,1-5H3,(H,31,32)(H,35,36)/t26-,27-,28+/m0/s1	DWNNWTCEZHVDLU-HZFUHODCSA-N	50141471	(5S,6R,7R)-7-{2-[(Acetyl-methyl-amino)-methyl]-4-methoxy-phenyl}-5-benzo[1,3]dioxol-5-yl-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL37427	Endothelin-1 receptor			 0.027000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141471&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284266	104030930		CHEMBL37427				ZINC29316944	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259864	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CO)c1	InChI=1S/C27H28N2O6/c1-14(2)28-22-9-7-19-23(15-4-8-20-21(11-15)35-13-34-20)25(27(31)32)24(26(19)29-22)18-6-5-17(33-3)10-16(18)12-30/h4-11,14,23-25,30H,12-13H2,1-3H3,(H,28,29)(H,31,32)/t23-,24-,25+/m0/s1	FVNKNOUQLKAPJI-CCDWMCETSA-N	50141473	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-hydroxymethyl-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL287711	Endothelin-1 receptor			 0.062000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141473&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344914	104030932		CHEMBL287711				ZINC03949079	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259868	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OC)c1	InChI=1S/C27H28N2O6/c1-14(2)28-22-10-8-18-23(15-5-9-19-21(11-15)35-13-34-19)25(27(30)31)24(26(18)29-22)17-7-6-16(32-3)12-20(17)33-4/h5-12,14,23-25H,13H2,1-4H3,(H,28,29)(H,30,31)/t23-,24-,25+/m0/s1	YQDGZNPRSNHCNL-CCDWMCETSA-N	50141470	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2,4-dimethoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL36627	Endothelin-1 receptor			 0.047000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141470&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284328	104030929		CHEMBL36627				ZINC29318069	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259869	CCOc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C28H30N2O6/c1-5-34-21-13-17(33-4)7-8-18(21)25-26(28(31)32)24(16-6-10-20-22(12-16)36-14-35-20)19-9-11-23(29-15(2)3)30-27(19)25/h6-13,15,24-26H,5,14H2,1-4H3,(H,29,30)(H,31,32)/t24-,25-,26+/m0/s1	IGUNGSMXNZWMPG-KKUQBAQOSA-N	50141474	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-ethoxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL38000	Endothelin-1 receptor			 0.740000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141474&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284184	104030933		CHEMBL38000				ZINC29313555	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259877	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(O)c1	InChI=1S/C26H26N2O6/c1-13(2)27-21-9-7-17-22(14-4-8-19-20(10-14)34-12-33-19)24(26(30)31)23(25(17)28-21)16-6-5-15(32-3)11-18(16)29/h4-11,13,22-24,29H,12H2,1-3H3,(H,27,28)(H,30,31)/t22-,23-,24+/m0/s1	XNGPPJRUZXMHOV-KMDXXIMOSA-N	50141469	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-hydroxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL36671	Endothelin-1 receptor			 0.220000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141469&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284381	104030928		CHEMBL36671				ZINC29318030	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259878	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CCCO)c1	InChI=1S/C29H32N2O6/c1-16(2)30-24-11-9-21-25(18-6-10-22-23(14-18)37-15-36-22)27(29(33)34)26(28(21)31-24)20-8-7-19(35-3)13-17(20)5-4-12-32/h6-11,13-14,16,25-27,32H,4-5,12,15H2,1-3H3,(H,30,31)(H,33,34)/t25-,26-,27+/m0/s1	XZYQXDCTRBGYKO-GMQQYTKMSA-N	50141465	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL35984	Endothelin-1 receptor			 0.022000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141465&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284236	104030924		CHEMBL35984				ZINC29315268	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259881	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OCC(C)C)c1	InChI=1S/C30H34N2O6/c1-16(2)14-36-23-13-19(35-5)7-8-20(23)27-28(30(33)34)26(18-6-10-22-24(12-18)38-15-37-22)21-9-11-25(31-17(3)4)32-29(21)27/h6-13,16-17,26-28H,14-15H2,1-5H3,(H,31,32)(H,33,34)/t26-,27-,28+/m0/s1	JDIFCWUHBJXZLK-HZFUHODCSA-N	50141464	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-(2-isobutoxy-4-methoxy-phenyl)-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL37973	Endothelin-1 receptor			 0.860000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141464&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284183	104030923		CHEMBL37973				ZINC29314175	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259887	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CCO)c1	InChI=1S/C28H30N2O6/c1-15(2)29-23-9-7-20-24(17-4-8-21-22(13-17)36-14-35-21)26(28(32)33)25(27(20)30-23)19-6-5-18(34-3)12-16(19)10-11-31/h4-9,12-13,15,24-26,31H,10-11,14H2,1-3H3,(H,29,30)(H,32,33)/t24-,25-,26+/m0/s1	ZPWXQORYIQFGQB-KKUQBAQOSA-N	50141463	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy-ethyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL287622	Endothelin-1 receptor			 0.031000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141463&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284238	104030922		CHEMBL287622				ZINC29315460	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259888	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(C)(C)O)c1	InChI=1S/C30H34N2O6/c1-16(2)31-24-11-9-21-25(17-6-10-22-23(13-17)38-15-37-22)27(29(33)34)26(28(21)32-24)20-8-7-19(36-5)12-18(20)14-30(3,4)35/h6-13,16,25-27,35H,14-15H2,1-5H3,(H,31,32)(H,33,34)/t25-,26-,27+/m0/s1	GJLMSZJTTPBCHM-GMQQYTKMSA-N	50141475	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL432856	Endothelin-1 receptor			 0.014000							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141475&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284292	104030934		CHEMBL432856				ZINC29315886	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269144	CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(O)=O	InChI=1S/C22H26N2O6/c1-14(2)19(24-22(29)30-13-16-6-4-3-5-7-16)20(26)23-18(21(27)28)12-15-8-10-17(25)11-9-15/h3-11,14,18-19,25H,12-13H2,1-2H3,(H,23,26)(H,24,29)(H,27,28)	YPLGNDYBRBVBCT-UHFFFAOYSA-N	50146607	2-(2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(4-hydroxy-phenyl)-propionic acid::CHEMBL175916	Endothelin-1 receptor			 220							ChEMBL	10.1021/jm031041j	10.7270/Q26T0M3J	15139753			Funk, OF; Kettmann, V; Drimal, J; Langer, T	University of Innsbruck	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146607&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			2802888	104035196		CHEMBL175916				ZINC04321886	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269163	COC(=O)c1cc(oc1C)S(=O)(=O)Nc1cccc(c1)-c1cnco1	InChI=1S/C16H14N2O6S/c1-10-13(16(19)22-2)7-15(24-10)25(20,21)18-12-5-3-4-11(6-12)14-8-17-9-23-14/h3-9,18H,1-2H3	YMTPXZMGOFDKES-UHFFFAOYSA-N	50146614	2-Methyl-5-(3-oxazol-5-yl-phenylsulfamoyl)-furan-3-carboxylic acid methyl ester::CHEMBL367093	Endothelin-1 receptor			 6.2							ChEMBL	10.1021/jm031041j	10.7270/Q26T0M3J	15139753			Funk, OF; Kettmann, V; Drimal, J; Langer, T	University of Innsbruck	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146614&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			2809510	104035203		CHEMBL367093				ZINC01028461	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269214	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2F)cc1	InChI=1S/C31H29FN4O5/c1-19-16-20(2)35-30(34-19)41-28(29(38)39)31(23-8-4-6-10-25(23)32)24-9-5-7-11-26(24)36(27(37)17-33-31)18-21-12-14-22(40-3)15-13-21/h4-16,28,33H,17-18H2,1-3H3,(H,38,39)/t28-,31+/m1/s1	WCPSMXYWDQGMJD-MVSFAKPFSA-N	50146644	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(R)-5-(2-fluoro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL431460	Endothelin-1 receptor			 30.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146644&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11398818	104035233		CHEMBL431460				ZINC26670983	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269215	CN(C)CCN1c2ccccc2[C@](NCC1=O)([C@H](Oc1nc(C)cc(C)n1)C(O)=O)c1ccccc1	InChI=1S/C27H31N5O4/c1-18-16-19(2)30-26(29-18)36-24(25(34)35)27(20-10-6-5-7-11-20)21-12-8-9-13-22(21)32(15-14-31(3)4)23(33)17-28-27/h5-13,16,24,28H,14-15,17H2,1-4H3,(H,34,35)/t24-,27+/m1/s1	ARRVINKHLMOECL-SQHAQQRYSA-N	50146645	(S)-[(S)-1-(2-Dimethylamino-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL450628	Endothelin-1 receptor			 387.0							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146645&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11752174	104035234		CHEMBL450628				ZINC13561040	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269218	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CCc3ccccc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H30N4O4/c1-21-19-22(2)34-30(33-21)39-28(29(37)38)31(24-13-7-4-8-14-24)25-15-9-10-16-26(25)35(27(36)20-32-31)18-17-23-11-5-3-6-12-23/h3-16,19,28,32H,17-18,20H2,1-2H3,(H,37,38)/t28-,31+/m1/s1	JQAHCXASBUTBKC-MVSFAKPFSA-N	50146651	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-2-oxo-1-phenethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL96171	Endothelin-1 receptor			 3.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146651&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11489318	104035240		CHEMBL96171				ZINC13561046	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269220	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cc(F)c(F)cc3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H25F3N4O4/c1-17-12-18(2)36-29(35-17)41-27(28(39)40)30(20-8-4-3-5-9-20)21-10-6-7-11-25(21)37(26(38)15-34-30)16-19-13-23(32)24(33)14-22(19)31/h3-14,27,34H,15-16H2,1-2H3,(H,39,40)/t27-,30+/m1/s1	GEAANMFRDZRIIE-OFSOJUDTSA-N	50146646	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,5-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL419879	Endothelin-1 receptor			 7.2							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146646&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11478553	104035235		CHEMBL419879				ZINC26673566	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269224	CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1nc(C)cc(C)n1)C(O)=O)c1ccccc1	InChI=1S/C24H24N4O4/c1-15-13-16(2)27-23(26-15)32-21(22(30)31)24(17-9-5-4-6-10-17)18-11-7-8-12-19(18)28(3)20(29)14-25-24/h4-13,21,25H,14H2,1-3H3,(H,30,31)/t21-,24+/m1/s1	FINMPMBYTTVLPJ-QPPBQGQZSA-N	50146654	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL330425	Endothelin-1 receptor			 12.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146654&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10224745	104035243		CHEMBL330425				ZINC13561023	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269226	COc1cc(OC)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccc(Cl)cc23)c2ccccc2)c1	InChI=1S/C26H25ClN2O6/c1-29-22-10-9-17(27)11-21(22)26(28-15-23(29)30,16-7-5-4-6-8-16)24(25(31)32)35-20-13-18(33-2)12-19(14-20)34-3/h4-14,24,28H,15H2,1-3H3,(H,31,32)/t24-,26+/m1/s1	VGSKFGCGPLNHJZ-RSXGOPAZSA-N	50146658	(S)-((S)-7-Chloro-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid::CHEMBL96125	Endothelin-1 receptor			 262							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146658&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11397857	104035247		CHEMBL96125				ZINC13561018	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269229	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cccc(F)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27FN4O4/c1-19-15-20(2)34-29(33-19)39-27(28(37)38)30(22-10-4-3-5-11-22)24-13-6-7-14-25(24)35(26(36)17-32-30)18-21-9-8-12-23(31)16-21/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	SEXZWLMIBXVFQM-OFSOJUDTSA-N	50146655	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(3-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96746	Endothelin-1 receptor			 6.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146655&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11375934	104035244		CHEMBL96746				ZINC26671672	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269230	Cc1cccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)c1	InChI=1S/C31H30N4O4/c1-20-10-9-11-23(16-20)19-35-26-15-8-7-14-25(26)31(32-18-27(35)36,24-12-5-4-6-13-24)28(29(37)38)39-30-33-21(2)17-22(3)34-30/h4-17,28,32H,18-19H2,1-3H3,(H,37,38)/t28-,31+/m1/s1	LZMBWESXCWUQBJ-MVSFAKPFSA-N	50146659	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(3-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL94212	Endothelin-1 receptor			 5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146659&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11318409	104035248		CHEMBL94212				ZINC13561048	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269231	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(F)cc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27FN4O4/c1-19-16-20(2)34-29(33-19)39-27(28(37)38)30(22-8-4-3-5-9-22)24-10-6-7-11-25(24)35(26(36)17-32-30)18-21-12-14-23(31)15-13-21/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	BKUCZUUARYQRPP-OFSOJUDTSA-N	50146660	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL314755	Endothelin-1 receptor			 5.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146660&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11785813	104035249		CHEMBL314755				ZINC26673563	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269232	COC(=O)c1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)cc1	InChI=1S/C32H30N4O6/c1-20-17-21(2)35-31(34-20)42-28(29(38)39)32(24-9-5-4-6-10-24)25-11-7-8-12-26(25)36(27(37)18-33-32)19-22-13-15-23(16-14-22)30(40)41-3/h4-17,28,33H,18-19H2,1-3H3,(H,38,39)/t28-,32+/m1/s1	MHZFPYMEACEGKL-NSJVFKKDSA-N	50146661	4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid methyl ester::CHEMBL316301	Endothelin-1 receptor			 7.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146661&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10303311	104035250		CHEMBL316301				ZINC26675490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269233	COc1cc(OC)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccccc23)c2ccccc2)n1	InChI=1S/C24H24N4O6/c1-28-17-12-8-7-11-16(17)24(25-14-20(28)29,15-9-5-4-6-10-15)21(22(30)31)34-23-26-18(32-2)13-19(27-23)33-3/h4-13,21,25H,14H2,1-3H3,(H,30,31)/t21-,24+/m1/s1	IGKCOJUPPUGBIE-QPPBQGQZSA-N	50146662	(S)-(4,6-Dimethoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL96906	Endothelin-1 receptor			 23.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146662&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11408654	104035251		CHEMBL96906				ZINC13561024	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269234	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(Br)cc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27BrN4O4/c1-19-16-20(2)34-29(33-19)39-27(28(37)38)30(22-8-4-3-5-9-22)24-10-6-7-11-25(24)35(26(36)17-32-30)18-21-12-14-23(31)15-13-21/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	BZSLFEJGVQKVKX-OFSOJUDTSA-N	50146663	(S)-[(S)-1-(4-Bromo-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL94962	Endothelin-1 receptor			 25.8							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146663&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11753582	104035252		CHEMBL94962				ZINC26671356	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269236	CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1ncccn1)C(O)=O)c1ccccc1	InChI=1S/C22H20N4O4/c1-26-17-11-6-5-10-16(17)22(25-14-18(26)27,15-8-3-2-4-9-15)19(20(28)29)30-21-23-12-7-13-24-21/h2-13,19,25H,14H2,1H3,(H,28,29)/t19-,22+/m1/s1	AJPNEAQSWFQACP-KNQAVFIVSA-N	50146668	(S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(pyrimidin-2-yloxy)-acetic acid::CHEMBL92612	Endothelin-1 receptor			 1570							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146668&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11452452	104035257		CHEMBL92612				ZINC13561022	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269239	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)cccc3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26F2N4O4/c1-18-15-19(2)35-29(34-18)40-27(28(38)39)30(20-9-4-3-5-10-20)22-11-6-7-14-25(22)36(26(37)16-33-30)17-21-23(31)12-8-13-24(21)32/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	JHOHFSMURHXTHA-OFSOJUDTSA-N	50146652	(S)-[(S)-1-(2,6-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL329251	Endothelin-1 receptor			 1.1							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146652&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10230737	104035241		CHEMBL329251				ZINC26667645	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269243	Cc1nnc2CN[C@@]([C@H](Oc3nc(C)cc(C)n3)C(O)=O)(c3ccccc3)c3ccccc3-n12	InChI=1S/C25H24N6O3/c1-15-13-16(2)28-24(27-15)34-22(23(32)33)25(18-9-5-4-6-10-18)19-11-7-8-12-20(19)31-17(3)29-30-21(31)14-26-25/h4-13,22,26H,14H2,1-3H3,(H,32,33)/t22-,25+/m1/s1	XMLFZKYJSPXNGH-RDGATRHJSA-N	50146671	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulen-6-yl)-acetic acid::CHEMBL96614	Endothelin-1 receptor			 55.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146671&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10226239	104035260		CHEMBL96614				ZINC13561033	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269245	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CCC3CCCCC3)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H36N4O4/c1-21-19-22(2)34-30(33-21)39-28(29(37)38)31(24-13-7-4-8-14-24)25-15-9-10-16-26(25)35(27(36)20-32-31)18-17-23-11-5-3-6-12-23/h4,7-10,13-16,19,23,28,32H,3,5-6,11-12,17-18,20H2,1-2H3,(H,37,38)/t28-,31+/m1/s1	ZMUVTNWMWOXWGB-MVSFAKPFSA-N	50146672	(S)-[(S)-1-(2-Cyclohexyl-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL94752	Endothelin-1 receptor			 146							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146672&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11386977	104035261		CHEMBL94752				ZINC13561038	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269247	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccccc3C)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H30N4O4/c1-20-11-7-8-12-23(20)19-35-26-16-10-9-15-25(26)31(32-18-27(35)36,24-13-5-4-6-14-24)28(29(37)38)39-30-33-21(2)17-22(3)34-30/h4-17,28,32H,18-19H2,1-3H3,(H,37,38)/t28-,31+/m1/s1	ITICTHRGYDERJA-MVSFAKPFSA-N	50146666	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL314946	Endothelin-1 receptor			 8.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146666&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11432418	104035255		CHEMBL314946				ZINC13561047	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269254	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CC3CCCCC3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H34N4O4/c1-20-17-21(2)33-29(32-20)38-27(28(36)37)30(23-13-7-4-8-14-23)24-15-9-10-16-25(24)34(26(35)18-31-30)19-22-11-5-3-6-12-22/h4,7-10,13-17,22,27,31H,3,5-6,11-12,18-19H2,1-2H3,(H,36,37)/t27-,30+/m1/s1	YTNUBEUYCFIHBS-OFSOJUDTSA-N	50146680	(S)-((S)-1-Cyclohexylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL329943	Endothelin-1 receptor			 83.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146680&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11489174	104035269		CHEMBL329943				ZINC13561037	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269256	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(cc3)C(C)(C)C)c3ccccc23)c2ccccc2)n1	InChI=1S/C34H36N4O4/c1-22-19-23(2)37-32(36-22)42-30(31(40)41)34(26-11-7-6-8-12-26)27-13-9-10-14-28(27)38(29(39)20-35-34)21-24-15-17-25(18-16-24)33(3,4)5/h6-19,30,35H,20-21H2,1-5H3,(H,40,41)/t30-,34+/m1/s1	GEKLWHMKKGCLLE-HKFHRXRESA-N	50146681	(S)-[(S)-1-(4-tert-Butyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL96154	Endothelin-1 receptor			 17.1							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146681&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11365059	104035270		CHEMBL96154				ZINC26667487	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269257	Cc1cc(C)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)c1	InChI=1S/C32H28Cl2N2O4/c1-20-15-21(2)17-23(16-20)40-30(31(38)39)32(22-9-4-3-5-10-22)25-11-6-7-14-28(25)36(29(37)18-35-32)19-24-26(33)12-8-13-27(24)34/h3-17,30,35H,18-19H2,1-2H3,(H,38,39)/t30-,32+/m1/s1	NHVWTLKWIKMKNS-BHYZAODMSA-N	50146678	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethyl-phenoxy)-acetic acid::CHEMBL94802	Endothelin-1 receptor			 20.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146678&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11169125	104035267		CHEMBL94802					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269266	CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1ncc(Br)cn1)C(O)=O)c1ccccc1	InChI=1S/C22H19BrN4O4/c1-27-17-10-6-5-9-16(17)22(26-13-18(27)28,14-7-3-2-4-8-14)19(20(29)30)31-21-24-11-15(23)12-25-21/h2-12,19,26H,13H2,1H3,(H,29,30)/t19-,22+/m1/s1	QVGXUVBAAYSIBS-KNQAVFIVSA-N	50146689	(S)-(5-Bromo-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL96520	Endothelin-1 receptor			 927.0							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146689&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11488556	104035278		CHEMBL96520				ZINC13561028	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269267	Cc1cc(C)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)cccc3Cl)c3ccccc23)c2ccccc2)c1	InChI=1S/C32H28ClFN2O4/c1-20-15-21(2)17-23(16-20)40-30(31(38)39)32(22-9-4-3-5-10-22)25-11-6-7-14-28(25)36(29(37)18-35-32)19-24-26(33)12-8-13-27(24)34/h3-17,30,35H,18-19H2,1-2H3,(H,38,39)/t30-,32+/m1/s1	GQTAIGFWINAVHA-BHYZAODMSA-N	50146692	(S)-[(S)-1-(2-Chloro-6-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethyl-phenoxy)-acetic acid::CHEMBL96704	Endothelin-1 receptor			 18.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146692&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11226740	104035281		CHEMBL96704				ZINC26670558	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269272	Cc1cccc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)c1C	InChI=1S/C32H28Cl2N2O4/c1-20-10-8-17-28(21(20)2)40-30(31(38)39)32(22-11-4-3-5-12-22)24-13-6-7-16-27(24)36(29(37)18-35-32)19-23-25(33)14-9-15-26(23)34/h3-17,30,35H,18-19H2,1-2H3,(H,38,39)/t30-,32+/m1/s1	KHUZXZGGNVVKJR-BHYZAODMSA-N	50146693	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,3-dimethyl-phenoxy)-acetic acid::CHEMBL94370	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146693&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11192437	104035282		CHEMBL94370				ZINC26674986	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269273	COc1cc(OC)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3cc(Cl)ccc23)c2ccccc2)c1	InChI=1S/C26H25ClN2O6/c1-29-22-11-17(27)9-10-21(22)26(28-15-23(29)30,16-7-5-4-6-8-16)24(25(31)32)35-20-13-18(33-2)12-19(14-20)34-3/h4-14,24,28H,15H2,1-3H3,(H,31,32)/t24-,26+/m1/s1	PPOOJIQTAPLDLF-RSXGOPAZSA-N	50146694	(S)-((S)-8-Chloro-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid::CHEMBL96351	Endothelin-1 receptor			 3840							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146694&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11167889	104035283		CHEMBL96351				ZINC13561019	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269274	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccccc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H28N4O4/c1-20-17-21(2)33-29(32-20)38-27(28(36)37)30(23-13-7-4-8-14-23)24-15-9-10-16-25(24)34(26(35)18-31-30)19-22-11-5-3-6-12-22/h3-17,27,31H,18-19H2,1-2H3,(H,36,37)/t27-,30+/m1/s1	LZPJHRAWMATYTH-OFSOJUDTSA-N	50146695	(S)-((S)-1-Benzyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL95013	Endothelin-1 receptor			 6.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146695&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11283571	104035284		CHEMBL95013				ZINC13561045	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269275	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cccc(c3)C(F)(F)F)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H27F3N4O4/c1-19-15-20(2)37-29(36-19)42-27(28(40)41)30(22-10-4-3-5-11-22)24-13-6-7-14-25(24)38(26(39)17-35-30)18-21-9-8-12-23(16-21)31(32,33)34/h3-16,27,35H,17-18H2,1-2H3,(H,40,41)/t27-,30+/m1/s1	SQHUBOCKWBVIDO-OFSOJUDTSA-N	50146687	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL319007	Endothelin-1 receptor			 9.1							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146687&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11376627	104035276		CHEMBL319007				ZINC26668775	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269278	CCc1cccc(c1)[C@@]1(NCC(=O)N(Cc2ccc(OC)cc2)c2ccccc12)[C@H](Oc1nc(C)cc(C)n1)C(O)=O	InChI=1S/C33H34N4O5/c1-5-23-9-8-10-25(18-23)33(30(31(39)40)42-32-35-21(2)17-22(3)36-32)27-11-6-7-12-28(27)37(29(38)19-34-33)20-24-13-15-26(41-4)16-14-24/h6-18,30,34H,5,19-20H2,1-4H3,(H,39,40)/t30-,33+/m1/s1	FJHPXCQTPSEFDQ-NDKRRWIDSA-N	50146700	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(3-ethyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96932	Endothelin-1 receptor			 3.1							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146700&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11353580	104035289		CHEMBL96932				ZINC26672957	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269281	OC(=O)[C@@H](Oc1ccccc1)[C@]1(NCC(=O)N(Cc2c(Cl)cccc2Cl)c2ccccc12)c1ccccc1	InChI=1S/C30H24Cl2N2O4/c31-24-15-9-16-25(32)22(24)19-34-26-17-8-7-14-23(26)30(33-18-27(34)35,20-10-3-1-4-11-20)28(29(36)37)38-21-12-5-2-6-13-21/h1-17,28,33H,18-19H2,(H,36,37)/t28-,30+/m1/s1	KTLNHNBNFFGGQC-DGPALRBDSA-N	50146705	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-phenoxy-acetic acid::CHEMBL440507	Endothelin-1 receptor			 211							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146705&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11786120	104035294		CHEMBL440507				ZINC26666885	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269282	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccccc3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27FN4O4/c1-19-16-20(2)34-29(33-19)39-27(28(37)38)30(22-11-4-3-5-12-22)23-13-7-9-15-25(23)35(26(36)17-32-30)18-21-10-6-8-14-24(21)31/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	LFVLYJPEMPWXGS-OFSOJUDTSA-N	50146702	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96723	Endothelin-1 receptor			 3.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146702&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11168474	104035291		CHEMBL96723				ZINC26672606	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269283	CCCCc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)cc1	InChI=1S/C34H36N4O4/c1-4-5-11-25-16-18-26(19-17-25)22-38-29-15-10-9-14-28(29)34(35-21-30(38)39,27-12-7-6-8-13-27)31(32(40)41)42-33-36-23(2)20-24(3)37-33/h6-10,12-20,31,35H,4-5,11,21-22H2,1-3H3,(H,40,41)/t31-,34+/m1/s1	LTFMLNPARFSYNA-FJQKOURKSA-N	50146704	(S)-[(S)-1-(4-Butyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL415010	Endothelin-1 receptor			 3.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146704&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10303258	104035293		CHEMBL415010				ZINC26666387	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269285	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cc(C)cc(C)c2)cc1	InChI=1S/C33H34N4O5/c1-20-14-21(2)16-25(15-20)33(30(31(39)40)42-32-35-22(3)17-23(4)36-32)27-8-6-7-9-28(27)37(29(38)18-34-33)19-24-10-12-26(41-5)13-11-24/h6-17,30,34H,18-19H2,1-5H3,(H,39,40)/t30-,33+/m1/s1	YQOHFDDJNGNMBZ-NDKRRWIDSA-N	50146667	(S)-[(S)-5-(3,5-Dimethyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL93612	Endothelin-1 receptor			 278.0							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146667&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11489946	104035256		CHEMBL93612				ZINC26675255	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269286	COC([C@H](Oc1nc(C)cc(C)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1	OUJTZYPIHDYQMC-LJQANCHMSA-N	50146710	(S)-2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::AMBRISENTAN::CHEMBL1111::Letairis	Endothelin-1 receptor			 21.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146710&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918493	104035299		CHEMBL1111		3951		ZINC00538627	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269287	COc1cccc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)c1	InChI=1S/C31H26Cl2N2O5/c1-39-21-11-7-12-22(17-21)40-29(30(37)38)31(20-9-3-2-4-10-20)24-13-5-6-16-27(24)35(28(36)18-34-31)19-23-25(32)14-8-15-26(23)33/h2-17,29,34H,18-19H2,1H3,(H,37,38)/t29-,31+/m1/s1	NXJHZQRDQFTXEZ-VEEOACQBSA-N	50146691	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3-methoxy-phenoxy)-acetic acid::CHEMBL94602	Endothelin-1 receptor			 129							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146691&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11238540	104035280		CHEMBL94602				ZINC26671612	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269291	CCc1cc(CC)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccccc23)c2ccccc2)n1	InChI=1S/C26H28N4O4/c1-4-18-15-19(5-2)29-25(28-18)34-23(24(32)33)26(17-11-7-6-8-12-17)20-13-9-10-14-21(20)30(3)22(31)16-27-26/h6-15,23,27H,4-5,16H2,1-3H3,(H,32,33)/t23-,26+/m1/s1	TVTJICVMTXUAKS-BVAGGSTKSA-N	50146707	(S)-(4,6-Diethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL318270	Endothelin-1 receptor			 20.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146707&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11224973	104035296		CHEMBL318270				ZINC13561025	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269292	Cc1cc(C)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)cc(F)cc3F)c3ccccc23)c2ccccc2)c1	InChI=1S/C32H27F3N2O4/c1-19-12-20(2)14-23(13-19)41-30(31(39)40)32(21-8-4-3-5-9-21)25-10-6-7-11-28(25)37(29(38)17-36-32)18-24-26(34)15-22(33)16-27(24)35/h3-16,30,36H,17-18H2,1-2H3,(H,39,40)/t30-,32+/m1/s1	SDXSGUVLSFVWRF-BHYZAODMSA-N	50146706	(S)-(3,5-Dimethyl-phenoxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96347	Endothelin-1 receptor			 17.2							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146706&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347783	104035295		CHEMBL96347				ZINC55865623	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269295	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cccc(OC(F)(F)F)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H27F3N4O5/c1-19-15-20(2)37-29(36-19)42-27(28(40)41)30(22-10-4-3-5-11-22)24-13-6-7-14-25(24)38(26(39)17-35-30)18-21-9-8-12-23(16-21)43-31(32,33)34/h3-16,27,35H,17-18H2,1-2H3,(H,40,41)/t27-,30+/m1/s1	MZAAFBAXCKYSNN-OFSOJUDTSA-N	50146670	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96422	Endothelin-1 receptor			 11							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146670&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11421972	104035259		CHEMBL96422				ZINC26670570	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269296	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccccc3Cl)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27ClN4O4/c1-19-16-20(2)34-29(33-19)39-27(28(37)38)30(22-11-4-3-5-12-22)23-13-7-9-15-25(23)35(26(36)17-32-30)18-21-10-6-8-14-24(21)31/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	QCHYZDXDWZKACW-OFSOJUDTSA-N	50146711	(S)-[(S)-1-(2-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL96472	Endothelin-1 receptor			 10.2							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146711&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10230703	104035300		CHEMBL96472				ZINC26667884	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269297	OC(=O)[C@@H](Oc1ccccc1Cl)[C@]1(NCC(=O)N(Cc2c(Cl)cccc2Cl)c2ccccc12)c1ccccc1	InChI=1S/C30H23Cl3N2O4/c31-22-13-8-14-23(32)20(22)18-35-25-15-6-4-11-21(25)30(34-17-27(35)36,19-9-2-1-3-10-19)28(29(37)38)39-26-16-7-5-12-24(26)33/h1-16,28,34H,17-18H2,(H,37,38)/t28-,30+/m1/s1	IVWIQIFWYAYEJU-DGPALRBDSA-N	50146684	(S)-(2-Chloro-phenoxy)-[(S)-1-(2,6-dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL419148	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146684&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11192508	104035273		CHEMBL419148					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269298	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(F)c(F)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26F2N4O4/c1-18-14-19(2)35-29(34-18)40-27(28(38)39)30(21-8-4-3-5-9-21)22-10-6-7-11-25(22)36(26(37)16-33-30)17-20-12-13-23(31)24(32)15-20/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	HTKNCJNRSZJTJH-OFSOJUDTSA-N	50146696	(S)-[(S)-1-(3,4-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL420435	Endothelin-1 receptor			 6.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146696&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11364770	104035285		CHEMBL420435				ZINC26663277	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269299	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(F)c(F)c3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H25F3N4O4/c1-17-14-18(2)36-29(35-17)41-27(28(39)40)30(20-8-4-3-5-9-20)21-10-6-7-11-23(21)37(24(38)15-34-30)16-19-12-13-22(31)26(33)25(19)32/h3-14,27,34H,15-16H2,1-2H3,(H,39,40)/t27-,30+/m1/s1	FYPZYGLVQHCNCC-OFSOJUDTSA-N	50146716	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,3,4-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL93084	Endothelin-1 receptor			 6.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146716&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10209814	104035305		CHEMBL93084				ZINC26663270	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269301	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)cccc3Cl)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26ClFN4O4/c1-18-15-19(2)35-29(34-18)40-27(28(38)39)30(20-9-4-3-5-10-20)22-11-6-7-14-25(22)36(26(37)16-33-30)17-21-23(31)12-8-13-24(21)32/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	OXPNVLRJIHCUBM-OFSOJUDTSA-N	50146717	(S)-[(S)-1-(2-Chloro-6-fluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL431286	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146717&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11318978	104035306		CHEMBL431286				ZINC26674845	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269304	CC(C)c1ccc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)cc1	InChI=1S/C33H30Cl2N2O4/c1-21(2)22-15-17-24(18-16-22)41-31(32(39)40)33(23-9-4-3-5-10-23)26-11-6-7-14-29(26)37(30(38)19-36-33)20-25-27(34)12-8-13-28(25)35/h3-18,21,31,36H,19-20H2,1-2H3,(H,39,40)/t31-,33+/m1/s1	ZSKGACAIGPYCKP-VTIYRKAUSA-N	50146726	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4-isopropyl-phenoxy)-acetic acid::CHEMBL420072	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146726&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11157599	104035315		CHEMBL420072					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269306	COc1cc(OC)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccccc23)c2ccccc2)c1	InChI=1S/C26H26N2O6/c1-28-22-12-8-7-11-21(22)26(27-16-23(28)29,17-9-5-4-6-10-17)24(25(30)31)34-20-14-18(32-2)13-19(15-20)33-3/h4-15,24,27H,16H2,1-3H3,(H,30,31)/t24-,26+/m1/s1	TVZNWRRDEJEANN-RSXGOPAZSA-N	50146698	(S)-(3,5-Dimethoxy-phenoxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL330629	Endothelin-1 receptor			 605							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146698&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11385689	104035287		CHEMBL330629				ZINC13561017	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269307	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cccc(Br)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27BrN4O4/c1-19-15-20(2)34-29(33-19)39-27(28(37)38)30(22-10-4-3-5-11-22)24-13-6-7-14-25(24)35(26(36)17-32-30)18-21-9-8-12-23(31)16-21/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	MNJJBWIQROUNDM-OFSOJUDTSA-N	50146727	(S)-[(S)-1-(3-Bromo-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL317589	Endothelin-1 receptor			 6.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146727&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11307805	104035316		CHEMBL317589				ZINC26673705	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269309	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cccc(F)c3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26F2N4O4/c1-18-15-19(2)35-29(34-18)40-27(28(38)39)30(21-10-4-3-5-11-21)22-12-6-7-14-24(22)36(25(37)16-33-30)17-20-9-8-13-23(31)26(20)32/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	RQKVNFYBHIQIDV-OFSOJUDTSA-N	50146713	(S)-[(S)-1-(2,3-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL93820	Endothelin-1 receptor			 3.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146713&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11421392	104035302		CHEMBL93820				ZINC26675249	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269312	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(cc3)-c3ccccc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C36H32N4O4/c1-24-21-25(2)39-35(38-24)44-33(34(42)43)36(29-13-7-4-8-14-29)30-15-9-10-16-31(30)40(32(41)22-37-36)23-26-17-19-28(20-18-26)27-11-5-3-6-12-27/h3-21,33,37H,22-23H2,1-2H3,(H,42,43)/t33-,36+/m1/s1	GBYVJKRBUNPVLB-ILFWFZRHSA-N	50146649	(S)-((S)-1-Biphenyl-4-ylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL94446	Endothelin-1 receptor			 102							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146649&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11490160	104035238		CHEMBL94446				ZINC26671093	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269313	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccccc3C(F)(F)F)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H27F3N4O4/c1-19-16-20(2)37-29(36-19)42-27(28(40)41)30(22-11-4-3-5-12-22)24-14-8-9-15-25(24)38(26(39)17-35-30)18-21-10-6-7-13-23(21)31(32,33)34/h3-16,27,35H,17-18H2,1-2H3,(H,40,41)/t27-,30+/m1/s1	QSPLUDJQEFUAHB-OFSOJUDTSA-N	50146722	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96506	Endothelin-1 receptor			 104							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146722&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11273181	104035311		CHEMBL96506				ZINC26671680	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269314	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccccc3OC(F)(F)F)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H27F3N4O5/c1-19-16-20(2)37-29(36-19)42-27(28(40)41)30(22-11-4-3-5-12-22)23-13-7-8-14-24(23)38(26(39)17-35-30)18-21-10-6-9-15-25(21)43-31(32,33)34/h3-16,27,35H,17-18H2,1-2H3,(H,40,41)/t27-,30+/m1/s1	KKGSEDUFHOPCFO-OFSOJUDTSA-N	50146723	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96387	Endothelin-1 receptor			 98.6							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146723&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11456110	104035312		CHEMBL96387				ZINC26671676	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269315	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2cccc(c2)-c2ccccc2)n1	InChI=1S/C36H30Cl2N4O4/c1-22-18-23(2)41-35(40-22)46-33(34(44)45)36(26-13-8-12-25(19-26)24-10-4-3-5-11-24)28-14-6-7-17-31(28)42(32(43)20-39-36)21-27-29(37)15-9-16-30(27)38/h3-19,33,39H,20-21H2,1-2H3,(H,44,45)/t33-,36+/m1/s1	FHRCXZSDINFQMI-ILFWFZRHSA-N	50146725	(S)-[(S)-5-Biphenyl-3-yl-1-(2,6-dichloro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL318086	Endothelin-1 receptor			 16.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146725&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11331242	104035314		CHEMBL318086				ZINC26668583	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269319	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(OC(F)(F)F)cc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H27F3N4O5/c1-19-16-20(2)37-29(36-19)42-27(28(40)41)30(22-8-4-3-5-9-22)24-10-6-7-11-25(24)38(26(39)17-35-30)18-21-12-14-23(15-13-21)43-31(32,33)34/h3-16,27,35H,17-18H2,1-2H3,(H,40,41)/t27-,30+/m1/s1	MHHROYOBQSBUEV-OFSOJUDTSA-N	50146730	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(4-trifluoromethoxy-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL91873	Endothelin-1 receptor			 2.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146730	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146730&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10282008	104035319		CHEMBL91873				ZINC26665871	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269324	Cc1cc(C)c(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)c(C)c1	InChI=1S/C33H34N4O4/c1-20-15-21(2)26(22(3)16-20)19-37-28-14-10-9-13-27(28)33(34-18-29(37)38,25-11-7-6-8-12-25)30(31(39)40)41-32-35-23(4)17-24(5)36-32/h6-17,30,34H,18-19H2,1-5H3,(H,39,40)/t30-,33+/m1/s1	YFGVPMLVIXUCGP-NDKRRWIDSA-N	50146719	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trimethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL419136	Endothelin-1 receptor			 6.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146719&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10166139	104035308		CHEMBL419136				ZINC26665496	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269325	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccc(C)cc2)cc1	InChI=1S/C32H32N4O5/c1-20-9-13-24(14-10-20)32(29(30(38)39)41-31-34-21(2)17-22(3)35-31)26-7-5-6-8-27(26)36(28(37)18-33-32)19-23-11-15-25(40-4)16-12-23/h5-17,29,33H,18-19H2,1-4H3,(H,38,39)/t29-,32+/m1/s1	FVWWHXXCNJDXHS-PPTMTGTBSA-N	50146724	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-p-tolyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL94091	Endothelin-1 receptor			 221							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146724&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11387315	104035313		CHEMBL94091				ZINC26671951	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269327	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(F)cc3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26F2N4O4/c1-18-14-19(2)35-29(34-18)40-27(28(38)39)30(21-8-4-3-5-9-21)23-10-6-7-11-25(23)36(26(37)16-33-30)17-20-12-13-22(31)15-24(20)32/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	YCVDVWIZRUNCFR-OFSOJUDTSA-N	50146656	(S)-[(S)-1-(2,4-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL318247	Endothelin-1 receptor			 6							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146656&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10187313	104035245		CHEMBL318247				ZINC26665311	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269328	Cc1ccc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)cc1	InChI=1S/C31H26Cl2N2O4/c1-20-14-16-22(17-15-20)39-29(30(37)38)31(21-8-3-2-4-9-21)24-10-5-6-13-27(24)35(28(36)18-34-31)19-23-25(32)11-7-12-26(23)33/h2-17,29,34H,18-19H2,1H3,(H,37,38)/t29-,31+/m1/s1	RLZUSDGCLWDQGG-VEEOACQBSA-N	50146653	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-p-tolyloxy-acetic acid::CHEMBL94606	Endothelin-1 receptor			 156							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146653&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11226767	104035242		CHEMBL94606				ZINC26673687	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269330	COCCOCN1c2ccccc2[C@](NCC1=O)([C@H](Oc1nc(C)cc(C)n1)C(O)=O)c1ccccc1	InChI=1S/C27H30N4O6/c1-18-15-19(2)30-26(29-18)37-24(25(33)34)27(20-9-5-4-6-10-20)21-11-7-8-12-22(21)31(23(32)16-28-27)17-36-14-13-35-3/h4-12,15,24,28H,13-14,16-17H2,1-3H3,(H,33,34)/t24-,27+/m1/s1	WLXMNQFBLVMITG-SQHAQQRYSA-N	50146709	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-methoxy-ethoxymethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL433173	Endothelin-1 receptor			 7.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146709&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11477664	104035298		CHEMBL433173				ZINC26666327	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269332	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3nnn[nH]3)c3ccccc23)c2ccccc2)n1	InChI=1S/C25H24N8O4/c1-15-12-16(2)28-24(27-15)37-22(23(35)36)25(17-8-4-3-5-9-17)18-10-6-7-11-19(18)33(21(34)13-26-25)14-20-29-31-32-30-20/h3-12,22,26H,13-14H2,1-2H3,(H,35,36)(H,29,30,31,32)/t22-,25+/m1/s1	PQGJCQZVHZMJFI-RDGATRHJSA-N	50146648	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2H-tetrazol-5-ylmethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL94964	Endothelin-1 receptor			 6.6							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146648&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10163956	104035237		CHEMBL94964				ZINC13561043	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269333	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cccc(F)c2)cc1	InChI=1S/C31H29FN4O5/c1-19-15-20(2)35-30(34-19)41-28(29(38)39)31(22-7-6-8-23(32)16-22)25-9-4-5-10-26(25)36(27(37)17-33-31)18-21-11-13-24(40-3)14-12-21/h4-16,28,33H,17-18H2,1-3H3,(H,38,39)/t28-,31+/m1/s1	KIJALYSAGLYTQO-MVSFAKPFSA-N	50146718	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(3-fluoro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL95095	Endothelin-1 receptor			 9.1							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146718&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11307457	104035307		CHEMBL95095				ZINC26670342	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269334	COc1cc(OC)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3cc(OC)c(OC)cc23)c2ccccc2)c1	InChI=1S/C28H30N2O8/c1-30-22-15-24(37-5)23(36-4)14-21(22)28(29-16-25(30)31,17-9-7-6-8-10-17)26(27(32)33)38-20-12-18(34-2)11-19(13-20)35-3/h6-15,26,29H,16H2,1-5H3,(H,32,33)/t26-,28+/m1/s1	SIDYXJUOCRCIEO-IAPPQJPRSA-N	50146697	(S)-((S)-7,8-Dimethoxy-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(3,5-dimethoxy-phenoxy)-acetic acid::CHEMBL329132	Endothelin-1 receptor			 443.0							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146697&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11168401	104035286		CHEMBL329132				ZINC13561021	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269335	COc1ccccc1O[C@H](C(O)=O)[C@]1(NCC(=O)N(Cc2c(Cl)cccc2Cl)c2ccccc12)c1ccccc1	InChI=1S/C31H26Cl2N2O5/c1-39-26-16-7-8-17-27(26)40-29(30(37)38)31(20-10-3-2-4-11-20)22-12-5-6-15-25(22)35(28(36)18-34-31)19-21-23(32)13-9-14-24(21)33/h2-17,29,34H,18-19H2,1H3,(H,37,38)/t29-,31+/m1/s1	UFFWCFPJRRIUKB-VEEOACQBSA-N	50146682	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2-methoxy-phenoxy)-acetic acid::CHEMBL314511	Endothelin-1 receptor			 5920							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146682&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11203972	104035271		CHEMBL314511				ZINC26674457	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269336	CCCCc1cccc(c1)[C@@]1(NCC(=O)N(Cc2c(F)cc(F)cc2F)c2ccccc12)[C@H](Oc1nc(C)cc(C)n1)C(O)=O	InChI=1S/C34H33F3N4O4/c1-4-5-9-22-10-8-11-23(15-22)34(31(32(43)44)45-33-39-20(2)14-21(3)40-33)26-12-6-7-13-29(26)41(30(42)18-38-34)19-25-27(36)16-24(35)17-28(25)37/h6-8,10-17,31,38H,4-5,9,18-19H2,1-3H3,(H,43,44)/t31-,34+/m1/s1	XIKMSNPORKHQQQ-FJQKOURKSA-N	50146699	(S)-[(S)-5-(3-Butyl-phenyl)-2-oxo-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL330354	Endothelin-1 receptor			 13.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146699&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11308052	104035288		CHEMBL330354					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269338	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cccc(c2)-c2ccccc2)cc1	InChI=1S/C37H34N4O5/c1-24-20-25(2)40-36(39-24)46-34(35(43)44)37(29-13-9-12-28(21-29)27-10-5-4-6-11-27)31-14-7-8-15-32(31)41(33(42)22-38-37)23-26-16-18-30(45-3)19-17-26/h4-21,34,38H,22-23H2,1-3H3,(H,43,44)/t34-,37+/m1/s1	DEYKKRWFIMYKJM-BLPFIKBVSA-N	50146734	(S)-[(S)-5-Biphenyl-3-yl-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL316453	Endothelin-1 receptor			 3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146734&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11387934	104035323		CHEMBL316453				ZINC26667324	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269341	COc1ccc2c(c1)N(C)C(=O)CN[C@@]2([C@H](Oc1cc(OC)cc(OC)c1)C(O)=O)c1ccccc1	InChI=1S/C27H28N2O7/c1-29-23-15-18(33-2)10-11-22(23)27(28-16-24(29)30,17-8-6-5-7-9-17)25(26(31)32)36-21-13-19(34-3)12-20(14-21)35-4/h5-15,25,28H,16H2,1-4H3,(H,31,32)/t25-,27+/m1/s1	QTZAGXZFDQCJKV-VPUSJEBWSA-N	50146733	(S)-(3,5-Dimethoxy-phenoxy)-((S)-8-methoxy-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL327823	Endothelin-1 receptor			 3950							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146733&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11785180	104035322		CHEMBL327823				ZINC13561020	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269343	COc1cc(OC)cc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)c1	InChI=1S/C32H28Cl2N2O6/c1-40-21-15-22(41-2)17-23(16-21)42-30(31(38)39)32(20-9-4-3-5-10-20)25-11-6-7-14-28(25)36(29(37)18-35-32)19-24-26(33)12-8-13-27(24)34/h3-17,30,35H,18-19H2,1-2H3,(H,38,39)/t30-,32+/m1/s1	JPRDUKLJMTUKCJ-BHYZAODMSA-N	50146688	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(3,5-dimethoxy-phenoxy)-acetic acid::CHEMBL94488	Endothelin-1 receptor			 46.2							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146688&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11330927	104035277		CHEMBL94488				ZINC26670878	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269345	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CC(O)=O)c3ccccc23)c2ccccc2)n1	InChI=1S/C25H24N4O6/c1-15-12-16(2)28-24(27-15)35-22(23(33)34)25(17-8-4-3-5-9-17)18-10-6-7-11-19(18)29(14-21(31)32)20(30)13-26-25/h3-12,22,26H,13-14H2,1-2H3,(H,31,32)(H,33,34)/t22-,25+/m1/s1	JKNAAXSOIGHTLX-RDGATRHJSA-N	50146647	(S)-((S)-1-Carboxymethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL313867	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146647&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10140418	104035236		CHEMBL313867				ZINC13561042	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269346	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)cc1	InChI=1S/C31H30N4O5/c1-20-17-21(2)34-30(33-20)40-28(29(37)38)31(23-9-5-4-6-10-23)25-11-7-8-12-26(25)35(27(36)18-32-31)19-22-13-15-24(39-3)16-14-22/h4-17,28,32H,18-19H2,1-3H3,(H,37,38)/t28-,31+/m1/s1	VRSKDQFILRKSHK-MVSFAKPFSA-N	50146685	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL316878	Endothelin-1 receptor			 4.6							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146685&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10230546	104035274		CHEMBL316878				ZINC26666515	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269348	CCCCc1cccc(c1)[C@@]1(NCC(=O)N(Cc2c(F)cccc2Cl)c2ccccc12)[C@H](Oc1nc(C)cc(C)n1)C(O)=O	InChI=1S/C34H34ClFN4O4/c1-4-5-10-23-11-8-12-24(18-23)34(31(32(42)43)44-33-38-21(2)17-22(3)39-33)26-13-6-7-16-29(26)40(30(41)19-37-34)20-25-27(35)14-9-15-28(25)36/h6-9,11-18,31,37H,4-5,10,19-20H2,1-3H3,(H,42,43)/t31-,34+/m1/s1	AUSMSARLDRBCDW-FJQKOURKSA-N	50146731	(S)-[(S)-5-(3-Butyl-phenyl)-1-(2-chloro-6-fluoro-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL330135	Endothelin-1 receptor			 7.6							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146731&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11204331	104035320		CHEMBL330135					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269349	CCCCCCN1c2ccccc2[C@](NCC1=O)([C@H](Oc1nc(C)cc(C)n1)C(O)=O)c1ccccc1	InChI=1S/C29H34N4O4/c1-4-5-6-12-17-33-24-16-11-10-15-23(24)29(30-19-25(33)34,22-13-8-7-9-14-22)26(27(35)36)37-28-31-20(2)18-21(3)32-28/h7-11,13-16,18,26,30H,4-6,12,17,19H2,1-3H3,(H,35,36)/t26-,29+/m1/s1	YNFUBOJUAKNKLF-UHSQPCAPSA-N	50146715	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-hexyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL94810	Endothelin-1 receptor			 23.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146715&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11409474	104035304		CHEMBL94810				ZINC13561034	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269353	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cc(F)cc(F)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26F2N4O4/c1-18-12-19(2)35-29(34-18)40-27(28(38)39)30(21-8-4-3-5-9-21)24-10-6-7-11-25(24)36(26(37)16-33-30)17-20-13-22(31)15-23(32)14-20/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	HZWIXRSMTHDZGL-OFSOJUDTSA-N	50146664	(S)-[(S)-1-(3,5-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL95017	Endothelin-1 receptor			 7.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146664&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11398658	104035253		CHEMBL95017				ZINC26674460	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269354	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)cc(F)cc3F)c3ccccc23)c2cccc(c2)-c2ccccc2)n1	InChI=1S/C36H29F3N4O4/c1-21-15-22(2)42-35(41-21)47-33(34(45)46)36(25-12-8-11-24(16-25)23-9-4-3-5-10-23)28-13-6-7-14-31(28)43(32(44)19-40-36)20-27-29(38)17-26(37)18-30(27)39/h3-18,33,40H,19-20H2,1-2H3,(H,45,46)/t33-,36+/m1/s1	VEMZPXZQLOLLKQ-ILFWFZRHSA-N	50146679	(S)-[(S)-5-Biphenyl-3-yl-2-oxo-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL319754	Endothelin-1 receptor			 7.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146679&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11377200	104035268		CHEMBL319754				ZINC26670561	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269360	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)C2CCCCC2)cc1	InChI=1S/C31H36N4O5/c1-20-17-21(2)34-30(33-20)40-28(29(37)38)31(23-9-5-4-6-10-23)25-11-7-8-12-26(25)35(27(36)18-32-31)19-22-13-15-24(39-3)16-14-22/h7-8,11-17,23,28,32H,4-6,9-10,18-19H2,1-3H3,(H,37,38)/t28-,31+/m1/s1	PYYAHQASPOJSMT-MVSFAKPFSA-N	50146735	(S)-[(S)-5-Cyclohexyl-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL328073	Endothelin-1 receptor			 112							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146735&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11387205	104035324		CHEMBL328073				ZINC26670987	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269361	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cccc(Cl)c2)cc1	InChI=1S/C31H29ClN4O5/c1-19-15-20(2)35-30(34-19)41-28(29(38)39)31(22-7-6-8-23(32)16-22)25-9-4-5-10-26(25)36(27(37)17-33-31)18-21-11-13-24(40-3)14-12-21/h4-16,28,33H,17-18H2,1-3H3,(H,38,39)/t28-,31+/m1/s1	FRQPGCPVRMZTNE-MVSFAKPFSA-N	50146674	(S)-[(S)-5-(3-Chloro-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL96313	Endothelin-1 receptor			 25							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146674&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11238500	104035263		CHEMBL96313				ZINC26670028	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269365	Cc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccccc2)cc1	InChI=1S/C31H30N4O4/c1-20-13-15-23(16-14-20)19-35-26-12-8-7-11-25(26)31(32-18-27(35)36,24-9-5-4-6-10-24)28(29(37)38)39-30-33-21(2)17-22(3)34-30/h4-17,28,32H,18-19H2,1-3H3,(H,37,38)/t28-,31+/m1/s1	KRSWVPASAJDUGK-MVSFAKPFSA-N	50146712	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methyl-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL431087	Endothelin-1 receptor			 30.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146712&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11156692	104035301		CHEMBL431087				ZINC13561049	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269367	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CCO)c3ccccc23)c2ccccc2)n1	InChI=1S/C25H26N4O5/c1-16-14-17(2)28-24(27-16)34-22(23(32)33)25(18-8-4-3-5-9-18)19-10-6-7-11-20(19)29(12-13-30)21(31)15-26-25/h3-11,14,22,26,30H,12-13,15H2,1-2H3,(H,32,33)/t22-,25+/m1/s1	TUTZGEFUGWQBKP-RDGATRHJSA-N	50146729	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-hydroxy-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL328878	Endothelin-1 receptor			 6.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146729&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10298354	104035318		CHEMBL328878				ZINC13561041	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269368	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cc(F)c(F)c(F)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H25F3N4O4/c1-17-12-18(2)36-29(35-17)41-27(28(39)40)30(20-8-4-3-5-9-20)21-10-6-7-11-24(21)37(25(38)15-34-30)16-19-13-22(31)26(33)23(32)14-19/h3-14,27,34H,15-16H2,1-2H3,(H,39,40)/t27-,30+/m1/s1	JNUYVBGNCBJGHQ-OFSOJUDTSA-N	50146741	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3,4,5-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL94766	Endothelin-1 receptor			 11.8							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146741&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11342005	104035330		CHEMBL94766				ZINC26674424	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269370	Cc1cccc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)c1	InChI=1S/C31H26Cl2N2O4/c1-20-9-7-12-22(17-20)39-29(30(37)38)31(21-10-3-2-4-11-21)24-13-5-6-16-27(24)35(28(36)18-34-31)19-23-25(32)14-8-15-26(23)33/h2-17,29,34H,18-19H2,1H3,(H,37,38)/t29-,31+/m1/s1	NVONIBWWXNXALH-VEEOACQBSA-N	50146742	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-m-tolyloxy-acetic acid::CHEMBL94769	Endothelin-1 receptor			 29							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146742&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11410410	104035331		CHEMBL94769					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269377	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(Cl)cc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27ClN4O4/c1-19-16-20(2)34-29(33-19)39-27(28(37)38)30(22-8-4-3-5-9-22)24-10-6-7-11-25(24)35(26(36)17-32-30)18-21-12-14-23(31)15-13-21/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	TWGYPFLCDZVWJV-OFSOJUDTSA-N	50146736	(S)-[(S)-1-(4-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL313870	Endothelin-1 receptor			 17.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146736&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11753090	104035325		CHEMBL313870				ZINC26673851	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269378	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(cc3)C(F)(F)F)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H27F3N4O4/c1-19-16-20(2)37-29(36-19)42-27(28(40)41)30(22-8-4-3-5-9-22)24-10-6-7-11-25(24)38(26(39)17-35-30)18-21-12-14-23(15-13-21)31(32,33)34/h3-16,27,35H,17-18H2,1-2H3,(H,40,41)/t27-,30+/m1/s1	XAJNNLNUOAQGQO-OFSOJUDTSA-N	50146740	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(4-trifluoromethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL91926	Endothelin-1 receptor			 17							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146740&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10166981	104035329		CHEMBL91926				ZINC26665876	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269382	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CC3CC3)c3ccccc23)c2ccccc2)n1	InChI=1S/C27H28N4O4/c1-17-14-18(2)30-26(29-17)35-24(25(33)34)27(20-8-4-3-5-9-20)21-10-6-7-11-22(21)31(16-19-12-13-19)23(32)15-28-27/h3-11,14,19,24,28H,12-13,15-16H2,1-2H3,(H,33,34)/t24-,27+/m1/s1	QWIJRDPSRHJFIY-SQHAQQRYSA-N	50146686	(S)-((S)-1-Cyclopropylmethyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL96318	Endothelin-1 receptor			 7.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146686&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11155687	104035275		CHEMBL96318				ZINC13561036	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269383	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)ccc(F)c3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H25F3N4O4/c1-17-14-18(2)36-29(35-17)41-27(28(39)40)30(19-8-4-3-5-9-19)21-10-6-7-11-24(21)37(25(38)15-34-30)16-20-22(31)12-13-23(32)26(20)33/h3-14,27,34H,15-16H2,1-2H3,(H,39,40)/t27-,30+/m1/s1	NKONTEUZTOHVNH-OFSOJUDTSA-N	50146743	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,3,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL94580	Endothelin-1 receptor			 2.4							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146743&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10120430	104035332		CHEMBL94580				ZINC55865581	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269385	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cc(F)ccc3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26F2N4O4/c1-18-14-19(2)35-29(34-18)40-27(28(38)39)30(21-8-4-3-5-9-21)23-10-6-7-11-25(23)36(26(37)16-33-30)17-20-15-22(31)12-13-24(20)32/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	ADOZPFPWNPYHGT-OFSOJUDTSA-N	50146703	(S)-[(S)-1-(2,5-Difluoro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL94438	Endothelin-1 receptor			 6.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146703&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11191999	104035292		CHEMBL94438				ZINC26670990	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269388	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3ccc(cc3)C(O)=O)c3ccccc23)c2ccccc2)n1	InChI=1S/C31H28N4O6/c1-19-16-20(2)34-30(33-19)41-27(29(39)40)31(23-8-4-3-5-9-23)24-10-6-7-11-25(24)35(26(36)17-32-31)18-21-12-14-22(15-13-21)28(37)38/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)(H,39,40)/t27-,31+/m1/s1	RITJHYCZRLLXJJ-JOMNFKBKSA-N	50146745	4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-ylmethyl}-benzoic acid::CHEMBL96463	Endothelin-1 receptor			 123							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146745&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11432855	104035334		CHEMBL96463				ZINC26666392	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269390	OC(=O)[C@@H](Oc1cccc(Cl)c1)[C@]1(NCC(=O)N(Cc2c(Cl)cccc2Cl)c2ccccc12)c1ccccc1	InChI=1S/C30H23Cl3N2O4/c31-20-10-6-11-21(16-20)39-28(29(37)38)30(19-8-2-1-3-9-19)23-12-4-5-15-26(23)35(27(36)17-34-30)18-22-24(32)13-7-14-25(22)33/h1-16,28,34H,17-18H2,(H,37,38)/t28-,30+/m1/s1	CSEUMOSCUZUMNY-DGPALRBDSA-N	50146732	(S)-(3-Chloro-phenoxy)-[(S)-1-(2,6-dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96325	Endothelin-1 receptor			 101							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146732&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11455999	104035321		CHEMBL96325					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269392	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H26Cl2N4O4/c1-18-15-19(2)35-29(34-18)40-27(28(38)39)30(20-9-4-3-5-10-20)22-11-6-7-14-25(22)36(26(37)16-33-30)17-21-23(31)12-8-13-24(21)32/h3-15,27,33H,16-17H2,1-2H3,(H,38,39)/t27-,30+/m1/s1	NMXUCISAFBDZIZ-OFSOJUDTSA-N	50146737	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL330104	Endothelin-1 receptor			 1.8							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146737&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9894443	104035326		CHEMBL330104				ZINC53021968	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269394	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cccc(c2)C(F)(F)F)cc1	InChI=1S/C32H29F3N4O5/c1-19-15-20(2)38-30(37-19)44-28(29(41)42)31(22-7-6-8-23(16-22)32(33,34)35)25-9-4-5-10-26(25)39(27(40)17-36-31)18-21-11-13-24(43-3)14-12-21/h4-16,28,36H,17-18H2,1-3H3,(H,41,42)/t28-,31+/m1/s1	FQXLGGFHDJJJJO-MVSFAKPFSA-N	50146738	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-(3-trifluoromethyl-phenyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL316851	Endothelin-1 receptor			 24.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146738&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11467573	104035327		CHEMBL316851				ZINC26672964	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269396	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cccc(C)c2)cc1	InChI=1S/C32H32N4O5/c1-20-8-7-9-24(16-20)32(29(30(38)39)41-31-34-21(2)17-22(3)35-31)26-10-5-6-11-27(26)36(28(37)18-33-32)19-23-12-14-25(40-4)15-13-23/h5-17,29,33H,18-19H2,1-4H3,(H,38,39)/t29-,32+/m1/s1	DWRQMVBEIBBSTC-PPTMTGTBSA-N	50146708	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL317510	Endothelin-1 receptor			 6.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146708&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11284285	104035297		CHEMBL317510				ZINC26670023	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269397	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CCN3CCOCC3)c3ccccc23)c2ccccc2)n1	InChI=1S/C29H33N5O5/c1-20-18-21(2)32-28(31-20)39-26(27(36)37)29(22-8-4-3-5-9-22)23-10-6-7-11-24(23)34(25(35)19-30-29)13-12-33-14-16-38-17-15-33/h3-11,18,26,30H,12-17,19H2,1-2H3,(H,36,37)/t26-,29+/m1/s1	RUXNEULYFPIVIB-UHSQPCAPSA-N	50146744	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(2-morpholin-4-yl-ethyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96193	Endothelin-1 receptor			 126							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146744&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11318559	104035333		CHEMBL96193				ZINC13561039	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269401	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)c(F)c(F)c(F)c3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H23F5N4O4/c1-15-12-16(2)38-29(37-15)43-27(28(41)42)30(17-8-4-3-5-9-17)19-10-6-7-11-20(19)39(21(40)13-36-30)14-18-22(31)24(33)26(35)25(34)23(18)32/h3-12,27,36H,13-14H2,1-2H3,(H,41,42)/t27-,30+/m1/s1	DVNMKMKQUAYZDJ-OFSOJUDTSA-N	50146739	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-2-oxo-1-pentafluorophenylmethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL406551	Endothelin-1 receptor			 6.8							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146739&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11478911	104035328		CHEMBL406551				ZINC26664920	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269403	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCCOc3ccccc23)c2ccccc2)n1	InChI=1S/C23H23N3O4/c1-15-14-16(2)26-22(25-15)30-20(21(27)28)23(17-8-4-3-5-9-17)18-10-6-7-11-19(18)29-13-12-24-23/h3-11,14,20,24H,12-13H2,1-2H3,(H,27,28)/t20-,23+/m1/s1	XCDNXPGYLFIOLD-OFNKIYASSA-N	50146746	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-5-phenyl-2,3,4,5-tetrahydro-benzo[f][1,4]oxazepin-5-yl)-acetic acid::CHEMBL96831	Endothelin-1 receptor			 69.8							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146746&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11235126	104035335		CHEMBL96831				ZINC13561030	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269406	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CCCc3ccccc3)c3ccccc23)c2ccccc2)n1	InChI=1S/C32H32N4O4/c1-22-20-23(2)35-31(34-22)40-29(30(38)39)32(25-15-7-4-8-16-25)26-17-9-10-18-27(26)36(28(37)21-33-32)19-11-14-24-12-5-3-6-13-24/h3-10,12-13,15-18,20,29,33H,11,14,19,21H2,1-2H3,(H,38,39)/t29-,32+/m1/s1	AXVBSGVXXMZTEC-PPTMTGTBSA-N	50146669	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(3-phenyl-propyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL96114	Endothelin-1 receptor			 17.1							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146669&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11410074	104035258		CHEMBL96114				ZINC26670864	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269412	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3cccc(Cl)c3)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H27ClN4O4/c1-19-15-20(2)34-29(33-19)39-27(28(37)38)30(22-10-4-3-5-11-22)24-13-6-7-14-25(24)35(26(36)17-32-30)18-21-9-8-12-23(31)16-21/h3-16,27,32H,17-18H2,1-2H3,(H,37,38)/t27-,30+/m1/s1	GGEVZGHUELFPFK-OFSOJUDTSA-N	50146728	(S)-[(S)-1-(3-Chloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL327976	Endothelin-1 receptor			 5.8							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146728&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10187261	104035317		CHEMBL327976				ZINC26670747	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269414	CSc1cnc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccccc23)c2ccccc2)nc1	InChI=1S/C23H22N4O4S/c1-27-18-11-7-6-10-17(18)23(26-14-19(27)28,15-8-4-3-5-9-15)20(21(29)30)31-22-24-12-16(32-2)13-25-22/h3-13,20,26H,14H2,1-2H3,(H,29,30)/t20-,23+/m1/s1	CTXGHPQMXKYMJZ-OFNKIYASSA-N	50146747	(S)-((S)-1-Methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-(5-methylsulfanyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL264625	Endothelin-1 receptor			 6600							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146747&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11465096	104035336		CHEMBL264625				ZINC13561027	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269416	Cc1nc(C(O)=O)c2CN[C@@]([C@H](Oc3nc(C)cc(C)n3)C(O)=O)(c3ccccc3)c3ccccc3-n12	InChI=1S/C27H25N5O5/c1-15-13-16(2)30-26(29-15)37-23(25(35)36)27(18-9-5-4-6-10-18)19-11-7-8-12-20(19)32-17(3)31-22(24(33)34)21(32)14-28-27/h4-13,23,28H,14H2,1-3H3,(H,33,34)(H,35,36)/t23-,27+/m1/s1	JGCMJLQTOLPTCY-KCWPFWIISA-N	50146721	(S)-6-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-1-methyl-6-phenyl-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid::CHEMBL330045	Endothelin-1 receptor			 604							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146721&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11202819	104035310		CHEMBL330045				ZINC13561031	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269417	CCCCc1cccc(c1)[C@@]1(NCC(=O)N(Cc2ccc(OC)cc2)c2ccccc12)[C@H](Oc1nc(C)cc(C)n1)C(O)=O	InChI=1S/C35H38N4O5/c1-5-6-10-25-11-9-12-27(20-25)35(32(33(41)42)44-34-37-23(2)19-24(3)38-34)29-13-7-8-14-30(29)39(31(40)21-36-35)22-26-15-17-28(43-4)18-16-26/h7-9,11-20,32,36H,5-6,10,21-22H2,1-4H3,(H,41,42)/t32-,35+/m1/s1	MAJFWFWHJWCHLH-LDNVYYCDSA-N	50146675	(S)-[(S)-5-(3-Butyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL422068	Endothelin-1 receptor			 7.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146675&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11444738	104035264		CHEMBL422068				ZINC26658714	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269418	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2ccc(F)c(C)c2)cc1	InChI=1S/C32H31FN4O5/c1-19-15-23(11-14-26(19)33)32(29(30(39)40)42-31-35-20(2)16-21(3)36-31)25-7-5-6-8-27(25)37(28(38)17-34-32)18-22-9-12-24(41-4)13-10-22/h5-16,29,34H,17-18H2,1-4H3,(H,39,40)/t29-,32+/m1/s1	FGGUYHAUIAJAKH-PPTMTGTBSA-N	50146676	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-5-(4-fluoro-3-methyl-phenyl)-1-(4-methoxy-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL94934	Endothelin-1 receptor			 7.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146676&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11330570	104035265		CHEMBL94934				ZINC26675252	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269419	COc1ccc(CN2c3ccccc3[C@](NCC2=O)([C@H](Oc2nc(C)cc(C)n2)C(O)=O)c2cccc(OC)c2)cc1	InChI=1S/C32H32N4O6/c1-20-16-21(2)35-31(34-20)42-29(30(38)39)32(23-8-7-9-25(17-23)41-4)26-10-5-6-11-27(26)36(28(37)18-33-32)19-22-12-14-24(40-3)15-13-22/h5-17,29,33H,18-19H2,1-4H3,(H,38,39)/t29-,32+/m1/s1	UMVOCHGUCRDMRD-PPTMTGTBSA-N	50146714	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-5-(3-methoxy-phenyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL316629	Endothelin-1 receptor			 10.2							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146714&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11342089	104035303		CHEMBL316629				ZINC26672961	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269421	COc1cnc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(C)c3ccccc23)c2ccccc2)nc1	InChI=1S/C23H22N4O5/c1-27-18-11-7-6-10-17(18)23(26-14-19(27)28,15-8-4-3-5-9-15)20(21(29)30)32-22-24-12-16(31-2)13-25-22/h3-13,20,26H,14H2,1-2H3,(H,29,30)/t20-,23+/m1/s1	WHEOLVDPGZPPSM-OFNKIYASSA-N	50146690	(S)-(5-Methoxy-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL318683	Endothelin-1 receptor			 384							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146690&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11362537	104035279		CHEMBL318683				ZINC13561026	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269422	CCCCc1cccc(c1)[C@@]1(NCC(=O)N(Cc2c(C)cc(C)cc2C)c2ccccc12)[C@H](Oc1nc(C)cc(C)n1)C(O)=O	InChI=1S/C37H42N4O4/c1-7-8-12-28-13-11-14-29(20-28)37(34(35(43)44)45-36-39-26(5)19-27(6)40-36)31-15-9-10-16-32(31)41(33(42)21-38-37)22-30-24(3)17-23(2)18-25(30)4/h9-11,13-20,34,38H,7-8,12,21-22H2,1-6H3,(H,43,44)/t34-,37+/m1/s1	WFGXYWSSRLHSJI-BLPFIKBVSA-N	50146657	(S)-[(S)-5-(3-Butyl-phenyl)-2-oxo-1-(2,4,6-trimethyl-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid::CHEMBL96303	Endothelin-1 receptor			 18.3							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146657&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11330923	104035246		CHEMBL96303				ZINC26667887	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269423	CCCCC[C@@]1(NCC(=O)N(Cc2ccc(OC)cc2)c2ccccc12)[C@H](Oc1nc(C)cc(C)n1)C(O)=O	InChI=1S/C30H36N4O5/c1-5-6-9-16-30(27(28(36)37)39-29-32-20(2)17-21(3)33-29)24-10-7-8-11-25(24)34(26(35)18-31-30)19-22-12-14-23(38-4)15-13-22/h7-8,10-15,17,27,31H,5-6,9,16,18-19H2,1-4H3,(H,36,37)/t27-,30+/m1/s1	AAKCZJIYTMOXJF-OFSOJUDTSA-N	50146665	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-1-(4-methoxy-benzyl)-2-oxo-5-pentyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL329744	Endothelin-1 receptor			 355							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146665&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11307120	104035254		CHEMBL329744				ZINC13561050	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269426	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCCCc3ccccc23)c2ccccc2)n1	InChI=1S/C24H25N3O3/c1-16-15-17(2)27-23(26-16)30-21(22(28)29)24(19-11-4-3-5-12-19)20-13-7-6-9-18(20)10-8-14-25-24/h3-7,9,11-13,15,21,25H,8,10,14H2,1-2H3,(H,28,29)/t21-,24+/m1/s1	FFTXFLYVZRLOGQ-QPPBQGQZSA-N	50146720	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-yl)-acetic acid::CHEMBL96331	Endothelin-1 receptor			 91.7							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146720&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11441050	104035309		CHEMBL96331				ZINC13561029	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269429	Cc1ccccc1O[C@H](C(O)=O)[C@]1(NCC(=O)N(Cc2c(Cl)cccc2Cl)c2ccccc12)c1ccccc1	InChI=1S/C31H26Cl2N2O4/c1-20-10-5-8-17-27(20)39-29(30(37)38)31(21-11-3-2-4-12-21)23-13-6-7-16-26(23)35(28(36)18-34-31)19-22-24(32)14-9-15-25(22)33/h2-17,29,34H,18-19H2,1H3,(H,37,38)/t29-,31+/m1/s1	WBESQFWQKSSZML-VEEOACQBSA-N	50146677	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-o-tolyloxy-acetic acid::CHEMBL317981	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146677&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11284400	104035266		CHEMBL317981				ZINC26670721	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269434	Cc1ccc(C)c(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(Cl)cccc3Cl)c3ccccc23)c2ccccc2)c1	InChI=1S/C32H28Cl2N2O4/c1-20-15-16-21(2)28(17-20)40-30(31(38)39)32(22-9-4-3-5-10-22)24-11-6-7-14-27(24)36(29(37)18-35-32)19-23-25(33)12-8-13-26(23)34/h3-17,30,35H,18-19H2,1-2H3,(H,38,39)/t30-,32+/m1/s1	MTTFWJGDJLLRIK-BHYZAODMSA-N	50146650	(S)-[(S)-1-(2,6-Dichloro-benzyl)-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-(2,5-dimethyl-phenoxy)-acetic acid::CHEMBL421184	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146650&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11192438	104035239		CHEMBL421184				ZINC26674983	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269435	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(Cc3c(F)cc(F)cc3F)c3ccccc23)c2ccccc2)n1	InChI=1S/C30H25F3N4O4/c1-17-12-18(2)36-29(35-17)41-27(28(39)40)30(19-8-4-3-5-9-19)22-10-6-7-11-25(22)37(26(38)15-34-30)16-21-23(32)13-20(31)14-24(21)33/h3-14,27,34H,15-16H2,1-2H3,(H,39,40)/t27-,30+/m1/s1	GDAGOGOXJLUVGB-OFSOJUDTSA-N	50146683	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-[(S)-2-oxo-5-phenyl-1-(2,4,6-trifluoro-benzyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl]-acetic acid::CHEMBL329477	Endothelin-1 receptor			 2.5							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146683&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10166543	104035272		CHEMBL329477					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50269436	Cc1cc(C)nc(O[C@H](C(O)=O)[C@]2(NCC(=O)N(CCCC(O)=O)c3ccccc23)c2ccccc2)n1	InChI=1S/C27H28N4O6/c1-17-15-18(2)30-26(29-17)37-24(25(35)36)27(19-9-4-3-5-10-19)20-11-6-7-12-21(20)31(22(32)16-28-27)14-8-13-23(33)34/h3-7,9-12,15,24,28H,8,13-14,16H2,1-2H3,(H,33,34)(H,35,36)/t24-,27+/m1/s1	BYBPPGGQNVVISN-SQHAQQRYSA-N	50146701	4-{(S)-5-[(S)-Carboxy-(4,6-dimethyl-pyrimidin-2-yloxy)-methyl]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[e][1,4]diazepin-1-yl}-butyric acid::CHEMBL330359	Endothelin-1 receptor			 45.9							ChEMBL	10.1021/jm031115r	10.7270/Q2Z89BVT	15139756			Bolli, MH; Marfurt, J; Grisostomi, C; Boss, C; Binkert, C; Hess, P; Treiber, A; Thorin, E; Morrison, K; Buchmann, S; Bur, D; Ramuz, H; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146701&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11156376	104035290		CHEMBL330359				ZINC13561044	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363216	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)-c1ncco1)C(=O)CCc1ccc(OCCOCCOCCOCCOCCC(=O)Nc2ccc(CCC(=O)CC(C)=O)cc2)cc1	InChI=1S/C52H59N5O13S/c1-38(58)35-44(59)16-9-39-7-14-43(15-8-39)55-49(60)22-25-64-27-28-65-29-30-66-31-32-67-33-34-68-45-17-10-40(11-18-45)12-20-51(61)57(2)37-42-36-41(52-53-24-26-69-52)13-19-46(42)47-5-3-4-6-48(47)71(62,63)56-50-21-23-54-70-50/h3-8,10-11,13-15,17-19,21,23-24,26,36,56H,9,12,16,20,22,25,27-35,37H2,1-2H3,(H,55,60)	YGFGPUBPCDIYGI-UHFFFAOYSA-N	50196999	CHEMBL413001::N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2-[2-(2-{2-[4-(2-{[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-methyl-carbamoyl}-ethyl)-phenoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionamide	Endothelin-1 receptor			 21.6							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196999&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439114	104078527		CHEMBL413001					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363217	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)-c1ncco1)C(=O)CCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)Nc1ccc(CCC(=O)CC(C)=O)cc1	InChI=1S/C62H86N6O20S/c1-49(69)46-54(70)16-12-50-10-14-53(15-11-50)66-59(72)19-23-76-26-28-78-30-32-80-34-36-82-38-40-84-42-44-86-45-43-85-41-39-83-37-35-81-33-31-79-29-27-77-24-21-63-58(71)8-5-9-61(73)68(2)48-52-47-51(62-64-22-25-87-62)13-17-55(52)56-6-3-4-7-57(56)89(74,75)67-60-18-20-65-88-60/h3-4,6-7,10-11,13-15,17-18,20,22,25,47,67H,5,8-9,12,16,19,21,23-24,26-46,48H2,1-2H3,(H,63,71)(H,66,72)	SVDLMZYXLYEZOL-UHFFFAOYSA-N	50197000	CHEMBL429019::N-(35-{[4-(3,5-dioxohexyl)phenyl]carbamoyl}-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-yl)-N'-methyl-N'-{[5-(1,3-oxazol-2-yl)-2-{2-[(1,2-oxazol-5-yl)sulfamoyl]phenyl}phenyl]methyl}pentanediamide	Endothelin-1 receptor			 7.7							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197000&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439108	104078528		CHEMBL429019					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363218	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)-c1ncco1)C(=O)CC(C)(C)C	InChI=1S/C26H28N4O5S/c1-26(2,3)16-24(31)30(4)17-19-15-18(25-27-13-14-34-25)9-10-20(19)21-7-5-6-8-22(21)36(32,33)29-23-11-12-28-35-23/h5-15,29H,16-17H2,1-4H3	IDLNVQZPQPDNDW-UHFFFAOYSA-N	50197001	CHEMBL238539::N-[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-3,3,N-trimethyl-butyramide	Endothelin-1 receptor			 1							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197001&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439102	104078529		CHEMBL238539				ZINC28886864	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363220	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)-c1ncco1)C(=O)Cc1ccc(OCCOCCOCCOCCOCCC(=O)Nc2ccc(CCC(=O)CC(C)=O)cc2)cc1	InChI=1S/C51H57N5O13S/c1-37(57)33-43(58)15-9-38-7-13-42(14-8-38)54-48(59)20-23-63-25-26-64-27-28-65-29-30-66-31-32-67-44-16-10-39(11-17-44)34-50(60)56(2)36-41-35-40(51-52-22-24-68-51)12-18-45(41)46-5-3-4-6-47(46)70(61,62)55-49-19-21-53-69-49/h3-8,10-14,16-19,21-22,24,35,55H,9,15,20,23,25-34,36H2,1-2H3,(H,54,59)	OEJAHNMAKBDSJW-UHFFFAOYSA-N	50197002	CHEMBL268201::N-[4-(3,5-dioxo-hexyl)-phenyl]-3-{2-[2-(2-{2-[4-({[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-methyl-carbamoyl}-methyl)-phenoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-propionamide	Endothelin-1 receptor			 4.6							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197002&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439111	104078530		CHEMBL268201					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363227	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)-c1ncco1)C(=O)CCOCCOCCOCCOCCOCCOCCOCCC(=O)Nc1ccc(CCC(=O)CC(C)=O)cc1	InChI=1S/C50H63N5O15S/c1-38(56)35-43(57)13-9-39-7-11-42(12-8-39)53-47(58)16-20-62-23-25-64-27-29-66-31-33-68-34-32-67-30-28-65-26-24-63-21-17-49(59)55(2)37-41-36-40(50-51-19-22-69-50)10-14-44(41)45-5-3-4-6-46(45)71(60,61)54-48-15-18-52-70-48/h3-8,10-12,14-15,18-19,22,36,54H,9,13,16-17,20-21,23-35,37H2,1-2H3,(H,53,58)	UBBBOFHNARFNBK-UHFFFAOYSA-N	50197004	3-{2-[2-(2-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenylcarbamoyl]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-N-[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-propionamide::CHEMBL398070	Endothelin-1 receptor			 8							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197004&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439106	104078532		CHEMBL398070					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363228	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)-c1ncco1)C(=O)COCCOCCOCCOCCC(=O)Nc1ccc(CCC(=O)CC(C)=O)cc1	InChI=1S/C43H49N5O12S/c1-31(49)27-36(50)13-9-32-7-11-35(12-8-32)46-40(51)16-19-55-21-22-56-23-24-57-25-26-58-30-42(52)48(2)29-34-28-33(43-44-18-20-59-43)10-14-37(34)38-5-3-4-6-39(38)61(53,54)47-41-15-17-45-60-41/h3-8,10-12,14-15,17-18,20,28,47H,9,13,16,19,21-27,29-30H2,1-2H3,(H,46,51)	VWSKYKKEFJUDNW-UHFFFAOYSA-N	50197003	CHEMBL241460::N-[4-(3,5-dioxo-hexyl)-phenyl]-3-(2-{2-[2-({[2'-(isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-methyl-carbamoyl}-methoxy)-ethoxy]-ethoxy}-ethoxy)-propionamide	Endothelin-1 receptor			 1.6							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197003&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439103	104078531		CHEMBL241460					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50363229	CN(Cc1cc(OCCOCCOCCOCCC(=O)Nc2ccc(CCC(=O)CC(C)=O)cc2)ccc1-c1ccccc1S(=O)(=O)Nc1ccno1)C(=O)CC(C)(C)C	InChI=1S/C44H56N4O11S/c1-32(49)28-36(50)15-12-33-10-13-35(14-11-33)46-41(51)19-21-55-22-23-56-24-25-57-26-27-58-37-16-17-38(34(29-37)31-48(5)43(52)30-44(2,3)4)39-8-6-7-9-40(39)60(53,54)47-42-18-20-45-59-42/h6-11,13-14,16-18,20,29,47H,12,15,19,21-28,30-31H2,1-5H3,(H,46,51)	MGOQYQRCURWWNQ-UHFFFAOYSA-N	50197005	CHEMBL436821::N-[4-{2-[2-(2-{2-[4-(3,5-dioxo-hexyl)-phenylcarbamoyl]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-2'-(isoxazol-5-ylsulfamoyl)-biphenyl-2-ylmethyl]-3,3,N-trimethyl-butyramide	Endothelin-1 receptor			 44.9							ChEMBL	10.1016/j.bmcl.2006.10.009	10.7270/Q2DZ07ZF	17055724			Doppalapudi, VR; Tryder, N; Li, L; Aja, T; Griffith, D; Liao, FF; Roxas, G; Ramprasad, MP; Bradshaw, C; Barbas, CF	CovX Research LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197005&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44439105	104078533		CHEMBL436821				ZINC95541560	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50433407	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)cc(cc1OCCO)-c1ncccn1	InChI=1S/C26H22F3N3O6S/c1-36-21-5-2-3-6-22(21)38-24-20(32-39(34,35)19-9-7-18(8-10-19)26(27,28)29)15-17(16-23(24)37-14-13-33)25-30-11-4-12-31-25/h2-12,15-16,32-33H,13-14H2,1H3	WMTQUGCQXPZLRJ-UHFFFAOYSA-N	50130311	CHEMBL3633039	Endothelin-1 receptor			 130							ChEMBL	10.1021/acs.jmedchem.5b00258	10.7270/Q22J6DPZ	26200936			Gillis, EP; Eastman, KJ; Hill, MD; Donnelly, DJ; Meanwell, NA	Bristol-Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130311&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122194934	321903044		CHEMBL3633039					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50433408	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)S(F)(F)(F)(F)F)cc(cc1OCCO)-c1ncccn1	InChI=1S/C25H22F5N3O6S2/c1-37-21-5-2-3-6-22(21)39-24-20(15-17(16-23(24)38-14-13-34)25-31-11-4-12-32-25)33-40(35,36)18-7-9-19(10-8-18)41(26,27,28,29)30/h2-12,15-16,33-34H,13-14H2,1H3	OUWVSODMIMINEM-UHFFFAOYSA-N	50130314	CHEMBL3633040	Endothelin-1 receptor			 112							ChEMBL	10.1021/acs.jmedchem.5b00258	10.7270/Q22J6DPZ	26200936			Gillis, EP; Eastman, KJ; Hill, MD; Donnelly, DJ; Meanwell, NA	Bristol-Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130314&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122194935	321903045		CHEMBL3633040					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466040	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H57N7O12/c1-6-23(3)36(41(59)48-33(43(61)62)20-27-22-44-29-16-12-11-15-28(27)29)50-42(60)37(24(4)7-2)49-40(58)32(21-35(54)55)47-38(56)30(17-18-34(52)53)46-39(57)31(45-25(5)51)19-26-13-9-8-10-14-26/h8-16,22-24,30-33,36-37,44H,6-7,17-21H2,1-5H3,(H,45,51)(H,46,57)(H,47,56)(H,48,59)(H,49,58)(H,50,60)(H,52,53)(H,54,55)(H,61,62)/t23-,24-,30-,31+,32-,33-,36-,37-/m0/s1	CAOZFSYRDJCUQV-CCEHOFDQSA-N	50281564	(S)-4-((R)-2-Acetylamino-3-phenyl-propionylamino)-4-((S)-2-carboxy-1-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butylcarbamoyl}-ethylcarbamoyl)-butyric acid::CHEMBL147908	Endothelin-1 receptor			 650							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281564&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44364522	104123238		CHEMBL147908					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466041	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O8/c1-8-30(5)42(47(61)54-41(49(63)64)27-35-28-50-37-23-17-16-22-36(35)37)56-48(62)43(31(6)9-2)55-46(60)40(26-34-20-14-11-15-21-34)53-44(58)38(24-29(3)4)52-45(59)39(51-32(7)57)25-33-18-12-10-13-19-33/h10-23,28-31,38-43,50H,8-9,24-27H2,1-7H3,(H,51,57)(H,52,59)(H,53,58)(H,54,61)(H,55,60)(H,56,62)(H,63,64)/t30-,31-,38-,39+,40-,41-,42-,43-/m0/s1	BQFWUVDRXODPBL-HZNXMSJUSA-N	50045240	(S)-2-[(S)-2-((2S,5S)-2-{(S)-2-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(S)-1H-indol-3-yl-propionic acid::Ac-D-Phe-Leu-Phe-Ile-Ile-Trp::CHEMBL327350	Endothelin-1 receptor			 1180							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045240&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321081	103976331		CHEMBL327350					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466042	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35+,36-,37-,38-,40-,41-/m0/s1	GNRBLKLDFZWDTC-ALDIRDDTSA-N	50045244	(S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-D-Phe-Asp-Ile-Ile-Trp::CHEMBL313984	Endothelin-1 receptor			 200							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045244&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321226	103976335		CHEMBL313984					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466043	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C38H50N6O9/c1-6-22(4)33(37(51)43-31(38(52)53)18-25-20-39-27-15-11-10-14-26(25)27)44-36(50)30(19-32(46)47)42-34(48)28(16-21(2)3)41-35(49)29(40-23(5)45)17-24-12-8-7-9-13-24/h7-15,20-22,28-31,33,39H,6,16-19H2,1-5H3,(H,40,45)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H,46,47)(H,52,53)/t22-,28-,29+,30-,31-,33-/m0/s1	RKEZXGDDBOFKKM-HRHWTSPYSA-N	50045235	(S)-3-[(R)-2-((1S,5S)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Leu-Asp-Ile-Trp::CHEMBL87724	Endothelin-1 receptor			>10000							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321075	103976326		CHEMBL87724				ZINC26575973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466046	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30+,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-DZZYDSNESA-N	50000566	(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-((S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL289687	Endothelin-1 receptor			 9500							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000566&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284284	103915114		CHEMBL289687				ZINC95607973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466048	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C34H45N5O6/c1-6-20(3)29(32(42)37-28(34(44)45)18-24-19-35-26-16-12-11-15-25(24)26)39-33(43)30(21(4)7-2)38-31(41)27(36-22(5)40)17-23-13-9-8-10-14-23/h8-16,19-21,27-30,35H,6-7,17-18H2,1-5H3,(H,36,40)(H,37,42)(H,38,41)(H,39,43)(H,44,45)/t20-,21-,27+,28-,29-,30-/m0/s1	KSMIQAULFAKWPP-VIPNTURPSA-N	50045247	3-((R)-2-Acetylamino-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-((S)-(S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Ile-Ile-Trp::CHEMBL312916	Endothelin-1 receptor			>10000							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045247&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321073	103976338		CHEMBL312916				ZINC26576451	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466050	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35+,36+,37-,38-,40-,41-/m0/s1	GNRBLKLDFZWDTC-HVVAYYAISA-N	50281565	(S)-3-[(R)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::CHEMBL146155	Endothelin-1 receptor			 930							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281565&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44364480	104123239		CHEMBL146155					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466052	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30-,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-CXDMSSIXSA-N	50000553	(S)-3-{(S)-2-[(S)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::Ac-His-Leu-Asp-Ile-Ile-D-Trp::CHEMBL432091	Endothelin-1 receptor			>50000							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000553&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284385	103915101		CHEMBL432091				ZINC95614744	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466055	CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C28H34N4O5/c1-4-17(2)25(32-26(34)23(30-18(3)33)14-19-10-6-5-7-11-19)27(35)31-24(28(36)37)15-20-16-29-22-13-9-8-12-21(20)22/h5-13,16-17,23-25,29H,4,14-15H2,1-3H3,(H,30,33)(H,31,35)(H,32,34)(H,36,37)/t17-,23+,24-,25-/m0/s1	GOQQMBMRNCMDQC-VUHWMDJISA-N	50045258	(S)-2-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::Ac-D-Phe-Ile-Trp::CHEMBL330489	Endothelin-1 receptor			 8000							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321032	103976349		CHEMBL330489				ZINC26578160	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466056	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C38H50N6O9/c1-6-21(3)32(36(50)42-30(38(52)53)18-25-20-39-27-16-12-11-15-26(25)27)44-37(51)33(22(4)7-2)43-35(49)29(19-31(46)47)41-34(48)28(40-23(5)45)17-24-13-9-8-10-14-24/h8-16,20-22,28-30,32-33,39H,6-7,17-19H2,1-5H3,(H,40,45)(H,41,48)(H,42,50)(H,43,49)(H,44,51)(H,46,47)(H,52,53)/t21-,22-,28+,29-,30-,32-,33-/m0/s1	XYVDWQKXXNSVGP-MGIIKFKASA-N	50045251	3-((R)-2-Acetylamino-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-((S)-(S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Asp-Ile-Ile-Trp::CHEMBL315658	Endothelin-1 receptor			 9100							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045251&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321033	103976342		CHEMBL315658				ZINC26578236	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466057	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33-,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-KTCACYFJSA-N	50045248	(S)-3-[(S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-Phe-Leu-Asp-Ile-Ile-Trp::CHEMBL273391	Endothelin-1 receptor			 18400							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045248&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321103	103976339		CHEMBL273391				ZINC95541374	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466090	CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C45H61N9O10/c1-6-24(3)38(43(61)52-36(45(63)64)20-28-23-48-32-16-11-9-14-30(28)32)54-44(62)39(25(4)7-2)53-42(60)35(21-37(56)57)51-40(58)33(17-12-18-46)50-41(59)34(49-26(5)55)19-27-22-47-31-15-10-8-13-29(27)31/h8-11,13-16,22-25,33-36,38-39,47-48H,6-7,12,17-21,46H2,1-5H3,(H,49,55)(H,50,59)(H,51,58)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t24-,25-,33+,34-,35+,36+,38+,39+/m1/s1	ZMZJOZFSFHZWRN-FEBBOSPPSA-N	50281576	(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(1H-indol-3-yl)-propionylamino]-5-amino-pentanoylamino}-N-((1S,2R)-1-{(1S,2R)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL150719	Endothelin-1 receptor			 130							ChEMBL	10.1016/S0960-894X(01)81219-1	10.7270/Q27081C5				Spellmeyer, DC; Brown, S; Stauber, GB; Geysen, H; Valerio, R	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281576&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44366033	104123250		CHEMBL150719					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466093	CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)CN(Cc1ccccc1)C(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-28(3)41(44(60)51-38(47(63)64)23-33-25-48-35-21-15-14-20-34(33)35)53-45(61)42(29(4)7-2)52-43(59)36(24-40(57)58)50-39(56)27-54(26-32-18-12-9-13-19-32)46(62)37(49-30(5)55)22-31-16-10-8-11-17-31/h8-21,25,28-29,36-38,41-42,48H,6-7,22-24,26-27H2,1-5H3,(H,49,55)(H,50,56)(H,51,60)(H,52,59)(H,53,61)(H,57,58)(H,63,64)/t28-,29-,36+,37-,38+,41+,42+/m1/s1	KHLJXSVWOGJLNX-PLWYTWDASA-N	50281579	(S)-3-{2-[((R)-2-Acetylamino-3-phenyl-propionyl)-benzyl-amino]-acetylamino}-N-((1S,2R)-1-{(1S,2R)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL148751	Endothelin-1 receptor			 30							ChEMBL	10.1016/S0960-894X(01)81219-1	10.7270/Q27081C5				Spellmeyer, DC; Brown, S; Stauber, GB; Geysen, H; Valerio, R	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281579&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44365954	104123253		CHEMBL148751					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466098	CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H60N8O11/c1-6-23(3)36(41(59)49-34(43(61)62)20-27-22-45-30-12-9-8-11-29(27)30)51-42(60)37(24(4)7-2)50-40(58)33(21-35(54)55)48-38(56)31(13-10-18-44)47-39(57)32(46-25(5)52)19-26-14-16-28(53)17-15-26/h8-9,11-12,14-17,22-24,31-34,36-37,45,53H,6-7,10,13,18-21,44H2,1-5H3,(H,46,52)(H,47,57)(H,48,56)(H,49,59)(H,50,58)(H,51,60)(H,54,55)(H,61,62)/t23-,24-,31+,32-,33+,34+,36+,37+/m1/s1	HDCVHSOSPSFMCT-RNPQISIMSA-N	50281577	(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-5-amino-pentanoylamino}-N-((1S,2R)-1-{(1S,2R)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL147510	Endothelin-1 receptor			 400							ChEMBL	10.1016/S0960-894X(01)81219-1	10.7270/Q27081C5				Spellmeyer, DC; Brown, S; Stauber, GB; Geysen, H; Valerio, R	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281577&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44366059	104123251		CHEMBL147510					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50466104	CC[C@H](C)[C@@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H57N7O10/c1-6-24(3)36(40(56)47-33(43(59)60)21-28-23-44-30-17-12-11-16-29(28)30)49-41(57)37(25(4)7-2)48-38(54)31(22-35(52)53)46-39(55)34-18-13-19-50(34)42(58)32(45-26(5)51)20-27-14-9-8-10-15-27/h8-12,14-17,23-25,31-34,36-37,44H,6-7,13,18-22H2,1-5H3,(H,45,51)(H,46,55)(H,47,56)(H,48,54)(H,49,57)(H,52,53)(H,59,60)/t24-,25-,31+,32+,33+,34+,36+,37+/m0/s1	DEJOFTGYMOOOMQ-XHOJCBQOSA-N	50281586	(R)-3-{[(R)-1-((R)-2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-N-((1R,2S)-1-{(1R,2S)-1-[(R)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL347948	Endothelin-1 receptor			 15							ChEMBL	10.1016/S0960-894X(01)81219-1	10.7270/Q27081C5				Spellmeyer, DC; Brown, S; Stauber, GB; Geysen, H; Valerio, R	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281586&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44366010	104123260		CHEMBL347948				ZINC95612037	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480076	O=C(OCc1ccc2OCOc2c1)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C30H21NO6/c32-30(33-15-18-9-11-24-26(13-18)36-16-34-24)28(19-10-12-25-27(14-19)37-17-35-25)29-20-5-1-3-7-22(20)31-23-8-4-2-6-21(23)29/h1-14,28H,15-17H2	WDCUHHNJZSWUFN-UHFFFAOYSA-N	50288539	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid benzo[1,3]dioxol-5-ylmethyl ester::CHEMBL316648	Endothelin-1 receptor			 8700							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288539&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332546	104130110		CHEMBL316648				ZINC26751656	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476175	[Na+].CCCC[C@@H](NC(=O)[C@@H](Cc1cn(COC)c2ccccc12)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C([O-])=O	InChI=1S/C34H53N5O6/c1-8-9-16-26(32(42)43)35-30(40)27(18-24-20-38(21-45-7)29-17-11-10-15-25(24)29)36-31(41)28(19-34(4,5)6)37-33(44)39-22(2)13-12-14-23(39)3/h10-11,15,17,20,22-23,26-28H,8-9,12-14,16,18-19,21H2,1-7H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/p-1	VUMPRRVUQQKTMC-UHFFFAOYSA-M	50286614	CHEMBL155943::CHEMBL3143473::Sodium; 2-[2-{2-[(2,6-dimethyl-piperidine-1-carbonyl)-amino]-4,4-dimethyl-pentanoylamino}-3-(1-methoxymethyl-1H-indol-3-yl)-propionylamino]-hexanoate	Endothelin-1 receptor			 1300							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286614&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			90663476	104128185		CHEMBL3143473CHEMBL155943				ZINC36247996	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476178	N[C@@H](C1c2ccccc2CCc2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C59H60N8O10/c60-51(70)32-49(65-55(72)48(28-34-10-2-1-3-11-34)66-58(75)53(61)52-43-15-6-4-12-37(43)22-23-38-13-5-7-16-44(38)52)57(74)64-46(29-35-18-24-40(68)25-19-35)54(71)63-47(30-36-20-26-41(69)27-21-36)56(73)67-50(59(76)77)31-39-33-62-45-17-9-8-14-42(39)45/h1-21,24-27,33,46-50,52-53,62,68-69H,22-23,28-32,61H2,(H2,60,70)(H,63,71)(H,64,74)(H,65,72)(H,66,75)(H,67,73)(H,76,77)/t46-,47-,48-,49-,50-,53-/m0/s1	ODHKJPGCAWIPPT-ZQJLCUDRSA-N	50286617	CHEMBL414917::bhg-F-N-Y-Y-W	Endothelin-1 receptor			 9500							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371614	104128188		CHEMBL414917					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476179	C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)CN)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C103H117N23O24/c1-54(113-101(147)89(55(2)127)125-87(133)52-111-90(136)78(43-63-51-107-53-112-63)121-96(142)77(41-61-49-109-70-24-13-10-21-67(61)70)119-97(143)79(44-84(105)130)114-86(132)47-104)102(148)126-35-15-26-83(126)100(146)123-81(46-88(134)135)99(145)120-76(40-60-48-108-69-23-12-9-20-66(60)69)95(141)117-72(36-56-16-5-3-6-17-56)91(137)115-73(37-57-18-7-4-8-19-57)93(139)122-80(45-85(106)131)98(144)118-74(38-58-27-31-64(128)32-28-58)92(138)116-75(39-59-29-33-65(129)34-30-59)94(140)124-82(103(149)150)42-62-50-110-71-25-14-11-22-68(62)71/h3-14,16-25,27-34,48-51,53-55,72-83,89,108-110,127-129H,15,26,35-47,52,104H2,1-2H3,(H2,105,130)(H2,106,131)(H,107,112)(H,111,136)(H,113,147)(H,114,132)(H,115,137)(H,116,138)(H,117,141)(H,118,144)(H,119,143)(H,120,145)(H,121,142)(H,122,139)(H,123,146)(H,124,140)(H,125,133)(H,134,135)(H,149,150)/t54-,55+,72-,73-,74-,75-,76-,77-,78-,79-,80-,81+,82-,83+,89-/m0/s1	ZUENRBCVCNXGQC-RSJDORCSSA-N	50286616	CHEMBL267610::G-N-W-H-G-T-A-P-D-W-F-F-N-Y-Y-W	Endothelin-1 receptor			>2500							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286616&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91934865	104128187		CHEMBL267610					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476180	NC(=O)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C62H63N9O12/c63-55(74)33-52(70-58(77)49(28-37-13-5-2-6-14-37)67-56(75)48(27-36-11-3-1-4-12-36)66-53(61(80)81)31-40-34-64-46-17-9-7-15-44(40)46)60(79)69-50(29-38-19-23-42(72)24-20-38)57(76)68-51(30-39-21-25-43(73)26-22-39)59(78)71-54(62(82)83)32-41-35-65-47-18-10-8-16-45(41)47/h1-26,34-35,48-54,64-66,72-73H,27-33H2,(H2,63,74)(H,67,75)(H,68,76)(H,69,79)(H,70,77)(H,71,78)(H,80,81)(H,82,83)/t48-,49-,50-,51-,52-,53+,54-/m0/s1	NXCOTRHNIBGFLM-ZYWWURNJSA-N	50286618	CHEMBL413880::W-F-F-N--Y-Y-W	Endothelin-1 receptor			 2400							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286618&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371672	104128189		CHEMBL413880					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476184	CC(=O)N[C@@H](C1c2ccccc2CCc2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C61H62N8O11/c1-35(70)64-55(54-45-16-7-5-13-39(45)23-24-40-14-6-8-17-46(40)54)60(78)68-50(29-36-11-3-2-4-12-36)57(75)67-51(33-53(62)73)59(77)66-48(30-37-19-25-42(71)26-20-37)56(74)65-49(31-38-21-27-43(72)28-22-38)58(76)69-52(61(79)80)32-41-34-63-47-18-10-9-15-44(41)47/h2-22,25-28,34,48-52,54-55,63,71-72H,23-24,29-33H2,1H3,(H2,62,73)(H,64,70)(H,65,74)(H,66,77)(H,67,75)(H,68,78)(H,69,76)(H,79,80)/t48-,49-,50-,51-,52-,55-/m0/s1	DTNUUCGDOGDUBL-NHTZSVLLSA-N	50286619	Ac-bhg-F-N-Y-Y-W::CHEMBL385405	Endothelin-1 receptor			 1900							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286619&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371670	104128190		CHEMBL385405					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476189	N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H54N8O10/c52-38(23-30-9-3-1-4-10-30)46(63)55-40(24-31-11-5-2-6-12-31)47(64)58-43(28-45(53)62)50(67)57-41(25-32-15-19-35(60)20-16-32)48(65)56-42(26-33-17-21-36(61)22-18-33)49(66)59-44(51(68)69)27-34-29-54-39-14-8-7-13-37(34)39/h1-22,29,38,40-44,54,60-61H,23-28,52H2,(H2,53,62)(H,55,63)(H,56,65)(H,57,67)(H,58,64)(H,59,66)(H,68,69)/t38-,40-,41-,42-,43-,44-/m0/s1	BPHGVBPWTSMGDX-HAKKBKSLSA-N	50286621	CHEMBL264253::F-F-N-Y-YW	Endothelin-1 receptor			>25000							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286621&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371612	104128192		CHEMBL264253					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476190	CC(=O)[C@@H](Cc1c[nH]c2ccccc12)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C63H65N9O11/c1-37(73)50(32-42-35-65-48-18-10-8-16-46(42)48)67-51(28-38-12-4-2-5-13-38)58(77)68-52(29-39-14-6-3-7-15-39)60(79)71-55(34-57(64)76)62(81)70-53(30-40-20-24-44(74)25-21-40)59(78)69-54(31-41-22-26-45(75)27-23-41)61(80)72-56(63(82)83)33-43-36-66-49-19-11-9-17-47(43)49/h2-27,35-36,50-56,65-67,74-75H,28-34H2,1H3,(H2,64,76)(H,68,77)(H,69,78)(H,70,81)(H,71,79)(H,72,80)(H,82,83)/t50-,51+,52+,53+,54+,55+,56+/m1/s1	JNMRBSLUOYEORH-GMXKVRHKSA-N	50286622	Ac-W-F-F-N-Y-Y-W::CHEMBL405677	Endothelin-1 receptor			 250							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286622&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371613	104128193		CHEMBL405677					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476191	CC(=O)[C@H](Cc1c[nH]c2ccccc12)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C63H65N9O11/c1-37(73)50(32-42-35-65-48-18-10-8-16-46(42)48)67-51(28-38-12-4-2-5-13-38)58(77)68-52(29-39-14-6-3-7-15-39)60(79)71-55(34-57(64)76)62(81)70-53(30-40-20-24-44(74)25-21-40)59(78)69-54(31-41-22-26-45(75)27-23-41)61(80)72-56(63(82)83)33-43-36-66-49-19-11-9-17-47(43)49/h2-27,35-36,50-56,65-67,74-75H,28-34H2,1H3,(H2,64,76)(H,68,77)(H,69,78)(H,70,81)(H,71,79)(H,72,80)(H,82,83)/t50-,51-,52-,53-,54-,55-,56-/m0/s1	JNMRBSLUOYEORH-LNZSLCJFSA-N	50286615	Ac-w-F-F-N-Y-Y-W::CHEMBL441006	Endothelin-1 receptor			 8100							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286615&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44371671	104128186		CHEMBL441006					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476193	C[C@@H](O)[C@H]1NC(=O)CNC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC1=O	InChI=1S/C103H115N23O23/c1-54-102(147)126-35-15-26-83(126)100(145)123-81(91(136)110-51-87(133)115-79(44-84(104)130)98(143)120-77(41-61-48-108-70-24-13-10-21-67(61)70)97(142)121-78(43-63-50-106-53-112-63)90(135)111-52-88(134)125-89(55(2)127)101(146)113-54)46-86(132)114-76(40-60-47-107-69-23-12-9-20-66(60)69)96(141)118-72(36-56-16-5-3-6-17-56)92(137)116-73(37-57-18-7-4-8-19-57)94(139)122-80(45-85(105)131)99(144)119-74(38-58-27-31-64(128)32-28-58)93(138)117-75(39-59-29-33-65(129)34-30-59)95(140)124-82(103(148)149)42-62-49-109-71-25-14-11-22-68(62)71/h3-14,16-25,27-34,47-50,53-55,72-83,89,107-109,127-129H,15,26,35-46,51-52H2,1-2H3,(H2,104,130)(H2,105,131)(H,106,112)(H,110,136)(H,111,135)(H,113,146)(H,114,132)(H,115,133)(H,116,137)(H,117,138)(H,118,141)(H,119,144)(H,120,143)(H,121,142)(H,122,139)(H,123,145)(H,124,140)(H,125,134)(H,148,149)/t54-,55+,72-,73-,74-,75-,76-,77-,78+,79+,80-,81-,82-,83+,89+/m0/s1	VWFLFTLWXQPVNV-SYUZYMOHSA-N	50286613	CHEMBL413825::Cyclic (Gly1-Asp9) (Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp)	Endothelin-1 receptor			 7800							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286613&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91934863	104128184		CHEMBL413825					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476194	C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C97H108N20O21/c1-52(106-95(135)84(53(2)118)116-82(122)50-104-86(126)76(43-61-49-100-51-105-61)107-85(125)67(98)40-58-46-101-68-23-12-9-20-64(58)68)96(136)117-35-15-26-80(117)94(134)114-78(45-83(123)124)93(133)112-75(41-59-47-102-69-24-13-10-21-65(59)69)91(131)110-71(36-54-16-5-3-6-17-54)87(127)108-72(37-55-18-7-4-8-19-55)89(129)113-77(44-81(99)121)92(132)111-73(38-56-27-31-62(119)32-28-56)88(128)109-74(39-57-29-33-63(120)34-30-57)90(130)115-79(97(137)138)42-60-48-103-70-25-14-11-22-66(60)70/h3-14,16-25,27-34,46-49,51-53,67,71-80,84,101-103,118-120H,15,26,35-45,50,98H2,1-2H3,(H2,99,121)(H,100,105)(H,104,126)(H,106,135)(H,107,125)(H,108,127)(H,109,128)(H,110,131)(H,111,132)(H,112,133)(H,113,129)(H,114,134)(H,115,130)(H,116,122)(H,123,124)(H,137,138)/t52-,53+,67-,71-,72-,73-,74-,75-,76-,77-,78+,79-,80+,84-/m0/s1	IBUFWKNLBVXBHS-SIGCDQPFSA-N	50286620	CHEMBL415614::W-H-G-T-A-P-D-W-F-F-N-Y-Y-W	Endothelin-1 receptor			>2500							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286620&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91934866	104128191		CHEMBL415614					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479436	Cc1noc(NS(=O)(=O)c2sccc2-c2ccccc2)c1Br	InChI=1S/C14H11BrN2O3S2/c1-9-12(15)13(20-16-9)17-22(18,19)14-11(7-8-21-14)10-5-3-2-4-6-10/h2-8,17H,1H3	XEAVSGOYZRKLQG-UHFFFAOYSA-N	50288261	3-Phenyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL88506	Endothelin-1 receptor			 819							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288261&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445388	104129832		CHEMBL88506				ZINC26579259	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479437	Cc1noc(NS(=O)(=O)c2sccc2Oc2ccccc2)c1Br	InChI=1S/C14H11BrN2O4S2/c1-9-12(15)13(21-16-9)17-23(18,19)14-11(7-8-22-14)20-10-5-3-2-4-6-10/h2-8,17H,1H3	CHSJDJZZUJFWQS-UHFFFAOYSA-N	50288262	3-Phenoxy-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL89457	Endothelin-1 receptor			 1450							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998447	104129833		CHEMBL89457				ZINC26578831	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479439	Cc1noc(NS(=O)(=O)c2sccc2Cc2ccccc2)c1Br	InChI=1S/C15H13BrN2O3S2/c1-10-13(16)14(21-17-10)18-23(19,20)15-12(7-8-22-15)9-11-5-3-2-4-6-11/h2-8,18H,9H2,1H3	XTLWXRWZKDAMBY-UHFFFAOYSA-N	50288264	3-Benzyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL92318	Endothelin-1 receptor			 2603							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445254	104129835		CHEMBL92318				ZINC26638939	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479440	CCCCc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C18H19BrN2O3S2/c1-3-4-5-13-6-8-14(9-7-13)15-10-11-25-18(15)26(22,23)21-17-16(19)12(2)20-24-17/h6-11,21H,3-5H2,1-2H3	KOUFSJACWKYFBC-UHFFFAOYSA-N	50288265	3-(4-Butyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL329560	Endothelin-1 receptor			 160							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445285	104129836		CHEMBL329560				ZINC26579103	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479441	Cc1noc(NS(=O)(=O)c2sccc2-c2cccc(C)c2)c1Br	InChI=1S/C15H13BrN2O3S2/c1-9-4-3-5-11(8-9)12-6-7-22-15(12)23(19,20)18-14-13(16)10(2)17-21-14/h3-8,18H,1-2H3	XEGNVAZBTXEYFA-UHFFFAOYSA-N	50288266	3-m-Tolyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL328089	Endothelin-1 receptor			 832							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445358	104129837		CHEMBL328089				ZINC26638934	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479442	CC(C)CCc1ccc(-c2ccsc2S(=O)(=O)Nc2onc(C)c2Br)c(C)c1	InChI=1S/C20H23BrN2O3S2/c1-12(2)5-6-15-7-8-16(13(3)11-15)17-9-10-27-20(17)28(24,25)23-19-18(21)14(4)22-26-19/h7-12,23H,5-6H2,1-4H3	WPTQKSYKUZJMAC-UHFFFAOYSA-N	50288260	3-[2-Methyl-4-(3-methyl-butyl)-phenyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL313801	Endothelin-1 receptor			 115							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445366	104129831		CHEMBL313801				ZINC26579663	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479443	COc1cccc(c1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C15H13BrN2O4S2/c1-9-13(16)14(22-17-9)18-24(19,20)15-12(6-7-23-15)10-4-3-5-11(8-10)21-2/h3-8,18H,1-2H3	XOPBZFBTFZYQOC-UHFFFAOYSA-N	50288267	3-(3-Methoxy-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL329861	Endothelin-1 receptor			 1320							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445219	104129838		CHEMBL329861				ZINC26578581	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479446	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2)c1Br	InChI=1S/C16H13BrN2O3S/c1-11-15(17)16(22-18-11)19-23(20,21)14-10-6-5-9-13(14)12-7-3-2-4-8-12/h2-10,19H,1H3	JNBSJLZGQLLABB-UHFFFAOYSA-N	50288038	Biphenyl-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL80857	Endothelin-1 receptor			 16							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288038&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453177	104129609		CHEMBL80857				ZINC01540808	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479448	Cc1noc(NS(=O)(=O)c2sccc2-c2ccc(C)cc2)c1Br	InChI=1S/C15H13BrN2O3S2/c1-9-3-5-11(6-4-9)12-7-8-22-15(12)23(19,20)18-14-13(16)10(2)17-21-14/h3-8,18H,1-2H3	LTECCECZZZMLGF-UHFFFAOYSA-N	50288271	3-p-Tolyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL91073	Endothelin-1 receptor			 316							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288271&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998508	104129842		CHEMBL91073				ZINC26640704	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479452	CC(C)CCc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C19H21BrN2O3S2/c1-12(2)4-5-14-6-8-15(9-7-14)16-10-11-26-19(16)27(23,24)22-18-17(20)13(3)21-25-18/h6-12,22H,4-5H2,1-3H3	ZEXCTKKHUJWXNG-UHFFFAOYSA-N	50288273	3-[4-(3-Methyl-butyl)-phenyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL314307	Endothelin-1 receptor			 182							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288273&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445516	104129844		CHEMBL314307				ZINC26579101	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479453	Cc1noc(NS(=O)(=O)c2sccc2-c2ccc(C)cc2C)c1Br	InChI=1S/C16H15BrN2O3S2/c1-9-4-5-12(10(2)8-9)13-6-7-23-16(13)24(20,21)19-15-14(17)11(3)18-22-15/h4-8,19H,1-3H3	RAYIQSXQPBGDMP-UHFFFAOYSA-N	50288263	3-(2,4-Dimethyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL89688	Endothelin-1 receptor			 100							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445498	104129834		CHEMBL89688				ZINC26579102	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479454	COc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C15H13BrN2O4S2/c1-9-13(16)14(22-17-9)18-24(19,20)15-12(7-8-23-15)10-3-5-11(21-2)6-4-10/h3-8,18H,1-2H3	UMYXMQATBDTKTB-UHFFFAOYSA-N	50288274	3-(4-Methoxy-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL89689	Endothelin-1 receptor			 334							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288274&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44322947	104129845		CHEMBL89689				ZINC26578579	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479456	CC(C)Cc1ccc(-c2ccsc2S(=O)(=O)Nc2onc(C)c2Br)c(C)c1	InChI=1S/C19H21BrN2O3S2/c1-11(2)9-14-5-6-15(12(3)10-14)16-7-8-26-19(16)27(23,24)22-18-17(20)13(4)21-25-18/h5-8,10-11,22H,9H2,1-4H3	AWUGISSFNNESFD-UHFFFAOYSA-N	50288275	3-(4-Isobutyl-2-methyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL432815	Endothelin-1 receptor			 48							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288275&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445250	104129846		CHEMBL432815				ZINC26579026	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479457	Cc1noc(NS(=O)(=O)c2ccc(s2)-c2ccccc2)c1Br	InChI=1S/C14H11BrN2O3S2/c1-9-13(15)14(20-16-9)17-22(18,19)12-8-7-11(21-12)10-5-3-2-4-6-10/h2-8,17H,1H3	WJYHCMUTAFRGIX-UHFFFAOYSA-N	50288259	5-Phenyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL314320	Endothelin-1 receptor			 36600							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288259&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998446	104129830		CHEMBL314320				ZINC26579417	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479458	Cc1noc(NS(=O)(=O)c2cccs2)c1Br	InChI=1S/C8H7BrN2O3S2/c1-5-7(9)8(14-10-5)11-16(12,13)6-3-2-4-15-6/h2-4,11H,1H3	JKEYACSIUDERBP-UHFFFAOYSA-N	50288276	CHEMBL91470::Thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide	Endothelin-1 receptor			 1910							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288276&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15342056	104129847		CHEMBL91470				ZINC26641864	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479459	Cc1noc(NS(=O)(=O)c2cc(cs2)-c2ccccc2)c1Br	InChI=1S/C14H11BrN2O3S2/c1-9-13(15)14(20-16-9)17-22(18,19)12-7-11(8-21-12)10-5-3-2-4-6-10/h2-8,17H,1H3	NXWRCHOPXGTIMB-UHFFFAOYSA-N	50288272	4-Phenyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL329375	Endothelin-1 receptor			 3390							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288272&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445547	104129843		CHEMBL329375				ZINC26578971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479460	CCCc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C17H17BrN2O3S2/c1-3-4-12-5-7-13(8-6-12)14-9-10-24-17(14)25(21,22)20-16-15(18)11(2)19-23-16/h5-10,20H,3-4H2,1-2H3	LNLVEJQUXLDABL-UHFFFAOYSA-N	50288277	3-(4-Propyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL329890	Endothelin-1 receptor			 87							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288277&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10275056	104129848		CHEMBL329890				ZINC26640676	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479462	Cc1noc(NS(=O)(=O)c2ccsc2)c1Br	InChI=1S/C8H7BrN2O3S2/c1-5-7(9)8(14-10-5)11-16(12,13)6-2-3-15-4-6/h2-4,11H,1H3	DYJPRYOZZBRIGG-UHFFFAOYSA-N	50288269	CHEMBL265290::Thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide	Endothelin-1 receptor			 2750							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288269&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			12146375	104129840		CHEMBL265290				ZINC13815541	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479466	CC(C)Cc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C18H19BrN2O3S2/c1-11(2)10-13-4-6-14(7-5-13)15-8-9-25-18(15)26(22,23)21-17-16(19)12(3)20-24-17/h4-9,11,21H,10H2,1-3H3	ISOVASWMWBKCEN-UHFFFAOYSA-N	50288280	3-(4-Isobutyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL328517	Endothelin-1 receptor			 82							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288280&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445408	104129851		CHEMBL328517				ZINC26578970	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479468	Cc1noc(NS(=O)(=O)c2sccc2-c2ccccc2C)c1Br	InChI=1S/C15H13BrN2O3S2/c1-9-5-3-4-6-11(9)12-7-8-22-15(12)23(19,20)18-14-13(16)10(2)17-21-14/h3-8,18H,1-2H3	QCWFHRALODUOMA-UHFFFAOYSA-N	50288270	3-o-Tolyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL313551	Endothelin-1 receptor			 306							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288270&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445410	104129841		CHEMBL313551				ZINC26579178	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479469	CC(C)c1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C17H17BrN2O3S2/c1-10(2)12-4-6-13(7-5-12)14-8-9-24-17(14)25(21,22)20-16-15(18)11(3)19-23-16/h4-10,20H,1-3H3	QDXPMETWGQNDRO-UHFFFAOYSA-N	50288281	3-(4-Isopropyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL330674	Endothelin-1 receptor			 218							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288281&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445284	104129852		CHEMBL330674				ZINC26578911	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479470	CCc1ccc(cc1)-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C16H15BrN2O3S2/c1-3-11-4-6-12(7-5-11)13-8-9-23-16(13)24(20,21)19-15-14(17)10(2)18-22-15/h4-9,19H,3H2,1-2H3	MDEAKQNDFNTWOV-UHFFFAOYSA-N	50288268	3-(4-Ethyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL89203	Endothelin-1 receptor			 184							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288268&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445354	104129839		CHEMBL89203				ZINC26578912	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479473	Cc1noc(NS(=O)(=O)c2ccsc2-c2ccccc2)c1Br	InChI=1S/C14H11BrN2O3S2/c1-9-12(15)14(20-16-9)17-22(18,19)11-7-8-21-13(11)10-5-3-2-4-6-10/h2-8,17H,1H3	XBCZCJQNBKILNP-UHFFFAOYSA-N	50288279	2-Phenyl-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL293232	Endothelin-1 receptor			 603							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288279&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998396	104129850		CHEMBL293232				ZINC13815562	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479475	COc1ccccc1-c1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C15H13BrN2O4S2/c1-9-13(16)14(22-17-9)18-24(19,20)15-11(7-8-23-15)10-5-3-4-6-12(10)21-2/h3-8,18H,1-2H3	YNQQSADOYDWEGK-UHFFFAOYSA-N	50288278	3-(2-Methoxy-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL330003	Endothelin-1 receptor			 1710							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288278&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445506	104129849		CHEMBL330003				ZINC26640699	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479479	CCCc1ccc(-c2ccsc2S(=O)(=O)Nc2onc(C)c2Br)c(C)c1	InChI=1S/C18H19BrN2O3S2/c1-4-5-13-6-7-14(11(2)10-13)15-8-9-25-18(15)26(22,23)21-17-16(19)12(3)20-24-17/h6-10,21H,4-5H2,1-3H3	RQMRNWJRXJVROO-UHFFFAOYSA-N	50288282	3-(2-Methyl-4-propyl-phenyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL316012	Endothelin-1 receptor			 43							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288282&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10366742	104129853		CHEMBL316012				ZINC26579666	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479482	Cc1noc(NS(=O)(=O)c2ccccc2)c1Br	InChI=1S/C10H9BrN2O3S/c1-7-9(11)10(16-12-7)13-17(14,15)8-5-3-2-4-6-8/h2-6,13H,1H3	WAIXPTZIWAKDPT-UHFFFAOYSA-N	50288024	CHEMBL78080::N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide	Endothelin-1 receptor			 2510							ChEMBL	10.1016/S0960-894X(96)00496-9	10.7270/Q24M94HV				Raju, B; Wu, C; Kois, A; Verner, E; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288024&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617288	104129595		CHEMBL78080				ZINC26484753	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480686	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C109H159N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80-49-169-168-48-64(111)89(145)126-77(45-135)102(158)131-81-50-170-171-51-82(105(161)132-86(55(7)8)106(162)124-72(38-59-26-28-62(138)29-27-59)95(151)120-71(96(152)130-80)37-58-21-15-14-16-22-58)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-167-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(81)160/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,86-,87-,88-/m0/s1	ZUBDGKVDJUIMQQ-ZTNLKOGPSA-N	50155246	CHEMBL3775234	Endothelin-1 receptor			 0.023							ChEMBL	10.1016/j.bmc.2016.03.006	10.7270/Q2J67JS7	26988801			Waszkielewicz, AM; Gunia-Krzyzak, A; Powroznik, B; Sloczynska, K; Pekala, E; Walczak, M; Bednarski, M; Zeslawska, E; Nitek, W; Marona, H	Jagiellonian University Medical College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155246&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16212950	340133542		CHEMBL3775234					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477389	COc1cccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OCc4ccccc4)c(OC)cc23)c1	InChI=1S/C32H27NO7S/c1-36-22-9-6-10-23(14-22)41-31-24-15-27(37-2)29(38-18-20-7-4-3-5-8-20)16-25(24)33(30(31)32(34)35)17-21-11-12-26-28(13-21)40-19-39-26/h3-16H,17-19H2,1-2H3,(H,34,35)	OUYVTZBZGJXGRX-UHFFFAOYSA-N	50287181	1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL285380	Endothelin-1 receptor			 20000							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287181&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44278161	104128752		CHEMBL285380				ZINC28770629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477394	COc1cccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OC)c(OCc4ccccc4)cc23)c1	InChI=1S/C32H27NO7S/c1-36-22-9-6-10-23(14-22)41-31-24-15-29(38-18-20-7-4-3-5-8-20)27(37-2)16-25(24)33(30(31)32(34)35)17-21-11-12-26-28(13-21)40-19-39-26/h3-16H,17-19H2,1-2H3,(H,34,35)	NIGCNIFGPYTDPJ-UHFFFAOYSA-N	50287185	1-Benzo[1,3]dioxol-5-ylmethyl-5-benzyloxy-6-methoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL281451	Endothelin-1 receptor			 81							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287185&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995996	104128756		CHEMBL281451				ZINC28769130	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477397	COc1cccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OC)c(OC)cc23)c1	InChI=1S/C26H23NO7S/c1-30-16-5-4-6-17(10-16)35-25-18-11-21(31-2)22(32-3)12-19(18)27(24(25)26(28)29)13-15-7-8-20-23(9-15)34-14-33-20/h4-12H,13-14H2,1-3H3,(H,28,29)	XPUJKHFCHQYTEQ-UHFFFAOYSA-N	50287186	1-Benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL285368	Endothelin-1 receptor			 20							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287186&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15289330	104128757		CHEMBL285368				ZINC28769213	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477401	COc1cc(Cn2c(C(O)=O)c(Sc3ccc(OC)c(OC)c3)c3cc4OCOc4cc23)cc2OCOc12	InChI=1S/C27H23NO9S/c1-31-18-5-4-15(8-19(18)32-2)38-26-16-9-20-21(35-12-34-20)10-17(16)28(24(26)27(29)30)11-14-6-22(33-3)25-23(7-14)36-13-37-25/h4-10H,11-13H2,1-3H3,(H,29,30)	MRISGPUEHMXCRJ-UHFFFAOYSA-N	50287191	7-(3,4-Dimethoxy-phenylsulfanyl)-5-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL283858	Endothelin-1 receptor			 170							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287191&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995986	104128762		CHEMBL283858				ZINC28769805	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477403	COc1cc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OCc4ccccc4)c(OC)cc23)cc(OC)c1OC	InChI=1S/C34H31NO9S/c1-38-26-15-23-24(16-28(26)42-18-20-8-6-5-7-9-20)35(17-21-10-11-25-27(12-21)44-19-43-25)31(34(36)37)33(23)45-22-13-29(39-2)32(41-4)30(14-22)40-3/h5-16H,17-19H2,1-4H3,(H,36,37)	UWDFQTODSZRCKT-UHFFFAOYSA-N	50287193	1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-3-(3,4,5-trimethoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL435568	Endothelin-1 receptor			>2500							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287193&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995995	104128764		CHEMBL435568				ZINC28770448	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477404	COc1cccc(Sc2c(C(O)=O)n(Cc3ccccc3)c3ccccc23)c1	InChI=1S/C23H19NO3S/c1-27-17-10-7-11-18(14-17)28-22-19-12-5-6-13-20(19)24(21(22)23(25)26)15-16-8-3-2-4-9-16/h2-14H,15H2,1H3,(H,25,26)	PSDFJKFTKVCJJB-UHFFFAOYSA-N	50287189	1-Benzyl-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL28948	Endothelin-1 receptor			 4600							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287189&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995988	104128760		CHEMBL28948				ZINC28770535	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477408	COc1cccc(Sc2c(C(O)=O)n(Cc3cc4OCOc4c(OC)c3)c3cc(OC)c(OC)cc23)c1	InChI=1S/C27H25NO8S/c1-31-16-6-5-7-17(10-16)37-26-18-11-20(32-2)21(33-3)12-19(18)28(24(26)27(29)30)13-15-8-22(34-4)25-23(9-15)35-14-36-25/h5-12H,13-14H2,1-4H3,(H,29,30)	MNLRNQODLJLCSB-UHFFFAOYSA-N	50287194	5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL416570	Endothelin-1 receptor			 58							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287194&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995998	104128765		CHEMBL416570				ZINC28769926	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477409	CCCOc1ccc2c(Sc3cccc(OC)c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2c1	InChI=1S/C27H25NO6S/c1-3-11-32-19-8-9-21-22(14-19)28(15-17-7-10-23-24(12-17)34-16-33-23)25(27(29)30)26(21)35-20-6-4-5-18(13-20)31-2/h4-10,12-14H,3,11,15-16H2,1-2H3,(H,29,30)	TWYHKSBHPXEEHI-UHFFFAOYSA-N	50287192	1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenylsulfanyl)-6-propoxy-1H-indole-2-carboxylic acid::CHEMBL282398	Endothelin-1 receptor			 590							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287192&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18996000	104128763		CHEMBL282398				ZINC28769261	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477414	COc1cc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc4OCOc4cc23)cc(OC)c1OC	InChI=1S/C27H23NO9S/c1-31-22-7-15(8-23(32-2)25(22)33-3)38-26-16-9-20-21(37-13-36-20)10-17(16)28(24(26)27(29)30)11-14-4-5-18-19(6-14)35-12-34-18/h4-10H,11-13H2,1-3H3,(H,29,30)	FDDMPZZHBROSPE-UHFFFAOYSA-N	50287190	5-Benzo[1,3]dioxol-5-ylmethyl-7-(3,4,5-trimethoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL28920	Endothelin-1 receptor			 7							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287190&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995991	104128761		CHEMBL28920				ZINC28769104	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477416	OC(=O)c1c(Sc2ccc3OCOc3c2)c2ccccc2n1Cc1ccc2OCOc2c1	InChI=1S/C24H17NO6S/c26-24(27)22-23(32-15-6-8-19-21(10-15)31-13-29-19)16-3-1-2-4-17(16)25(22)11-14-5-7-18-20(9-14)30-12-28-18/h1-10H,11-13H2,(H,26,27)	LTMNIPISSYOICK-UHFFFAOYSA-N	50287195	1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL28779	Endothelin-1 receptor			 380							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287195&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10160887	104128766		CHEMBL28779				ZINC28770470	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477418	COc1cccc(Sc2c(C(O)=O)n(Cc3ccccc3)c3cc(OC)c(OC)cc23)c1	InChI=1S/C25H23NO5S/c1-29-17-10-7-11-18(12-17)32-24-19-13-21(30-2)22(31-3)14-20(19)26(23(24)25(27)28)15-16-8-5-4-6-9-16/h4-14H,15H2,1-3H3,(H,27,28)	OGGZHZAVIHOULX-UHFFFAOYSA-N	50287199	1-Benzyl-5,6-dimethoxy-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL28188	Endothelin-1 receptor			 160							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287199&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44278003	104128770		CHEMBL28188				ZINC28769772	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477423	COc1cccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3ccccc23)c1	InChI=1S/C24H19NO5S/c1-28-16-5-4-6-17(12-16)31-23-18-7-2-3-8-19(18)25(22(23)24(26)27)13-15-9-10-20-21(11-15)30-14-29-20/h2-12H,13-14H2,1H3,(H,26,27)	KEJQXHVQMSWRIM-UHFFFAOYSA-N	50287198	1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL283648	Endothelin-1 receptor			 86							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287198&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15289331	104128769		CHEMBL283648				ZINC28770533	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477426	COc1cccc(Sc2c(sc3ccccc23)C(O)=O)c1	InChI=1S/C16H12O3S2/c1-19-10-5-4-6-11(9-10)20-14-12-7-2-3-8-13(12)21-15(14)16(17)18/h2-9H,1H3,(H,17,18)	MDZYCFGFUYNVSV-UHFFFAOYSA-N	50287188	3-(3-Methoxy-phenylsulfanyl)-benzo[b]thiophene-2-carboxylic acid::CHEMBL27911	Endothelin-1 receptor			 5900							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287188&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19347988	104128759		CHEMBL27911				ZINC28769795	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477428	COc1cccc(Sc2c(oc3ccccc23)C(O)=O)c1	InChI=1S/C16H12O4S/c1-19-10-5-4-6-11(9-10)21-15-12-7-2-3-8-13(12)20-14(15)16(17)18/h2-9H,1H3,(H,17,18)	JFCHYHCFMYNCBT-UHFFFAOYSA-N	50287184	3-(3-Methoxy-phenylsulfanyl)-benzofuran-2-carboxylic acid::CHEMBL416019	Endothelin-1 receptor			 23000							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287184&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44278270	104128755		CHEMBL416019				ZINC28770398	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477434	COc1cccc(Sc2c(C(O)=O)n(Cc3cc4OCOc4c(OC)c3)c3cc4OCOc4cc23)c1	InChI=1S/C26H21NO8S/c1-30-15-4-3-5-16(8-15)36-25-17-9-19-20(33-12-32-19)10-18(17)27(23(25)26(28)29)11-14-6-21(31-2)24-22(7-14)34-13-35-24/h3-10H,11-13H2,1-2H3,(H,28,29)	GHQLZFCVPBBGLP-UHFFFAOYSA-N	50287201	5-(7-Methoxy-benzo[1,3]dioxol-5-ylmethyl)-7-(3-methoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL282426	Endothelin-1 receptor			 380							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287201&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995990	104128772		CHEMBL282426				ZINC28771337	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477435	COc1cc2c(Sc3ccc4OCOc4c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OC	InChI=1S/C26H21NO8S/c1-30-20-9-16-17(10-21(20)31-2)27(11-14-3-5-18-22(7-14)34-12-32-18)24(26(28)29)25(16)36-15-4-6-19-23(8-15)35-13-33-19/h3-10H,11-13H2,1-2H3,(H,28,29)	NQDCDWVUSPOECA-UHFFFAOYSA-N	50287183	1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL27732	Endothelin-1 receptor			 5							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287183&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9957883	104128754		CHEMBL27732				ZINC28769169	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477436	OC(=O)c1c(Sc2ccc3OCOc3c2)c2cc3OCOc3cc2n1Cc1ccc2OCOc2c1	InChI=1S/C25H17NO8S/c27-25(28)23-24(35-14-2-4-18-20(6-14)32-11-30-18)15-7-21-22(34-12-33-21)8-16(15)26(23)9-13-1-3-17-19(5-13)31-10-29-17/h1-8H,9-12H2,(H,27,28)	TWBVBLFAEWNYQQ-UHFFFAOYSA-N	50287202	5-Benzo[1,3]dioxol-5-ylmethyl-7-(benzo[1,3]dioxol-5-ylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL283598	Endothelin-1 receptor			 100							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44278215	104128773		CHEMBL283598				ZINC28770468	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477440	CC(C)Oc1c(sc2ccc(OCc3ccccc3)cc12)C(O)=O	InChI=1S/C19H18O4S/c1-12(2)23-17-15-10-14(22-11-13-6-4-3-5-7-13)8-9-16(15)24-18(17)19(20)21/h3-10,12H,11H2,1-2H3,(H,20,21)	MFIHFDWJBWXRFD-UHFFFAOYSA-N	50287187	5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid::CHEMBL10143	Endothelin-1 receptor			 6000							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14673588	104128758		CHEMBL10143				ZINC26004833	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50477443	COc1cccc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc4OCOc4cc23)c1	InChI=1S/C25H19NO7S/c1-29-15-3-2-4-16(8-15)34-24-17-9-21-22(33-13-32-21)10-18(17)26(23(24)25(27)28)11-14-5-6-19-20(7-14)31-12-30-19/h2-10H,11-13H2,1H3,(H,27,28)	XBXUZKKIOMHQDF-UHFFFAOYSA-N	50287182	5-Benzo[1,3]dioxol-5-ylmethyl-7-(3-methoxy-phenylsulfanyl)-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL27617	Endothelin-1 receptor			 84							ChEMBL	10.1016/0960-894X(96)00232-6	10.7270/Q2K35TMT				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287182&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18995999	104128753		CHEMBL27617				ZINC28769459	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482963	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccccc2)c1C	InChI=1S/C16H14N2O5S2/c1-10-11(2)17-23-15(10)18-25(20,21)13-8-9-24-14(13)16(19)22-12-6-4-3-5-7-12/h3-9,18H,1-2H3	LBBSORFJNXBFQV-UHFFFAOYSA-N	50289926	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenyl ester::CHEMBL63611	Endothelin-1 receptor			 4120							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289926&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445345	104131497		CHEMBL63611				ZINC13815548	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482964	Cc1noc(NS(=O)(=O)c2ccsc2C(O)=O)c1Br	InChI=1S/C9H7BrN2O5S2/c1-4-6(10)8(17-11-4)12-19(15,16)5-2-3-18-7(5)9(13)14/h2-3,12H,1H3,(H,13,14)	ITTLWTXFEWOKLP-UHFFFAOYSA-N	50289927	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid::CHEMBL434983	Endothelin-1 receptor			 10210							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289927&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10832763	104131498		CHEMBL434983				ZINC13815552	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482965	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccccc2)c1Br	InChI=1S/C15H11BrN2O5S2/c1-9-12(16)14(23-17-9)18-25(20,21)11-7-8-24-13(11)15(19)22-10-5-3-2-4-6-10/h2-8,18H,1H3	VOXUDBQJZSFURY-UHFFFAOYSA-N	50289928	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenyl ester::CHEMBL304406	Endothelin-1 receptor			 2710							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289928&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445241	104131499		CHEMBL304406				ZINC26176861	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482968	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccccc2)c1Cl	InChI=1S/C15H11ClN2O5S2/c1-9-12(16)14(23-17-9)18-25(20,21)11-7-8-24-13(11)15(19)22-10-5-3-2-4-6-10/h2-8,18H,1H3	SFXQRJNEFZCBGW-UHFFFAOYSA-N	50289931	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenyl ester::CHEMBL291891	Endothelin-1 receptor			 4400							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289931&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445562	104131502		CHEMBL291891				ZINC26184913	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482970	Cc1noc(NS(=O)(=O)c2ccsc2-c2ccccc2)c1Br	InChI=1S/C14H11BrN2O3S2/c1-9-12(15)14(20-16-9)17-22(18,19)11-7-8-21-13(11)10-5-3-2-4-6-10/h2-8,17H,1H3	XBCZCJQNBKILNP-UHFFFAOYSA-N	50288279	2-Phenyl-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL293232	Endothelin-1 receptor			 603							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288279&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998396	104129850		CHEMBL293232				ZINC13815562	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482972	COC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Cl	InChI=1S/C10H9ClN2O5S2/c1-5-7(11)9(18-12-5)13-20(15,16)6-3-4-19-8(6)10(14)17-2/h3-4,13H,1-2H3	CGCWFYMUPJAHOG-UHFFFAOYSA-N	50289934	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid methyl ester::CHEMBL63169	Endothelin-1 receptor			 1090							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289934&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10854399	104131505		CHEMBL63169				ZINC26187857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482973	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2cccc(C)c2)c1Br	InChI=1S/C16H13BrN2O5S2/c1-9-4-3-5-11(8-9)23-16(20)14-12(6-7-25-14)26(21,22)19-15-13(17)10(2)18-24-15/h3-8,19H,1-2H3	PFFISQSGKLUPSY-UHFFFAOYSA-N	50289935	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid m-tolyl ester::CHEMBL291404	Endothelin-1 receptor			 1200							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289935&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445317	104131506		CHEMBL291404				ZINC26185361	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482975	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2)c1Cl	InChI=1S/C15H12ClN3O4S2/c1-9-12(16)15(23-18-9)19-25(21,22)11-7-8-24-13(11)14(20)17-10-5-3-2-4-6-10/h2-8,19H,1H3,(H,17,20)	WTINQQTUVWDWMI-UHFFFAOYSA-N	50289937	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenylamide::CHEMBL65407	Endothelin-1 receptor			 148							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289937&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445325	104131508		CHEMBL65407				ZINC13815566	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482976	COC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C10H9BrN2O5S2/c1-5-7(11)9(18-12-5)13-20(15,16)6-3-4-19-8(6)10(14)17-2/h3-4,13H,1-2H3	GFJCZELBSGPAPC-UHFFFAOYSA-N	50289933	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid methyl ester::CHEMBL65531	Endothelin-1 receptor			 740							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289933&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10833686	104131504		CHEMBL65531				ZINC26182800	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482979	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc3OCOc3c2)c1C	InChI=1S/C17H14N2O7S2/c1-9-10(2)18-26-16(9)19-28(21,22)14-5-6-27-15(14)17(20)25-11-3-4-12-13(7-11)24-8-23-12/h3-7,19H,8H2,1-2H3	LWPRPZFBYSLSLS-UHFFFAOYSA-N	50289936	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester::CHEMBL63290	Endothelin-1 receptor			 6140							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289936&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998414	104131507		CHEMBL63290				ZINC26189086	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482983	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc(C)cc2C)c1Br	InChI=1S/C17H15BrN2O5S2/c1-9-4-5-12(10(2)8-9)24-17(21)15-13(6-7-26-15)27(22,23)20-16-14(18)11(3)19-25-16/h4-8,20H,1-3H3	IURFUNZVDGTHOD-UHFFFAOYSA-N	50289929	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid 2,4-dimethyl-phenyl ester::CHEMBL63937	Endothelin-1 receptor			 290							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289929&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445221	104131500		CHEMBL63937				ZINC26189082	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482984	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc3OCOc3c2)c1Cl	InChI=1S/C16H11ClN2O7S2/c1-8-13(17)15(26-18-8)19-28(21,22)12-4-5-27-14(12)16(20)25-9-2-3-10-11(6-9)24-7-23-10/h2-6,19H,7H2,1H3	JBQRAWXTTIKPRD-UHFFFAOYSA-N	50289940	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester::CHEMBL302872	Endothelin-1 receptor			 8.3							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289940	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289940&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9803428	104131511		CHEMBL302872				ZINC13815640	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482985	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc(C)cc2C)c1C	InChI=1S/C18H18N2O5S2/c1-10-5-6-14(11(2)9-10)24-18(21)16-15(7-8-26-16)27(22,23)20-17-12(3)13(4)19-25-17/h5-9,20H,1-4H3	TWDBQSVPOXBIAE-UHFFFAOYSA-N	50289941	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid 2,4-dimethyl-phenyl ester::CHEMBL65488	Endothelin-1 receptor			 270							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289941&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445224	104131512		CHEMBL65488				ZINC26184929	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482989	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc(C)cc2)c1Br	InChI=1S/C16H13BrN2O5S2/c1-9-3-5-11(6-4-9)23-16(20)14-12(7-8-25-14)26(21,22)19-15-13(17)10(2)18-24-15/h3-8,19H,1-2H3	SFUOJIHGRBIUMD-UHFFFAOYSA-N	50289943	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolyl ester::CHEMBL293877	Endothelin-1 receptor			 9.3							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289943&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445404	104131514		CHEMBL293877				ZINC13815689	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482990	COC(=O)c1sccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C11H12N2O5S2/c1-6-7(2)12-18-10(6)13-20(15,16)8-4-5-19-9(8)11(14)17-3/h4-5,13H,1-3H3	NOXGIYRKHCVIQI-UHFFFAOYSA-N	50289938	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid methyl ester::CHEMBL65639	Endothelin-1 receptor			 3470							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289938&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10615322	104131509		CHEMBL65639				ZINC26175608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482995	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc3OCOc3c2)c1Br	InChI=1S/C16H11BrN2O7S2/c1-8-13(17)15(26-18-8)19-28(21,22)12-4-5-27-14(12)16(20)25-9-2-3-10-11(6-9)24-7-23-10/h2-6,19H,7H2,1H3	JQBUPYPWHBIMNX-UHFFFAOYSA-N	50289945	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester::CHEMBL292802	Endothelin-1 receptor			 8.9							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289945&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9826741	104131516		CHEMBL292802				ZINC13815624	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50482998	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2)c1C	InChI=1S/C16H15N3O4S2/c1-10-11(2)18-23-16(10)19-25(21,22)13-8-9-24-14(13)15(20)17-12-6-4-3-5-7-12/h3-9,19H,1-2H3,(H,17,20)	KUIYVKNCDZSGKO-UHFFFAOYSA-N	50289944	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenylamide::CHEMBL304481	Endothelin-1 receptor			 550							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289944&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445445	104131515		CHEMBL304481				ZINC26178880	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483000	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2)c1Br	InChI=1S/C15H12BrN3O4S2/c1-9-12(16)15(23-18-9)19-25(21,22)11-7-8-24-13(11)14(20)17-10-5-3-2-4-6-10/h2-8,19H,1H3,(H,17,20)	MEXIZICSHQFANT-UHFFFAOYSA-N	50058073	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid phenylamide::CHEMBL45269	Endothelin-1 receptor			 166							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058073&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10503334	103954052		CHEMBL45269				ZINC01540810	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483002	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc(C)cc2)c1C	InChI=1S/C17H16N2O5S2/c1-10-4-6-13(7-5-10)23-17(20)15-14(8-9-25-15)26(21,22)19-16-11(2)12(3)18-24-16/h4-9,19H,1-3H3	SOLWAKQRCKMYQD-UHFFFAOYSA-N	50289939	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolyl ester::CHEMBL63938	Endothelin-1 receptor			 2520							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289939&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998439	104131510		CHEMBL63938				ZINC26187850	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483003	Cc1noc(NS(=O)(=O)c2ccsc2C(O)=O)c1C	InChI=1S/C10H10N2O5S2/c1-5-6(2)11-17-9(5)12-19(15,16)7-3-4-18-8(7)10(13)14/h3-4,12H,1-2H3,(H,13,14)	LAOUJLCAFJDXFP-UHFFFAOYSA-N	50289930	3-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid::CHEMBL64006	Endothelin-1 receptor			 6060							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289930&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10685758	104131501		CHEMBL64006				ZINC13815545	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483004	Cc1noc(NS(=O)(=O)c2ccsc2C(O)=O)c1Cl	InChI=1S/C9H7ClN2O5S2/c1-4-6(10)8(17-11-4)12-19(15,16)5-2-3-18-7(5)9(13)14/h2-3,12H,1H3,(H,13,14)	BFHXYQAPYRDEDW-UHFFFAOYSA-N	50289942	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid::CHEMBL67664	Endothelin-1 receptor			 1060							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289942&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10805820	104131513		CHEMBL67664				ZINC13815570	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483007	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc(C)cc2C)c1Cl	InChI=1S/C17H15ClN2O5S2/c1-9-4-5-12(10(2)8-9)24-17(21)15-13(6-7-26-15)27(22,23)20-16-14(18)11(3)19-25-16/h4-8,20H,1-3H3	LXXHNWBJGQIREA-UHFFFAOYSA-N	50289946	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid 2,4-dimethyl-phenyl ester::CHEMBL303203	Endothelin-1 receptor			 650							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289946&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445412	104131517		CHEMBL303203				ZINC26188690	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483008	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc(C)cc2)c1Cl	InChI=1S/C16H13ClN2O5S2/c1-9-3-5-11(6-4-9)23-16(20)14-12(7-8-25-14)26(21,22)19-15-13(17)10(2)18-24-15/h3-8,19H,1-2H3	JZTVSOZSLJMGFA-UHFFFAOYSA-N	50289932	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid p-tolyl ester::CHEMBL66641	Endothelin-1 receptor			 3220							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289932&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445505	104131503		CHEMBL66641				ZINC26175638	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50483009	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccccc2C)c1Br	InChI=1S/C16H13BrN2O5S2/c1-9-5-3-4-6-11(9)23-16(20)14-12(7-8-25-14)26(21,22)19-15-13(17)10(2)18-24-15/h3-8,19H,1-2H3	UPDYWJFNCPAYLH-UHFFFAOYSA-N	50289947	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid o-tolyl ester::CHEMBL63805	Endothelin-1 receptor			 680							ChEMBL	10.1016/S0960-894X(97)00367-3	10.7270/Q2WH2PZF				Raju, B; Wu, C; Castillo, R; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289947&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998438	104131518		CHEMBL63805				ZINC26183551	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470891	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C77H107N17O21S2/c1-9-40(7)62(75(112)87-55(77(114)115)27-44-30-80-49-19-15-14-18-47(44)49)94-76(113)63(41(8)10-2)93-69(106)54(29-60(99)100)85-65(102)50(24-38(3)4)82-68(105)53(28-45-31-79-37-81-45)84-73(110)59-36-117-116-35-48(78)64(101)88-56(32-95)70(107)89-57(33-96)71(108)90-58(34-97)72(109)92-61(39(5)6)74(111)86-52(26-43-20-22-46(98)23-21-43)66(103)83-51(67(104)91-59)25-42-16-12-11-13-17-42/h11-23,30-31,37-41,48,50-59,61-63,80,95-98H,9-10,24-29,32-36,78H2,1-8H3,(H,79,81)(H,82,105)(H,83,103)(H,84,110)(H,85,102)(H,86,111)(H,87,112)(H,88,101)(H,89,107)(H,90,108)(H,91,104)(H,92,109)(H,93,106)(H,94,113)(H,99,100)(H,114,115)/t40-,41-,48-,50-,51-,52+,53-,54-,55-,56-,57-,58-,59+,61-,62-,63-/m0/s1	VEIVGAZRXCMCGI-QLTPMWFJSA-N	50284007	CHEMBL412460::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Ser-Ser-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 2500							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			77282141	104125664		CHEMBL412460					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470892	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)NCCCCC(=O)N[C@H](C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C76H106N16O18S2/c1-9-42(7)63(74(107)87-57(76(109)110)31-46-34-80-51-21-15-14-20-49(46)51)92-75(108)64(43(8)10-2)91-71(104)56(33-61(96)97)85-67(100)52(28-40(3)4)82-70(103)55(32-47-35-78-39-81-47)84-72(105)59-38-112-111-37-50(77)65(98)88-58(36-93)66(99)79-27-17-16-22-60(95)90-62(41(5)6)73(106)86-54(30-45-23-25-48(94)26-24-45)68(101)83-53(69(102)89-59)29-44-18-12-11-13-19-44/h11-15,18-21,23-26,34-35,39-43,50,52-59,62-64,80,93-94H,9-10,16-17,22,27-33,36-38,77H2,1-8H3,(H,78,81)(H,79,99)(H,82,103)(H,83,101)(H,84,105)(H,85,100)(H,86,106)(H,87,107)(H,88,98)(H,89,102)(H,90,95)(H,91,104)(H,92,108)(H,96,97)(H,109,110)/t42-,43-,50-,52-,53+,54-,55-,56-,57-,58-,59+,62+,63-,64-/m0/s1	DOBUMMJIGJNUMP-ANRTWLEFSA-N	50284008	CHEMBL265164::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Apa-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 2500							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284008&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			77282142	104125665		CHEMBL265164					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470898	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C86H121N19O24S2/c1-9-45(7)70(84(126)100-63(86(128)129)33-49-37-90-54-21-15-14-20-52(49)54)105-85(127)71(46(8)10-2)104-80(122)62(36-68(112)113)97-75(117)57(30-43(3)4)94-78(120)60(34-50-38-89-42-91-50)96-82(124)65-41-131-130-40-53(88)72(114)101-64(39-106)81(123)98-61(35-67(110)111)79(121)92-55(22-16-17-29-87)73(115)93-56(27-28-66(108)109)74(116)103-69(44(5)6)83(125)99-59(32-48-23-25-51(107)26-24-48)76(118)95-58(77(119)102-65)31-47-18-12-11-13-19-47/h11-15,18-21,23-26,37-38,42-46,53,55-65,69-71,90,106-107H,9-10,16-17,22,27-36,39-41,87-88H2,1-8H3,(H,89,91)(H,92,121)(H,93,115)(H,94,120)(H,95,118)(H,96,124)(H,97,117)(H,98,123)(H,99,125)(H,100,126)(H,101,114)(H,102,119)(H,103,116)(H,104,122)(H,105,127)(H,108,109)(H,110,111)(H,112,113)(H,128,129)/t45-,46-,53-,55-,56+,57-,58-,59+,60-,61+,62-,63-,64-,65+,69-,70-,71-/m0/s1	IDHJMMZCVSLAEB-UANWIAGESA-N	50284011	CHEMBL438768::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Asp-Lys-Glu-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 7100							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284011&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			77282144	104125668		CHEMBL438768					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470901	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C74H102N16O19S2/c1-9-39(7)60(72(106)84-54(74(108)109)27-43-30-77-48-19-15-14-18-46(43)48)90-73(107)61(40(8)10-2)89-67(101)53(29-58(94)95)82-63(97)49(24-37(3)4)79-66(100)52(28-44-31-76-36-78-44)81-70(104)57-35-111-110-34-47(75)62(96)85-55(32-91)68(102)86-56(33-92)69(103)88-59(38(5)6)71(105)83-51(26-42-20-22-45(93)23-21-42)64(98)80-50(65(99)87-57)25-41-16-12-11-13-17-41/h11-23,30-31,36-40,47,49-57,59-61,77,91-93H,9-10,24-29,32-35,75H2,1-8H3,(H,76,78)(H,79,100)(H,80,98)(H,81,104)(H,82,97)(H,83,105)(H,84,106)(H,85,96)(H,86,102)(H,87,99)(H,88,103)(H,89,101)(H,90,107)(H,94,95)(H,108,109)/t39-,40-,47-,49-,50-,51+,52-,53-,54-,55-,56-,57+,59-,60-,61-/m0/s1	IFHNRTZWBQMTBA-GUZQDNCUSA-N	50284010	CHEMBL436899::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Ser-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 2000							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284010&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			77282143	104125667		CHEMBL436899					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470904	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C77H119N19O24S3/c1-10-39(7)61(75(117)91-54(77(119)120)26-41-30-81-45-17-13-12-16-43(41)45)96-76(118)62(40(8)11-2)95-71(113)53(29-60(103)104)90-68(110)50(25-38(5)6)86-69(111)51(27-42-31-80-36-82-42)88-74(116)57-35-123-122-34-44(79)63(105)92-55(32-97)73(115)93-56(33-98)72(114)87-49(24-37(3)4)67(109)85-48(21-23-121-9)66(108)89-52(28-59(101)102)70(112)83-46(18-14-15-22-78)64(106)84-47(65(107)94-57)19-20-58(99)100/h12-13,16-17,30-31,36-40,44,46-57,61-62,81,97-98H,10-11,14-15,18-29,32-35,78-79H2,1-9H3,(H,80,82)(H,83,112)(H,84,106)(H,85,109)(H,86,111)(H,87,114)(H,88,116)(H,89,108)(H,90,110)(H,91,117)(H,92,105)(H,93,115)(H,94,107)(H,95,113)(H,96,118)(H,99,100)(H,101,102)(H,103,104)(H,119,120)/t39-,40-,44-,46+,47-,48+,49-,50-,51-,52-,53-,54-,55-,56+,57+,61-,62-/m0/s1	MZYDFYKGCPLSCB-AGRNAASLSA-N	50284013	CHEMBL409777::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys)	Endothelin-1 receptor			>10000							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284013&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44368812	104125670		CHEMBL409777					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470911	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C71H97N15O17S2/c1-9-38(7)58(69(100)81-53(71(102)103)27-42-30-74-47-19-15-14-18-45(42)47)86-70(101)59(39(8)10-2)85-65(96)52(29-56(89)90)79-61(92)48(24-36(3)4)76-64(95)51(28-43-31-73-35-75-43)78-67(98)55-34-105-104-33-46(72)60(91)82-54(32-87)66(97)84-57(37(5)6)68(99)80-50(26-41-20-22-44(88)23-21-41)62(93)77-49(63(94)83-55)25-40-16-12-11-13-17-40/h11-23,30-31,35-39,46,48-55,57-59,74,87-88H,9-10,24-29,32-34,72H2,1-8H3,(H,73,75)(H,76,95)(H,77,93)(H,78,98)(H,79,92)(H,80,99)(H,81,100)(H,82,91)(H,83,94)(H,84,97)(H,85,96)(H,86,101)(H,89,90)(H,102,103)/t38-,39-,46-,48-,49-,50+,51-,52-,53-,54-,55+,57-,58-,59-/m0/s1	NFALCSTYLUFIHX-TWAFHRHTSA-N	50284009	CHEMBL408141::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 3800							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284009&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44368903	104125666		CHEMBL408141					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470912	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C68H92N14O15S2/c1-9-37(7)56(66(94)78-52(68(96)97)27-41-30-71-46-19-15-14-18-44(41)46)82-67(95)57(38(8)10-2)81-63(91)51(29-54(84)85)76-59(87)47(24-35(3)4)73-62(90)50(28-42-31-70-34-72-42)75-64(92)53-33-99-98-32-45(69)58(86)80-55(36(5)6)65(93)77-49(26-40-20-22-43(83)23-21-40)60(88)74-48(61(89)79-53)25-39-16-12-11-13-17-39/h11-23,30-31,34-38,45,47-53,55-57,71,83H,9-10,24-29,32-33,69H2,1-8H3,(H,70,72)(H,73,90)(H,74,88)(H,75,92)(H,76,87)(H,77,93)(H,78,94)(H,79,89)(H,80,86)(H,81,91)(H,82,95)(H,84,85)(H,96,97)/t37-,38-,45-,47-,48-,49+,50-,51-,52-,53+,55-,56-,57-/m0/s1	OETKRDJJNWJFOP-OUBBGVQJSA-N	50284014	CHEMBL436884::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 2600							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284014&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44368904	104125671		CHEMBL436884					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50470914	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)NCCCCCCCC(=O)N[C@H](C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C79H112N16O18S2/c1-9-45(7)66(77(110)90-60(79(112)113)34-49-37-83-54-24-19-18-23-52(49)54)95-78(111)67(46(8)10-2)94-74(107)59(36-64(99)100)88-70(103)55(31-43(3)4)85-73(106)58(35-50-38-81-42-84-50)87-75(108)62-41-115-114-40-53(80)68(101)91-61(39-96)69(102)82-30-20-13-11-12-17-25-63(98)93-65(44(5)6)76(109)89-57(33-48-26-28-51(97)29-27-48)71(104)86-56(72(105)92-62)32-47-21-15-14-16-22-47/h14-16,18-19,21-24,26-29,37-38,42-46,53,55-62,65-67,83,96-97H,9-13,17,20,25,30-36,39-41,80H2,1-8H3,(H,81,84)(H,82,102)(H,85,106)(H,86,104)(H,87,108)(H,88,103)(H,89,109)(H,90,110)(H,91,101)(H,92,105)(H,93,98)(H,94,107)(H,95,111)(H,99,100)(H,112,113)/t45-,46-,53-,55-,56+,57-,58-,59-,60-,61-,62+,65+,66-,67-/m0/s1	NHZQUBBECJWSBV-CFXZIQGZSA-N	50284006	CHEMBL438380::Trp-Ile-Ile-Asp-Leu-Hisc(Cys-Ser-Aoa-Val-Tyr-Phe-Cys)	Endothelin-1 receptor			 1800							ChEMBL	10.1016/S0960-894X(01)80156-6	10.7270/Q2TT4QW6				Cody, WL; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GP; Dudley, DT; Hill, KE; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284006&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			77282140	104125663		CHEMBL438380					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472181	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccc(Cl)cc1Cl)C(O)=O	InChI=1S/C25H16Cl2O5/c26-12-6-8-13(18(27)10-12)11-5-7-15-17(9-11)23(28)16-4-2-1-3-14(16)19-20(15)22(25(31)32)21(19)24(29)30/h1-10,19-22H,(H,29,30)(H,31,32)/t19-,20+,21-,22+/m0/s1	KMMZABBBQDVUIN-LNRXMEIDSA-N	50284703	5-(2,4-dichlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL29265	Endothelin-1 receptor			 7600							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284703&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279126	104126274		CHEMBL29265				ZINC29204287	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472182	COc1ccc(cc1)-c1ccc2[C@H]3[C@H]([C@H]([C@H]3c3ccccc3C(=O)c2c1)C(O)=O)C(O)=O	InChI=1S/C26H20O6/c1-32-15-9-6-13(7-10-15)14-8-11-17-19(12-14)24(27)18-5-3-2-4-16(18)20-21(17)23(26(30)31)22(20)25(28)29/h2-12,20-23H,1H3,(H,28,29)(H,30,31)/t20-,21+,22-,23+/m0/s1	NWZLYDCUPZYBAX-GSPCLOLRSA-N	50284704	5-(4-methoxyphenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL31469	Endothelin-1 receptor			 530							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284704&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279128	104126275		CHEMBL31469				ZINC29204638	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472183	COc1cccc(c1)-c1ccc2[C@H]3[C@H]([C@H]([C@H]3c3ccccc3C(=O)c2c1)C(O)=O)C(O)=O	InChI=1S/C26H20O6/c1-32-15-6-4-5-13(11-15)14-9-10-17-19(12-14)24(27)18-8-3-2-7-16(18)20-21(17)23(26(30)31)22(20)25(28)29/h2-12,20-23H,1H3,(H,28,29)(H,30,31)/t20-,21+,22-,23+/m0/s1	KLCWPVZQNLUMTN-GSPCLOLRSA-N	50284705	5-(3-methoxyphenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL433229	Endothelin-1 receptor			 3900							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284705&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279350	104126276		CHEMBL433229				ZINC29206874	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472187	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccccc1)C(O)=O	InChI=1S/C25H18O5/c26-23-17-9-5-4-8-15(17)19-20(22(25(29)30)21(19)24(27)28)16-11-10-14(12-18(16)23)13-6-2-1-3-7-13/h1-12,19-22H,(H,27,28)(H,29,30)/t19-,20+,21-,22+/m0/s1	IJKPAPFBDVRAPA-LNRXMEIDSA-N	50284709	7-oxo-5-phenyl-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286687	Endothelin-1 receptor			 290							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284709&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279383	104126280		CHEMBL286687				ZINC29206404	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472188	CCc1ccc(cc1)-c1ccc2[C@H]3[C@H]([C@H]([C@H]3c3ccccc3C(=O)c2c1)C(O)=O)C(O)=O	InChI=1S/C27H22O5/c1-2-14-7-9-15(10-8-14)16-11-12-18-20(13-16)25(28)19-6-4-3-5-17(19)21-22(18)24(27(31)32)23(21)26(29)30/h3-13,21-24H,2H2,1H3,(H,29,30)(H,31,32)/t21-,22+,23-,24+/m0/s1	AAQHGXPJHYKNDF-UARRHKHWSA-N	50284706	5-(4-ethylphenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL31662	Endothelin-1 receptor			 350							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284706&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279370	104126277		CHEMBL31662				ZINC29207490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472189	Cc1ccccc1-c1ccc2[C@H]3[C@H]([C@H]([C@H]3c3ccccc3C(=O)c2c1)C(O)=O)C(O)=O	InChI=1S/C26H20O5/c1-13-6-2-3-7-15(13)14-10-11-17-19(12-14)24(27)18-9-5-4-8-16(18)20-21(17)23(26(30)31)22(20)25(28)29/h2-12,20-23H,1H3,(H,28,29)(H,30,31)/t20-,21+,22-,23+/m0/s1	FPPSDLIYYVXVBW-GSPCLOLRSA-N	50284710	5-(2-methylphenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286333	Endothelin-1 receptor			 5000							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284710&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279351	104126281		CHEMBL286333				ZINC29206943	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472191	Cc1ccc(cc1)-c1ccc2[C@H]3[C@H]([C@H]([C@H]3c3ccccc3C(=O)c2c1)C(O)=O)C(O)=O	InChI=1S/C26H20O5/c1-13-6-8-14(9-7-13)15-10-11-17-19(12-15)24(27)18-5-3-2-4-16(18)20-21(17)23(26(30)31)22(20)25(28)29/h2-12,20-23H,1H3,(H,28,29)(H,30,31)/t20-,21+,22-,23+/m0/s1	ZGXRPHUWXAFFDA-GSPCLOLRSA-N	50284711	5-(4-methylphenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL414408	Endothelin-1 receptor			 150							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284711&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279309	104126282		CHEMBL414408				ZINC29207436	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472192	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1cc(Cl)cc(Cl)c1)C(O)=O	InChI=1S/C25H16Cl2O5/c26-13-7-12(8-14(27)10-13)11-5-6-16-18(9-11)23(28)17-4-2-1-3-15(17)19-20(16)22(25(31)32)21(19)24(29)30/h1-10,19-22H,(H,29,30)(H,31,32)/t19-,20+,21-,22+/m0/s1	UUAWHNKOGOBWQF-LNRXMEIDSA-N	50284712	5-(3,5-dichlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286214	Endothelin-1 receptor			 26000							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284712&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279371	104126283		CHEMBL286214				ZINC29207493	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472196	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccc(Cl)cc1)C(O)=O	InChI=1S/C25H17ClO5/c26-14-8-5-12(6-9-14)13-7-10-16-18(11-13)23(27)17-4-2-1-3-15(17)19-20(16)22(25(30)31)21(19)24(28)29/h1-11,19-22H,(H,28,29)(H,30,31)/t19-,20+,21-,22+/m0/s1	RBIUYHJGRUEIPU-LNRXMEIDSA-N	50284708	5-(4-chlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL283200	Endothelin-1 receptor			 47							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284708&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279127	104126279		CHEMBL283200				ZINC29204292	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472197	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1ccc(cc1C(F)(F)F)C(F)(F)F)C(O)=O	InChI=1S/C27H16F6O5/c28-26(29,30)12-6-8-13(18(10-12)27(31,32)33)11-5-7-15-17(9-11)23(34)16-4-2-1-3-14(16)19-20(15)22(25(37)38)21(19)24(35)36/h1-10,19-22H,(H,35,36)(H,37,38)/t19-,20+,21-,22+/m0/s1	KCRIBTBBBIPKHG-LNRXMEIDSA-N	50284715	5-[2,4-di(trifluoromethyl)phenyl]-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL31781	Endothelin-1 receptor			 25000							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284715&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279439	104126286		CHEMBL31781				ZINC29208911	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472198	OC(=O)[C@H]1[C@H]([C@@H]2[C@H]1c1ccc(Br)cc1C(=O)c1cc(Br)ccc21)C(O)=O	InChI=1S/C19H12Br2O5/c20-7-1-3-9-11(5-7)17(22)12-6-8(21)2-4-10(12)14-13(9)15(18(23)24)16(14)19(25)26/h1-6,13-16H,(H,23,24)(H,25,26)/t13-,14+,15-,16+	UIRWQOJPYZYVQA-GEEKYZPCSA-N	50284713	5,9-dibromo-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL30297	Endothelin-1 receptor			 650							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284713&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279677	104126284		CHEMBL30297				ZINC29211478	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472202	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(Br)ccc21)C(O)=O	InChI=1S/C19H13BrO5/c20-8-5-6-10-12(7-8)17(21)11-4-2-1-3-9(11)13-14(10)16(19(24)25)15(13)18(22)23/h1-7,13-16H,(H,22,23)(H,24,25)/t13-,14+,15-,16+/m0/s1	PTGZJENBFJFKND-XUWVNRHRSA-N	50284716	5-bromo-7-oxo-(1S,2R)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286395	Endothelin-1 receptor			 400							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284716&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279413	104126287		CHEMBL286395				ZINC29206795	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472205	OC(=O)[C@H]1[C@H]([C@@H]2[C@H]1c1ccccc1C(=O)c1ccccc21)C(O)=O	InChI=1S/C19H14O5/c20-17-11-7-3-1-5-9(11)13-14(10-6-2-4-8-12(10)17)16(19(23)24)15(13)18(21)22/h1-8,13-16H,(H,21,22)(H,23,24)/t13-,14+,15-,16+	BDGPBYUEDIIAAK-GEEKYZPCSA-N	50284717	7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286808	Endothelin-1 receptor			 800							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284717&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14041110	104126288		CHEMBL286808				ZINC29208846	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472206	OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1cccc2ccccc12)C(O)=O	InChI=1S/C29H20O5/c30-27-21-10-4-3-9-19(21)23-24(26(29(33)34)25(23)28(31)32)20-13-12-16(14-22(20)27)18-11-5-7-15-6-1-2-8-17(15)18/h1-14,23-26H,(H,31,32)(H,33,34)/t23-,24+,25-,26+/m0/s1	IINURLQUSCGKMH-ROXDYWFKSA-N	50284707	5-(1-naphthyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL433039	Endothelin-1 receptor			 15000							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284707&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279349	104126278		CHEMBL433039				ZINC04634254	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50472209	COc1ccccc1-c1ccc2[C@H]3[C@H]([C@H]([C@H]3c3ccccc3C(=O)c2c1)C(O)=O)C(O)=O	InChI=1S/C26H20O6/c1-32-19-9-5-4-6-14(19)13-10-11-16-18(12-13)24(27)17-8-3-2-7-15(17)20-21(16)23(26(30)31)22(20)25(28)29/h2-12,20-23H,1H3,(H,28,29)(H,30,31)/t20-,21+,22-,23+/m0/s1	OMXFCSAUSDBHBL-GSPCLOLRSA-N	50284714	5-(2-methoxyphenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL31524	Endothelin-1 receptor			 48000							ChEMBL	10.1016/0960-894X(95)00230-Q	10.7270/Q2BK1C9J				Rivero, RA; Greenlee, WJ; Williams, PD; Kieczykowski, GR; Williams, DL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284714&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279129	104126285		CHEMBL31524				ZINC29205851	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476608	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCCC(O)=O	InChI=1S/C29H43N5O5/c1-20(2)17-23(32-29(39)34-15-8-4-5-9-16-34)28(38)31-24(27(37)30-14-10-13-26(35)36)18-21-19-33(3)25-12-7-6-11-22(21)25/h6-7,11-12,19-20,23-24H,4-5,8-10,13-18H2,1-3H3,(H,30,37)(H,31,38)(H,32,39)(H,35,36)/t23-,24+/m0/s1	CSFPMIPVKVIPJG-BJKOFHAPSA-N	50286791	4-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-butyric acid::CHEMBL422720	Endothelin-1 receptor			 140							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286791&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44382933	104128362		CHEMBL422720				ZINC28000907	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476609	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(O)=O	InChI=1S/C34H45N5O5/c1-23(2)19-27(37-34(44)39-17-11-4-5-12-18-39)31(40)35-28(21-25-22-38(3)30-16-10-9-15-26(25)30)32(41)36-29(33(42)43)20-24-13-7-6-8-14-24/h6-10,13-16,22-23,27-29H,4-5,11-12,17-21H2,1-3H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t27-,28+,29+/m0/s1	PITCHIBGLRHGTD-ZGIBFIJWSA-N	50286792	(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-3-phenyl-propionic acid::CHEMBL171198	Endothelin-1 receptor			 2.5							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286792	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286792&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10100163	104128363		CHEMBL171198				ZINC27999250	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476610	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](CC(O)=O)C(O)=O	InChI=1S/C29H41N5O7/c1-18(2)14-21(32-29(41)34-12-8-4-5-9-13-34)26(37)30-22(27(38)31-23(28(39)40)16-25(35)36)15-19-17-33(3)24-11-7-6-10-20(19)24/h6-7,10-11,17-18,21-23H,4-5,8-9,12-16H2,1-3H3,(H,30,37)(H,31,38)(H,32,41)(H,35,36)(H,39,40)/t21-,22+,23+/m0/s1	OBDFCBOIWCPVCN-YTFSRNRJSA-N	50286793	(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-succinic acid::CHEMBL170600	Endothelin-1 receptor			 295							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286793	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286793&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383189	104128364		CHEMBL170600			C06380	ZINC28000676	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476611	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCc1nc(cs1)C(O)=O	InChI=1S/C30H40N6O5S/c1-19(2)14-22(34-30(41)36-12-8-4-5-9-13-36)28(38)33-23(15-20-17-35(3)25-11-7-6-10-21(20)25)27(37)31-16-26-32-24(18-42-26)29(39)40/h6-7,10-11,17-19,22-23H,4-5,8-9,12-16H2,1-3H3,(H,31,37)(H,33,38)(H,34,41)(H,39,40)/t22-,23+/m0/s1	MPZZEJMYDNCQMW-XZOQPEGZSA-N	50286794	2-{[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-methyl}-thiazole-4-carboxylic acid::CHEMBL352929	Endothelin-1 receptor			 1100							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286794&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44382975	104128365		CHEMBL352929				ZINC28006722	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476612	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(O)=O	InChI=1S/C37H48N6O5/c1-24(2)19-29(40-37(48)43-17-11-5-6-12-18-43)34(44)38-30(20-25-22-41(3)32-15-9-7-13-27(25)32)35(45)39-31(36(46)47)21-26-23-42(4)33-16-10-8-14-28(26)33/h7-10,13-16,22-24,29-31H,5-6,11-12,17-21H2,1-4H3,(H,38,44)(H,39,45)(H,40,48)(H,46,47)/t29-,30+,31+/m0/s1	HLFOKHOTHSEMFU-OJDZSJEKSA-N	50286795	(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-3-(1-methyl-1H-indol-3-yl)-propionic acid::CHEMBL354152	Endothelin-1 receptor			 8							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286795&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383602	104128366		CHEMBL354152				ZINC28007653	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476613	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCCCC(O)=O	InChI=1S/C30H45N5O5/c1-21(2)18-24(33-30(40)35-16-10-4-5-11-17-35)29(39)32-25(28(38)31-15-9-8-14-27(36)37)19-22-20-34(3)26-13-7-6-12-23(22)26/h6-7,12-13,20-21,24-25H,4-5,8-11,14-19H2,1-3H3,(H,31,38)(H,32,39)(H,33,40)(H,36,37)/t24-,25+/m0/s1	FHLMWTMLXWIZIG-LOSJGSFVSA-N	50286796	5-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-pentanoic acid::CHEMBL369667	Endothelin-1 receptor			>3500							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286796&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383573	104128367		CHEMBL369667				ZINC28012639	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476614	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](CC(N)=O)C(O)=O	InChI=1S/C29H42N6O6/c1-18(2)14-21(33-29(41)35-12-8-4-5-9-13-35)26(37)31-22(27(38)32-23(28(39)40)16-25(30)36)15-19-17-34(3)24-11-7-6-10-20(19)24/h6-7,10-11,17-18,21-23H,4-5,8-9,12-16H2,1-3H3,(H2,30,36)(H,31,37)(H,32,38)(H,33,41)(H,39,40)/t21-,22+,23+/m0/s1	SDLUFIKRIAFAED-YTFSRNRJSA-N	50286797	(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-succinamic acid::CHEMBL355384	Endothelin-1 receptor			>3500							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286797&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383188	104128368		CHEMBL355384				ZINC28000088	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476615	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NC(C)(C)C(O)=O	InChI=1S/C29H43N5O5/c1-19(2)16-22(31-28(39)34-14-10-6-7-11-15-34)25(35)30-23(26(36)32-29(3,4)27(37)38)17-20-18-33(5)24-13-9-8-12-21(20)24/h8-9,12-13,18-19,22-23H,6-7,10-11,14-17H2,1-5H3,(H,30,35)(H,31,39)(H,32,36)(H,37,38)/t22-,23+/m0/s1	PNIOOYSMYALOCP-XZOQPEGZSA-N	50286798	2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-2-methyl-propionic acid::CHEMBL353605	Endothelin-1 receptor			 730							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286798&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383330	104128369		CHEMBL353605				ZINC28004145	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476616	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCCCCC(O)=O	InChI=1S/C31H47N5O5/c1-22(2)19-25(34-31(41)36-17-11-4-5-12-18-36)30(40)33-26(29(39)32-16-10-6-7-15-28(37)38)20-23-21-35(3)27-14-9-8-13-24(23)27/h8-9,13-14,21-22,25-26H,4-7,10-12,15-20H2,1-3H3,(H,32,39)(H,33,40)(H,34,41)(H,37,38)/t25-,26+/m0/s1	MLKHRNAWGXGMII-IZZNHLLZSA-N	50286799	6-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-hexanoic acid::CHEMBL174230	Endothelin-1 receptor			>3500							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286799&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383572	104128370		CHEMBL174230				ZINC28007790	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476617	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](CO)C(O)=O	InChI=1S/C28H41N5O6/c1-18(2)14-21(31-28(39)33-12-8-4-5-9-13-33)25(35)29-22(26(36)30-23(17-34)27(37)38)15-19-16-32(3)24-11-7-6-10-20(19)24/h6-7,10-11,16,18,21-23,34H,4-5,8-9,12-15,17H2,1-3H3,(H,29,35)(H,30,36)(H,31,39)(H,37,38)/t21-,22+,23+/m0/s1	GHWMOQMDESTBOY-YTFSRNRJSA-N	50286800	(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-3-hydroxy-propionic acid::CHEMBL354082	Endothelin-1 receptor			 8							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286800&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10392605	104128371		CHEMBL354082				ZINC28001453	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476618	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCc1cccc(CCC(O)=O)c1	InChI=1S/C35H47N5O5/c1-24(2)19-29(38-35(45)40-17-8-4-5-9-18-40)34(44)37-30(21-27-23-39(3)31-14-7-6-13-28(27)31)33(43)36-22-26-12-10-11-25(20-26)15-16-32(41)42/h6-7,10-14,20,23-24,29-30H,4-5,8-9,15-19,21-22H2,1-3H3,(H,36,43)(H,37,44)(H,38,45)(H,41,42)/t29-,30+/m0/s1	XXIWLNFCSMAXEK-XZWHSSHBSA-N	50286801	3-(3-{[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-methyl}-phenyl)-propionic acid::CHEMBL173974	Endothelin-1 receptor			 420							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286801&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383187	104128372		CHEMBL173974				ZINC28008284	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476619	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCCC(O)=O	InChI=1S/C28H41N5O5/c1-19(2)16-22(31-28(38)33-14-8-4-5-9-15-33)27(37)30-23(26(36)29-13-12-25(34)35)17-20-18-32(3)24-11-7-6-10-21(20)24/h6-7,10-11,18-19,22-23H,4-5,8-9,12-17H2,1-3H3,(H,29,36)(H,30,37)(H,31,38)(H,34,35)/t22-,23+/m0/s1	UUTDVHMSEUUXBC-XZOQPEGZSA-N	50286802	3-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-propionic acid::CHEMBL173808	Endothelin-1 receptor			 62							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286802&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9984393	104128373		CHEMBL173808				ZINC28009352	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476620	CC(C)C[C@H](NC(=O)[C@@H](Cc1cn(C)c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1)C(O)=O	InChI=1S/C31H47N5O5/c1-20(2)16-24(34-31(41)36-14-10-6-7-11-15-36)28(37)32-25(29(38)33-26(30(39)40)17-21(3)4)18-22-19-35(5)27-13-9-8-12-23(22)27/h8-9,12-13,19-21,24-26H,6-7,10-11,14-18H2,1-5H3,(H,32,37)(H,33,38)(H,34,41)(H,39,40)/t24-,25+,26-/m0/s1	SHAXLXFOLCXADY-NXCFDTQHSA-N	50286803	(S)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-4-methyl-pentanoic acid::CHEMBL170229	Endothelin-1 receptor			 1320							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286803&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44382976	104128374		CHEMBL170229				ZINC28006726	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476621	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)N[C@H](Cc1ccccn1)C(O)=O	InChI=1S/C33H44N6O5/c1-22(2)18-26(37-33(44)39-16-10-4-5-11-17-39)30(40)35-27(19-23-21-38(3)29-14-7-6-13-25(23)29)31(41)36-28(32(42)43)20-24-12-8-9-15-34-24/h6-9,12-15,21-22,26-28H,4-5,10-11,16-20H2,1-3H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43)/t26-,27+,28+/m0/s1	LIOKMIQQPDDTNO-UPRLRBBYSA-N	50286804	(R)-2-[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-3-pyridin-2-yl-propionic acid::CHEMBL352396	Endothelin-1 receptor			 5.3							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286804&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			107810	104128375		CHEMBL352396		998		ZINC03922715	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476622	CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCC(O)=O	InChI=1S/C27H39N5O5/c1-18(2)14-21(30-27(37)32-12-8-4-5-9-13-32)26(36)29-22(25(35)28-16-24(33)34)15-19-17-31(3)23-11-7-6-10-20(19)23/h6-7,10-11,17-18,21-22H,4-5,8-9,12-16H2,1-3H3,(H,28,35)(H,29,36)(H,30,37)(H,33,34)/t21-,22+/m0/s1	QBMRMNYMZHQMFI-FCHUYYIVSA-N	50286805	CHEMBL170121::[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-acetic acid	Endothelin-1 receptor			 220							ChEMBL	10.1016/0960-894X(95)00144-I	10.7270/Q28S4PWG				Terrett, NK; Bojanic, D; Brown, D; Bungay, PJ; Gardner, M; Gordon, DW; Mayers, CJ; Steele, J	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286805&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383241	104128376		CHEMBL170121				ZINC28003836	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480046	COC(=O)C(C1c2ccccc2CCc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C25H22O4/c1-27-25(26)23(18-12-13-21-22(14-18)29-15-28-21)24-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)24/h2-9,12-14,23-24H,10-11,15H2,1H3	YRFGKNFBHATPQQ-UHFFFAOYSA-N	50288531	Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-acetic acid methyl ester::CHEMBL103362	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288531&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332777	104130102		CHEMBL103362				ZINC26815859	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480050	COC(=O)C(c1ccc(Cl)c(Cl)c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H15Cl2NO2/c1-27-22(26)20(13-10-11-16(23)17(24)12-13)21-14-6-2-4-8-18(14)25-19-9-5-3-7-15(19)21/h2-12,20H,1H3	UEBHINCCWHIGGV-UHFFFAOYSA-N	50288535	Acridin-9-yl-(3,4-dichloro-phenyl)-acetic acid methyl ester::CHEMBL103872	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288535&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332345	104130106		CHEMBL103872				ZINC26819611	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480054	COC(=O)C(Oc1c2ccccc2nc2ccccc12)c1ccc2OCOc2c1	InChI=1S/C23H17NO5/c1-26-23(25)21(14-10-11-19-20(12-14)28-13-27-19)29-22-15-6-2-4-8-17(15)24-18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	XVWPMUDIMPSZCK-UHFFFAOYSA-N	50288538	(Acridin-9-yloxy)-benzo[1,3]dioxol-5-yl-acetic acid methyl ester::CHEMBL330414	Endothelin-1 receptor			 2200							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288538&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10385531	104130109		CHEMBL330414				ZINC26753060	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480062	COC(=O)C(c1ccc2OCOc2c1)c1cc(C)nc2ccccc12	InChI=1S/C20H17NO4/c1-12-9-15(14-5-3-4-6-16(14)21-12)19(20(22)23-2)13-7-8-17-18(10-13)25-11-24-17/h3-10,19H,11H2,1-2H3	GTTDDHFXENWZAW-UHFFFAOYSA-N	50288545	Benzo[1,3]dioxol-5-yl-(2-methyl-quinolin-4-yl)-acetic acid methyl ester::CHEMBL103497	Endothelin-1 receptor			 2800							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288545&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332803	104130116		CHEMBL103497				ZINC26818238	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480073	COC(=O)C(c1ccc(OC)c(OC)c1)c1c2ccccc2nc2ccccc12	InChI=1S/C24H21NO4/c1-27-20-13-12-15(14-21(20)28-2)22(24(26)29-3)23-16-8-4-6-10-18(16)25-19-11-7-5-9-17(19)23/h4-14,22H,1-3H3	WBBHMOSIDJLELA-UHFFFAOYSA-N	50288551	Acridin-9-yl-(3,4-dimethoxy-phenyl)-acetic acid methyl ester::CHEMBL103308	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288551&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21559928	104130122		CHEMBL103308				ZINC26820006	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480077	COC(=O)C(c1ccc2OCOc2c1)c1cc(nc2ccccc12)-c1ccccc1	InChI=1S/C25H19NO4/c1-28-25(27)24(17-11-12-22-23(13-17)30-15-29-22)19-14-21(16-7-3-2-4-8-16)26-20-10-6-5-9-18(19)20/h2-14,24H,15H2,1H3	JHTFPOOWJFSFAY-UHFFFAOYSA-N	50288553	Benzo[1,3]dioxol-5-yl-(2-phenyl-quinolin-4-yl)-acetic acid methyl ester::CHEMBL103631	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288553&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332775	104130124		CHEMBL103631				ZINC26819636	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480078	CC(C)(C)OC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C26H23NO4/c1-26(2,3)31-25(28)23(16-12-13-21-22(14-16)30-15-29-21)24-17-8-4-6-10-19(17)27-20-11-7-5-9-18(20)24/h4-14,23H,15H2,1-3H3	KTLCBCNCYPCXHN-UHFFFAOYSA-N	50288532	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid tert-butyl ester::CHEMBL100874	Endothelin-1 receptor			 5600							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288532&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332578	104130103		CHEMBL100874				ZINC26753040	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480079	COC(=O)C(c1ccc(cc1)[N+]([O-])=O)c1c2ccccc2nc2ccccc12	InChI=1S/C22H16N2O4/c1-28-22(25)20(14-10-12-15(13-11-14)24(26)27)21-16-6-2-4-8-18(16)23-19-9-5-3-7-17(19)21/h2-13,20H,1H3	WCIYXANHYASICQ-UHFFFAOYSA-N	50288554	Acridin-9-yl-(4-nitro-phenyl)-acetic acid methyl ester::CHEMBL103573	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288554&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332824	104130125		CHEMBL103573				ZINC26818916	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480080	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2nc2c(OC)c(OC)ccc12	InChI=1S/C25H21NO6/c1-28-19-11-9-16-22(15-6-4-5-7-17(15)26-23(16)24(19)29-2)21(25(27)30-3)14-8-10-18-20(12-14)32-13-31-18/h4-12,21H,13H2,1-3H3	WJKGYOIXXYWTDD-UHFFFAOYSA-N	50288549	Benzo[1,3]dioxol-5-yl-(3,4-dimethoxy-acridin-9-yl)-acetic acid methyl ester::CHEMBL103975	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288549&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333056	104130120		CHEMBL103975				ZINC26821795	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480084	COC(=O)C(C(c1ccccc1)c1ccccc1)c1ccc2OCOc2c1	InChI=1S/C23H20O4/c1-25-23(24)22(18-12-13-19-20(14-18)27-15-26-19)21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-14,21-22H,15H2,1H3	PFQISMRUXMIYPF-UHFFFAOYSA-N	50288533	2-Benzo[1,3]dioxol-5-yl-3,3-diphenyl-propionic acid methyl ester::CHEMBL103969	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288533&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332856	104130104		CHEMBL103969				ZINC26820221	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480085	CC(C)(C)c1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1	InChI=1S/C33H29NO4/c1-33(2,3)23-15-12-21(13-16-23)19-36-32(35)30(22-14-17-28-29(18-22)38-20-37-28)31-24-8-4-6-10-26(24)34-27-11-7-5-9-25(27)31/h4-18,30H,19-20H2,1-3H3	AMWHTWLJFCHTAT-UHFFFAOYSA-N	50288555	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-tert-butyl-benzyl ester::CHEMBL319679	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288555&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332776	104130126		CHEMBL319679				ZINC26815850	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480091	COC(=O)C(c1ccc2OCOc2c1)c1c2ccccc2[n+]([O-])c2ccccc12	InChI=1S/C23H17NO5/c1-27-23(25)21(14-10-11-19-20(12-14)29-13-28-19)22-15-6-2-4-8-17(15)24(26)18-9-5-3-7-16(18)22/h2-12,21H,13H2,1H3	YBEOAYIBFDLFOR-UHFFFAOYSA-N	50288542	Benzo[1,3]dioxol-5-yl-(10-oxy-acridin-9-yl)-acetic acid methyl ester::CHEMBL102348	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288542&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44333055	104130113		CHEMBL102348				ZINC26818823	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480099	COC(=O)C(Cc1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C24H19NO4/c1-27-24(26)18(12-15-10-11-21-22(13-15)29-14-28-21)23-16-6-2-4-8-19(16)25-20-9-5-3-7-17(20)23/h2-11,13,18H,12,14H2,1H3	KXSQTEDQWJHEDB-UHFFFAOYSA-N	50288556	2-Acridin-9-yl-3-benzo[1,3]dioxol-5-yl-propionic acid methyl ester::CHEMBL100005	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288556&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332656	104130127		CHEMBL100005				ZINC26753052	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480106	COC(=O)C(c1ccc2OC(C)(C)Oc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C25H21NO4/c1-25(2)29-20-13-12-15(14-21(20)30-25)22(24(27)28-3)23-16-8-4-6-10-18(16)26-19-11-7-5-9-17(19)23/h4-14,22H,1-3H3	GTLRAUMURPBKNZ-UHFFFAOYSA-N	50288547	Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-acetic acid methyl ester::CHEMBL103572	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288547&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332823	104130118		CHEMBL103572				ZINC26818907	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50478987	Cc1noc(NS(=O)(=O)c2cccc3ccccc23)c1Br	InChI=1S/C14H11BrN2O3S/c1-9-13(15)14(20-16-9)17-21(18,19)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3	NUIMPHRVFJYACI-UHFFFAOYSA-N	50287995	CHEMBL80980::Naphthalene-1-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide	Endothelin-1 receptor			 110							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287995&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22616262	104129566		CHEMBL80980				ZINC26467445	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50478989	Cc1noc(NS(=O)(=O)c2ccc(Br)cc2)c1Br	InChI=1S/C10H8Br2N2O3S/c1-6-9(12)10(17-13-6)14-18(15,16)8-4-2-7(11)3-5-8/h2-5,14H,1H3	QGJVRRXWJMLVMT-UHFFFAOYSA-N	50287997	4-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL430822	Endothelin-1 receptor			 3000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287997&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617366	104129568		CHEMBL430822				ZINC26486509	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50478991	Cc1noc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1C	InChI=1S/C11H10Cl2N2O3S/c1-6-7(2)14-18-11(6)15-19(16,17)10-5-8(12)3-4-9(10)13/h3-5,15H,1-2H3	JVCIMCNGIOFJNL-UHFFFAOYSA-N	50287999	2,5-Dichloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL311455	Endothelin-1 receptor			 280							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287999&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3795752	104129570		CHEMBL311455				ZINC26486736	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50478992	Cc1noc(NS(=O)(=O)c2cccc(C)c2)c1Br	InChI=1S/C11H11BrN2O3S/c1-7-4-3-5-9(6-7)18(15,16)14-11-10(12)8(2)13-17-11/h3-6,14H,1-2H3	ZLGNIAQBPHBDCX-UHFFFAOYSA-N	50288000	CHEMBL312685::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3-methyl-benzenesulfonamide	Endothelin-1 receptor			 120							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288000&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617303	104129571		CHEMBL312685				ZINC26483382	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50478998	Cc1noc(NS(=O)(=O)c2ccccc2C)c1C	InChI=1S/C12H14N2O3S/c1-8-6-4-5-7-11(8)18(15,16)14-12-9(2)10(3)13-17-12/h4-7,14H,1-3H3	DWKQWJMAAYVRTO-UHFFFAOYSA-N	50288005	CHEMBL77090::N-(3,4-Dimethyl-isoxazol-5-yl)-2-methyl-benzenesulfonamide	Endothelin-1 receptor			 1000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288005&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316685	104129576		CHEMBL77090				ZINC26404611	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479001	Cc1noc(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1Br	InChI=1S/C10H7BrCl2N2O3S/c1-5-9(11)10(18-14-5)15-19(16,17)8-3-2-6(12)4-7(8)13/h2-4,15H,1H3	FOGSSEYMMHPPFH-UHFFFAOYSA-N	50288001	CHEMBL421523::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,4-dichloro-benzenesulfonamide	Endothelin-1 receptor			 2500							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288001&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617363	104129572		CHEMBL421523				ZINC26491476	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479002	Cc1noc(NS(=O)(=O)c2ccccc2)c1Cl	InChI=1S/C10H9ClN2O3S/c1-7-9(11)10(16-12-7)13-17(14,15)8-5-3-2-4-6-8/h2-6,13H,1H3	JHAHKJADRVGKDQ-UHFFFAOYSA-N	50288008	CHEMBL76860::N-(4-Chloro-3-methyl-isoxazol-5-yl)-benzenesulfonamide	Endothelin-1 receptor			 140							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288008&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22616257	104129579		CHEMBL76860				ZINC26404923	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479003	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2)c1C	InChI=1S/C17H16N2O3S/c1-12-13(2)18-22-17(12)19-23(20,21)16-11-7-6-10-15(16)14-8-4-3-5-9-14/h3-11,19H,1-2H3	SLBYWDJLJLBXGV-UHFFFAOYSA-N	50068700	Biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL310427	Endothelin-1 receptor			 8.3							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068700&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9840391	103962892		CHEMBL310427				ZINC00005864	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479004	Cc1noc(NS(=O)(=O)c2cccc(Cl)c2C)c1Br	InChI=1S/C11H10BrClN2O3S/c1-6-8(13)4-3-5-9(6)19(16,17)15-11-10(12)7(2)14-18-11/h3-5,15H,1-2H3	UXPAHOXAMUURFG-UHFFFAOYSA-N	50288009	CHEMBL78669::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3-chloro-2-methyl-benzenesulfonamide	Endothelin-1 receptor			 170							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288009&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617379	104129580		CHEMBL78669				ZINC26478057	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479005	Cc1noc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1Br	InChI=1S/C10H7BrCl2N2O3S/c1-5-9(11)10(18-14-5)15-19(16,17)6-2-3-7(12)8(13)4-6/h2-4,15H,1H3	PBPOTRLJYLWSKV-UHFFFAOYSA-N	50288003	CHEMBL80507::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3,4-dichloro-benzenesulfonamide	Endothelin-1 receptor			 550							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288003&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617354	104129574		CHEMBL80507				ZINC26468801	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479006	Cc1noc(NS(=O)(=O)c2ccccc2)c1C	InChI=1S/C11H12N2O3S/c1-8-9(2)12-16-11(8)13-17(14,15)10-6-4-3-5-7-10/h3-7,13H,1-2H3	XZUSGIGEWAJBBM-UHFFFAOYSA-N	50288010	CHEMBL312670::N-(3,4-Dimethyl-isoxazol-5-yl)-benzenesulfonamide	Endothelin-1 receptor			 500							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288010&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3370402	104129581		CHEMBL312670				ZINC06352348	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479007	COc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C11H10Br2N2O4S/c1-6-10(13)11(19-14-6)15-20(16,17)9-5-7(12)3-4-8(9)18-2/h3-5,15H,1-2H3	ZLOHPGJKHJCBHZ-UHFFFAOYSA-N	50288011	5-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-2-methoxy-benzenesulfonamide::CHEMBL312187	Endothelin-1 receptor			 72							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288011&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617333	104129582		CHEMBL312187				ZINC26482548	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479009	Cc1noc(NS(=O)(=O)c2ccccc2Cl)c1C	InChI=1S/C11H11ClN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-6-4-3-5-9(10)12/h3-6,14H,1-2H3	CDSFIMJACVVWEX-UHFFFAOYSA-N	50288012	2-Chloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL308521	Endothelin-1 receptor			 980							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288012&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316686	104129583		CHEMBL308521				ZINC26404614	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479010	CCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C12H12Br2N2O3S/c1-3-8-4-5-9(13)6-10(8)20(17,18)16-12-11(14)7(2)15-19-12/h4-6,16H,3H2,1-2H3	LHFACMLRLIZFFO-UHFFFAOYSA-N	50288013	5-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-2-ethyl-benzenesulfonamide::CHEMBL309692	Endothelin-1 receptor			 2.8							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288013&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9888574	104129584		CHEMBL309692				ZINC00600336	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479011	Cc1noc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c1Br	InChI=1S/C10H7BrCl2N2O3S/c1-5-9(11)10(18-14-5)15-19(16,17)8-3-6(12)2-7(13)4-8/h2-4,15H,1H3	KGWZRCWOQCGAFF-UHFFFAOYSA-N	50288014	CHEMBL311461::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3,5-dichloro-benzenesulfonamide	Endothelin-1 receptor			 62							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288014&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617345	104129585		CHEMBL311461				ZINC26468797	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479012	Cc1noc(NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c1C	InChI=1S/C11H10Cl2N2O3S/c1-6-7(2)14-18-11(6)15-19(16,17)10-4-8(12)3-9(13)5-10/h3-5,15H,1-2H3	NOGPKEUHXUEEMB-UHFFFAOYSA-N	50288015	3,5-Dichloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL76949	Endothelin-1 receptor			 430							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288015&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44317005	104129586		CHEMBL76949				ZINC26404903	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479015	Cc1noc(NS(=O)(=O)c2ccccc2Br)c1Br	InChI=1S/C10H8Br2N2O3S/c1-6-9(12)10(17-13-6)14-18(15,16)8-5-3-2-4-7(8)11/h2-5,14H,1H3	OHDADZJUNZPHRL-UHFFFAOYSA-N	50288017	2-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL312266	Endothelin-1 receptor			 40							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288017&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617318	104129588		CHEMBL312266				ZINC26473946	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479016	Cc1noc(NS(=O)(=O)c2ccc(C)cc2)c1Br	InChI=1S/C11H11BrN2O3S/c1-7-3-5-9(6-4-7)18(15,16)14-11-10(12)8(2)13-17-11/h3-6,14H,1-2H3	PSNNZVYJOZXYSK-UHFFFAOYSA-N	50288018	CHEMBL76438::N-(4-Bromo-3-methyl-isoxazol-5-yl)-4-methyl-benzenesulfonamide	Endothelin-1 receptor			 1400							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288018&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617355	104129589		CHEMBL76438				ZINC26404639	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479018	Cc1[n-][o+]c(NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)c1C	InChI=1S/C11H11N3O5S/c1-7-8(2)12-19-11(7)13-20(17,18)10-5-3-4-9(6-10)14(15)16/h3-6,13H,1-2H3	RUYBDUKVNBPRGC-UHFFFAOYSA-N	50034477	CHEMBL25970::N-(3,4-Dimethyl-isoxazol-5-yl)-3-nitro-benzenesulfonamide	Endothelin-1 receptor			 14000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034477&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10334781	103942678		CHEMBL25970				ZINC13741046	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479019	Cc1noc(NS(=O)(=O)c2cccc3ccccc23)c1C	InChI=1S/C15H14N2O3S/c1-10-11(2)16-20-15(10)17-21(18,19)14-9-5-7-12-6-3-4-8-13(12)14/h3-9,17H,1-2H3	ZEOXLCVRBAOHIV-UHFFFAOYSA-N	50034446	CHEMBL27065::Naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide	Endothelin-1 receptor			 440							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034446&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10357554	103942647		CHEMBL27065				ZINC13602327	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479022	Cc1noc(NS(=O)(=O)c2ccc(Cl)cc2)c1C	InChI=1S/C11H11ClN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,1-2H3	WAVGFLOYJLOYFK-UHFFFAOYSA-N	50288021	4-Chloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL78601	Endothelin-1 receptor			 10000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288021&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617385	104129592		CHEMBL78601				ZINC26483377	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479024	Cc1noc(NS(=O)(=O)c2ccccc2F)c1Br	InChI=1S/C10H8BrFN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-5-3-2-4-7(8)12/h2-5,14H,1H3	ROZIFONKJKKVJE-UHFFFAOYSA-N	50288022	CHEMBL310361::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2-fluoro-benzenesulfonamide	Endothelin-1 receptor			 160							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288022	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288022&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617302	104129593		CHEMBL310361				ZINC26471609	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479025	CCc1ccc(CC)c(c1)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C15H20N2O3S/c1-5-12-7-8-13(6-2)14(9-12)21(18,19)17-15-10(3)11(4)16-20-15/h7-9,17H,5-6H2,1-4H3	ZVVDJHXVMSJPFJ-UHFFFAOYSA-N	50288006	CHEMBL79066::N-(3,4-Dimethyl-isoxazol-5-yl)-2,5-diethyl-benzenesulfonamide	Endothelin-1 receptor			 27							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288006&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617393	104129577		CHEMBL79066				ZINC26482540	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479029	Cc1noc(NS(=O)(=O)c2c(C)cc(C)cc2C)c1C	InChI=1S/C14H18N2O3S/c1-8-6-9(2)13(10(3)7-8)20(17,18)16-14-11(4)12(5)15-19-14/h6-7,16H,1-5H3	XASGTXGCZRUMSA-UHFFFAOYSA-N	50288025	CHEMBL312372::N-(3,4-Dimethyl-isoxazol-5-yl)-2,4,6-trimethyl-benzenesulfonamide	Endothelin-1 receptor			 53000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288025&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617394	104129596		CHEMBL312372				ZINC26473377	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479030	Cc1noc(NS(=O)(=O)c2cccc(C)c2)c1C	InChI=1S/C12H14N2O3S/c1-8-5-4-6-11(7-8)18(15,16)14-12-9(2)10(3)13-17-12/h4-7,14H,1-3H3	SQCLRLTXWKEFAS-UHFFFAOYSA-N	50288026	CHEMBL76420::N-(3,4-Dimethyl-isoxazol-5-yl)-3-methyl-benzenesulfonamide	Endothelin-1 receptor			 720							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288026	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288026&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316994	104129597		CHEMBL76420				ZINC26404779	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479032	Cc1noc(NS(=O)(=O)c2ccc(C)cc2)c1C	InChI=1S/C12H14N2O3S/c1-8-4-6-11(7-5-8)18(15,16)14-12-9(2)10(3)13-17-12/h4-7,14H,1-3H3	JGXIRMJIDPMUJD-UHFFFAOYSA-N	50288028	CHEMBL78952::N-(3,4-Dimethyl-isoxazol-5-yl)-4-methyl-benzenesulfonamide	Endothelin-1 receptor			 4200							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288028&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44317215	104129599		CHEMBL78952				ZINC26485896	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479033	CCCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C14H17BrN2O3S/c1-4-5-11-6-7-12(15)8-13(11)21(18,19)17-14-9(2)10(3)16-20-14/h6-8,17H,4-5H2,1-3H3	XWNXSAKNQIGGHJ-UHFFFAOYSA-N	50287992	5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-propyl-benzenesulfonamide::CHEMBL311781	Endothelin-1 receptor			 16							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287992&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22616258	104129563		CHEMBL311781				ZINC26470688	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479034	CCc1ccc(Br)c(c1)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C13H15BrN2O3S/c1-4-10-5-6-11(14)12(7-10)20(17,18)16-13-8(2)9(3)15-19-13/h5-7,16H,4H2,1-3H3	UULNADYKRFTRFV-UHFFFAOYSA-N	50288029	2-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-5-ethyl-benzenesulfonamide::CHEMBL80807	Endothelin-1 receptor			 270							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288029&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316831	104129600		CHEMBL80807				ZINC26469908	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479035	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor			 5.8							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479036	Cc1noc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)c1C	InChI=1S/C17H16N2O3S/c1-12-13(2)18-22-17(12)19-23(20,21)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,19H,1-2H3	SZJKGOUNLCLNNW-UHFFFAOYSA-N	50288027	Biphenyl-4-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL311258	Endothelin-1 receptor			 9900							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288027&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453170	104129598		CHEMBL311258				ZINC26472566	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479037	Cc1noc(NS(=O)(=O)c2cc(Br)ccc2Br)c1Br	InChI=1S/C10H7Br3N2O3S/c1-5-9(13)10(18-14-5)15-19(16,17)8-4-6(11)2-3-7(8)12/h2-4,15H,1H3	MHBBBDQTHOUULU-UHFFFAOYSA-N	50288030	2,5-Dibromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL311216	Endothelin-1 receptor			 140							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288030&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44317109	104129601		CHEMBL311216				ZINC26472523	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479038	Cc1noc(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c1C	InChI=1S/C11H10Cl2N2O3S/c1-6-7(2)14-18-11(6)15-19(16,17)8-3-4-9(12)10(13)5-8/h3-5,15H,1-2H3	IZMALEQEGAIKHO-UHFFFAOYSA-N	50288031	3,4-Dichloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL76576	Endothelin-1 receptor			 3800							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288031&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617407	104129602		CHEMBL76576				ZINC26404905	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479039	CCc1ccc(Br)c(c1)S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C12H12Br2N2O3S/c1-3-8-4-5-9(13)10(6-8)20(17,18)16-12-11(14)7(2)15-19-12/h4-6,16H,3H2,1-2H3	YAVZYMOTSKGJQK-UHFFFAOYSA-N	50288032	2-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-5-ethyl-benzenesulfonamide::CHEMBL311742	Endothelin-1 receptor			 29							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288032&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617340	104129603		CHEMBL311742				ZINC26477248	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479040	Cc1noc(NS(=O)(=O)c2ccccc2Br)c1C	InChI=1S/C11H11BrN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-6-4-3-5-9(10)12/h3-6,14H,1-2H3	FICDMFJBLNFMAR-UHFFFAOYSA-N	50068725	2-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL80506	Endothelin-1 receptor			 620							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068725&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10711546	103962917		CHEMBL80506				ZINC00017024	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479041	Cc1noc(NS(=O)(=O)c2cccc(Br)c2)c1C	InChI=1S/C11H11BrN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-4-9(12)6-10/h3-6,14H,1-2H3	NHQICARTMJUSNL-UHFFFAOYSA-N	50288033	3-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL81593	Endothelin-1 receptor			 1800							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288033&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316973	104129604		CHEMBL81593				ZINC26486504	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479042	Cc1[n-][o+]c(NS(=O)(=O)c2cccc(c2)[N+]([O-])=O)c1Br	InChI=1S/C10H8BrN3O5S/c1-6-9(11)10(19-12-6)13-20(17,18)8-4-2-3-7(5-8)14(15)16/h2-5,13H,1H3	KQMKDYCUOBXWQB-UHFFFAOYSA-N	50288034	CHEMBL79030::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3-nitro-benzenesulfonamide	Endothelin-1 receptor			 2700							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288034&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617395	104129605		CHEMBL79030				ZINC26474629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479044	Cc1noc(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1C	InChI=1S/C11H10Cl2N2O3S/c1-6-7(2)14-18-11(6)15-19(16,17)10-4-3-8(12)5-9(10)13/h3-5,15H,1-2H3	BKOUWZNEIBPFLN-UHFFFAOYSA-N	50287998	2,4-Dichloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL79054	Endothelin-1 receptor			 14000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287998&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617299	104129569		CHEMBL79054				ZINC26478725	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479048	Cc1noc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)c1Cl	InChI=1S/C16H13ClN2O3S/c1-11-15(17)16(22-18-11)19-23(20,21)14-9-5-8-13(10-14)12-6-3-2-4-7-12/h2-10,19H,1H3	MBUKSPHJVDZOKR-UHFFFAOYSA-N	50288037	Biphenyl-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL311510	Endothelin-1 receptor			 160							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288037&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453180	104129608		CHEMBL311510				ZINC26469697	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479049	Cc1noc(NS(=O)(=O)c2ccc(F)cc2)c1C	InChI=1S/C11H11FN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,1-2H3	LTIZWYZGXKZSHV-UHFFFAOYSA-N	50034459	CHEMBL26522::N-(3,4-Dimethyl-isoxazol-5-yl)-4-fluoro-benzenesulfonamide	Endothelin-1 receptor			 6700							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034459&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10265127	103942660		CHEMBL26522				ZINC13741043	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479051	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2)c1Br	InChI=1S/C16H13BrN2O3S/c1-11-15(17)16(22-18-11)19-23(20,21)14-10-6-5-9-13(14)12-7-3-2-4-8-12/h2-10,19H,1H3	JNBSJLZGQLLABB-UHFFFAOYSA-N	50288038	Biphenyl-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL80857	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288038&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453177	104129609		CHEMBL80857				ZINC01540808	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479052	Cc1noc(NS(=O)(=O)c2cc(Br)ccc2C)c1Br	InChI=1S/C11H10Br2N2O3S/c1-6-3-4-8(12)5-9(6)19(16,17)15-11-10(13)7(2)14-18-11/h3-5,15H,1-2H3	XFMGYOLEYYPMEY-UHFFFAOYSA-N	50288016	5-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-2-methyl-benzenesulfonamide::CHEMBL420029	Endothelin-1 receptor			 240							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288016&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617389	104129587		CHEMBL420029				ZINC26475466	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479058	CCc1ccc(CC)c(c1)S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C14H17BrN2O3S/c1-4-10-6-7-11(5-2)12(8-10)21(18,19)17-14-13(15)9(3)16-20-14/h6-8,17H,4-5H2,1-3H3	OSBWUJAIYSBBKS-UHFFFAOYSA-N	50288007	CHEMBL311138::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,5-diethyl-benzenesulfonamide	Endothelin-1 receptor			 6.2							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10429404	104129578		CHEMBL311138				ZINC01540806	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479062	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2)c1Cl	InChI=1S/C16H13ClN2O3S/c1-11-15(17)16(22-18-11)19-23(20,21)14-10-6-5-9-13(14)12-7-3-2-4-8-12/h2-10,19H,1H3	UMHDNWCECBYHIF-UHFFFAOYSA-N	50288040	Biphenyl-2-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::CHEMBL310739	Endothelin-1 receptor			 3.8							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288040&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453178	104129611		CHEMBL310739				ZINC00019461	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479064	Cc1[n-][o+]c(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)c1C	InChI=1S/C11H11N3O5S/c1-7-8(2)12-19-11(7)13-20(17,18)10-5-3-9(4-6-10)14(15)16/h3-6,13H,1-2H3	UFDPLUYEUOHMIW-UHFFFAOYSA-N	50288044	CHEMBL80945::N-(3,4-Dimethyl-isoxazol-5-yl)-4-nitro-benzenesulfonamide	Endothelin-1 receptor			 90000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288044&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22616255	104129615		CHEMBL80945				ZINC26476663	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479068	Cc1noc(NS(=O)(=O)c2cc(C)ccc2C)c1C	InChI=1S/C13H16N2O3S/c1-8-5-6-9(2)12(7-8)19(16,17)15-13-10(3)11(4)14-18-13/h5-7,15H,1-4H3	PJUGXSRKEDNLKM-UHFFFAOYSA-N	50287993	CHEMBL80532::N-(3,4-Dimethyl-isoxazol-5-yl)-2,5-dimethyl-benzenesulfonamide	Endothelin-1 receptor			 270							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287993&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316527	104129564		CHEMBL80532				ZINC26469690	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479069	CCCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C13H14Br2N2O3S/c1-3-4-9-5-6-10(14)7-11(9)21(18,19)17-13-12(15)8(2)16-20-13/h5-7,17H,3-4H2,1-2H3	IPXMBZCQSUMHQH-UHFFFAOYSA-N	50288020	5-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-2-propyl-benzenesulfonamide::CHEMBL80342	Endothelin-1 receptor			 110							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288020&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10433234	104129591		CHEMBL80342				ZINC01485405	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479071	COc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C12H13BrN2O4S/c1-7-8(2)14-19-12(7)15-20(16,17)11-6-9(13)4-5-10(11)18-3/h4-6,15H,1-3H3	KGCZXCVHEKKOHY-UHFFFAOYSA-N	50288036	5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-methoxy-benzenesulfonamide::CHEMBL76779	Endothelin-1 receptor			 470							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288036&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316515	104129607		CHEMBL76779				ZINC26402350	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479072	CNc1ccc(C)cc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C12H14BrN3O3S/c1-7-4-5-9(14-3)10(6-7)20(17,18)16-12-11(13)8(2)15-19-12/h4-6,14,16H,1-3H3	KPISXONXINCUAB-UHFFFAOYSA-N	50288045	CHEMBL78563::N-(4-Bromo-3-methyl-isoxazol-5-yl)-5-methyl-2-methylamino-benzenesulfonamide	Endothelin-1 receptor			 8.1							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288045&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10383884	104129616		CHEMBL78563				ZINC01540807	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479074	Cc1noc(NS(=O)(=O)c2cccc(Br)c2)c1Br	InChI=1S/C10H8Br2N2O3S/c1-6-9(12)10(17-13-6)14-18(15,16)8-4-2-3-7(11)5-8/h2-5,14H,1H3	PDGKPKFRBQINFM-UHFFFAOYSA-N	50288046	3-Bromo-N-(4-bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL79031	Endothelin-1 receptor			 230							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288046&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617403	104129617		CHEMBL79031				ZINC26474642	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479075	Cc1noc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)c1Br	InChI=1S/C16H13BrN2O3S/c1-11-15(17)16(22-18-11)19-23(20,21)14-9-7-13(8-10-14)12-5-3-2-4-6-12/h2-10,19H,1H3	KMCRCRNDCWERHK-UHFFFAOYSA-N	50288047	Biphenyl-4-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL76623	Endothelin-1 receptor			 2900							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288047&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453172	104129618		CHEMBL76623				ZINC26404914	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479076	COc1ccc(cc1OC)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C13H16N2O5S/c1-8-9(2)14-20-13(8)15-21(16,17)10-5-6-11(18-3)12(7-10)19-4/h5-7,15H,1-4H3	UVXOCAAZEIJJRL-UHFFFAOYSA-N	50288048	CHEMBL310944::N-(3,4-Dimethyl-isoxazol-5-yl)-3,4-dimethoxy-benzenesulfonamide	Endothelin-1 receptor			 1900							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288048&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316983	104129619		CHEMBL310944				ZINC26479078	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479077	Cc1noc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)c1Br	InChI=1S/C16H13BrN2O3S/c1-11-15(17)16(22-18-11)19-23(20,21)14-9-5-8-13(10-14)12-6-3-2-4-7-12/h2-10,19H,1H3	MFSNNOLDVFKULH-UHFFFAOYSA-N	50288049	Biphenyl-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL80538	Endothelin-1 receptor			 120							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288049&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453179	104129620		CHEMBL80538				ZINC26473346	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479078	Cc1noc(NS(=O)(=O)c2ccccc2)c1Br	InChI=1S/C10H9BrN2O3S/c1-7-9(11)10(16-12-7)13-17(14,15)8-5-3-2-4-6-8/h2-6,13H,1H3	WAIXPTZIWAKDPT-UHFFFAOYSA-N	50288024	CHEMBL78080::N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide	Endothelin-1 receptor			 79							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288024&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617288	104129595		CHEMBL78080				ZINC26484753	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479082	Cc1noc(NS(=O)(=O)c2cc(C)ccc2C)c1Br	InChI=1S/C12H13BrN2O3S/c1-7-4-5-8(2)10(6-7)19(16,17)15-12-11(13)9(3)14-18-12/h4-6,15H,1-3H3	WTGDNWTUNLFQFJ-UHFFFAOYSA-N	50287994	CHEMBL80484::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,5-dimethyl-benzenesulfonamide	Endothelin-1 receptor			 44							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287994&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617377	104129565		CHEMBL80484				ZINC26470965	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479083	Cc1noc(NS(=O)(=O)c2cccc(Cl)c2C)c1C	InChI=1S/C12H13ClN2O3S/c1-7-9(3)14-18-12(7)15-19(16,17)11-6-4-5-10(13)8(11)2/h4-6,15H,1-3H3	LNYAMQUNDCLJNS-UHFFFAOYSA-N	50288050	3-Chloro-N-(3,4-dimethyl-isoxazol-5-yl)-2-methyl-benzenesulfonamide::CHEMBL312551	Endothelin-1 receptor			 990							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288050&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617381	104129621		CHEMBL312551				ZINC26476657	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479084	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C16H16BrN3O3S/c1-10-15(17)16(23-18-10)19-24(21,22)14-9-5-6-11-12(14)7-4-8-13(11)20(2)3/h4-9,19H,1-3H3	JRIBBCYNNHGXIT-UHFFFAOYSA-N	50288051	5-Dimethylamino-naphthalene-1-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL80782	Endothelin-1 receptor			 1.1							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288051&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9909467	104129622		CHEMBL80782				ZINC01540809	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479089	Cc1noc(NS(=O)(=O)c2cc(Br)ccc2C)c1C	InChI=1S/C12H13BrN2O3S/c1-7-4-5-10(13)6-11(7)19(16,17)15-12-8(2)9(3)14-18-12/h4-6,15H,1-3H3	NGXCMGIZCCARFM-UHFFFAOYSA-N	50288053	5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-methyl-benzenesulfonamide::CHEMBL80180	Endothelin-1 receptor			 840							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288053&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316526	104129624		CHEMBL80180				ZINC26469133	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479090	COc1ccc(cc1OC)S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C12H13BrN2O5S/c1-7-11(13)12(20-14-7)15-21(16,17)8-4-5-9(18-2)10(6-8)19-3/h4-6,15H,1-3H3	FDPWJZSWHSXSLF-UHFFFAOYSA-N	50288043	CHEMBL78853::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3,4-dimethoxy-benzenesulfonamide	Endothelin-1 receptor			 490							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288043&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453210	104129614		CHEMBL78853				ZINC26476705	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479091	Cc1noc(NS(=O)(=O)c2ccc(Br)cc2)c1C	InChI=1S/C11H11BrN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,1-2H3	LYUKKAPARIOLQD-UHFFFAOYSA-N	50287991	4-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL80129	Endothelin-1 receptor			 8900							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287991&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3811690	104129562		CHEMBL80129				ZINC26476669	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479094	Cc1noc(NS(=O)(=O)c2cccc(Cl)c2)c1C	InChI=1S/C11H11ClN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-4-9(12)6-10/h3-6,14H,1-2H3	MWZVTJOKICBOTQ-UHFFFAOYSA-N	50288039	3-Chloro-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL76360	Endothelin-1 receptor			 1500							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288039&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316993	104129610		CHEMBL76360				ZINC26404776	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479096	Cc1noc(NS(=O)(=O)c2ccccc2Cl)c1Br	InChI=1S/C10H8BrClN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-5-3-2-4-7(8)12/h2-5,14H,1H3	YKMBONBMAQCVGU-UHFFFAOYSA-N	50288042	CHEMBL80438::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2-chloro-benzenesulfonamide	Endothelin-1 receptor			 71							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288042&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617322	104129613		CHEMBL80438				ZINC26473953	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479099	Cc1noc(NS(=O)(=O)c2cc(Br)ccc2Br)c1C	InChI=1S/C11H10Br2N2O3S/c1-6-7(2)14-18-11(6)15-19(16,17)10-5-8(12)3-4-9(10)13/h3-5,15H,1-2H3	TUQYOPLCKKDDQY-UHFFFAOYSA-N	50288052	2,5-Dibromo-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL80317	Endothelin-1 receptor			 490							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288052&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316458	104129623		CHEMBL80317				ZINC26474090	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479100	Cc1noc(NS(=O)(=O)c2cccc(Cl)c2)c1Br	InChI=1S/C10H8BrClN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-4-2-3-7(12)5-8/h2-5,14H,1H3	KZMQHIBFSGTCHI-UHFFFAOYSA-N	50287996	CHEMBL80808::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3-chloro-benzenesulfonamide	Endothelin-1 receptor			 230							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287996&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617374	104129567		CHEMBL80808				ZINC26469915	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479102	Cc1[n-][o+]c(NS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)c1Br	InChI=1S/C10H8BrN3O5S/c1-6-9(11)10(19-12-6)13-20(17,18)8-4-2-7(3-5-8)14(15)16/h2-5,13H,1H3	WBNIPOYXTLRYMD-UHFFFAOYSA-N	50288041	CHEMBL79080::N-(4-Bromo-3-methyl-isoxazol-5-yl)-4-nitro-benzenesulfonamide	Endothelin-1 receptor			 19000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288041&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617344	104129612		CHEMBL79080				ZINC26478803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479103	CCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C13H15BrN2O3S/c1-4-10-5-6-11(14)7-12(10)20(17,18)16-13-8(2)9(3)15-19-13/h5-7,16H,4H2,1-3H3	JXCXAVJWSVRLGZ-UHFFFAOYSA-N	50288002	5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-ethyl-benzenesulfonamide::CHEMBL78830	Endothelin-1 receptor			 53							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288002&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44316768	104129573		CHEMBL78830				ZINC26482533	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479104	Cc1noc(NS(=O)(=O)c2ccccc2C)c1Br	InChI=1S/C11H11BrN2O3S/c1-7-5-3-4-6-9(7)18(15,16)14-11-10(12)8(2)13-17-11/h3-6,14H,1-2H3	DSNNFNGZIRHJEK-UHFFFAOYSA-N	50288035	CHEMBL78929::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2-methyl-benzenesulfonamide	Endothelin-1 receptor			 140							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288035&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617327	104129606		CHEMBL78929				ZINC26478964	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479105	Cc1noc(NS(=O)(=O)c2ccc(Cl)cc2)c1Br	InChI=1S/C10H8BrClN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-4-2-7(12)3-5-8/h2-5,14H,1H3	SFQDXKJHXJMGNZ-UHFFFAOYSA-N	50288054	CHEMBL78552::N-(4-Bromo-3-methyl-isoxazol-5-yl)-4-chloro-benzenesulfonamide	Endothelin-1 receptor			 2000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288054&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617284	104129625		CHEMBL78552				ZINC26480604	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479113	Cc1noc(NS(=O)(=O)c2cc(Cl)ccc2Cl)c1Br	InChI=1S/C10H7BrCl2N2O3S/c1-5-9(11)10(18-14-5)15-19(16,17)8-4-6(12)2-3-7(8)13/h2-4,15H,1H3	KLVAVDXAWNBCNZ-UHFFFAOYSA-N	50288004	CHEMBL309397::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,5-dichloro-benzenesulfonamide	Endothelin-1 receptor			 110							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288004&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617351	104129575		CHEMBL309397				ZINC26466548	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479114	Cc1noc(NS(=O)(=O)c2ccccc2F)c1C	InChI=1S/C11H11FN2O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-6-4-3-5-9(10)12/h3-6,14H,1-2H3	RZRSCFPIKIODFH-UHFFFAOYSA-N	50068745	CHEMBL78499::N-(3,4-Dimethyl-isoxazol-5-yl)-2-fluoro-benzenesulfonamide	Endothelin-1 receptor			 770							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068745&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10516176	103962937		CHEMBL78499				ZINC13782405	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479115	Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C	InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3	NHUHCSRWZMLRLA-UHFFFAOYSA-N	50034452	4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL453::Eryzole::Gantrisin::Pediazole::SULFISOXAZOLE::Sosol::Soxazole::Sulfafurazole::Sulfalar::Sulfisoxazol::Sulphafurazole::Sulsoxin	Endothelin-1 receptor			 850							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034452&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5344	103942653	102484	CHEMBL453	DB00263		C07318	ZINC96006009	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479116	Cc1noc(NS(=O)(=O)c2cccc(c2)-c2ccccc2)c1C	InChI=1S/C17H16N2O3S/c1-12-13(2)18-22-17(12)19-23(20,21)16-10-6-9-15(11-16)14-7-4-3-5-8-14/h3-11,19H,1-2H3	PFKPCLJGCDINDK-UHFFFAOYSA-N	50034473	Biphenyl-3-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL417651	Endothelin-1 receptor			 580							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034473&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10426645	103942674		CHEMBL417651				ZINC13741045	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479117	Cc1noc(NS(=O)(=O)c2ccc(F)cc2)c1Br	InChI=1S/C10H8BrFN2O3S/c1-6-9(11)10(17-13-6)14-18(15,16)8-4-2-7(12)3-5-8/h2-5,14H,1H3	VJXOLPMUQSVAKR-UHFFFAOYSA-N	50288019	CHEMBL78734::N-(4-Bromo-3-methyl-isoxazol-5-yl)-4-fluoro-benzenesulfonamide	Endothelin-1 receptor			 13000							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288019&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18617314	104129590		CHEMBL78734				ZINC26478266	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50479119	Cc1noc(NS(=O)(=O)c2c(C)cc(C)cc2C)c1Br	InChI=1S/C13H15BrN2O3S/c1-7-5-8(2)12(9(3)6-7)20(17,18)16-13-11(14)10(4)15-19-13/h5-6,16H,1-4H3	ITWYSOIYYHELQO-UHFFFAOYSA-N	50288023	CHEMBL77962::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,4,6-trimethyl-benzenesulfonamide	Endothelin-1 receptor			 5900							ChEMBL	10.1016/0960-894X(96)00441-6	10.7270/Q22V2G3R				Chan, MF; Raju, B; Kois, A; Castillo, RS; Verner, EJ; Wu, C; Hwang, E; Okun, I; Stavros, F; Balaji, VN	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288023	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288023&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15453209	104129594		CHEMBL77962				ZINC26483173	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481399	OC(=O)c1c(-c2ccc3OCOc3c2)c2cc(OCc3ccccc3)ccc2n1-c1ccc2OCOc2c1	InChI=1S/C30H21NO7/c32-30(33)29-28(19-6-10-24-26(12-19)37-16-35-24)22-14-21(34-15-18-4-2-1-3-5-18)8-9-23(22)31(29)20-7-11-25-27(13-20)38-17-36-25/h1-14H,15-17H2,(H,32,33)	XJEFQVHNUODKBN-UHFFFAOYSA-N	50289218	1,3-Bis-benzo[1,3]dioxol-5-yl-5-benzyloxy-1H-indole-2-carboxylic acid::CHEMBL10136	Endothelin-1 receptor			 1300							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289218&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266595	104130789		CHEMBL10136				ZINC26004615	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481405	OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n1Cc1ccccc1	InChI=1S/C23H17NO4/c25-23(26)22-21(16-10-11-19-20(12-16)28-14-27-19)17-8-4-5-9-18(17)24(22)13-15-6-2-1-3-7-15/h1-12H,13-14H2,(H,25,26)	WWKGLBHTXYOGOC-UHFFFAOYSA-N	50289219	3-Benzo[1,3]dioxol-5-yl-1-benzyl-1H-indole-2-carboxylic acid::CHEMBL10750	Endothelin-1 receptor			 11000							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289219&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266538	104130790		CHEMBL10750				ZINC26010843	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481408	COc1cccc(c1)-c1c(C(O)=O)n(-c2ccc3OCOc3c2)c2ccc(OC)cc12	InChI=1S/C24H19NO6/c1-28-16-5-3-4-14(10-16)22-18-12-17(29-2)7-8-19(18)25(23(22)24(26)27)15-6-9-20-21(11-15)31-13-30-20/h3-12H,13H2,1-2H3,(H,26,27)	ZNONZUGWGQAXGQ-UHFFFAOYSA-N	50289223	1-Benzo[1,3]dioxol-5-yl-5-methoxy-3-(3-methoxy-phenyl)-1H-indole-2-carboxylic acid::CHEMBL10388	Endothelin-1 receptor			 5500							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289223	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289223&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266628	104130794		CHEMBL10388				ZINC26007579	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481412	COc1ccc2n(c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1)-c1ccc2OCOc2c1	InChI=1S/C24H17NO7/c1-28-15-4-5-17-16(10-15)22(13-2-6-18-20(8-13)31-11-29-18)23(24(26)27)25(17)14-3-7-19-21(9-14)32-12-30-19/h2-10H,11-12H2,1H3,(H,26,27)	QVBGHNXDORISAP-UHFFFAOYSA-N	50289226	1,3-Bis-benzo[1,3]dioxol-5-yl-5-methoxy-1H-indole-2-carboxylic acid::CHEMBL10699	Endothelin-1 receptor			 260							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289226&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266592	104130797		CHEMBL10699				ZINC26007762	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481413	OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n1Cc1ccc2OCOc2c1	InChI=1S/C24H17NO6/c26-24(27)23-22(15-6-8-19-21(10-15)31-13-29-19)16-3-1-2-4-17(16)25(23)11-14-5-7-18-20(9-14)30-12-28-18/h1-10H,11-13H2,(H,26,27)	ARFKWLZSBLEADD-UHFFFAOYSA-N	50289227	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-1H-indole-2-carboxylic acid::CHEMBL416518	Endothelin-1 receptor			 1500							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289227&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266549	104130798		CHEMBL416518				ZINC26006096	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481414	COc1ccc2n(c(C(O)=O)c(-c3ccc(OC)c(OC)c3)c2c1)-c1ccc2OCOc2c1	InChI=1S/C25H21NO7/c1-29-16-6-7-18-17(12-16)23(14-4-8-19(30-2)21(10-14)31-3)24(25(27)28)26(18)15-5-9-20-22(11-15)33-13-32-20/h4-12H,13H2,1-3H3,(H,27,28)	SJNXUOVAWKQPAI-UHFFFAOYSA-N	50289228	1-Benzo[1,3]dioxol-5-yl-3-(3,4-dimethoxy-phenyl)-5-methoxy-1H-indole-2-carboxylic acid::CHEMBL10457	Endothelin-1 receptor			 1500							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289228&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266540	104130799		CHEMBL10457				ZINC26011105	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481416	OC(=O)c1c(-c2ccc3OCOc3c2)c2cc(Cl)ccc2n1-c1ccccc1	InChI=1S/C22H14ClNO4/c23-14-7-8-17-16(11-14)20(13-6-9-18-19(10-13)28-12-27-18)21(22(25)26)24(17)15-4-2-1-3-5-15/h1-11H,12H2,(H,25,26)	PEKHHFMAPLLVON-UHFFFAOYSA-N	50289230	3-Benzo[1,3]dioxol-5-yl-5-chloro-1-phenyl-1H-indole-2-carboxylic acid::CHEMBL273488	Endothelin-1 receptor			 10000							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289230&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266649	104130801		CHEMBL273488				ZINC26004965	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481417	OC(=O)c1c(-c2ccc3OCOc3c2)c2ccccc2n1-c1ccc2OCOc2c1	InChI=1S/C23H15NO6/c25-23(26)22-21(13-5-7-17-19(9-13)29-11-27-17)15-3-1-2-4-16(15)24(22)14-6-8-18-20(10-14)30-12-28-18/h1-10H,11-12H2,(H,25,26)	ZZRSXIKVCROVPL-UHFFFAOYSA-N	50289231	1,3-Bis-benzo[1,3]dioxol-5-yl-1H-indole-2-carboxylic acid::CHEMBL10211	Endothelin-1 receptor			 4100							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289231	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289231&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266532	104130802		CHEMBL10211				ZINC26006757	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481419	COc1ccc(cc1)-c1c(C(O)=O)n(-c2ccc3OCOc3c2)c2ccc(OCc3ccccc3)cc12	InChI=1S/C30H23NO6/c1-34-22-10-7-20(8-11-22)28-24-16-23(35-17-19-5-3-2-4-6-19)12-13-25(24)31(29(28)30(32)33)21-9-14-26-27(15-21)37-18-36-26/h2-16H,17-18H2,1H3,(H,32,33)	FDYWAWOHWCVFHZ-UHFFFAOYSA-N	50289233	1-Benzo[1,3]dioxol-5-yl-5-benzyloxy-3-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid::CHEMBL273410	Endothelin-1 receptor			 2400							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289233&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266568	104130804		CHEMBL273410				ZINC26006114	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481420	CCCOc1ccc2n(Cc3ccc4OCOc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1	InChI=1S/C27H23NO7/c1-2-9-31-18-5-6-20-19(12-18)25(17-4-8-22-24(11-17)35-15-33-22)26(27(29)30)28(20)13-16-3-7-21-23(10-16)34-14-32-21/h3-8,10-12H,2,9,13-15H2,1H3,(H,29,30)	LQWGCVIETCFLOP-UHFFFAOYSA-N	50069567	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL10218	Endothelin-1 receptor			 130							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069567&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266552	103963627		CHEMBL10218				ZINC26005428	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481423	COc1ccc(Cn2c(C(O)=O)c(-c3ccc4OCOc4c3)c3cc(OCc4ccccc4)ccc23)cc1	InChI=1S/C31H25NO6/c1-35-23-10-7-20(8-11-23)17-32-26-13-12-24(36-18-21-5-3-2-4-6-21)16-25(26)29(30(32)31(33)34)22-9-14-27-28(15-22)38-19-37-27/h2-16H,17-19H2,1H3,(H,33,34)	GTEPOVNRRKKMRR-UHFFFAOYSA-N	50289222	3-Benzo[1,3]dioxol-5-yl-5-benzyloxy-1-(4-methoxy-benzyl)-1H-indole-2-carboxylic acid::CHEMBL10092	Endothelin-1 receptor			 2700							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289222	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289222&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266537	104130793		CHEMBL10092				ZINC26005689	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481424	COc1cc2c(c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OCc1ccccc1)-c1ccc2OCOc2c1	InChI=1S/C32H25NO8/c1-36-26-13-22-23(14-29(26)37-16-19-5-3-2-4-6-19)33(15-20-7-9-24-27(11-20)40-17-38-24)31(32(34)35)30(22)21-8-10-25-28(12-21)41-18-39-25/h2-14H,15-18H2,1H3,(H,34,35)	BOQQYCYLUTYLGS-UHFFFAOYSA-N	50289221	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-1H-indole-2-carboxylic acid::CHEMBL10016	Endothelin-1 receptor			 30							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289221&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9850566	104130792		CHEMBL10016				ZINC01542796	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481425	OC(=O)c1c(-c2ccc3OCOc3c2)c2cc3OCOc3cc2n1Cc1ccc2OCOc2c1	InChI=1S/C25H17NO8/c27-25(28)24-23(14-2-4-18-20(6-14)32-11-30-18)15-7-21-22(34-12-33-21)8-16(15)26(24)9-13-1-3-17-19(5-13)31-10-29-17/h1-8H,9-12H2,(H,27,28)	PGDSQHCYBSJOHQ-UHFFFAOYSA-N	50289220	7-Benzo[1,3]dioxol-5-yl-5-benzo[1,3]dioxol-5-ylmethyl-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid::CHEMBL273529	Endothelin-1 receptor			 240							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289220&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266640	104130791		CHEMBL273529				ZINC26005301	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481426	COc1ccc(cc1)-n1c(C(O)=O)c(-c2ccc3OCOc3c2)c2cc(OC)ccc12	InChI=1S/C24H19NO6/c1-28-16-6-4-15(5-7-16)25-19-9-8-17(29-2)12-18(19)22(23(25)24(26)27)14-3-10-20-21(11-14)31-13-30-20/h3-12H,13H2,1-2H3,(H,26,27)	JUSDJOXOWICNLZ-UHFFFAOYSA-N	50289235	3-Benzo[1,3]dioxol-5-yl-5-methoxy-1-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid::CHEMBL9588	Endothelin-1 receptor			 3500							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266645	104130806		CHEMBL9588				ZINC26002837	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481430	COc1ccc(cc1OC)-c1c(C(O)=O)n(Cc2ccc3OCOc3c2)c2cc(OC)c(OC)cc12	InChI=1S/C27H25NO8/c1-31-19-8-6-16(10-21(19)32-2)25-17-11-22(33-3)23(34-4)12-18(17)28(26(25)27(29)30)13-15-5-7-20-24(9-15)36-14-35-20/h5-12H,13-14H2,1-4H3,(H,29,30)	OVPKPOGJHFVIFR-UHFFFAOYSA-N	50289224	1-Benzo[1,3]dioxol-5-ylmethyl-3-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL10019	Endothelin-1 receptor			 60							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289224&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266594	104130795		CHEMBL10019				ZINC26004607	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481431	CC(C)Oc1c(sc2ccc(OCc3ccccc3)cc12)C(O)=O	InChI=1S/C19H18O4S/c1-12(2)23-17-15-10-14(22-11-13-6-4-3-5-7-13)8-9-16(15)24-18(17)19(20)21/h3-10,12H,11H2,1-2H3,(H,20,21)	MFIHFDWJBWXRFD-UHFFFAOYSA-N	50287187	5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid::CHEMBL10143	Endothelin-1 receptor			 6000							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14673588	104128758		CHEMBL10143				ZINC26004833	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481432	OC(=O)c1c(-c2ccc3OCOc3c2)c2cc(OCc3ccccc3)ccc2n1Cc1ccc2OCOc2c1	InChI=1S/C31H23NO7/c33-31(34)30-29(21-7-11-26-28(13-21)39-18-37-26)23-14-22(35-16-19-4-2-1-3-5-19)8-9-24(23)32(30)15-20-6-10-25-27(12-20)38-17-36-25/h1-14H,15-18H2,(H,33,34)	KJKWFAMWOYDQGU-UHFFFAOYSA-N	50289237	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-benzyloxy-1H-indole-2-carboxylic acid::CHEMBL417246	Endothelin-1 receptor			 800							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289237&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266542	104130808		CHEMBL417246				ZINC26010126	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481433	COc1ccc2c(c(C(O)=O)n(-c3ccccc3)c2c1)-c1ccc2OCOc2c1	InChI=1S/C23H17NO5/c1-27-16-8-9-17-18(12-16)24(15-5-3-2-4-6-15)22(23(25)26)21(17)14-7-10-19-20(11-14)29-13-28-19/h2-12H,13H2,1H3,(H,25,26)	BLTDJTIBJOLYTK-UHFFFAOYSA-N	50289232	3-Benzo[1,3]dioxol-5-yl-6-methoxy-1-phenyl-1H-indole-2-carboxylic acid::CHEMBL276615	Endothelin-1 receptor			 7400							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289232&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266621	104130803		CHEMBL276615				ZINC26007202	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481435	COc1ccc2n(Cc3ccc4OCOc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1	InChI=1S/C25H19NO7/c1-29-16-4-5-18-17(10-16)23(15-3-7-20-22(9-15)33-13-31-20)24(25(27)28)26(18)11-14-2-6-19-21(8-14)32-12-30-19/h2-10H,11-13H2,1H3,(H,27,28)	ILZVJSNYGMVWLP-UHFFFAOYSA-N	50289236	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-methoxy-1H-indole-2-carboxylic acid::CHEMBL10523	Endothelin-1 receptor			 350							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289236	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289236&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266655	104130807		CHEMBL10523				ZINC26010386	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481436	CCCOc1ccc2n(c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1)-c1ccc2OCOc2c1	InChI=1S/C26H21NO7/c1-2-9-30-17-5-6-19-18(12-17)24(15-3-7-20-22(10-15)33-13-31-20)25(26(28)29)27(19)16-4-8-21-23(11-16)34-14-32-21/h3-8,10-12H,2,9,13-14H2,1H3,(H,28,29)	JNPFHSPAJLZJHE-UHFFFAOYSA-N	50289239	1,3-Bis-benzo[1,3]dioxol-5-yl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL10302	Endothelin-1 receptor			 43							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289239&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266575	104130810		CHEMBL10302				ZINC26006640	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481440	COc1ccc2n(c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1)-c1ccccc1	InChI=1S/C23H17NO5/c1-27-16-8-9-18-17(12-16)21(14-7-10-19-20(11-14)29-13-28-19)22(23(25)26)24(18)15-5-3-2-4-6-15/h2-12H,13H2,1H3,(H,25,26)	OBVDNWFVCACROJ-UHFFFAOYSA-N	50289225	3-Benzo[1,3]dioxol-5-yl-5-methoxy-1-phenyl-1H-indole-2-carboxylic acid::CHEMBL273258	Endothelin-1 receptor			 12000							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289225	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289225&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266654	104130796		CHEMBL273258				ZINC26004629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481441	COc1ccc(cc1)-n1c(C(O)=O)c(-c2ccc3OCOc3c2)c2ccccc12	InChI=1S/C23H17NO5/c1-27-16-9-7-15(8-10-16)24-18-5-3-2-4-17(18)21(22(24)23(25)26)14-6-11-19-20(12-14)29-13-28-19/h2-12H,13H2,1H3,(H,25,26)	DBJPCGMGGNNEAZ-UHFFFAOYSA-N	50289240	3-Benzo[1,3]dioxol-5-yl-1-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid::CHEMBL10151	Endothelin-1 receptor			 2300							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289240&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266629	104130811		CHEMBL10151				ZINC26005275	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481446	COc1cc2c(c(C(O)=O)n(Cc3ccc4OCOc4c3)c2cc1OC)-c1ccc2OCOc2c1	InChI=1S/C26H21NO8/c1-30-20-9-16-17(10-21(20)31-2)27(11-14-3-5-18-22(7-14)34-12-32-18)25(26(28)29)24(16)15-4-6-19-23(8-15)35-13-33-19/h3-10H,11-13H2,1-2H3,(H,28,29)	QXUMYHYMXFAQPE-UHFFFAOYSA-N	50069565	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL276638	Endothelin-1 receptor			 60							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069565&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266646	103963625		CHEMBL276638				ZINC26006962	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481452	COc1ccc(cc1)-c1c(C(O)=O)n(-c2ccc3OCOc3c2)c2ccc(OC)cc12	InChI=1S/C24H19NO6/c1-28-16-6-3-14(4-7-16)22-18-12-17(29-2)8-9-19(18)25(23(22)24(26)27)15-5-10-20-21(11-15)31-13-30-20/h3-12H,13H2,1-2H3,(H,26,27)	ALNZRBOFBJCSQN-UHFFFAOYSA-N	50289238	1-Benzo[1,3]dioxol-5-yl-5-methoxy-3-(4-methoxy-phenyl)-1H-indole-2-carboxylic acid::CHEMBL274370	Endothelin-1 receptor			 1100							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289238&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266565	104130809		CHEMBL274370				ZINC26006244	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50481453	COc1cc2c(c(C(O)=O)n(-c3ccc4OCOc4c3)c2cc1OC)-c1ccc2OCOc2c1	InChI=1S/C25H19NO8/c1-29-19-9-15-16(10-20(19)30-2)26(14-4-6-18-22(8-14)34-12-32-18)24(25(27)28)23(15)13-3-5-17-21(7-13)33-11-31-17/h3-10H,11-12H2,1-2H3,(H,27,28)	XSMIQRFUKYUGQY-UHFFFAOYSA-N	50289229	1,3-Bis-benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL274368	Endothelin-1 receptor			 80							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289229&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266567	104130800		CHEMBL274368				ZINC26005655	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471720	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)C(C)C)c1ccc2OCOc2c1	InChI=1S/C35H44N4O6S/c1-8-11-25-16-24(19-39-30(10-3)37-31-22(6)15-23(7)36-34(31)39)17-26(12-9-2)32(25)45-33(35(40)38-46(41,42)21(4)5)27-13-14-28-29(18-27)44-20-43-28/h13-18,21,33H,8-12,19-20H2,1-7H3,(H,38,40)	WSUPDCMKPUAGDA-UHFFFAOYSA-N	50284467	CHEMBL16018::Propane-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide	Endothelin-1 receptor			 700							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284467&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19010490	104126124		CHEMBL16018				ZINC49853629	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471722	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(C)(=O)=O)c1ccc2OCOc2c1	InChI=1S/C33H40N4O6S/c1-7-10-23-15-22(18-37-28(9-3)35-29-20(4)14-21(5)34-32(29)37)16-24(11-8-2)30(23)43-31(33(38)36-44(6,39)40)25-12-13-26-27(17-25)42-19-41-26/h12-17,31H,7-11,18-19H2,1-6H3,(H,36,38)	BZNIKCMSWPBYNN-UHFFFAOYSA-N	50284469	CHEMBL16197::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-methanesulfonamide	Endothelin-1 receptor			 500							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284469&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44211959	104126126		CHEMBL16197				ZINC14285474	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471724	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccc2OCOc2c1	InChI=1S/C32H37N3O5/c1-6-9-22-14-21(17-35-27(8-3)34-28-19(4)13-20(5)33-31(28)35)15-23(10-7-2)29(22)40-30(32(36)37)24-11-12-25-26(16-24)39-18-38-25/h11-16,30H,6-10,17-18H2,1-5H3,(H,36,37)	NNGHGYQUGDQKJY-UHFFFAOYSA-N	50284470	Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid::CHEMBL275179	Endothelin-1 receptor			 38							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284470&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19010493	104126127		CHEMBL275179				ZINC36238186	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471726	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H31N3O5/c1-5-7-20-13-19(15-32-25(6-2)31-26-17(3)12-18(4)30-28(26)32)8-10-22(20)37-27(29(33)34)21-9-11-23-24(14-21)36-16-35-23/h8-14,27H,5-7,15-16H2,1-4H3,(H,33,34)	CLHVJDANODTXIQ-UHFFFAOYSA-N	50284471	Benzo[1,3]dioxol-5-yl-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetic acid::CHEMBL16306	Endothelin-1 receptor			 840							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284471&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19010508	104126128		CHEMBL16306				ZINC36238190	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471727	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1cc(Br)c(OC)c(OC)c1Br	InChI=1S/C33H39Br2N3O5/c1-8-11-21-14-20(17-38-25(10-3)37-27-18(4)13-19(5)36-32(27)38)15-22(12-9-2)28(21)43-29(33(39)40)23-16-24(34)30(41-6)31(42-7)26(23)35/h13-16,29H,8-12,17H2,1-7H3,(H,39,40)	FJMSQNXGEWIXSJ-UHFFFAOYSA-N	50175515	(2,5-Dibromo-3,4-dimethoxy-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid::CHEMBL276819	Endothelin-1 receptor			 11000							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175515&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19385674	104061208		CHEMBL276819				ZINC49605971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471728	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C38H42N4O6S/c1-7-9-28-19-26(21-42-34(8-2)40-35-24(5)18-25(6)39-37(35)42)10-16-31(28)48-36(29-13-17-32-33(20-29)47-22-46-32)38(43)41-49(44,45)30-14-11-27(12-15-30)23(3)4/h10-20,23,36H,7-9,21-22H2,1-6H3,(H,41,43)	NTQWAQFOJQQOTK-UHFFFAOYSA-N	50117909	CHEMBL278176::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 24							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117909&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9896251	104011317		CHEMBL278176				ZINC43317880	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471729	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C41H48N4O6S/c1-8-11-30-20-28(23-45-36(10-3)43-37-26(6)19-27(7)42-40(37)45)21-31(12-9-2)38(30)51-39(32-15-18-34-35(22-32)50-24-49-34)41(46)44-52(47,48)33-16-13-29(14-17-33)25(4)5/h13-22,25,39H,8-12,23-24H2,1-7H3,(H,44,46)	XSNGSCKESCFFDT-UHFFFAOYSA-N	50284472	CHEMBL15573::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 330							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284472&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44270523	104126129		CHEMBL15573				ZINC49853632	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471730	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1	InChI=1S/C28H31N3O3/c1-5-10-22-16-20(13-14-23(22)34-26(28(32)33)21-11-8-7-9-12-21)17-31-24(6-2)30-25-18(3)15-19(4)29-27(25)31/h7-9,11-16,26H,5-6,10,17H2,1-4H3,(H,32,33)	IFUYEJOQMQZCAE-UHFFFAOYSA-N	50284444	CHEMBL15689::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-phenyl-acetic acid	Endothelin-1 receptor			 11000							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284444&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10095637	104126101		CHEMBL15689				ZINC13892670	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471731	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1ccc(CC(C)C)s1)c1ccc2OCOc2c1	InChI=1S/C40H48N4O6S2/c1-8-11-28-19-27(22-44-34(10-3)42-36-25(6)18-26(7)41-39(36)44)20-29(12-9-2)37(28)50-38(30-13-15-32-33(21-30)49-23-48-32)40(45)43-52(46,47)35-16-14-31(51-35)17-24(4)5/h13-16,18-21,24,38H,8-12,17,22-23H2,1-7H3,(H,43,45)	KRTXDXIJWFIGGJ-UHFFFAOYSA-N	50284466	5-Isobutyl-3H-1lambda*4*-thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide::CHEMBL15310	Endothelin-1 receptor			 600							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284466&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44270522	104126123		CHEMBL15310				ZINC49853634	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471735	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(CC(C)C)s1)c1ccc2OCOc2c1	InChI=1S/C37H42N4O6S2/c1-7-9-26-18-25(20-41-32(8-2)39-34-23(5)17-24(6)38-36(34)41)10-13-29(26)47-35(27-11-14-30-31(19-27)46-21-45-30)37(42)40-49(43,44)33-15-12-28(48-33)16-22(3)4/h10-15,17-19,22,35H,7-9,16,20-21H2,1-6H3,(H,40,42)	HDHCADXZMJNZJH-UHFFFAOYSA-N	50284468	5-Isobutyl-thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-amide::CHEMBL279419	Endothelin-1 receptor			 75							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284468&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44270498	104126125		CHEMBL279419				ZINC49605933	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471736	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1ccccc1)c1ccc2OCOc2c1	InChI=1S/C38H42N4O6S/c1-6-12-27-19-26(22-42-33(8-3)40-34-24(4)18-25(5)39-37(34)42)20-28(13-7-2)35(27)48-36(29-16-17-31-32(21-29)47-23-46-31)38(43)41-49(44,45)30-14-10-9-11-15-30/h9-11,14-21,36H,6-8,12-13,22-23H2,1-5H3,(H,41,43)	VPQXUAPGMAIEDK-UHFFFAOYSA-N	50284473	CHEMBL274243::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-benzenesulfonamide	Endothelin-1 receptor			 1600							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284473&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44270524	104126130		CHEMBL274243				ZINC49599986	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50471739	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(=O)NS(=O)(=O)c1cccs1)c1ccc2OCOc2c1	InChI=1S/C36H40N4O6S2/c1-6-10-25-17-24(20-40-30(8-3)38-32-22(4)16-23(5)37-35(32)40)18-26(11-7-2)33(25)46-34(27-13-14-28-29(19-27)45-21-44-28)36(41)39-48(42,43)31-12-9-15-47-31/h9,12-19,34H,6-8,10-11,20-21H2,1-5H3,(H,39,41)	OTPDSJIKVVZMFC-UHFFFAOYSA-N	50284474	3H-1lambda*4*-Thiophene-2-sulfonic acid {2-benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetyl}-amide::CHEMBL278930	Endothelin-1 receptor			 820							ChEMBL	10.1016/0960-894X(95)00186-W	10.7270/Q2DF6R5F				Walsh, TF; Fitch, KJ; Williams, DL; Murphy, KL; Nolan, NA; Pettibone, DJ; Chang, RS; O'Malley, SS; Clineschmidt, BV; Veber, DF; Greenlee, WJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284474&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44270602	104126131		CHEMBL278930				ZINC49605981	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486698	Cc1noc(NS(=O)(=O)c2sccc2COc2ccc(C)cc2)c1Br	InChI=1S/C16H15BrN2O4S2/c1-10-3-5-13(6-4-10)22-9-12-7-8-24-16(12)25(20,21)19-15-14(17)11(2)18-23-15/h3-8,19H,9H2,1-2H3	VUORJVHDOWDKQI-UHFFFAOYSA-N	50291472	3-p-Tolyloxymethyl-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL369359	Endothelin-1 receptor			 1640							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291472&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10478562	104133024		CHEMBL369359				ZINC28006561	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486699	Cc1noc(NS(=O)(=O)c2ccsc2COc2ccc(C)cc2C)c1Br	InChI=1S/C17H17BrN2O4S2/c1-10-4-5-13(11(2)8-10)23-9-14-15(6-7-25-14)26(21,22)20-17-16(18)12(3)19-24-17/h4-8,20H,9H2,1-3H3	PSFPUHKZCRACEN-UHFFFAOYSA-N	50291473	2-(2,4-Dimethyl-phenoxymethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL367776	Endothelin-1 receptor			 308							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291473&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445379	104133025		CHEMBL367776				ZINC13815842	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486701	Cc1noc(NS(=O)(=O)c2sccc2COc2ccc(C)cc2C)c1Br	InChI=1S/C17H17BrN2O4S2/c1-10-4-5-14(11(2)8-10)23-9-13-6-7-25-17(13)26(21,22)20-16-15(18)12(3)19-24-16/h4-8,20H,9H2,1-3H3	CULHDTXRYAAQLN-UHFFFAOYSA-N	50291475	3-(2,4-Dimethyl-phenoxymethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173805	Endothelin-1 receptor			 346							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291475&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445538	104133027		CHEMBL173805				ZINC28007079	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486703	Cc1noc(NS(=O)(=O)c2sccc2COc2ccc3OCOc3c2)c1Br	InChI=1S/C16H13BrN2O6S2/c1-9-14(17)15(25-18-9)19-27(20,21)16-10(4-5-26-16)7-22-11-2-3-12-13(6-11)24-8-23-12/h2-6,19H,7-8H2,1H3	HMIVSRRWRYUMJJ-UHFFFAOYSA-N	50291477	3-(Benzo[1,3]dioxol-5-yloxymethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173557	Endothelin-1 receptor			 513							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291477&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445523	104133029		CHEMBL173557				ZINC28008560	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486705	Cc1noc(NS(=O)(=O)c2ccsc2COc2cc3OCOc3cc2Cl)c1Br	InChI=1S/C16H12BrClN2O6S2/c1-8-15(17)16(26-19-8)20-28(21,22)14-2-3-27-13(14)6-23-10-5-12-11(4-9(10)18)24-7-25-12/h2-5,20H,6-7H2,1H3	DTRNHYYWARQBED-UHFFFAOYSA-N	50291476	2-(6-Chloro-benzo[1,3]dioxol-5-yloxymethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL352657	Endothelin-1 receptor			 129							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291476&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384177	104133028		CHEMBL352657				ZINC13815650	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486707	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)cc2C)c1Cl	InChI=1S/C18H18ClN3O4S2/c1-9-7-10(2)15(11(3)8-9)20-17(23)16-13(5-6-27-16)28(24,25)22-18-14(19)12(4)21-26-18/h5-8,22H,1-4H3,(H,20,23)	VMRGBLIETYGKNV-UHFFFAOYSA-N	50098772	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL277595	Endothelin-1 receptor			 0.630000							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098772&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10717923	103995742		CHEMBL277595				ZINC13560310	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486708	Cc1noc(NS(=O)(=O)c2ccsc2COc2ccc3OCOc3c2)c1Br	InChI=1S/C16H13BrN2O6S2/c1-9-15(17)16(25-18-9)19-27(20,21)14-4-5-26-13(14)7-22-10-2-3-11-12(6-10)24-8-23-11/h2-6,19H,7-8H2,1H3	PSJPXXLGYRBSEJ-UHFFFAOYSA-N	50291479	2-(Benzo[1,3]dioxol-5-yloxymethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL355800	Endothelin-1 receptor			 299							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291479&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445227	104133031		CHEMBL355800				ZINC28008607	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486709	Cc1noc(NS(=O)(=O)c2ccsc2COc2ccc(C)cc2)c1Br	InChI=1S/C16H15BrN2O4S2/c1-10-3-5-12(6-4-10)22-9-13-14(7-8-24-13)25(20,21)19-16-15(17)11(2)18-23-16/h3-8,19H,9H2,1-2H3	IEKGKMVSJIMMRX-UHFFFAOYSA-N	50291478	2-p-Tolyloxymethyl-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL172538	Endothelin-1 receptor			 1200							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291478&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445507	104133030		CHEMBL172538				ZINC13815693	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486713	Cc1noc(NS(=O)(=O)c2sccc2COc2c(C)cc(C)cc2C)c1Br	InChI=1S/C18H19BrN2O4S2/c1-10-7-11(2)16(12(3)8-10)24-9-14-5-6-26-18(14)27(22,23)21-17-15(19)13(4)20-25-17/h5-8,21H,9H2,1-4H3	KJBYBLYMXDYVRK-UHFFFAOYSA-N	50291474	3-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL424371	Endothelin-1 receptor			 54							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291474&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445313	104133026		CHEMBL424371				ZINC28019997	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486714	CCCc1cc2OCOc2cc1OCc1sccc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C19H19BrN2O6S2/c1-3-4-12-7-14-15(27-10-26-14)8-13(12)25-9-16-17(5-6-29-16)30(23,24)22-19-18(20)11(2)21-28-19/h5-8,22H,3-4,9-10H2,1-2H3	IISLJISTBMPEAA-UHFFFAOYSA-N	50291471	2-(6-Propyl-benzo[1,3]dioxol-5-yloxymethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL172666	Endothelin-1 receptor			 104							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291471&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22998456	104133023		CHEMBL172666				ZINC28016590	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486715	Cc1noc(NS(=O)(=O)c2ccsc2COc2c(C)cc(C)cc2C)c1Br	InChI=1S/C18H19BrN2O4S2/c1-10-7-11(2)17(12(3)8-10)24-9-14-15(5-6-26-14)27(22,23)21-18-16(19)13(4)20-25-18/h5-8,21H,9H2,1-4H3	KIFCJFDMMVRHIY-UHFFFAOYSA-N	50291481	2-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL367024	Endothelin-1 receptor			 62							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291481&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445457	104133033		CHEMBL367024				ZINC28008322	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486717	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc3OCOc3c2)c1Br	InChI=1S/C16H11BrN2O7S2/c1-8-13(17)15(26-18-8)19-28(21,22)12-4-5-27-14(12)16(20)25-9-2-3-10-11(6-9)24-7-23-10/h2-6,19H,7H2,1H3	JQBUPYPWHBIMNX-UHFFFAOYSA-N	50289945	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester::CHEMBL292802	Endothelin-1 receptor			 8.9							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289945&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9826741	104131516		CHEMBL292802				ZINC13815624	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486718	CCCc1cc2OCOc2cc1OCc1ccsc1S(=O)(=O)Nc1onc(C)c1Br	InChI=1S/C19H19BrN2O6S2/c1-3-4-12-7-15-16(27-10-26-15)8-14(12)25-9-13-5-6-29-19(13)30(23,24)22-18-17(20)11(2)21-28-18/h5-8,22H,3-4,9-10H2,1-2H3	UYISEVBBWJGYIL-UHFFFAOYSA-N	50291480	3-(6-Propyl-benzo[1,3]dioxol-5-yloxymethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL176538	Endothelin-1 receptor			 134							ChEMBL	10.1016/S0960-894X(97)00132-7	10.7270/Q2DV1JWM				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291480&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445537	104133032		CHEMBL176538				ZINC28019555	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486725	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2cc3OCOc3cc2CO)c1Br	InChI=1S/C18H15BrN2O6S2/c1-10-16(19)17(27-20-10)21-29(23,24)18-11(4-5-28-18)2-3-12-6-14-15(26-9-25-14)7-13(12)8-22/h2-7,21-22H,8-9H2,1H3/b3-2+	MEXKFSLYKSJPDY-NSCUHMNNSA-N	50291484	3-[2-(6-Hydroxymethyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL366680	Endothelin-1 receptor			 79							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291484&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384651	104133036		CHEMBL366680				ZINC28019861	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486726	Cc1noc(NS(=O)(=O)c2ccsc2CCc2ccc3OCOc3c2)c1Br	InChI=1S/C17H15BrN2O5S2/c1-10-16(18)17(25-19-10)20-27(21,22)15-6-7-26-14(15)5-3-11-2-4-12-13(8-11)24-9-23-12/h2,4,6-8,20H,3,5,9H2,1H3	MBZRSMYFGWYSRU-UHFFFAOYSA-N	50291485	2-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173982	Endothelin-1 receptor			 205							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291485&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445256	104133037		CHEMBL173982				ZINC13815672	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486728	Cc1noc(NS(=O)(=O)c2ccsc2COc2c(C)cc(C)cc2C)c1Br	InChI=1S/C18H19BrN2O4S2/c1-10-7-11(2)17(12(3)8-10)24-9-14-15(5-6-26-14)27(22,23)21-18-16(19)13(4)20-25-18/h5-8,21H,9H2,1-4H3	KIFCJFDMMVRHIY-UHFFFAOYSA-N	50291481	2-(2,4,6-Trimethyl-phenoxymethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL367024	Endothelin-1 receptor			 62000							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291481&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445457	104133033		CHEMBL367024				ZINC28008322	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486729	Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc3OCOc3c2)c1Br	InChI=1S/C17H15BrN2O5S2/c1-10-15(18)16(25-19-10)20-27(21,22)17-12(6-7-26-17)4-2-11-3-5-13-14(8-11)24-9-23-13/h3,5-8,20H,2,4,9H2,1H3	WIUBNUWPUWBVSS-UHFFFAOYSA-N	50291487	3-(2-Benzo[1,3]dioxol-5-yl-ethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL177070	Endothelin-1 receptor			 237							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291487&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445438	104133039		CHEMBL177070				ZINC28088049	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486732	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2c(C)cc(C)cc2C)c1Br	InChI=1S/C19H19BrN2O3S2/c1-11-9-12(2)16(13(3)10-11)6-5-15-7-8-26-19(15)27(23,24)22-18-17(20)14(4)21-25-18/h5-10,22H,1-4H3/b6-5+	IZJYSKBXILTXTE-AATRIKPKSA-N	50291490	3-[2-(2,4,6-Trimethyl-phenyl)-vinyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL172248	Endothelin-1 receptor			 53							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291490&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10344511	104133042		CHEMBL172248				ZINC28015962	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486733	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2cc3OCOc3cc2C)c1Br	InChI=1S/C18H15BrN2O5S2/c1-10-7-14-15(25-9-24-14)8-13(10)4-3-12-5-6-27-18(12)28(22,23)21-17-16(19)11(2)20-26-17/h3-8,21H,9H2,1-2H3/b4-3+	NNAQTUFNGOEBBT-ONEGZZNKSA-N	50291491	3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL176854	Endothelin-1 receptor			 72							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291491&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44385127	104133043		CHEMBL176854				ZINC28090266	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486735	Cc1noc(NS(=O)(=O)c2ccsc2\C=C\c2ccc(C)cc2)c1Br	InChI=1S/C17H15BrN2O3S2/c1-11-3-5-13(6-4-11)7-8-14-15(9-10-24-14)25(21,22)20-17-16(18)12(2)19-23-17/h3-10,20H,1-2H3/b8-7+	DAKTYJUJTJUDLB-BQYQJAHWSA-N	50291493	2-(2-p-Tolyl-vinyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL176422	Endothelin-1 receptor			 231							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291493&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445430	104133045		CHEMBL176422				ZINC13815737	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486736	Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc(C)cc2)c1Br	InChI=1S/C17H17BrN2O3S2/c1-11-3-5-13(6-4-11)7-8-14-9-10-24-17(14)25(21,22)20-16-15(18)12(2)19-23-16/h3-6,9-10,20H,7-8H2,1-2H3	JRGZXJBKZBEYCZ-UHFFFAOYSA-N	50291494	3-(2-p-Tolyl-ethyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL366364	Endothelin-1 receptor			 347							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291494&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445272	104133046		CHEMBL366364				ZINC28015434	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486739	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2ccc(C)cc2C)c1Br	InChI=1S/C18H17BrN2O3S2/c1-11-4-5-14(12(2)10-11)6-7-15-8-9-25-18(15)26(22,23)21-17-16(19)13(3)20-24-17/h4-10,21H,1-3H3/b7-6+	YILAMABQGCKEKO-VOTSOKGWSA-N	50291495	3-[2-(2,4-Dimethyl-phenyl)-vinyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL435346	Endothelin-1 receptor			 180							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291495&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383742	104133047		CHEMBL435346				ZINC28011366	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486740	Cc1noc(NS(=O)(=O)c2sccc2CCc2ccc(C)cc2C)c1Br	InChI=1S/C18H19BrN2O3S2/c1-11-4-5-14(12(2)10-11)6-7-15-8-9-25-18(15)26(22,23)21-17-16(19)13(3)20-24-17/h4-5,8-10,21H,6-7H2,1-3H3	BSUROEYVKLONPL-UHFFFAOYSA-N	50291496	3-[2-(2,4-Dimethyl-phenyl)-ethyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173189	Endothelin-1 receptor			 102							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291496&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445421	104133048		CHEMBL173189				ZINC28019258	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486744	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2cc3OCOc3cc2COC2CCOCC2)c1Br	InChI=1S/C23H23BrN2O7S2/c1-14-21(24)22(33-25-14)26-35(27,28)23-15(6-9-34-23)2-3-16-10-19-20(32-13-31-19)11-17(16)12-30-18-4-7-29-8-5-18/h2-3,6,9-11,18,26H,4-5,7-8,12-13H2,1H3/b3-2+	MLYKYTSBWJXONL-NSCUHMNNSA-N	50291498	3-{2-[6-(Tetrahydro-pyran-4-yloxymethyl)-benzo[1,3]dioxol-5-yl]-vinyl}-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL176675	Endothelin-1 receptor			 73							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291498&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384652	104133050		CHEMBL176675				ZINC28019866	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486745	Cc1noc(NS(=O)(=O)c2ccsc2CCc2ccc(C)cc2C)c1Br	InChI=1S/C18H19BrN2O3S2/c1-11-4-5-14(12(2)10-11)6-7-15-16(8-9-25-15)26(22,23)21-18-17(19)13(3)20-24-18/h4-5,8-10,21H,6-7H2,1-3H3	JLFJTRSJCFZVGY-UHFFFAOYSA-N	50291499	2-[2-(2,4-Dimethyl-phenyl)-ethyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL175045	Endothelin-1 receptor			 55							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291499&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445533	104133051		CHEMBL175045				ZINC13815857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486747	Cc1noc(NS(=O)(=O)c2ccsc2CCc2cc3OCOc3cc2C)c1Br	InChI=1S/C18H17BrN2O5S2/c1-10-7-13-14(25-9-24-13)8-12(10)3-4-15-16(5-6-27-15)28(22,23)21-18-17(19)11(2)20-26-18/h5-8,21H,3-4,9H2,1-2H3	LBPJEBLOIGXYMG-UHFFFAOYSA-N	50291486	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL368780	Endothelin-1 receptor			 62							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291486&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445304	104133038		CHEMBL368780				ZINC13815835	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486748	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2ccc(C)cc2)c1Br	InChI=1S/C17H15BrN2O3S2/c1-11-3-5-13(6-4-11)7-8-14-9-10-24-17(14)25(21,22)20-16-15(18)12(2)19-23-16/h3-10,20H,1-2H3/b8-7+	OQBDSYBMOYMTDC-BQYQJAHWSA-N	50291497	3-(2-p-Tolyl-vinyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL176912	Endothelin-1 receptor			 936							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291497&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445544	104133049		CHEMBL176912				ZINC28090273	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486750	Cc1noc(NS(=O)(=O)c2ccsc2\C=C\c2ccc3OCOc3c2)c1Br	InChI=1S/C17H13BrN2O5S2/c1-10-16(18)17(25-19-10)20-27(21,22)15-6-7-26-14(15)5-3-11-2-4-12-13(8-11)24-9-23-12/h2-8,20H,9H2,1H3/b5-3+	JYOXXRCVFNUFLQ-HWKANZROSA-N	50291492	2-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL367763	Endothelin-1 receptor			 141							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291492&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384656	104133044		CHEMBL367763				ZINC13815653	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486751	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2c(C)cc(C)cc2C)c1Cl	InChI=1S/C18H18ClN3O4S2/c1-9-7-10(2)15(11(3)8-9)20-17(23)16-13(5-6-27-16)28(24,25)22-18-14(19)12(4)21-26-18/h5-8,22H,1-4H3,(H,20,23)	VMRGBLIETYGKNV-UHFFFAOYSA-N	50098772	3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL277595	Endothelin-1 receptor			 630							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098772&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10717923	103995742		CHEMBL277595				ZINC13560310	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486753	Cc1noc(NS(=O)(=O)c2ccsc2\C=C\c2ccc(C)cc2C)c1Br	InChI=1S/C18H17BrN2O3S2/c1-11-4-5-14(12(2)10-11)6-7-15-16(8-9-25-15)26(22,23)21-18-17(19)13(3)20-24-18/h4-10,21H,1-3H3/b7-6+	MJRUDXHMLOPTDG-VOTSOKGWSA-N	50291483	2-[2-(2,4-Dimethyl-phenyl)-vinyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL172987	Endothelin-1 receptor			 166							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291483&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383754	104133035		CHEMBL172987				ZINC13815838	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486754	Cc1noc(NS(=O)(=O)c2ccsc2\C=C\c2cc3OCOc3cc2C)c1Br	InChI=1S/C18H15BrN2O5S2/c1-10-7-13-14(25-9-24-13)8-12(10)3-4-15-16(5-6-27-15)28(22,23)21-18-17(19)11(2)20-26-18/h3-8,21H,9H2,1-2H3/b4-3+	NCSPDGBPJJGGDT-ONEGZZNKSA-N	50291488	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL426218	Endothelin-1 receptor			 81							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291488&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44384757	104133040		CHEMBL426218				ZINC13815853	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486756	Cc1noc(NS(=O)(=O)c2ccsc2CCc2ccc(C)cc2)c1Br	InChI=1S/C17H17BrN2O3S2/c1-11-3-5-13(6-4-11)7-8-14-15(9-10-24-14)25(21,22)20-17-16(18)12(2)19-23-17/h3-6,9-10,20H,7-8H2,1-2H3	YRPDIYSYXUCGAU-UHFFFAOYSA-N	50291501	2-(2-p-Tolyl-ethyl)-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL174086	Endothelin-1 receptor			 106							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291501&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445593	104133053		CHEMBL174086				ZINC13815749	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486758	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Oc2ccc3OCOc3c2)c1Br	InChI=1S/C16H11BrN2O7S2/c1-8-13(17)15(26-18-8)19-28(21,22)12-4-5-27-14(12)16(20)25-9-2-3-10-11(6-9)24-7-23-10/h2-6,19H,7H2,1H3	JQBUPYPWHBIMNX-UHFFFAOYSA-N	50289945	3-(4-Bromo-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carboxylic acid benzo[1,3]dioxol-5-yl ester::CHEMBL292802	Endothelin-1 receptor			 8900							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289945&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9826741	104131516		CHEMBL292802				ZINC13815624	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486760	Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2ccc3OCOc3c2)c1Br	InChI=1S/C17H13BrN2O5S2/c1-10-15(18)16(25-19-10)20-27(21,22)17-12(6-7-26-17)4-2-11-3-5-13-14(8-11)24-9-23-13/h2-8,20H,9H2,1H3/b4-2+	DQEQKWIRFOZGIA-DUXPYHPUSA-N	50291502	3-(2-Benzo[1,3]dioxol-5-yl-vinyl)-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL174363	Endothelin-1 receptor			 218							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291502&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445458	104133054		CHEMBL174363				ZINC28011370	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486763	Cc1noc(NS(=O)(=O)c2sccc2CCc2c(C)cc(C)cc2C)c1Br	InChI=1S/C19H21BrN2O3S2/c1-11-9-12(2)16(13(3)10-11)6-5-15-7-8-26-19(15)27(23,24)22-18-17(20)14(4)21-25-18/h7-10,22H,5-6H2,1-4H3	UICXKCWFYWPAOT-UHFFFAOYSA-N	50291489	3-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173977	Endothelin-1 receptor			 58							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291489&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445336	104133041		CHEMBL173977				ZINC28009454	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486766	Cc1noc(NS(=O)(=O)c2ccsc2CCc2c(C)cc(C)cc2C)c1Br	InChI=1S/C19H21BrN2O3S2/c1-11-9-12(2)15(13(3)10-11)5-6-16-17(7-8-26-16)27(23,24)22-19-18(20)14(4)21-25-19/h7-10,22H,5-6H2,1-4H3	PSICFEQXOKBEBC-UHFFFAOYSA-N	50291503	2-[2-(2,4,6-Trimethyl-phenyl)-ethyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL171972	Endothelin-1 receptor			 46							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291503&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10479787	104133055		CHEMBL171972				ZINC28018360	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486769	Cc1noc(NS(=O)(=O)c2sccc2CCc2cc3OCOc3cc2C)c1Br	InChI=1S/C18H17BrN2O5S2/c1-10-7-14-15(25-9-24-14)8-13(10)4-3-12-5-6-27-18(12)28(22,23)21-17-16(19)11(2)20-26-17/h5-8,21H,3-4,9H2,1-2H3	DPFGKRGYAJNPCN-UHFFFAOYSA-N	50291500	3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-ethyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL366378	Endothelin-1 receptor			 91							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291500&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23445333	104133052		CHEMBL366378				ZINC28011854	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50486723	Cc1noc(NS(=O)(=O)c2ccsc2\C=C\c2c(C)cc(C)cc2C)c1Br	InChI=1S/C19H19BrN2O3S2/c1-11-9-12(2)15(13(3)10-11)5-6-16-17(7-8-26-16)27(23,24)22-19-18(20)14(4)21-25-19/h5-10,22H,1-4H3/b6-5+	CCUNAVNTYAROJU-AATRIKPKSA-N	50291482	2-[2-(2,4,6-Trimethyl-phenyl)-vinyl]-thiophene-3-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL173761	Endothelin-1 receptor			 44							ChEMBL	10.1016/S0960-894X(97)00133-9	10.7270/Q2959HKC				Raju, B; Okun, I; Stavros, F; Chan, MF	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291482&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383753	104133034		CHEMBL173761				ZINC28009460	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485836	COc1ccc(cc1)C1(OC(=O)N[C@@H](C)c2cccc3ccccc23)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C41H37NO10/c1-24(30-12-8-10-26-9-6-7-11-31(26)30)42-40(44)52-41(28-14-16-29(45-2)17-15-28)32(19-25-20-35(46-3)38(48-5)36(21-25)47-4)37(39(43)51-41)27-13-18-33-34(22-27)50-23-49-33/h6-18,20-22,24H,19,23H2,1-5H3,(H,42,44)/t24-,41?/m0/s1	FFJYBEOEJYDRNP-JDRJKRQWSA-N	50290979	((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yl ester::CHEMBL322920	Endothelin-1 receptor			 2							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290979&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332842	104132531		CHEMBL322920				ZINC26825975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485837	CCOC(=O)C(CC(C)C)NC(=O)OC1(OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1)c1ccc(OC)cc1	InChI=1S/C37H41NO12/c1-8-46-34(39)27(15-21(2)3)38-36(41)50-37(24-10-12-25(42-4)13-11-24)26(16-22-17-30(43-5)33(45-7)31(18-22)44-6)32(35(40)49-37)23-9-14-28-29(19-23)48-20-47-28/h9-14,17-19,21,27H,8,15-16,20H2,1-7H3,(H,38,41)	AGWINCPCXUTIHM-UHFFFAOYSA-N	50290980	2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-4-methyl-pentanoic acid ethyl ester::CHEMBL316523	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290980&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15411009	104132532		CHEMBL316523				ZINC26828178	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485838	CCOC(=O)CNC(=O)OC1(OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1)c1ccc(OC)cc1	InChI=1S/C33H33NO12/c1-6-42-28(35)17-34-32(37)46-33(21-8-10-22(38-2)11-9-21)23(13-19-14-26(39-3)30(41-5)27(15-19)40-4)29(31(36)45-33)20-7-12-24-25(16-20)44-18-43-24/h7-12,14-16H,6,13,17-18H2,1-5H3,(H,34,37)	CJWHCEUECPKIGE-UHFFFAOYSA-N	50290981	CHEMBL319452::PD-163140::[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-acetic acid ethyl ester	Endothelin-1 receptor			 0.350000							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290981&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9960931	104132533		CHEMBL319452				ZINC26822718	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485841	CCOC(=O)CCNC(=O)OC1(OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1)c1ccc(OC)cc1	InChI=1S/C34H35NO12/c1-6-43-29(36)13-14-35-33(38)47-34(22-8-10-23(39-2)11-9-22)24(15-20-16-27(40-3)31(42-5)28(17-20)41-4)30(32(37)46-34)21-7-12-25-26(18-21)45-19-44-25/h7-12,16-18H,6,13-15,19H2,1-5H3,(H,35,38)	XXSWBYWJOWKKDQ-UHFFFAOYSA-N	50290983	3-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-propionic acid ethyl ester::CHEMBL450337	Endothelin-1 receptor			 0.400000							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290983&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332735	104132535		CHEMBL450337				ZINC26820816	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485843	CCOC(=O)C(NC(=O)OC1(OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1)c1ccc(OC)cc1)C(C)C	InChI=1S/C36H39NO12/c1-8-45-34(39)31(20(2)3)37-35(40)49-36(23-10-12-24(41-4)13-11-23)25(15-21-16-28(42-5)32(44-7)29(17-21)43-6)30(33(38)48-36)22-9-14-26-27(18-22)47-19-46-26/h9-14,16-18,20,31H,8,15,19H2,1-7H3,(H,37,40)	YJIVLRXOOMLMDC-UHFFFAOYSA-N	50290984	2-[4-Benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yloxycarbonylamino]-3-methyl-butyric acid ethyl ester::CHEMBL103846	Endothelin-1 receptor			 0.600000							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290984&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15411005	104132536		CHEMBL103846				ZINC26820529	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485846	COc1ccc(cc1)C1(OC)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C26H22O6/c1-28-20-11-9-19(10-12-20)26(29-2)21(14-17-6-4-3-5-7-17)24(25(27)32-26)18-8-13-22-23(15-18)31-16-30-22/h3-13,15H,14,16H2,1-2H3	LSQBMBUQIJTXOS-UHFFFAOYSA-N	50057176	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-methoxy-5-(4-methoxy-phenyl)-5H-furan-2-one::CHEMBL276173	Endothelin-1 receptor			 300							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057176&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10717504	103953256		CHEMBL276173				ZINC13761554	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485847	COc1ccc(cc1)C1(O)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C28H26O9/c1-31-19-8-6-18(7-9-19)28(30)20(11-16-12-23(32-2)26(34-4)24(13-16)33-3)25(27(29)37-28)17-5-10-21-22(14-17)36-15-35-21/h5-10,12-14,30H,11,15H2,1-4H3	PWIPORDFWDZCJG-UHFFFAOYSA-N	50034267	3-(benzo[d][1,3]dioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-(3,4,5-trimethoxybenzyl)furan-2(5H)-one::3-Benzo[1,3]dioxol-5-yl-5-hydroxy-5-(4-methoxy-phenyl)-4-(3,4,5-trimethoxy-benzyl)-5H-furan-2-one::CHEMBL8981::PD-156707::PD156707	Endothelin-1 receptor			 0.370000							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9870830	103942468		CHEMBL8981				ZINC13740975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485848	COc1ccc(cc1)C1(OC(=O)NCC=C)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C32H31NO10/c1-6-13-33-31(35)43-32(21-8-10-22(36-2)11-9-21)23(14-19-15-26(37-3)29(39-5)27(16-19)38-4)28(30(34)42-32)20-7-12-24-25(17-20)41-18-40-24/h6-12,15-17H,1,13-14,18H2,2-5H3,(H,33,35)	CZRWRCWCSHNAHY-UHFFFAOYSA-N	50290982	Allyl-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yl ester::CHEMBL320839	Endothelin-1 receptor			 0.800000							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290982	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290982&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15411003	104132534		CHEMBL320839				ZINC26821619	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485853	CNC(=O)OC1(OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1)c1ccc(OC)cc1	InChI=1S/C30H29NO10/c1-31-29(33)41-30(19-7-9-20(34-2)10-8-19)21(12-17-13-24(35-3)27(37-5)25(14-17)36-4)26(28(32)40-30)18-6-11-22-23(15-18)39-16-38-22/h6-11,13-15H,12,16H2,1-5H3,(H,31,33)	OFDMTNIWJSEJHX-UHFFFAOYSA-N	50290986	CHEMBL320183::Methyl-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yl ester	Endothelin-1 receptor			 9							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290986	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290986&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15411002	104132538		CHEMBL320183				ZINC26822713	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50485854	COc1ccc(cc1)C1(OC(=O)N[C@@H](C)c2ccccc2)OC(=O)C(=C1Cc1ccccc1)c1ccc2OCOc2c1	InChI=1S/C34H29NO7/c1-22(24-11-7-4-8-12-24)35-33(37)42-34(26-14-16-27(38-2)17-15-26)28(19-23-9-5-3-6-10-23)31(32(36)41-34)25-13-18-29-30(20-25)40-21-39-29/h3-18,20,22H,19,21H2,1-2H3,(H,35,37)/t22-,34?/m0/s1	AVTITURLDNGPIM-DAXAVGQISA-N	50290985	((S)-1-Phenyl-ethyl)-carbamic acid 4-benzo[1,3]dioxol-5-yl-3-benzyl-2-(4-methoxy-phenyl)-5-oxo-2,5-dihydro-furan-2-yl ester::CHEMBL103501	Endothelin-1 receptor			 18							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290985&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15410997	104132537		CHEMBL103501				ZINC26820689	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50504203	COC[C@H](Cc1ccc(OC)c(OC)c1)[C@H](COC)Cc1ccc(OC)c(OC)c1	InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m0/s1	KFLQGJQSLUYUBF-PMACEKPBSA-N	50292477	CHEMBL453568::phyllanthin	Endothelin-1 receptor			>1000000							ChEMBL	10.1021/np50124a006	10.7270/Q2ST7PV5				Hussain, RA; Dickey, JK; Rosser, MP; Matson, JA; Kozlowski, MR; Brittain, RJ; Webb, ML; Rose, PM; Fernandes, P	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292477&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9953821	104134028		CHEMBL453568				ZINC05879645	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50504204	COC[C@@H]1Cc2cc(OC)c3OCOc3c2[C@@H]([C@H]1COC)c1ccc(OC)c(OC)c1	InChI=1S/C24H30O7/c1-25-11-16-8-15-10-20(29-5)23-24(31-13-30-23)22(15)21(17(16)12-26-2)14-6-7-18(27-3)19(9-14)28-4/h6-7,9-10,16-17,21H,8,11-13H2,1-5H3/t16-,17-,21+/m0/s1	LBJCUHLNHSKZBW-XGHQBKJUSA-N	50292475	CHEMBL510130::hypophyllanthin	Endothelin-1 receptor			 40000							ChEMBL	10.1021/np50124a006	10.7270/Q2ST7PV5				Hussain, RA; Dickey, JK; Rosser, MP; Matson, JA; Kozlowski, MR; Brittain, RJ; Webb, ML; Rose, PM; Fernandes, P	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292475&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			182140	104134026		CHEMBL510130				ZINC15778313	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50504205	COC[C@@H]1Cc2cc3OCOc3c(OC)c2[C@@H]([C@H]1COC)c1ccc(OC)c(OC)c1	InChI=1S/C24H30O7/c1-25-11-16-8-15-10-20-23(31-13-30-20)24(29-5)22(15)21(17(16)12-26-2)14-6-7-18(27-3)19(9-14)28-4/h6-7,9-10,16-17,21H,8,11-13H2,1-5H3/t16-,17-,21+/m0/s1	LHQDZANQXMRHIV-XGHQBKJUSA-N	50292476	CHEMBL453822::nirtetralin	Endothelin-1 receptor			 75000							ChEMBL	10.1021/np50124a006	10.7270/Q2ST7PV5				Hussain, RA; Dickey, JK; Rosser, MP; Matson, JA; Kozlowski, MR; Brittain, RJ; Webb, ML; Rose, PM; Fernandes, P	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292476&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10477792	104134027		CHEMBL453822				ZINC38940226	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50504209	COc1cc(C)c(OC)c2[C@@H](C[C@@H](Cc12)C(O)=O)c1ccccc1	InChI=1S/C20H22O4/c1-12-9-17(23-2)16-11-14(20(21)22)10-15(18(16)19(12)24-3)13-7-5-4-6-8-13/h4-9,14-15H,10-11H2,1-3H3,(H,21,22)/t14-,15-/m0/s1	HVWXAXKJRJHQDH-GJZGRUSLSA-N	50292478	(2S,4S)-5,8-dimethoxy-6-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid::CHEMBL453823	Endothelin-1 receptor			 160000							ChEMBL	10.1021/np50124a006	10.7270/Q2ST7PV5				Hussain, RA; Dickey, JK; Rosser, MP; Matson, JA; Kozlowski, MR; Brittain, RJ; Webb, ML; Rose, PM; Fernandes, P	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292478&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10336497	104134029		CHEMBL453823				ZINC38541376	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50587173	CC(=NOC(=O)Nc1ccccc1)c1cccc(c1)-c1cccs1	InChI=1S/C19H16N2O2S/c1-14(21-23-19(22)20-17-9-3-2-4-10-17)15-7-5-8-16(13-15)18-11-6-12-24-18/h2-13H,1H3,(H,20,22)	CQUWKHKELQQYRI-UHFFFAOYSA-N	50323040	1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime::CHEMBL1210154	Endothelin-1 receptor			>10000							ChEMBL	10.1016/j.bmcl.2010.06.050	10.7270/Q24Q7V5B	20591666			Gattinoni, S; Simone, CD; Dallavalle, S; Fezza, F; Nannei, R; Battista, N; Minetti, P; Quattrociocchi, G; Caprioli, A; Borsini, F; Cabri, W; Penco, S; Merlini, L; Maccarrone, M	Universit&#224; degli Studi di Milano	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323040&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44469677	117644361		CHEMBL1210154				ZINC58487725	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50598647	C[C@H]1Cc2c([nH]c3cc(Cl)c(F)cc23)[C@@]2(N1)C(=O)Nc1ccc(Cl)cc21	InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1	CKLPLPZSUQEDRT-WPCRTTGESA-N	50318666	(1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-tetrahydrospiro-[beta-carboline-1,3'-indol]-2'(1'H)-one::CHEMBL1082723::NITD609	Endothelin-1 receptor			>30000							ChEMBL	10.1126/science.1193225	10.7270/Q2SB45ZB	20813948			Rottmann, M; McNamara, C; Yeung, BK; Lee, MC; Zou, B; Russell, B; Seitz, P; Plouffe, DM; Dharia, NV; Tan, J; Cohen, SB; Spencer, KR; Gonzalez-Paez, GE; Lakshminarayana, SB; Goh, A; Suwanarusk, R; Jegla, T; Schmitt, EK; Beck, HP; Brun, R; Nosten, F; Renia, L; Dartois, V; Keller, TH; Fidock, DA; Winzeler, EA; Diagana, TT	Swiss Tropical and Public Health Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50318666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50318666&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44469321	104153027		CHEMBL1082723				ZINC49037032	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606555	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(O)ccc12	InChI=1S/C28H23NO8/c1-2-16-10-23-24(37-14-36-23)11-18(16)13-29-22-7-6-19(30)12-20(22)26(31)21(25(29)28(34)35)9-15-4-3-5-17(8-15)27(32)33/h3-8,10-12,30H,2,9,13-14H2,1H3,(H,32,33)(H,34,35)	FFJSPULNDJGPKT-UHFFFAOYSA-N	50329837	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-hydroxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272137	Endothelin-1 receptor			 38.9							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329837&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			24997097	123108952		CHEMBL1272137				ZINC64527159	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606556	CCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C30H27NO8/c1-3-18-12-25-26(39-16-38-25)13-20(18)15-31-24-9-8-21(37-4-2)14-22(24)28(32)23(27(31)30(35)36)11-17-6-5-7-19(10-17)29(33)34/h5-10,12-14H,3-4,11,15-16H2,1-2H3,(H,33,34)(H,35,36)	UWVSLXNFMJFARF-UHFFFAOYSA-N	50329838	3-(3-Carboxybenzyl)-6-ethoxy-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272190	Endothelin-1 receptor			 6.6							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329838&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943105	123108953		CHEMBL1272190				ZINC64526379	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606557	CCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C31H29NO8/c1-3-10-38-22-8-9-25-23(15-22)29(33)24(12-18-6-5-7-20(11-18)30(34)35)28(31(36)37)32(25)16-21-14-27-26(39-17-40-27)13-19(21)4-2/h5-9,11,13-15H,3-4,10,12,16-17H2,1-2H3,(H,34,35)(H,36,37)	JZVDVZMUHGSKGI-UHFFFAOYSA-N	50329839	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-6-propoxy-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272244	Endothelin-1 receptor			 0.11							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329839&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			25211074	123108954		CHEMBL1272244				ZINC59096876	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606558	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OC(C)C)ccc12	InChI=1S/C31H29NO8/c1-4-19-12-26-27(39-16-38-26)13-21(19)15-32-25-9-8-22(40-17(2)3)14-23(25)29(33)24(28(32)31(36)37)11-18-6-5-7-20(10-18)30(34)35/h5-10,12-14,17H,4,11,15-16H2,1-3H3,(H,34,35)(H,36,37)	WAOUMQDGIOSVAF-UHFFFAOYSA-N	50329840	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-isopropoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272299	Endothelin-1 receptor			 13.5							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329840&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630531	123108955		CHEMBL1272299				ZINC64527147	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606559	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC=C)ccc12	InChI=1S/C31H27NO8/c1-3-10-38-22-8-9-25-23(15-22)29(33)24(12-18-6-5-7-20(11-18)30(34)35)28(31(36)37)32(25)16-21-14-27-26(39-17-40-27)13-19(21)4-2/h3,5-9,11,13-15H,1,4,10,12,16-17H2,2H3,(H,34,35)(H,36,37)	YPYVZNCHGXISOT-UHFFFAOYSA-N	50329841	6-(Allyloxy)-3-(3-carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271479	Endothelin-1 receptor			 38.1							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329841&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630532	123108956		CHEMBL1271479				ZINC64513143	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606560	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCOC)ccc12	InChI=1S/C30H27NO9/c1-3-18-11-25-26(40-16-39-25)12-20(18)14-31-24-8-7-21(38-15-37-2)13-22(24)28(32)23(27(31)30(35)36)10-17-5-4-6-19(9-17)29(33)34/h4-9,11-13H,3,10,14-16H2,1-2H3,(H,33,34)(H,35,36)	GNUKWUWFLYQCGT-UHFFFAOYSA-N	50329842	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-(methoxymethoxy)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271531	Endothelin-1 receptor			 24.4							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329842&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630654	123108957		CHEMBL1271531				ZINC64513681	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606561	CCCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C32H31NO8/c1-3-5-11-39-23-9-10-26-24(16-23)30(34)25(13-19-7-6-8-21(12-19)31(35)36)29(32(37)38)33(26)17-22-15-28-27(40-18-41-28)14-20(22)4-2/h6-10,12,14-16H,3-5,11,13,17-18H2,1-2H3,(H,35,36)(H,37,38)	KAAWXPGZQHJMQL-UHFFFAOYSA-N	50329843	6-Butoxy-3-(3-carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271586	Endothelin-1 receptor			 1.44							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329843&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630655	123108958		CHEMBL1271586				ZINC64512459	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606562	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC(C)C)ccc12	InChI=1S/C32H31NO8/c1-4-20-12-27-28(41-17-40-27)13-22(20)15-33-26-9-8-23(39-16-18(2)3)14-24(26)30(34)25(29(33)32(37)38)11-19-6-5-7-21(10-19)31(35)36/h5-10,12-14,18H,4,11,15-17H2,1-3H3,(H,35,36)(H,37,38)	ASYDIUHFIWWNJR-UHFFFAOYSA-N	50329844	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-isobutoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271640	Endothelin-1 receptor			 6.3							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329844&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52949155	123108959		CHEMBL1271640				ZINC64513129	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606563	CCC(C)Oc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C32H31NO8/c1-4-18(3)41-23-9-10-26-24(15-23)30(34)25(12-19-7-6-8-21(11-19)31(35)36)29(32(37)38)33(26)16-22-14-28-27(39-17-40-28)13-20(22)5-2/h6-11,13-15,18H,4-5,12,16-17H2,1-3H3,(H,35,36)(H,37,38)	BLQQLPGJOJAEKZ-UHFFFAOYSA-N	50329845	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-sec-butoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271691	Endothelin-1 receptor			 9.9							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329845&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52944083	123108960		CHEMBL1271691				ZINC64539294	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606564	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC3CC3)ccc12	InChI=1S/C32H29NO8/c1-2-20-12-27-28(41-17-40-27)13-22(20)15-33-26-9-8-23(39-16-18-6-7-18)14-24(26)30(34)25(29(33)32(37)38)11-19-4-3-5-21(10-19)31(35)36/h3-5,8-10,12-14,18H,2,6-7,11,15-17H2,1H3,(H,35,36)(H,37,38)	HXUVUUFEMYJLDB-UHFFFAOYSA-N	50329846	3-(3-Carboxybenzyl)-6-(cyclopropylmethoxy)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271746	Endothelin-1 receptor			 115.9							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329846&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52949197	123108961		CHEMBL1271746				ZINC64539279	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606565	CCCCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C33H33NO8/c1-3-5-6-12-40-24-10-11-27-25(17-24)31(35)26(14-20-8-7-9-22(13-20)32(36)37)30(33(38)39)34(27)18-23-16-29-28(41-19-42-29)15-21(23)4-2/h7-11,13,15-17H,3-6,12,14,18-19H2,1-2H3,(H,36,37)(H,38,39)	UKUDNNUJALQAMV-UHFFFAOYSA-N	50329847	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-6-(pentyloxy)-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1269101	Endothelin-1 receptor			 610							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329847&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943235	123108962		CHEMBL1269101				ZINC64527302	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606566	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCCCO)ccc12	InChI=1S/C31H29NO9/c1-2-19-13-26-27(41-17-40-26)14-21(19)16-32-25-8-7-22(39-10-4-9-33)15-23(25)29(34)24(28(32)31(37)38)12-18-5-3-6-20(11-18)30(35)36/h3,5-8,11,13-15,33H,2,4,9-10,12,16-17H2,1H3,(H,35,36)(H,37,38)	LKDZAJCVVWLFTK-UHFFFAOYSA-N	50329848	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-(3-hydroxypropoxy)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271807	Endothelin-1 receptor			 7.4							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329848&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52944276	123108963		CHEMBL1271807				ZINC64527553	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606567	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC(O)=O)ccc12	InChI=1S/C30H25NO10/c1-2-17-10-24-25(41-15-40-24)11-19(17)13-31-23-7-6-20(39-14-26(32)33)12-21(23)28(34)22(27(31)30(37)38)9-16-4-3-5-18(8-16)29(35)36/h3-8,10-12H,2,9,13-15H2,1H3,(H,32,33)(H,35,36)(H,37,38)	PCEPXCZCOCDRRI-UHFFFAOYSA-N	50329849	3-(3-Carboxybenzyl)-6-(carboxymethoxy)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271863	Endothelin-1 receptor			 284.5							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329849&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52950137	123108964		CHEMBL1271863				ZINC64528091	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606568	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23-,24-,26+/m0/s1	VYCMAAOURFJIHD-AOYLRGCGSA-N	50329850	(R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-3-methyl-but-3-enylcarbamoyl}-2-methyl-propylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-butyric acid::2-((3R,6S,9R,12S,17aS)-9-((1H-indol-3-yl)methyl)-6-isobutyl-3-isopropyl-1,4,7,10,13-pentaoxohexadecahydro-1H-pyrrolo[1,2-a][1,4,7,10,13]pentaazacyclopentadecin-12-yl)acetic acid::CHEMBL1269102::[(1S,4R,5R)-8-(1H-Indol-3-ylmethyl)-11-((S)-isobutyl)-14-((R)-isopropyl)-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid::[(5R,8R,11S,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid::[(5R,8R,11S,14R,16aS)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid::[8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor			 24.8							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329850&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943236	123108965		CHEMBL1269102				ZINC60291636	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50606579	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2ccccc12	InChI=1S/C28H23NO7/c1-2-17-12-23-24(36-15-35-23)13-19(17)14-29-22-9-4-3-8-20(22)26(30)21(25(29)28(33)34)11-16-6-5-7-18(10-16)27(31)32/h3-10,12-13H,2,11,14-15H2,1H3,(H,31,32)(H,33,34)	YCDUZUIVJLJHQL-UHFFFAOYSA-N	50329851	3-(3-carboxybenzyl)-1-((6-ethylbenzo[d][1,3]dioxol-5-yl)methyl)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1204990	Endothelin-1 receptor			 0.69							ChEMBL	10.1016/j.bmcl.2010.08.074	10.7270/Q2X34XPP	20932745			Patel, HJ; Olgun, N; Lengyel, I; Reznik, S; Stephani, RA	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329851&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10076527	123108966		CHEMBL1204990				ZINC01490514	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725244	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C40H56N10O9/c1-6-22(4)34(38(56)48-31(40(58)59)15-24-18-43-27-11-8-7-10-26(24)27)49-37(55)32-12-9-13-50(32)39(57)30(17-33(41)52)47-35(53)28(14-21(2)3)46-36(54)29(45-23(5)51)16-25-19-42-20-44-25/h7-8,10-11,18-22,28-32,34,43H,6,9,12-17H2,1-5H3,(H2,41,52)(H,42,44)(H,45,51)(H,46,54)(H,47,53)(H,48,56)(H,49,55)(H,58,59)/t22-,28-,29+,30-,31-,32-,34-/m0/s1	IFIKNQQQCVILSJ-VVKPWJFGSA-N	50366417	CHEMBL2369712	Endothelin-1 receptor			>50000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366417&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73348424	160845519		CHEMBL2369712				ZINC95548213	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725246	CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26+,32-,33-,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-KIGKRTBVSA-N	50366422	CHEMBL1791272	Endothelin-1 receptor			 30000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366422&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56671553	160845524		CHEMBL1791272				ZINC95548665	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725250	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C39H57N9O9/c1-7-21(5)32(37(54)46-30(39(56)57)14-23-17-42-27-12-10-9-11-25(23)27)48-38(55)33(22(6)8-2)47-36(53)29(16-31(49)50)45-35(52)28(13-20(3)4)44-34(51)26(40)15-24-18-41-19-43-24/h9-12,17-22,26,28-30,32-33,42H,7-8,13-16,40H2,1-6H3,(H,41,43)(H,44,51)(H,45,52)(H,46,54)(H,47,53)(H,48,55)(H,49,50)(H,56,57)/t21-,22-,26-,28-,29-,30-,32-,33-/m0/s1	NTSBFTNRWQVBCA-IVGDYKFASA-N	50000565	(S)-3-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-((S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::3-{2-[2-Amino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL34540	Endothelin-1 receptor			>50000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000565&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			129432	103915113		CHEMBL34540				ZINC95611937	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725251	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30+,37-,38-,39-,42-,43-,44-/m0/s1	XUMJJSAQQCTKAO-HZVVOHTCSA-N	50366421	CHEMBL1791271	Endothelin-1 receptor			 14							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366421&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56668088	160845523		CHEMBL1791271					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725253	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H58N8O9/c1-6-25(4)37(41(57)49-34(43(59)60)21-28-23-45-30-16-11-10-15-29(28)30)50-40(56)35-17-12-18-51(35)42(58)33(22-36(44)53)48-38(54)31(19-24(2)3)47-39(55)32(46-26(5)52)20-27-13-8-7-9-14-27/h7-11,13-16,23-25,31-35,37,45H,6,12,17-22H2,1-5H3,(H2,44,53)(H,46,52)(H,47,55)(H,48,54)(H,49,57)(H,50,56)(H,59,60)/t25-,31-,32+,33-,34-,35-,37-/m0/s1	BWWOWLFWAYYUTP-YKMRINICSA-N	50366424	CHEMBL2369709	Endothelin-1 receptor			 40							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366424&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10033429	160845526		CHEMBL2369709				ZINC95548667	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725255	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H62N8O9/c1-6-29(4)42(46(62)55-38(49(65)66)25-33-27-51-35-21-14-13-20-34(33)35)56-45(61)39-22-15-23-57(39)48(64)37(26-40(50)59)54-44(60)36(24-28(2)3)53-47(63)43(52-30(5)58)41(31-16-9-7-10-17-31)32-18-11-8-12-19-32/h7-14,16-21,27-29,36-39,41-43,51H,6,15,22-26H2,1-5H3,(H2,50,59)(H,52,58)(H,53,63)(H,54,60)(H,55,62)(H,56,61)(H,65,66)/t29-,36-,37-,38-,39-,42-,43-/m0/s1	MNCHXABXDSNNQG-HCTUGONBSA-N	50366416	CHEMBL2369713	Endothelin-1 receptor			 3200							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366416&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73350002	160845518		CHEMBL2369713					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725256	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)[C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C39H53N9O12/c1-6-19(3)32(37(57)46-29(39(59)60)12-22-16-41-25-11-9-8-10-24(22)25)48-38(58)33(20(4)7-2)47-36(56)28(15-31(52)53)45-35(55)27(14-30(50)51)44-34(54)26(43-21(5)49)13-23-17-40-18-42-23/h8-11,16-20,26-29,32-33,41H,6-7,12-15H2,1-5H3,(H,40,42)(H,43,49)(H,44,54)(H,45,55)(H,46,57)(H,47,56)(H,48,58)(H,50,51)(H,52,53)(H,59,60)/t19-,20+,26-,27-,28-,29-,32-,33-/m0/s1	FFHBVWCUKLBZIM-ISNUVAIJSA-N	50366425	CHEMBL1791277	Endothelin-1 receptor			>25000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366425&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56671554	160845527		CHEMBL1791277				ZINC95548188	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725258	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C40H55N9O10/c1-6-22(4)34(38(56)47-31(40(58)59)15-24-18-42-27-11-8-7-10-26(24)27)48-37(55)32-12-9-13-49(32)39(57)30(17-33(51)52)46-35(53)28(14-21(2)3)45-36(54)29(44-23(5)50)16-25-19-41-20-43-25/h7-8,10-11,18-22,28-32,34,42H,6,9,12-17H2,1-5H3,(H,41,43)(H,44,50)(H,45,54)(H,46,53)(H,47,56)(H,48,55)(H,51,52)(H,58,59)/t22-,28-,29-,30-,31-,32-,34-/m0/s1	MKZHMDBHWUGCGW-WSLLFAHXSA-N	50366420	CHEMBL2369711	Endothelin-1 receptor			>50000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366420&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73351511	160845522		CHEMBL2369711			C00615	ZINC95548641	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725260	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H58N8O9/c1-6-25(4)37(41(57)49-34(43(59)60)21-28-23-45-30-16-11-10-15-29(28)30)50-40(56)35-17-12-18-51(35)42(58)33(22-36(44)53)48-38(54)31(19-24(2)3)47-39(55)32(46-26(5)52)20-27-13-8-7-9-14-27/h7-11,13-16,23-25,31-35,37,45H,6,12,17-22H2,1-5H3,(H2,44,53)(H,46,52)(H,47,55)(H,48,54)(H,49,57)(H,50,56)(H,59,60)/t25-,31-,32-,33-,34-,35-,37-/m0/s1	BWWOWLFWAYYUTP-SBRODVMZSA-N	50366419	CHEMBL2369710	Endothelin-1 receptor			 24000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366419&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73354491	160845521		CHEMBL2369710				ZINC95548639	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725261	CC[C@@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26+,32-,33+,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-JAMUSYCNSA-N	50366423	CHEMBL1791279	Endothelin-1 receptor			 1800							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366423&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56674998	160845525		CHEMBL1791279				ZINC95548193	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724610	CCCC[C@H](NC(=O)[C@@H](Cc1c([nH]c2ccccc12)C#N)NC(=O)C(NC(=O)N1[C@@H](C)CCC[C@H]1C)C(C)C)C(O)=O	InChI=1S/C31H44N6O5/c1-6-7-14-24(30(40)41)34-28(38)25(16-22-21-13-8-9-15-23(21)33-26(22)17-32)35-29(39)27(18(2)3)36-31(42)37-19(4)11-10-12-20(37)5/h8-9,13,15,18-20,24-25,27,33H,6-7,10-12,14,16H2,1-5H3,(H,34,38)(H,35,39)(H,36,42)(H,40,41)/t19-,20+,24-,25+,27?/m0/s1	WTIMYTIFDDIBIP-DBKYNLIOSA-N	50284768	(S)-2-((R)-3-(2-Cyano-1H-indol-3-yl)-2-{2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-3-methyl-butyrylamino}-propionylamino)-hexanoic acid::CHEMBL431124	Endothelin-1 receptor			 6100							ChEMBL	10.1016/0960-894X(95)00237-N	10.7270/Q27D2VM3				Fukami, T; Yamakawa, T; Kojima, H; Amano, Y; Ihara, M; Yano, M; Ishikawa, K	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284768	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284768&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44283270	104126339		CHEMBL431124				ZINC26398399	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724621	CCCC[C@H](NC(=O)[C@@H](Cc1c(Br)[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)N1[C@@H](C)CCC[C@H]1C)C1CC1)C(O)=O	InChI=1S/C30H42BrN5O5/c1-4-5-12-23(29(39)40)33-27(37)24(16-21-20-11-6-7-13-22(20)32-26(21)31)34-28(38)25(19-14-15-19)35-30(41)36-17(2)9-8-10-18(36)3/h6-7,11,13,17-19,23-25,32H,4-5,8-10,12,14-16H2,1-3H3,(H,33,37)(H,34,38)(H,35,41)(H,39,40)/t17-,18+,23-,24+,25-/m0/s1	XDNAXXIOBHFZDQ-PKWKGPSUSA-N	50284769	(S)-2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{(S)-2-cyclopropyl-2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-acetylamino}-propionylamino)-hexanoic acid::CHEMBL284250	Endothelin-1 receptor			 16							ChEMBL	10.1016/0960-894X(95)00237-N	10.7270/Q27D2VM3				Fukami, T; Yamakawa, T; Kojima, H; Amano, Y; Ihara, M; Yano, M; Ishikawa, K	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284769&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44283471	104126340		CHEMBL284250				ZINC26387521	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726406	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)-c1ncccn1	InChI=1S/C33H33N7O7S/c1-33(2,3)22-13-15-23(16-14-22)48(42,43)40-28-27(47-25-11-6-5-10-24(25)44-4)31(39-30(38-28)29-35-18-9-19-36-29)45-20-21-46-32(41)37-26-12-7-8-17-34-26/h5-19H,20-21H2,1-4H3,(H,34,37,41)(H,38,39,40)	RZTQQRCQEYQARM-UHFFFAOYSA-N	50290041	CHEMBL70203::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-ethyl ester	Endothelin-1 receptor			 6							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290041&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44212539	104131612		CHEMBL70203				ZINC03980528	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726409	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C31H35N7O8S/c1-21(2)22-11-12-26(33-20-22)47(40,41)37-28-27(46-24-9-5-4-8-23(24)42-3)29(36-30(35-28)38-14-16-43-17-15-38)44-18-19-45-31(39)34-25-10-6-7-13-32-25/h4-13,20-21H,14-19H2,1-3H3,(H,32,34,39)(H,35,36,37)	MXLGWPUNPPHJQC-UHFFFAOYSA-N	50290043	CHEMBL72037::Pyridin-2-yl-carbamic acid 2-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290043&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9809919	104131614		CHEMBL72037				ZINC03977732	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726413	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCO	InChI=1S/C24H29N3O6S/c1-16-25-22(27-34(29,30)18-12-10-17(11-13-18)24(2,3)4)21(23(26-16)32-15-14-28)33-20-9-7-6-8-19(20)31-5/h6-13,28H,14-15H2,1-5H3,(H,25,26,27)	QCPAJDRNULDARS-UHFFFAOYSA-N	50290045	4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL72473	Endothelin-1 receptor			 1500							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290045&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19432649	104131616		CHEMBL72473				ZINC26375471	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726416	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCOC(=O)c1cccnc1	InChI=1S/C30H32N4O7S/c1-20-32-27(34-42(36,37)23-14-12-22(13-15-23)30(2,3)4)26(41-25-11-7-6-10-24(25)38-5)28(33-20)39-17-18-40-29(35)21-9-8-16-31-19-21/h6-16,19H,17-18H2,1-5H3,(H,32,33,34)	NBEGSXJDADJYHX-UHFFFAOYSA-N	50290048	CHEMBL70781::Nicotinic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 880							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290048&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311288	104131619		CHEMBL70781				ZINC26289769	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726418	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)C(C)C	InChI=1S/C32H37N5O7S/c1-21(2)28-35-29(37-45(39,40)23-16-14-22(15-17-23)32(3,4)5)27(44-25-12-8-7-11-24(25)41-6)30(36-28)42-19-20-43-31(38)34-26-13-9-10-18-33-26/h7-18,21H,19-20H2,1-6H3,(H,33,34,38)(H,35,36,37)	PWHUJWODHSRAIM-UHFFFAOYSA-N	50290049	CHEMBL71070::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-2-isopropyl-5-(2-methoxy-phenoxy)-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 7							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290049&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311284	104131620		CHEMBL71070				ZINC26289754	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726419	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C29H31N7O8S/c1-20-10-11-24(31-19-20)45(38,39)35-26-25(44-22-8-4-3-7-21(22)40-2)27(34-28(33-26)36-13-15-41-16-14-36)42-17-18-43-29(37)32-23-9-5-6-12-30-23/h3-12,19H,13-18H2,1-2H3,(H,30,32,37)(H,33,34,35)	OOJYMKAJOJBARX-UHFFFAOYSA-N	50290050	CHEMBL70385::Pyridin-2-yl-carbamic acid 2-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 0.200000							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290050&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9939238	104131621		CHEMBL70385				ZINC03946721	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726420	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H]2CSSC[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C109H159N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80-49-169-168-48-64(111)89(145)126-77(45-135)102(158)131-81-50-170-171-51-82(105(161)132-86(55(7)8)106(162)124-72(38-59-26-28-62(138)29-27-59)95(151)120-71(96(152)130-80)37-58-21-15-14-16-22-58)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-167-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(81)160/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64+,66-,67-,68-,69+,70-,71-,72+,73-,74+,75-,76-,77+,78-,79+,80-,81-,82+,86-,87-,88-/m0/s1	ZUBDGKVDJUIMQQ-UBFCDGJISA-N	50000558	CHEMBL437472::ET-1::Endothelin -1::Endothelin 1, ET-1::Endothelin derivative::Endothelin-1::c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp-Lys-Gln-Cys)-Val-Tyr-Phe-Cys)-His-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor			 0.200000							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91928636	103915106		CHEMBL437472					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726422	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCOC(=O)c1ccoc1	InChI=1S/C29H31N3O8S/c1-19-30-26(32-41(34,35)22-12-10-21(11-13-22)29(2,3)4)25(40-24-9-7-6-8-23(24)36-5)27(31-19)38-16-17-39-28(33)20-14-15-37-18-20/h6-15,18H,16-17H2,1-5H3,(H,30,31,32)	DNVZRTCDKDRZAF-UHFFFAOYSA-N	50290052	CHEMBL74118::Furan-3-carboxylic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 1100							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290052&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311225	104131623		CHEMBL74118				ZINC26376068	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726423	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCSCC1	InChI=1S/C31H35N7O7S2/c1-21(2)22-11-12-26(33-20-22)47(40,41)37-28-27(45-24-9-5-4-8-23(24)42-3)29(36-30(35-28)38-14-18-46-19-15-38)43-16-17-44-31(39)34-25-10-6-7-13-32-25/h4-13,20-21H,14-19H2,1-3H3,(H,32,34,39)(H,35,36,37)	FCGUSVKFZTVUQB-UHFFFAOYSA-N	50290047	CHEMBL308088::Pyridin-2-yl-carbamic acid 2-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-thiomorpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 1							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290047&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311346	104131618		CHEMBL308088				ZINC26291435	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726424	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C33H38N6O8S/c1-33(2,3)23-12-14-24(15-13-23)48(41,42)38-29-28(47-26-10-6-5-9-25(26)43-4)30(37-31(36-29)39-17-19-44-20-18-39)45-21-22-46-32(40)35-27-11-7-8-16-34-27/h5-16H,17-22H2,1-4H3,(H,34,35,40)(H,36,37,38)	HOULTIREPNOFQE-UHFFFAOYSA-N	50290053	CHEMBL70339::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 17							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290053&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311516	104131624		CHEMBL70339				ZINC26295311	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726428	CNCC(=O)OCCOc1nc(C)nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1Oc1ccccc1OC	InChI=1S/C27H34N4O7S/c1-18-29-25(31-39(33,34)20-13-11-19(12-14-20)27(2,3)4)24(38-22-10-8-7-9-21(22)35-6)26(30-18)37-16-15-36-23(32)17-28-5/h7-14,28H,15-17H2,1-6H3,(H,29,30,31)	VAYHZKZVSIYORZ-UHFFFAOYSA-N	50290054	CHEMBL435895::Methylamino-acetic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 1700							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290054&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44387128	104131625		CHEMBL435895				ZINC28105722	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726430	CCCc1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OCCOC(=O)Nc2ccccn2)n1	InChI=1S/C32H37N5O7S/c1-6-11-27-34-29(37-45(39,40)23-17-15-22(16-18-23)32(2,3)4)28(44-25-13-8-7-12-24(25)41-5)30(35-27)42-20-21-43-31(38)36-26-14-9-10-19-33-26/h7-10,12-19H,6,11,20-21H2,1-5H3,(H,33,36,38)(H,34,35,37)	ZYPQETRCACBJNS-UHFFFAOYSA-N	50290055	CHEMBL303428::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-propyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 9							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290055&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311285	104131626		CHEMBL303428				ZINC26289759	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726431	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)C1CC1	InChI=1S/C32H35N5O7S/c1-32(2,3)22-14-16-23(17-15-22)45(39,40)37-29-27(44-25-10-6-5-9-24(25)41-4)30(36-28(35-29)21-12-13-21)42-19-20-43-31(38)34-26-11-7-8-18-33-26/h5-11,14-18,21H,12-13,19-20H2,1-4H3,(H,33,34,38)(H,35,36,37)	JOZGLYQYYYGZBS-UHFFFAOYSA-N	50290042	CHEMBL70487::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-2-cyclopropyl-5-(2-methoxy-phenoxy)-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 7							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290042&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311528	104131613		CHEMBL70487				ZINC26293084	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726432	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCOC(=O)Nc1ccncc1	InChI=1S/C30H33N5O7S/c1-20-32-27(35-43(37,38)23-12-10-21(11-13-23)30(2,3)4)26(42-25-9-7-6-8-24(25)39-5)28(33-20)40-18-19-41-29(36)34-22-14-16-31-17-15-22/h6-17H,18-19H2,1-5H3,(H,31,34,36)(H,32,33,35)	OGZPTMZDUNEWQZ-UHFFFAOYSA-N	50290056	CHEMBL307803::Pyridin-4-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 1900							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290056&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311218	104131627		CHEMBL307803				ZINC26295737	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726433	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCOC(=O)Nc1ccccn1)-c1ncccn1	InChI=1S/C29H26N8O7S/c1-19-11-12-23(33-18-19)45(39,40)37-25-24(44-21-9-4-3-8-20(21)41-2)28(36-27(35-25)26-31-14-7-15-32-26)42-16-17-43-29(38)34-22-10-5-6-13-30-22/h3-15,18H,16-17H2,1-2H3,(H,30,34,38)(H,35,36,37)	YDIGUOCUKLHGNZ-UHFFFAOYSA-N	50290057	CHEMBL70303::Pyridin-2-yl-carbamic acid 2-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-[2,2']bipyrimidinyl-4-yloxy]-ethyl ester	Endothelin-1 receptor			 4							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290057	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290057&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311233	104131628		CHEMBL70303				ZINC26289674	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726438	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)C(C)(C)C	InChI=1S/C33H39N5O7S/c1-32(2,3)22-15-17-23(18-16-22)46(40,41)38-28-27(45-25-13-9-8-12-24(25)42-7)29(37-30(36-28)33(4,5)6)43-20-21-44-31(39)35-26-14-10-11-19-34-26/h8-19H,20-21H2,1-7H3,(H,34,35,39)(H,36,37,38)	XPOWMKNHKCJZNA-UHFFFAOYSA-N	50290051	CHEMBL303649::Pyridin-2-yl-carbamic acid 2-[2-tert-butyl-6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 14							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290051&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311283	104131622		CHEMBL303649				ZINC26291122	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726439	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCNC(=O)Nc1ccccn1	InChI=1S/C30H34N6O6S/c1-20-33-27(36-43(38,39)22-15-13-21(14-16-22)30(2,3)4)26(42-24-11-7-6-10-23(24)40-5)28(34-20)41-19-18-32-29(37)35-25-12-8-9-17-31-25/h6-17H,18-19H2,1-5H3,(H,33,34,36)(H2,31,32,35,37)	AHRRXSCSEHTVQL-UHFFFAOYSA-N	50290058	4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-methyl-6-[2-(3-pyridin-2-yl-ureido)-ethoxy]-pyrimidin-4-yl}-benzenesulfonamide::CHEMBL70924	Endothelin-1 receptor			 80							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290058&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19432672	104131629		CHEMBL70924				ZINC26289649	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726442	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)C1CCNCC1	InChI=1S/C32H37N7O7S/c1-21(2)23-11-12-27(35-20-23)47(41,42)39-30-28(46-25-9-5-4-8-24(25)43-3)31(38-29(37-30)22-13-16-33-17-14-22)44-18-19-45-32(40)36-26-10-6-7-15-34-26/h4-12,15,20-22,33H,13-14,16-19H2,1-3H3,(H,34,36,40)(H,37,38,39)	KXJZFAQLRGGYSV-UHFFFAOYSA-N	50290059	CHEMBL70895::Pyridin-2-yl-carbamic acid 2-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-piperidin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 3							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290059&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311345	104131630		CHEMBL70895				ZINC26291019	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726447	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCOC(=O)Nc1ccccn1	InChI=1S/C30H33N5O7S/c1-20-32-27(35-43(37,38)22-15-13-21(14-16-22)30(2,3)4)26(42-24-11-7-6-10-23(24)39-5)28(33-20)40-18-19-41-29(36)34-25-12-8-9-17-31-25/h6-17H,18-19H2,1-5H3,(H,31,34,36)(H,32,33,35)	NNLKMQXTQXTMET-UHFFFAOYSA-N	50290044	CHEMBL70800::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 6							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290044&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311135	104131615		CHEMBL70800				ZINC26294287	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006863	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H]2CSSC[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C109H159N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80-49-169-168-48-64(111)89(145)126-77(45-135)102(158)131-81-50-170-171-51-82(105(161)132-86(55(7)8)106(162)124-72(38-59-26-28-62(138)29-27-59)95(151)120-71(96(152)130-80)37-58-21-15-14-16-22-58)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-167-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(81)160/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64+,66-,67-,68-,69+,70-,71-,72+,73-,74+,75-,76-,77+,78-,79+,80-,81-,82+,86-,87-,88-/m0/s1	ZUBDGKVDJUIMQQ-UBFCDGJISA-N	50000558	CHEMBL437472::ET-1::Endothelin -1::Endothelin 1, ET-1::Endothelin derivative::Endothelin-1::c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp-Lys-Gln-Cys)-Val-Tyr-Phe-Cys)-His-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91928636	103915106		CHEMBL437472					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726450	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)-c1cccs1	InChI=1S/C33H33N5O7S2/c1-33(2,3)22-14-16-23(17-15-22)47(40,41)38-30-28(45-25-11-6-5-10-24(25)42-4)31(37-29(36-30)26-12-9-21-46-26)43-19-20-44-32(39)35-27-13-7-8-18-34-27/h5-18,21H,19-20H2,1-4H3,(H,34,35,39)(H,36,37,38)	VVOGFCYZFAKNMH-UHFFFAOYSA-N	50290061	CHEMBL70365::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-thiophen-2-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 30							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290061&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311527	104131632		CHEMBL70365				ZINC26293079	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726451	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)-c1ncccn1	InChI=1S/C31H30N8O7S/c1-20(2)21-12-13-25(35-19-21)47(41,42)39-27-26(46-23-10-5-4-9-22(23)43-3)30(38-29(37-27)28-33-15-8-16-34-28)44-17-18-45-31(40)36-24-11-6-7-14-32-24/h4-16,19-20H,17-18H2,1-3H3,(H,32,36,40)(H,37,38,39)	QGSBCBLFBNGHAE-UHFFFAOYSA-N	50290060	CHEMBL70293::Pyridin-2-yl-carbamic acid 2-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-ethyl ester	Endothelin-1 receptor			 4							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290060&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311232	104131631		CHEMBL70293				ZINC26291059	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50726452	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(C)nc1OCCOC(=O)Nc1cccnc1	InChI=1S/C30H33N5O7S/c1-20-32-27(35-43(37,38)23-14-12-21(13-15-23)30(2,3)4)26(42-25-11-7-6-10-24(25)39-5)28(33-20)40-17-18-41-29(36)34-22-9-8-16-31-19-22/h6-16,19H,17-18H2,1-5H3,(H,34,36)(H,32,33,35)	GINOPQFPTRYBHX-UHFFFAOYSA-N	50290046	CHEMBL70788::Pyridin-3-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 900							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290046&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44311321	104131617		CHEMBL70788				ZINC26295375	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724977	CCCN1c2ccc(NC(=O)Cc3c[nH]c4ccccc34)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C28H26N4O4/c1-2-13-31-23-10-6-4-8-21(23)28(36)32(17-27(34)35)25-15-19(11-12-24(25)31)30-26(33)14-18-16-29-22-9-5-3-7-20(18)22/h3-12,15-16,29H,2,13-14,17H2,1H3,(H,30,33)(H,34,35)	BOLITTSKJVCYEH-UHFFFAOYSA-N	50286234	CHEMBL86489::[8-(2-1H-Indol-3-yl-acetylamino)-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl]-acetic acid	Endothelin-1 receptor		 14000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286234&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19934544	104127805		CHEMBL86489				ZINC00592765	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724978	CCCN1c2ccc(Cc3c[nH]c4ccccc34)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C27H25N3O3/c1-2-13-29-23-10-6-4-8-21(23)27(33)30(17-26(31)32)25-15-18(11-12-24(25)29)14-19-16-28-22-9-5-3-7-20(19)22/h3-12,15-16,28H,2,13-14,17H2,1H3,(H,31,32)	IVZAYUAZBDJOED-UHFFFAOYSA-N	50286235	CHEMBL313184::[8-(1H-Indol-3-ylmethyl)-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl]-acetic acid	Endothelin-1 receptor		 41000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19934549	104127806		CHEMBL313184				ZINC00592763	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724979	CCCN1c2ccc(NC(=O)c3cccc4ccccc34)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C29H25N3O4/c1-2-16-31-24-13-6-5-11-23(24)29(36)32(18-27(33)34)26-17-20(14-15-25(26)31)30-28(35)22-12-7-9-19-8-3-4-10-21(19)22/h3-15,17H,2,16,18H2,1H3,(H,30,35)(H,33,34)	ANAZUOVTIBXIDF-UHFFFAOYSA-N	50286236	CHEMBL316247::{8-[(Naphthalene-1-carbonyl)-amino]-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl}-acetic acid	Endothelin-1 receptor		 83000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286236	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286236&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320537	104127807		CHEMBL316247				ZINC26575754	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724983	CCCN1c2ccc(OCc3cccc4ccccc34)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C29H26N2O4/c1-2-16-30-25-13-6-5-12-24(25)29(34)31(18-28(32)33)27-17-22(14-15-26(27)30)35-19-21-10-7-9-20-8-3-4-11-23(20)21/h3-15,17H,2,16,18-19H2,1H3,(H,32,33)	UOTQQUOXKAFPCO-UHFFFAOYSA-N	50286237	CHEMBL86581::[8-(Naphthalen-1-ylmethoxy)-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl]-acetic acid	Endothelin-1 receptor		 7000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286237&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19934546	104127808		CHEMBL86581				ZINC01542051	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724984	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc2cccc3ccccc23)NC1=O)C(C)C	InChI=1S/C33H43N5O7/c1-18(2)15-23-29(41)34-24(16-21-11-7-10-20-9-5-6-12-22(20)21)30(42)36-25(17-27(39)40)33(45)38-14-8-13-26(38)31(43)37-28(19(3)4)32(44)35-23/h5-7,9-12,18-19,23-26,28H,8,13-17H2,1-4H3,(H,34,41)(H,35,44)(H,36,42)(H,37,43)(H,39,40)/t23-,24+,25+,26-,28+/m0/s1	VIKVVYZEMQCXCA-BKVOUIBNSA-N	50286239	CHEMBL315927::[(1S,4R,5R)-11-((S)-Isobutyl)-14-((R)-isopropyl)-8-naphthalen-1-ylmethyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor		 224								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286239&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320243	104127810		CHEMBL315927				ZINC26575548	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724985	CCCN1c2ccc(NCc3cccc4ccccc34)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C29H27N3O3/c1-2-16-31-25-13-6-5-12-24(25)29(35)32(19-28(33)34)27-17-22(14-15-26(27)31)30-18-21-10-7-9-20-8-3-4-11-23(20)21/h3-15,17,30H,2,16,18-19H2,1H3,(H,33,34)	SFJAHCMIICUNGP-UHFFFAOYSA-N	50286240	CHEMBL314915::{8-[(Naphthalen-1-ylmethyl)-amino]-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl}-acetic acid	Endothelin-1 receptor		 17000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286240&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9934204	104127811		CHEMBL314915				ZINC01542052	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724988	CCCN1c2ccc(NC(=O)c3c[nH]c4ccccc34)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C27H24N4O4/c1-2-13-30-22-10-6-4-8-19(22)27(35)31(16-25(32)33)24-14-17(11-12-23(24)30)29-26(34)20-15-28-21-9-5-3-7-18(20)21/h3-12,14-15,28H,2,13,16H2,1H3,(H,29,34)(H,32,33)	YASYIXCWWXAKAQ-UHFFFAOYSA-N	50286242	CHEMBL315096::{8-[(1H-Indole-3-carbonyl)-amino]-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl}-acetic acid	Endothelin-1 receptor		 80000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286242&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19934535	104127813		CHEMBL315096				ZINC01484703	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724989	OC(=O)CN1c2cc(OCc3cccc4ccccc34)ccc2Nc2ccccc2C1=O	InChI=1S/C26H20N2O4/c29-25(30)15-28-24-14-19(32-16-18-8-5-7-17-6-1-2-9-20(17)18)12-13-23(24)27-22-11-4-3-10-21(22)26(28)31/h1-14,27H,15-16H2,(H,29,30)	QJEJIWLCLJPSNP-UHFFFAOYSA-N	50286243	CHEMBL421349::[8-(Naphthalen-1-ylmethoxy)-11-oxo-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl]-acetic acid	Endothelin-1 receptor		 28000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286243&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297287	104127814		CHEMBL421349				ZINC00592761	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724991	OC(=O)CN1c2cc(OCc3ccccc3)ccc2Nc2ccccc2C1=O	InChI=1S/C22H18N2O4/c25-21(26)13-24-20-12-16(28-14-15-6-2-1-3-7-15)10-11-19(20)23-18-9-5-4-8-17(18)22(24)27/h1-12,23H,13-14H2,(H,25,26)	YTAKRFVKWAPNOF-UHFFFAOYSA-N	50286241	(8-Benzyloxy-11-oxo-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl)-acetic acid::CHEMBL87859	Endothelin-1 receptor		 109000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286241&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19934540	104127812		CHEMBL87859				ZINC00592762	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724994	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23-,24-,26+/m0/s1	VYCMAAOURFJIHD-AOYLRGCGSA-N	50329850	(R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indol-3-ylmethyl)-2-oxo-ethylcarbamoyl]-3-methyl-but-3-enylcarbamoyl}-2-methyl-propylcarbamoyl)-pyrrolidin-1-yl]-4-oxo-butyric acid::2-((3R,6S,9R,12S,17aS)-9-((1H-indol-3-yl)methyl)-6-isobutyl-3-isopropyl-1,4,7,10,13-pentaoxohexadecahydro-1H-pyrrolo[1,2-a][1,4,7,10,13]pentaazacyclopentadecin-12-yl)acetic acid::CHEMBL1269102::[(1S,4R,5R)-8-(1H-Indol-3-ylmethyl)-11-((S)-isobutyl)-14-((R)-isopropyl)-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid::[(5R,8R,11S,14R,16aR)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid::[(5R,8R,11S,14R,16aS)-8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid::[8-(1H-Indol-3-ylmethyl)-11-isobutyl-14-isopropyl-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor		 18								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329850&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943236	123108965		CHEMBL1269102				ZINC60291636	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724995	CCCN1c2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2N(CC(O)=O)C(=O)c2ccccc12	InChI=1S/C27H24N4O4/c1-2-13-30-22-10-6-4-8-19(22)27(35)31(16-25(32)33)24-15-18(11-12-23(24)30)28-26(34)21-14-17-7-3-5-9-20(17)29-21/h3-12,14-15,29H,2,13,16H2,1H3,(H,28,34)(H,32,33)	UPABGOZTDGNXSU-UHFFFAOYSA-N	50286238	CHEMBL314364::{8-[(1H-Indole-2-carbonyl)-amino]-11-oxo-5-propyl-5,11-dihydro-dibenzo[b,e][1,4]diazepin-10-yl}-acetic acid	Endothelin-1 receptor		 33000								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286238&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19934534	104127809		CHEMBL314364				ZINC01484704	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50724996	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(C)C	InChI=1S/C29H41N5O7/c1-16(2)13-19-25(37)30-20(14-18-9-6-5-7-10-18)26(38)32-21(15-23(35)36)29(41)34-12-8-11-22(34)27(39)33-24(17(3)4)28(40)31-19/h5-7,9-10,16-17,19-22,24H,8,11-15H2,1-4H3,(H,30,37)(H,31,40)(H,32,38)(H,33,39)(H,35,36)/t19-,20+,21+,22-,24+/m0/s1	ZNQOPZHWWHVGAE-KVZQYWQLSA-N	50286244	CHEMBL87296::[(1S,4R,5R)-8-Benzyl-11-((S)-isobutyl)-14-((R)-isopropyl)-4,7,10,13,16-pentaoxo-hexadecahydro-3a,6,9,12,15-pentaaza-cyclopentacyclopentadecen-5-yl]-acetic acid	Endothelin-1 receptor		 2400								ChEMBL	10.1016/0960-894X(95)00019-P	10.7270/Q2X067JB				Murugesan, N; Zhengxiang, Gu; Lee, V; Webb, ML; Liu, EC; Hermsmeier, M; Hunt, JT	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286244&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10793187	104127815		CHEMBL87296				ZINC26576218	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725235	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30+,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-DZZYDSNESA-N	50000566	(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-((S)-1-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::(S)-3-{(S)-2-[(R)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL289687	Endothelin-1 receptor			 8900							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000566&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284284	103915114		CHEMBL289687				ZINC95607973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725236	CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H60N10O9/c1-8-22(5)34(39(57)49-32(41(59)60)15-25-18-44-28-13-11-10-12-27(25)28)51-40(58)35(23(6)9-2)50-38(56)31(17-33(42)53)48-36(54)29(14-21(3)4)47-37(55)30(46-24(7)52)16-26-19-43-20-45-26/h10-13,18-23,29-32,34-35,44H,8-9,14-17H2,1-7H3,(H2,42,53)(H,43,45)(H,46,52)(H,47,55)(H,48,54)(H,49,57)(H,50,56)(H,51,58)(H,59,60)/t22-,23-,29-,30-,31-,32-,34-,35-/m0/s1	HIMUEQQIDWTVOU-CXDMSSIXSA-N	50366415	CHEMBL1791280	Endothelin-1 receptor			 13000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366415&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56661220	160845517		CHEMBL1791280				ZINC95548211	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725239	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30-,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-CXDMSSIXSA-N	50000553	(S)-3-{(S)-2-[(S)-2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::Ac-His-Leu-Asp-Ile-Ile-D-Trp::CHEMBL432091	Endothelin-1 receptor			>50000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000553&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284385	103915101		CHEMBL432091				ZINC95614744	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50725240	CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C40H56N10O9/c1-6-22(4)34(38(56)48-31(40(58)59)15-24-18-43-27-11-8-7-10-26(24)27)49-37(55)32-12-9-13-50(32)39(57)30(17-33(41)52)47-35(53)28(14-21(2)3)46-36(54)29(45-23(5)51)16-25-19-42-20-44-25/h7-8,10-11,18-22,28-32,34,43H,6,9,12-17H2,1-5H3,(H2,41,52)(H,42,44)(H,45,51)(H,46,54)(H,47,53)(H,48,56)(H,49,55)(H,58,59)/t22-,28-,29-,30-,31-,32-,34-/m0/s1	IFIKNQQQCVILSJ-WSLLFAHXSA-N	50366418	CHEMBL2369714	Endothelin-1 receptor			>50000							ChEMBL	10.1016/0960-894X(95)00152-J	10.7270/Q2MG7PZH				Leonard, DM; Reily, MD; Dunbar, JB; Holub, KE; Cody, WL; Hill, KE; Welch, KM; Flynn, MA; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366418&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73352983	160845520		CHEMBL2369714			C00615	ZINC95548643	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760706	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30-,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-CXDMSSIXSA-N	50001214	3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL432091	Endothelin-1 receptor			>50000							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001214&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284385	103915679		CHEMBL432091			C00615	ZINC95614333	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760708	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C39H57N9O9/c1-7-21(5)32(37(54)46-30(39(56)57)14-23-17-42-27-12-10-9-11-25(23)27)48-38(55)33(22(6)8-2)47-36(53)29(16-31(49)50)45-35(52)28(13-20(3)4)44-34(51)26(40)15-24-18-41-19-43-24/h9-12,17-22,26,28-30,32-33,42H,7-8,13-16,40H2,1-6H3,(H,41,43)(H,44,51)(H,45,52)(H,46,54)(H,47,53)(H,48,55)(H,49,50)(H,56,57)/t21-,22-,26-,28-,29-,30-,32-,33-/m0/s1	NTSBFTNRWQVBCA-IVGDYKFASA-N	50001216	3-{2-[2-Amino-3-(1H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL34540	Endothelin-1 receptor			>50000							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001216&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			129432	103915681		CHEMBL34540				ZINC95546468	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760711	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H]2CSSC[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C109H159N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80-49-169-168-48-64(111)89(145)126-77(45-135)102(158)131-81-50-170-171-51-82(105(161)132-86(55(7)8)106(162)124-72(38-59-26-28-62(138)29-27-59)95(151)120-71(96(152)130-80)37-58-21-15-14-16-22-58)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-167-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(81)160/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64+,66-,67-,68-,69+,70-,71-,72+,73-,74+,75-,76-,77+,78-,79+,80-,81-,82+,86-,87-,88-/m0/s1	ZUBDGKVDJUIMQQ-UBFCDGJISA-N	50000558	CHEMBL437472::ET-1::Endothelin -1::Endothelin 1, ET-1::Endothelin derivative::Endothelin-1::c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp-Lys-Gln-Cys)-Val-Tyr-Phe-Cys)-His-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor			 0.200000							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91928636	103915106		CHEMBL437472					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760712	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33+,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-YNIJNJSISA-N	50001217	3-[2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL86814	Endothelin-1 receptor			 2800							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001217&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297023	103915682		CHEMBL86814				ZINC95610946	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760715	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O11/c1-8-24(5)37(42(59)49-35(44(61)62)20-28-22-45-31-13-11-10-12-30(28)31)51-43(60)38(25(6)9-2)50-41(58)34(21-36(54)55)48-39(56)32(18-23(3)4)47-40(57)33(46-26(7)52)19-27-14-16-29(53)17-15-27/h10-17,22-25,32-35,37-38,45,53H,8-9,18-21H2,1-7H3,(H,46,52)(H,47,57)(H,48,56)(H,49,59)(H,50,58)(H,51,60)(H,54,55)(H,61,62)/t24-,25-,32-,33+,34-,35-,37-,38-/m0/s1	KGENNXUISWGQKL-ZDRDUBIJSA-N	50001219	3-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL85341	Endothelin-1 receptor			 400							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001219&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321030	103915684		CHEMBL85341					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760718	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C46H62N8O10/c1-8-25(5)39(44(61)52-37(46(63)64)20-29-23-48-33-17-13-11-15-31(29)33)54-45(62)40(26(6)9-2)53-43(60)36(21-38(56)57)51-41(58)34(18-24(3)4)50-42(59)35(49-27(7)55)19-28-22-47-32-16-12-10-14-30(28)32/h10-17,22-26,34-37,39-40,47-48H,8-9,18-21H2,1-7H3,(H,49,55)(H,50,59)(H,51,58)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t25-,26-,34-,35+,36-,37-,39-,40-/m0/s1	ZYNCQGUPXUKGPO-CCAWOAKWSA-N	50001220	3-{2-[2-Acetylamino-3-(1H-indol-3-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL317064	Endothelin-1 receptor			 130							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001220&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9897583	103915685		CHEMBL317064					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760719	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1c[nH]cn1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H59N9O10/c1-8-22(5)34(39(57)48-32(41(59)60)15-25-18-43-28-13-11-10-12-27(25)28)50-40(58)35(23(6)9-2)49-38(56)31(17-33(52)53)47-36(54)29(14-21(3)4)46-37(55)30(45-24(7)51)16-26-19-42-20-44-26/h10-13,18-23,29-32,34-35,43H,8-9,14-17H2,1-7H3,(H,42,44)(H,45,51)(H,46,55)(H,47,54)(H,48,57)(H,49,56)(H,50,58)(H,52,53)(H,59,60)/t22-,23-,29-,30+,31-,32-,34-,35-/m0/s1	NGCFKFBXSAWULW-DZZYDSNESA-N	50001215	3-{2-[2-Acetylamino-3-(3H-imidazol-4-yl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL289687	Endothelin-1 receptor			 9500							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001215&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284284	103915680		CHEMBL289687				ZINC95546486	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760721	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)43(48(64)55-41(50(66)67)25-35-27-51-37-18-14-13-17-36(35)37)57-49(65)44(30(6)9-2)56-47(63)40(26-42(59)60)54-45(61)38(23-28(3)4)53-46(62)39(52-31(7)58)24-32-19-21-34(22-20-32)33-15-11-10-12-16-33/h10-22,27-30,38-41,43-44,51H,8-9,23-26H2,1-7H3,(H,52,58)(H,53,62)(H,54,61)(H,55,64)(H,56,63)(H,57,65)(H,59,60)(H,66,67)/t29-,30-,38-,39+,40-,41-,43-,44-/m0/s1	IFDNLSRYZKUGIR-KXXXQFFTSA-N	50001218	3-[2-(2-Acetylamino-3-biphenyl-4-yl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL438194	Endothelin-1 receptor			 4400							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001218&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122149	103915683		CHEMBL438194					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760722	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30-,37-,38-,39-,42-,43-,44-/m0/s1	XUMJJSAQQCTKAO-SRYIDKSASA-N	50032172	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL328942	Endothelin-1 receptor			 15							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032172&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9897720	103940722		CHEMBL328942					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50760723	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C48H63N7O10/c1-8-27(5)41(46(62)53-39(48(64)65)23-33-25-49-35-17-13-12-16-34(33)35)55-47(63)42(28(6)9-2)54-45(61)38(24-40(57)58)52-43(59)36(20-26(3)4)51-44(60)37(50-29(7)56)22-30-18-19-31-14-10-11-15-32(31)21-30/h10-19,21,25-28,36-39,41-42,49H,8-9,20,22-24H2,1-7H3,(H,50,56)(H,51,60)(H,52,59)(H,53,62)(H,54,61)(H,55,63)(H,57,58)(H,64,65)/t27-,28-,36-,37+,38-,39-,41-,42-/m0/s1	JSGRPPGXQMIRRM-MKZJQENTSA-N	50001221	3-[2-(2-Acetylamino-3-naphthalen-2-yl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL315047	Endothelin-1 receptor			 1000							ChEMBL	10.1021/jm00095a029	10.7270/Q21C1XGJ	1324321			Cody, WL; Doherty, AM; He, JX; DePue, PL; Rapundalo, ST; Hingorani, GA; Major, TC; Panek, RL; Dudley, DT; Haleen, SJ	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001221&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297025	103915686		CHEMBL315047					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781519	CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1	InChI=1S/C51H68N8O9/c1-8-30(5)44(59-51(68)45(31(6)9-2)58-47(64)37(52)25-35-27-53-38-23-17-16-22-36(35)38)50(67)57-40(26-42(62)63)49(66)56-39(24-29(3)4)48(65)54-28-41(61)46(55-32(7)60)43(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,27,29-31,37,39-40,43-46,53H,8-9,24-26,28,52H2,1-7H3,(H,54,65)(H,55,60)(H,56,66)(H,57,67)(H,58,64)(H,59,68)(H,62,63)/t30-,31+,37+,39+,40-,44-,45+,46-/m1/s1	OBEBMOZTYJHEGE-SPHUHDBCSA-N	50369263	CHEMBL1793924	Endothelin-1 receptor			 2700							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56681797	160848365		CHEMBL1793924					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781522	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30-,37-,38-,39-,42-,43-,44-/m0/s1	XUMJJSAQQCTKAO-SRYIDKSASA-N	50032172	(S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propionylamino)-4-methyl-pentanoylamino]-N-((1S,2S)-1-{(1S,2S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL328942	Endothelin-1 receptor			 58							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032172&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9897720	103940722		CHEMBL328942					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781524	CC[C@H](C)[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1	InChI=1S/C51H68N8O9/c1-8-30(5)44(59-50(67)45(31(6)9-2)58-47(64)37(52)25-35-27-53-38-23-17-16-22-36(35)38)49(66)57-40(26-42(62)63)48(65)54-28-41(61)39(24-29(3)4)56-51(68)46(55-32(7)60)43(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,27,29-31,37,39-40,43-46,53H,8-9,24-26,28,52H2,1-7H3,(H,54,65)(H,55,60)(H,56,68)(H,57,66)(H,58,64)(H,59,67)(H,62,63)/t30-,31-,37-,39-,40-,44-,45-,46-/m0/s1	FZNPXBBDYXQYLN-KFYDKIFBSA-N	50369266	CHEMBL1793925	Endothelin-1 receptor			 260							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56657875	160848368		CHEMBL1793925					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781525	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N(C)[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-9-30(5)43(50(66)58(8)45(31(6)10-2)49(65)56-40(51(67)68)26-35-28-52-37-24-18-17-23-36(35)37)57-47(63)39(27-41(60)61)54-46(62)38(25-29(3)4)55-48(64)44(53-32(7)59)42(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,28-31,38-40,42-45,52H,9-10,25-27H2,1-8H3,(H,53,59)(H,54,62)(H,55,64)(H,56,65)(H,57,63)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	YDAXRUPDVTYDII-KUIIPSLPSA-N	50369267	CHEMBL2369736	Endothelin-1 receptor			 80.0							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73348425	160848369		CHEMBL2369736					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781527	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)CC)C(=O)NCC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1	InChI=1S/C51H68N8O9/c1-8-30(5)44(59-50(67)45(31(6)9-2)58-47(64)37(52)25-35-27-53-38-23-17-16-22-36(35)38)49(66)54-28-41(61)39(26-42(62)63)56-48(65)40(24-29(3)4)57-51(68)46(55-32(7)60)43(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,27,29-31,37,39-40,43-46,53H,8-9,24-26,28,52H2,1-7H3,(H,54,66)(H,55,60)(H,56,65)(H,57,68)(H,58,64)(H,59,67)(H,62,63)/t30-,31-,37-,39-,40-,44-,45-,46-/m0/s1	YHLPUFACGFCANE-KFYDKIFBSA-N	50369269	CHEMBL1793932	Endothelin-1 receptor			 250							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369269&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56671734	160848371		CHEMBL1793932					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781529	CC[C@H](C)[C@H](NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-9-30(5)43(47(63)56-40(51(67)68)26-35-28-52-37-24-18-17-23-36(35)37)57-49(65)45(31(6)10-2)58(8)50(66)39(27-41(60)61)55-46(62)38(25-29(3)4)54-48(64)44(53-32(7)59)42(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,28-31,38-40,42-45,52H,9-10,25-27H2,1-8H3,(H,53,59)(H,54,64)(H,55,62)(H,56,63)(H,57,65)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	ZLLZUVCWXGJJGJ-KUIIPSLPSA-N	50369270	CHEMBL1793933	Endothelin-1 receptor			 700							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369270&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56668269	160848372		CHEMBL1793933					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781532	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-9-30(5)43(48(64)55-39(51(67)68)26-35-28-52-37-24-18-17-23-36(35)37)57-49(65)44(31(6)10-2)56-46(62)38(27-41(60)61)54-47(63)40(25-29(3)4)58(8)50(66)45(53-32(7)59)42(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,28-31,38-40,42-45,52H,9-10,25-27H2,1-8H3,(H,53,59)(H,54,63)(H,55,64)(H,56,62)(H,57,65)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	GKTACTKOCSBPJR-KUIIPSLPSA-N	50369273	CHEMBL1793926	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369273&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56668268	160848375		CHEMBL1793926					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781534	CC[C@H](C)[C@H](NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C1c2ccccc2CCc2ccccc12)C(=O)N(C)[C@H]([C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C53H69N7O10/c1-9-30(5)45(52(68)60(8)47(31(6)10-2)51(67)58-42(53(69)70)26-35-28-54-39-22-16-15-19-36(35)39)59-49(65)41(27-43(62)63)56-48(64)40(25-29(3)4)57-50(66)46(55-32(7)61)44-37-20-13-11-17-33(37)23-24-34-18-12-14-21-38(34)44/h11-22,28-31,40-42,44-47,54H,9-10,23-27H2,1-8H3,(H,55,61)(H,56,64)(H,57,66)(H,58,67)(H,59,65)(H,62,63)(H,69,70)/t30-,31+,40-,41+,42-,45-,46+,47+/m0/s1	IMUGSKXBYQZCBP-PXULEDTRSA-N	50369268	CHEMBL1790519	Endothelin-1 receptor			 1							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369268&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56679082	160848370		CHEMBL1790519					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50776218	CSCCC(NC(=O)[C@@H](Cc1c(C)[nH]c2ccccc12)NC(=O)C(NC(=O)N1[C@@H](C)CCC[C@H]1C)C1CC1)C(O)=O	InChI=1S/C30H43N5O5S/c1-17-8-7-9-18(2)35(17)30(40)34-26(20-12-13-20)28(37)33-25(27(36)32-24(29(38)39)14-15-41-4)16-22-19(3)31-23-11-6-5-10-21(22)23/h5-6,10-11,17-18,20,24-26,31H,7-9,12-16H2,1-4H3,(H,32,36)(H,33,37)(H,34,40)(H,38,39)/t17-,18+,24?,25-,26?/m1/s1	XUXCOWLSMHJSSY-OTQGITMZSA-N	50051394	2-[(R)-2-{2-Cyclopropyl-2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-acetylamino}-3-(2-methyl-1H-indol-3-yl)-propionylamino]-4-methylsulfanyl-butyric acid::CHEMBL307936	Endothelin-1 receptor			 3							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051394&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314904	103948392		CHEMBL307936				ZINC26400123	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50776220	CCCCC(NC(=O)[C@@H](Cc1c([nH]c2ccccc12)C#N)NC(=O)C(NC(=O)N1[C@@H](C)CCC[C@H]1C)C(C)C)C(O)=O	InChI=1S/C31H44N6O5/c1-6-7-14-24(30(40)41)34-28(38)25(16-22-21-13-8-9-15-23(21)33-26(22)17-32)35-29(39)27(18(2)3)36-31(42)37-19(4)11-10-12-20(37)5/h8-9,13,15,18-20,24-25,27,33H,6-7,10-12,14,16H2,1-5H3,(H,34,38)(H,35,39)(H,36,42)(H,40,41)/t19-,20+,24?,25-,27?/m1/s1	WTIMYTIFDDIBIP-PTKGVPPSSA-N	50051388	2-((R)-3-(2-Cyano-1H-indol-3-yl)-2-{2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-3-methyl-butyrylamino}-propionylamino)-hexanoic acid::CHEMBL306123	Endothelin-1 receptor			 2400							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051388&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314579	103948386		CHEMBL306123				ZINC26398399	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50776236	CCSCC(NC(=O)[C@@H](Cc1c(Br)[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(O)=O	InChI=1S/C30H44BrN5O5S/c1-6-42-16-25(29(39)40)34-28(38)24(15-21-20-12-7-8-13-22(20)32-26(21)31)33-27(37)23(14-17(2)3)35-30(41)36-18(4)10-9-11-19(36)5/h7-8,12-13,17-19,23-25,32H,6,9-11,14-16H2,1-5H3,(H,33,37)(H,34,38)(H,35,41)(H,39,40)/t18-,19+,23?,24-,25?/m1/s1	LZBDEPUGFFURHL-JIJGDNSHSA-N	50051406	2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-4-methyl-pentanoylamino}-propionylamino)-3-ethylsulfanyl-propionic acid::CHEMBL305524	Endothelin-1 receptor			 6.4							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051406&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44315008	103948404		CHEMBL305524				ZINC26393942	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781536	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)N(C)C(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-9-30(5)43(47(63)55-39(51(67)68)26-35-28-52-37-24-18-17-23-36(35)37)57-48(64)44(31(6)10-2)56-46(62)40(27-41(60)61)58(8)50(66)38(25-29(3)4)54-49(65)45(53-32(7)59)42(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,28-31,38-40,42-45,52H,9-10,25-27H2,1-8H3,(H,53,59)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	UFAYTJZYHSQRAW-KUIIPSLPSA-N	50369271	CHEMBL1793934	Endothelin-1 receptor			 3200							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369271&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56681799	160848373		CHEMBL1793934					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781537	CC[C@@H](C)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)CNC(=O)[C@H](NC(=O)[C@H](N)Cc1c[nH]c2ccccc12)[C@H](C)CC	InChI=1S/C51H68N8O9/c1-8-30(5)44(41(61)28-54-50(67)45(31(6)9-2)59-47(64)37(52)25-35-27-53-38-23-17-16-22-36(35)38)58-49(66)40(26-42(62)63)56-48(65)39(24-29(3)4)57-51(68)46(55-32(7)60)43(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,27,29-31,37,39-40,43-46,53H,8-9,24-26,28,52H2,1-7H3,(H,54,67)(H,55,60)(H,56,65)(H,57,68)(H,58,66)(H,59,64)(H,62,63)/t30-,31-,37-,39+,40+,44-,45-,46+/m1/s1	CGCBRXFRVJPFHT-MDVOOFEXSA-N	50369264	CHEMBL1793929	Endothelin-1 receptor			 260							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56681798	160848366		CHEMBL1793929					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781540	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(c1ccccc1)c1ccccc1)N(C)C(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-9-30(5)43(48(64)55-40(51(67)68)26-35-28-52-37-24-18-17-23-36(35)37)57-49(65)44(31(6)10-2)56-47(63)39(27-41(60)61)53-46(62)38(25-29(3)4)54-50(66)45(58(8)32(7)59)42(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,28-31,38-40,42-45,52H,9-10,25-27H2,1-8H3,(H,53,62)(H,54,66)(H,55,64)(H,56,63)(H,57,65)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	KZRQNWOEVPOLQO-KUIIPSLPSA-N	50369272	CHEMBL1793927	Endothelin-1 receptor			 4500							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369272&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56678451	160848374		CHEMBL1793927					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781542	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N(C)[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C51H67N7O10/c1-9-30(5)43(48(64)57-44(31(6)10-2)50(66)58(8)40(51(67)68)26-35-28-52-37-24-18-17-23-36(35)37)56-47(63)39(27-41(60)61)54-46(62)38(25-29(3)4)55-49(65)45(53-32(7)59)42(33-19-13-11-14-20-33)34-21-15-12-16-22-34/h11-24,28-31,38-40,42-45,52H,9-10,25-27H2,1-8H3,(H,53,59)(H,54,62)(H,55,65)(H,56,63)(H,57,64)(H,60,61)(H,67,68)/t30-,31-,38-,39-,40-,43-,44-,45-/m0/s1	JZKPZWKHHIHIIM-KUIIPSLPSA-N	50369274	CHEMBL2367550	Endothelin-1 receptor			 11000							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369274&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73354330	160848376		CHEMBL2367550					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781544	CC[C@H](C)[C@H](NC(=O)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@H](C)CC)C(=O)CNC(=O)[C@H](N)Cc1c[nH]c2ccccc12	InChI=1S/C51H68N8O9/c1-8-30(5)44(41(61)28-54-47(64)37(52)25-35-27-53-38-23-17-16-22-36(35)38)58-50(67)45(31(6)9-2)59-49(66)40(26-42(62)63)56-48(65)39(24-29(3)4)57-51(68)46(55-32(7)60)43(33-18-12-10-13-19-33)34-20-14-11-15-21-34/h10-23,27,29-31,37,39-40,43-46,53H,8-9,24-26,28,52H2,1-7H3,(H,54,64)(H,55,60)(H,56,65)(H,57,68)(H,58,67)(H,59,66)(H,62,63)/t30-,31+,37+,39-,40-,44-,45+,46-/m0/s1	HYKBICDYDPTWDJ-SLICBABFSA-N	50369265	CHEMBL1793928	Endothelin-1 receptor			 880							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			56678452	160848367		CHEMBL1793928					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50781546	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(C)=O)C1c2ccccc2CCc2ccccc12)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C52H67N7O10/c1-8-29(5)44(49(65)57-41(52(68)69)25-34-27-53-38-21-15-14-18-35(34)38)59-50(66)45(30(6)9-2)58-48(64)40(26-42(61)62)55-47(63)39(24-28(3)4)56-51(67)46(54-31(7)60)43-36-19-12-10-16-32(36)22-23-33-17-11-13-20-37(33)43/h10-21,27-30,39-41,43-46,53H,8-9,22-26H2,1-7H3,(H,54,60)(H,55,63)(H,56,67)(H,57,65)(H,58,64)(H,59,66)(H,61,62)(H,68,69)/t29-,30-,39-,40-,41-,44-,45-,46-/m0/s1	HRAQSWKGRRUBDJ-FFEQYNEASA-N	50032181	2-{1-[1-(2-carboxy-1-{1-[10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl(methylcarboxamido)methylcarboxamido]-3-methylbutylcarboxamido}ethylcarboxamido)-2-methylbutylcarboxamido]-2-methylbutylcarboxamido}-3-(1H-3-indolyl)propanoic acid::3-{2-[2-Acetylamino-2-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-acetylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL262993	Endothelin-1 receptor			 4							ChEMBL	10.1021/jm970161m	10.7270/Q24T6K1W	9216842			Cody, WL; He, JX; Reily, MD; Haleen, SJ; Walker, DM; Reyner, EL; Stewart, BH; Doherty, AM	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032181&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44304492	103940731		CHEMBL262993					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50776304	CCCCC(NC(=O)[C@@H](Cc1c(Br)[nH]c2ccccc12)NC(=O)C(NC(=O)N1[C@@H](C)CCC[C@H]1C)C1CC1)C(O)=O	InChI=1S/C30H42BrN5O5/c1-4-5-12-23(29(39)40)33-27(37)24(16-21-20-11-6-7-13-22(20)32-26(21)31)34-28(38)25(19-14-15-19)35-30(41)36-17(2)9-8-10-18(36)3/h6-7,11,13,17-19,23-25,32H,4-5,8-10,12,14-16H2,1-3H3,(H,33,37)(H,34,38)(H,35,41)(H,39,40)/t17-,18+,23?,24-,25?/m1/s1	XDNAXXIOBHFZDQ-OOTXOBGZSA-N	50051385	2-((R)-3-(2-Bromo-1H-indol-3-yl)-2-{2-cyclopropyl-2-[((2S,6R)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-acetylamino}-propionylamino)-hexanoic acid::CHEMBL73925	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm9600914	10.7270/Q2XS5W2G	8691426			Fukami, T; Yamakawa, T; Niiyama, K; Kojima, H; Amano, Y; Kanda, F; Ozaki, S; Fukuroda, T; Ihara, M; Yano, M; Ishikawa, K	Tsukuba Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051385&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44314619	103948383		CHEMBL73925				ZINC26387530	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50764996	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C55H69N7O8/c1-8-34(5)47(52(66)60-45(55(69)70)31-40-32-56-42-28-20-19-27-41(40)42)62-53(67)48(35(6)9-2)61-51(65)44(30-37-21-13-10-14-22-37)58-50(64)43(29-33(3)4)59-54(68)49(57-36(7)63)46(38-23-15-11-16-24-38)39-25-17-12-18-26-39/h10-28,32-35,43-49,56H,8-9,29-31H2,1-7H3,(H,57,63)(H,58,64)(H,59,68)(H,60,66)(H,61,65)(H,62,67)(H,69,70)/t34-,35-,43-,44-,45-,47-,48-,49+/m0/s1	WTUKWAHKXMTYEJ-GAQYKUSUSA-N	50045224	Ac-D-Dip-Leu-Phe-Ile-Ile-Trp::CHEMBL387200	Endothelin-1 receptor					 580					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045224	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045224&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10102392	103976315		CHEMBL387200					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50764998	CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H62N8O10/c1-6-26(4)38(43(60)51-36(44(61)62)22-29-24-46-31-17-11-10-16-30(29)31)52-39(56)32(18-12-13-19-45)48-42(59)35(23-37(54)55)50-40(57)33(20-25(2)3)49-41(58)34(47-27(5)53)21-28-14-8-7-9-15-28/h7-11,14-17,24-26,32-36,38,46H,6,12-13,18-23,45H2,1-5H3,(H,47,53)(H,48,59)(H,49,58)(H,50,57)(H,51,60)(H,52,56)(H,54,55)(H,61,62)/t26-,32-,33-,34+,35-,36-,38-/m0/s1	PBVZCMVAAPBADM-LXXNTRSASA-N	50045229	Ac-D-Phe-Leu-Asp-Lys-Ile-Trp::CHEMBL314239	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045229&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320780	103976320		CHEMBL314239					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50764999	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H60N8O10/c1-6-24(3)36(41(58)49-34(43(60)61)21-28-23-45-30-17-12-11-16-29(28)30)51-42(59)37(25(4)7-2)50-40(57)33(22-35(53)54)48-38(55)31(18-13-19-44)47-39(56)32(46-26(5)52)20-27-14-9-8-10-15-27/h8-12,14-17,23-25,31-34,36-37,45H,6-7,13,18-22,44H2,1-5H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t24-,25-,31-,32+,33-,34-,36-,37-/m0/s1	WXVKATPLQWNUHO-POYKSISPSA-N	50045227	(S)-3-[2-((R)-2-Acetylamino-3-phenyl-propionylamino)-5-amino-pentanoylamino]-N-{(S)-1-[(S)-1-((S)-carboxy-2-(S)-1-1H-indol-3-yl-ethylcarbamoyl)-2-(S)-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Orn-Asp-Ile-Ile-Trp::CHEMBL2370070	Endothelin-1 receptor			 2450							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045227	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045227&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73356095	103976318		CHEMBL2370070				ZINC95610422	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765000	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(Cc1cnc[nH]1)C(O)=O	InChI=1S/C39H58N8O10/c1-8-22(5)32(37(54)45-30(39(56)57)17-26-19-40-20-41-26)47-38(55)33(23(6)9-2)46-36(53)29(18-31(49)50)44-34(51)27(15-21(3)4)43-35(52)28(42-24(7)48)16-25-13-11-10-12-14-25/h10-14,19-23,27-30,32-33H,8-9,15-18H2,1-7H3,(H,40,41)(H,42,48)(H,43,52)(H,44,51)(H,45,54)(H,46,53)(H,47,55)(H,49,50)(H,56,57)/t22-,23-,27-,28+,29-,30?,32-,33-/m0/s1	FCHVBJPUWRSWLL-AJPQGBEXSA-N	50045226	Ac-D-Phe-Leu-Asp-Ile-Ile-DL-His::CHEMBL89416	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045226	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045226&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321080	103976317		CHEMBL89416				ZINC95541722	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765006	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C38H50N6O9/c1-6-22(4)33(37(51)43-31(38(52)53)18-25-20-39-27-15-11-10-14-26(25)27)44-36(50)30(19-32(46)47)42-34(48)28(16-21(2)3)41-35(49)29(40-23(5)45)17-24-12-8-7-9-13-24/h7-15,20-22,28-31,33,39H,6,16-19H2,1-5H3,(H,40,45)(H,41,49)(H,42,48)(H,43,51)(H,44,50)(H,46,47)(H,52,53)/t22-,28-,29+,30-,31-,33-/m0/s1	RKEZXGDDBOFKKM-HRHWTSPYSA-N	50045235	(S)-3-[(R)-2-((1S,5S)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(S)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Leu-Asp-Ile-Trp::CHEMBL87724	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321075	103976326		CHEMBL87724				ZINC26575973	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765007	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O	InChI=1S/C48H64N6O11/c1-8-28(5)40(45(61)52-37(48(64)65)25-31-20-22-34(56)23-21-31)54-46(62)41(29(6)9-2)53-44(60)36(26-38(57)58)50-43(59)35(24-27(3)4)51-47(63)42(49-30(7)55)39(32-16-12-10-13-17-32)33-18-14-11-15-19-33/h10-23,27-29,35-37,39-42,56H,8-9,24-26H2,1-7H3,(H,49,55)(H,50,59)(H,51,63)(H,52,61)(H,53,60)(H,54,62)(H,57,58)(H,64,65)/t28-,29-,35-,36-,37-,40-,41-,42+/m0/s1	QXIDYPVHAGHZKK-BKUMABEESA-N	50045234	Ac-D-Dip-Leu-Asp-Ile-Ile-Tyr::CHEMBL313344	Endothelin-1 receptor					 2700					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045234&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10395969	103976325		CHEMBL313344					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765009	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C48H63N7O10/c1-8-27(5)41(46(62)53-39(48(64)65)23-33-25-49-35-17-13-12-16-34(33)35)55-47(63)42(28(6)9-2)54-45(61)38(24-40(57)58)52-43(59)36(20-26(3)4)51-44(60)37(50-29(7)56)22-30-18-19-31-14-10-11-15-32(31)21-30/h10-19,21,25-28,36-39,41-42,49H,8-9,20,22-24H2,1-7H3,(H,50,56)(H,51,60)(H,52,59)(H,53,62)(H,54,61)(H,55,63)(H,57,58)(H,64,65)/t27-,28-,36-,37+,38-,39-,41-,42-/m0/s1	JSGRPPGXQMIRRM-MKZJQENTSA-N	50001221	3-[2-(2-Acetylamino-3-naphthalen-2-yl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL315047	Endothelin-1 receptor			 1000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001221&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297025	103915686		CHEMBL315047					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765012	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C42H59N7O9/c1-7-24(5)35(40(55)47-33(42(57)58)20-27-22-44-30-17-13-12-16-28(27)30)49-41(56)36(25(6)8-2)48-39(54)32(21-34(50)51)46-38(53)31(18-23(3)4)45-37(52)29(43)19-26-14-10-9-11-15-26/h9-17,22-25,29,31-33,35-36,44H,7-8,18-21,43H2,1-6H3,(H,45,52)(H,46,53)(H,47,55)(H,48,54)(H,49,56)(H,50,51)(H,57,58)/t24-,25-,29-,31-,32-,33-,35-,36-/m0/s1	MFRKVXMTBRZSQE-MFNJSQIASA-N	50045238	CHEMBL87252::Phe-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor			>100000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045238&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321125	103976329		CHEMBL87252				ZINC95544667	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765015	CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H48N6O9/c1-4-24(2)36(40(54)46-34(41(55)56)21-28-23-42-30-18-12-11-17-29(28)30)47-39(53)32(20-27-15-9-6-10-16-27)44-38(52)33(22-35(49)50)45-37(51)31(43-25(3)48)19-26-13-7-5-8-14-26/h5-18,23-24,31-34,36,42H,4,19-22H2,1-3H3,(H,43,48)(H,44,52)(H,45,51)(H,46,54)(H,47,53)(H,49,50)(H,55,56)/t24-,31+,32-,33-,34-,36-/m0/s1	PMIVOVLKFBOQEE-QSOPEXJISA-N	50045242	Ac-D-Phe-Asp-Phe-Ile-Trp::CHEMBL316092	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045242&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321031	103976333		CHEMBL316092				ZINC95542449	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765021	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C34H45N5O6/c1-6-20(3)29(32(42)37-28(34(44)45)18-24-19-35-26-16-12-11-15-25(24)26)39-33(43)30(21(4)7-2)38-31(41)27(36-22(5)40)17-23-13-9-8-10-14-23/h8-16,19-21,27-30,35H,6-7,17-18H2,1-5H3,(H,36,40)(H,37,42)(H,38,41)(H,39,43)(H,44,45)/t20-,21-,27+,28-,29-,30-/m0/s1	KSMIQAULFAKWPP-VIPNTURPSA-N	50045247	3-((R)-2-Acetylamino-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-((S)-(S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Ile-Ile-Trp::CHEMBL312916	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045247&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321073	103976338		CHEMBL312916				ZINC26576451	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765022	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H63N7O10/c1-8-29(6)42(47(63)55-41(28(4)5)46(62)54-38(49(65)66)24-33-26-50-35-22-16-15-21-34(33)35)56-45(61)37(25-39(58)59)52-44(60)36(23-27(2)3)53-48(64)43(51-30(7)57)40(31-17-11-9-12-18-31)32-19-13-10-14-20-32/h9-22,26-29,36-38,40-43,50H,8,23-25H2,1-7H3,(H,51,57)(H,52,60)(H,53,64)(H,54,62)(H,55,63)(H,56,61)(H,58,59)(H,65,66)/t29-,36-,37-,38-,41-,42-,43+/m0/s1	RVWZNRWHSOBHCH-YSMMXTGPSA-N	50045249	Ac-D-Dip-Leu-Asp-Ile-Val-Trp::CHEMBL86703	Endothelin-1 receptor					 6000					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045249&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10033723	103976340		CHEMBL86703					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765024	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33-,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-KTCACYFJSA-N	50045248	(S)-3-[(S)-2-((S)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-Phe-Leu-Asp-Ile-Ile-Trp::CHEMBL273391	Endothelin-1 receptor			 18400							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045248&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321103	103976339		CHEMBL273391				ZINC95541374	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765034	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C37H46N6O11/c1-4-20(2)32(36(52)42-29(37(53)54)17-23-19-38-25-13-9-8-12-24(23)25)43-35(51)28(18-31(47)48)41-33(49)26(14-15-30(45)46)40-34(50)27(39-21(3)44)16-22-10-6-5-7-11-22/h5-13,19-20,26-29,32,38H,4,14-18H2,1-3H3,(H,39,44)(H,40,50)(H,41,49)(H,42,52)(H,43,51)(H,45,46)(H,47,48)(H,53,54)/t20-,26-,27+,28-,29-,32-/m0/s1	VAUYLEZGYRQZIQ-MBGINICSSA-N	50045243	Ac-D-Phe-Glu-Asp-Ile-Trp::CHEMBL313056	Endothelin-1 receptor			 930							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045243&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321124	103976334		CHEMBL313056				ZINC95610409	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765038	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O	InChI=1S/C42H60N6O11/c1-8-24(5)35(40(56)46-33(42(58)59)21-28-15-17-29(50)18-16-28)48-41(57)36(25(6)9-2)47-39(55)32(22-34(51)52)45-37(53)30(19-23(3)4)44-38(54)31(43-26(7)49)20-27-13-11-10-12-14-27/h10-18,23-25,30-33,35-36,50H,8-9,19-22H2,1-7H3,(H,43,49)(H,44,54)(H,45,53)(H,46,56)(H,47,55)(H,48,57)(H,51,52)(H,58,59)/t24-,25-,30-,31+,32-,33-,35-,36-/m0/s1	JQXRKILDGXHWOW-JVHVIEOWSA-N	50045257	Ac-D-Phe-Leu-Asp-Ile-Ile-Tyr::CHEMBL89736	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321132	103976348		CHEMBL89736				ZINC95544704	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765040	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H64N8O10/c1-6-28(3)41(46(63)55-38(49(66)67)25-33-27-51-35-22-15-14-21-34(33)35)57-47(64)42(29(4)7-2)56-45(62)37(26-39(59)60)54-44(61)36(23-16-24-50)53-48(65)43(52-30(5)58)40(31-17-10-8-11-18-31)32-19-12-9-13-20-32/h8-15,17-22,27-29,36-38,40-43,51H,6-7,16,23-26,50H2,1-5H3,(H,52,58)(H,53,65)(H,54,61)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t28-,29-,36-,37-,38-,41-,42-,43+/m0/s1	IEJDKICPBODJMQ-UDGKXYKTSA-N	50045246	Ac-D-Dip-Orn-Asp-Ile-Ile-Trp::CHEMBL2370066	Endothelin-1 receptor					 13					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045246&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73345435	103976337		CHEMBL2370066					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765042	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/t29-,30-,37-,38-,39-,42-,43-,44+/m0/s1	XUMJJSAQQCTKAO-LAJITBNKSA-N	50045239	Ac-D-Dip-Leu-Asp-Ile-Ile-Trp::Ac-D-Dip-Leu-Asp-Ile-Ile-Trp.di sodium salt::CHEMBL313760	Endothelin-1 receptor			 140							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045239&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9811968	103976330		CHEMBL313760					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765044	CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H57N7O12/c1-6-24(4)37(42(60)49-34(43(61)62)20-27-22-44-29-15-11-10-14-28(27)29)50-38(56)30(16-17-35(52)53)46-41(59)33(21-36(54)55)48-39(57)31(18-23(2)3)47-40(58)32(45-25(5)51)19-26-12-8-7-9-13-26/h7-15,22-24,30-34,37,44H,6,16-21H2,1-5H3,(H,45,51)(H,46,59)(H,47,58)(H,48,57)(H,49,60)(H,50,56)(H,52,53)(H,54,55)(H,61,62)/t24-,30-,31-,32+,33-,34-,37-/m0/s1	SGETWGXIQQHWOQ-BZFYIXCDSA-N	50045232	Ac-D-Phe-Leu-Asp-Glu-Ile-Trp::CHEMBL431874	Endothelin-1 receptor			 6700							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045232&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320906	103976323		CHEMBL431874					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765045	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C46H62N8O10/c1-8-25(5)39(44(61)52-37(46(63)64)20-29-23-48-33-17-13-11-15-31(29)33)54-45(62)40(26(6)9-2)53-43(60)36(21-38(56)57)51-41(58)34(18-24(3)4)50-42(59)35(49-27(7)55)19-28-22-47-32-16-12-10-14-30(28)32/h10-17,22-26,34-37,39-40,47-48H,8-9,18-21H2,1-7H3,(H,49,55)(H,50,59)(H,51,58)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t25-,26-,34-,35-,36-,37-,39-,40-/m0/s1	ZYNCQGUPXUKGPO-VXEKNHJASA-N	50045230	Ac-D-Trp-Leu-Asp-Ile-Ile-Trp::CHEMBL313382	Endothelin-1 receptor			 1800							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045230	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045230&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320735	103976321		CHEMBL313382					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765046	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](N)C(c1ccccc1)c1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C=O	InChI=1S/C48H63N7O8/c1-7-29(5)42(47(62)51-34(27-56)24-33-26-50-36-22-16-15-21-35(33)36)55-48(63)43(30(6)8-2)54-45(60)38(25-39(57)58)52-44(59)37(23-28(3)4)53-46(61)41(49)40(31-17-11-9-12-18-31)32-19-13-10-14-20-32/h9-22,26-30,34,37-38,40-43,50H,7-8,23-25,49H2,1-6H3,(H,51,62)(H,52,59)(H,53,61)(H,54,60)(H,55,63)(H,57,58)/t29-,30-,34-,37-,38-,41+,42-,43-/m0/s1	JQAKPHZWHZZOJY-RDDBSUKJSA-N	50045256	CHEMBL2370067::D-Dip-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor					 1900					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045256&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			73350041	103976347		CHEMBL2370067					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765050	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C46H68N8O8/c1-8-28(5)39(44(59)52-38(46(61)62)25-32-26-48-34-20-14-13-19-33(32)34)54-45(60)40(29(6)9-2)53-41(56)35(21-15-16-22-47)50-42(57)36(23-27(3)4)51-43(58)37(49-30(7)55)24-31-17-11-10-12-18-31/h10-14,17-20,26-29,35-40,48H,8-9,15-16,21-25,47H2,1-7H3,(H,49,55)(H,50,57)(H,51,58)(H,52,59)(H,53,56)(H,54,60)(H,61,62)/t28-,29-,35-,36-,37+,38-,39-,40-/m0/s1	DYCJTRVZUAXNDM-POHSHLOQSA-N	50045260	Ac-D-Phe-Leu-Lys-Ile-Ile-Trp::CHEMBL431218	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320908	103976351		CHEMBL431218					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765053	CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H55N7O10/c1-7-23(4)35(40(56)47-33(41(57)58)19-27-21-42-29-16-12-11-15-28(27)29)48-36(52)24(5)43-37(53)32(20-34(50)51)46-38(54)30(17-22(2)3)45-39(55)31(44-25(6)49)18-26-13-9-8-10-14-26/h8-16,21-24,30-33,35,42H,7,17-20H2,1-6H3,(H,43,53)(H,44,49)(H,45,55)(H,46,54)(H,47,56)(H,48,52)(H,50,51)(H,57,58)/t23-,24-,30-,31+,32-,33-,35-/m0/s1	XNJFELJOLDLUDV-DTQZHFBISA-N	50045237	Ac-D-Phe-Leu-Asp-Ala-Ile-Trp::CHEMBL87243	Endothelin-1 receptor			 3600							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045237&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320907	103976328		CHEMBL87243				ZINC95542107	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765054	CC[C@H](C)[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C28H34N4O5/c1-4-17(2)25(32-26(34)23(30-18(3)33)14-19-10-6-5-7-11-19)27(35)31-24(28(36)37)15-20-16-29-22-13-9-8-12-21(20)22/h5-13,16-17,23-25,29H,4,14-15H2,1-3H3,(H,30,33)(H,31,35)(H,32,34)(H,36,37)/t17-,23+,24-,25-/m0/s1	GOQQMBMRNCMDQC-VUHWMDJISA-N	50045258	(S)-2-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-3-methyl-pentanoylamino]-3-(1H-indol-3-yl)-propionic acid::Ac-D-Phe-Ile-Trp::CHEMBL330489	Endothelin-1 receptor			 8000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321032	103976349		CHEMBL330489				ZINC26578160	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765059	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](C(O)=O)c1csc2ccccc12	InChI=1S/C43H58N6O10S/c1-8-24(5)35(41(56)48-36(25(6)9-2)42(57)49-37(43(58)59)29-22-60-33-18-14-13-17-28(29)33)47-40(55)32(21-34(51)52)46-38(53)30(19-23(3)4)45-39(54)31(44-26(7)50)20-27-15-11-10-12-16-27/h10-18,22-25,30-32,35-37H,8-9,19-21H2,1-7H3,(H,44,50)(H,45,54)(H,46,53)(H,47,55)(H,48,56)(H,49,57)(H,51,52)(H,58,59)/t24-,25-,30-,31+,32-,35-,36-,37-/m0/s1	PGHGRJJXBOQOPS-PKJZTKIMSA-N	50045250	Ac-D-Phe-Leu-Asp-Ile-Ile-Bta::CHEMBL315780	Endothelin-1 receptor			 14000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045250&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321131	103976341		CHEMBL315780					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765060	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H63N7O10/c1-8-29(6)42(47(63)54-38(49(65)66)24-33-26-50-35-22-16-15-21-34(33)35)56-46(62)41(28(4)5)55-45(61)37(25-39(58)59)52-44(60)36(23-27(2)3)53-48(64)43(51-30(7)57)40(31-17-11-9-12-18-31)32-19-13-10-14-20-32/h9-22,26-29,36-38,40-43,50H,8,23-25H2,1-7H3,(H,51,57)(H,52,60)(H,53,64)(H,54,63)(H,55,61)(H,56,62)(H,58,59)(H,65,66)/t29-,36-,37-,38-,41-,42-,43+/m0/s1	DRQGVADKIBRYTL-YSMMXTGPSA-N	50045264	Ac-D-Dip-Leu-Asp-Val-Ile-Trp::CHEMBL315841	Endothelin-1 receptor					 17					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10056613	103976355		CHEMBL315841					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765061	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H54N6O8/c1-6-25(3)37(41(54)47-36(43(56)57)23-30-24-44-33-16-12-11-15-32(30)33)49-42(55)38(26(4)7-2)48-40(53)35(22-29-17-19-31(51)20-18-29)46-39(52)34(45-27(5)50)21-28-13-9-8-10-14-28/h8-20,24-26,34-38,44,51H,6-7,21-23H2,1-5H3,(H,45,50)(H,46,52)(H,47,54)(H,48,53)(H,49,55)(H,56,57)/t25-,26-,34+,35-,36-,37-,38-/m0/s1	GFCOMJOGVMUFPE-OSXYACSBSA-N	50045252	Ac-D-Phe-Tyr-Ile-Ile-Trp::CHEMBL315384	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045252&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321074	103976343		CHEMBL315384				ZINC95610394	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765062	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H55N7O10/c1-7-22(3)34(39(55)46-32(41(57)58)19-27-21-42-29-17-13-12-16-28(27)29)48-40(56)35(23(4)8-2)47-38(54)31(20-33(50)51)45-36(52)24(5)43-37(53)30(44-25(6)49)18-26-14-10-9-11-15-26/h9-17,21-24,30-32,34-35,42H,7-8,18-20H2,1-6H3,(H,43,53)(H,44,49)(H,45,52)(H,46,55)(H,47,54)(H,48,56)(H,50,51)(H,57,58)/t22-,23-,24-,30+,31-,32-,34-,35-/m0/s1	IWSSIMWXLDYURU-VDRLPZNMSA-N	50045262	Ac-D-Phe-Ala-Asp-Ile-Ile-Trp::CHEMBL406279	Endothelin-1 receptor			 420							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321119	103976353		CHEMBL406279				ZINC95613588	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765071	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O11/c1-8-24(5)37(42(59)49-35(44(61)62)20-28-22-45-31-13-11-10-12-30(28)31)51-43(60)38(25(6)9-2)50-41(58)34(21-36(54)55)48-39(56)32(18-23(3)4)47-40(57)33(46-26(7)52)19-27-14-16-29(53)17-15-27/h10-17,22-25,32-35,37-38,45,53H,8-9,18-21H2,1-7H3,(H,46,52)(H,47,57)(H,48,56)(H,49,59)(H,50,58)(H,51,60)(H,54,55)(H,61,62)/t24-,25-,32-,33+,34-,35-,37-,38-/m0/s1	KGENNXUISWGQKL-ZDRDUBIJSA-N	50001219	3-{2-[2-Acetylamino-3-(4-hydroxy-phenyl)-propionylamino]-4-methyl-pentanoylamino}-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL85341	Endothelin-1 receptor			 7000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001219&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321030	103915684		CHEMBL85341					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765073	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C38H50N6O9/c1-6-21(3)32(36(50)42-30(38(52)53)18-25-20-39-27-16-12-11-15-26(25)27)44-37(51)33(22(4)7-2)43-35(49)29(19-31(46)47)41-34(48)28(40-23(5)45)17-24-13-9-8-10-14-24/h8-16,20-22,28-30,32-33,39H,6-7,17-19H2,1-5H3,(H,40,45)(H,41,48)(H,42,50)(H,43,49)(H,44,51)(H,46,47)(H,52,53)/t21-,22-,28+,29-,30-,32-,33-/m0/s1	XYVDWQKXXNSVGP-MGIIKFKASA-N	50045251	3-((R)-2-Acetylamino-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-((S)-(S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-Asp-Ile-Ile-Trp::CHEMBL315658	Endothelin-1 receptor			 9100							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045251&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321033	103976342		CHEMBL315658				ZINC26578236	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765079	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H65N7O8/c1-8-30(5)42(47(61)54-41(49(63)64)27-35-28-50-37-23-17-16-22-36(35)37)56-48(62)43(31(6)9-2)55-46(60)40(26-34-20-14-11-15-21-34)53-44(58)38(24-29(3)4)52-45(59)39(51-32(7)57)25-33-18-12-10-13-19-33/h10-23,28-31,38-43,50H,8-9,24-27H2,1-7H3,(H,51,57)(H,52,59)(H,53,58)(H,54,61)(H,55,60)(H,56,62)(H,63,64)/t30-,31-,38-,39+,40-,41-,42-,43-/m0/s1	BQFWUVDRXODPBL-HZNXMSJUSA-N	50045240	(S)-2-[(S)-2-((2S,5S)-2-{(S)-2-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-3-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-(S)-1H-indol-3-yl-propionic acid::Ac-D-Phe-Leu-Phe-Ile-Ile-Trp::CHEMBL327350	Endothelin-1 receptor			 1400							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045240&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321081	103976331		CHEMBL327350					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765084	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](N)Cc1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C42H59N7O9/c1-7-24(5)35(40(55)47-33(42(57)58)20-27-22-44-30-17-13-12-16-28(27)30)49-41(56)36(25(6)8-2)48-39(54)32(21-34(50)51)46-38(53)31(18-23(3)4)45-37(52)29(43)19-26-14-10-9-11-15-26/h9-17,22-25,29,31-33,35-36,44H,7-8,18-21,43H2,1-6H3,(H,45,52)(H,46,53)(H,47,55)(H,48,54)(H,49,56)(H,50,51)(H,57,58)/t24-,25-,29+,31-,32-,33-,35-,36-/m0/s1	MFRKVXMTBRZSQE-ZGPTWHFNSA-N	50045265	CHEMBL315328::D-Phe-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor			>10000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321104	103976356		CHEMBL315328				ZINC95540500	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765085	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C50H65N7O10/c1-8-29(5)43(48(64)55-41(50(66)67)25-35-27-51-37-18-14-13-17-36(35)37)57-49(65)44(30(6)9-2)56-47(63)40(26-42(59)60)54-45(61)38(23-28(3)4)53-46(62)39(52-31(7)58)24-32-19-21-34(22-20-32)33-15-11-10-12-16-33/h10-22,27-30,38-41,43-44,51H,8-9,23-26H2,1-7H3,(H,52,58)(H,53,62)(H,54,61)(H,55,64)(H,56,63)(H,57,65)(H,59,60)(H,66,67)/t29-,30-,38-,39+,40-,41-,43-,44-/m0/s1	IFDNLSRYZKUGIR-KXXXQFFTSA-N	50001218	3-[2-(2-Acetylamino-3-biphenyl-4-yl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL438194	Endothelin-1 receptor			 3500							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001218&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122149	103915683		CHEMBL438194					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765089	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C49H61N7O12/c1-6-27(3)41(46(64)54-37(49(67)68)24-32-26-50-34-21-15-14-20-33(32)34)56-47(65)42(28(4)7-2)55-45(63)36(25-39(60)61)53-44(62)35(22-23-38(58)59)52-48(66)43(51-29(5)57)40(30-16-10-8-11-17-30)31-18-12-9-13-19-31/h8-21,26-28,35-37,40-43,50H,6-7,22-25H2,1-5H3,(H,51,57)(H,52,66)(H,53,62)(H,54,64)(H,55,63)(H,56,65)(H,58,59)(H,60,61)(H,67,68)/t27-,28-,35-,36-,37-,41-,42-,43+/m0/s1	OVTDDVGHCAWGJB-AAHGXADTSA-N	50045263	Ac-D-Dip-Glu-Asp-Ile-Ile-Trp::CHEMBL407269	Endothelin-1 receptor					 25					ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321082	103976354		CHEMBL407269					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765090	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C41H55N7O10/c1-7-23(4)35(40(56)43-24(5)36(52)47-33(41(57)58)19-27-21-42-29-16-12-11-15-28(27)29)48-39(55)32(20-34(50)51)46-37(53)30(17-22(2)3)45-38(54)31(44-25(6)49)18-26-13-9-8-10-14-26/h8-16,21-24,30-33,35,42H,7,17-20H2,1-6H3,(H,43,56)(H,44,49)(H,45,54)(H,46,53)(H,47,52)(H,48,55)(H,50,51)(H,57,58)/t23-,24-,30-,31+,32-,33-,35-/m0/s1	NJCZWMGWYONMBK-DTQZHFBISA-N	50045225	Ac-D-Phe-Leu-Asp-Ile-Ala-Trp::CHEMBL86737	Endothelin-1 receptor			 8000							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045225	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045225&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44320779	103976316		CHEMBL86737				ZINC95544639	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765098	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC([O-])=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c1ccccc1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C([O-])=O	InChI=1S/C50H65N7O10/c1-8-29(5)42(47(63)55-39(50(66)67)25-34-27-51-36-23-17-16-22-35(34)36)57-48(64)43(30(6)9-2)56-46(62)38(26-40(59)60)53-45(61)37(24-28(3)4)54-49(65)44(52-31(7)58)41(32-18-12-10-13-19-32)33-20-14-11-15-21-33/h10-23,27-30,37-39,41-44,51H,8-9,24-26H2,1-7H3,(H,52,58)(H,53,61)(H,54,65)(H,55,63)(H,56,62)(H,57,64)(H,59,60)(H,66,67)/p-2/t29-,30-,37-,38-,39-,42-,43-,44+/m0/s1	XUMJJSAQQCTKAO-LAJITBNKSA-L	50368647	CHEMBL1788127	Endothelin-1 receptor			 60							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368647&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91930339	160847749		CHEMBL1788127					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50765099	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33+,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-YNIJNJSISA-N	50001217	3-[2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL86814	Endothelin-1 receptor			 1800							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001217&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297023	103915682		CHEMBL86814				ZINC95610946	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788259	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccn2)c1C	InChI=1S/C16H15N3O3S/c1-11-12(2)18-22-16(11)19-23(20,21)15-9-4-3-7-13(15)14-8-5-6-10-17-14/h3-10,19H,1-2H3	CJGOHKQDMMUKLK-UHFFFAOYSA-N	50068689	CHEMBL149018::N-(3,4-Dimethyl-isoxazol-5-yl)-2-pyridin-2-yl-benzenesulfonamide	Endothelin-1 receptor		 820								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068689&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9949368	103962881		CHEMBL149018				ZINC00024073	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788265	Cc1noc(NS(=O)(=O)c2ccccc2-c2cc3ccccc3[nH]2)c1C	InChI=1S/C19H17N3O3S/c1-12-13(2)21-25-19(12)22-26(23,24)18-10-6-4-8-15(18)17-11-14-7-3-5-9-16(14)20-17/h3-11,20,22H,1-2H3	DDHYLTHTVGYIBP-UHFFFAOYSA-N	50068696	CHEMBL148967::N-(3,4-Dimethyl-isoxazol-5-yl)-2-(1H-indol-2-yl)-benzenesulfonamide	Endothelin-1 receptor		 340								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068696&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9864017	103962888		CHEMBL148967				ZINC03923832	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788280	Cc1noc(NS(=O)(=O)c2ccccc2-c2cccnc2)c1C	InChI=1S/C16H15N3O3S/c1-11-12(2)18-22-16(11)19-23(20,21)15-8-4-3-7-14(15)13-6-5-9-17-10-13/h3-10,19H,1-2H3	JRBXLVCTGYNQPT-UHFFFAOYSA-N	50068708	CHEMBL148637::N-(3,4-Dimethyl-isoxazol-5-yl)-2-pyridin-3-yl-benzenesulfonamide	Endothelin-1 receptor		 260								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068708&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9797546	103962900		CHEMBL148637				ZINC00024075	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788290	Cc1noc(NS(=O)(=O)c2ccccc2-c2cccs2)c1C	InChI=1S/C15H14N2O3S2/c1-10-11(2)16-20-15(10)17-22(18,19)14-8-4-3-6-12(14)13-7-5-9-21-13/h3-9,17H,1-2H3	SKJUIECMMRBDLX-UHFFFAOYSA-N	50068712	CHEMBL357789::N-(3,4-Dimethyl-isoxazol-5-yl)-2-thiophen-2-yl-benzenesulfonamide	Endothelin-1 receptor		 950								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068712&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9927658	103962904		CHEMBL357789				ZINC00007718	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788306	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccsc2)c1C	InChI=1S/C15H14N2O3S2/c1-10-11(2)16-20-15(10)17-22(18,19)14-6-4-3-5-13(14)12-7-8-21-9-12/h3-9,17H,1-2H3	JNWRGPHBQUMQGS-UHFFFAOYSA-N	50068718	CHEMBL151819::N-(3,4-Dimethyl-isoxazol-5-yl)-2-thiophen-3-yl-benzenesulfonamide	Endothelin-1 receptor		 900								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068718&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9840650	103962910		CHEMBL151819				ZINC00024072	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788335	Cc1noc(NS(=O)(=O)c2ccccc2-c2ncccn2)c1C	InChI=1S/C15H14N4O3S/c1-10-11(2)18-22-15(10)19-23(20,21)13-7-4-3-6-12(13)14-16-8-5-9-17-14/h3-9,19H,1-2H3	OFRKUESHXBIBCU-UHFFFAOYSA-N	50068737	CHEMBL357678::N-(3,4-Dimethyl-isoxazol-5-yl)-2-pyrimidin-2-yl-benzenesulfonamide	Endothelin-1 receptor		 8800								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068737&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9818889	103962929		CHEMBL357678				ZINC00024074	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50788371	Cc1noc(NS(=O)(=O)c2ccccc2-c2c[nH]c3ccccc23)c1C	InChI=1S/C19H17N3O3S/c1-12-13(2)21-25-19(12)22-26(23,24)18-10-6-4-8-15(18)16-11-20-17-9-5-3-7-14(16)17/h3-11,20,22H,1-2H3	PUAMCBIYRNRGBC-UHFFFAOYSA-N	50068679	CHEMBL357331::N-(3,4-Dimethyl-isoxazol-5-yl)-2-(1H-indol-3-yl)-benzenesulfonamide	Endothelin-1 receptor		 520								ChEMBL	10.1021/jm970872k	10.7270/Q2J9672R	9857090			Murugesan, N; Gu, Z; Stein, PD; Bisaha, S; Spergel, S; Girotra, R; Lee, VG; Lloyd, J; Misra, RN; Schmidt, J; Mathur, A; Stratton, L; Kelly, YF; Bird, E; Waldron, T; Liu, EC; Zhang, R; Lee, H; Serafino, R; Abboa-Offei, B; Mathers, P; Giancarli, M; Seymour, AA; Webb, ML; Hunt, JT	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068679&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9799352	103962871		CHEMBL357331				ZINC03923829	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50802621	Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C27H28BrN5O4S/c1-18-5-7-19(8-6-18)23-24(33-38(34,35)22-11-9-20(10-12-22)27(2,3)4)31-17-32-25(23)36-13-14-37-26-29-15-21(28)16-30-26/h5-12,15-17H,13-14H2,1-4H3,(H,31,32,33)	XCDYCRJUBJSYLD-UHFFFAOYSA-N	50105033	CHEMBL112531::N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-4-tert-butyl-benzenesulfonamide	Endothelin-1 receptor		 0.00420								ChEMBL	10.1021/jm000538f	10.7270/Q27M08P8	11585442			Morimoto, H; Ohashi, N; Shimadzu, H; Kushiyama, E; Kawanishi, H; Hosaka, T; Kawase, Y; Yasuda, K; Kikkawa, K; Yamauchi-Kohno, R; Yamada, K	Tanabe Seiyaku Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105033&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9938571	104000830		CHEMBL112531				ZINC01542085	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50802624	COc1ccccc1Oc1c([N-]S(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H28N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3/q-1	UJGUMHQLVYROSG-UHFFFAOYSA-N	50105000	CHEMBL175616::sodium salt of 4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-benzenesulfonamide	Endothelin-1 receptor		 81								ChEMBL	10.1021/jm000538f	10.7270/Q27M08P8	11585442			Morimoto, H; Ohashi, N; Shimadzu, H; Kushiyama, E; Kawanishi, H; Hosaka, T; Kawase, Y; Yasuda, K; Kikkawa, K; Yamauchi-Kohno, R; Yamada, K	Tanabe Seiyaku Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105000&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91931778	104000797		CHEMBL175616				ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50802638	Cc1ccc(cc1)-c1c([N-]S(=O)(=O)c2ccc(cc2)C(C)(C)CO)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C27H27BrN5O5S/c1-18-4-6-19(7-5-18)23-24(33-39(35,36)22-10-8-20(9-11-22)27(2,3)16-34)31-17-32-25(23)37-12-13-38-26-29-14-21(28)15-30-26/h4-11,14-15,17,34H,12-13,16H2,1-3H3/q-1	VYAFCUPPLXQIIN-UHFFFAOYSA-N	50369953	CHEMBL1627022	Endothelin-1 receptor		 0.015								ChEMBL	10.1021/jm000538f	10.7270/Q27M08P8	11585442			Morimoto, H; Ohashi, N; Shimadzu, H; Kushiyama, E; Kawanishi, H; Hosaka, T; Kawase, Y; Yasuda, K; Kikkawa, K; Yamauchi-Kohno, R; Yamada, K	Tanabe Seiyaku Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369953&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91930365	160849055		CHEMBL1627022				ZINC08576535	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811253	CC(C)N(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(C)=O	InChI=1S/C26H28N4O5S/c1-16(2)30(19(5)31)15-21-14-20(26-27-12-13-34-26)10-11-22(21)23-8-6-7-9-24(23)36(32,33)29-25-17(3)18(4)28-35-25/h6-14,16,29H,15H2,1-5H3	JXDROKHYBYCLBZ-UHFFFAOYSA-N	50122679	CHEMBL29775::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-isopropyl-acetamide	Endothelin-1 receptor		 0.4								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122679&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10864118	104015319		CHEMBL29775				ZINC13492863	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811254	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CNCC(F)(F)F)-c2ncco2)c1C	InChI=1S/C23H21F3N4O4S/c1-14-15(2)29-34-21(14)30-35(31,32)20-6-4-3-5-19(20)18-8-7-16(22-28-9-10-33-22)11-17(18)12-27-13-23(24,25)26/h3-11,27,30H,12-13H2,1-2H3	ZHRNJYRTUCXIIO-UHFFFAOYSA-N	50122677	4'-Oxazol-2-yl-2'-[(2,2,2-trifluoro-ethylamino)-methyl]-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29420	Endothelin-1 receptor		 0.8								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122677&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10973218	104015317		CHEMBL29420				ZINC13492876	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811255	CN(C(=O)CC(C)(C)C)c1cc(ccc1-c1ccccc1S(=O)(=O)Nc1noc(C)c1C)-c1ncco1	InChI=1S/C27H30N4O5S/c1-17-18(2)36-29-25(17)30-37(33,34)23-10-8-7-9-21(23)20-12-11-19(26-28-13-14-35-26)15-22(20)31(6)24(32)16-27(3,4)5/h7-15H,16H2,1-6H3,(H,29,30)	AXFKGEZDVMCYEO-UHFFFAOYSA-N	50122676	CHEMBL274489::N-[2'-(4,5-Dimethyl-isoxazol-3-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-3,3,N-trimethyl-butyramide	Endothelin-1 receptor		 0.01								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122676&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44277840	104015316		CHEMBL274489				ZINC28768521	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811256	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2Cn2cccn2)-c2ncco2)c1C	InChI=1S/C24H21N5O4S/c1-16-17(2)27-33-23(16)28-34(30,31)22-7-4-3-6-21(22)20-9-8-18(24-25-11-13-32-24)14-19(20)15-29-12-5-10-26-29/h3-14,28H,15H2,1-2H3	ZJLHLNFPEQWJRL-UHFFFAOYSA-N	50122680	4'-Oxazol-2-yl-2'-pyrazol-1-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL30092	Endothelin-1 receptor		 0.3								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122680&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11730445	104015320		CHEMBL30092				ZINC13492881	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811257	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-26-20/h3-12,23H,1-2H3	LJGUZUROJOJEMI-UHFFFAOYSA-N	50091105	4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide::BMS-193884::CHEMBL24461	Endothelin-1 receptor		 1.4								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9843631	103989493		CHEMBL24461				ZINC00836695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811262	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CN2CC(C)(C)CC2=O)-c2ncco2)c1C	InChI=1S/C27H28N4O5S/c1-17-18(2)29-36-25(17)30-37(33,34)23-8-6-5-7-22(23)21-10-9-19(26-28-11-12-35-26)13-20(21)15-31-16-27(3,4)14-24(31)32/h5-13,30H,14-16H2,1-4H3	XVGVBINHYILTRX-UHFFFAOYSA-N	50122684	2'-(4,4-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL30405	Endothelin-1 receptor		 0.045								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122684&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10918368	104015324		CHEMBL30405				ZINC13492867	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811263	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2COc2ccccc2)-c2ncco2)c1C	InChI=1S/C27H23N3O5S/c1-18-19(2)29-35-26(18)30-36(31,32)25-11-7-6-10-24(25)23-13-12-20(27-28-14-15-33-27)16-21(23)17-34-22-8-4-3-5-9-22/h3-16,30H,17H2,1-2H3	UEBNKNPUEAOWHJ-UHFFFAOYSA-N	50122683	4'-Oxazol-2-yl-2'-phenoxymethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL28586	Endothelin-1 receptor		 1								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122683&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11103112	104015323		CHEMBL28586				ZINC13492873	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811266	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2Cc2ncco2)-c2ncco2)c1C	InChI=1S/C24H20N4O5S/c1-15-16(2)27-33-23(15)28-34(29,30)21-6-4-3-5-20(21)19-8-7-17(24-26-10-12-32-24)13-18(19)14-22-25-9-11-31-22/h3-13,28H,14H2,1-2H3	QSDFLNIZMIGXOO-UHFFFAOYSA-N	50122687	4'-Oxazol-2-yl-2'-oxazol-2-ylmethyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29598	Endothelin-1 receptor		 0.75								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122687&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11081276	104015327		CHEMBL29598				ZINC13492880	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811271	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)c1cc2ccccc2n1C	InChI=1S/C32H29N5O5S/c1-20-21(2)34-42-30(20)35-43(39,40)29-12-8-6-10-26(29)25-14-13-23(31-33-15-16-41-31)17-24(25)19-36(3)32(38)28-18-22-9-5-7-11-27(22)37(28)4/h5-18,35H,19H2,1-4H3	AOOKNPITEDSSNB-UHFFFAOYSA-N	50122686	1-Methyl-1H-indole-2-carboxylic acid [2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-methyl-amide::CHEMBL281977	Endothelin-1 receptor		 0.005								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122686&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11124821	104015326		CHEMBL281977				ZINC28767796	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811273	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)CCc1ccccc1	InChI=1S/C31H30N4O5S/c1-21-22(2)33-40-30(21)34-41(37,38)28-12-8-7-11-27(28)26-15-14-24(31-32-17-18-39-31)19-25(26)20-35(3)29(36)16-13-23-9-5-4-6-10-23/h4-12,14-15,17-19,34H,13,16,20H2,1-3H3	CMRIQBLOCJBMQY-UHFFFAOYSA-N	50122693	CHEMBL29346::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-3-phenyl-propionamide	Endothelin-1 receptor		 0.004								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122693&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10984658	104015333		CHEMBL29346				ZINC28768328	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811275	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CN2CCCC(C)(C)C2=O)-c2ncco2)c1C	InChI=1S/C28H30N4O5S/c1-18-19(2)30-37-25(18)31-38(34,35)24-9-6-5-8-23(24)22-11-10-20(26-29-13-15-36-26)16-21(22)17-32-14-7-12-28(3,4)27(32)33/h5-6,8-11,13,15-16,31H,7,12,14,17H2,1-4H3	FPJPMEXULUCUCB-UHFFFAOYSA-N	50122689	2'-(3,3-Dimethyl-2-oxo-piperidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL283610	Endothelin-1 receptor		 0.39								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122689&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11082049	104015329		CHEMBL283610				ZINC28768638	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811279	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)Cc1ccc(cc1)C(F)(F)F	InChI=1S/C31H27F3N4O5S/c1-19-20(2)36-43-29(19)37-44(40,41)27-7-5-4-6-26(27)25-13-10-22(30-35-14-15-42-30)17-23(25)18-38(3)28(39)16-21-8-11-24(12-9-21)31(32,33)34/h4-15,17,37H,16,18H2,1-3H3	UIXIDUJBKFHBRP-UHFFFAOYSA-N	50122692	CHEMBL282336::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-2-(4-trifluoromethyl-phenyl)-acetamide	Endothelin-1 receptor		 0.001								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122692&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10941181	104015332		CHEMBL282336				ZINC28768153	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811280	CC(C)C(=O)N(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C1CC1	InChI=1S/C28H30N4O5S/c1-17(2)28(33)32(22-10-11-22)16-21-15-20(27-29-13-14-36-27)9-12-23(21)24-7-5-6-8-25(24)38(34,35)31-26-18(3)19(4)30-37-26/h5-9,12-15,17,22,31H,10-11,16H2,1-4H3	XPPNYNZMOQSBAA-UHFFFAOYSA-N	50122690	CHEMBL28963::N-Cyclopropyl-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-isobutyramide	Endothelin-1 receptor		 0.05								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122690&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10929533	104015330		CHEMBL28963				ZINC28767662	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811281	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)c1ccccc1	InChI=1S/C28H26N4O4S/c1-19-20(2)30-36-27(19)31-37(33,34)26-12-8-7-11-25(26)24-14-13-21(28-29-15-16-35-28)17-22(24)18-32(3)23-9-5-4-6-10-23/h4-17,31H,18H2,1-3H3	HKMVKDPUVNFFAO-UHFFFAOYSA-N	50122697	2'-[(Methyl-phenyl-amino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29793	Endothelin-1 receptor		 0.02								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122697&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10918301	104015337		CHEMBL29793				ZINC13492875	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811286	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2Cn2ccnc2)-c2ncco2)c1C	InChI=1S/C24H21N5O4S/c1-16-17(2)27-33-23(16)28-34(30,31)22-6-4-3-5-21(22)20-8-7-18(24-26-10-12-32-24)13-19(20)14-29-11-9-25-15-29/h3-13,15,28H,14H2,1-2H3	KAIWKTKPOCNWMM-UHFFFAOYSA-N	50122699	2'-Imidazol-1-ylmethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL30009	Endothelin-1 receptor		 0.3								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122699&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11123603	104015339		CHEMBL30009				ZINC13492882	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811287	CC(=O)NCc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C23H22N4O5S/c1-14-15(2)26-32-22(14)27-33(29,30)21-7-5-4-6-20(21)19-9-8-17(23-24-10-11-31-23)12-18(19)13-25-16(3)28/h4-12,27H,13H2,1-3H3,(H,25,28)	XAHBFCGXCQNZHI-UHFFFAOYSA-N	50091104	CHEMBL29422::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-acetamide	Endothelin-1 receptor		 0.2								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091104&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11754273	103989492		CHEMBL29422				ZINC13492861	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811289	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)Cc1ccccn1	InChI=1S/C29H27N5O5S/c1-19-20(2)32-39-28(19)33-40(36,37)26-10-5-4-9-25(26)24-12-11-21(29-31-14-15-38-29)16-22(24)18-34(3)27(35)17-23-8-6-7-13-30-23/h4-16,33H,17-18H2,1-3H3	YRQIVEIVRAWSIB-UHFFFAOYSA-N	50122695	CHEMBL29710::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-2-pyridin-2-yl-acetamide	Endothelin-1 receptor		 0.6								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122695&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11124545	104015335		CHEMBL29710				ZINC28767744	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811290	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)C(C)(C)C	InChI=1S/C27H30N4O5S/c1-17-18(2)29-36-24(17)30-37(33,34)23-10-8-7-9-22(23)21-12-11-19(25-28-13-14-35-25)15-20(21)16-31(6)26(32)27(3,4)5/h7-15,30H,16H2,1-6H3	QXJMSZDXBBMLGU-UHFFFAOYSA-N	50122681	CHEMBL27855::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-2,2,N-trimethyl-propionamide	Endothelin-1 receptor		 0.03								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122681&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11731054	104015321		CHEMBL27855				ZINC13492865	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811292	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor		 8								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811294	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2\C=C\c2ccccc2)-c2ncco2)c1C	InChI=1S/C28H23N3O4S/c1-19-20(2)30-35-27(19)31-36(32,33)26-11-7-6-10-25(26)24-15-14-23(28-29-16-17-34-28)18-22(24)13-12-21-8-4-3-5-9-21/h3-18,31H,1-2H3/b13-12+	UNZAVPNCBSRDCV-OUKQBFOZSA-N	50122701	4'-Oxazol-2-yl-2'-styryl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL286279	Endothelin-1 receptor		 2.5								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122701&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11049336	104015341		CHEMBL286279				ZINC01895377	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811295	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)CC(F)(F)F	InChI=1S/C24H23F3N4O4S/c1-15-16(2)29-35-22(15)30-36(32,33)21-7-5-4-6-20(21)19-9-8-17(23-28-10-11-34-23)12-18(19)13-31(3)14-24(25,26)27/h4-12,30H,13-14H2,1-3H3	CLLGOUWASYEJSI-UHFFFAOYSA-N	50122704	2'-{[Methyl-(2,2,2-trifluoro-ethyl)-amino]-methyl}-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL431296	Endothelin-1 receptor		 0.15								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122704&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11103326	104015344		CHEMBL431296				ZINC13492877	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811296	Cc1cc(NCc2cc(ccc2-c2ccccc2S(=O)(=O)Nc2onc(C)c2C)-c2ncco2)no1	InChI=1S/C25H23N5O5S/c1-15-12-23(29-34-15)27-14-19-13-18(25-26-10-11-33-25)8-9-20(19)21-6-4-5-7-22(21)36(31,32)30-24-16(2)17(3)28-35-24/h4-13,30H,14H2,1-3H3,(H,27,29)	FAXAQTJCDNWXMJ-UHFFFAOYSA-N	50122703	2'-[(5-Methyl-isoxazol-3-ylamino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29223	Endothelin-1 receptor		 0.07								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122703&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11762890	104015343		CHEMBL29223				ZINC13492879	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811299	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)CC1CCCCC1	InChI=1S/C30H34N4O5S/c1-20-21(2)32-39-29(20)33-40(36,37)27-12-8-7-11-26(27)25-14-13-23(30-31-15-16-38-30)18-24(25)19-34(3)28(35)17-22-9-5-4-6-10-22/h7-8,11-16,18,22,33H,4-6,9-10,17,19H2,1-3H3	XFVRGRHYQOBYLX-UHFFFAOYSA-N	50122705	2-Cyclohexyl-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-acetamide::CHEMBL29652	Endothelin-1 receptor		 0.440								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122705&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11734435	104015345		CHEMBL29652				ZINC28768338	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811304	CC(C)COCc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C25H27N3O5S/c1-16(2)14-31-15-20-13-19(25-26-11-12-32-25)9-10-21(20)22-7-5-6-8-23(22)34(29,30)28-24-17(3)18(4)27-33-24/h5-13,16,28H,14-15H2,1-4H3	PMKLMFUQSSVLTH-UHFFFAOYSA-N	50122678	2'-Isobutoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL282303	Endothelin-1 receptor		 0.2								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122678&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11059912	104015318		CHEMBL282303				ZINC13492872	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811306	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2Cn2ccc(n2)C(F)(F)F)-c2ncco2)c1C	InChI=1S/C25H20F3N5O4S/c1-15-16(2)31-37-23(15)32-38(34,35)21-6-4-3-5-20(21)19-8-7-17(24-29-10-12-36-24)13-18(19)14-33-11-9-22(30-33)25(26,27)28/h3-13,32H,14H2,1-2H3	XUNPAGDDNXAXMC-UHFFFAOYSA-N	50122700	4'-Oxazol-2-yl-2'-(3-trifluoromethyl-pyrazol-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL285832	Endothelin-1 receptor		 0.02								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122700&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11124425	104015340		CHEMBL285832				ZINC28767496	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811307	CC(C)N(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)C(C)(C)C	InChI=1S/C29H34N4O5S/c1-18(2)33(28(34)29(5,6)7)17-22-16-21(27-30-14-15-37-27)12-13-23(22)24-10-8-9-11-25(24)39(35,36)32-26-19(3)20(4)31-38-26/h8-16,18,32H,17H2,1-7H3	DIUGGNHRGFFKOH-UHFFFAOYSA-N	50122691	CHEMBL29502::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-isopropyl-2,2-dimethyl-propionamide	Endothelin-1 receptor		 6								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122691&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11006149	104015331		CHEMBL29502				ZINC28767536	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811310	CN(C)C(=O)Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C24H24N4O5S/c1-15-16(2)26-33-23(15)27-34(30,31)21-8-6-5-7-20(21)19-10-9-17(24-25-11-12-32-24)13-18(19)14-22(29)28(3)4/h5-13,27H,14H2,1-4H3	LZJBWBJQATUAPH-UHFFFAOYSA-N	50122709	2-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-N,N-dimethyl-acetamide::CHEMBL281668	Endothelin-1 receptor		 1								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122709&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11733544	104015349		CHEMBL281668				ZINC13492869	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811311	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)CC(C)(C)C	InChI=1S/C28H32N4O5S/c1-18-19(2)30-37-26(18)31-38(34,35)24-10-8-7-9-23(24)22-12-11-20(27-29-13-14-36-27)15-21(22)17-32(6)25(33)16-28(3,4)5/h7-15,31H,16-17H2,1-6H3	QDKJEEQYGZGXKJ-UHFFFAOYSA-N	50122707	CHEMBL281659::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-3,3,N-trimethyl-butyramide	Endothelin-1 receptor		 0.02								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122707&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10119517	104015347		CHEMBL281659				ZINC28767439	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811312	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CN2CCC(C)(C)C2=O)-c2ncco2)c1C	InChI=1S/C27H28N4O5S/c1-17-18(2)29-36-24(17)30-37(33,34)23-8-6-5-7-22(23)21-10-9-19(25-28-12-14-35-25)15-20(21)16-31-13-11-27(3,4)26(31)32/h5-10,12,14-15,30H,11,13,16H2,1-4H3	XPBBDUYWSIZCNR-UHFFFAOYSA-N	50122694	2'-(3,3-Dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29972	Endothelin-1 receptor		 0.005								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122694&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11145758	104015334		CHEMBL29972				ZINC13492866	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811313	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(C)=O	InChI=1S/C24H24N4O5S/c1-15-16(2)26-33-23(15)27-34(30,31)22-8-6-5-7-21(22)20-10-9-18(24-25-11-12-32-24)13-19(20)14-28(4)17(3)29/h5-13,27H,14H2,1-4H3	WOBBXUGAQYJTDY-UHFFFAOYSA-N	50122710	CHEMBL284656::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-acetamide	Endothelin-1 receptor		 0.2								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122710&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10972867	104015350		CHEMBL284656				ZINC13492862	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811314	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)CC(F)(F)F	InChI=1S/C25H23F3N4O5S/c1-15-16(2)30-37-23(15)31-38(34,35)21-7-5-4-6-20(21)19-9-8-17(24-29-10-11-36-24)12-18(19)14-32(3)22(33)13-25(26,27)28/h4-12,31H,13-14H2,1-3H3	TWNPZFARHUKPBV-UHFFFAOYSA-N	50122696	CHEMBL281549::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-3,3,3-trifluoro-N-methyl-propionamide	Endothelin-1 receptor		 0.05								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122696&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11082168	104015336		CHEMBL281549				ZINC28767971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811315	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)c1cc(Cl)cc(Cl)c1	InChI=1S/C29H24Cl2N4O5S/c1-17-18(2)33-40-27(17)34-41(37,38)26-7-5-4-6-25(26)24-9-8-19(28-32-10-11-39-28)12-21(24)16-35(3)29(36)20-13-22(30)15-23(31)14-20/h4-15,34H,16H2,1-3H3	LNPRLVTXUXFAEN-UHFFFAOYSA-N	50122715	3,5-Dichloro-N-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-benzamide::CHEMBL30150	Endothelin-1 receptor		 0.0090								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122715&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10941084	104015355		CHEMBL30150				ZINC28768155	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811316	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CC(=O)NC(C)(C)C)-c2ncco2)c1C	InChI=1S/C26H28N4O5S/c1-16-17(2)29-35-24(16)30-36(32,33)22-9-7-6-8-21(22)20-11-10-18(25-27-12-13-34-25)14-19(20)15-23(31)28-26(3,4)5/h6-14,30H,15H2,1-5H3,(H,28,31)	IYEPVPVXSCCBFG-UHFFFAOYSA-N	50122702	CHEMBL30215::N-tert-Butyl-2-[2'-(3,4-dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-acetamide	Endothelin-1 receptor		 0.6								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122702&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10907333	104015342		CHEMBL30215				ZINC13492870	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811321	CN1CCN(Cc2cc(ccc2-c2ccccc2S(=O)(=O)Nc2onc(C)c2C)-c2ncco2)C1=O	InChI=1S/C25H25N5O5S/c1-16-17(2)27-35-23(16)28-36(32,33)22-7-5-4-6-21(22)20-9-8-18(24-26-10-13-34-24)14-19(20)15-30-12-11-29(3)25(30)31/h4-10,13-14,28H,11-12,15H2,1-3H3	CTSLPVTWRWISJE-UHFFFAOYSA-N	50122706	2'-(3-Methyl-2-oxo-imidazolidin-1-ylmethyl)-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL282628	Endothelin-1 receptor		 0.004								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122706&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11103181	104015346		CHEMBL282628				ZINC13492868	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811322	CC(C)C(=O)N(C)Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C26H28N4O5S/c1-16(2)26(31)30(5)15-20-14-19(25-27-12-13-34-25)10-11-21(20)22-8-6-7-9-23(22)36(32,33)29-24-17(3)18(4)28-35-24/h6-14,16,29H,15H2,1-5H3	QGMUOSXKQHPOGD-UHFFFAOYSA-N	50122698	CHEMBL28863::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-isobutyramide	Endothelin-1 receptor		 0.04								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122698&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11027595	104015338		CHEMBL28863				ZINC13492864	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811323	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CNc2ccncn2)-c2ncco2)c1C	InChI=1S/C25H22N6O4S/c1-16-17(2)30-35-24(16)31-36(32,33)22-6-4-3-5-21(22)20-8-7-18(25-27-11-12-34-25)13-19(20)14-28-23-9-10-26-15-29-23/h3-13,15,31H,14H2,1-2H3,(H,26,28,29)	VHHUBYWYNJXLPT-UHFFFAOYSA-N	50122711	4'-Oxazol-2-yl-2'-(pyrimidin-4-ylaminomethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29464	Endothelin-1 receptor		 0.15								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122711&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10973161	104015351		CHEMBL29464				ZINC13492878	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811324	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2\C=C/c2ccccc2)-c2ncco2)c1C	InChI=1S/C28H23N3O4S/c1-19-20(2)30-35-27(19)31-36(32,33)26-11-7-6-10-25(26)24-15-14-23(28-29-16-17-34-28)18-22(24)13-12-21-8-4-3-5-9-21/h3-18,31H,1-2H3/b13-12-	UNZAVPNCBSRDCV-SEYXRHQNSA-N	50122682	4'-Oxazol-2-yl-2'-styryl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL29313	Endothelin-1 receptor		 1.5								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122682&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11113812	104015322		CHEMBL29313				ZINC80849287	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811326	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)c1ccccc1	InChI=1S/C29H26N4O5S/c1-19-20(2)31-38-27(19)32-39(35,36)26-12-8-7-11-25(26)24-14-13-22(28-30-15-16-37-28)17-23(24)18-33(3)29(34)21-9-5-4-6-10-21/h4-17,32H,18H2,1-3H3	KMOYVJSVLLXFQU-UHFFFAOYSA-N	50122713	CHEMBL282359::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-benzamide	Endothelin-1 receptor		 0.04								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122713&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11813553	104015353		CHEMBL282359				ZINC01485144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811330	CC(C)OCc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C24H25N3O5S/c1-15(2)31-14-19-13-18(24-25-11-12-30-24)9-10-20(19)21-7-5-6-8-22(21)33(28,29)27-23-16(3)17(4)26-32-23/h5-13,15,27H,14H2,1-4H3	XJUXAAFCMXUBET-UHFFFAOYSA-N	50122708	2'-Isopropoxymethyl-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL285118	Endothelin-1 receptor		 0.6								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122708&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11812665	104015348		CHEMBL285118				ZINC13492871	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811331	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1)C(=O)Cc1ccccc1	InChI=1S/C30H28N4O5S/c1-20-21(2)32-39-29(20)33-40(36,37)27-12-8-7-11-26(27)25-14-13-23(30-31-15-16-38-30)18-24(25)19-34(3)28(35)17-22-9-5-4-6-10-22/h4-16,18,33H,17,19H2,1-3H3	CJGRNBWHDOSFES-UHFFFAOYSA-N	50122712	CHEMBL440780::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-N-methyl-2-phenyl-acetamide	Endothelin-1 receptor		 0.01								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122712&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11071765	104015352		CHEMBL440780				ZINC28767814	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50811332	CC(C)CN(C)Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)-c1ncco1	InChI=1S/C26H30N4O4S/c1-17(2)15-30(5)16-21-14-20(26-27-12-13-33-26)10-11-22(21)23-8-6-7-9-24(23)35(31,32)29-25-18(3)19(4)28-34-25/h6-14,17,29H,15-16H2,1-5H3	KFYGWINTMGEMTO-UHFFFAOYSA-N	50122714	2'-[(Isobutyl-methyl-amino)-methyl]-4'-oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL281869	Endothelin-1 receptor		 8.5								ChEMBL	10.1021/jm020289q	10.7270/Q2348M3R	12502366			Murugesan, N; Gu, Z; Spergel, S; Young, M; Chen, P; Mathur, A; Leith, L; Hermsmeier, M; Liu, EC; Zhang, R; Bird, E; Waldron, T; Marino, A; Koplowitz, B; Humphreys, WG; Chong, S; Morrison, RA; Webb, ML; Moreland, S; Trippodo, N; Barrish, JC	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122714&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11071062	104015354		CHEMBL281869				ZINC13492874	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50794859	COc1ccc(CC2C(C(=O)O[C@@]2(O)c2ccc(OC)cc2)c2ccc(Cl)c(Cl)c2)cc1	InChI=1S/C25H22Cl2O5/c1-30-18-8-3-15(4-9-18)13-20-23(16-5-12-21(26)22(27)14-16)24(28)32-25(20,29)17-6-10-19(31-2)11-7-17/h3-12,14,20,23,29H,13H2,1-2H3/t20?,23?,25-/m0/s1	WVJKUKCCKMNTKW-QNAFOZIXSA-N	50088241	3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methoxy-benzyl)-5-(4-methoxy-phenyl)-dihydro-furan-2-one::CHEMBL64424	Endothelin-1 receptor		 170								ChEMBL	10.1021/jm990504b	10.7270/Q2MP53ZS	10821712			Wintner, EA; Moallemi, CC	NeoGenesis, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088241&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44303033	103987181		CHEMBL64424				ZINC26166120	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50794862	O[C@]1(OC(=O)C(C1Cc1ccccc1)c1ccc2OCOc2c1)c1ccc(Cl)c(Cl)c1	InChI=1S/C24H18Cl2O5/c25-18-8-7-16(12-19(18)26)24(28)17(10-14-4-2-1-3-5-14)22(23(27)31-24)15-6-9-20-21(11-15)30-13-29-20/h1-9,11-12,17,22,28H,10,13H2/t17?,22?,24-/m0/s1	XIKUSXQTILEQON-HRCMYCDISA-N	50088243	3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dichloro-phenyl)-5-hydroxy-dihydro-furan-2-one::CHEMBL64200	Endothelin-1 receptor		 400								ChEMBL	10.1021/jm990504b	10.7270/Q2MP53ZS	10821712			Wintner, EA; Moallemi, CC	NeoGenesis, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088243&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44303148	103987183		CHEMBL64200				ZINC26163045	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50820856	Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2cc3OCOc3cc2C)c1Cl	InChI=1S/C18H15ClN2O6S2/c1-9-5-13-14(26-8-25-13)7-11(9)6-12(22)17-15(3-4-28-17)29(23,24)21-18-16(19)10(2)20-27-18/h3-5,7,21H,6,8H2,1-2H3	PHWXUGHIIBDVKD-UHFFFAOYSA-N	50058126	2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide::2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thiophene-3-sulfonic acid (4-chloro-3-methyl-isoxazol-5-yl)-amide (Sitaxsentan)::2-{[3-(4-Chloro-3-methyl-isoxazol-5-ylsulfamoyl)-thiophene-2-carbonyl]-amino}-5-methyl-benzoic acid isopropyl ester::CHEMBL282724::Sitaxentan	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm030528p	10.7270/Q2HD7WD6	15055997			Wu, C; Decker, ER; Blok, N; Bui, H; You, TJ; Wang, J; Bourgoyne, AR; Knowles, V; Berens, KL; Holland, GW; Brock, TA; Dixon, RA	Encysive Pharmaceuticals Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50058126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50058126&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			216235	103954105		CHEMBL282724	DB06268	3950		ZINC01481831	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50833609	CN(Cc1cc(ccc1-c1ccccc1S(=O)(=O)Nc1noc(C)c1C)-c1ncco1)C(=O)CC(C)(C)C	InChI=1S/C28H32N4O5S/c1-18-19(2)37-30-26(18)31-38(34,35)24-10-8-7-9-23(24)22-12-11-20(27-29-13-14-36-27)15-21(22)17-32(6)25(33)16-28(3,4)5/h7-15H,16-17H2,1-6H3,(H,30,31)	ORJRYNKVKJAJPY-UHFFFAOYSA-N	50175502	CHEMBL383581::N-[2'-(4,5-Dimethyl-isoxazol-3-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-3,3,N-trimethyl-butyramide	Endothelin-1 receptor		 10								ChEMBL	10.1021/jm058225d	10.7270/Q2SF2WZ9	16220969			Morphy, R; Rankovic, Z	Organon Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175502&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			156690	104061195		CHEMBL383581				ZINC01481808	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50833655	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2CCOc2c1	InChI=1S/C39H44N4O5S/c1-7-9-30-21-27(23-43-35(8-2)41-36-25(5)20-26(6)40-38(36)43)10-17-33(30)48-37(31-12-11-29-18-19-47-34(29)22-31)39(44)42-49(45,46)32-15-13-28(14-16-32)24(3)4/h10-17,20-22,24,37H,7-9,18-19,23H2,1-6H3,(H,42,44)	WQLXYQSKSGEIPU-UHFFFAOYSA-N	50175506	CHEMBL372814::N-{2-(2,3-Dihydro-benzofuran-6-yl)-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 24							ChEMBL	10.1021/jm058225d	10.7270/Q2SF2WZ9	16220969			Morphy, R; Rankovic, Z	Organon Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175506&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44404967	104061199		CHEMBL372814				ZINC28528766	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50833719	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C36H45N5O5S/c1-6-7-14-31-37-36(17-10-11-18-36)34(43)41(31)22-26-15-16-28(27(21-26)23-40-20-19-35(4,5)33(40)42)29-12-8-9-13-30(29)47(44,45)39-32-24(2)25(3)38-46-32/h8-9,12-13,15-16,21,39H,6-7,10-11,14,17-20,22-23H2,1-5H3	NBDFXMDYBLSGLX-UHFFFAOYSA-N	50117910	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2''-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2'-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::BMS-248360::CHEMBL11706	Endothelin-1 receptor		 1.9								ChEMBL	10.1021/jm058225d	10.7270/Q2SF2WZ9	16220969			Morphy, R; Rankovic, Z	Organon Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117910&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895957	104011318		CHEMBL11706				ZINC26026608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50833723	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(COCC)c1)-c1ccccc1S(=O)(=O)Nc1noc(C)c1C	InChI=1S/C32H40N4O5S/c1-5-7-14-29-33-32(17-10-11-18-32)31(37)36(29)20-24-15-16-26(25(19-24)21-40-6-2)27-12-8-9-13-28(27)42(38,39)35-30-22(3)23(4)41-34-30/h8-9,12-13,15-16,19H,5-7,10-11,14,17-18,20-21H2,1-4H3,(H,34,35)	WRFHGDPIDHPWIQ-UHFFFAOYSA-N	50175523	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2''-ethoxymethyl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2'-ethoxymethyl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide::CHEMBL539423	Endothelin-1 receptor		 9.3								ChEMBL	10.1021/jm058225d	10.7270/Q2SF2WZ9	16220969			Morphy, R; Rankovic, Z	Organon Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175523&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10257882	104061216		CHEMBL539423				ZINC28116760	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50833730	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1	InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)	YOSHYTLCDANDAN-UHFFFAOYSA-N	50042235	2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::BMS 186295::CHEMBL1513::IRBESARTAN	Endothelin-1 receptor		>10000								ChEMBL	10.1021/jm058225d	10.7270/Q2SF2WZ9	16220969			Morphy, R; Rankovic, Z	Organon Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3749	103973843		CHEMBL1513		589	C07469	ZINC13298436	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50833748	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1cc(Br)c(OC)c(OC)c1Br	InChI=1S/C33H39Br2N3O5/c1-8-11-21-14-20(17-38-25(10-3)37-27-18(4)13-19(5)36-32(27)38)15-22(12-9-2)28(21)43-29(33(39)40)23-16-24(34)30(41-6)31(42-7)26(23)35/h13-16,29H,8-12,17H2,1-7H3,(H,39,40)	FJMSQNXGEWIXSJ-UHFFFAOYSA-N	50175515	(2,5-Dibromo-3,4-dimethoxy-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2,6-dipropyl-phenoxy]-acetic acid::CHEMBL276819	Endothelin-1 receptor			 11000							ChEMBL	10.1021/jm058225d	10.7270/Q2SF2WZ9	16220969			Morphy, R; Rankovic, Z	Organon Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175515&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19385674	104061208		CHEMBL276819				ZINC49605971	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819808	COc1cc(OC)nc(CC(C(O)=O)C(C)(Oc2ccc(SC)cc2)c2ccccc2)n1	InChI=1S/C24H26N2O5S/c1-24(16-8-6-5-7-9-16,31-17-10-12-18(32-4)13-11-17)19(23(27)28)14-20-25-21(29-2)15-22(26-20)30-3/h5-13,15,19H,14H2,1-4H3,(H,27,28)	KUCJLLMSQYNCNB-UHFFFAOYSA-N	50140750	2-(4,6-Dimethoxy-pyrimidin-2-ylmethyl)-3-(4-methylsulfanyl-phenoxy)-3-phenyl-butyric acid::CHEMBL24906	Endothelin-1 receptor		 160								ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140750&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44274885	104030301		CHEMBL24906				ZINC28758740	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819831	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2CNC(=O)CC(C)(C)C)-c2ncco2)c1C	InChI=1S/C27H30N4O5S/c1-17-18(2)30-36-25(17)31-37(33,34)23-9-7-6-8-22(23)21-11-10-19(26-28-12-13-35-26)14-20(21)16-29-24(32)15-27(3,4)5/h6-14,31H,15-16H2,1-5H3,(H,29,32)	GBHZRMWZYDRRRK-UHFFFAOYSA-N	50140757	BMS-207940::CHEMBL277447::N-[2'-(3,4-Dimethyl-isoxazol-5-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-ylmethyl]-3,3-dimethyl-butyramide	Endothelin-1 receptor		 0.010								ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140757&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44275660	104030308		CHEMBL277447				ZINC28760155	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819836	Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C	InChI=1S/C11H13N3O3S/c1-7-8(2)13-17-11(7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6,14H,12H2,1-2H3	NHUHCSRWZMLRLA-UHFFFAOYSA-N	50034452	4-Amino-N-(3,4-dimethyl-isoxazol-5-yl)-benzenesulfonamide::CHEMBL453::Eryzole::Gantrisin::Pediazole::SULFISOXAZOLE::Sosol::Soxazole::Sulfafurazole::Sulfalar::Sulfisoxazol::Sulphafurazole::Sulsoxin	Endothelin-1 receptor			 780							ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034452&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5344	103942653	102484	CHEMBL453	DB00263		C07318	ZINC96006009	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819841	COc1cc(OC)nc(OC(C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C22H22N2O6/c1-27-17-14-18(28-2)24-21(23-17)30-19(20(25)26)22(29-3,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-14,19H,1-3H3,(H,25,26)	FEJVSJIALLTFRP-UHFFFAOYSA-N	50050794	2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL25344	Endothelin-1 receptor		 6								ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050794&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9953358	103947887		CHEMBL25344				ZINC13756022	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819844	Nc1ccc(cc1)S(=O)(=O)Nc1nccs1	InChI=1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)	JNMRHUJNCSQMMB-UHFFFAOYSA-N	50027796	2-(Sulfanilylamino)thiazole::2-(p-Aminobenzenesulfonamido)thiazole::2-(p-Aminobenzenesulphonamido)thiazole::2-Sulfanilamidothiazol::2-Sulfanilamidothiazole::2-Sulfonamidothiazole::4-Amino-N-2-thiazolylbenzenesulfonamide::4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide::CHEMBL437::N(1)-2-Thiazolylsulfanilamide::Sulfanilamidothiazole::Sulfathiazole::Sulphathiazole::cid_5340	Endothelin-1 receptor			 69000							ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027796&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	YTZ	3TYE,5CP3,5G44,4J7U	5340	103937245	9337	CHEMBL437	DB06147		C11169	ZINC00121458	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819845	COc1cc(OC)nc(CC(C(O)=O)C(C)(Oc2ccc(cc2)C(C)C)c2ccccc2)n1	InChI=1S/C26H30N2O5/c1-17(2)18-11-13-20(14-12-18)33-26(3,19-9-7-6-8-10-19)21(25(29)30)15-22-27-23(31-4)16-24(28-22)32-5/h6-14,16-17,21H,15H2,1-5H3,(H,29,30)	PWSKRNZJMABAOX-UHFFFAOYSA-N	50140761	2-(4,6-Dimethoxy-pyrimidin-2-ylmethyl)-3-(4-isopropyl-phenoxy)-3-phenyl-butyric acid::CHEMBL283637	Endothelin-1 receptor		 250								ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140761&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44274960	104030310		CHEMBL283637				ZINC28757385	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819859	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-26-20/h3-12,23H,1-2H3	LJGUZUROJOJEMI-UHFFFAOYSA-N	50091105	4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide::BMS-193884::CHEMBL24461	Endothelin-1 receptor		 1.4								ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9843631	103989493		CHEMBL24461				ZINC00836695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50819903	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor			 150							ChEMBL	10.1021/jm030480f	10.7270/Q2FN16X5	14998318			Wermuth, CG	Prestwick Chemical Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50858333	COc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc(OC)c1	InChI=1S/C19H16ClNO4/c1-23-15-9-14(10-16(11-15)24-2)21-19(22)18-8-7-17(25-18)12-3-5-13(20)6-4-12/h3-11H,1-2H3,(H,21,22)	VHKBTPQDHDSBSP-UHFFFAOYSA-N	50212239	5-(4-chlorophenyl)-N-(3,5-dimethoxyphenyl)furan-2-carboxamide::A-803467::CHEMBL250699	Endothelin-1 receptor			>10000							ChEMBL	10.1073/pnas.0611364104	10.7270/Q2J10411	17483457			Jarvis, MF; Honore, P; Shieh, CC; Chapman, M; Joshi, S; Zhang, XF; Kort, M; Carroll, W; Marron, B; Atkinson, R; Thomas, J; Liu, D; Krambis, M; Liu, Y; McGaraughty, S; Chu, K; Roeloffs, R; Zhong, C; Mikusa, JP; Hernandez, G; Gauvin, D; Wade, C; Zhu, C; Pai, M; Scanio, M; Shi, L; Drizin, I; Gregg, R; Matulenko, M; Hakeem, A; Gross, M; Johnson, M; Marsh, K; Wagoner, PK; Sullivan, JP; Faltynek, CR; Krafte, DS	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212239&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	95T	7WFR,7WE4,7WEL	16038374	104088220		CHEMBL250699		5734		ZINC14982453	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50909946	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@@H](N)C(=O)N[C@H](CO)C(=O)N[C@H]2CSSC[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C109H159N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80-49-169-168-48-64(111)89(145)126-77(45-135)102(158)131-81-50-170-171-51-82(105(161)132-86(55(7)8)106(162)124-72(38-59-26-28-62(138)29-27-59)95(151)120-71(96(152)130-80)37-58-21-15-14-16-22-58)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-167-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(81)160/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64+,66-,67-,68-,69+,70-,71-,72+,73-,74+,75-,76-,77+,78-,79+,80-,81-,82+,86-,87-,88-/m0/s1	ZUBDGKVDJUIMQQ-UBFCDGJISA-N	50000558	CHEMBL437472::ET-1::Endothelin -1::Endothelin 1, ET-1::Endothelin derivative::Endothelin-1::c(Cys-Ser-c(Cys-Ser-Ser-Leu-Met-Asp-Lys-Gln-Cys)-Val-Tyr-Phe-Cys)-His-Leu-Asp-Ile-Ile-Trp	Endothelin-1 receptor			 0.047							ChEMBL	10.1021/np900287e	10.7270/Q2MC910T	19916528			Gao, J; Caballero-George, C; Wang, B; Rao, KV; Shilabin, AG; Hamann, MT	The University of Mississippi	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91928636	103915106		CHEMBL437472					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945425	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(Cn3cnc4ccccc34)cc2)c1C	InChI=1S/C25H22N4O3S/c1-17-18(2)27-32-25(17)28-33(30,31)24-10-6-3-7-21(24)20-13-11-19(12-14-20)15-29-16-26-22-8-4-5-9-23(22)29/h3-14,16,28H,15H2,1-2H3	KXEGSRYENWAYGG-UHFFFAOYSA-N	50387806	CHEMBL2058366	Endothelin-1 receptor			 99							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387806&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70686380	160866889		CHEMBL2058366				ZINC84710534	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945426	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(Cn3c(C)nc4ccccc34)cc2)c1C	InChI=1S/C26H24N4O3S/c1-17-18(2)28-33-26(17)29-34(31,32)25-11-7-4-8-22(25)21-14-12-20(13-15-21)16-30-19(3)27-23-9-5-6-10-24(23)30/h4-15,29H,16H2,1-3H3	MCGCJFJGNKEDPW-UHFFFAOYSA-N	50387807	CHEMBL2058367	Endothelin-1 receptor			 75							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387807&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70694736	160866890		CHEMBL2058367				ZINC84710536	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945427	CCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C27H26N4O3S/c1-4-26-28-23-10-6-7-11-24(23)31(26)17-20-13-15-21(16-14-20)22-9-5-8-12-25(22)35(32,33)30-27-18(2)19(3)29-34-27/h5-16,30H,4,17H2,1-3H3	QKHHIXDFXAGGQQ-UHFFFAOYSA-N	50387808	CHEMBL2058368	Endothelin-1 receptor			 39							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387808&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70686381	160866891		CHEMBL2058368				ZINC84703643	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945428	CCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C28H28N4O3S/c1-4-9-27-29-24-11-6-7-12-25(24)32(27)18-21-14-16-22(17-15-21)23-10-5-8-13-26(23)36(33,34)31-28-19(2)20(3)30-35-28/h5-8,10-17,31H,4,9,18H2,1-3H3	NEOVVLWTAJNEGT-UHFFFAOYSA-N	50387809	CHEMBL2058369	Endothelin-1 receptor			 22							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387809&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70692693	160866892		CHEMBL2058369				ZINC84703646	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945429	CCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H30N4O3S/c1-4-5-14-28-30-25-11-7-8-12-26(25)33(28)19-22-15-17-23(18-16-22)24-10-6-9-13-27(24)37(34,35)32-29-20(2)21(3)31-36-29/h6-13,15-18,32H,4-5,14,19H2,1-3H3	YABUJJGOFUBCLX-UHFFFAOYSA-N	50387810	CHEMBL2058370	Endothelin-1 receptor			 9.8							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387810&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70686382	160866893		CHEMBL2058370				ZINC84703649	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945430	CCCCc1nc2ccc(C)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H32N4O3S/c1-5-6-11-29-31-26-17-12-20(2)18-27(26)34(29)19-23-13-15-24(16-14-23)25-9-7-8-10-28(25)38(35,36)33-30-21(3)22(4)32-37-30/h7-10,12-18,33H,5-6,11,19H2,1-4H3	GYQLFYZRZOFFKO-UHFFFAOYSA-N	50387811	CHEMBL2058371	Endothelin-1 receptor			 9.3							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387811&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70684239	160866894		CHEMBL2058371				ZINC84690588	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945431	CCCCc1nc2ccc(OC)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C30H32N4O4S/c1-5-6-11-29-31-26-17-16-24(37-4)18-27(26)34(29)19-22-12-14-23(15-13-22)25-9-7-8-10-28(25)39(35,36)33-30-20(2)21(3)32-38-30/h7-10,12-18,33H,5-6,11,19H2,1-4H3	YKXROLRWINCJGF-UHFFFAOYSA-N	50387812	CHEMBL2058372	Endothelin-1 receptor			 8.9							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387812&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70694737	160866895		CHEMBL2058372				ZINC84703809	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945432	CCCCc1nc2ccc(Cl)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H29ClN4O3S/c1-4-5-10-28-31-25-16-15-23(30)17-26(25)34(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)38(35,36)33-29-19(2)20(3)32-37-29/h6-9,11-17,33H,4-5,10,18H2,1-3H3	QGSWJFKEWYYDIG-UHFFFAOYSA-N	50387805	CHEMBL2058373	Endothelin-1 receptor			 9.6							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387805&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70694738	160866888		CHEMBL2058373				ZINC84690772	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945433	CCCCc1nc2ccc(Br)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H29BrN4O3S/c1-4-5-10-28-31-25-16-15-23(30)17-26(25)34(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)38(35,36)33-29-19(2)20(3)32-37-29/h6-9,11-17,33H,4-5,10,18H2,1-3H3	PDVOEHGCFMJVQS-UHFFFAOYSA-N	50387813	CHEMBL2058374	Endothelin-1 receptor			 9.8							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387813&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70696780	160866896		CHEMBL2058374				ZINC84690206	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945434	CCCCc1nc2ccc(F)cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C29H29FN4O3S/c1-4-5-10-28-31-25-16-15-23(30)17-26(25)34(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)38(35,36)33-29-19(2)20(3)32-37-29/h6-9,11-17,33H,4-5,10,18H2,1-3H3	ZQVLYQIYBWIADD-UHFFFAOYSA-N	50387814	CHEMBL2058375	Endothelin-1 receptor			 10							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387814&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70690542	160866897		CHEMBL2058375				ZINC84690207	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945435	CCCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)C(F)(F)F	InChI=1S/C30H29F3N4O3S/c1-4-5-10-28-34-25-16-15-23(30(31,32)33)17-26(25)37(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)41(38,39)36-29-19(2)20(3)35-40-29/h6-9,11-17,36H,4-5,10,18H2,1-3H3	BZQHFABDJBRUMK-UHFFFAOYSA-N	50387815	CHEMBL2058376	Endothelin-1 receptor			 10							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387815&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70696781	160866898		CHEMBL2058376				ZINC84690208	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945436	CCCCc1nc2ccc(cc2n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C)[N+]([O-])=O	InChI=1S/C29H29N5O5S/c1-4-5-10-28-30-25-16-15-23(34(35)36)17-26(25)33(28)18-21-11-13-22(14-12-21)24-8-6-7-9-27(24)40(37,38)32-29-19(2)20(3)31-39-29/h6-9,11-17,32H,4-5,10,18H2,1-3H3	PSQMXFUCTHDZBE-UHFFFAOYSA-N	50387816	CHEMBL2058377	Endothelin-1 receptor			 11							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50387816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50387816&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70684240	160866899		CHEMBL2058377				ZINC84690503	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945437	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 8.9							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945438	CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C38H42N4O6S/c1-7-9-28-19-26(21-42-34(8-2)40-35-24(5)18-25(6)39-37(35)42)10-16-31(28)48-36(29-13-17-32-33(20-29)47-22-46-32)38(43)41-49(44,45)30-14-11-27(12-15-30)23(3)4/h10-20,23,36H,7-9,21-22H2,1-6H3,(H,41,43)	NTQWAQFOJQQOTK-UHFFFAOYSA-N	50117909	CHEMBL278176::N-{2-Benzo[1,3]dioxol-5-yl-2-[4-(2-ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-acetyl}-4-isopropyl-benzenesulfonamide	Endothelin-1 receptor			 24							ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117909&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9896251	104011317		CHEMBL278176				ZINC43317880	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50945440	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(CN2CCC(C)(C)C2=O)c1)-c1ccccc1S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C36H45N5O5S/c1-6-7-14-31-37-36(17-10-11-18-36)34(43)41(31)22-26-15-16-28(27(21-26)23-40-20-19-35(4,5)33(40)42)29-12-8-9-13-30(29)47(44,45)39-32-24(2)25(3)38-46-32/h8-9,12-13,15-16,21,39H,6-7,10-11,14,17-20,22-23H2,1-5H3	NBDFXMDYBLSGLX-UHFFFAOYSA-N	50117910	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2''-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2'-(3,3-dimethyl-2-oxo-pyrrolidin-1-ylmethyl)-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::BMS-248360::CHEMBL11706	Endothelin-1 receptor		 1.9								ChEMBL	10.1016/j.bmc.2012.06.011	10.7270/Q2G73FS6	22750010			Bai, R; Wei, Z; Liu, J; Xie, W; Yao, H; Wu, X; Jiang, J; Wang, Q; Xu, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117910&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9895957	104011318		CHEMBL11706				ZINC26026608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964824	CCCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H21Br2N5O4S/c1-2-3-10-32(28,29)27-18-17(14-4-6-15(21)7-5-14)19(26-13-25-18)30-8-9-31-20-23-11-16(22)12-24-20/h4-7,11-13H,2-3,8-10H2,1H3,(H,25,26,27)	OZBDTKLWBSATSN-UHFFFAOYSA-N	50395617	CHEMBL2163694	Endothelin-1 receptor			 1.1							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395617&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71449713	163344641		CHEMBL2163694				ZINC95553975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964825	CCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H19Br2N5O4S/c1-2-9-31(27,28)26-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)29-7-8-30-19-22-10-15(21)11-23-19/h3-6,10-12H,2,7-9H2,1H3,(H,24,25,26)	GKNRICGPGVNSOP-UHFFFAOYSA-N	50395618	CHEMBL2163693	Endothelin-1 receptor			 2.2							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395618&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9916121	163344642		CHEMBL2163693				ZINC95553720	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964826	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1Oc1cc(OC)ccc1Cl	InChI=1S/C20H22BrClN6O6S/c1-3-6-27-35(29,30)28-18-17(34-16-9-14(31-2)4-5-15(16)22)19(26-12-25-18)32-7-8-33-20-23-10-13(21)11-24-20/h4-5,9-12,27H,3,6-8H2,1-2H3,(H,25,26,28)	FYDHNMUVDRWWCO-UHFFFAOYSA-N	50395619	CHEMBL2163692	Endothelin-1 receptor			 0.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395619&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462245	163344643		CHEMBL2163692				ZINC95553680	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964827	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1Oc1cccc(OC)c1	InChI=1S/C20H23BrN6O6S/c1-3-7-26-34(28,29)27-18-17(33-16-6-4-5-15(10-16)30-2)19(25-13-24-18)31-8-9-32-20-22-11-14(21)12-23-20/h4-6,10-13,26H,3,7-9H2,1-2H3,(H,24,25,27)	XYZWCNYWABHTRK-UHFFFAOYSA-N	50395620	CHEMBL2163691	Endothelin-1 receptor			 1.9							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395620&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71453356	163344644		CHEMBL2163691				ZINC95552472	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964828	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C19H20BrClN6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-15(21)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-14(20)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)	OXHAHXSAOMBNOX-UHFFFAOYSA-N	50395621	CHEMBL2163690	Endothelin-1 receptor			 1.2							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395621&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041324	163344645		CHEMBL2163690				ZINC95556431	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964829	Brc1ccc(cc1)-c1c(NS(=O)(=O)N2CCOCC2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C20H20Br2N6O5S/c21-15-3-1-14(2-4-15)17-18(27-34(29,30)28-5-7-31-8-6-28)25-13-26-19(17)32-9-10-33-20-23-11-16(22)12-24-20/h1-4,11-13H,5-10H2,(H,25,26,27)	XCUHHFLCIVGCRF-UHFFFAOYSA-N	50395622	CHEMBL2163689	Endothelin-1 receptor			 2.8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395622&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455060	163344646		CHEMBL2163689				ZINC95554438	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964830	CN(Cc1ccccc1)S(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C24H22Br2N6O4S/c1-32(15-17-5-3-2-4-6-17)37(33,34)31-22-21(18-7-9-19(25)10-8-18)23(30-16-29-22)35-11-12-36-24-27-13-20(26)14-28-24/h2-10,13-14,16H,11-12,15H2,1H3,(H,29,30,31)	KUJMAODMTWXUGC-UHFFFAOYSA-N	50395623	CHEMBL2163688	Endothelin-1 receptor			 4.3							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395623&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041249	163344647		CHEMBL2163688				ZINC95553732	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964831	Brc1ccc(cc1)-c1c(NS(=O)(=O)NC2CC2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C19H18Br2N6O4S/c20-13-3-1-12(2-4-13)16-17(27-32(28,29)26-15-5-6-15)24-11-25-18(16)30-7-8-31-19-22-9-14(21)10-23-19/h1-4,9-11,15,26H,5-8H2,(H,24,25,27)	LKOLDYBWXOYQMQ-UHFFFAOYSA-N	50395624	CHEMBL2165340	Endothelin-1 receptor			 4.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395624&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041266	163344648		CHEMBL2165340				ZINC95555387	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964832	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H22Br2N6O4S/c1-2-3-8-27-33(29,30)28-18-17(14-4-6-15(21)7-5-14)19(26-13-25-18)31-9-10-32-20-23-11-16(22)12-24-20/h4-7,11-13,27H,2-3,8-10H2,1H3,(H,25,26,28)	FAYAMAAFPRXGJT-UHFFFAOYSA-N	50395625	CHEMBL2165339	Endothelin-1 receptor			 0.3							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395625&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041264	163344649		CHEMBL2165339				ZINC95554334	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964833	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)	JGCMEBMXRHSZKX-UHFFFAOYSA-N	50395626	ACT-064992::MACITENTAN	Endothelin-1 receptor			 0.5							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395626&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16004692	163344650			DB08932			ZINC43202140	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964834	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C18H18Br2N6O4S/c1-2-25-31(27,28)26-16-15(12-3-5-13(19)6-4-12)17(24-11-23-16)29-7-8-30-18-21-9-14(20)10-22-18/h3-6,9-11,25H,2,7-8H2,1H3,(H,23,24,26)	PIJUSICWAKBTEZ-UHFFFAOYSA-N	50395627	CHEMBL2165338	Endothelin-1 receptor			 0.8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395627&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462322	163344651		CHEMBL2165338				ZINC95552839	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964835	CNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C17H16Br2N6O4S/c1-20-30(26,27)25-15-14(11-2-4-12(18)5-3-11)16(24-10-23-15)28-6-7-29-17-21-8-13(19)9-22-17/h2-5,8-10,20H,6-7H2,1H3,(H,23,24,25)	BRSITRUZDCGGKH-UHFFFAOYSA-N	50395628	CHEMBL2165337	Endothelin-1 receptor			 1.7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395628&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041267	163344652		CHEMBL2165337				ZINC95555362	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964836	CC(C)c1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C26H27BrN6O4S/c1-18(2)20-8-10-21(11-9-20)23-24(33-38(34,35)32-14-19-6-4-3-5-7-19)30-17-31-25(23)36-12-13-37-26-28-15-22(27)16-29-26/h3-11,15-18,32H,12-14H2,1-2H3,(H,30,31,33)	YBMIXYLICGEZNV-UHFFFAOYSA-N	50395629	CHEMBL2165336	Endothelin-1 receptor			 3.6							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395629&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455140	163344653		CHEMBL2165336				ZINC95554045	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964837	CCc1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C25H25BrN6O4S/c1-2-18-8-10-20(11-9-18)22-23(32-37(33,34)31-14-19-6-4-3-5-7-19)29-17-30-24(22)35-12-13-36-25-27-15-21(26)16-28-25/h3-11,15-17,31H,2,12-14H2,1H3,(H,29,30,32)	DTSHFCFWFUAWDU-UHFFFAOYSA-N	50395630	CHEMBL2165335	Endothelin-1 receptor			 2.3							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395630&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462321	163344654		CHEMBL2165335				ZINC95553198	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964838	Brc1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C23H20Br2N6O4S/c24-18-8-6-17(7-9-18)20-21(31-36(32,33)30-12-16-4-2-1-3-5-16)28-15-29-22(20)34-10-11-35-23-26-13-19(25)14-27-23/h1-9,13-15,30H,10-12H2,(H,28,29,31)	VIQIKJNRAFJKTQ-UHFFFAOYSA-N	50395631	CHEMBL2165334	Endothelin-1 receptor			 1.6							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395631&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			67952994	163344655		CHEMBL2165334				ZINC95552225	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964839	Clc1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C23H20BrClN6O4S/c24-18-13-26-23(27-14-18)35-11-10-34-22-20(17-6-8-19(25)9-7-17)21(28-15-29-22)31-36(32,33)30-12-16-4-2-1-3-5-16/h1-9,13-15,30H,10-12H2,(H,28,29,31)	RULBFQDDCRBSBY-UHFFFAOYSA-N	50395632	CHEMBL2165333	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395632&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21979593	163344656		CHEMBL2165333				ZINC01552959	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964840	Cc1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C24H23BrN6O4S/c1-17-7-9-19(10-8-17)21-22(31-36(32,33)30-13-18-5-3-2-4-6-18)28-16-29-23(21)34-11-12-35-24-26-14-20(25)15-27-24/h2-10,14-16,30H,11-13H2,1H3,(H,28,29,31)	BIHSQJMJRJBBHK-UHFFFAOYSA-N	50395633	CHEMBL2165332	Endothelin-1 receptor			 0.7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395633&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462320	163344657		CHEMBL2165332				ZINC95556464	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964841	Brc1cnc(OCCOc2ncnc(NS(=O)(=O)NCc3ccccc3)c2-c2ccccc2)nc1	InChI=1S/C23H21BrN6O4S/c24-19-14-25-23(26-15-19)34-12-11-33-22-20(18-9-5-2-6-10-18)21(27-16-28-22)30-35(31,32)29-13-17-7-3-1-4-8-17/h1-10,14-16,29H,11-13H2,(H,27,28,30)	NECQSUNUSOOPMU-UHFFFAOYSA-N	50395634	CHEMBL2165331	Endothelin-1 receptor			 6.8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395634&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455139	163344658		CHEMBL2165331				ZINC95552809	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964842	COc1ccc(Cl)c(Oc2c(NS(=O)(=O)NCc3ccccc3)ncnc2OCCOc2ncc(Br)cn2)c1	InChI=1S/C24H22BrClN6O6S/c1-35-18-7-8-19(26)20(11-18)38-21-22(32-39(33,34)31-12-16-5-3-2-4-6-16)29-15-30-23(21)36-9-10-37-24-27-13-17(25)14-28-24/h2-8,11,13-15,31H,9-10,12H2,1H3,(H,29,30,32)	ADKWUFCPMCLUKI-UHFFFAOYSA-N	50395635	CHEMBL2165330	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395635&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041370	163344659		CHEMBL2165330				ZINC95556399	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964843	COc1cccc(Oc2c(NS(=O)(=O)NCc3ccccc3)ncnc2OCCOc2ncc(Br)cn2)c1	InChI=1S/C24H23BrN6O6S/c1-34-19-8-5-9-20(12-19)37-21-22(31-38(32,33)30-13-17-6-3-2-4-7-17)28-16-29-23(21)35-10-11-36-24-26-14-18(25)15-27-24/h2-9,12,14-16,30H,10-11,13H2,1H3,(H,28,29,31)	WBTXDANWVHPDGU-UHFFFAOYSA-N	50395636	CHEMBL2165329	Endothelin-1 receptor			 1							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395636&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71460621	163344660		CHEMBL2165329				ZINC95553216	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964844	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C24H23BrN6O6S/c1-34-19-9-5-6-10-20(19)37-21-22(31-38(32,33)30-13-17-7-3-2-4-8-17)28-16-29-23(21)35-11-12-36-24-26-14-18(25)15-27-24/h2-10,14-16,30H,11-13H2,1H3,(H,28,29,31)	LSQXFROVPNDBMN-UHFFFAOYSA-N	50395637	CHEMBL2165328	Endothelin-1 receptor			 6.9							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395637&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21979601	163344661		CHEMBL2165328				ZINC95557550	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964845	COCCOc1nc(NS(=O)(=O)NCc2ccccc2)c(Oc2ccccc2OC)c(OCCOc2ncc(Br)cn2)n1	InChI=1S/C27H29BrN6O8S/c1-37-12-13-41-27-32-24(34-43(35,36)31-16-19-8-4-3-5-9-19)23(42-22-11-7-6-10-21(22)38-2)25(33-27)39-14-15-40-26-29-17-20(28)18-30-26/h3-11,17-18,31H,12-16H2,1-2H3,(H,32,33,34)	VIVHYWNEMYNSTR-UHFFFAOYSA-N	50395638	CHEMBL2163728	Endothelin-1 receptor			 6.9							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395638&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462248	163344662		CHEMBL2163728				ZINC95556471	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964846	COc1nc(NS(=O)(=O)NCc2ccccc2)c(Oc2ccccc2OC)c(OCCOc2ncc(Br)cn2)n1	InChI=1S/C25H25BrN6O7S/c1-35-19-10-6-7-11-20(19)39-21-22(32-40(33,34)29-14-17-8-4-3-5-9-17)30-25(36-2)31-23(21)37-12-13-38-24-27-15-18(26)16-28-24/h3-11,15-16,29H,12-14H2,1-2H3,(H,30,31,32)	UDSNDBJKDSPRDS-UHFFFAOYSA-N	50395639	CHEMBL2163727	Endothelin-1 receptor			 40							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395639&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456865	163344663		CHEMBL2163727				ZINC95553932	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964847	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)C1CC1	InChI=1S/C27H27BrN6O6S/c1-37-21-9-5-6-10-22(21)40-23-25(34-41(35,36)31-15-18-7-3-2-4-8-18)32-24(19-11-12-19)33-26(23)38-13-14-39-27-29-16-20(28)17-30-27/h2-10,16-17,19,31H,11-15H2,1H3,(H,32,33,34)	FFMVLDUPAMRSND-UHFFFAOYSA-N	50395640	CHEMBL2163726	Endothelin-1 receptor			 14							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395640&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458721	163344664		CHEMBL2163726				ZINC95552854	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964848	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)N1CCOCC1	InChI=1S/C28H30BrN7O7S/c1-39-22-9-5-6-10-23(22)43-24-25(35-44(37,38)32-17-20-7-3-2-4-8-20)33-27(36-11-13-40-14-12-36)34-26(24)41-15-16-42-28-30-18-21(29)19-31-28/h2-10,18-19,32H,11-17H2,1H3,(H,33,34,35)	SENIALTXHXJCNY-UHFFFAOYSA-N	50395641	CHEMBL2163725	Endothelin-1 receptor			 1.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395641&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041372	163344665		CHEMBL2163725				ZINC95553908	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964849	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ccncc1	InChI=1S/C29H26BrN7O6S/c1-40-23-9-5-6-10-24(23)43-25-27(37-44(38,39)34-17-20-7-3-2-4-8-20)35-26(21-11-13-31-14-12-21)36-28(25)41-15-16-42-29-32-18-22(30)19-33-29/h2-14,18-19,34H,15-17H2,1H3,(H,35,36,37)	KSWCYNIYGNMXLW-UHFFFAOYSA-N	50395642	CHEMBL2163724	Endothelin-1 receptor			 3.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395642&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455065	163344666		CHEMBL2163724				ZINC95553665	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964850	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1cnccn1	InChI=1S/C28H25BrN8O6S/c1-40-22-9-5-6-10-23(22)43-24-26(37-44(38,39)34-15-19-7-3-2-4-8-19)35-25(21-18-30-11-12-31-21)36-27(24)41-13-14-42-28-32-16-20(29)17-33-28/h2-12,16-18,34H,13-15H2,1H3,(H,35,36,37)	QYVHDIUYFHTCJX-UHFFFAOYSA-N	50395643	CHEMBL2163723	Endothelin-1 receptor			 2.1							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395643&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462247	163344667		CHEMBL2163723				ZINC95553918	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964851	COc1ccccc1Oc1c(NS(=O)(=O)N2CCOCC2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C25H25BrN8O7S/c1-37-18-5-2-3-6-19(18)41-20-21(33-42(35,36)34-9-11-38-12-10-34)31-23(22-27-7-4-8-28-22)32-24(20)39-13-14-40-25-29-15-17(26)16-30-25/h2-8,15-16H,9-14H2,1H3,(H,31,32,33)	BCPQODVHPDJJAT-UHFFFAOYSA-N	50395644	CHEMBL2163722	Endothelin-1 receptor			 187							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395644&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71460537	163344668		CHEMBL2163722				ZINC95553733	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964852	COc1ccccc1Oc1c(NS(=O)(=O)N(C)Cc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C29H27BrN8O6S/c1-38(19-20-9-4-3-5-10-20)45(39,40)37-25-24(44-23-12-7-6-11-22(23)41-2)28(36-27(35-25)26-31-13-8-14-32-26)42-15-16-43-29-33-17-21(30)18-34-29/h3-14,17-18H,15-16,19H2,1-2H3,(H,35,36,37)	UGJAKYVVBJWFEZ-UHFFFAOYSA-N	50395645	CHEMBL2163721	Endothelin-1 receptor			 7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395645&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455064	163344669		CHEMBL2163721				ZINC95556122	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964853	CCCCNS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C25H27BrN8O6S/c1-3-4-12-31-41(35,36)34-21-20(40-19-9-6-5-8-18(19)37-2)24(33-23(32-21)22-27-10-7-11-28-22)38-13-14-39-25-29-15-17(26)16-30-25/h5-11,15-16,31H,3-4,12-14H2,1-2H3,(H,32,33,34)	ARFNEXZBRRNUKE-UHFFFAOYSA-N	50395646	CHEMBL2163720	Endothelin-1 receptor			 1.7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395646&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455063	163344670		CHEMBL2163720				ZINC95556084	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964854	CCCNS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C24H25BrN8O6S/c1-3-9-30-40(34,35)33-20-19(39-18-8-5-4-7-17(18)36-2)23(32-22(31-20)21-26-10-6-11-27-21)37-12-13-38-24-28-14-16(25)15-29-24/h4-8,10-11,14-15,30H,3,9,12-13H2,1-2H3,(H,31,32,33)	VUAQGALNRBYHNG-UHFFFAOYSA-N	50395647	CHEMBL2163719	Endothelin-1 receptor			 3.8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395647&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451529	163344671		CHEMBL2163719				ZINC95557185	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964855	CCNS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C23H23BrN8O6S/c1-3-29-39(33,34)32-19-18(38-17-8-5-4-7-16(17)35-2)22(31-21(30-19)20-25-9-6-10-26-20)36-11-12-37-23-27-13-15(24)14-28-23/h4-10,13-14,29H,3,11-12H2,1-2H3,(H,30,31,32)	MIPNODJPKTVQHX-UHFFFAOYSA-N	50395648	CHEMBL2163718	Endothelin-1 receptor			 9.9							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395648&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456864	163344672		CHEMBL2163718				ZINC95552815	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964856	CNS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C22H21BrN8O6S/c1-24-38(32,33)31-18-17(37-16-7-4-3-6-15(16)34-2)21(30-20(29-18)19-25-8-5-9-26-19)35-10-11-36-22-27-12-14(23)13-28-22/h3-9,12-13,24H,10-11H2,1-2H3,(H,29,30,31)	MOXPGMJEOXCNPF-UHFFFAOYSA-N	50395649	CHEMBL2163717	Endothelin-1 receptor			 7.9							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395649&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462246	163344673		CHEMBL2163717				ZINC95552206	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964857	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C28H25BrN8O6S/c1-40-21-10-5-6-11-22(21)43-23-24(37-44(38,39)34-16-19-8-3-2-4-9-19)35-26(25-30-12-7-13-31-25)36-27(23)41-14-15-42-28-32-17-20(29)18-33-28/h2-13,17-18,34H,14-16H2,1H3,(H,35,36,37)	MNRPBSOBVCAVNX-UHFFFAOYSA-N	50395650	CHEMBL2163716	Endothelin-1 receptor			 1.9							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395650&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456863	163344674		CHEMBL2163716				ZINC95552081	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964858	CCCCS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C25H26BrN7O6S/c1-3-4-14-40(34,35)33-21-20(39-19-9-6-5-8-18(19)36-2)24(32-23(31-21)22-27-10-7-11-28-22)37-12-13-38-25-29-15-17(26)16-30-25/h5-11,15-16H,3-4,12-14H2,1-2H3,(H,31,32,33)	YPXSZXRASAVIKK-UHFFFAOYSA-N	50395651	CHEMBL2163715	Endothelin-1 receptor			 4.3							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395651&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451528	163344675		CHEMBL2163715				ZINC95552921	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964859	CCCS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C24H24BrN7O6S/c1-3-13-39(33,34)32-20-19(38-18-8-5-4-7-17(18)35-2)23(31-22(30-20)21-26-9-6-10-27-21)36-11-12-37-24-28-14-16(25)15-29-24/h4-10,14-15H,3,11-13H2,1-2H3,(H,30,31,32)	QLOACGMSZNOMDZ-UHFFFAOYSA-N	50395652	CHEMBL2163714	Endothelin-1 receptor			 9.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395652&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10129267	163344676		CHEMBL2163714				ZINC95556792	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964860	CCS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C23H22BrN7O6S/c1-3-38(32,33)31-19-18(37-17-8-5-4-7-16(17)34-2)22(30-21(29-19)20-25-9-6-10-26-20)35-11-12-36-23-27-13-15(24)14-28-23/h4-10,13-14H,3,11-12H2,1-2H3,(H,29,30,31)	CMPCSJBKUBWQGQ-UHFFFAOYSA-N	50395653	CHEMBL2163713	Endothelin-1 receptor			 14							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395653&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10240093	163344677		CHEMBL2163713				ZINC95552457	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964861	COc1ccccc1Oc1c(NS(C)(=O)=O)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C22H20BrN7O6S/c1-33-15-6-3-4-7-16(15)36-17-18(30-37(2,31)32)28-20(19-24-8-5-9-25-19)29-21(17)34-10-11-35-22-26-12-14(23)13-27-22/h3-9,12-13H,10-11H2,1-2H3,(H,28,29,30)	OOHIDBZEWZXHNX-UHFFFAOYSA-N	50395654	CHEMBL2163712	Endothelin-1 receptor			 113							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395654&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71460536	163344678		CHEMBL2163712				ZINC95552144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964862	COc1ccccc1Oc1c(NS(=O)(=O)CCCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C30H28BrN7O6S/c1-41-23-12-5-6-13-24(23)44-25-26(38-45(39,40)18-7-11-21-9-3-2-4-10-21)36-28(27-32-14-8-15-33-27)37-29(25)42-16-17-43-30-34-19-22(31)20-35-30/h2-6,8-10,12-15,19-20H,7,11,16-18H2,1H3,(H,36,37,38)	MHNJEAOUFUNYKE-UHFFFAOYSA-N	50395655	CHEMBL2163711	Endothelin-1 receptor			 6.7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395655&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71460535	163344679		CHEMBL2163711				ZINC95553286	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964863	COc1ccccc1Oc1c(NS(=O)(=O)Cc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C28H24BrN7O6S/c1-39-21-10-5-6-11-22(21)42-23-24(36-43(37,38)18-19-8-3-2-4-9-19)34-26(25-30-12-7-13-31-25)35-27(23)40-14-15-41-28-32-16-20(29)17-33-28/h2-13,16-17H,14-15,18H2,1H3,(H,34,35,36)	CUPYKYWQFHCUJZ-UHFFFAOYSA-N	50395656	CHEMBL2163710	Endothelin-1 receptor			 73							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395656&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458720	163344680		CHEMBL2163710				ZINC95554696	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964864	COc1ccccc1Oc1c(NS(=O)(=O)c2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C27H22BrN7O6S/c1-38-20-10-5-6-11-21(20)41-22-23(35-42(36,37)19-8-3-2-4-9-19)33-25(24-29-12-7-13-30-24)34-26(22)39-14-15-40-27-31-16-18(28)17-32-27/h2-13,16-17H,14-15H2,1H3,(H,33,34,35)	VAXUKYCSAUELNZ-UHFFFAOYSA-N	50395657	CHEMBL2163709	Endothelin-1 receptor			 10.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395657&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456862	163344681		CHEMBL2163709				ZINC95553197	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964865	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C31H30BrN7O6S/c1-31(2,3)20-10-12-22(13-11-20)46(40,41)39-26-25(45-24-9-6-5-8-23(24)42-4)29(38-28(37-26)27-33-14-7-15-34-27)43-16-17-44-30-35-18-21(32)19-36-30/h5-15,18-19H,16-17H2,1-4H3,(H,37,38,39)	UTSKZBKTKROJBZ-UHFFFAOYSA-N	50395658	CHEMBL2163708	Endothelin-1 receptor			 1.5							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395658&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71453357	163344682		CHEMBL2163708				ZINC95552080	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964866	COc1cc(OC)nc(OCCOc2nc(nc(NS(=O)(=O)CCc3ccccc3)c2Oc2ccccc2OC)-c2ncccn2)n1	InChI=1S/C31H31N7O8S/c1-41-22-12-7-8-13-23(22)46-26-27(38-47(39,40)19-14-21-10-5-4-6-11-21)36-29(28-32-15-9-16-33-28)37-30(26)44-17-18-45-31-34-24(42-2)20-25(35-31)43-3/h4-13,15-16,20H,14,17-19H2,1-3H3,(H,36,37,38)	RUZZWMQTBLUKQJ-UHFFFAOYSA-N	50395659	CHEMBL2163707	Endothelin-1 receptor			 4775							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395659&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23548251	163344683		CHEMBL2163707				ZINC95552846	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964867	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(cn1)C1CC1)-c1ncccn1	InChI=1S/C32H31N7O6S/c1-42-25-10-5-6-11-26(25)45-27-28(39-46(40,41)19-14-22-8-3-2-4-9-22)37-30(29-33-15-7-16-34-29)38-31(27)43-17-18-44-32-35-20-24(21-36-32)23-12-13-23/h2-11,15-16,20-21,23H,12-14,17-19H2,1H3,(H,37,38,39)	CFOMGVYXSNFELK-UHFFFAOYSA-N	50395660	CHEMBL2163706	Endothelin-1 receptor			 7.7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395660&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451527	163344684		CHEMBL2163706				ZINC95557554	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964868	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(cn1)C(F)(F)F)-c1ncccn1	InChI=1S/C30H26F3N7O6S/c1-43-22-10-5-6-11-23(22)46-24-25(40-47(41,42)17-12-20-8-3-2-4-9-20)38-27(26-34-13-7-14-35-26)39-28(24)44-15-16-45-29-36-18-21(19-37-29)30(31,32)33/h2-11,13-14,18-19H,12,15-17H2,1H3,(H,38,39,40)	BTPMMVWQHRCMQR-UHFFFAOYSA-N	50395661	CHEMBL2163705	Endothelin-1 receptor			 3							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395661&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455062	163344685		CHEMBL2163705				ZINC95554322	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964869	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(SC)cn1)-c1ncccn1	InChI=1S/C30H29N7O6S2/c1-40-23-11-6-7-12-24(23)43-25-26(37-45(38,39)18-13-21-9-4-3-5-10-21)35-28(27-31-14-8-15-32-27)36-29(25)41-16-17-42-30-33-19-22(44-2)20-34-30/h3-12,14-15,19-20H,13,16-18H2,1-2H3,(H,35,36,37)	JOBIZVVLDQEHKD-UHFFFAOYSA-N	50395662	CHEMBL2163704	Endothelin-1 receptor			 1.1							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395662&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458719	163344686		CHEMBL2163704				ZINC95552604	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964870	COc1cnc(OCCOc2nc(nc(NS(=O)(=O)CCc3ccccc3)c2Oc2ccccc2OC)-c2ncccn2)nc1	InChI=1S/C30H29N7O7S/c1-40-22-19-33-30(34-20-22)43-17-16-42-29-25(44-24-12-7-6-11-23(24)41-2)26(35-28(36-29)27-31-14-8-15-32-27)37-45(38,39)18-13-21-9-4-3-5-10-21/h3-12,14-15,19-20H,13,16-18H2,1-2H3,(H,35,36,37)	DAZOXLCENQFWSQ-UHFFFAOYSA-N	50395663	CHEMBL2163703	Endothelin-1 receptor			 3.2							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395663&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10122033	163344687		CHEMBL2163703				ZINC95554687	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964871	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C29H26BrN7O6S/c1-40-22-10-5-6-11-23(22)43-24-25(37-44(38,39)17-12-20-8-3-2-4-9-20)35-27(26-31-13-7-14-32-26)36-28(24)41-15-16-42-29-33-18-21(30)19-34-29/h2-11,13-14,18-19H,12,15-17H2,1H3,(H,35,36,37)	DEOGRJUDPLWPSR-UHFFFAOYSA-N	50395664	CHEMBL2163702	Endothelin-1 receptor			 2.2							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395664&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23548253	163344688		CHEMBL2163702				ZINC95555792	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964872	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(Cl)cn1)-c1ncccn1	InChI=1S/C29H26ClN7O6S/c1-40-22-10-5-6-11-23(22)43-24-25(37-44(38,39)17-12-20-8-3-2-4-9-20)35-27(26-31-13-7-14-32-26)36-28(24)41-15-16-42-29-33-18-21(30)19-34-29/h2-11,13-14,18-19H,12,15-17H2,1H3,(H,35,36,37)	RJXHHVXIVAHBHS-UHFFFAOYSA-N	50395665	CHEMBL2163701	Endothelin-1 receptor			 2.8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395665&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451526	163344689		CHEMBL2163701				ZINC95554993	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964873	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(C)cn1)-c1ncccn1	InChI=1S/C30H29N7O6S/c1-21-19-33-30(34-20-21)42-17-16-41-29-25(43-24-12-7-6-11-23(24)40-2)26(35-28(36-29)27-31-14-8-15-32-27)37-44(38,39)18-13-22-9-4-3-5-10-22/h3-12,14-15,19-20H,13,16-18H2,1-2H3,(H,35,36,37)	IBQQNRNUTUTRGT-UHFFFAOYSA-N	50395666	CHEMBL2163700	Endothelin-1 receptor			 17.8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395666&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458718	163344690		CHEMBL2163700				ZINC95554067	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964874	COc1ccccc1Oc1c(NS(C)(=O)=O)nc(nc1OCCOc1ncccn1)-c1ncccn1	InChI=1S/C22H21N7O6S/c1-32-15-7-3-4-8-16(15)35-17-18(29-36(2,30)31)27-20(19-23-9-5-10-24-19)28-21(17)33-13-14-34-22-25-11-6-12-26-22/h3-12H,13-14H2,1-2H3,(H,27,28,29)	SNBHOBPELVBJFV-UHFFFAOYSA-N	50395667	CHEMBL2163699	Endothelin-1 receptor			 739							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395667&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71455061	163344691		CHEMBL2163699				ZINC95557490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964875	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncccn1)-c1ncccn1	InChI=1S/C29H27N7O6S/c1-39-22-11-5-6-12-23(22)42-24-25(36-43(37,38)20-13-21-9-3-2-4-10-21)34-27(26-30-14-7-15-31-26)35-28(24)40-18-19-41-29-32-16-8-17-33-29/h2-12,14-17H,13,18-20H2,1H3,(H,34,35,36)	WSNWXTKIOPWVDW-UHFFFAOYSA-N	50395668	CHEMBL2163698	Endothelin-1 receptor			 8							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395668&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10145418	163344692		CHEMBL2163698				ZINC95554443	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964876	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOc1ncccn1)-c1ncccn1	InChI=1S/C31H31N7O6S/c1-31(2,3)21-11-13-22(14-12-21)45(39,40)38-26-25(44-24-10-6-5-9-23(24)41-4)29(37-28(36-26)27-32-15-7-16-33-27)42-19-20-43-30-34-17-8-18-35-30/h5-18H,19-20H2,1-4H3,(H,36,37,38)	CBJKZXKXUSTFHL-UHFFFAOYSA-N	50395669	CHEMBL2163697	Endothelin-1 receptor			 4.3							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395669&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451525	163344693		CHEMBL2163697				ZINC95553714	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964877	COc1ccccc1Oc1c(NS(C)(=O)=O)nc(nc1OCCO)-c1ncccn1	InChI=1S/C18H19N5O6S/c1-27-12-6-3-4-7-13(12)29-14-15(23-30(2,25)26)21-17(16-19-8-5-9-20-16)22-18(14)28-11-10-24/h3-9,24H,10-11H2,1-2H3,(H,21,22,23)	KKURJWQDVAUNQC-UHFFFAOYSA-N	50395670	CHEMBL2163696	Endothelin-1 receptor			 4534							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395670&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71458717	163344694		CHEMBL2163696				ZINC95553645	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964878	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCO)-c1ncccn1	InChI=1S/C25H25N5O6S/c1-34-19-10-5-6-11-20(19)36-21-22(30-37(32,33)17-12-18-8-3-2-4-9-18)28-24(23-26-13-7-14-27-23)29-25(21)35-16-15-31/h2-11,13-14,31H,12,15-17H2,1H3,(H,28,29,30)	NGLUZGYJAMFNPH-UHFFFAOYSA-N	50395671	CHEMBL2163695	Endothelin-1 receptor			 25.7							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395671&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10218058	163344695		CHEMBL2163695				ZINC38391116	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964879	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 45							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964884	NS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C16H14Br2N6O4S/c17-11-3-1-10(2-4-11)13-14(24-29(19,25)26)22-9-23-15(13)27-5-6-28-16-20-7-12(18)8-21-16/h1-4,7-9H,5-6H2,(H2,19,25,26)(H,22,23,24)	DKULOVKANLVDEA-UHFFFAOYSA-N	50395672	CHEMBL2165326	Endothelin-1 receptor			 3.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395672&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			25099191	163344696		CHEMBL2165326				ZINC95553608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964886	Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)CO)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C27H28BrN5O5S/c1-18-4-6-19(7-5-18)23-24(33-39(35,36)22-10-8-20(9-11-22)27(2,3)16-34)31-17-32-25(23)37-12-13-38-26-29-14-21(28)15-30-26/h4-11,14-15,17,34H,12-13,16H2,1-3H3,(H,31,32,33)	YAWNVAQKVARTGQ-UHFFFAOYSA-N	50105051	CHEMBL112624::N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-4-(2-hydroxy-1,1-dimethyl-ethyl)-benzenesulfonamide	Endothelin-1 receptor			 0.4							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105051&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9852318	104000848		CHEMBL112624				ZINC08576535	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50964888	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(N)=O)NC2=O)[C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C103H147N27O37S5/c1-10-46(6)80(100(163)123-67(103(166)167)30-50-37-109-54-19-15-14-18-52(50)54)128-99(162)79(45(4)5)127-95(158)66(36-78(144)145)120-85(148)55(20-23-71(105)133)112-90(153)61(31-51-38-108-43-110-51)117-97(160)69-40-170-169-39-53(104)83(146)129-81(47(7)131)102(165)126-70-42-172-171-41-68(96(159)115-59(28-44(2)3)88(151)118-62(32-72(106)134)91(154)116-60(89(152)125-69)29-49-16-12-11-13-17-49)124-86(149)57(22-25-75(138)139)111-84(147)56(21-24-74(136)137)113-94(157)65(35-77(142)143)122-101(164)82(48(8)132)130-87(150)58(26-27-168-9)114-93(156)64(34-76(140)141)121-92(155)63(33-73(107)135)119-98(70)161/h11-19,37-38,43-48,53,55-70,79-82,109,131-132H,10,20-36,39-42,104H2,1-9H3,(H2,105,133)(H2,106,134)(H2,107,135)(H,108,110)(H,111,147)(H,112,153)(H,113,157)(H,114,156)(H,115,159)(H,116,154)(H,117,160)(H,118,151)(H,119,161)(H,120,148)(H,121,155)(H,122,164)(H,123,163)(H,124,149)(H,125,152)(H,126,165)(H,127,158)(H,128,162)(H,129,146)(H,130,150)(H,136,137)(H,138,139)(H,140,141)(H,142,143)(H,144,145)(H,166,167)/t46-,47+,48+,53-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,79-,80-,81-,82-/m0/s1	LXPHPKVWHQLBBA-JHOSIGDNSA-N	50395673	CHEMBL2165327	Endothelin-1 receptor			>100							ChEMBL	10.1021/jm3009103	10.7270/Q21C1XZT	22862294			Bolli, MH; Boss, C; Binkert, C; Buchmann, S; Bur, D; Hess, P; Iglarz, M; Meyer, S; Rein, J; Rey, M; Treiber, A; Clozel, M; Fischli, W; Weller, T	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395673&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456935	163344697		CHEMBL2165327					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50971361	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(c(COCC)c1)-c1ccccc1S(=O)(=O)Nc1noc(C)c1C	InChI=1S/C32H40N4O5S/c1-5-7-14-29-33-32(17-10-11-18-32)31(37)36(29)20-24-15-16-26(25(19-24)21-40-6-2)27-12-8-9-13-28(27)42(38,39)35-30-22(3)23(4)41-34-30/h8-9,12-13,15-16,19H,5-7,10-11,14,17-18,20-21H2,1-4H3,(H,34,35)	WRFHGDPIDHPWIQ-UHFFFAOYSA-N	50175523	4''-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2''-ethoxymethyl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide::4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-ylmethyl)-2'-ethoxymethyl-biphenyl-2-sulfonic acid (4,5-dimethyl-isoxazol-3-yl)-amide::CHEMBL539423	Endothelin-1 receptor		 9.3								ChEMBL	10.1021/jm300682j	10.7270/Q2862HKR	22931505			Pease, J; Horuk, R	National Heart and Lung Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175523&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10257882	104061216		CHEMBL539423				ZINC28116760	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50971363	Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C	InChI=1S/C20H17N3O4S/c1-13-14(2)22-27-19(13)23-28(24,25)18-6-4-3-5-17(18)15-7-9-16(10-8-15)20-21-11-12-26-20/h3-12,23H,1-2H3	LJGUZUROJOJEMI-UHFFFAOYSA-N	50091105	4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide::BMS-193884::CHEMBL24461	Endothelin-1 receptor		 1.4								ChEMBL	10.1021/jm300682j	10.7270/Q2862HKR	22931505			Pease, J; Horuk, R	National Heart and Lung Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091105&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9843631	103989493		CHEMBL24461				ZINC00836695	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50971365	CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1	InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)	YOSHYTLCDANDAN-UHFFFAOYSA-N	50042235	2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one::BMS 186295::CHEMBL1513::IRBESARTAN	Endothelin-1 receptor		 10000								ChEMBL	10.1021/jm300682j	10.7270/Q2862HKR	22931505			Pease, J; Horuk, R	National Heart and Lung Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3749	103973843		CHEMBL1513		589	C07469	ZINC13298436	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50523917	CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O	InChI=1S/C109H160N26O31S5/c1-12-56(9)87(108(165)119-69(89(112)146)39-60-43-114-65-24-18-17-23-63(60)65)135-109(166)88(57(10)13-2)134-100(157)76(42-85(144)145)125-95(152)71(36-54(5)6)120-98(155)74(40-61-44-113-52-115-61)123-104(161)80-49-169-168-48-64(111)90(147)127-77(45-136)103(160)132-81-50-170-171-51-82(106(163)133-86(55(7)8)107(164)126-73(38-59-26-28-62(139)29-27-59)96(153)122-72(97(154)131-80)37-58-21-15-14-16-22-58)130-92(149)67(30-31-83(140)141)117-91(148)66(25-19-20-33-110)116-99(156)75(41-84(142)143)124-93(150)68(32-34-167-11)118-94(151)70(35-53(3)4)121-101(158)78(46-137)128-102(159)79(47-138)129-105(81)162/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,114,136-139H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H2,112,146)(H,113,115)(H,116,156)(H,117,148)(H,118,151)(H,119,165)(H,120,155)(H,121,158)(H,122,153)(H,123,161)(H,124,150)(H,125,152)(H,126,164)(H,127,147)(H,128,159)(H,129,162)(H,130,149)(H,131,154)(H,132,160)(H,133,163)(H,134,157)(H,135,166)(H,140,141)(H,142,143)(H,144,145)/t56-,57-,64-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,86-,87-,88-/m0/s1	YGARCWJUVOXSDS-ZTNLKOGPSA-N	50197953	CHEMBL3980643	Endothelin-1 receptor			 0.670000							ChEMBL	10.1016/j.ejmech.2016.06.006	10.7270/Q2T155MF	27318985			Lepri, S; Goracci, L; Valeri, A; Cruciani, G	University of Perugia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197953&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			134157696	375978091		CHEMBL3980643					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50523918	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m0/s1	VYCMAAOURFJIHD-PJNXIOHISA-N	50197954	CHEBI:2965::CHEMBL314691	Endothelin-1 receptor			 0.620000							ChEMBL	10.1016/j.ejmech.2016.06.006	10.7270/Q2T155MF	27318985			Lepri, S; Goracci, L; Valeri, A; Cruciani, G	University of Perugia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197954&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			443289	375978092		CHEMBL314691			C11587		1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50523919	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 4.7							ChEMBL	10.1016/j.ejmech.2016.06.006	10.7270/Q2T155MF	27318985			Lepri, S; Goracci, L; Valeri, A; Cruciani, G	University of Perugia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50523922	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(OC)(C(F)(F)F)C(F)(F)F)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H23F6N5O7S/c1-42-18-6-3-4-7-19(18)45-20-21(36-23(22-34-12-5-13-35-22)37-24(20)44-15-14-39)38-46(40,41)17-10-8-16(9-11-17)25(43-2,26(28,29)30)27(31,32)33/h3-13,39H,14-15H2,1-2H3,(H,36,37,38)	ZVQCDWYQGWYVDS-UHFFFAOYSA-N	50197956	CHEMBL3918612	Endothelin-1 receptor			 693000							ChEMBL	10.1016/j.ejmech.2016.06.006	10.7270/Q2T155MF	27318985			Lepri, S; Goracci, L; Valeri, A; Cruciani, G	University of Perugia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197956&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			134139749	375978094		CHEMBL3918612					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50523923	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(F)(C(F)(F)F)C(F)(F)F)nc(nc1OCCO)-c1ncccn1	InChI=1S/C26H20F7N5O6S/c1-42-17-5-2-3-6-18(17)44-19-20(36-22(21-34-11-4-12-35-21)37-23(19)43-14-13-39)38-45(40,41)16-9-7-15(8-10-16)24(27,25(28,29)30)26(31,32)33/h2-12,39H,13-14H2,1H3,(H,36,37,38)	OCRSOSTUIAIWII-UHFFFAOYSA-N	50197957	CHEMBL3891334	Endothelin-1 receptor			 75							ChEMBL	10.1016/j.ejmech.2016.06.006	10.7270/Q2T155MF	27318985			Lepri, S; Goracci, L; Valeri, A; Cruciani, G	University of Perugia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197957&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			134136255	375978095		CHEMBL3891334					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029774	COc1nc(C)cnc1NS(=O)(=O)c1cccc(C(=O)NCCO)c1-c1ccc(CC(C)C)cc1	InChI=1S/C25H30N4O5S/c1-16(2)14-18-8-10-19(11-9-18)22-20(24(31)26-12-13-30)6-5-7-21(22)35(32,33)29-23-25(34-4)28-17(3)15-27-23/h5-11,15-16,30H,12-14H2,1-4H3,(H,26,31)(H,27,29)	MYCATVPVFLBZTM-UHFFFAOYSA-N	50421392	CHEMBL31544	Endothelin-1 receptor			 0.630957							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421392&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279141	164150267		CHEMBL31544			C04080	ZINC29206791	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029775	COCCNC(=O)c1cccc(c1-c1ccc(CC(C)C)cc1)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C25H29BrN4O5S/c1-16(2)14-17-8-10-18(11-9-17)22-19(24(31)27-12-13-34-3)6-5-7-20(22)36(32,33)30-23-25(35-4)29-21(26)15-28-23/h5-11,15-16H,12-14H2,1-4H3,(H,27,31)(H,28,30)	NBHBMAIIYLOAKT-UHFFFAOYSA-N	50421393	CHEMBL31592	Endothelin-1 receptor			 1.6							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421393&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279303	164150268		CHEMBL31592				ZINC29206992	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029776	COCCNC(=O)c1cccc(c1-c1ccc(CC(C)C)cc1)S(=O)(=O)Nc1ncc(C)nc1OC	InChI=1S/C26H32N4O5S/c1-17(2)15-19-9-11-20(12-10-19)23-21(25(31)27-13-14-34-4)7-6-8-22(23)36(32,33)30-24-26(35-5)29-18(3)16-28-24/h6-12,16-17H,13-15H2,1-5H3,(H,27,31)(H,28,30)	GXGUERYSOITQSY-UHFFFAOYSA-N	50421394	CHEMBL282187	Endothelin-1 receptor			 0.501187							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421394&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279554	164150269		CHEMBL282187				ZINC29209813	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029777	CCCCCNC(=O)c1cccc(c1-c1ccccc1)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C23H25BrN4O4S/c1-3-4-8-14-25-22(29)17-12-9-13-18(20(17)16-10-6-5-7-11-16)33(30,31)28-21-23(32-2)27-19(24)15-26-21/h5-7,9-13,15H,3-4,8,14H2,1-2H3,(H,25,29)(H,26,28)	RXJDSCNRKBPJDE-UHFFFAOYSA-N	50421395	CHEMBL32075	Endothelin-1 receptor			 4.0							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421395&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279172	164150270		CHEMBL32075				ZINC29204428	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029778	COc1nc(C)cnc1NS(=O)(=O)c1cccc(C(N)=O)c1-c1ccc(CC(C)C)cc1	InChI=1S/C23H26N4O4S/c1-14(2)12-16-8-10-17(11-9-16)20-18(21(24)28)6-5-7-19(20)32(29,30)27-22-23(31-4)26-15(3)13-25-22/h5-11,13-14H,12H2,1-4H3,(H2,24,28)(H,25,27)	VWGBCLUZCNNOOP-UHFFFAOYSA-N	50421396	CHEMBL285976	Endothelin-1 receptor			 1.00							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421396&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279398	164150271		CHEMBL285976				ZINC29208883	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029779	COc1nc(Br)cnc1NS(=O)(=O)c1cccc(C(=O)N(C)C)c1-c1ccc(CC(C)C)cc1	InChI=1S/C24H27BrN4O4S/c1-15(2)13-16-9-11-17(12-10-16)21-18(24(30)29(3)4)7-6-8-19(21)34(31,32)28-22-23(33-5)27-20(25)14-26-22/h6-12,14-15H,13H2,1-5H3,(H,26,28)	FPELOIHKLBXDFI-UHFFFAOYSA-N	50421397	CHEMBL286014	Endothelin-1 receptor			 1.00							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421397&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279294	164150272		CHEMBL286014				ZINC29206445	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029780	COc1nc(Br)cnc1NS(=O)(=O)c1ccccc1-c1ccc(CC(C)C)cc1	InChI=1S/C21H22BrN3O3S/c1-14(2)12-15-8-10-16(11-9-15)17-6-4-5-7-18(17)29(26,27)25-20-21(28-3)24-19(22)13-23-20/h4-11,13-14H,12H2,1-3H3,(H,23,25)	MGBBQRGEPMWHTQ-UHFFFAOYSA-N	50421398	CHEMBL287581	Endothelin-1 receptor			 40							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421398&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18704814	164150273		CHEMBL287581				ZINC29207901	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029781	COc1nc(Br)cnc1NS(=O)(=O)c1ccccc1-c1ccccc1	InChI=1S/C17H14BrN3O3S/c1-24-17-16(19-11-15(18)20-17)21-25(22,23)14-10-6-5-9-13(14)12-7-3-2-4-8-12/h2-11H,1H3,(H,19,21)	BOJJKQYBPRXVFI-UHFFFAOYSA-N	50421399	CHEMBL285512	Endothelin-1 receptor			 32							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421399&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18704821	164150274		CHEMBL285512				ZINC29206956	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029782	COc1nc(Br)cnc1NS(=O)(=O)c1cccc(C(N)=O)c1-c1ccccc1	InChI=1S/C18H15BrN4O4S/c1-27-18-17(21-10-14(19)22-18)23-28(25,26)13-9-5-8-12(16(20)24)15(13)11-6-3-2-4-7-11/h2-10H,1H3,(H2,20,24)(H,21,23)	JGSZTZRKVIBCSK-UHFFFAOYSA-N	50421400	CHEMBL32512	Endothelin-1 receptor			 40							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421400&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279237	164150275		CHEMBL32512				ZINC29206117	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029783	CNC(=O)c1cccc(c1-c1ccc(CC(C)C)cc1)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C23H25BrN4O4S/c1-14(2)12-15-8-10-16(11-9-15)20-17(22(29)25-3)6-5-7-18(20)33(30,31)28-21-23(32-4)27-19(24)13-26-21/h5-11,13-14H,12H2,1-4H3,(H,25,29)(H,26,28)	JIASFQMIVFBCTK-UHFFFAOYSA-N	50421401	CHEMBL32572	Endothelin-1 receptor			 1.3							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421401&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279296	164150276		CHEMBL32572				ZINC29206453	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029784	COc1nc(Br)cnc1NS(=O)(=O)c1cccc(C(N)=O)c1-c1ccc(CC(C)C)cc1	InChI=1S/C22H23BrN4O4S/c1-13(2)11-14-7-9-15(10-8-14)19-16(20(24)28)5-4-6-17(19)32(29,30)27-21-22(31-3)26-18(23)12-25-21/h4-10,12-13H,11H2,1-3H3,(H2,24,28)(H,25,27)	UKZIIQJFSMYSEP-UHFFFAOYSA-N	50421402	CHEMBL31763	Endothelin-1 receptor			 0.794328							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421402&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279316	164150277		CHEMBL31763				ZINC29208915	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029785	COc1nc(C)cnc1NS(=O)(=O)c1cccc(C(=O)N(C)C)c1-c1ccc(CC(C)C)cc1	InChI=1S/C25H30N4O4S/c1-16(2)14-18-10-12-19(13-11-18)22-20(25(30)29(4)5)8-7-9-21(22)34(31,32)28-23-24(33-6)27-17(3)15-26-23/h7-13,15-16H,14H2,1-6H3,(H,26,28)	ZKLQLUDZFNFIOA-UHFFFAOYSA-N	50421403	CHEMBL31324	Endothelin-1 receptor			 2.5							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421403&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279295	164150278		CHEMBL31324				ZINC29206449	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029786	CCCCCNC(=O)c1cccc(c1-c1ccc(CC(C)C)cc1)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C27H33BrN4O4S/c1-5-6-7-15-29-26(33)21-9-8-10-22(24(21)20-13-11-19(12-14-20)16-18(2)3)37(34,35)32-25-27(36-4)31-23(28)17-30-25/h8-14,17-18H,5-7,15-16H2,1-4H3,(H,29,33)(H,30,32)	CJZFVLUVSQCXNF-UHFFFAOYSA-N	50421404	CHEMBL32574	Endothelin-1 receptor			 200							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421404&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279140	164150279		CHEMBL32574				ZINC29207130	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029787	CNC(=O)c1cccc(c1-c1ccc(CC(C)C)cc1)S(=O)(=O)Nc1ncc(C)nc1OC	InChI=1S/C24H28N4O4S/c1-15(2)13-17-9-11-18(12-10-17)21-19(23(29)25-4)7-6-8-20(21)33(30,31)28-22-24(32-5)27-16(3)14-26-22/h6-12,14-15H,13H2,1-5H3,(H,25,29)(H,26,28)	LUGPNDHPEZLAMX-UHFFFAOYSA-N	50421405	CHEMBL32066	Endothelin-1 receptor			 0.501187							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421405&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11754394	164150280		CHEMBL32066				ZINC00602178	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51029788	CNC(=O)c1cccc(c1-c1ccccc1)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C19H17BrN4O4S/c1-21-18(25)13-9-6-10-14(16(13)12-7-4-3-5-8-12)29(26,27)24-17-19(28-2)23-15(20)11-22-17/h3-11H,1-2H3,(H,21,25)(H,22,24)	JYFKMUUBEICGRX-UHFFFAOYSA-N	50421406	CHEMBL31696	Endothelin-1 receptor			 40							ChEMBL	10.1016/S0960-894X(97)00228-X	10.7270/Q2NS0W6W				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421406&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44279173	164150281		CHEMBL31696				ZINC29204497	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032439	CCOc1ccc(NS(=O)(=O)c2cccc3c(cccc23)N(C)C)nn1	InChI=1S/C18H20N4O3S/c1-4-25-18-12-11-17(19-20-18)21-26(23,24)16-10-6-7-13-14(16)8-5-9-15(13)22(2)3/h5-12H,4H2,1-3H3,(H,19,21)	QWTLDQHYZZGSAB-UHFFFAOYSA-N	50422232	CHEMBL269237	Endothelin-1 receptor			 3981							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422232&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11793650	164151107		CHEMBL269237				ZINC13761363	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032440	COc1ccc(NS(=O)(=O)c2cccc3c(cccc23)N(C)C)nn1	InChI=1S/C17H18N4O3S/c1-21(2)14-8-4-7-13-12(14)6-5-9-15(13)25(22,23)20-16-10-11-17(24-3)19-18-16/h4-11H,1-3H3,(H,18,20)	DMZKKCRZCZZBAT-UHFFFAOYSA-N	50422233	CHEMBL6624	Endothelin-1 receptor			 316							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422233&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10832243	164151108		CHEMBL6624				ZINC13761362	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032441	COc1nc(Cl)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C	InChI=1S/C17H17ClN4O3S/c1-22(2)13-8-4-7-12-11(13)6-5-9-14(12)26(23,24)21-16-17(25-3)20-15(18)10-19-16/h4-10H,1-3H3,(H,19,21)	ZEICTPGVQAZONR-UHFFFAOYSA-N	50422234	CHEMBL6412	Endothelin-1 receptor			 10.0							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422234&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10475644	164151109		CHEMBL6412				ZINC00601988	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032442	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)[nH]c1=O	InChI=1S/C16H15BrN4O3S/c1-21(2)12-7-3-6-11-10(12)5-4-8-13(11)25(23,24)20-15-16(22)19-14(17)9-18-15/h3-9H,1-2H3,(H,18,20)(H,19,22)	QGWCWMMDAPXEJF-UHFFFAOYSA-N	50422235	CHEMBL6647	Endothelin-1 receptor			 5012							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740942	164151110		CHEMBL6647				ZINC13761370	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032443	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(C)cn1	InChI=1S/C18H19N3O2S/c1-13-10-11-18(19-12-13)20-24(22,23)17-9-5-6-14-15(17)7-4-8-16(14)21(2)3/h4-12H,1-3H3,(H,19,20)	YDPDSONKGZIZJX-UHFFFAOYSA-N	50422236	CHEMBL6463	Endothelin-1 receptor			 1585							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422236	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422236&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5017966	164151111		CHEMBL6463				ZINC08696915	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032444	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)cn1	InChI=1S/C17H16ClN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-17-10-9-12(18)11-19-17/h3-11H,1-2H3,(H,19,20)	RSBSFRHJBBDZEW-UHFFFAOYSA-N	50422237	CHEMBL266315	Endothelin-1 receptor			 1995							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422237&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9885296	164151112		CHEMBL266315				ZINC00835940	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032445	COc1nc(Br)cnc1NS(=O)(=O)c1cccc2ccccc12	InChI=1S/C15H12BrN3O3S/c1-22-15-14(17-9-13(16)18-15)19-23(20,21)12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,17,19)	SNZBYFGGSSWJKY-UHFFFAOYSA-N	50422238	CHEMBL6576	Endothelin-1 receptor			 1995							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422238&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10786783	164151113		CHEMBL6576				ZINC13761377	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032446	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncccn1	InChI=1S/C16H16N4O2S/c1-20(2)14-8-3-7-13-12(14)6-4-9-15(13)23(21,22)19-16-17-10-5-11-18-16/h3-11H,1-2H3,(H,17,18,19)	MSQQFEVXXADDJG-UHFFFAOYSA-N	50422239	CHEMBL6468	Endothelin-1 receptor			 6310							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422239&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10496523	164151114		CHEMBL6468				ZINC13761356	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032447	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)cn1	InChI=1S/C17H16BrN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-17-10-9-12(18)11-19-17/h3-11H,1-2H3,(H,19,20)	CLEFKCFLXWSUFJ-UHFFFAOYSA-N	50422240	CHEMBL6411	Endothelin-1 receptor			 1585							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422240&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5018984	164151115		CHEMBL6411				ZINC00835942	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032448	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1nnc(Cl)cc1C	InChI=1S/C17H17ClN4O2S/c1-11-10-16(18)19-20-17(11)21-25(23,24)15-9-5-6-12-13(15)7-4-8-14(12)22(2)3/h4-10H,1-3H3,(H,20,21)	WTGLGALNVFXVHG-UHFFFAOYSA-N	50422241	CHEMBL415106	Endothelin-1 receptor			 398							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422241&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10833400	164151116		CHEMBL415106				ZINC00592398	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032449	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)cc1	InChI=1S/C18H17BrN2O2S/c1-21(2)17-7-3-6-16-15(17)5-4-8-18(16)24(22,23)20-14-11-9-13(19)10-12-14/h3-12,20H,1-2H3	RROBKFJDPRVGFW-UHFFFAOYSA-N	50422242	CHEMBL6400	Endothelin-1 receptor			 3162							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422242&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10692649	164151117		CHEMBL6400				ZINC13761355	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032450	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)nn1	InChI=1S/C16H15BrN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-9-15(17)18-19-16/h3-10H,1-2H3,(H,19,20)	LAGNMQASQNSBPF-UHFFFAOYSA-N	50422243	CHEMBL6297	Endothelin-1 receptor			 251							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422243&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740139	164151118		CHEMBL6297				ZINC13761361	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032451	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Br)cn1	InChI=1S/C16H15BrN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-18-15(17)9-19-16/h3-10H,1-2H3,(H,19,20)	DFVPVSOUYKGHAX-UHFFFAOYSA-N	50422244	CHEMBL268339	Endothelin-1 receptor			 126							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422244&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10645066	164151119		CHEMBL268339				ZINC13761367	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032452	CCOc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C	InChI=1S/C18H19BrN4O3S/c1-4-26-18-17(20-11-16(19)21-18)22-27(24,25)15-10-6-7-12-13(15)8-5-9-14(12)23(2)3/h5-11H,4H2,1-3H3,(H,20,22)	MLJGSVQFLSTLQF-UHFFFAOYSA-N	50422245	CHEMBL6588	Endothelin-1 receptor			 501							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422245&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10671298	164151120		CHEMBL6588				ZINC13761372	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032453	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Cl)cn1	InChI=1S/C16H15ClN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-18-15(17)9-19-16/h3-10H,1-2H3,(H,19,20)	QVIHMHNAXFQPQO-UHFFFAOYSA-N	50422246	CHEMBL6553	Endothelin-1 receptor			 158							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422246&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10832511	164151121		CHEMBL6553				ZINC13761366	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032454	CCc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C	InChI=1S/C18H19BrN4O2S/c1-4-14-18(20-11-17(19)21-14)22-26(24,25)16-10-6-7-12-13(16)8-5-9-15(12)23(2)3/h5-11H,4H2,1-3H3,(H,20,22)	AXNXKWXEPIXRQC-UHFFFAOYSA-N	50422247	CHEMBL6543	Endothelin-1 receptor			 2512							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422247&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10646522	164151122		CHEMBL6543				ZINC13761369	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032455	COc1nc(Br)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C	InChI=1S/C17H17BrN4O3S/c1-22(2)13-8-4-7-12-11(13)6-5-9-14(12)26(23,24)21-16-17(25-3)20-15(18)10-19-16/h4-10H,1-3H3,(H,19,21)	JDNYZAWNISHXJL-UHFFFAOYSA-N	50422248	CHEMBL6800	Endothelin-1 receptor			 63							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422248&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10646616	164151123		CHEMBL6800				ZINC13761371	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032456	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)nc1	InChI=1S/C17H16BrN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-12-9-10-17(18)19-11-12/h3-11,20H,1-2H3	HFDGZOCJFKXXRM-UHFFFAOYSA-N	50422249	CHEMBL266277	Endothelin-1 receptor			 251							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422249&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10787482	164151124		CHEMBL266277				ZINC13761353	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032457	COc1nc(C)cnc1NS(=O)(=O)c1cccc2c(cccc12)N(C)C	InChI=1S/C18H20N4O3S/c1-12-11-19-17(18(20-12)25-4)21-26(23,24)16-10-6-7-13-14(16)8-5-9-15(13)22(2)3/h5-11H,1-4H3,(H,19,21)	OWLNCBVMDZBDPC-UHFFFAOYSA-N	50422250	CHEMBL268174	Endothelin-1 receptor			 7.9							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422250&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10667000	164151125		CHEMBL268174				ZINC13761373	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032458	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cc(C)c(Cl)nn1	InChI=1S/C17H17ClN4O2S/c1-11-10-16(19-20-17(11)18)21-25(23,24)15-9-5-6-12-13(15)7-4-8-14(12)22(2)3/h4-10H,1-3H3,(H,19,21)	SYRDOLQNAYZUOF-UHFFFAOYSA-N	50422251	CHEMBL6660	Endothelin-1 receptor			 5012							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422251&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10595728	164151126		CHEMBL6660				ZINC00592396	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032459	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)cc1	InChI=1S/C18H17ClN2O2S/c1-21(2)17-7-3-6-16-15(17)5-4-8-18(16)24(22,23)20-14-11-9-13(19)10-12-14/h3-12,20H,1-2H3	TWRCAICAMBKPHB-UHFFFAOYSA-N	50422252	CHEMBL6778	Endothelin-1 receptor			 7943							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422252&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3847484	164151127		CHEMBL6778				ZINC13761354	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032460	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(C)cn1	InChI=1S/C17H18N4O2S/c1-12-10-19-17(11-18-12)20-24(22,23)16-9-5-6-13-14(16)7-4-8-15(13)21(2)3/h4-11H,1-3H3,(H,19,20)	KMWSOKYMPGSVHO-UHFFFAOYSA-N	50422253	CHEMBL6583	Endothelin-1 receptor			 1259							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422253&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10593411	164151128		CHEMBL6583				ZINC13761365	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032461	CCN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C18H19BrN4O3S/c1-4-23(2)14-9-5-8-13-12(14)7-6-10-15(13)27(24,25)22-17-18(26-3)21-16(19)11-20-17/h5-11H,4H2,1-3H3,(H,20,22)	LTBGGVYTZUDEIJ-UHFFFAOYSA-N	50422254	CHEMBL6785	Endothelin-1 receptor			 13							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422254&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10623465	164151129		CHEMBL6785				ZINC13761376	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032462	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)cn1	InChI=1S/C16H15BrN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-16-18-9-11(17)10-19-16/h3-10H,1-2H3,(H,18,19,20)	KBJRQIMFXHNPEQ-UHFFFAOYSA-N	50422255	CHEMBL6630	Endothelin-1 receptor			 1995							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422255&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740137	164151130		CHEMBL6630				ZINC13761358	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032463	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(C)nn1	InChI=1S/C17H18N4O2S/c1-12-10-11-17(19-18-12)20-24(22,23)16-9-5-6-13-14(16)7-4-8-15(13)21(2)3/h4-11H,1-3H3,(H,19,20)	FMSIUEZKWYHEOF-UHFFFAOYSA-N	50422256	CHEMBL268387	Endothelin-1 receptor			 1585							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422256&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10569313	164151131		CHEMBL268387				ZINC13761360	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032464	CNc1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C16H15BrN4O3S/c1-18-12-7-3-6-11-10(12)5-4-8-13(11)25(22,23)21-15-16(24-2)20-14(17)9-19-15/h3-9,18H,1-2H3,(H,19,21)	XDULZYJHZGTMOM-UHFFFAOYSA-N	50422257	CHEMBL6555	Endothelin-1 receptor			 16							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422257&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740943	164151132		CHEMBL6555				ZINC13761374	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032465	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnccn1	InChI=1S/C16H16N4O2S/c1-20(2)14-7-3-6-13-12(14)5-4-8-15(13)23(21,22)19-16-11-17-9-10-18-16/h3-11H,1-2H3,(H,18,19)	NRLWXFWPCBEKRI-UHFFFAOYSA-N	50422258	CHEMBL6399	Endothelin-1 receptor			 1000							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422258&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10568280	164151133		CHEMBL6399				ZINC13761364	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032466	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(I)cn1	InChI=1S/C17H16IN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-17-10-9-12(18)11-19-17/h3-11H,1-2H3,(H,19,20)	AVIZINDXBJTFCL-UHFFFAOYSA-N	50422259	CHEMBL266684	Endothelin-1 receptor			 5012							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422259&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10789830	164151134		CHEMBL266684				ZINC13761351	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032467	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Br)c(C)n1	InChI=1S/C18H18BrN3O2S/c1-12-15(19)10-11-18(20-12)21-25(23,24)17-9-5-6-13-14(17)7-4-8-16(13)22(2)3/h4-11H,1-3H3,(H,20,21)	QBKBVEQZXPNGQC-UHFFFAOYSA-N	50422260	CHEMBL6566	Endothelin-1 receptor			 10000							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422260&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			3765218	164151135		CHEMBL6566				ZINC08697199	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032468	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)nc1	InChI=1S/C17H16ClN3O2S/c1-21(2)15-7-3-6-14-13(15)5-4-8-16(14)24(22,23)20-12-9-10-17(18)19-11-12/h3-11,20H,1-2H3	KWCGGSGQFPVERL-UHFFFAOYSA-N	50422261	CHEMBL415292	Endothelin-1 receptor			 1259							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422261&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11792960	164151136		CHEMBL415292				ZINC13761352	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032469	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Cl)cn1	InChI=1S/C16H15ClN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-16-18-9-11(17)10-19-16/h3-10H,1-2H3,(H,18,19,20)	KLFNCMDJCYONOH-UHFFFAOYSA-N	50422262	CHEMBL6433	Endothelin-1 receptor			 1585							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422262&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10690058	164151137		CHEMBL6433				ZINC13761357	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032470	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1C	InChI=1S/C17H17BrN4O2S/c1-11-17(19-10-16(18)20-11)21-25(23,24)15-9-5-6-12-13(15)7-4-8-14(12)22(2)3/h4-10H,1-3H3,(H,19,21)	WONYSUAAXSMWMV-UHFFFAOYSA-N	50422263	CHEMBL6382	Endothelin-1 receptor			 631							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422263&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10550094	164151138		CHEMBL6382				ZINC13761368	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032471	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1onc(C)c1C	InChI=1S/C17H19N3O3S/c1-11-12(2)18-23-17(11)19-24(21,22)16-10-6-7-13-14(16)8-5-9-15(13)20(3)4/h5-10,19H,1-4H3	MJRGSRRZKSJHOE-UHFFFAOYSA-N	50034435	5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-2,3-dihydro-oxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide (BMS 182874)::BMS-182874::CHEMBL267458	Endothelin-1 receptor			 50							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034435&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122272	103942636		CHEMBL267458				ZINC00005803	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032472	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ccc(Cl)nn1	InChI=1S/C16H15ClN4O2S/c1-21(2)13-7-3-6-12-11(13)5-4-8-14(12)24(22,23)20-16-10-9-15(17)18-19-16/h3-10H,1-2H3,(H,19,20)	CIYDSKLFHZROHZ-UHFFFAOYSA-N	50422264	CHEMBL6761	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422264&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11793037	164151139		CHEMBL6761				ZINC00600415	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032473	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)cc1C	InChI=1S/C18H18BrN3O2S/c1-12-10-13(19)11-20-18(12)21-25(23,24)17-9-5-6-14-15(17)7-4-8-16(14)22(2)3/h4-11H,1-3H3,(H,20,21)	YMGNXXUWTUHJRZ-UHFFFAOYSA-N	50422265	CHEMBL268116	Endothelin-1 receptor			 316							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422265&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10645779	164151140		CHEMBL268116				ZINC00600659	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032474	CN(C)c1cccc2c(cccc12)S(=O)(=O)Nc1cnc(Br)nc1	InChI=1S/C16H15BrN4O2S/c1-21(2)14-7-3-6-13-12(14)5-4-8-15(13)24(22,23)20-11-9-18-16(17)19-10-11/h3-10,20H,1-2H3	PBZQPEYJZSYMNV-UHFFFAOYSA-N	50422266	CHEMBL7019	Endothelin-1 receptor			 631							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422266&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10740138	164151141		CHEMBL7019				ZINC13761359	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51032475	CCNc1cccc2c(cccc12)S(=O)(=O)Nc1ncc(Br)nc1OC	InChI=1S/C17H17BrN4O3S/c1-3-19-13-8-4-7-12-11(13)6-5-9-14(12)26(23,24)22-16-17(25-2)21-15(18)10-20-16/h4-10,19H,3H2,1-2H3,(H,20,22)	YDPOXHCJDBMWLW-UHFFFAOYSA-N	50422267	CHEMBL263079	Endothelin-1 receptor			 2.5							ChEMBL	10.1021/jm9604585	10.7270/Q25H7HKT	9083490			Bradbury, RH; Bath, C; Butlin, RJ; Dennis, M; Heys, C; Hunt, SJ; James, R; Mortlock, AA; Sumner, NF; Tang, EK; Telford, B; Whiting, E; Wilson, C	Zeneca Pharmaceuticals	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50422267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50422267&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10670600	164151142		CHEMBL263079				ZINC13761375	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006864	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C31H35N7O8S/c1-21(2)22-11-12-26(33-20-22)47(40,41)37-28-27(46-24-9-5-4-8-23(24)42-3)29(36-30(35-28)38-14-16-43-17-15-38)44-18-19-45-31(39)34-25-10-6-7-13-32-25/h4-13,20-21H,14-19H2,1-3H3,(H,32,34,39)(H,35,36,37)	MXLGWPUNPPHJQC-UHFFFAOYSA-N	50290043	CHEMBL72037::Pyridin-2-yl-carbamic acid 2-[6-(5-isopropyl-pyridine-2-sulfonylamino)-5-(2-methoxy-phenoxy)-2-morpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290043&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9809919	104131614		CHEMBL72037				ZINC03977732	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50013864	C\C=C\C=C\C=C\C(=O)O[C@@H]1C=C2COC(=O)[C@]2(O)[C@@]2(C)CCCC(C)(C)C12	InChI=1S/C23H30O5/c1-5-6-7-8-9-11-18(24)28-17-14-16-15-27-20(25)23(16,26)22(4)13-10-12-21(2,3)19(17)22/h5-9,11,14,17,19,26H,10,12-13,15H2,1-4H3/b6-5+,8-7+,11-9+/t17-,19?,22+,23+/m1/s1	DPTZOOXIEWHODB-CMFMVBRPSA-N	50088848	(2E,4E,6E)-Octa-2,4,6-trienoic acid (5R,9aS,9bS)-9b-hydroxy-6,6,9a-trimethyl-1-oxo-1,3,5,5a,6,7,8,9,9a,9b-decahydro-naphtho[1,2-c]furan-5-yl ester::CHEMBL173059	Endothelin-1 receptor			 135000							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088848&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383592	103987719		CHEMBL173059				ZINC28011393	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158584	C\C=C\C=C\C(=O)O[C@@H]1C=C2COC(O)[C@]2(O)[C@@]2(C)CCCC(C)(C)C12	InChI=1S/C21H30O5/c1-5-6-7-9-16(22)26-15-12-14-13-25-18(23)21(14,24)20(4)11-8-10-19(2,3)17(15)20/h5-7,9,12,15,17-18,23-24H,8,10-11,13H2,1-4H3/b6-5+,9-7+/t15-,17?,18?,20+,21+/m1/s1	UJVJESYKEHAJNS-GJYYWCKTSA-N	50088850	(2E,4E)-Hexa-2,4-dienoic acid (5R,9aS,9bS)-1,9b-dihydroxy-6,6,9a-trimethyl-1,3,5,5a,6,7,8,9,9a,9b-decahydro-naphtho[1,2-c]furan-5-yl ester::CHEMBL353502	Endothelin-1 receptor			>250000							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088850&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383536	103987721		CHEMBL353502				ZINC28001169	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50158585	C\C=C\C=C\C=C\C(=O)O[C@@H]1C=C2COC(O)[C@]2(O)[C@@]2(C)CCCC(C)(C)C12	InChI=1S/C23H32O5/c1-5-6-7-8-9-11-18(24)28-17-14-16-15-27-20(25)23(16,26)22(4)13-10-12-21(2,3)19(17)22/h5-9,11,14,17,19-20,25-26H,10,12-13,15H2,1-4H3/b6-5+,8-7+,11-9+/t17-,19?,20?,22+,23+/m1/s1	BIBMODCOJDZAGU-ROOWPLTDSA-N	50088849	(2E,4E,6E)-Octa-2,4,6-trienoic acid (5R,9aS,9bS)-1,9b-dihydroxy-6,6,9a-trimethyl-1,3,5,5a,6,7,8,9,9a,9b-decahydro-naphtho[1,2-c]furan-5-yl ester::CHEMBL170335	Endothelin-1 receptor			 62000							ChEMBL	10.1016/s0960-894x(00)00136-0	10.7270/Q2862FNT	10853654			Kraus, GA; Wang, X	Iowa State University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088849&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44383537	103987720		CHEMBL170335				ZINC28001685	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480081	C(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C21H15NO2/c1-3-7-18-15(5-1)17(16-6-2-4-8-19(16)22-18)11-14-9-10-20-21(12-14)24-13-23-20/h1-10,12H,11,13H2	ZNIQDBVATXDCBV-UHFFFAOYSA-N	50288540	9-Benzo[1,3]dioxol-5-ylmethyl-acridine::CHEMBL99963	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288540&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332745	104130111		CHEMBL99963				ZINC26750931	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480092	COC(=O)C(c1ccc2OCOc2c1)c1cc(nc2ccccc12)-c1ccccc1	InChI=1S/C25H19NO4/c1-28-25(27)24(17-11-12-22-23(13-17)30-15-29-22)19-14-21(16-7-3-2-4-8-16)26-20-10-6-5-9-18(19)20/h2-14,24H,15H2,1H3	JHTFPOOWJFSFAY-UHFFFAOYSA-N	50288553	Benzo[1,3]dioxol-5-yl-(2-phenyl-quinolin-4-yl)-acetic acid methyl ester::CHEMBL103631	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288553&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332775	104130124		CHEMBL103631				ZINC26819636	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480096	COC(=O)C(C(c1ccccc1)c1ccccc1)c1ccc2OCOc2c1	InChI=1S/C23H20O4/c1-25-23(24)22(18-12-13-19-20(14-18)27-15-26-19)21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-14,21-22H,15H2,1H3	PFQISMRUXMIYPF-UHFFFAOYSA-N	50288533	2-Benzo[1,3]dioxol-5-yl-3,3-diphenyl-propionic acid methyl ester::CHEMBL103969	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288533&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332856	104130104		CHEMBL103969				ZINC26820221	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480102	OCC(c1ccc2OCOc2c1)c1c2ccccc2nc2ccccc12	InChI=1S/C22H17NO3/c24-12-17(14-9-10-20-21(11-14)26-13-25-20)22-15-5-1-3-7-18(15)23-19-8-4-2-6-16(19)22/h1-11,17,24H,12-13H2	RVEUDTXJLDUWSX-UHFFFAOYSA-N	50288548	2-Acridin-9-yl-2-benzo[1,3]dioxol-5-yl-ethanol::CHEMBL100795	Endothelin-1 receptor			 10000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288548&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44213651	104130119		CHEMBL100795				ZINC11689465	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50480104	Clc1ccc(COC(=O)C(c2ccc3OCOc3c2)c2c3ccccc3nc3ccccc23)cc1	InChI=1S/C29H20ClNO4/c30-20-12-9-18(10-13-20)16-33-29(32)27(19-11-14-25-26(15-19)35-17-34-25)28-21-5-1-3-7-23(21)31-24-8-4-2-6-22(24)28/h1-15,27H,16-17H2	BDQKQZBSECLBLP-UHFFFAOYSA-N	50288558	Acridin-9-yl-benzo[1,3]dioxol-5-yl-acetic acid 4-chloro-benzyl ester::CHEMBL101292	Endothelin-1 receptor			>25000							ChEMBL	10.1016/S0960-894X(96)00551-3	10.7270/Q26D5SZK				Cheng, XM; Lee, C; Klutchko, S; Winters, T; Reynolds, EE; Welch, KM; Flynn, MA; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50288558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50288558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332650	104130129		CHEMBL101292				ZINC26750945	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027461	CCC(CO)Cc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C31H36N2O6/c1-5-18(15-34)12-20-13-21(37-4)7-8-22(20)28-29(31(35)36)27(19-6-10-24-25(14-19)39-16-38-24)23-9-11-26(32-17(2)3)33-30(23)28/h6-11,13-14,17-18,27-29,34H,5,12,15-16H2,1-4H3,(H,32,33)(H,35,36)/t18?,27-,28-,29+/m0/s1	CICVRMZHTUTILV-NBNHAXFZSA-N	50141458	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxymethyl-butyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL411925	Endothelin-1 receptor			 0.011							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141458&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284287	104030917		CHEMBL411925				ZINC29252205	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50027465	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(OC(C)CO)c1	InChI=1S/C29H32N2O7/c1-15(2)30-24-10-8-20-25(17-5-9-21-23(11-17)37-14-36-21)27(29(33)34)26(28(20)31-24)19-7-6-18(35-4)12-22(19)38-16(3)13-32/h5-12,15-16,25-27,32H,13-14H2,1-4H3,(H,30,31)(H,33,34)/t16?,25-,26-,27+/m0/s1	WERWDDKHJRXHAF-RNGUFSMASA-N	50141467	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-hydroxy-1-methyl-ethoxy)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL289216	Endothelin-1 receptor			 0.057							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141467&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284041	104030926		CHEMBL289216				ZINC29318630	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259847	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(C)C(=O)N(C)C)c1	InChI=1S/C32H37N3O6/c1-17(2)33-26-12-10-23-27(19-7-11-24-25(15-19)41-16-40-24)29(32(37)38)28(30(23)34-26)22-9-8-21(39-6)14-20(22)13-18(3)31(36)35(4)5/h7-12,14-15,17-18,27-29H,13,16H2,1-6H3,(H,33,34)(H,37,38)/t18?,27-,28-,29+/m0/s1	IDRPGYTWDRQQOE-NBNHAXFZSA-N	50141468	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2-dimethylcarbamoyl-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL287683	Endothelin-1 receptor			 0.024							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141468&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284288	104030927		CHEMBL287683				ZINC29252219	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259853	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(O)CO)c1	InChI=1S/C29H32N2O7/c1-15(2)30-24-9-7-21-25(16-4-8-22-23(12-16)38-14-37-22)27(29(34)35)26(28(21)31-24)20-6-5-19(36-3)11-17(20)10-18(33)13-32/h4-9,11-12,15,18,25-27,32-33H,10,13-14H2,1-3H3,(H,30,31)(H,34,35)/t18?,25-,26-,27+/m0/s1	HAZBSXKXEZHGFW-XZYOMFCLSA-N	50141461	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(2,3-dihydroxy-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL286621	Endothelin-1 receptor			 0.048							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141461&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284437	104030920		CHEMBL286621				ZINC29251677	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259863	COc1ccc([C@H]2[C@@H]([C@H](c3ccc(NC(C)C)nc23)c2ccc3OCOc3c2)C(O)=O)c(CC(C)CO)c1	InChI=1S/C30H34N2O6/c1-16(2)31-25-10-8-22-26(18-5-9-23-24(13-18)38-15-37-23)28(30(34)35)27(29(22)32-25)21-7-6-20(36-4)12-19(21)11-17(3)14-33/h5-10,12-13,16-17,26-28,33H,11,14-15H2,1-4H3,(H,31,32)(H,34,35)/t17?,26-,27-,28+/m0/s1	KBHRSNOQJNLUNL-DULCMVPVSA-N	50141460	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-7-[2-(3-hydroxy-2-methyl-propyl)-4-methoxy-phenyl]-2-isopropylamino-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL288247	Endothelin-1 receptor			 0.059							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141460&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284115	104030919		CHEMBL288247				ZINC29253550	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50259886	COCC(C)Cc1cc(OC)ccc1[C@H]1[C@@H]([C@H](c2ccc(NC(C)C)nc12)c1ccc2OCOc2c1)C(O)=O	InChI=1S/C31H36N2O6/c1-17(2)32-26-11-9-23-27(19-6-10-24-25(14-19)39-16-38-24)29(31(34)35)28(30(23)33-26)22-8-7-21(37-5)13-20(22)12-18(3)15-36-4/h6-11,13-14,17-18,27-29H,12,15-16H2,1-5H3,(H,32,33)(H,34,35)/t18?,27-,28-,29+/m0/s1	HWNXCQQEFQWPHX-NBNHAXFZSA-N	50141472	(5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-isopropylamino-7-[4-methoxy-2-(3-methoxy-2-methyl-propyl)-phenyl]-6,7-dihydro-5H-[1]pyrindine-6-carboxylic acid::CHEMBL289634	Endothelin-1 receptor			 0.011							ChEMBL	10.1016/j.bmcl.2004.01.008	10.7270/Q23R0SB4	15006391			Takahashi, H; Ohtake, N; Sakamoto, T; Iino, T; Kawanishi, N; Nakamura, M; Yoshizumi, T; Niiyama, K; Ozaki, S; Okada, H; Kano, A; Takahashi, H; Ishii, Y; Okada, M; Saito, M; Sawazaki, Y; Hayama, T; Nishikibe, M	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141472&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44284405	104030931		CHEMBL289634				ZINC38158217	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50063086	COc1ccc(cc1)C1(OC(=O)N[C@@H](C)c2cccc3ccccc23)OC(=O)C(=C1Cc1cc(OC)c(OC)c(OC)c1)c1ccc2OCOc2c1	InChI=1S/C41H37NO10/c1-24(30-12-8-10-26-9-6-7-11-31(26)30)42-40(44)52-41(28-14-16-29(45-2)17-15-28)32(19-25-20-35(46-3)38(48-5)36(21-25)47-4)37(39(43)51-41)27-13-18-33-34(22-27)50-23-49-33/h6-18,20-22,24H,19,23H2,1-5H3,(H,42,44)/t24-,41?/m0/s1	FFJYBEOEJYDRNP-JDRJKRQWSA-N	50290979	((S)-1-Naphthalen-1-yl-ethyl)-carbamic acid 4-benzo[1,3]dioxol-5-yl-2-(4-methoxy-phenyl)-5-oxo-3-(3,4,5-trimethoxy-benzyl)-2,5-dihydro-furan-2-yl ester::CHEMBL322920	Endothelin-1 receptor			 2.00							ChEMBL	10.1016/S0960-894X(97)00002-4	10.7270/Q2B8584G				Patt, WC; Reisdorph, BR; Repine, JT; Doherty, AM; Haleen, SJ; Walker, DM; Welch, KM; Flynn, MA; Hallak, H; Reyner, EL; Stewart, BH	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290979&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44332842	104132531		CHEMBL322920				ZINC26825975	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006865	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 80							ChEMBL	10.1016/S0960-894X(97)00400-9	10.7270/Q2WQ049M				Neidhart, W; Breu, V; Burri, K; Clozel, M; Hirth, G; Klinkhammer, U; Giller, T; Ramuz, H	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50476196	C[C@@H](O)[C@H]1NC(=O)CNC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC(N)=O)NC(=O)CNC(=O)[C@H](CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(O)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](C)NC1=O	InChI=1S/C103H115N23O23/c1-54-102(147)126-35-15-26-83(126)100(145)123-81(91(136)110-51-87(133)115-79(44-84(104)130)98(143)120-77(41-61-48-108-70-24-13-10-21-67(61)70)97(142)121-78(43-63-50-106-53-112-63)90(135)111-52-88(134)125-89(55(2)127)101(146)113-54)46-86(132)114-76(40-60-47-107-69-23-12-9-20-66(60)69)96(141)118-72(36-56-16-5-3-6-17-56)92(137)116-73(37-57-18-7-4-8-19-57)94(139)122-80(45-85(105)131)99(144)119-74(38-58-27-31-64(128)32-28-58)93(138)117-75(39-59-29-33-65(129)34-30-59)95(140)124-82(103(148)149)42-62-49-109-71-25-14-11-22-68(62)71/h3-14,16-25,27-34,47-50,53-55,72-83,89,107-109,127-129H,15,26,35-46,51-52H2,1-2H3,(H2,104,130)(H2,105,131)(H,106,112)(H,110,136)(H,111,135)(H,113,146)(H,114,132)(H,115,133)(H,116,137)(H,117,138)(H,118,141)(H,119,144)(H,120,143)(H,121,142)(H,122,139)(H,123,145)(H,124,140)(H,125,134)(H,148,149)/t54-,55+,72-,73-,74-,75-,76-,77-,78+,79+,80-,81-,82-,83+,89+/m0/s1	VWFLFTLWXQPVNV-SYUZYMOHSA-N	50286613	CHEMBL413825::Cyclic (Gly1-Asp9) (Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp)	Endothelin-1 receptor			>5000							ChEMBL	10.1016/0960-894X(95)00084-7	10.7270/Q27081DM				He, JX; Cody, WL; Flynn, MA; Welch, KM; Reynolds, EE; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50286613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50286613&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			91934863	104128184		CHEMBL413825					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006313	CCCOc1ccc2n(Cc3ccc4OCOc4c3)c(C(O)=O)c(-c3ccc4OCOc4c3)c2c1	InChI=1S/C27H23NO7/c1-2-9-31-18-5-6-20-19(12-18)25(17-4-8-22-24(11-17)35-15-33-22)26(27(29)30)28(20)13-16-3-7-21-23(10-16)34-14-32-21/h3-8,10-12H,2,9,13-15H2,1H3,(H,29,30)	LQWGCVIETCFLOP-UHFFFAOYSA-N	50069567	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-5-propoxy-1H-indole-2-carboxylic acid::CHEMBL10218	Endothelin-1 receptor			 130							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069567&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44266552	103963627		CHEMBL10218				ZINC26005428	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006315	CC(C)Oc1c(sc2ccc(OCc3ccccc3)cc12)C(O)=O	InChI=1S/C19H18O4S/c1-12(2)23-17-15-10-14(22-11-13-6-4-3-5-7-13)8-9-16(15)24-18(17)19(20)21/h3-10,12H,11H2,1-2H3,(H,20,21)	MFIHFDWJBWXRFD-UHFFFAOYSA-N	50287187	5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid::CHEMBL10143	Endothelin-1 receptor			 8800							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			14673588	104128758		CHEMBL10143				ZINC26004833	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50006316	CCCOc1ccc2c(c(C(O)=O)n(Cc3ccc4OCOc4c3)c2c1)-c1ccc2OCOc2c1	InChI=1S/C27H23NO7/c1-2-9-31-18-5-6-19-20(12-18)28(13-16-3-7-21-23(10-16)34-14-32-21)26(27(29)30)25(19)17-4-8-22-24(11-17)35-15-33-22/h3-8,10-12H,2,9,13-15H2,1H3,(H,29,30)	OYUYFTQOLVQNJA-UHFFFAOYSA-N	50289234	3-Benzo[1,3]dioxol-5-yl-1-benzo[1,3]dioxol-5-ylmethyl-6-propoxy-1H-indole-2-carboxylic acid::CHEMBL268751	Endothelin-1 receptor			 47							ChEMBL	10.1016/0960-894X(96)00170-9	10.7270/Q2ZK5GNC				Bunker, AM; Edmunds, JJ; Berryman, KA; Walker, DM; Flynn, MA; Welch, KM; Doherty, AM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289234&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9869444	104130805		CHEMBL268751				ZINC01544312	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50002126	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C44H61N7O10/c1-8-25(5)37(42(58)49-35(44(60)61)21-29-23-45-31-18-14-13-17-30(29)31)51-43(59)38(26(6)9-2)50-41(57)34(22-36(53)54)48-39(55)32(19-24(3)4)47-40(56)33(46-27(7)52)20-28-15-11-10-12-16-28/h10-18,23-26,32-35,37-38,45H,8-9,19-22H2,1-7H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t25-,26-,32-,33+,34-,35-,37-,38-/m0/s1	DHRNHNAPGPSYGB-YNIJNJSISA-N	50001217	3-[2-(2-Acetylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-N-(1-{1-[1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL86814	Endothelin-1 receptor			 2800							ChEMBL	10.1016/S0960-894X(01)81215-4	10.7270/Q2M908MP				Doherty, AM; Cody, WL; He, JX; DePue, PL; Leonard, DM; Jr., JD; Hill, KE; Flynn, MA; Reynolds, EE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001217&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			15297023	103915682		CHEMBL86814				ZINC95610946	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50559546	CC[C@@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCN)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C43H60N8O10/c1-6-24(3)36(41(58)49-34(43(60)61)21-28-23-45-30-17-12-11-16-29(28)30)51-42(59)37(25(4)7-2)50-40(57)33(22-35(53)54)48-38(55)31(18-13-19-44)47-39(56)32(46-26(5)52)20-27-14-9-8-10-15-27/h8-12,14-17,23-25,31-34,36-37,45H,6-7,13,18-22,44H2,1-5H3,(H,46,52)(H,47,56)(H,48,55)(H,49,58)(H,50,57)(H,51,59)(H,53,54)(H,60,61)/t24-,25-,31+,32-,33+,34+,36+,37+/m1/s1	WXVKATPLQWNUHO-PLXHBALWSA-N	50281584	(S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-5-amino-pentanoylamino]-N-((1S,2R)-1-{(1S,2R)-1-[(S)-1-carboxy-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butylcarbamoyl}-2-methyl-butyl)-succinamic acid::CHEMBL423941	Endothelin-1 receptor			<800							ChEMBL	10.1016/S0960-894X(01)81219-1	10.7270/Q27081C5				Spellmeyer, DC; Brown, S; Stauber, GB; Geysen, H; Valerio, R	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281584&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44365953	104123258		CHEMBL423941				ZINC95614282	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50547442	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@H]2CSSC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC2=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C109H159N25O32S5/c1-12-56(9)87(107(163)125-76(109(165)166)39-60-43-113-65-24-18-17-23-63(60)65)134-108(164)88(57(10)13-2)133-99(155)75(42-85(143)144)123-94(150)70(36-54(5)6)118-97(153)73(40-61-44-112-52-114-61)121-103(159)80-49-169-168-48-64(111)89(145)126-77(45-135)102(158)131-81-50-170-171-51-82(105(161)132-86(55(7)8)106(162)124-72(38-59-26-28-62(138)29-27-59)95(151)120-71(96(152)130-80)37-58-21-15-14-16-22-58)129-91(147)67(30-31-83(139)140)116-90(146)66(25-19-20-33-110)115-98(154)74(41-84(141)142)122-92(148)68(32-34-167-11)117-93(149)69(35-53(3)4)119-100(156)78(46-136)127-101(157)79(47-137)128-104(81)160/h14-18,21-24,26-29,43-44,52-57,64,66-82,86-88,113,135-138H,12-13,19-20,25,30-42,45-51,110-111H2,1-11H3,(H,112,114)(H,115,154)(H,116,146)(H,117,149)(H,118,153)(H,119,156)(H,120,151)(H,121,159)(H,122,148)(H,123,150)(H,124,162)(H,125,163)(H,126,145)(H,127,157)(H,128,160)(H,129,147)(H,130,152)(H,131,158)(H,132,161)(H,133,155)(H,134,164)(H,139,140)(H,141,142)(H,143,144)(H,165,166)/t56-,57-,64-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,86-,87-,88-/m0/s1	ZUBDGKVDJUIMQQ-ZTNLKOGPSA-N	50155246	CHEMBL3775234	Endothelin-1 receptor			 0.023							ChEMBL	10.1016/j.bmc.2016.11.014	10.7270/Q2CF9S3S	27876250			Gunia-Krzyzak, A; Zelaszczyk, D; Rapacz, A; Zeslawska, E; Waszkielewicz, AM; Panczyk, K; Sloczynska, K; Pekala, E; Nitek, W; Filipek, B; Marona, H	Jagiellonian University Medical College	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155246&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16212950	340133542		CHEMBL3775234					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50671374	CC[C@H](C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O	InChI=1S/C47H59N7O10/c1-6-27(3)40(45(61)52-38(47(63)64)24-32-26-48-34-21-15-14-20-33(32)34)54-46(62)41(28(4)7-2)53-44(60)37(25-39(56)57)51-43(59)36(23-31-18-12-9-13-19-31)50-42(58)35(49-29(5)55)22-30-16-10-8-11-17-30/h8-21,26-28,35-38,40-41,48H,6-7,22-25H2,1-5H3,(H,49,55)(H,50,58)(H,51,59)(H,52,61)(H,53,60)(H,54,62)(H,56,57)(H,63,64)/t27-,28-,35+,36-,37-,38-,40-,41-/m0/s1	GNRBLKLDFZWDTC-ALDIRDDTSA-N	50045244	(S)-3-[(S)-2-((R)-2-Acetylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-N-{(S)-1-[(S)-(S)-1-((S)-1-carboxy-2-(S)-1H-indol-3-yl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-2-methyl-butyl}-succinamic acid::Ac-D-Phe-D-Phe-Asp-Ile-Ile-Trp::CHEMBL313984	Endothelin-1 receptor			 200							ChEMBL	10.1021/jm00070a001	10.7270/Q2V69K6K	8410970			Doherty, AM; Cody, WL; DePue, PL; He, JX; Waite, LA; Leonard, DM; Leitz, NL; Dudley, DT; Rapundalo, ST; Hingorani, GP	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045244&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44321226	103976335		CHEMBL313984					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780321	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC=C)ccc12	InChI=1S/C31H27NO8/c1-3-10-38-22-8-9-25-23(15-22)29(33)24(12-18-6-5-7-20(11-18)30(34)35)28(31(36)37)32(25)16-21-14-27-26(39-17-40-27)13-19(21)4-2/h3,5-9,11,13-15H,1,4,10,12,16-17H2,2H3,(H,34,35)(H,36,37)	YPYVZNCHGXISOT-UHFFFAOYSA-N	50329841	6-(Allyloxy)-3-(3-carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271479	Endothelin-1 receptor			 38							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329841&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630532	123108956		CHEMBL1271479				ZINC64513143	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780323	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(O)ccc12	InChI=1S/C28H23NO8/c1-2-16-10-23-24(37-14-36-23)11-18(16)13-29-22-7-6-19(30)12-20(22)26(31)21(25(29)28(34)35)9-15-4-3-5-17(8-15)27(32)33/h3-8,10-12,30H,2,9,13-14H2,1H3,(H,32,33)(H,34,35)	FFJSPULNDJGPKT-UHFFFAOYSA-N	50329837	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-hydroxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272137	Endothelin-1 receptor			 37							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329837&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			24997097	123108952		CHEMBL1272137				ZINC64527159	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780325	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCOC)ccc12	InChI=1S/C30H27NO9/c1-3-18-11-25-26(40-16-39-25)12-20(18)14-31-24-8-7-21(38-15-37-2)13-22(24)28(32)23(27(31)30(35)36)10-17-5-4-6-19(9-17)29(33)34/h4-9,11-13H,3,10,14-16H2,1-2H3,(H,33,34)(H,35,36)	GNUKWUWFLYQCGT-UHFFFAOYSA-N	50329842	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-(methoxymethoxy)-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271531	Endothelin-1 receptor			 24							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329842&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630654	123108957		CHEMBL1271531				ZINC64513681	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780326	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCOC)ccc12	InChI=1S/C30H27N5O7/c1-3-18-11-25-26(42-16-41-25)12-20(18)14-35-24-8-7-21(40-15-39-2)13-22(24)28(36)23(27(35)30(37)38)10-17-5-4-6-19(9-17)29-31-33-34-32-29/h4-9,11-13H,3,10,14-16H2,1-2H3,(H,37,38)(H,31,32,33,34)	PBTTZSSLQDEUPI-UHFFFAOYSA-N	50249529	CHEMBL4067475	Endothelin-1 receptor			 17							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249529&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137633242	401961627							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780327	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC(C)C)ccc12	InChI=1S/C32H31NO8/c1-4-20-12-27-28(41-17-40-27)13-22(20)15-33-26-9-8-23(39-16-18(2)3)14-24(26)30(34)25(29(33)32(37)38)11-19-6-5-7-21(10-19)31(35)36/h5-10,12-14,18H,4,11,15-17H2,1-3H3,(H,35,36)(H,37,38)	ASYDIUHFIWWNJR-UHFFFAOYSA-N	50329844	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-6-isobutoxy-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271640	Endothelin-1 receptor			 9.9							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329844&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52949155	123108959		CHEMBL1271640				ZINC64513129	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780333	CCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)-c3nnn[nH]3)c(=O)c2c1	InChI=1S/C30H27N5O6/c1-3-18-12-25-26(41-16-40-25)13-20(18)15-35-24-9-8-21(39-4-2)14-22(24)28(36)23(27(35)30(37)38)11-17-6-5-7-19(10-17)29-31-33-34-32-29/h5-10,12-14H,3-4,11,15-16H2,1-2H3,(H,37,38)(H,31,32,33,34)	OWXIHVSRTAHZLT-UHFFFAOYSA-N	50249530	CHEMBL4088349	Endothelin-1 receptor			 7.1							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249530&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137642741	401961628							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780335	CCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C30H27NO8/c1-3-18-12-25-26(39-16-38-25)13-20(18)15-31-24-9-8-21(37-4-2)14-22(24)28(32)23(27(31)30(35)36)11-17-6-5-7-19(10-17)29(33)34/h5-10,12-14H,3-4,11,15-16H2,1-2H3,(H,33,34)(H,35,36)	UWVSLXNFMJFARF-UHFFFAOYSA-N	50329838	3-(3-Carboxybenzyl)-6-ethoxy-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272190	Endothelin-1 receptor			 6.6							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329838&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52943105	123108953		CHEMBL1272190				ZINC64526379	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780336	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCC(C)C)ccc12	InChI=1S/C32H31N5O6/c1-4-20-12-27-28(43-17-42-27)13-22(20)15-37-26-9-8-23(41-16-18(2)3)14-24(26)30(38)25(29(37)32(39)40)11-19-6-5-7-21(10-19)31-33-35-36-34-31/h5-10,12-14,18H,4,11,15-17H2,1-3H3,(H,39,40)(H,33,34,35,36)	UZLLGNWABVRSKB-UHFFFAOYSA-N	50249531	CHEMBL4081426	Endothelin-1 receptor			 6.2							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249531&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137647152	401961629							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780338	CCCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C32H31NO8/c1-3-5-11-39-23-9-10-26-24(16-23)30(34)25(13-19-7-6-8-21(12-19)31(35)36)29(32(37)38)33(26)17-22-15-28-27(40-18-41-28)14-20(22)4-2/h6-10,12,14-16H,3-5,11,13,17-18H2,1-2H3,(H,35,36)(H,37,38)	KAAWXPGZQHJMQL-UHFFFAOYSA-N	50329843	6-Butoxy-3-(3-carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271586	Endothelin-1 receptor			 1.9							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329843&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			42630655	123108958		CHEMBL1271586				ZINC64512459	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780339	CCCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)-c3nnn[nH]3)c(=O)c2c1	InChI=1S/C32H31N5O6/c1-3-5-11-41-23-9-10-26-24(16-23)30(38)25(13-19-7-6-8-21(12-19)31-33-35-36-34-31)29(32(39)40)37(26)17-22-15-28-27(42-18-43-28)14-20(22)4-2/h6-10,12,14-16H,3-5,11,13,17-18H2,1-2H3,(H,39,40)(H,33,34,35,36)	SCOBRKBPUKEATJ-UHFFFAOYSA-N	50249532	CHEMBL4061110	Endothelin-1 receptor			 1.2							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249532&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137637038	401961630							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780340	CCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)-c3nnn[nH]3)c(=O)c2c1	InChI=1S/C31H29N5O6/c1-3-10-40-22-8-9-25-23(15-22)29(37)24(12-18-6-5-7-20(11-18)30-32-34-35-33-30)28(31(38)39)36(25)16-21-14-27-26(41-17-42-27)13-19(21)4-2/h5-9,11,13-15H,3-4,10,12,16-17H2,1-2H3,(H,38,39)(H,32,33,34,35)	MODHKIOUVGRQCC-UHFFFAOYSA-N	50249533	CHEMBL4078537	Endothelin-1 receptor			 0.800000							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249533&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137649592	401961631							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780341	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCC3CCC3)ccc12	InChI=1S/C33H31N5O6/c1-2-21-13-28-29(44-18-43-28)14-23(21)16-38-27-10-9-24(42-17-19-5-3-6-19)15-25(27)31(39)26(30(38)33(40)41)12-20-7-4-8-22(11-20)32-34-36-37-35-32/h4,7-11,13-15,19H,2-3,5-6,12,16-18H2,1H3,(H,40,41)(H,34,35,36,37)	VQKDQUCIEIPABF-UHFFFAOYSA-N	50249534	CHEMBL4068786	Endothelin-1 receptor			 279							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249534&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137633653	401961632							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780342	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCCN)ccc12	InChI=1S/C30H28N6O6/c1-2-18-12-25-26(42-16-41-25)13-20(18)15-36-24-7-6-21(40-9-8-31)14-22(24)28(37)23(27(36)30(38)39)11-17-4-3-5-19(10-17)29-32-34-35-33-29/h3-7,10,12-14H,2,8-9,11,15-16,31H2,1H3,(H,38,39)(H,32,33,34,35)	DKRMKDLKTIKQIE-UHFFFAOYSA-N	50249535	CHEMBL4096211	Endothelin-1 receptor			 373							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249535&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137655285	401961633							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780345	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCCN)ccc12	InChI=1S/C30H28N2O8/c1-2-18-12-25-26(40-16-39-25)13-20(18)15-32-24-7-6-21(38-9-8-31)14-22(24)28(33)23(27(32)30(36)37)11-17-4-3-5-19(10-17)29(34)35/h3-7,10,12-14H,2,8-9,11,15-16,31H2,1H3,(H,34,35)(H,36,37)	KOOUDZAGMGUBEY-UHFFFAOYSA-N	50249536	CHEMBL4076290	Endothelin-1 receptor			 365							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249536&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137652304	401961634							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780347	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCC3CC3)ccc12	InChI=1S/C32H29N5O6/c1-2-20-12-27-28(43-17-42-27)13-22(20)15-37-26-9-8-23(41-16-18-6-7-18)14-24(26)30(38)25(29(37)32(39)40)11-19-4-3-5-21(10-19)31-33-35-36-34-31/h3-5,8-10,12-14,18H,2,6-7,11,15-17H2,1H3,(H,39,40)(H,33,34,35,36)	NHKDLOQLHLFRRT-UHFFFAOYSA-N	50249537	CHEMBL4071505	Endothelin-1 receptor			 78							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249537&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137638953	401961635							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780365	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCC3CCCC3)ccc12	InChI=1S/C34H33N5O6/c1-2-22-14-29-30(45-19-44-29)15-24(22)17-39-28-11-10-25(43-18-20-6-3-4-7-20)16-26(28)32(40)27(31(39)34(41)42)13-21-8-5-9-23(12-21)33-35-37-38-36-33/h5,8-12,14-16,20H,2-4,6-7,13,17-19H2,1H3,(H,41,42)(H,35,36,37,38)	GLACAXDCNXOWGM-UHFFFAOYSA-N	50249538	CHEMBL4072165	Endothelin-1 receptor			 873							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249538&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137639474	401961636							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780370	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC3CCCC3)ccc12	InChI=1S/C34H33NO8/c1-2-22-14-29-30(43-19-42-29)15-24(22)17-35-28-11-10-25(41-18-20-6-3-4-7-20)16-26(28)32(36)27(31(35)34(39)40)13-21-8-5-9-23(12-21)33(37)38/h5,8-12,14-16,20H,2-4,6-7,13,17-19H2,1H3,(H,37,38)(H,39,40)	WXLDFOOIWYKOLI-UHFFFAOYSA-N	50249507	CHEMBL4078297	Endothelin-1 receptor			 1024							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249507&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137649809	401961626							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780378	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22-,23+,24-,26+/m0/s1	VYCMAAOURFJIHD-TYUWDEHNSA-N	50249564	CHEMBL4095638	Endothelin-1 receptor			 7.3							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249564&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			101039204	401961639							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780379	CCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C31H29NO8/c1-3-10-38-22-8-9-25-23(15-22)29(33)24(12-18-6-5-7-20(11-18)30(34)35)28(31(36)37)32(25)16-21-14-27-26(39-17-40-27)13-19(21)4-2/h5-9,11,13-15H,3-4,10,12,16-17H2,1-2H3,(H,34,35)(H,36,37)	JZVDVZMUHGSKGI-UHFFFAOYSA-N	50329839	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-6-propoxy-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272244	Endothelin-1 receptor			 4.2							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329839&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			25211074	123108954		CHEMBL1272244				ZINC59096876	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780380	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(OCC=C)ccc12	InChI=1S/C31H27N5O6/c1-3-10-40-22-8-9-25-23(15-22)29(37)24(12-18-6-5-7-20(11-18)30-32-34-35-33-30)28(31(38)39)36(25)16-21-14-27-26(41-17-42-27)13-19(21)4-2/h3,5-9,11,13-15H,1,4,10,12,16-17H2,2H3,(H,38,39)(H,32,33,34,35)	RGQAYSMKTZIBMN-UHFFFAOYSA-N	50249563	CHEMBL4100579	Endothelin-1 receptor			 48							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249563&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137661460	401961638							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780383	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)-c2nnn[nH]2)c(=O)c2cc(O)ccc12	InChI=1S/C28H23N5O6/c1-2-16-10-23-24(39-14-38-23)11-18(16)13-33-22-7-6-19(34)12-20(22)26(35)21(25(33)28(36)37)9-15-4-3-5-17(8-15)27-29-31-32-30-27/h3-8,10-12,34H,2,9,13-14H2,1H3,(H,36,37)(H,29,30,31,32)	GWJFUFDQTPBTHW-UHFFFAOYSA-N	50249521	CHEMBL4096346	Endothelin-1 receptor			 29							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249521&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137655525	104103798						ZINC31623388	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780387	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC3CC3)ccc12	InChI=1S/C32H29NO8/c1-2-20-12-27-28(41-17-40-27)13-22(20)15-33-26-9-8-23(39-16-18-6-7-18)14-24(26)30(34)25(29(33)32(37)38)11-19-4-3-5-21(10-19)31(35)36/h3-5,8-10,12-14,18H,2,6-7,11,15-17H2,1H3,(H,35,36)(H,37,38)	HXUVUUFEMYJLDB-UHFFFAOYSA-N	50329846	3-(3-Carboxybenzyl)-6-(cyclopropylmethoxy)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1271746	Endothelin-1 receptor			 121							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329846&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			52949197	123108961		CHEMBL1271746				ZINC64539279	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780388	CCc1cc2OCOc2cc1Cn1c(C(O)=O)c(Cc2cccc(c2)C(O)=O)c(=O)c2cc(OCC3CCC3)ccc12	InChI=1S/C33H31NO8/c1-2-21-13-28-29(42-18-41-28)14-23(21)16-34-27-10-9-24(40-17-19-5-3-6-19)15-25(27)31(35)26(30(34)33(38)39)12-20-7-4-8-22(11-20)32(36)37/h4,7-11,13-15,19H,2-3,5-6,12,16-18H2,1H3,(H,36,37)(H,38,39)	LQXABJNKFHBROP-UHFFFAOYSA-N	50249558	CHEMBL4088634	Endothelin-1 receptor			 342							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50249558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50249558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			137643691	401961637							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50916483	CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)N[C@H]2C[C@@H](C2)C(O)=O)c2ccccc12	InChI=1S/C30H37N3O5S2/c1-30(2,3)33-40(37,38)25-14-13-23(21-11-7-8-12-22(21)25)26-24(15-18-9-5-4-6-10-18)32-28(39-26)27(34)31-20-16-19(17-20)29(35)36/h7-8,11-14,18-20,33H,4-6,9-10,15-17H2,1-3H3,(H,31,34)(H,35,36)/t19-,20-	KYIGOCCCBXRHNJ-MXVIHJGJSA-N	392076	US10301272, Example 7/9	Endothelin-1 receptor			 0.023000							ChEMBL	10.1016/j.bmcl.2018.03.093	10.7270/Q27W6FPC	29631962			Gege, C; Cummings, MD; Albers, M; Kinzel, O; Kleymann, G; Schlüter, T; Steeneck, C; Nelen, MI; Milligan, C; Spurlino, J; Xue, X; Leonard, K; Edwards, JP; Fourie, A; Goldberg, SD; Hoffmann, T	Phenex Pharmaceuticals AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=392076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=392076&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			72548703	404960416							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
50780314	CCCOc1ccc2n(Cc3cc4OCOc4cc3CC)c(C(O)=O)c(Cc3cccc(c3)C(O)=O)c(=O)c2c1	InChI=1S/C31H29NO8/c1-3-10-38-22-8-9-25-23(15-22)29(33)24(12-18-6-5-7-20(11-18)30(34)35)28(31(36)37)32(25)16-21-14-27-26(39-17-40-27)13-19(21)4-2/h5-9,11,13-15H,3-4,10,12,16-17H2,1-2H3,(H,34,35)(H,36,37)	JZVDVZMUHGSKGI-UHFFFAOYSA-N	50329839	3-(3-Carboxybenzyl)-1-[(6-ethylbenzo[d][1,3]dioxol-5-yl)methyl]-4-oxo-6-propoxy-1,4-dihydroquinoline-2-carboxylic acid::CHEMBL1272244	Endothelin-1 receptor			 4							ChEMBL	10.1016/j.bmcl.2017.04.049	10.7270/Q2Q52S21	28462837			Khadtare, N; Stephani, R; Korlipara, V	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329839&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			25211074	123108954		CHEMBL1272244				ZINC59096876	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184851	CCOC(=O)c1ccc2c(cn(C)c2c1)C(C(=O)NS(=O)(=O)c1ccc(C)cc1OC)c1ccc2OCOc2c1	InChI=1S/C29H28N2O8S/c1-5-37-29(33)19-7-9-20-21(15-31(3)22(20)13-19)27(18-8-10-23-24(14-18)39-16-38-23)28(32)30-40(34,35)26-11-6-17(2)12-25(26)36-4/h6-15,27H,5,16H2,1-4H3,(H,30,32)	WUYGPPAFDHJCRQ-UHFFFAOYSA-N	50487273	CHEMBL2261602	Endothelin-1 receptor			 18							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487273&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			76319370	433954538							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184852	COCc1ccc2c(cn(C)c2c1)C(C(=O)NS(=O)(=O)c1ccc(C)cc1OC)c1ccc2OCOc2c1	InChI=1S/C28H28N2O7S/c1-17-5-10-26(25(11-17)35-4)38(32,33)29-28(31)27(19-7-9-23-24(13-19)37-16-36-23)21-14-30(2)22-12-18(15-34-3)6-8-20(21)22/h5-14,27H,15-16H2,1-4H3,(H,29,31)	PKHUJBTZRIYKHG-UHFFFAOYSA-N	50487274	CHEMBL2261601	Endothelin-1 receptor			 8.8							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487274&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467230	433954539							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184853	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(Cl)ccc12)c1ccc2OCOc2c1	InChI=1S/C26H23ClN2O6S/c1-15-4-9-24(23(10-15)33-3)36(31,32)28-26(30)25(16-5-8-21-22(11-16)35-14-34-21)19-13-29(2)20-12-17(27)6-7-18(19)20/h4-13,25H,14H2,1-3H3,(H,28,30)	FDVBFLHJYUCEKU-UHFFFAOYSA-N	50487272	CHEMBL2261363	Endothelin-1 receptor			 46							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487272&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			76330201	433954537							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184854	Cc1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(CO)ccc12)c1ccc2OCOc2c1	InChI=1S/C26H24N2O6S/c1-16-3-7-19(8-4-16)35(31,32)27-26(30)25(18-6-10-23-24(12-18)34-15-33-23)21-13-28(2)22-11-17(14-29)5-9-20(21)22/h3-13,25,29H,14-15H2,1-2H3,(H,27,30)	ZJAICLYAYAWLME-UHFFFAOYSA-N	50487281	CHEMBL2261362	Endothelin-1 receptor			 34							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487281&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467219	433954546							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184855	COc1cc(C)ccc1S(=O)(=O)NC(=O)[C@H](c1cn(C)c2cc(CO)ccc12)c1ccc2OCOc2c1	InChI=1S/C27H26N2O7S/c1-16-4-9-25(24(10-16)34-3)37(32,33)28-27(31)26(18-6-8-22-23(12-18)36-15-35-22)20-13-29(2)21-11-17(14-30)5-7-19(20)21/h4-13,26,30H,14-15H2,1-3H3,(H,28,31)/t26-/m0/s1	PGAMLYVKCIXYNX-SANMLTNESA-N	50487277	CHEMBL2261361	Endothelin-1 receptor			 2.2							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487277&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			76312118	433954542							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184856	COc1cc(C)ccc1S(=O)(=O)NC(=O)[C@H](c1cn(C)c2cc(ccc12)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H24N2O8S/c1-15-4-9-24(23(10-15)35-3)38(33,34)28-26(30)25(16-6-8-21-22(12-16)37-14-36-21)19-13-29(2)20-11-17(27(31)32)5-7-18(19)20/h4-13,25H,14H2,1-3H3,(H,28,30)(H,31,32)/t25-/m0/s1	RXNZJEAMURXNLG-VWLOTQADSA-N	50487278	CHEMBL2261359	Endothelin-1 receptor		 4.2								ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487278&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9807200	433954543							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184857	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H24N2O8S/c1-15-4-9-24(23(10-15)35-3)38(33,34)28-26(30)25(16-6-8-21-22(12-16)37-14-36-21)19-13-29(2)20-11-17(27(31)32)5-7-18(19)20/h4-13,25H,14H2,1-3H3,(H,28,30)(H,31,32)	RXNZJEAMURXNLG-UHFFFAOYSA-N	50487279	CHEMBL2261358	Endothelin-1 receptor			 5.3							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487279&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22009947	433954544							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184858	Cn1cc(C(C(=O)NS(=O)(=O)c2ccc(CC(O)=O)cc2)c2ccc3OCOc3c2)c2ccc(cc12)C(N)=O	InChI=1S/C27H23N3O8S/c1-30-13-20(19-8-4-17(26(28)33)11-21(19)30)25(16-5-9-22-23(12-16)38-14-37-22)27(34)29-39(35,36)18-6-2-15(3-7-18)10-24(31)32/h2-9,11-13,25H,10,14H2,1H3,(H2,28,33)(H,29,34)(H,31,32)	IDINHRPVYGDPHV-UHFFFAOYSA-N	50487280	CHEMBL2261357	Endothelin-1 receptor			 1.7							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487280&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467237	433954545					C03768		1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184859	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccccc12	InChI=1S/C28H28N2O5S/c1-4-30-16-23(22-7-5-6-8-24(22)30)27(20-11-14-25-26(15-20)35-17-34-25)28(31)29-36(32,33)21-12-9-19(10-13-21)18(2)3/h5-16,18,27H,4,17H2,1-3H3,(H,29,31)	IRSFNAANHUHAKL-UHFFFAOYSA-N	50487282	CHEMBL2261356	Endothelin-1 receptor			 560							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487282&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			76326542	433954547							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184860	CCOc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C28H27N3O7S/c1-4-36-24-11-16(2)5-10-25(24)39(34,35)30-28(33)26(17-7-9-22-23(13-17)38-15-37-22)20-14-31(3)21-12-18(27(29)32)6-8-19(20)21/h5-14,26H,4,15H2,1-3H3,(H2,29,32)(H,30,33)	UEHPBBFVUYURNP-UHFFFAOYSA-N	50108204	3-[1-Benzo[1,3]dioxol-5-yl-2-(2-ethoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22513	Endothelin-1 receptor			 0.550000							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108204&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9915510	104003425		CHEMBL22513				ZINC14141063	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184865	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(F)ccc12)c1ccc2OCOc2c1	InChI=1S/C26H23FN2O6S/c1-15-4-9-24(23(10-15)33-3)36(31,32)28-26(30)25(16-5-8-21-22(11-16)35-14-34-21)19-13-29(2)20-12-17(27)6-7-18(19)20/h4-13,25H,14H2,1-3H3,(H,28,30)	ZLSUWQHIYSFEQP-UHFFFAOYSA-N	50487276	CHEMBL2261364	Endothelin-1 receptor			 14							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487276&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44214320	433954541							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184866	COc1cc(C)ccc1S(=O)(=O)NC(=O)[C@H](c1cn(C)c2cc(CO)ccc12)c1ccc2OCOc2c1	InChI=1S/C27H26N2O7S/c1-16-4-9-25(24(10-16)34-3)37(32,33)28-27(31)26(18-6-8-22-23(12-18)36-15-35-22)20-13-29(2)21-11-17(14-30)5-7-19(20)21/h4-13,26,30H,14-15H2,1-3H3,(H,28,31)/t26-/m0/s1	PGAMLYVKCIXYNX-SANMLTNESA-N	50487277	CHEMBL2261361	Endothelin-1 receptor		 2.2								ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487277&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			76312118	433954542							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184867	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C27H25N3O7S/c1-15-4-9-24(23(10-15)35-3)38(33,34)29-27(32)25(16-6-8-21-22(12-16)37-14-36-21)19-13-30(2)20-11-17(26(28)31)5-7-18(19)20/h4-13,25H,14H2,1-3H3,(H2,28,31)(H,29,32)	XSSAXXJNGRXQCR-UHFFFAOYSA-N	50108192	3-[1-Benzo[1,3]dioxol-5-yl-2-(2-methoxy-4-methyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL22562	Endothelin-1 receptor			 1.1							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108192&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10347080	104003413		CHEMBL22562				ZINC28258137	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184868	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(N)=O)c1ccc2OCOc2c1	InChI=1S/C28H27N3O6S/c1-16(2)17-4-8-20(9-5-17)38(34,35)30-28(33)26(18-7-11-24-25(13-18)37-15-36-24)22-14-31(3)23-12-19(27(29)32)6-10-21(22)23/h4-14,16,26H,15H2,1-3H3,(H2,29,32)(H,30,33)	MWZFOVILFVOLMJ-UHFFFAOYSA-N	50108187	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid::3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-methyl-1H-indole-6-carboxylic acid amide::CHEMBL262784	Endothelin-1 receptor			 2.3							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108187&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467235	104003408		CHEMBL262784				ZINC28257415	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184869	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(CO)ccc12)c1ccc2OCOc2c1	InChI=1S/C27H26N2O7S/c1-16-4-9-25(24(10-16)34-3)37(32,33)28-27(31)26(18-6-8-22-23(12-18)36-15-35-22)20-13-29(2)21-11-17(14-30)5-7-19(20)21/h4-13,26,30H,14-15H2,1-3H3,(H,28,31)	PGAMLYVKCIXYNX-UHFFFAOYSA-N	50487284	CHEMBL2261360	Endothelin-1 receptor			 8.7							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487284&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467266	433954549							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184871	COc1cc(C)ccc1S(=O)(=O)NC(=O)[C@H](c1cn(C)c2cc(ccc12)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C27H24N2O8S/c1-15-4-9-24(23(10-15)35-3)38(33,34)28-26(30)25(16-6-8-21-22(12-16)37-14-36-21)19-13-29(2)20-11-17(27(31)32)5-7-18(19)20/h4-13,25H,14H2,1-3H3,(H,28,30)(H,31,32)/t25-/m0/s1	RXNZJEAMURXNLG-VWLOTQADSA-N	50487278	CHEMBL2261359	Endothelin-1 receptor			 4.2							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487278&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9807200	433954543							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184873	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C(C)=O)c1ccc2OCOc2c1	InChI=1S/C28H26N2O7S/c1-16-5-10-26(25(11-16)35-4)38(33,34)29-28(32)27(19-7-9-23-24(13-19)37-15-36-23)21-14-30(3)22-12-18(17(2)31)6-8-20(21)22/h5-14,27H,15H2,1-4H3,(H,29,32)	ZXSBLFBQTHAAHA-UHFFFAOYSA-N	50487283	CHEMBL2261599	Endothelin-1 receptor			 1.4							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487283&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			22467234	433954548							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184874	COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1cn(C)c2cc(ccc12)C#N)c1ccc2OCOc2c1	InChI=1S/C27H23N3O6S/c1-16-4-9-25(24(10-16)34-3)37(32,33)29-27(31)26(18-6-8-22-23(12-18)36-15-35-22)20-14-30(2)21-11-17(13-28)5-7-19(20)21/h4-12,14,26H,15H2,1-3H3,(H,29,31)	VACPWIZSMORWDJ-UHFFFAOYSA-N	50487275	CHEMBL2261600	Endothelin-1 receptor			 11							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487275&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			76308472	433954540							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51184875	CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(cc2)C(C)C)c2ccc3OCOc3c2)c2ccc(cc12)C(O)=O	InChI=1S/C29H28N2O7S/c1-4-31-15-23(22-11-7-20(29(33)34)13-24(22)31)27(19-8-12-25-26(14-19)38-16-37-25)28(32)30-39(35,36)21-9-5-18(6-10-21)17(2)3/h5-15,17,27H,4,16H2,1-3H3,(H,30,32)(H,33,34)	GBDHMDQPXDYBRO-UHFFFAOYSA-N	50108207	3-[1-Benzo[1,3]dioxol-5-yl-2-(4-isopropyl-benzenesulfonylamino)-2-oxo-ethyl]-1-ethyl-1H-indole-6-carboxylic acid::CHEMBL23833	Endothelin-1 receptor			 32							ChEMBL	10.1007/s00044-004-0021-y	10.7270/Q2K64N0B				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108207&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18738879	104003428		CHEMBL23833				ZINC28261367	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51189822	CC(C)C[C@@H]1NC(=O)[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(C)C	InChI=1S/C31H42N6O7/c1-16(2)12-21-27(40)33-22(13-18-15-32-20-9-6-5-8-19(18)20)28(41)35-23(14-25(38)39)31(44)37-11-7-10-24(37)29(42)36-26(17(3)4)30(43)34-21/h5-6,8-9,15-17,21-24,26,32H,7,10-14H2,1-4H3,(H,33,40)(H,34,43)(H,35,41)(H,36,42)(H,38,39)/t21-,22+,23+,24-,26+/m0/s1	VYCMAAOURFJIHD-PJNXIOHISA-N	50197954	CHEBI:2965::CHEMBL314691	Endothelin-1 receptor			 37							ChEMBL	10.1007/s00044-013-0542-3	10.7270/Q27084BZ				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197954&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			443289	375978092		CHEMBL314691			C11587		1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51189827	Cc1c(oc2cccc(OCc3ccccc3)c12)C(O)=O	InChI=1S/C17H14O4/c1-11-15-13(20-10-12-6-3-2-4-7-12)8-5-9-14(15)21-16(11)17(18)19/h2-9H,10H2,1H3,(H,18,19)	KNEMRZPIQXICQF-UHFFFAOYSA-N	50489116	CHEMBL2296889	Endothelin-1 receptor			 3800							ChEMBL	10.1007/s00044-013-0542-3	10.7270/Q27084BZ				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50489116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50489116&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10540843	433956381							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51189828	COc1cccc2oc(C(O)=O)c(C)c12	InChI=1S/C11H10O4/c1-6-9-7(14-2)4-3-5-8(9)15-10(6)11(12)13/h3-5H,1-2H3,(H,12,13)	MBJKFAUPYMUFOV-UHFFFAOYSA-N	50489117	CHEMBL2296888	Endothelin-1 receptor			 11000							ChEMBL	10.1007/s00044-013-0542-3	10.7270/Q27084BZ				n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50489117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50489117&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			13044638	433956382							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51214982	CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	KVVLFJLSBAOKPZ-UHFFFAOYSA-N	50499311	CHEMBL3736156	Endothelin-1 receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499311&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034967	433911212							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51214995	CB1Nc2c(OCC(O)CN(C)C)cccc2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-11-5-4-6-13(14(11)16-15)19-10-12(18)9-17(2)3/h4-8,12,16,18H,9-10H2,1-3H3	CCSPGLLRANVKRG-UHFFFAOYSA-N	50499310	CHEMBL3736433	Endothelin-1 receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499310&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034966	433911211							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51215033	CB1Nc2c(OCC(O)CN(C)C)cccc2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-11-5-4-6-13(14(11)16-15)19-10-12(18)9-17(2)3/h4-8,12,16,18H,9-10H2,1-3H3	CCSPGLLRANVKRG-UHFFFAOYSA-N	50499310	CHEMBL3736433	Endothelin-1 receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499310&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034966	433911211							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51215062	CC(C)NCC(O)COc1cccc2ccccc12	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	AQHHHDLHHXJYJD-UHFFFAOYSA-N	25761	Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine	Endothelin-1 receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	SNP	1DY4,6EKZ,6PS5,5FUK	4946	56413049	8499	CHEMBL27	DB00571	564	C07407	ZINC00056556	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51215069	CC(C)NCC(O)COc1cccc2ccccc12	InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	AQHHHDLHHXJYJD-UHFFFAOYSA-N	25761	Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine	Endothelin-1 receptor			<5012							ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	SNP	1DY4,6EKZ,6PS5,5FUK	4946	56413049	8499	CHEMBL27	DB00571	564	C07407	ZINC00056556	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51215104	CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1	InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	KVVLFJLSBAOKPZ-UHFFFAOYSA-N	50499311	CHEMBL3736156	Endothelin-1 receptor					<5012					ChEMBL	10.1021/acs.jmedchem.5b01088	10.7270/Q21C20VP	26565745			Rombouts, FJ; Tovar, F; Austin, N; Tresadern, G; Trabanco, AA	Janssen Pharmaceutica N.V.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499311&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			127034967	433911212							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51263787	FC(F)Oc1ccc(NC(=O)NC2CCN(CC2)c2ncnc3n(c(nc23)-c2ccccc2Cl)-c2ccc(Cl)cc2)cn1	InChI=1S/C29H24Cl2F2N8O2/c30-17-5-8-20(9-6-17)41-25(21-3-1-2-4-22(21)31)39-24-26(35-16-36-27(24)41)40-13-11-18(12-14-40)37-29(42)38-19-7-10-23(34-15-19)43-28(32)33/h1-10,15-16,18,28H,11-14H2,(H2,37,38,42)	LTNOPYMLPTUXSM-UHFFFAOYSA-N	50516235	CHEMBL4563408	Endothelin-1 receptor					>10000					ChEMBL	10.1021/acs.jmedchem.9b00727	10.7270/Q24F1V3D	31185168			Amato, G; Manke, A; Wiethe, R; Vasukuttan, V; Snyder, R; Yueh, YL; Decker, A; Runyon, S; Maitra, R	RTI International	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			135156251	440724817							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51263840	FC(F)Oc1ccc(NC(=O)NC2CCN(CC2)c2ncnc3n(c(nc23)-c2ccccc2Cl)-c2ccc(Cl)cc2)cn1	InChI=1S/C29H24Cl2F2N8O2/c30-17-5-8-20(9-6-17)41-25(21-3-1-2-4-22(21)31)39-24-26(35-16-36-27(24)41)40-13-11-18(12-14-40)37-29(42)38-19-7-10-23(34-15-19)43-28(32)33/h1-10,15-16,18,28H,11-14H2,(H2,37,38,42)	LTNOPYMLPTUXSM-UHFFFAOYSA-N	50516235	CHEMBL4563408	Endothelin-1 receptor			>10000							ChEMBL	10.1021/acs.jmedchem.9b00727	10.7270/Q24F1V3D	31185168			Amato, G; Manke, A; Wiethe, R; Vasukuttan, V; Snyder, R; Yueh, YL; Decker, A; Runyon, S; Maitra, R	RTI International	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50516235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50516235&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			135156251	440724817							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51268645	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 1585							ChEMBL	10.1021/acs.jmedchem.8b00435	10.7270/Q2F76GX7	29939744			Tan, L; Yan, W; McCorvy, JD; Cheng, J	ShanghaiTech University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313790	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ccccc1	InChI=1S/C29H31N3O6S/c1-29(2,3)21-14-16-22(17-15-21)39(34,35)32-27-25(38-24-13-9-8-12-23(24)36-4)28(37-19-18-33)31-26(30-27)20-10-6-5-7-11-20/h5-17,33H,18-19H2,1-4H3,(H,30,31,32)	HVRDENHNEUGHGW-UHFFFAOYSA-N	50532556	CHEMBL4438132	Endothelin-1 receptor			 800							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532556&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19095644	440741138							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313792	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)[C@@H](c1ccc2OCOc2c1)n1nc(C)ccc1=O	InChI=1S/C23H23N3O6S/c1-14(2)16-5-8-18(9-6-16)33(29,30)25-23(28)22(26-21(27)11-4-15(3)24-26)17-7-10-19-20(12-17)32-13-31-19/h4-12,14,22H,13H2,1-3H3,(H,25,28)/t22-/m1/s1	LUQZWCBOERIKEO-JOCHJYFZSA-N	50532557	CHEMBL4435789	Endothelin-1 receptor			 29							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532557&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155511294	440741139							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313794	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCO)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34)	LFWCJABOXHSRGC-UHFFFAOYSA-N	50066370	5-Methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(2H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL109648::clazosentan	Endothelin-1 receptor			 1.7							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066370&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6433095	103961012		CHEMBL109648				ZINC26973408	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313796	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C28H25BrN8O6S/c1-40-21-10-5-6-11-22(21)43-23-24(37-44(38,39)34-16-19-8-3-2-4-9-19)35-26(25-30-12-7-13-31-25)36-27(23)41-14-15-42-28-32-17-20(29)18-33-28/h2-13,17-18,34H,14-16H2,1H3,(H,35,36,37)	MNRPBSOBVCAVNX-UHFFFAOYSA-N	50395650	CHEMBL2163716	Endothelin-1 receptor			 1.9							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395650&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456863	163344674		CHEMBL2163716				ZINC95552081	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313798	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C19H21ClN6O4S2/c1-3-25-32(27,28)26-17-16(13-4-6-14(20)7-5-13)18(24-12-23-17)29-8-9-30-19-21-10-15(31-2)11-22-19/h4-7,10-12,25H,3,8-9H2,1-2H3,(H,23,24,26)	FWIARXJRYJCABB-UHFFFAOYSA-N	50532560	CHEMBL4573273	Endothelin-1 receptor			 1.3							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532560&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			58688008	440741142							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313799	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC1CCCO1)-c1ccnc(c1)-c1noc(=S)[nH]1	InChI=1S/C29H27N7O7S2/c1-17-9-10-23(31-15-17)45(37,38)36-27-24(42-22-8-4-3-7-21(22)39-2)28(41-16-19-6-5-13-40-19)33-25(32-27)18-11-12-30-20(14-18)26-34-29(44)43-35-26/h3-4,7-12,14-15,19H,5-6,13,16H2,1-2H3,(H,32,33,36)(H,34,35,44)	YLJHCAFDKWQJPI-UHFFFAOYSA-N	50532561	CHEMBL4568468	Endothelin-1 receptor			 6.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532561&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44215416	440741143							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313800	NS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C16H14Br2N6O4S/c17-11-3-1-10(2-4-11)13-14(24-29(19,25)26)22-9-23-15(13)27-5-6-28-16-20-7-12(18)8-21-16/h1-4,7-9H,5-6H2,(H2,19,25,26)(H,22,23,24)	DKULOVKANLVDEA-UHFFFAOYSA-N	50395672	CHEMBL2165326	Endothelin-1 receptor			 3.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395672&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			25099191	163344696		CHEMBL2165326				ZINC95553608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313804	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCC1CCCO1)-c1ccnc(c1)-c1noc(=S)[nH]1	InChI=1S/C29H27N7O7S2/c1-17-9-10-23(31-15-17)45(37,38)36-27-24(42-22-8-4-3-7-21(22)39-2)28(41-16-19-6-5-13-40-19)33-25(32-27)18-11-12-30-20(14-18)26-34-29(44)43-35-26/h3-4,7-12,14-15,19H,5-6,13,16H2,1-2H3,(H,32,33,36)(H,34,35,44)	YLJHCAFDKWQJPI-UHFFFAOYSA-N	50532561	CHEMBL4568468	Endothelin-1 receptor			 6.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532561&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44215416	440741143							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313805	NS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C16H14Br2N6O4S/c17-11-3-1-10(2-4-11)13-14(24-29(19,25)26)22-9-23-15(13)27-5-6-28-16-20-7-12(18)8-21-16/h1-4,7-9H,5-6H2,(H2,19,25,26)(H,22,23,24)	DKULOVKANLVDEA-UHFFFAOYSA-N	50395672	CHEMBL2165326	Endothelin-1 receptor			 3.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395672&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			25099191	163344696		CHEMBL2165326				ZINC95553608	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313808	CC(C)c1ccc(cc1)S(=O)(=O)NC(=O)[C@@H](c1ccc2OCOc2c1)n1nc(C)ccc1=O	InChI=1S/C23H23N3O6S/c1-14(2)16-5-8-18(9-6-16)33(29,30)25-23(28)22(26-21(27)11-4-15(3)24-26)17-7-10-19-20(12-17)32-13-31-19/h4-12,14,22H,13H2,1-3H3,(H,25,28)/t22-/m1/s1	LUQZWCBOERIKEO-JOCHJYFZSA-N	50532557	CHEMBL4435789	Endothelin-1 receptor			 29							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532557&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155511294	440741139							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313811	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCO)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34)	LFWCJABOXHSRGC-UHFFFAOYSA-N	50066370	5-Methyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(2H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL109648::clazosentan	Endothelin-1 receptor			 1.7							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066370&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6433095	103961012		CHEMBL109648				ZINC26973408	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313813	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C19H21ClN6O4S2/c1-3-25-32(27,28)26-17-16(13-4-6-14(20)7-5-13)18(24-12-23-17)29-8-9-30-19-21-10-15(31-2)11-22-19/h4-7,10-12,25H,3,8-9H2,1-2H3,(H,23,24,26)	FWIARXJRYJCABB-UHFFFAOYSA-N	50532560	CHEMBL4573273	Endothelin-1 receptor			 1.3							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532560&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			58688008	440741142							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313814	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ccccc1	InChI=1S/C29H31N3O6S/c1-29(2,3)21-14-16-22(17-15-21)39(34,35)32-27-25(38-24-13-9-8-12-23(24)36-4)28(37-19-18-33)31-26(30-27)20-10-6-5-7-11-20/h5-17,33H,18-19H2,1-4H3,(H,30,31,32)	HVRDENHNEUGHGW-UHFFFAOYSA-N	50532556	CHEMBL4438132	Endothelin-1 receptor			 800							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532556&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19095644	440741138							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313816	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C28H25BrN8O6S/c1-40-21-10-5-6-11-22(21)43-23-24(37-44(38,39)34-16-19-8-3-2-4-9-19)35-26(25-30-12-7-13-31-25)36-27(23)41-14-15-42-28-32-17-20(29)18-33-28/h2-13,17-18,34H,14-16H2,1H3,(H,35,36,37)	MNRPBSOBVCAVNX-UHFFFAOYSA-N	50395650	CHEMBL2163716	Endothelin-1 receptor			 1.9							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395650&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71456863	163344674		CHEMBL2163716				ZINC95552081	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313820	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OC)-c1ccncc1	InChI=1S/C25H25N5O5S/c1-16(2)18-9-10-21(27-15-18)36(31,32)30-24-22(35-20-8-6-5-7-19(20)33-3)25(34-4)29-23(28-24)17-11-13-26-14-12-17/h5-16H,1-4H3,(H,28,29,30)	VGZZYWAKZYKCPI-UHFFFAOYSA-N	50532564	CHEMBL4456288	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532564&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18630945	440741146							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313821	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)C(=O)Nc1ccccc1	InChI=1S/C30H32N4O7S/c1-30(2,3)20-14-16-22(17-15-20)42(37,38)34-26-25(41-24-13-9-8-12-23(24)39-4)29(40-19-18-35)33-27(32-26)28(36)31-21-10-6-5-7-11-21/h5-17,35H,18-19H2,1-4H3,(H,31,36)(H,32,33,34)	ODOHYBAWFJRUBM-UHFFFAOYSA-N	50532565	CHEMBL4447655	Endothelin-1 receptor			 13000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532565&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44213959	440741147							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313823	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C29H26BrN7O6S/c1-40-22-10-5-6-11-23(22)43-24-25(37-44(38,39)17-12-20-8-3-2-4-9-20)35-27(26-31-13-7-14-32-26)36-28(24)41-15-16-42-29-33-18-21(30)19-34-29/h2-11,13-14,18-19H,12,15-17H2,1H3,(H,35,36,37)	DEOGRJUDPLWPSR-UHFFFAOYSA-N	50395664	CHEMBL2163702	Endothelin-1 receptor			 2.2							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395664&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23548253	163344688		CHEMBL2163702				ZINC95555792	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313825	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C20H23ClN6O4S2/c1-3-8-26-33(28,29)27-18-17(14-4-6-15(21)7-5-14)19(25-13-24-18)30-9-10-31-20-22-11-16(32-2)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	QRKZNZMLWQPCPE-UHFFFAOYSA-N	50532566	CHEMBL4436531	Endothelin-1 receptor			 1.5							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532566&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041297	440741148							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313826	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCCNS(=O)(=O)c1cccs1)C1CC1	InChI=1S/C29H33N5O7S3/c1-19(2)21-13-14-24(30-18-21)43(35,36)34-28-26(41-23-9-5-4-8-22(23)39-3)29(33-27(32-28)20-11-12-20)40-16-7-15-31-44(37,38)25-10-6-17-42-25/h4-6,8-10,13-14,17-20,31H,7,11-12,15-16H2,1-3H3,(H,32,33,34)	AEDJOIBTFWFFLB-UHFFFAOYSA-N	50124446	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(thiophene-2-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide::CHEMBL367444	Endothelin-1 receptor			 22							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124446&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9917706	104016761		CHEMBL367444				ZINC28019057	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313827	COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1	InChI=1S/C31H35N3O8S/c1-31(2,3)21-12-16-24(17-13-21)43(37,38)34-29-27(42-26-9-7-6-8-25(26)40-5)30(41-19-22(36)18-35)33-28(32-29)20-10-14-23(39-4)15-11-20/h6-17,22,35-36H,18-19H2,1-5H3,(H,32,33,34)/t22-/m1/s1	DRIHNVYRUGBDHI-JOCHJYFZSA-N	50532567	CHEMBL1628620::Ro-468443	Endothelin-1 receptor			 6800							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532567&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5312146	440741149							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313829	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OC)-c1ccncc1	InChI=1S/C25H25N5O5S/c1-16(2)18-9-10-21(27-15-18)36(31,32)30-24-22(35-20-8-6-5-7-19(20)33-3)25(34-4)29-23(28-24)17-11-13-26-14-12-17/h5-16H,1-4H3,(H,28,29,30)	VGZZYWAKZYKCPI-UHFFFAOYSA-N	50532564	CHEMBL4456288	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532564&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			18630945	440741146							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313832	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncc(Br)cn1)-c1ncccn1	InChI=1S/C29H26BrN7O6S/c1-40-22-10-5-6-11-23(22)43-24-25(37-44(38,39)17-12-20-8-3-2-4-9-20)35-27(26-31-13-7-14-32-26)36-28(24)41-15-16-42-29-33-18-21(30)19-34-29/h2-11,13-14,18-19H,12,15-17H2,1H3,(H,35,36,37)	DEOGRJUDPLWPSR-UHFFFAOYSA-N	50395664	CHEMBL2163702	Endothelin-1 receptor			 2.2							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395664&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23548253	163344688		CHEMBL2163702				ZINC95555792	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313833	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H21BrN6O4S2/c1-3-25-32(27,28)26-17-16(13-4-6-14(20)7-5-13)18(24-12-23-17)29-8-9-30-19-21-10-15(31-2)11-22-19/h4-7,10-12,25H,3,8-9H2,1-2H3,(H,23,24,26)	GADXZXTXFHEOKH-UHFFFAOYSA-N	50532568	CHEMBL4565926	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532568&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			58688005	440741150							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313834	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C20H23ClN6O4S2/c1-3-8-26-33(28,29)27-18-17(14-4-6-15(21)7-5-14)19(25-13-24-18)30-9-10-31-20-22-11-16(32-2)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	QRKZNZMLWQPCPE-UHFFFAOYSA-N	50532566	CHEMBL4436531	Endothelin-1 receptor			 1.5							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532566&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041297	440741148							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313835	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCCNS(=O)(=O)c1cccs1)C1CC1	InChI=1S/C29H33N5O7S3/c1-19(2)21-13-14-24(30-18-21)43(35,36)34-28-26(41-23-9-5-4-8-22(23)39-3)29(33-27(32-28)20-11-12-20)40-16-7-15-31-44(37,38)25-10-6-17-42-25/h4-6,8-10,13-14,17-20,31H,7,11-12,15-16H2,1-3H3,(H,32,33,34)	AEDJOIBTFWFFLB-UHFFFAOYSA-N	50124446	5-Isopropyl-pyridine-2-sulfonic acid {2-cyclopropyl-5-(2-methoxy-phenoxy)-6-[3-(thiophene-2-sulfonylamino)-propoxy]-pyrimidin-4-yl}-amide::CHEMBL367444	Endothelin-1 receptor			 22							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124446&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9917706	104016761		CHEMBL367444				ZINC28019057	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313837	OCCOc1ncnc(NS(=O)(=O)c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1	InChI=1S/C18H15Cl2N3O4S/c19-13-3-1-12(2-4-13)16-17(21-11-22-18(16)27-10-9-24)23-28(25,26)15-7-5-14(20)6-8-15/h1-8,11,24H,9-10H2,(H,21,22,23)	UVYRLSAIJAIUIA-UHFFFAOYSA-N	50532569	CHEMBL4455096	Endothelin-1 receptor			 10000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532569&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9846065	440741151							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313838	OCCOc1ncnc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c1-c1ccc(Cl)cc1	InChI=1S/C19H15ClF3N3O4S/c20-14-5-1-12(2-6-14)16-17(24-11-25-18(16)30-10-9-27)26-31(28,29)15-7-3-13(4-8-15)19(21,22)23/h1-8,11,27H,9-10H2,(H,24,25,26)	FLIPFJKRZXGNFY-UHFFFAOYSA-N	50532570	CHEMBL4590568	Endothelin-1 receptor			 18000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532570&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19735343	440741152							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313839	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C23H27N3O6S/c1-23(2,3)16-9-11-17(12-10-16)33(28,29)26-21-20(22(25-15-24-21)31-14-13-27)32-19-8-6-5-7-18(19)30-4/h5-12,15,27H,13-14H2,1-4H3,(H,24,25,26)	KPJXDJRWFUDSEA-UHFFFAOYSA-N	50532571	CHEMBL4525321	Endothelin-1 receptor			 1500							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532571&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10983585	440741153							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313840	CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1nc(nc(OCCO)c1Oc1ccccc1O)-c1ncccn1	InChI=1S/C26H27N5O6S/c1-26(2,3)17-9-11-18(12-10-17)38(34,35)31-22-21(37-20-8-5-4-7-19(20)33)25(36-16-15-32)30-24(29-22)23-27-13-6-14-28-23/h4-14,32-33H,15-16H2,1-3H3,(H,29,30,31)	STTLKJGYAWXIPP-UHFFFAOYSA-N	50532572	CHEMBL3956076	Endothelin-1 receptor			 26000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532572&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6426756	440741154							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313841	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc([nH]c1=O)-c1ncccn1	InChI=1S/C25H25N5O5S/c1-25(2,3)16-10-12-17(13-11-16)36(32,33)30-21-20(35-19-9-6-5-8-18(19)34-4)24(31)29-23(28-21)22-26-14-7-15-27-22/h5-15H,1-4H3,(H2,28,29,30,31)	REEANFGHAAWSIZ-UHFFFAOYSA-N	50532573	CHEMBL4545092	Endothelin-1 receptor			 133000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532573&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			135870740	440741155							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313842	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)-c1ncccn1	InChI=1S/C33H33N7O7S/c1-33(2,3)22-13-15-23(16-14-22)48(42,43)40-28-27(47-25-11-6-5-10-24(25)44-4)31(39-30(38-28)29-35-18-9-19-36-29)45-20-21-46-32(41)37-26-12-7-8-17-34-26/h5-19H,20-21H2,1-4H3,(H,34,37,41)(H,38,39,40)	RZTQQRCQEYQARM-UHFFFAOYSA-N	50290041	CHEMBL70203::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-ethyl ester	Endothelin-1 receptor			 6.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290041&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44212539	104131612		CHEMBL70203				ZINC03980528	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313848	COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCO)c1	InChI=1S/C23H27N3O6S/c1-23(2,3)16-8-10-19(11-9-16)33(28,29)26-21-20(22(25-15-24-21)31-13-12-27)32-18-7-5-6-17(14-18)30-4/h5-11,14-15,27H,12-13H2,1-4H3,(H,24,25,26)	ZNXOKLWCOWOECF-UHFFFAOYSA-N	50105015	4-(4-tert-Butyl-pyrimidin-1-yl)-N-(2-hydroxy-ethoxy)-3-(3-methoxy-phenoxy)-benzenesulfonamide::4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(3-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL115951::Ro-46-2005	Endothelin-1 receptor			 220							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105015&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122044	104000812		CHEMBL115951				ZINC01535471	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313850	COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(cc2OCCO)C(=O)Nc2ccccc2)c1	InChI=1S/C29H28N2O7S2/c1-36-22-9-6-10-23(19-22)38-28-26(31-40(34,35)25-13-11-24(39-2)12-14-25)17-20(18-27(28)37-16-15-32)29(33)30-21-7-4-3-5-8-21/h3-14,17-19,31-32H,15-16H2,1-2H3,(H,30,33)	TUVWXDAWMTZYAZ-UHFFFAOYSA-N	50532575	CHEMBL4438411	Endothelin-1 receptor			>100000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532575&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23288645	440741157							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313851	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)C)nc(nc1OCCO)C(F)(F)F	InChI=1S/C23H24F3N3O6S/c1-14(2)15-8-10-16(11-9-15)36(31,32)29-20-19(35-18-7-5-4-6-17(18)33-3)21(34-13-12-30)28-22(27-20)23(24,25)26/h4-11,14,30H,12-13H2,1-3H3,(H,27,28,29)	FKUFTGMFORIVAP-UHFFFAOYSA-N	50532576	CHEMBL4562189	Endothelin-1 receptor			 50							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532576&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9871561	440741158							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313852	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)cc(cc1OCCOC(=O)Nc1ccccn1)C(=O)N1CCN(C)CC1	InChI=1S/C35H40N6O8S/c1-24(2)25-12-13-32(37-23-25)50(44,45)39-27-21-26(34(42)41-17-15-40(3)16-18-41)22-30(33(27)49-29-10-6-5-9-28(29)46-4)47-19-20-48-35(43)38-31-11-7-8-14-36-31/h5-14,21-24,39H,15-20H2,1-4H3,(H,36,38,43)	GKCAKABSOVLWHG-UHFFFAOYSA-N	50532574	CHEMBL4579445	Endothelin-1 receptor			 10.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532574&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9939960	440741156							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313853	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCO)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C27H27N9O6S/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37H,12-13H2,1-3H3,(H,30,31,34)(H,32,33,35,36)	TUYWTLTWNJOZNY-UHFFFAOYSA-N	50143800	5-Isopropyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL61780::TEZOSENTAN	Endothelin-1 receptor			 18							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143800&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			151174	104032960		CHEMBL61780				ZINC26143524	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313854	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1	InChI=1S/C23H21N5O5S/c1-15-8-9-19(25-14-15)34(29,30)28-22-20(33-18-7-5-4-6-17(18)31-2)23(32-3)27-21(26-22)16-10-12-24-13-11-16/h4-14H,1-3H3,(H,26,27,28)	YBWLTKFZAOSWSM-UHFFFAOYSA-N	50532577	Avosentan::RO 67-0565::RO-67-0565::Ro670565::SPP-301::SPP301	Endothelin-1 receptor			 3.1							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532577&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9912992	440741159							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313862	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCO)-c1ncccn1	InChI=1S/C25H25N5O6S/c1-34-19-10-5-6-11-20(19)36-21-22(30-37(32,33)17-12-18-8-3-2-4-9-18)28-24(23-26-13-7-14-27-23)29-25(21)35-16-15-31/h2-11,13-14,31H,12,15-17H2,1H3,(H,28,29,30)	NGLUZGYJAMFNPH-UHFFFAOYSA-N	50395671	CHEMBL2163695	Endothelin-1 receptor			 25							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395671&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10218058	163344695		CHEMBL2163695				ZINC38391116	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313863	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncccn1)-c1ncccn1	InChI=1S/C29H27N7O6S/c1-39-22-11-5-6-12-23(22)42-24-25(36-43(37,38)20-13-21-9-3-2-4-10-21)34-27(26-30-14-7-15-31-26)35-28(24)40-18-19-41-29-32-16-8-17-33-29/h2-12,14-17H,13,18-20H2,1H3,(H,34,35,36)	WSNWXTKIOPWVDW-UHFFFAOYSA-N	50395668	CHEMBL2163698	Endothelin-1 receptor			 8.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395668&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10145418	163344692		CHEMBL2163698				ZINC95554443	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313864	CCCCS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C25H26BrN7O6S/c1-3-4-14-40(34,35)33-21-20(39-19-9-6-5-8-18(19)36-2)24(32-23(31-21)22-27-10-7-11-28-22)37-12-13-38-25-29-15-17(26)16-30-25/h5-11,15-16H,3-4,12-14H2,1-2H3,(H,31,32,33)	YPXSZXRASAVIKK-UHFFFAOYSA-N	50395651	CHEMBL2163715	Endothelin-1 receptor			 4.3							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395651&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451528	163344675		CHEMBL2163715				ZINC95552921	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313870	CNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C18H19BrN6O4S2/c1-20-31(26,27)25-16-15(12-3-5-13(19)6-4-12)17(24-11-23-16)28-7-8-29-18-21-9-14(30-2)10-22-18/h3-6,9-11,20H,7-8H2,1-2H3,(H,23,24,25)	KSGHGYRWLMKYNA-UHFFFAOYSA-N	50532580	CHEMBL4540866	Endothelin-1 receptor			 2.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532580&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041288	440741162							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313871	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H23BrN6O4S2/c1-3-8-26-33(28,29)27-18-17(14-4-6-15(21)7-5-14)19(25-13-24-18)30-9-10-31-20-22-11-16(32-2)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	LDYLIYKANSSERK-UHFFFAOYSA-N	50532581	CHEMBL4467748	Endothelin-1 receptor			 0.100000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532581&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041278	440741163							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313872	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(OC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C21H25BrN6O5S/c1-3-4-9-27-34(29,30)28-19-18(15-5-7-16(22)8-6-15)20(26-14-25-19)32-10-11-33-21-23-12-17(31-2)13-24-21/h5-8,12-14,27H,3-4,9-11H2,1-2H3,(H,25,26,28)	ZWTAXWXITAZUQP-UHFFFAOYSA-N	50532582	CHEMBL4521348	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532582&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041283	440741164							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313873	CNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C18H19ClN6O4S2/c1-20-31(26,27)25-16-15(12-3-5-13(19)6-4-12)17(24-11-23-16)28-7-8-29-18-21-9-14(30-2)10-22-18/h3-6,9-11,20H,7-8H2,1-2H3,(H,23,24,25)	HLYUXTAHAPGOGF-UHFFFAOYSA-N	50532558	CHEMBL4566095	Endothelin-1 receptor			 3.3							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041307	440741140							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313874	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C21H25ClN6O4S2/c1-3-4-9-27-34(29,30)28-19-18(15-5-7-16(22)8-6-15)20(26-14-25-19)31-10-11-32-21-23-12-17(33-2)13-24-21/h5-8,12-14,27H,3-4,9-11H2,1-2H3,(H,25,26,28)	IUTFNAAZZLIBQX-UHFFFAOYSA-N	50532583	CHEMBL4458005	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532583&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			58688006	440741165							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313875	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1Oc1ccccc1OC	InChI=1S/C21H26N6O6S2/c1-4-9-26-35(28,29)27-19-18(33-17-8-6-5-7-16(17)30-2)20(25-14-24-19)31-10-11-32-21-22-12-15(34-3)13-23-21/h5-8,12-14,26H,4,9-11H2,1-3H3,(H,24,25,27)	OGTVYDGVOOLHDI-UHFFFAOYSA-N	50532584	CHEMBL4444355	Endothelin-1 receptor			 9.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532584&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155517241	440741166							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313877	OCCOc1ncnc(NS(=O)(=O)c2ccc(Cl)cc2)c1-c1ccc(Cl)cc1	InChI=1S/C18H15Cl2N3O4S/c19-13-3-1-12(2-4-13)16-17(21-11-22-18(16)27-10-9-24)23-28(25,26)15-7-5-14(20)6-8-15/h1-8,11,24H,9-10H2,(H,21,22,23)	UVYRLSAIJAIUIA-UHFFFAOYSA-N	50532569	CHEMBL4455096	Endothelin-1 receptor			 10000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532569&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9846065	440741151							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313878	OCCOc1ncnc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c1-c1ccc(Cl)cc1	InChI=1S/C19H15ClF3N3O4S/c20-14-5-1-12(2-6-14)16-17(24-11-25-18(16)30-10-9-27)26-31(28,29)15-7-3-13(4-8-15)19(21,22)23/h1-8,11,27H,9-10H2,(H,24,25,26)	FLIPFJKRZXGNFY-UHFFFAOYSA-N	50532570	CHEMBL4590568	Endothelin-1 receptor			 18000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532570&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19735343	440741152							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313879	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C23H27N3O6S/c1-23(2,3)16-9-11-17(12-10-16)33(28,29)26-21-20(22(25-15-24-21)31-14-13-27)32-19-8-6-5-7-18(19)30-4/h5-12,15,27H,13-14H2,1-4H3,(H,24,25,26)	KPJXDJRWFUDSEA-UHFFFAOYSA-N	50532571	CHEMBL4525321	Endothelin-1 receptor			 1500							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532571&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10983585	440741153							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313880	CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1nc(nc(OCCO)c1Oc1ccccc1O)-c1ncccn1	InChI=1S/C26H27N5O6S/c1-26(2,3)17-9-11-18(12-10-17)38(34,35)31-22-21(37-20-8-5-4-7-19(20)33)25(36-16-15-32)30-24(29-22)23-27-13-6-14-28-23/h4-14,32-33H,15-16H2,1-3H3,(H,29,30,31)	STTLKJGYAWXIPP-UHFFFAOYSA-N	50532572	CHEMBL3956076	Endothelin-1 receptor			 26000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532572&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6426756	440741154							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313881	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc([nH]c1=O)-c1ncccn1	InChI=1S/C25H25N5O5S/c1-25(2,3)16-10-12-17(13-11-16)36(32,33)30-21-20(35-19-9-6-5-8-18(19)34-4)24(31)29-23(28-21)22-26-14-7-15-27-22/h5-15H,1-4H3,(H2,28,29,30,31)	REEANFGHAAWSIZ-UHFFFAOYSA-N	50532573	CHEMBL4545092	Endothelin-1 receptor			 133000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532573&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			135870740	440741155							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313882	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCOC(=O)Nc1ccccn1)-c1ncccn1	InChI=1S/C33H33N7O7S/c1-33(2,3)22-13-15-23(16-14-22)48(42,43)40-28-27(47-25-11-6-5-10-24(25)44-4)31(39-30(38-28)29-35-18-9-19-36-29)45-20-21-46-32(41)37-26-12-7-8-17-34-26/h5-19H,20-21H2,1-4H3,(H,34,37,41)(H,38,39,40)	RZTQQRCQEYQARM-UHFFFAOYSA-N	50290041	CHEMBL70203::Pyridin-2-yl-carbamic acid 2-[6-(4-tert-butyl-benzenesulfonylamino)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yloxy]-ethyl ester	Endothelin-1 receptor			 6.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290041&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44212539	104131612		CHEMBL70203				ZINC03980528	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313888	COc1cccc(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)ncnc2OCCO)c1	InChI=1S/C23H27N3O6S/c1-23(2,3)16-8-10-19(11-9-16)33(28,29)26-21-20(22(25-15-24-21)31-13-12-27)32-18-7-5-6-17(14-18)30-4/h5-11,14-15,27H,12-13H2,1-4H3,(H,24,25,26)	ZNXOKLWCOWOECF-UHFFFAOYSA-N	50105015	4-(4-tert-Butyl-pyrimidin-1-yl)-N-(2-hydroxy-ethoxy)-3-(3-methoxy-phenoxy)-benzenesulfonamide::4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-(3-methoxy-phenoxy)-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL115951::Ro-46-2005	Endothelin-1 receptor			 220							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105015&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			122044	104000812		CHEMBL115951				ZINC01535471	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313889	COc1cccc(Oc2c(NS(=O)(=O)c3ccc(SC)cc3)cc(cc2OCCO)C(=O)Nc2ccccc2)c1	InChI=1S/C29H28N2O7S2/c1-36-22-9-6-10-23(19-22)38-28-26(31-40(34,35)25-13-11-24(39-2)12-14-25)17-20(18-27(28)37-16-15-32)29(33)30-21-7-4-3-5-8-21/h3-14,17-19,31-32H,15-16H2,1-2H3,(H,30,33)	TUVWXDAWMTZYAZ-UHFFFAOYSA-N	50532575	CHEMBL4438411	Endothelin-1 receptor			>100000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532575&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			23288645	440741157							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313890	COc1ccc(Cl)c(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)nc(nc2OCCO)N2CCOCC2)c1	InChI=1S/C27H33ClN4O7S/c1-27(2,3)18-5-8-20(9-6-18)40(34,35)31-24-23(39-22-17-19(36-4)7-10-21(22)28)25(38-16-13-33)30-26(29-24)32-11-14-37-15-12-32/h5-10,17,33H,11-16H2,1-4H3,(H,29,30,31)	SNNWVBKDKWUMGJ-UHFFFAOYSA-N	50532585	CHEMBL4447261	Endothelin-1 receptor			 35							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532585&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155519245	440741167							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313891	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)C)nc(nc1OCCO)C(F)(F)F	InChI=1S/C23H24F3N3O6S/c1-14(2)15-8-10-16(11-9-15)36(31,32)29-20-19(35-18-7-5-4-6-17(18)33-3)21(34-13-12-30)28-22(27-20)23(24,25)26/h4-11,14,30H,12-13H2,1-3H3,(H,27,28,29)	FKUFTGMFORIVAP-UHFFFAOYSA-N	50532576	CHEMBL4562189	Endothelin-1 receptor			 50							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532576&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9871561	440741158							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313892	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)cc(cc1OCCOC(=O)Nc1ccccn1)C(=O)N1CCN(C)CC1	InChI=1S/C35H40N6O8S/c1-24(2)25-12-13-32(37-23-25)50(44,45)39-27-21-26(34(42)41-17-15-40(3)16-18-41)22-30(33(27)49-29-10-6-5-9-28(29)46-4)47-19-20-48-35(43)38-31-11-7-8-14-36-31/h5-14,21-24,39H,15-20H2,1-4H3,(H,36,38,43)	GKCAKABSOVLWHG-UHFFFAOYSA-N	50532574	CHEMBL4579445	Endothelin-1 receptor			 10.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532574&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9939960	440741156							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313893	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCCO)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C27H27N9O6S/c1-16(2)18-8-9-22(29-15-18)43(38,39)34-26-23(42-21-7-5-4-6-20(21)40-3)27(41-13-12-37)31-24(30-26)17-10-11-28-19(14-17)25-32-35-36-33-25/h4-11,14-16,37H,12-13H2,1-3H3,(H,30,31,34)(H,32,33,35,36)	TUYWTLTWNJOZNY-UHFFFAOYSA-N	50143800	5-Isopropyl-pyridine-2-sulfonic acid {6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-[2-(1H-tetrazol-5-yl)-pyridin-4-yl]-pyrimidin-4-yl}-amide::CHEMBL61780::TEZOSENTAN	Endothelin-1 receptor			 18							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143800&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			151174	104032960		CHEMBL61780				ZINC26143524	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313894	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1	InChI=1S/C23H21N5O5S/c1-15-8-9-19(25-14-15)34(29,30)28-22-20(33-18-7-5-4-6-17(18)31-2)23(32-3)27-21(26-22)16-10-12-24-13-11-16/h4-14H,1-3H3,(H,26,27,28)	YBWLTKFZAOSWSM-UHFFFAOYSA-N	50532577	Avosentan::RO 67-0565::RO-67-0565::Ro670565::SPP-301::SPP301	Endothelin-1 receptor			 3.1							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532577&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9912992	440741159							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313899	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC	InChI=1S/C20H23BrN6O6S/c1-3-8-26-34(28,29)27-18-17(33-16-7-5-4-6-15(16)30-2)19(25-13-24-18)31-9-10-32-20-22-11-14(21)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	YORZLWSRXAEWRI-UHFFFAOYSA-N	50532586	CHEMBL4570529	Endothelin-1 receptor			 15							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532586&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155562688	440741168							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313900	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1Oc1cccc(OC)c1	InChI=1S/C21H26N6O6S2/c1-4-8-26-35(28,29)27-19-18(33-16-7-5-6-15(11-16)30-2)20(25-14-24-19)31-9-10-32-21-22-12-17(34-3)13-23-21/h5-7,11-14,26H,4,8-10H2,1-3H3,(H,24,25,27)	VNLAEVZRIYGZCY-UHFFFAOYSA-N	50532587	CHEMBL4519822	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532587&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155542285	440741169							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313901	CCCNS(=O)(=O)Nc1ncnc(OCCOc2cc(OC)ccc2Cl)c1-c1ncc(SC)cn1	InChI=1S/C21H25ClN6O5S2/c1-4-7-27-35(29,30)28-20-18(19-23-11-15(34-3)12-24-19)21(26-13-25-20)33-9-8-32-17-10-14(31-2)5-6-16(17)22/h5-6,10-13,27H,4,7-9H2,1-3H3,(H,25,26,28)	TYLZGSIGPRVNQJ-UHFFFAOYSA-N	50532562	CHEMBL4528516	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532562&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155544917	440741144							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313902	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CC)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C31H30N8O5S/c1-6-7-18-43-30-26(44-25-11-9-8-10-24(25)42-5)29(37-45(40,41)22-14-12-21(13-15-22)31(2,3)4)33-27(34-30)20-16-17-32-23(19-20)28-35-38-39-36-28/h8-17,19H,18H2,1-5H3,(H,33,34,37)(H,35,36,38,39)	QPUBINGNDLKIHN-UHFFFAOYSA-N	50532588	CHEMBL4465332	Endothelin-1 receptor			 33							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532588&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70240112	440741170							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313903	Cc1ccc(cc1)-c1c(NS(=O)(=O)\C=C\c2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C25H22BrN5O4S/c1-18-7-9-20(10-8-18)22-23(31-36(32,33)14-11-19-5-3-2-4-6-19)29-17-30-24(22)34-12-13-35-25-27-15-21(26)16-28-25/h2-11,14-17H,12-13H2,1H3,(H,29,30,31)/b14-11+	RPBOIJRVAJKCSF-SDNWHVSQSA-N	50532589	CHEMBL4573806	Endothelin-1 receptor			 2.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532589&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9829478	440741171							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313904	COc1ccccc1Oc1c(NS(=O)(=O)CCc2cccs2)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C29H32N6O8S2/c1-39-22-8-2-3-9-23(22)43-25-26(34-45(37,38)20-11-21-7-6-19-44-21)32-28(35-13-15-40-16-14-35)33-27(25)41-17-18-42-29(36)31-24-10-4-5-12-30-24/h2-10,12,19H,11,13-18,20H2,1H3,(H,30,31,36)(H,32,33,34)	NONLTBWVEZEZFY-UHFFFAOYSA-N	50532590	CHEMBL4549357	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532590&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10146305	440741172							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313905	COCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H23BrN6O5S2/c1-30-8-7-26-34(28,29)27-18-17(14-3-5-15(21)6-4-14)19(25-13-24-18)31-9-10-32-20-22-11-16(33-2)12-23-20/h3-6,11-13,26H,7-10H2,1-2H3,(H,24,25,27)	GAZYTXSFOKMUAC-UHFFFAOYSA-N	50532563	CHEMBL4553625	Endothelin-1 receptor			 0.200000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532563&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11757759	440741145							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313906	OC(=O)CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H18Br2N6O6S/c20-13-3-1-12(2-4-13)16-17(27-34(30,31)26-6-5-15(28)29)24-11-25-18(16)32-7-8-33-19-22-9-14(21)10-23-19/h1-4,9-11,26H,5-8H2,(H,28,29)(H,24,25,27)	YNKZURRWQXRKDP-UHFFFAOYSA-N	50532591	CHEMBL4463633	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532591&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11505449	440741173							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313907	CC(C)Oc1ccc2OC(C(C(O)=O)=C(c3ccc(C)s3)c2c1)c1ccc2OCOc2c1	InChI=1S/C25H22O6S/c1-13(2)30-16-6-8-18-17(11-16)22(21-9-4-14(3)32-21)23(25(26)27)24(31-18)15-5-7-19-20(10-15)29-12-28-19/h4-11,13,24H,12H2,1-3H3,(H,26,27)	FSKVJGRQYIHVTI-UHFFFAOYSA-N	50112718	2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(5-methyl-thiophen-2-yl)-2H-chromene-3-carboxylic acid::CHEMBL293012	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112718&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9868379	104007116		CHEMBL293012				ZINC13473490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313908	CCc1cc(cc2OCOc12)C1=C(N(c2ccccc2C(F)(F)F)S(=O)(=O)c2ccccc12)C(O)=O	InChI=1S/C25H18F3NO6S/c1-2-14-11-15(12-19-23(14)35-13-34-19)21-16-7-3-6-10-20(16)36(32,33)29(22(21)24(30)31)18-9-5-4-8-17(18)25(26,27)28/h3-12H,2,13H2,1H3,(H,30,31)	YMGQBWRXNCAABF-UHFFFAOYSA-N	50532592	Fandosentan	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532592&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			157574	440741174							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313909	COc1cc(OC)nc(O[C@H](C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C22H22N2O6/c1-27-17-14-18(28-2)24-21(23-17)30-19(20(25)26)22(29-3,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1	FEJVSJIALLTFRP-LJQANCHMSA-N	50108202	(S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL23261::Darusentan	Endothelin-1 receptor		 6.0								ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			177236	104003423		CHEMBL23261	DB04883	3508		ZINC03826221	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313910	CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1nc(C)cc(C)n1)C(O)=O)c1ccccc1	InChI=1S/C24H24N4O4/c1-15-13-16(2)27-23(26-15)32-21(22(30)31)24(17-9-5-4-6-10-17)18-11-7-8-12-19(18)28(3)20(29)14-25-24/h4-13,21,25H,14H2,1-3H3,(H,30,31)/t21-,24+/m1/s1	FINMPMBYTTVLPJ-QPPBQGQZSA-N	50146654	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL330425	Endothelin-1 receptor			 12							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146654&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10224745	104035243		CHEMBL330425				ZINC13561023	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313911	COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(cc1)-c1nnco1	InChI=1S/C19H16N6O4S/c1-12-10-21-17(19(23-12)28-2)25-30(26,27)15-4-3-9-20-16(15)13-5-7-14(8-6-13)18-24-22-11-29-18/h3-11H,1-2H3,(H,21,25)	FJHHZXWJVIEFGJ-UHFFFAOYSA-N	50532593	ZD-4054::ZD4054::Zibotentan	Endothelin-1 receptor			 21							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532593&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9910224	440741175							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313934	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCO)-c1ncccn1	InChI=1S/C25H25N5O6S/c1-34-19-10-5-6-11-20(19)36-21-22(30-37(32,33)17-12-18-8-3-2-4-9-18)28-24(23-26-13-7-14-27-23)29-25(21)35-16-15-31/h2-11,13-14,31H,12,15-17H2,1H3,(H,28,29,30)	NGLUZGYJAMFNPH-UHFFFAOYSA-N	50395671	CHEMBL2163695	Endothelin-1 receptor			 25							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395671&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10218058	163344695		CHEMBL2163695				ZINC38391116	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313935	COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(nc1OCCOc1ncccn1)-c1ncccn1	InChI=1S/C29H27N7O6S/c1-39-22-11-5-6-12-23(22)42-24-25(36-43(37,38)20-13-21-9-3-2-4-10-21)34-27(26-30-14-7-15-31-26)35-28(24)40-18-19-41-29-32-16-8-17-33-29/h2-12,14-17H,13,18-20H2,1H3,(H,34,35,36)	WSNWXTKIOPWVDW-UHFFFAOYSA-N	50395668	CHEMBL2163698	Endothelin-1 receptor			 8.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395668&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10145418	163344692		CHEMBL2163698				ZINC95554443	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313936	CCCCS(=O)(=O)Nc1nc(nc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC)-c1ncccn1	InChI=1S/C25H26BrN7O6S/c1-3-4-14-40(34,35)33-21-20(39-19-9-6-5-8-18(19)36-2)24(32-23(31-21)22-27-10-7-11-28-22)37-12-13-38-25-29-15-17(26)16-30-25/h5-11,15-16H,3-4,12-14H2,1-2H3,(H,31,32,33)	YPXSZXRASAVIKK-UHFFFAOYSA-N	50395651	CHEMBL2163715	Endothelin-1 receptor			 4.3							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395651&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71451528	163344675		CHEMBL2163715				ZINC95552921	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313942	CNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C18H19BrN6O4S2/c1-20-31(26,27)25-16-15(12-3-5-13(19)6-4-12)17(24-11-23-16)28-7-8-29-18-21-9-14(30-2)10-22-18/h3-6,9-11,20H,7-8H2,1-2H3,(H,23,24,25)	KSGHGYRWLMKYNA-UHFFFAOYSA-N	50532580	CHEMBL4540866	Endothelin-1 receptor			 2.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532580&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041288	440741162							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313943	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H23BrN6O4S2/c1-3-8-26-33(28,29)27-18-17(14-4-6-15(21)7-5-14)19(25-13-24-18)30-9-10-31-20-22-11-16(32-2)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	LDYLIYKANSSERK-UHFFFAOYSA-N	50532581	CHEMBL4467748	Endothelin-1 receptor			 0.100000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532581&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041278	440741163							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313944	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(OC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C21H25BrN6O5S/c1-3-4-9-27-34(29,30)28-19-18(15-5-7-16(22)8-6-15)20(26-14-25-19)32-10-11-33-21-23-12-17(31-2)13-24-21/h5-8,12-14,27H,3-4,9-11H2,1-2H3,(H,25,26,28)	ZWTAXWXITAZUQP-UHFFFAOYSA-N	50532582	CHEMBL4521348	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532582&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041283	440741164							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313945	CNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C18H19ClN6O4S2/c1-20-31(26,27)25-16-15(12-3-5-13(19)6-4-12)17(24-11-23-16)28-7-8-29-18-21-9-14(30-2)10-22-18/h3-6,9-11,20H,7-8H2,1-2H3,(H,23,24,25)	HLYUXTAHAPGOGF-UHFFFAOYSA-N	50532558	CHEMBL4566095	Endothelin-1 receptor			 3.3							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532558&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041307	440741140							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313946	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C21H25ClN6O4S2/c1-3-4-9-27-34(29,30)28-19-18(15-5-7-16(22)8-6-15)20(26-14-25-19)31-10-11-32-21-23-12-17(33-2)13-24-21/h5-8,12-14,27H,3-4,9-11H2,1-2H3,(H,25,26,28)	IUTFNAAZZLIBQX-UHFFFAOYSA-N	50532583	CHEMBL4458005	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532583&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			58688006	440741165							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313947	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1Oc1ccccc1OC	InChI=1S/C21H26N6O6S2/c1-4-9-26-35(28,29)27-19-18(33-17-8-6-5-7-16(17)30-2)20(25-14-24-19)31-10-11-32-21-22-12-15(34-3)13-23-21/h5-8,12-14,26H,4,9-11H2,1-3H3,(H,24,25,27)	OGTVYDGVOOLHDI-UHFFFAOYSA-N	50532584	CHEMBL4444355	Endothelin-1 receptor			 9.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532584&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155517241	440741166							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313948	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1Oc1ccccc1OC	InChI=1S/C20H23BrN6O6S/c1-3-8-26-34(28,29)27-18-17(33-16-7-5-4-6-15(16)30-2)19(25-13-24-18)31-9-10-32-20-22-11-14(21)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	YORZLWSRXAEWRI-UHFFFAOYSA-N	50532586	CHEMBL4570529	Endothelin-1 receptor			 15							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532586&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155562688	440741168							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313949	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1Oc1cccc(OC)c1	InChI=1S/C21H26N6O6S2/c1-4-8-26-35(28,29)27-19-18(33-16-7-5-6-15(11-16)30-2)20(25-14-24-19)31-9-10-32-21-22-12-17(34-3)13-23-21/h5-7,11-14,26H,4,8-10H2,1-3H3,(H,24,25,27)	VNLAEVZRIYGZCY-UHFFFAOYSA-N	50532587	CHEMBL4519822	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532587&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155542285	440741169							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313950	CCCNS(=O)(=O)Nc1ncnc(OCCOc2cc(OC)ccc2Cl)c1-c1ncc(SC)cn1	InChI=1S/C21H25ClN6O5S2/c1-4-7-27-35(29,30)28-20-18(19-23-11-15(34-3)12-24-19)21(26-13-25-20)33-9-8-32-17-10-14(31-2)5-6-16(17)22/h5-6,10-13,27H,4,7-9H2,1-3H3,(H,25,26,28)	TYLZGSIGPRVNQJ-UHFFFAOYSA-N	50532562	CHEMBL4528516	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532562&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155544917	440741144							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313951	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)	JGCMEBMXRHSZKX-UHFFFAOYSA-N	50395626	ACT-064992::MACITENTAN	Endothelin-1 receptor			 3.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395626&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16004692	163344650			DB08932			ZINC43202140	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313955	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCC#CC)-c1ccnc(c1)-c1nnn[nH]1	InChI=1S/C31H30N8O5S/c1-6-7-18-43-30-26(44-25-11-9-8-10-24(25)42-5)29(37-45(40,41)22-14-12-21(13-15-22)31(2,3)4)33-27(34-30)20-16-17-32-23(19-20)28-35-38-39-36-28/h8-17,19H,18H2,1-5H3,(H,33,34,37)(H,35,36,38,39)	QPUBINGNDLKIHN-UHFFFAOYSA-N	50532588	CHEMBL4465332	Endothelin-1 receptor			 33							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532588&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			70240112	440741170							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313956	Cc1ccc(cc1)-c1c(NS(=O)(=O)\C=C\c2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C25H22BrN5O4S/c1-18-7-9-20(10-8-18)22-23(31-36(32,33)14-11-19-5-3-2-4-6-19)29-17-30-24(22)34-12-13-35-25-27-15-21(26)16-28-25/h2-11,14-17H,12-13H2,1H3,(H,29,30,31)/b14-11+	RPBOIJRVAJKCSF-SDNWHVSQSA-N	50532589	CHEMBL4573806	Endothelin-1 receptor			 2.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532589&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9829478	440741171							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313957	COc1ccccc1Oc1c(NS(=O)(=O)CCc2cccs2)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C29H32N6O8S2/c1-39-22-8-2-3-9-23(22)43-25-26(34-45(37,38)20-11-21-7-6-19-44-21)32-28(35-13-15-40-16-14-35)33-27(25)41-17-18-42-29(36)31-24-10-4-5-12-30-24/h2-10,12,19H,11,13-18,20H2,1H3,(H,30,31,36)(H,32,33,34)	NONLTBWVEZEZFY-UHFFFAOYSA-N	50532590	CHEMBL4549357	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532590&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10146305	440741172							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313958	COCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H23BrN6O5S2/c1-30-8-7-26-34(28,29)27-18-17(14-3-5-15(21)6-4-14)19(25-13-24-18)31-9-10-32-20-22-11-16(33-2)12-23-20/h3-6,11-13,26H,7-10H2,1-2H3,(H,24,25,27)	GAZYTXSFOKMUAC-UHFFFAOYSA-N	50532563	CHEMBL4553625	Endothelin-1 receptor			 0.200000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532563&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11757759	440741145							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313959	OC(=O)CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H18Br2N6O6S/c20-13-3-1-12(2-4-13)16-17(27-34(30,31)26-6-5-15(28)29)24-11-25-18(16)32-7-8-33-19-22-9-14(21)10-23-19/h1-4,9-11,26H,5-8H2,(H,28,29)(H,24,25,27)	YNKZURRWQXRKDP-UHFFFAOYSA-N	50532591	CHEMBL4463633	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532591&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			11505449	440741173							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313960	CC(C)Oc1ccc2OC(C(C(O)=O)=C(c3ccc(C)s3)c2c1)c1ccc2OCOc2c1	InChI=1S/C25H22O6S/c1-13(2)30-16-6-8-18-17(11-16)22(21-9-4-14(3)32-21)23(25(26)27)24(31-18)15-5-7-19-20(10-15)29-12-28-19/h4-11,13,24H,12H2,1-3H3,(H,26,27)	FSKVJGRQYIHVTI-UHFFFAOYSA-N	50112718	2-Benzo[1,3]dioxol-5-yl-6-isopropoxy-4-(5-methyl-thiophen-2-yl)-2H-chromene-3-carboxylic acid::CHEMBL293012	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50112718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50112718&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9868379	104007116		CHEMBL293012				ZINC13473490	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313961	CCc1cc(cc2OCOc12)C1=C(N(c2ccccc2C(F)(F)F)S(=O)(=O)c2ccccc12)C(O)=O	InChI=1S/C25H18F3NO6S/c1-2-14-11-15(12-19-23(14)35-13-34-19)21-16-7-3-6-10-20(16)36(32,33)29(22(21)24(30)31)18-9-5-4-8-17(18)25(26,27)28/h3-12H,2,13H2,1H3,(H,30,31)	YMGQBWRXNCAABF-UHFFFAOYSA-N	50532592	Fandosentan	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532592&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			157574	440741174							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313962	COc1cc(OC)nc(O[C@H](C(O)=O)C(OC)(c2ccccc2)c2ccccc2)n1	InChI=1S/C22H22N2O6/c1-27-17-14-18(28-2)24-21(23-17)30-19(20(25)26)22(29-3,15-10-6-4-7-11-15)16-12-8-5-9-13-16/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1	FEJVSJIALLTFRP-LJQANCHMSA-N	50108202	(S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::CHEMBL23261::Darusentan	Endothelin-1 receptor		 6.0								ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108202&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			177236	104003423		CHEMBL23261	DB04883	3508		ZINC03826221	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313963	CN1c2ccccc2[C@](NCC1=O)([C@H](Oc1nc(C)cc(C)n1)C(O)=O)c1ccccc1	InChI=1S/C24H24N4O4/c1-15-13-16(2)27-23(26-15)32-21(22(30)31)24(17-9-5-4-6-10-17)18-11-7-8-12-19(18)28(3)20(29)14-25-24/h4-13,21,25H,14H2,1-3H3,(H,30,31)/t21-,24+/m1/s1	FINMPMBYTTVLPJ-QPPBQGQZSA-N	50146654	(S)-(4,6-Dimethyl-pyrimidin-2-yloxy)-((S)-1-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-5-yl)-acetic acid::CHEMBL330425	Endothelin-1 receptor			 12							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146654&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10224745	104035243		CHEMBL330425				ZINC13561023	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313964	COc1nc(C)cnc1NS(=O)(=O)c1cccnc1-c1ccc(cc1)-c1nnco1	InChI=1S/C19H16N6O4S/c1-12-10-21-17(19(23-12)28-2)25-30(26,27)15-4-3-9-20-16(15)13-5-7-14(8-6-13)18-24-22-11-29-18/h3-11H,1-2H3,(H,21,25)	FJHHZXWJVIEFGJ-UHFFFAOYSA-N	50532593	ZD-4054::ZD4054::Zibotentan	Endothelin-1 receptor			 21							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532593&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9910224	440741175							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313984	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)	JGCMEBMXRHSZKX-UHFFFAOYSA-N	50395626	ACT-064992::MACITENTAN	Endothelin-1 receptor			 3.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395626&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16004692	163344650			DB08932			ZINC43202140	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313988	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 45							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313990	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)C)nc(nc1OCCO)C(F)(F)F	InChI=1S/C23H24F3N3O6S/c1-14(2)15-8-10-16(11-9-15)36(31,32)29-20-19(35-18-7-5-4-6-17(18)33-3)21(34-13-12-30)28-22(27-20)23(24,25)26/h4-11,14,30H,12-13H2,1-3H3,(H,27,28,29)	FKUFTGMFORIVAP-UHFFFAOYSA-N	50532576	CHEMBL4562189	Endothelin-1 receptor			 26							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532576&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9871561	440741158							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313991	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C24H23BrN6O6S/c1-34-19-9-5-6-10-20(19)37-21-22(31-38(32,33)30-13-17-7-3-2-4-8-17)28-16-29-23(21)35-11-12-36-24-26-14-18(25)15-27-24/h2-10,14-16,30H,11-13H2,1H3,(H,28,29,31)	LSQXFROVPNDBMN-UHFFFAOYSA-N	50395637	CHEMBL2165328	Endothelin-1 receptor			 6.9							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395637&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21979601	163344661		CHEMBL2165328				ZINC95557550	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313993	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)	JGCMEBMXRHSZKX-UHFFFAOYSA-N	50395626	ACT-064992::MACITENTAN	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395626&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16004692	163344650			DB08932			ZINC43202140	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313994	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(OC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H23BrN6O5S/c1-3-8-26-33(28,29)27-18-17(14-4-6-15(21)7-5-14)19(25-13-24-18)31-9-10-32-20-22-11-16(30-2)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	IDRSXRPOEONBKT-UHFFFAOYSA-N	50532594	CHEMBL4536769	Endothelin-1 receptor			 2.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532594&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041273	440741176							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313995	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C18H18BrClN6O4S/c1-2-25-31(27,28)26-16-15(12-3-5-14(20)6-4-12)17(24-11-23-16)29-7-8-30-18-21-9-13(19)10-22-18/h3-6,9-11,25H,2,7-8H2,1H3,(H,23,24,26)	KZUVKSRLOQJMKQ-UHFFFAOYSA-N	50532595	CHEMBL4449731	Endothelin-1 receptor			 2.2							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532595&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			90766557	440741177							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313996	CCNS(=O)(=O)Nc1ncnc(OCCOc2cc(OC)ccc2Cl)c1-c1ncc(SC)cn1	InChI=1S/C20H23ClN6O5S2/c1-4-26-34(28,29)27-19-17(18-22-10-14(33-3)11-23-18)20(25-12-24-19)32-8-7-31-16-9-13(30-2)5-6-15(16)21/h5-6,9-12,26H,4,7-8H2,1-3H3,(H,24,25,27)	NDGMTIKKHLLDIV-UHFFFAOYSA-N	50532596	CHEMBL4542394	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532596&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155551580	440741178							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313997	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1	InChI=1S/C23H21N5O5S/c1-15-8-9-19(25-14-15)34(29,30)28-22-20(33-18-7-5-4-6-17(18)31-2)23(32-3)27-21(26-22)16-10-12-24-13-11-16/h4-14H,1-3H3,(H,26,27,28)	YBWLTKFZAOSWSM-UHFFFAOYSA-N	50532577	Avosentan::RO 67-0565::RO-67-0565::Ro670565::SPP-301::SPP301	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532577&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9912992	440741159							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313998	COc1ccccc1Oc1c(OCCO)nc(nc1N(C)S(=O)(=O)c1ccc(cc1)C(C)(C)C)-c1ncccn1	InChI=1S/C28H31N5O6S/c1-28(2,3)19-11-13-20(14-12-19)40(35,36)33(4)26-23(39-22-10-7-6-9-21(22)37-5)27(38-18-17-34)32-25(31-26)24-29-15-8-16-30-24/h6-16,34H,17-18H2,1-5H3	MEVAKUYVUJUQRF-UHFFFAOYSA-N	50532600	CHEMBL4462548	Endothelin-1 receptor			>100000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532600&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			68169760	440741182							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51313999	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)cc(cc1OCCO)-c1ncccn1	InChI=1S/C29H31N3O6S/c1-29(2,3)21-10-12-22(13-11-21)39(34,35)32-23-18-20(28-30-14-7-15-31-28)19-26(37-17-16-33)27(23)38-25-9-6-5-8-24(25)36-4/h5-15,18-19,32-33H,16-17H2,1-4H3	MKIMHNDAGZDMKP-UHFFFAOYSA-N	50532601	CHEMBL4471434	Endothelin-1 receptor			 1300							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532601&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155535325	440741183							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314002	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C29H31N7O8S/c1-20-10-11-24(31-19-20)45(38,39)35-26-25(44-22-8-4-3-7-21(22)40-2)27(34-28(33-26)36-13-15-41-16-14-36)42-17-18-43-29(37)32-23-9-5-6-12-30-23/h3-12,19H,13-18H2,1-2H3,(H,30,32,37)(H,33,34,35)	OOJYMKAJOJBARX-UHFFFAOYSA-N	50290050	CHEMBL70385::Pyridin-2-yl-carbamic acid 2-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290050&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9939238	104131621		CHEMBL70385				ZINC03946721	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314003	COc1ccccc1Cc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C24H29N3O5S/c1-24(2,3)18-9-11-19(12-10-18)33(29,30)27-22-20(23(26-16-25-22)32-14-13-28)15-17-7-5-6-8-21(17)31-4/h5-12,16,28H,13-15H2,1-4H3,(H,25,26,27)	BXKRZXOFFXHLMM-UHFFFAOYSA-N	50532602	CHEMBL4584753	Endothelin-1 receptor			 2000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532602&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19735404	440741184							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314004	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1	InChI=1S/C23H21N5O5S/c1-15-8-9-19(25-14-15)34(29,30)28-22-20(33-18-7-5-4-6-17(18)31-2)23(32-3)27-21(26-22)16-10-12-24-13-11-16/h4-14H,1-3H3,(H,26,27,28)	YBWLTKFZAOSWSM-UHFFFAOYSA-N	50532577	Avosentan::RO 67-0565::RO-67-0565::Ro670565::SPP-301::SPP301	Endothelin-1 receptor			 1.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532577&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9912992	440741159							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314005	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 45							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314007	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)C)nc(nc1OCCO)C(F)(F)F	InChI=1S/C23H24F3N3O6S/c1-14(2)15-8-10-16(11-9-15)36(31,32)29-20-19(35-18-7-5-4-6-17(18)33-3)21(34-13-12-30)28-22(27-20)23(24,25)26/h4-11,14,30H,12-13H2,1-3H3,(H,27,28,29)	FKUFTGMFORIVAP-UHFFFAOYSA-N	50532576	CHEMBL4562189	Endothelin-1 receptor			 26							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532576&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9871561	440741158							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314008	COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C24H23BrN6O6S/c1-34-19-9-5-6-10-20(19)37-21-22(31-38(32,33)30-13-17-7-3-2-4-8-17)28-16-29-23(21)35-11-12-36-24-26-14-18(25)15-27-24/h2-10,14-16,30H,11-13H2,1H3,(H,28,29,31)	LSQXFROVPNDBMN-UHFFFAOYSA-N	50395637	CHEMBL2165328	Endothelin-1 receptor			 6.9							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395637&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21979601	163344661		CHEMBL2165328				ZINC95557550	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314010	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)	JGCMEBMXRHSZKX-UHFFFAOYSA-N	50395626	ACT-064992::MACITENTAN	Endothelin-1 receptor			 0.500000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395626&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			16004692	163344650			DB08932			ZINC43202140	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314011	CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(OC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C20H23BrN6O5S/c1-3-8-26-33(28,29)27-18-17(14-4-6-15(21)7-5-14)19(25-13-24-18)31-9-10-32-20-22-11-16(30-2)12-23-20/h4-7,11-13,26H,3,8-10H2,1-2H3,(H,24,25,27)	IDRSXRPOEONBKT-UHFFFAOYSA-N	50532594	CHEMBL4536769	Endothelin-1 receptor			 2.4							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532594&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041273	440741176							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314012	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Cl)cc1	InChI=1S/C18H18BrClN6O4S/c1-2-25-31(27,28)26-16-15(12-3-5-14(20)6-4-12)17(24-11-23-16)29-7-8-30-18-21-9-13(19)10-22-18/h3-6,9-11,25H,2,7-8H2,1H3,(H,23,24,26)	KZUVKSRLOQJMKQ-UHFFFAOYSA-N	50532595	CHEMBL4449731	Endothelin-1 receptor			 2.2							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532595&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			90766557	440741177							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314013	CCNS(=O)(=O)Nc1ncnc(OCCOc2cc(OC)ccc2Cl)c1-c1ncc(SC)cn1	InChI=1S/C20H23ClN6O5S2/c1-4-26-34(28,29)27-19-17(18-22-10-14(33-3)11-23-18)20(25-12-24-19)32-8-7-31-16-9-13(30-2)5-6-15(16)21/h5-6,9-12,26H,4,7-8H2,1-3H3,(H,24,25,27)	NDGMTIKKHLLDIV-UHFFFAOYSA-N	50532596	CHEMBL4542394	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532596&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155551580	440741178							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314014	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)c1ccccn1)N1CCOCC1	InChI=1S/C33H34N6O8S/c1-23(2)24-13-14-28(35-22-24)48(41,42)38-30-29(47-27-12-5-4-11-26(27)43-3)31(37-33(36-30)39-16-20-44-21-17-39)45-18-8-9-19-46-32(40)25-10-6-7-15-34-25/h4-7,10-15,22-23H,16-21H2,1-3H3,(H,36,37,38)	PBFKMRLPTUCFLU-UHFFFAOYSA-N	50532597	CHEMBL4448273	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532597&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155519384	440741179							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314015	COc1ccc(Cl)c(Oc2c(NS(C)(=O)=O)ncnc2OCCOc2ncc(cn2)S(C)(=O)=O)c1	InChI=1S/C19H20ClN5O8S2/c1-30-12-4-5-14(20)15(8-12)33-16-17(25-35(3,28)29)23-11-24-18(16)31-6-7-32-19-21-9-13(10-22-19)34(2,26)27/h4-5,8-11H,6-7H2,1-3H3,(H,23,24,25)	ZQMGLMDAJMDRHF-UHFFFAOYSA-N	50532598	CHEMBL4574034	Endothelin-1 receptor			 3.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532598&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155564169	440741180							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314016	CCCc1nc(SC2CCC(CC(O)=O)CC2)c(C(O)=O)n1Cc1cc2OCOc2cc1Cl	InChI=1S/C23H27ClN2O6S/c1-2-3-19-25-22(33-15-6-4-13(5-7-15)8-20(27)28)21(23(29)30)26(19)11-14-9-17-18(10-16(14)24)32-12-31-17/h9-10,13,15H,2-8,11-12H2,1H3,(H,27,28)(H,29,30)	GTTKJMGMAKZUDC-UHFFFAOYSA-N	50532603	CHEMBL4528664	Endothelin-1 receptor			 1.1							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532603&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9827093	440741185							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314017	COC([C@H](Oc1nc(C)cc(C)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1	OUJTZYPIHDYQMC-LJQANCHMSA-N	50146710	(S)-2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::AMBRISENTAN::CHEMBL1111::Letairis	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146710&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918493	104035299		CHEMBL1111		3951		ZINC00538627	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314018	CCCc1nc(C)ccc1O[C@@H](C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C27H30N2O6S/c1-5-6-22-23(13-7-18(4)28-22)35-26(20-10-14-24-25(15-20)34-16-33-24)27(30)29-36(31,32)21-11-8-19(9-12-21)17(2)3/h7-15,17,26H,5-6,16H2,1-4H3,(H,29,30)/t26-/m1/s1	KJNNBRVUQZDOET-AREMUKBSSA-N	50532599	CHEMBL4559129	Endothelin-1 receptor		 0.110000								ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532599&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9937336	440741181							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314027	COc1ccc(Cl)c(Oc2c(NS(=O)(=O)c3ccc(cc3)C(C)(C)C)nc(nc2OCCO)N2CCOCC2)c1	InChI=1S/C27H33ClN4O7S/c1-27(2,3)18-5-8-20(9-6-18)40(34,35)31-24-23(39-22-17-19(36-4)7-10-21(22)28)25(38-16-13-33)30-26(29-24)32-11-14-37-15-12-32/h5-10,17,33H,11-16H2,1-4H3,(H,29,30,31)	SNNWVBKDKWUMGJ-UHFFFAOYSA-N	50532585	CHEMBL4447261	Endothelin-1 receptor			 35							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532585&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155519245	440741167							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314029	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cn2)C(C)C)nc(nc1OCC#CCOC(=O)c1ccccn1)N1CCOCC1	InChI=1S/C33H34N6O8S/c1-23(2)24-13-14-28(35-22-24)48(41,42)38-30-29(47-27-12-5-4-11-26(27)43-3)31(37-33(36-30)39-16-20-44-21-17-39)45-18-8-9-19-46-32(40)25-10-6-7-15-34-25/h4-7,10-15,22-23H,16-21H2,1-3H3,(H,36,37,38)	PBFKMRLPTUCFLU-UHFFFAOYSA-N	50532597	CHEMBL4448273	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532597&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155519384	440741179							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314030	COc1ccc(Cl)c(Oc2c(NS(C)(=O)=O)ncnc2OCCOc2ncc(cn2)S(C)(=O)=O)c1	InChI=1S/C19H20ClN5O8S2/c1-30-12-4-5-14(20)15(8-12)33-16-17(25-35(3,28)29)23-11-24-18(16)31-6-7-32-19-21-9-13(10-22-19)34(2,26)27/h4-5,8-11H,6-7H2,1-3H3,(H,23,24,25)	ZQMGLMDAJMDRHF-UHFFFAOYSA-N	50532598	CHEMBL4574034	Endothelin-1 receptor			 3.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532598&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155564169	440741180							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314031	CCCc1nc(SC2CCC(CC(O)=O)CC2)c(C(O)=O)n1Cc1cc2OCOc2cc1Cl	InChI=1S/C23H27ClN2O6S/c1-2-3-19-25-22(33-15-6-4-13(5-7-15)8-20(27)28)21(23(29)30)26(19)11-14-9-17-18(10-16(14)24)32-12-31-17/h9-10,13,15H,2-8,11-12H2,1H3,(H,27,28)(H,29,30)	GTTKJMGMAKZUDC-UHFFFAOYSA-N	50532603	CHEMBL4528664	Endothelin-1 receptor			 1.1							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532603&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9827093	440741185							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314032	COC([C@H](Oc1nc(C)cc(C)n1)C(O)=O)(c1ccccc1)c1ccccc1	InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1	OUJTZYPIHDYQMC-LJQANCHMSA-N	50146710	(S)-2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid::AMBRISENTAN::CHEMBL1111::Letairis	Endothelin-1 receptor			 1.000000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146710&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			6918493	104035299		CHEMBL1111		3951		ZINC00538627	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314033	CCCc1nc(C)ccc1O[C@@H](C(=O)NS(=O)(=O)c1ccc(cc1)C(C)C)c1ccc2OCOc2c1	InChI=1S/C27H30N2O6S/c1-5-6-22-23(13-7-18(4)28-22)35-26(20-10-14-24-25(15-20)34-16-33-24)27(30)29-36(31,32)21-11-8-19(9-12-21)17(2)3/h7-15,17,26H,5-6,16H2,1-4H3,(H,29,30)/t26-/m1/s1	KJNNBRVUQZDOET-AREMUKBSSA-N	50532599	CHEMBL4559129	Endothelin-1 receptor		 0.110000								ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532599&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9937336	440741181							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314043	Cc1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C24H23BrN6O4S/c1-17-7-9-19(10-8-17)21-22(31-36(32,33)30-13-18-5-3-2-4-6-18)28-16-29-23(21)34-11-12-35-24-26-14-20(25)15-27-24/h2-10,14-16,30H,11-13H2,1H3,(H,28,29,31)	BIHSQJMJRJBBHK-UHFFFAOYSA-N	50395633	CHEMBL2165332	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395633&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462320	163344657		CHEMBL2165332				ZINC95556464	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314044	COc1ccccc1Oc1c(NS(=O)(=O)c2ccccc2)nc(nc1OCCO)-c1ncccn1	InChI=1S/C23H21N5O6S/c1-32-17-10-5-6-11-18(17)34-19-20(28-35(30,31)16-8-3-2-4-9-16)26-22(21-24-12-7-13-25-21)27-23(19)33-15-14-29/h2-13,29H,14-15H2,1H3,(H,26,27,28)	JRXMWZYIZDFZJX-UHFFFAOYSA-N	50532606	CHEMBL4572634	Endothelin-1 receptor			 1500							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532606&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			66875612	440741188							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314046	Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C23H27N3O4S/c1-16-5-7-17(8-6-16)20-21(24-15-25-22(20)30-14-13-27)26-31(28,29)19-11-9-18(10-12-19)23(2,3)4/h5-12,15,27H,13-14H2,1-4H3,(H,24,25,26)	ALQRUULAVXAWSN-UHFFFAOYSA-N	50105031	4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL324304	Endothelin-1 receptor			 1000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105031&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			12060119	104000828		CHEMBL324304				ZINC13864287	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314048	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C21H25BrN6O4S2/c1-3-4-9-27-34(29,30)28-19-18(15-5-7-16(22)8-6-15)20(26-14-25-19)31-10-11-32-21-23-12-17(33-2)13-24-21/h5-8,12-14,27H,3-4,9-11H2,1-2H3,(H,25,26,28)	XYKNJZNFEGDDIP-UHFFFAOYSA-N	50532604	CHEMBL4455360	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532604&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041284	440741186							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314049	COc1ccccc1Oc1c(NS(=O)(=O)c2ccccc2)nc(nc1OCCO)-c1ncccn1	InChI=1S/C23H21N5O6S/c1-32-17-10-5-6-11-18(17)34-19-20(28-35(30,31)16-8-3-2-4-9-16)26-22(21-24-12-7-13-25-21)27-23(19)33-15-14-29/h2-13,29H,14-15H2,1H3,(H,26,27,28)	JRXMWZYIZDFZJX-UHFFFAOYSA-N	50532606	CHEMBL4572634	Endothelin-1 receptor			 1500							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532606&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			66875612	440741188							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314051	Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C23H27N3O4S/c1-16-5-7-17(8-6-16)20-21(24-15-25-22(20)30-14-13-27)26-31(28,29)19-11-9-18(10-12-19)23(2,3)4/h5-12,15,27H,13-14H2,1-4H3,(H,24,25,26)	ALQRUULAVXAWSN-UHFFFAOYSA-N	50105031	4-tert-Butyl-N-[6-(2-hydroxy-ethoxy)-5-p-tolyl-pyrimidin-4-yl]-benzenesulfonamide::CHEMBL324304	Endothelin-1 receptor			 1000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105031&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			12060119	104000828		CHEMBL324304				ZINC13864287	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314053	Cc1ccc(cc1)-c1c(NS(=O)(=O)NCc2ccccc2)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C24H23BrN6O4S/c1-17-7-9-19(10-8-17)21-22(31-36(32,33)30-13-18-5-3-2-4-6-18)28-16-29-23(21)34-11-12-35-24-26-14-20(25)15-27-24/h2-10,14-16,30H,11-13H2,1H3,(H,28,29,31)	BIHSQJMJRJBBHK-UHFFFAOYSA-N	50395633	CHEMBL2165332	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395633&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			71462320	163344657		CHEMBL2165332				ZINC95556464	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314054	CCCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C21H25BrN6O4S2/c1-3-4-9-27-34(29,30)28-19-18(15-5-7-16(22)8-6-15)20(26-14-25-19)31-10-11-32-21-23-12-17(33-2)13-24-21/h5-8,12-14,27H,3-4,9-11H2,1-2H3,(H,25,26,28)	XYKNJZNFEGDDIP-UHFFFAOYSA-N	50532604	CHEMBL4455360	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532604&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			21041284	440741186							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314058	COc1cnc(OCCOc2nc(nc(NS(=O)(=O)NCc3ccccc3)c2-c2ccc(Cl)cc2)-c2ccncc2)nc1	InChI=1S/C29H26ClN7O5S/c1-40-24-18-32-29(33-19-24)42-16-15-41-28-25(21-7-9-23(30)10-8-21)27(35-26(36-28)22-11-13-31-14-12-22)37-43(38,39)34-17-20-5-3-2-4-6-20/h2-14,18-19,34H,15-17H2,1H3,(H,35,36,37)	AQDCZLZCKZWUCZ-UHFFFAOYSA-N	50532605	CHEMBL4572734	Endothelin-1 receptor			 2.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532605&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155563100	440741187							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314061	COc1ccccc1Oc1c(OCCO)nc(nc1N(C)S(=O)(=O)c1ccc(cc1)C(C)(C)C)-c1ncccn1	InChI=1S/C28H31N5O6S/c1-28(2,3)19-11-13-20(14-12-19)40(35,36)33(4)26-23(39-22-10-7-6-9-21(22)37-5)27(38-18-17-34)32-25(31-26)24-29-15-8-16-30-24/h6-16,34H,17-18H2,1-5H3	MEVAKUYVUJUQRF-UHFFFAOYSA-N	50532600	CHEMBL4462548	Endothelin-1 receptor			>100000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532600&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			68169760	440741182							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314062	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)cc(cc1OCCO)-c1ncccn1	InChI=1S/C29H31N3O6S/c1-29(2,3)21-10-12-22(13-11-21)39(34,35)32-23-18-20(28-30-14-7-15-31-28)19-26(37-17-16-33)27(23)38-25-9-6-5-8-24(25)36-4/h5-15,18-19,32-33H,16-17H2,1-4H3	MKIMHNDAGZDMKP-UHFFFAOYSA-N	50532601	CHEMBL4471434	Endothelin-1 receptor			 1300							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532601&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155535325	440741183							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314065	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OCCOC(=O)Nc1ccccn1)N1CCOCC1	InChI=1S/C29H31N7O8S/c1-20-10-11-24(31-19-20)45(38,39)35-26-25(44-22-8-4-3-7-21(22)40-2)27(34-28(33-26)36-13-15-41-16-14-36)42-17-18-43-29(37)32-23-9-5-6-12-30-23/h3-12,19H,13-18H2,1-2H3,(H,30,32,37)(H,33,34,35)	OOJYMKAJOJBARX-UHFFFAOYSA-N	50290050	CHEMBL70385::Pyridin-2-yl-carbamic acid 2-[5-(2-methoxy-phenoxy)-6-(5-methyl-pyridine-2-sulfonylamino)-2-morpholin-4-yl-pyrimidin-4-yloxy]-ethyl ester	Endothelin-1 receptor			 0.300000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290050&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9939238	104131621		CHEMBL70385				ZINC03946721	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314066	COc1ccccc1Cc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C24H29N3O5S/c1-24(2,3)18-9-11-19(12-10-18)33(29,30)27-22-20(23(26-16-25-22)32-14-13-28)15-17-7-5-6-8-21(17)31-4/h5-12,16,28H,13-15H2,1-4H3,(H,25,26,27)	BXKRZXOFFXHLMM-UHFFFAOYSA-N	50532602	CHEMBL4584753	Endothelin-1 receptor			 2000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532602&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19735404	440741184							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314067	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 80							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314069	COc1cnc(OCCOc2nc(nc(NS(=O)(=O)NCc3ccccc3)c2-c2ccc(Cl)cc2)-c2ccncc2)nc1	InChI=1S/C29H26ClN7O5S/c1-40-24-18-32-29(33-19-24)42-16-15-41-28-25(21-7-9-23(30)10-8-21)27(35-26(36-28)22-11-13-31-14-12-22)37-43(38,39)34-17-20-5-3-2-4-6-20/h2-14,18-19,34H,15-17H2,1H3,(H,35,36,37)	AQDCZLZCKZWUCZ-UHFFFAOYSA-N	50532605	CHEMBL4572734	Endothelin-1 receptor			 2.0							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532605&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155563100	440741187							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314070	COc1ccc(cc1)-c1nc(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c(Oc2ccccc2OC)c(OC[C@H](O)CO)n1	InChI=1S/C31H35N3O8S/c1-31(2,3)21-12-16-24(17-13-21)43(37,38)34-29-27(42-26-9-7-6-8-25(26)40-5)30(41-19-22(36)18-35)33-28(32-29)20-10-14-23(39-4)15-11-20/h6-17,22,35-36H,18-19H2,1-5H3,(H,32,33,34)/t22-/m1/s1	DRIHNVYRUGBDHI-JOCHJYFZSA-N	50532567	CHEMBL1628620::Ro-468443	Endothelin-1 receptor			 6800							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532567&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			5312146	440741149							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314072	CCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(SC)cn2)c1-c1ccc(Br)cc1	InChI=1S/C19H21BrN6O4S2/c1-3-25-32(27,28)26-17-16(13-4-6-14(20)7-5-13)18(24-12-23-17)29-8-9-30-19-21-10-15(31-2)11-22-19/h4-7,10-12,25H,3,8-9H2,1-2H3,(H,23,24,26)	GADXZXTXFHEOKH-UHFFFAOYSA-N	50532568	CHEMBL4565926	Endothelin-1 receptor			 0.700000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532568&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			58688005	440741150							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314073	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 80							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51314074	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)C(=O)Nc1ccccc1	InChI=1S/C30H32N4O7S/c1-30(2,3)20-14-16-22(17-15-20)42(37,38)34-26-25(41-24-13-9-8-12-23(24)39-4)29(40-19-18-35)33-27(32-26)28(36)31-21-10-6-5-7-11-21/h5-17,35H,18-19H2,1-4H3,(H,31,36)(H,32,33,34)	ODOHYBAWFJRUBM-UHFFFAOYSA-N	50532565	CHEMBL4447655	Endothelin-1 receptor			 13000							ChEMBL	10.1016/j.bmcl.2016.06.014	10.7270/Q26113SR	27321813			Boss, C; Bolli, MH; Gatfield, J	Actelion Pharmaceuticals Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532565&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44213959	440741147							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320729	[Na+].CCCC[C@H](NC(=O)[C@@H](Cc1cn(C(=O)OC)c2ccccc12)NC(=O)[C@@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C([O-])=O	InChI=1S/C34H51N5O7.Na/c1-8-9-16-25(31(42)43)35-29(40)26(18-23-20-38(33(45)46-7)28-17-11-10-15-24(23)28)36-30(41)27(19-34(4,5)6)37-32(44)39-21(2)13-12-14-22(39)3;/h10-11,15,17,20-22,25-27H,8-9,12-14,16,18-19H2,1-7H3,(H,35,40)(H,36,41)(H,37,44)(H,42,43);/q;+1/p-1/t21-,22+,25-,26+,27+;/m0./s1	QCVIFBRTTLMEOV-YPKROFLLSA-M	50534382	CHEMBL4568795	Endothelin-1 receptor			 1300							ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50534382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50534382&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			155560343	440742964							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320730	Cc1ccc(cc1)-c1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)CO)ncnc1OCCOc1ncc(Br)cn1	InChI=1S/C27H28BrN5O5S/c1-18-4-6-19(7-5-18)23-24(33-39(35,36)22-10-8-20(9-11-22)27(2,3)16-34)31-17-32-25(23)37-12-13-38-26-29-14-21(28)15-30-26/h4-11,14-15,17,34H,12-13,16H2,1-3H3,(H,31,32,33)	YAWNVAQKVARTGQ-UHFFFAOYSA-N	50105051	CHEMBL112624::N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)-ethoxy]-5-p-tolyl-pyrimidin-4-yl}-4-(2-hydroxy-1,1-dimethyl-ethyl)-benzenesulfonamide	Endothelin-1 receptor			 0.400000							ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105051&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9852318	104000848		CHEMBL112624				ZINC08576535	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320733	COc1ccc(CCOC([C@H](Oc2nc(C)cc(C)n2)C(O)=O)(c2ccccc2)c2ccccc2)cc1OC	InChI=1S/C31H32N2O6/c1-21-19-22(2)33-30(32-21)39-28(29(34)35)31(24-11-7-5-8-12-24,25-13-9-6-10-14-25)38-18-17-23-15-16-26(36-3)27(20-23)37-4/h5-16,19-20,28H,17-18H2,1-4H3,(H,34,35)/t28-/m1/s1	CLSJNXXMIVKULC-MUUNZHRXSA-N	50079424	(S)-3-[2-(3,4-Dimethoxy-phenyl)-ethoxy]-2-(4,6-dimethyl-pyrimidin-2-yloxy)-3,3-diphenyl-propionic acid::CHEMBL316735	Endothelin-1 receptor		 2.2								ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079424&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			9893800	103971676		CHEMBL316735					1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320735	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m1/s1	MOTJMGVDPWRKOC-QPVYNBJUSA-N	50051007	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::A-127722::CHEMBL9194	Endothelin-1 receptor		 0.034000								ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			159594	103948098		CHEMBL9194				ZINC03812144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320736	CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1	InChI=1S/C29H38N2O6/c1-4-6-14-30(15-7-5-2)26(32)18-31-17-23(21-10-13-24-25(16-21)37-19-36-24)27(29(33)34)28(31)20-8-11-22(35-3)12-9-20/h8-13,16,23,27-28H,4-7,14-15,17-19H2,1-3H3,(H,33,34)/t23-,27-,28+/m1/s1	MOTJMGVDPWRKOC-QPVYNBJUSA-N	50051007	(2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbamoylmethyl-2-(4-methoxy-phenyl)-pyrrolidine-3-carboxylic acid::A-127722::CHEMBL9194	Endothelin-1 receptor			 0.055000							ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051007&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			159594	103948098		CHEMBL9194				ZINC03812144	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320737	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 45							ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51320740	CN([C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1	InChI=1S/C36H35N3O4/c1-23-17-24(2)19-28(18-23)35(41)39(3)33(20-25-13-15-27(16-14-25)26-9-5-4-6-10-26)34(40)38-32(36(42)43)21-29-22-37-31-12-8-7-11-30(29)31/h4-19,22,32-33,37H,20-21H2,1-3H3,(H,38,40)(H,42,43)/t32-,33+/m0/s1	UZDORQWMYRRLQV-JHOUSYSJSA-N	50071433	(S)-2-{(R)-3-Biphenyl-4-yl-2-[(3,5-dimethyl-benzoyl)-methyl-amino]-propionylamino}-3-(1H-indol-3-yl)-propionic acid::CHEMBL72410	Endothelin-1 receptor			 94							ChEMBL	10.1021/acs.jmedchem.5b01781	10.7270/Q22N55RM	27266371			Aubert, JD; Juillerat-Jeanneret, L	Centre Hospitalier Universitaire Vaudois (CHUV)	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071433&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	D2U	6K1Q	5311192	103965186		CHEMBL72410		3887		ZINC01891205	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51356947	CN(C)CC\C=C\c1cccnc1	InChI=1S/C11H16N2/c1-13(2)9-4-3-6-11-7-5-8-12-10-11/h3,5-8,10H,4,9H2,1-2H3/b6-3+	ZZHZSKGOOLOJFA-ZZXKWVIFSA-N	50548708	CHEMBL4779424	Endothelin-1 receptor			>10000							ChEMBL	10.1016/j.bmc.2020.115820	10.7270/Q2WW7N96	33120080			Lin, SX; Curtis, MA; Sperry, J	University of Auckland	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50548708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50548708&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			20678881	461679048							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51520829	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ncccn1	InChI=1S/C27H29N5O6S/c1-27(2,3)18-10-12-19(13-11-18)39(34,35)32-23-22(38-21-9-6-5-8-20(21)36-4)26(37-17-16-33)31-25(30-23)24-28-14-7-15-29-24/h5-15,33H,16-17H2,1-4H3,(H,30,31,32)	GJPICJJJRGTNOD-UHFFFAOYSA-N	50061101	4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide::4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide::BOSENTAN::CHEMBL957::p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide	Endothelin-1 receptor			 80							ChEMBL		10.7270/Q21C223N	33314936			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061101&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	K86	5XPR	104865	103956688	51450	CHEMBL957	DB00559	3494		ZINC01538857	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51520826	OCCOc1ncnc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)c1-c1ccccc1	InChI=1S/C19H16F3N3O4S/c20-19(21,22)14-6-8-15(9-7-14)30(27,28)25-17-16(13-4-2-1-3-5-13)18(24-12-23-17)29-11-10-26/h1-9,12,26H,10-11H2,(H,23,24,25)	AYBGSDCWWQMMJY-UHFFFAOYSA-N	50612245	CHEMBL5272983	Endothelin-1 receptor			 18000							ChEMBL		10.7270/Q21C223N	33314936			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50612245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50612245&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			171348836	494501993							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51520827	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ncnc1OCCO	InChI=1S/C23H27N3O6S/c1-23(2,3)16-9-11-17(12-10-16)33(28,29)26-21-20(22(25-15-24-21)31-14-13-27)32-19-8-6-5-7-18(19)30-4/h5-12,15,27H,13-14H2,1-4H3,(H,24,25,26)	KPJXDJRWFUDSEA-UHFFFAOYSA-N	50532571	CHEMBL4525321	Endothelin-1 receptor			 1500							ChEMBL		10.7270/Q21C223N	33314936			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532571&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			10983585	440741153							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51520828	COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)nc(nc1OCCO)-c1ccccc1	InChI=1S/C29H31N3O6S/c1-29(2,3)21-14-16-22(17-15-21)39(34,35)32-27-25(38-24-13-9-8-12-23(24)36-4)28(37-19-18-33)31-26(30-27)20-10-6-5-7-11-20/h5-17,33H,18-19H2,1-4H3,(H,30,31,32)	HVRDENHNEUGHGW-UHFFFAOYSA-N	50532556	CHEMBL4438132	Endothelin-1 receptor			 800							ChEMBL		10.7270/Q21C223N	33314936			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50532556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50532556&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			19095644	440741138							1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2						
51540599	CN(C(=O)CC(C)(C)C)c1cc(ccc1-c1ccccc1S(=O)(=O)Nc1noc(C)c1C)-c1ncco1	InChI=1S/C27H30N4O5S/c1-17-18(2)36-29-25(17)30-37(33,34)23-10-8-7-9-21(23)20-12-11-19(26-28-13-14-35-26)15-22(20)31(6)24(32)16-27(3,4)5/h7-15H,16H2,1-6H3,(H,29,30)	AXFKGEZDVMCYEO-UHFFFAOYSA-N	50122676	CHEMBL274489::N-[2'-(4,5-Dimethyl-isoxazol-3-ylsulfamoyl)-4-oxazol-2-yl-biphenyl-2-yl]-3,3,N-trimethyl-butyramide	Endothelin-1 receptor	Homo sapiens	 10.0								ChEMBL	10.1016/j.ejmech.2022.114700	10.7270/Q20V8J54	36058089			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=49000502&target=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122676&enzyme=Endothelin-1+receptor&column=ki&startPg=0&Increment=50&submit=Search			44277840	104015316		CHEMBL274489				ZINC28768521	1	METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN	8HCQ,8XVL,8XVK,8XVJ	Endothelin-1 receptor	EDNRA_HUMAN	P25101	B2R723 B4E2V6 B7Z9G6 D3DP03 E7ER36 O43441 Q16432 Q16433 Q8TBH2