BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50320821 N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C27H27N5O5/c28-20-10-7-16(12-23(20)31-26(35)21(29)11-15-5-8-18(33)9-6-15)25(34)32-24(27(36)37)13-17-14-30-22-4-2-1-3-19(17)22/h1-10,12,14,21,24,30,33H,11,13,28-29H2,(H,31,35)(H,32,34)(H,36,37)/t21-,24-/m0/s1 QHWIGVDBCGDSQD-URXFXBBRSA-N 50077023 CHEMBL3416686 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077023&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734253 103969862 CHEMBL3416686 ZINC01663228 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320822 N[C@@H](CCc1ccc(OCc2ccccc2)cc1)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C42H41N5O5/c43-35-22-18-31(23-38(35)46-41(49)36(44)21-17-28-15-19-33(20-16-28)51-26-29-9-3-1-4-10-29)40(48)47-39(42(50)52-27-30-11-5-2-6-12-30)24-32-25-45-37-14-8-7-13-34(32)37/h1-16,18-20,22-23,25,36,39,45H,17,21,24,26-27,43-44H2,(H,46,49)(H,47,48)/t36-,39-/m0/s1 IUVPNCMZJKEEOP-VQIIKMDRSA-N 50077024 CHEMBL3416687 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077024&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734254 103969863 CHEMBL3416687 ZINC01491938 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320823 N[C@@H](CCc1ccc(O)cc1)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C28H29N5O5/c29-21-12-8-17(13-24(21)32-27(36)22(30)11-7-16-5-9-19(34)10-6-16)26(35)33-25(28(37)38)14-18-15-31-23-4-2-1-3-20(18)23/h1-6,8-10,12-13,15,22,25,31,34H,7,11,14,29-30H2,(H,32,36)(H,33,35)(H,37,38)/t22-,25-/m0/s1 LNNUPVVINPNLMQ-DHLKQENFSA-N 50077025 CHEMBL3416688 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077025&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734255 103969864 CHEMBL3416688 ZINC01685583 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320824 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 InChI=1S/C25H34N4O4/c1-4-5-11-20(27)24(31)28-21-14-18(12-13-19(21)26)23(30)29-22(16(2)3)25(32)33-15-17-9-7-6-8-10-17/h6-10,12-14,16,20,22H,4-5,11,15,26-27H2,1-3H3,(H,28,31)(H,29,30)/t20-,22-/m0/s1 WZXNZGDLXXYLLF-UNMCSNQZSA-N 50077026 CHEMBL3416689 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077026&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734256 103969865 CHEMBL3416689 ZINC05933280 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320825 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H28N4O4/c1-4-5-6-13(20)17(24)21-14-9-11(7-8-12(14)19)16(23)22-15(10(2)3)18(25)26/h7-10,13,15H,4-6,19-20H2,1-3H3,(H,21,24)(H,22,23)(H,25,26)/t13-,15-/m0/s1 PXCHMYHKPNRWSU-ZFWWWQNUSA-N 50077030 CHEMBL3416690 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077030&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734257 103969869 CHEMBL3416690 ZINC06535597 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320826 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OC InChI=1S/C23H30N4O5/c1-3-4-5-18(25)22(30)26-19-13-15(8-11-17(19)24)21(29)27-20(23(31)32-2)12-14-6-9-16(28)10-7-14/h6-11,13,18,20,28H,3-5,12,24-25H2,1-2H3,(H,26,30)(H,27,29)/t18-,20-/m0/s1 VKHXQOHDIBXTKK-ICSRJNTNSA-N 50077027 CHEMBL3416691 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 6400 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077027&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734258 103969866 CHEMBL3416691 ZINC06535303 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320827 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H35N5O4/c1-2-3-12-25(33)30(38)35-27-16-21(14-15-24(27)32)29(37)36-28(31(39)40-19-20-9-5-4-6-10-20)17-22-18-34-26-13-8-7-11-23(22)26/h4-11,13-16,18,25,28,34H,2-3,12,17,19,32-33H2,1H3,(H,35,38)(H,36,37)/t25-,28-/m0/s1 HNWIOZGMMTUVKP-LSYYVWMOSA-N 50077028 CHEMBL3416692 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1600 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077028&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734259 103969867 CHEMBL3416692 ZINC05933237 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320828 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C24H29N5O4/c1-2-3-7-18(26)23(31)28-20-11-14(9-10-17(20)25)22(30)29-21(24(32)33)12-15-13-27-19-8-5-4-6-16(15)19/h4-6,8-11,13,18,21,27H,2-3,7,12,25-26H2,1H3,(H,28,31)(H,29,30)(H,32,33)/t18-,21-/m0/s1 LWRHRPQZYICICQ-RXVVDRJESA-N 50077029 CHEMBL3416693 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3800 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077029&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734260 103969868 CHEMBL3416693 ZINC06535490 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320829 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)OC InChI=1S/C20H33N7O4/c1-3-4-6-14(22)18(29)27-16-11-12(8-9-13(16)21)17(28)26-15(19(30)31-2)7-5-10-25-20(23)24/h8-9,11,14-15H,3-7,10,21-22H2,1-2H3,(H,26,28)(H,27,29)(H4,23,24,25)/t14-,15-/m0/s1 OCOUSVQGBSKEJG-GJZGRUSLSA-N 50076970 CHEMBL3416694 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2500 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076970&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734261 313048493 CHEMBL3416694 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320830 CC(C)[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCCNC(N)=N)c1)C(O)=O InChI=1S/C18H29N7O4/c1-9(2)14(17(28)29)25-15(26)10-5-6-11(19)13(8-10)24-16(27)12(20)4-3-7-23-18(21)22/h5-6,8-9,12,14H,3-4,7,19-20H2,1-2H3,(H,24,27)(H,25,26)(H,28,29)(H4,21,22,23)/t12-,14-/m0/s1 XQKJTIQPTVHBOT-JSGCOSHPSA-N 50077031 CHEMBL3416695 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 5000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077031&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734262 103969870 CHEMBL3416695 ZINC05933240 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320831 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCCNC(N)=N)c1 InChI=1S/C23H31N7O5/c1-35-22(34)19(11-13-4-7-15(31)8-5-13)30-20(32)14-6-9-16(24)18(12-14)29-21(33)17(25)3-2-10-28-23(26)27/h4-9,12,17,19,31H,2-3,10-11,24-25H2,1H3,(H,29,33)(H,30,32)(H4,26,27,28)/t17-,19-/m0/s1 JECKMXQKZJERLG-HKUYNNGSSA-N 50076971 CHEMBL3416696 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 518 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076971&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 6PX 5K1V 118734263 313048494 CHEMBL3416696 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320832 N[C@@H](CCCNC(N)=N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O 50076972 CHEMBL3416697 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 589 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076972&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734264 313048495 CHEMBL3416697 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320833 COC(=O)c1ccc(NC(=O)[C@@H](N)CCc2ccccc2)c(N)c1 InChI=1S/C18H21N3O3/c1-24-18(23)13-8-10-16(15(20)11-13)21-17(22)14(19)9-7-12-5-3-2-4-6-12/h2-6,8,10-11,14H,7,9,19-20H2,1H3,(H,21,22)/t14-/m0/s1 OTQCWZVXWLSOOK-AWEZNQCLSA-N 50076973 CHEMBL3414595 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 58000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076973&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734265 313048496 CHEMBL3414595 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320834 COC(=O)c1ccc(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c(N)c1 InChI=1S/C17H19N3O4/c1-24-17(23)11-4-7-15(13(18)9-11)20-16(22)14(19)8-10-2-5-12(21)6-3-10/h2-7,9,14,21H,8,18-19H2,1H3,(H,20,22)/t14-/m0/s1 HHXPGGQSVXLNLE-AWEZNQCLSA-N 50077069 CHEMBL3416699 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 58000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077069&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734267 103969908 CHEMBL3416699 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320835 COC(=O)c1ccc(NC(=O)[C@@H](N)CC(C)C)c(N)c1 InChI=1S/C14H21N3O3/c1-8(2)6-11(16)13(18)17-12-5-4-9(7-10(12)15)14(19)20-3/h4-5,7-8,11H,6,15-16H2,1-3H3,(H,17,18)/t11-/m0/s1 HZNMRKXWWMZFAD-NSHDSACASA-N 50077098 CHEMBL3416700 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077098&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 110482493 103969937 CHEMBL3416700 ZINC03814418 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320836 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)OC InChI=1S/C14H21N3O3/c1-3-4-5-10(15)13(18)17-12-7-6-9(8-11(12)16)14(19)20-2/h6-8,10H,3-5,15-16H2,1-2H3,(H,17,18)/t10-/m0/s1 UHCKZKWYXZBNHT-JTQLQIEISA-N 50077103 CHEMBL3416701 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1100 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077103&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734268 103969942 CHEMBL3416701 ZINC28763852 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320837 COC(=O)c1ccc(NC(=O)[C@@H](N)CCCNC(N)=N)c(N)c1 InChI=1S/C14H22N6O3/c1-23-13(22)8-4-5-11(10(16)7-8)20-12(21)9(15)3-2-6-19-14(17)18/h4-5,7,9H,2-3,6,15-16H2,1H3,(H,20,21)(H4,17,18,19)/t9-/m0/s1 ZPJSMONGVMASNL-VIFPVBQESA-N 50077106 CHEMBL3416702 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2500 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077106&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734269 103969945 CHEMBL3416702 ZINC28763206 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320838 Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C25H24N4O3/c26-20-11-10-17(12-21(20)27)24(30)29-23(25(31)32-15-16-6-2-1-3-7-16)13-18-14-28-22-9-5-4-8-19(18)22/h1-12,14,23,28H,13,15,26-27H2,(H,29,30)/t23-/m0/s1 AFFIXHMSBIOQPX-QHCPKHFHSA-N 50077116 CHEMBL3416705 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077116&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734272 103969955 CHEMBL3416705 ZINC28765159 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320839 Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O 50076975 CHEMBL3416706 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1900 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076975&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734273 313048498 CHEMBL3416706 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320840 CC(C)[C@H](NC(=O)c1ccc(NC(=O)[C@@H](N)CCc2ccccc2)c(N)c1)C(=O)OCc1ccccc1 InChI=1S/C29H34N4O4/c1-19(2)26(29(36)37-18-21-11-7-4-8-12-21)33-27(34)22-14-16-25(24(31)17-22)32-28(35)23(30)15-13-20-9-5-3-6-10-20/h3-12,14,16-17,19,23,26H,13,15,18,30-31H2,1-2H3,(H,32,35)(H,33,34)/t23-,26-/m0/s1 UCUJMXWHUSZEFR-OZXSUGGESA-N 50077118 CHEMBL3416709 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077118&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734276 313073384 CHEMBL3416709 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320841 CC(C)[C@H](NC(=O)c1ccc(NC(=O)[C@@H](N)CCc2ccccc2)c(N)c1)C(O)=O InChI=1S/C22H28N4O4/c1-13(2)19(22(29)30)26-20(27)15-9-11-18(17(24)12-15)25-21(28)16(23)10-8-14-6-4-3-5-7-14/h3-7,9,11-13,16,19H,8,10,23-24H2,1-2H3,(H,25,28)(H,26,27)(H,29,30)/t16-,19-/m0/s1 FOWOQAULVRDYBB-LPHOPBHVSA-N 50077119 CHEMBL3416710 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077119&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734277 313073385 CHEMBL3416710 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320842 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(NC(=O)[C@@H](N)CCc2ccccc2)c(N)c1 InChI=1S/C27H30N4O5/c1-36-27(35)24(15-18-7-11-20(32)12-8-18)31-25(33)19-10-14-23(22(29)16-19)30-26(34)21(28)13-9-17-5-3-2-4-6-17/h2-8,10-12,14,16,21,24,32H,9,13,15,28-29H2,1H3,(H,30,34)(H,31,33)/t21-,24-/m0/s1 DQFIKNVMSSYTLN-URXFXBBRSA-N 50076977 CHEMBL3416711 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 5500 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076977&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734278 313048500 CHEMBL3416711 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320843 N[C@@H](CCc1ccccc1)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 50076978 CHEMBL3416712 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076978&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734279 313048501 CHEMBL3416712 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320844 COC(=O)[C@H](CCCNC(N)=N)NC(=O)c1ccc(NC(=O)[C@@H](N)CCc2ccccc2)c(N)c1 InChI=1S/C24H33N7O4/c1-35-23(34)20(8-5-13-29-24(27)28)31-21(32)16-10-12-19(18(26)14-16)30-22(33)17(25)11-9-15-6-3-2-4-7-15/h2-4,6-7,10,12,14,17,20H,5,8-9,11,13,25-26H2,1H3,(H,30,33)(H,31,32)(H4,27,28,29)/t17-,20-/m0/s1 RGOOEDGHYNFQAW-PXNSSMCTSA-N 50076979 CHEMBL3416713 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11800 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076979&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734280 313073378 CHEMBL3416713 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320845 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(NC(=O)[C@@H](N)Cc2ccc(OCc3ccccc3)cc2)c(N)c1 InChI=1S/C33H34N4O6/c1-42-33(41)30(18-22-7-12-25(38)13-8-22)37-31(39)24-11-16-29(27(34)19-24)36-32(40)28(35)17-21-9-14-26(15-10-21)43-20-23-5-3-2-4-6-23/h2-16,19,28,30,38H,17-18,20,34-35H2,1H3,(H,36,40)(H,37,39)/t28-,30-/m0/s1 AMTOLSBBIWXARE-JDXGNMNLSA-N 50077120 CHEMBL3416714 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 16000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077120&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734281 313073386 CHEMBL3416714 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320846 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c(N)c1 InChI=1S/C26H28N4O6/c1-36-26(35)23(13-16-4-9-19(32)10-5-16)30-24(33)17-6-11-22(20(27)14-17)29-25(34)21(28)12-15-2-7-18(31)8-3-15/h2-11,14,21,23,31-32H,12-13,27-28H2,1H3,(H,29,34)(H,30,33)/t21-,23-/m0/s1 MMHWDEYTWTZRBI-GMAHTHKFSA-N 50076980 CHEMBL3416715 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 15100 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076980&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734282 313048502 CHEMBL3416715 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320847 N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 50076981 CHEMBL3416716 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 20500 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076981&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734283 313048503 CHEMBL3416716 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320848 N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O 50076982 CHEMBL3416717 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4800 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076982&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734284 313048504 CHEMBL3416717 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320849 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c(N)c1 InChI=1S/C23H31N5O5/c1-33-23(32)20(4-2-3-11-24)28-21(30)15-7-10-19(17(25)13-15)27-22(31)18(26)12-14-5-8-16(29)9-6-14/h5-10,13,18,20,29H,2-4,11-12,24-26H2,1H3,(H,27,31)(H,28,30)/t18-,20-/m0/s1 CDXWFSXTZJQYJL-ICSRJNTNSA-N 50076983 CHEMBL3416718 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076983&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734285 313073379 CHEMBL3416718 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320850 N[C@@H](CCc1ccc(OCc2ccccc2)cc1)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 50077121 CHEMBL3416719 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 70000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077121&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734286 313073387 CHEMBL3416719 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320851 N[C@@H](CCc1ccc(O)cc1)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O 50076984 CHEMBL3416720 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 9400 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076984&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734287 313048505 CHEMBL3416720 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320852 CC(C)C[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 50077015 CHEMBL3416721 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 21000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077015&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734288 313073380 CHEMBL3416721 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320853 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 InChI=1S/C25H34N4O4/c1-4-5-11-19(26)24(31)28-21-13-12-18(14-20(21)27)23(30)29-22(16(2)3)25(32)33-15-17-9-7-6-8-10-17/h6-10,12-14,16,19,22H,4-5,11,15,26-27H2,1-3H3,(H,28,31)(H,29,30)/t19-,22-/m0/s1 MCENDTVOICFENC-UGKGYDQZSA-N 50077016 CHEMBL3416723 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 6200 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077016&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734290 313073381 CHEMBL3416723 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320854 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](C(C)C)C(O)=O InChI=1S/C18H28N4O4/c1-4-5-6-12(19)17(24)21-14-8-7-11(9-13(14)20)16(23)22-15(10(2)3)18(25)26/h7-10,12,15H,4-6,19-20H2,1-3H3,(H,21,24)(H,22,23)(H,25,26)/t12-,15-/m0/s1 JDDUXPOGNVSDKI-WFASDCNBSA-N 50077122 CHEMBL3416724 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 38000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077122&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734291 313073388 CHEMBL3416724 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320855 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OC InChI=1S/C23H30N4O5/c1-3-4-5-17(24)22(30)26-19-11-8-15(13-18(19)25)21(29)27-20(23(31)32-2)12-14-6-9-16(28)10-7-14/h6-11,13,17,20,28H,3-5,12,24-25H2,1-2H3,(H,26,30)(H,27,29)/t17-,20-/m0/s1 RXZHGXBRKJGXMY-PXNSSMCTSA-N 50077017 CHEMBL3416725 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 755 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077017&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734292 313073382 CHEMBL3416725 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320942 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 50077018 CHEMBL3416726 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 709 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077018&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734293 313073383 CHEMBL3416726 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320943 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C24H29N5O4/c1-2-3-7-17(25)23(31)28-20-10-9-14(11-18(20)26)22(30)29-21(24(32)33)12-15-13-27-19-8-5-4-6-16(15)19/h4-6,8-11,13,17,21,27H,2-3,7,12,25-26H2,1H3,(H,28,31)(H,29,30)(H,32,33)/t17-,21-/m0/s1 RJNOYRJGLPNURI-UWJYYQICSA-N 50077019 CHEMBL3416727 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 237 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077019&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734294 103969858 CHEMBL3416727 ZINC05933247 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320971 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](CCCCN)C(=O)OC InChI=1S/C20H33N5O4/c1-3-4-7-14(22)19(27)24-16-10-9-13(12-15(16)23)18(26)25-17(20(28)29-2)8-5-6-11-21/h9-10,12,14,17H,3-8,11,21-23H2,1-2H3,(H,24,27)(H,25,26)/t14-,17-/m0/s1 BADCYWFEGFJESY-YOEHRIQHSA-N 50077126 CHEMBL3416728 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 30600 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077126&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734295 313073392 CHEMBL3416728 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320972 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(NC(=O)[C@@H](N)CCCNC(N)=N)c(N)c1 InChI=1S/C23H31N7O5/c1-35-22(34)19(11-13-4-7-15(31)8-5-13)30-20(32)14-6-9-18(17(25)12-14)29-21(33)16(24)3-2-10-28-23(26)27/h4-9,12,16,19,31H,2-3,10-11,24-25H2,1H3,(H,29,33)(H,30,32)(H4,26,27,28)/t16-,19-/m0/s1 RQXULMRCYOSEPW-LPHOPBHVSA-N 50077020 CHEMBL3416729 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1400 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077020&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734296 103969859 CHEMBL3416729 ZINC05933150 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320973 N[C@@H](CCCNC(N)=N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C24H30N8O4/c25-16(5-3-9-29-24(27)28)22(34)31-19-8-7-13(10-17(19)26)21(33)32-20(23(35)36)11-14-12-30-18-6-2-1-4-15(14)18/h1-2,4,6-8,10,12,16,20,30H,3,5,9,11,25-26H2,(H,31,34)(H,32,33)(H,35,36)(H4,27,28,29)/t16-,20-/m0/s1 VAPOMUBVLCEHNL-JXFKEZNVSA-N 50077021 CHEMBL3416730 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1100 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077021&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734297 103969860 CHEMBL3416730 ZINC00007587 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320974 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(NC(=O)[C@@H](N)CCCNC(N)=N)c(N)c1 InChI=1S/C20H34N8O4/c1-32-19(31)16(6-2-3-9-21)28-17(29)12-7-8-15(14(23)11-12)27-18(30)13(22)5-4-10-26-20(24)25/h7-8,11,13,16H,2-6,9-10,21-23H2,1H3,(H,27,30)(H,28,29)(H4,24,25,26)/t13-,16-/m0/s1 MZDQTENBSHOAEA-BBRMVZONSA-N 50077127 CHEMBL3416731 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11800 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077127&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734298 313073393 CHEMBL3416731 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320975 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320593 COC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c1 InChI=1S/C17H19N3O4/c1-24-17(23)11-4-7-13(18)15(9-11)20-16(22)14(19)8-10-2-5-12(21)6-3-10/h2-7,9,14,21H,8,18-19H2,1H3,(H,20,22)/t14-/m0/s1 FYXDSEPUYWENOR-AWEZNQCLSA-N 50076745 CHEMBL3416566 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076745&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734160 313073374 CHEMBL3416566 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320594 N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1cc(ccc1N)C(O)=O InChI=1S/C16H17N3O4/c17-12-6-3-10(16(22)23)8-14(12)19-15(21)13(18)7-9-1-4-11(20)5-2-9/h1-6,8,13,20H,7,17-18H2,(H,19,21)(H,22,23)/t13-/m0/s1 KNGJUWNLZZBXNG-ZDUSSCGKSA-N 50076796 CHEMBL3416567 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3200 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076796&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734161 103969661 CHEMBL3416567 ZINC26012676 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320595 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)OC InChI=1S/C14H21N3O3/c1-3-4-5-11(16)13(18)17-12-8-9(14(19)20-2)6-7-10(12)15/h6-8,11H,3-5,15-16H2,1-2H3,(H,17,18)/t11-/m0/s1 QZUDGESOEVDJPR-NSHDSACASA-N 50076814 CHEMBL3416572 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 9800 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076814&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734165 103969679 CHEMBL3416572 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320596 COC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCCNC(N)=N)c1 InChI=1S/C14H22N6O3/c1-23-13(22)8-4-5-9(15)11(7-8)20-12(21)10(16)3-2-6-19-14(17)18/h4-5,7,10H,2-3,6,15-16H2,1H3,(H,20,21)(H4,17,18,19)/t10-/m0/s1 LUVNLXIAOJRTPZ-JTQLQIEISA-N 50076815 CHEMBL3416573 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3700 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076815&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734166 103969680 CHEMBL3416573 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320597 N[C@@H](CCCNC(N)=N)C(=O)Nc1cc(ccc1N)C(O)=O InChI=1S/C13H20N6O3/c14-8-4-3-7(12(21)22)6-10(8)19-11(20)9(15)2-1-5-18-13(16)17/h3-4,6,9H,1-2,5,14-15H2,(H,19,20)(H,21,22)(H4,16,17,18)/t9-/m0/s1 UEHRKPFCJFINDT-VIFPVBQESA-N 50076816 CHEMBL3416574 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076816&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734167 103969681 CHEMBL3416574 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320598 NCCCC[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccccc2)c1)C(O)=O InChI=1S/C22H29N5O4/c23-11-5-4-8-18(22(30)31)26-20(28)15-9-10-16(24)19(13-15)27-21(29)17(25)12-14-6-2-1-3-7-14/h1-3,6-7,9-10,13,17-18H,4-5,8,11-12,23-25H2,(H,26,28)(H,27,29)(H,30,31)/t17-,18-/m0/s1 DSAHOGXCYNYPGA-ROUUACIJSA-N 50076817 CHEMBL3416577 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2600 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076817&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734170 103969682 CHEMBL3416577 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320599 NCCCC[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c1)C(O)=O InChI=1S/C22H29N5O5/c23-10-2-1-3-18(22(31)32)26-20(29)14-6-9-16(24)19(12-14)27-21(30)17(25)11-13-4-7-15(28)8-5-13/h4-9,12,17-18,28H,1-3,10-11,23-25H2,(H,26,29)(H,27,30)(H,31,32)/t17-,18-/m0/s1 KUDYVACFLZITJM-ROUUACIJSA-N 50076850 CHEMBL3416578 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4500 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076850&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734171 103969715 CHEMBL3416578 ZINC15919388 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320600 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccc(O)cc2)c1 InChI=1S/C24H33N5O5/c1-34-24(33)20(4-2-3-13-25)28-22(31)16-8-12-18(26)21(14-16)29-23(32)19(27)11-7-15-5-9-17(30)10-6-15/h5-6,8-10,12,14,19-20,30H,2-4,7,11,13,25-27H2,1H3,(H,28,31)(H,29,32)/t19-,20-/m0/s1 MRRGURMAMRJVTJ-PMACEKPBSA-N 50076955 CHEMBL3416579 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4800 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076955&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734172 103969820 CHEMBL3416579 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320601 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccc(OCc3ccccc3)cc2)c1 InChI=1S/C31H39N5O5/c1-40-31(39)27(9-5-6-18-32)35-29(37)23-13-17-25(33)28(19-23)36-30(38)26(34)16-12-21-10-14-24(15-11-21)41-20-22-7-3-2-4-8-22/h2-4,7-8,10-11,13-15,17,19,26-27H,5-6,9,12,16,18,20,32-34H2,1H3,(H,35,37)(H,36,38)/t26-,27-/m0/s1 OOGZWXQNBBIFCX-SVBPBHIXSA-N 50076956 CHEMBL3416580 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 13000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076956&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734173 103969821 CHEMBL3416580 ZINC96255158 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320602 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CC(C)C)c1 InChI=1S/C20H33N5O4/c1-12(2)10-15(23)19(27)25-17-11-13(7-8-14(17)22)18(26)24-16(20(28)29-3)6-4-5-9-21/h7-8,11-12,15-16H,4-6,9-10,21-23H2,1-3H3,(H,24,26)(H,25,27)/t15-,16-/m0/s1 IWAUNRCIKSBKKY-HOTGVXAUSA-N 50076957 CHEMBL3416582 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 52000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076957&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734175 103969822 CHEMBL3416582 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320603 CC(C)C[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C19H31N5O4/c1-11(2)9-14(22)18(26)24-16-10-12(6-7-13(16)21)17(25)23-15(19(27)28)5-3-4-8-20/h6-7,10-11,14-15H,3-5,8-9,20-22H2,1-2H3,(H,23,25)(H,24,26)(H,27,28)/t14-,15-/m0/s1 QLZROVORQJBNKS-GJZGRUSLSA-N 50076958 CHEMBL3416583 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2100 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076958&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734176 103969823 CHEMBL3416583 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320604 CCCC[C@H](N)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](CCCCN)C(=O)OC InChI=1S/C20H33N5O4/c1-3-4-7-15(23)19(27)25-17-12-13(9-10-14(17)22)18(26)24-16(20(28)29-2)8-5-6-11-21/h9-10,12,15-16H,3-8,11,21-23H2,1-2H3,(H,24,26)(H,25,27)/t15-,16-/m0/s1 JVBSUICWFWXURK-HOTGVXAUSA-N 50076962 CHEMBL3416584 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8300 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076962&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734177 313073375 CHEMBL3416584 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320605 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCCNC(N)=N)c1 InChI=1S/C20H34N8O4/c1-32-19(31)15(6-2-3-9-21)27-17(29)12-7-8-13(22)16(11-12)28-18(30)14(23)5-4-10-26-20(24)25/h7-8,11,14-15H,2-6,9-10,21-23H2,1H3,(H,27,29)(H,28,30)(H4,24,25,26)/t14-,15-/m0/s1 HNAJEVYZXAMTTB-GJZGRUSLSA-N 50076964 CHEMBL3416585 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 17000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076964&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734178 313073376 CHEMBL3416585 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320606 CC(C)[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c1)C(=O)OCc1ccccc1 InChI=1S/C28H32N4O5/c1-17(2)25(28(36)37-16-19-6-4-3-5-7-19)32-26(34)20-10-13-22(29)24(15-20)31-27(35)23(30)14-18-8-11-21(33)12-9-18/h3-13,15,17,23,25,33H,14,16,29-30H2,1-2H3,(H,31,35)(H,32,34)/t23-,25-/m0/s1 BQXMBJJJTZTRFJ-ZCYQVOJMSA-N 50076965 CHEMBL3416586 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 50000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076965&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734179 313048489 CHEMBL3416586 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320607 CC(C)[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c1)C(O)=O InChI=1S/C21H26N4O5/c1-11(2)18(21(29)30)25-19(27)13-5-8-15(22)17(10-13)24-20(28)16(23)9-12-3-6-14(26)7-4-12/h3-8,10-11,16,18,26H,9,22-23H2,1-2H3,(H,24,28)(H,25,27)(H,29,30)/t16-,18-/m0/s1 IYCPZNUNKAAPIQ-WMZOPIPTSA-N 50076966 CHEMBL3416587 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076966&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734180 313048490 CHEMBL3416587 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320608 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c1 InChI=1S/C26H28N4O6/c1-36-26(35)23(13-16-4-9-19(32)10-5-16)30-24(33)17-6-11-20(27)22(14-17)29-25(34)21(28)12-15-2-7-18(31)8-3-15/h2-11,14,21,23,31-32H,12-13,27-28H2,1H3,(H,29,34)(H,30,33)/t21-,23-/m0/s1 MIESQMOIXPQTAY-GMAHTHKFSA-N 50076967 CHEMBL3416588 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 33000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076967&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734181 313073377 CHEMBL3416588 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320609 COC(=O)[C@@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)Cc2ccc(O)cc2)c1)[C@@H](C)O InChI=1S/C21H26N4O6/c1-11(26)18(21(30)31-2)25-19(28)13-5-8-15(22)17(10-13)24-20(29)16(23)9-12-3-6-14(27)7-4-12/h3-8,10-11,16,18,26-27H,9,22-23H2,1-2H3,(H,24,29)(H,25,28)/t11-,16+,18+/m1/s1 GOUYQAPKPTXGQY-VOZBZGINSA-N 50076968 CHEMBL3416589 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 39000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076968&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734182 313048491 CHEMBL3416589 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50320610 N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 50076969 CHEMBL3416685 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 40000 ChEMBL 10.1021/jm501867s 10.7270/Q2Z321B0 25635706 Papakyriakou, A; Zervoudi, E; Tsoukalidou, S; Mauvais, FX; Sfyroera, G; Mastellos, DC; van Endert, P; Theodorakis, EA; Vourloumis, D; Stratikos, E National Center for Scientific Research"Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076969&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734252 313048492 CHEMBL3416685 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517026 NC(CCc1ccc(O)cc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C19H24NO5P/c20-18(11-8-14-6-9-17(21)10-7-14)26(24,25)13-16(19(22)23)12-15-4-2-1-3-5-15/h1-7,9-10,16,18,21H,8,11-13,20H2,(H,22,23)(H,24,25) GEYBDNKUHPHUFQ-UHFFFAOYSA-N 50025044 CHEMBL3355103 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2180 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025044&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720632 313065057 CHEMBL3355103 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517027 NC(CCc1ccc(CO)cc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C20H26NO5P/c21-19(11-10-15-6-8-17(13-22)9-7-15)27(25,26)14-18(20(23)24)12-16-4-2-1-3-5-16/h1-9,18-19,22H,10-14,21H2,(H,23,24)(H,25,26) MRXHFZNHXQEPNB-UHFFFAOYSA-N 50025043 CHEMBL3355104 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 185 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025043&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720633 313065056 CHEMBL3355104 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517028 NC(CNC1CCCCC1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24) DDFITBNCTUGZCA-UHFFFAOYSA-N 50170882 CHEMBL3804856 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7940 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170882&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127048202 341104975 CHEMBL3804856 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517029 CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22) WQCVTAYXCVGUSK-UHFFFAOYSA-N 50170881 CHEMBL3805028 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 55300 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170881&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127048201 341104974 CHEMBL3805028 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517030 COc1ccc(CCNCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)cc1 InChI=1S/C21H29N2O5P/c1-28-19-9-7-16(8-10-19)11-12-23-14-20(22)29(26,27)15-18(21(24)25)13-17-5-3-2-4-6-17/h2-10,18,20,23H,11-15,22H2,1H3,(H,24,25)(H,26,27) XGTZMRSSJSALMZ-UHFFFAOYSA-N 50170884 CHEMBL3805495 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1300 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170884&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127051999 341104977 CHEMBL3805495 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517031 NC(CNC1CCCCCC1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C19H31N2O4P/c20-18(13-21-17-10-6-1-2-7-11-17)26(24,25)14-16(19(22)23)12-15-8-4-3-5-9-15/h3-5,8-9,16-18,21H,1-2,6-7,10-14,20H2,(H,22,23)(H,24,25) CCYMPAKREBKHRA-UHFFFAOYSA-N 50170883 CHEMBL3805118 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 9510 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170883&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127051701 341104976 CHEMBL3805118 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517036 CCCNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C15H25N2O4P/c1-2-8-17-10-14(16)22(20,21)11-13(15(18)19)9-12-6-4-3-5-7-12/h3-7,13-14,17H,2,8-11,16H2,1H3,(H,18,19)(H,20,21) OPXCWKOZEIXPRF-UHFFFAOYSA-N 50170880 CHEMBL3806187 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 5540 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170880&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127050430 341104973 CHEMBL3806187 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517038 NCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C12H19N2O4P/c13-7-11(14)19(17,18)8-10(12(15)16)6-9-4-2-1-3-5-9/h1-5,10-11H,6-8,13-14H2,(H,15,16)(H,17,18) JWNQCURWOLEWRL-UHFFFAOYSA-N 50170879 CHEMBL3805472 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3020 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170879&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127049497 341104972 CHEMBL3805472 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517041 CC(C)C[C@@H](N)P(O)(O)=O InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1 HGCAUCAWEADMPM-YFKPBYRVSA-N 50190114 CHEMBL288165 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190114&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 2WW 4PVB 1551321 346535319 CHEMBL288165 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50517035 NC(CN1CCOCC1)P(O)(O)=O InChI=1S/C6H15N2O4P/c7-6(13(9,10)11)5-8-1-3-12-4-2-8/h6H,1-5,7H2,(H2,9,10,11) MYBQWHIHPBOCKG-UHFFFAOYSA-N 50170901 CHEMBL3805587 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170901&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127048200 104057257 CHEMBL3805587 ZINC13648575 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516644 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(N)=O InChI=1S/C16H27N2O3P/c1-12(2)10-14(16(18)19)11-22(20,21)15(17)9-8-13-6-4-3-5-7-13/h3-7,12,14-15H,8-11,17H2,1-2H3,(H2,18,19)(H,20,21)/t14-,15-/m1/s1 BEWRVZZHISITDQ-HUUCEWRRSA-N 50190107 CHEMBL3827468 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 550 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190107&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127043855 346535312 CHEMBL3827468 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516645 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516646 NC(CN1CCCCC1)P(O)(O)=O InChI=1S/C7H17N2O3P/c8-7(13(10,11)12)6-9-4-2-1-3-5-9/h7H,1-6,8H2,(H2,10,11,12) ZUQPVFADDWEXEY-UHFFFAOYSA-N 50170893 CHEMBL3804843 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 622 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170893&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127049157 104057249 CHEMBL3804843 ZINC36271440 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516647 COc1ccc(CCNCC(N)P(O)(O)=O)cc1 InChI=1S/C11H19N2O4P/c1-17-10-4-2-9(3-5-10)6-7-13-8-11(12)18(14,15)16/h2-5,11,13H,6-8,12H2,1H3,(H2,14,15,16) HFIVLLBFACNAFN-UHFFFAOYSA-N 50170878 CHEMBL3806197 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1680 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170878&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127052870 341104971 CHEMBL3806197 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516648 NCc1ccc(CNCC(N)P(O)(O)=O)cc1 InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16) PRJZGAQJDFCWMW-UHFFFAOYSA-N 50170877 CHEMBL3804956 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3470 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170877&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127052612 341104970 CHEMBL3804956 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516649 COc1ccc(CNCC(N)P(O)(O)=O)cc1 InChI=1S/C10H17N2O4P/c1-16-9-4-2-8(3-5-9)6-12-7-10(11)17(13,14)15/h2-5,10,12H,6-7,11H2,1H3,(H2,13,14,15) VWNDRFCIOOHIKL-UHFFFAOYSA-N 50170876 CHEMBL3805817 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8230 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170876&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127051959 341104969 CHEMBL3805817 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516650 NC(CNCc1ccc(N)cc1)P(O)(O)=O InChI=1S/C9H16N3O3P/c10-8-3-1-7(2-4-8)5-12-6-9(11)16(13,14)15/h1-4,9,12H,5-6,10-11H2,(H2,13,14,15) ZMOXZXZELGWRBL-UHFFFAOYSA-N 50170875 CHEMBL3805288 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 24900 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170875&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127051304 341104968 CHEMBL3805288 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516651 NC(CNCCc1ccccc1)P(O)(O)=O InChI=1S/C10H17N2O3P/c11-10(16(13,14)15)8-12-7-6-9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2,(H2,13,14,15) DRHNMARMYWMTKK-UHFFFAOYSA-N 50170874 CHEMBL3805544 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1020 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170874&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127050130 341104967 CHEMBL3805544 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516652 CC(C)(C)c1ccc(CNCC(N)P(O)(O)=O)cc1 InChI=1S/C13H23N2O3P/c1-13(2,3)11-6-4-10(5-7-11)8-15-9-12(14)19(16,17)18/h4-7,12,15H,8-9,14H2,1-3H3,(H2,16,17,18) QNKKKMQBKFURKO-UHFFFAOYSA-N 50170873 CHEMBL3805193 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11500 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170873&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127050745 341104966 CHEMBL3805193 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516653 NC(CNCc1ccccc1)P(O)(O)=O InChI=1S/C9H15N2O3P/c10-9(15(12,13)14)7-11-6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2,(H2,12,13,14) TYSJLDXCWVWYDI-UHFFFAOYSA-N 50170891 CHEMBL3805986 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 106000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170891&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 5HR 5DYF 13509139 341104983 CHEMBL3805986 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516654 NC(CNCCN1CCNCC1)P(O)(O)=O InChI=1S/C8H21N4O3P/c9-8(16(13,14)15)7-11-3-6-12-4-1-10-2-5-12/h8,10-11H,1-7,9H2,(H2,13,14,15) URXWEUUHBUFBRN-UHFFFAOYSA-N 50170871 CHEMBL3806230 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7700 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170871&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127050433 341104965 CHEMBL3806230 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516655 NC(CNCC1CCNCC1)P(O)(O)=O InChI=1S/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14) URLVWQSQTPWELN-UHFFFAOYSA-N 50170894 CHEMBL3805338 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1420 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170894&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127053163 104057250 CHEMBL3805338 ZINC36271533 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516656 NC(CNC1CCCCC1N)P(O)(O)=O InChI=1S/C8H20N3O3P/c9-6-3-1-2-4-7(6)11-5-8(10)15(12,13)14/h6-8,11H,1-5,9-10H2,(H2,12,13,14) JQPUWMCHQHVQGE-UHFFFAOYSA-N 50170896 CHEMBL3805251 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 10300 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170896&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127049196 104057252 CHEMBL3805251 ZINC28461456 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516657 NC(CNC1CCCCCC1)P(O)(O)=O InChI=1S/C9H21N2O3P/c10-9(15(12,13)14)7-11-8-5-3-1-2-4-6-8/h8-9,11H,1-7,10H2,(H2,12,13,14) PTRBOGHDUIAFRB-UHFFFAOYSA-N 50170897 CHEMBL3805573 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 10600 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170897&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127049824 104057253 CHEMBL3805573 ZINC28465694 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516658 NC(CNC1CCCCC1)P(O)(O)=O InChI=1S/C8H19N2O3P/c9-8(14(11,12)13)6-10-7-4-2-1-3-5-7/h7-8,10H,1-6,9H2,(H2,11,12,13) FCNVXOHFLIBILW-UHFFFAOYSA-N 50170890 CHEMBL3806072 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8190 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170890&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 37E 4QPE 53792079 341104982 CHEMBL3806072 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516660 CCCCCCNCC(N)P(O)(O)=O InChI=1S/C8H21N2O3P/c1-2-3-4-5-6-10-7-8(9)14(11,12)13/h8,10H,2-7,9H2,1H3,(H2,11,12,13) JREUTUCRLBCPNH-UHFFFAOYSA-N 50170900 CHEMBL3806247 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 632 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170900&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127052273 104057256 CHEMBL3806247 ZINC28459840 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516666 NCC(N)P(O)(O)=O InChI=1S/C2H9N2O3P/c3-1-2(4)8(5,6)7/h2H,1,3-4H2,(H2,5,6,7) CCYLOQJVEOHSGI-UHFFFAOYSA-N 50170885 CHEMBL3806121 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 16900 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170885&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 281242 341104978 CHEMBL3806121 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516667 NCc1cccc(CC(CP(O)(=O)C(N)CCc2cccnc2)C(O)=O)c1 InChI=1S/C19H26N3O4P/c20-11-16-4-1-3-15(9-16)10-17(19(23)24)13-27(25,26)18(21)7-6-14-5-2-8-22-12-14/h1-5,8-9,12,17-18H,6-7,10-11,13,20-21H2,(H,23,24)(H,25,26) ILPPMAMWVKWZLK-UHFFFAOYSA-N 50190108 CHEMBL3827529 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190108&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127044996 346535313 CHEMBL3827529 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516668 NCc1ccc(CC(CP(O)(=O)C(N)CCc2ccncc2)C(O)=O)cc1 InChI=1S/C19H26N3O4P/c20-12-16-3-1-15(2-4-16)11-17(19(23)24)13-27(25,26)18(21)6-5-14-7-9-22-10-8-14/h1-4,7-10,17-18H,5-6,11-13,20-21H2,(H,23,24)(H,25,26) GJIDXMBXAKRGEE-UHFFFAOYSA-N 50190113 CHEMBL3828715 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 65200 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190113&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127044995 346535318 CHEMBL3828715 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516680 NC(CCc1cccnc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C18H23N2O4P/c19-17(9-8-15-7-4-10-20-12-15)25(23,24)13-16(18(21)22)11-14-5-2-1-3-6-14/h1-7,10,12,16-17H,8-9,11,13,19H2,(H,21,22)(H,23,24) LWRKOPLMYMXZKW-UHFFFAOYSA-N 50025042 CHEMBL3355105 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 205 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025042&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 379 4QIR 118720634 313065055 CHEMBL3355105 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516682 CC(NCC(N)P(O)(O)=O)c1ccccc1 InChI=1S/C10H17N2O3P/c1-8(9-5-3-2-4-6-9)12-7-10(11)16(13,14)15/h2-6,8,10,12H,7,11H2,1H3,(H2,13,14,15) LRYVOWVFITYCIO-UHFFFAOYSA-N 50170892 CHEMBL3804861 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170892&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127049491 341104984 CHEMBL3804861 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516683 NC(CCc1ccncc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C18H23N2O4P/c19-17(7-6-14-8-10-20-11-9-14)25(23,24)13-16(18(21)22)12-15-4-2-1-3-5-15/h1-5,8-11,16-17H,6-7,12-13,19H2,(H,21,22)(H,23,24) SXZZIOOVCGCZRP-UHFFFAOYSA-N 50025041 CHEMBL3355106 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 241 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025041&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720635 103935003 CHEMBL3355106 ZINC29327451 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516690 NC(CCc1ccccc1)P(O)(O)=O InChI=1S/C9H14NO3P/c10-9(14(11,12)13)7-6-8-4-2-1-3-5-8/h1-5,9H,6-7,10H2,(H2,11,12,13) NAPHUBPIUWHFCT-UHFFFAOYSA-N 50316049 1-amino-3-phenylpropylphosphonic acid::CHEMBL1090914 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316049&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 2X0 6MGQ,5AB0,4PW4,4Z7I 11127644 104150410 CHEMBL1090914 ZINC13525055 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516691 NC(CNCC1CCCO1)P(O)(O)=O InChI=1S/C7H17N2O4P/c8-7(14(10,11)12)5-9-4-6-2-1-3-13-6/h6-7,9H,1-5,8H2,(H2,10,11,12) XELVYRKYZFBRMR-UHFFFAOYSA-N 50170895 CHEMBL3805487 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170895&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127048834 104057251 CHEMBL3805487 ZINC36271462 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516705 CC(C)C[C@H](N)P(O)(O)=O InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1 HGCAUCAWEADMPM-RXMQYKEDSA-N 50190109 Leucine Phosphonic acid Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190109&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search PLE 445715 346535314 DB02386 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516708 NCCNCC(N)P(O)(O)=O InChI=1S/C4H14N3O3P/c5-1-2-7-3-4(6)11(8,9)10/h4,7H,1-3,5-6H2,(H2,8,9,10) YZZVYJAKRZZYBF-UHFFFAOYSA-N 50170899 CHEMBL3806100 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170899&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 87495845 104057255 CHEMBL3806100 ZINC28468401 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516686 Cc1cc(C)cc(CC(CP(O)(=O)C(N)CCc2ccccc2)C(O)=O)c1 InChI=1S/C21H28NO4P/c1-15-10-16(2)12-18(11-15)13-19(21(23)24)14-27(25,26)20(22)9-8-17-6-4-3-5-7-17/h3-7,10-12,19-20H,8-9,13-14,22H2,1-2H3,(H,23,24)(H,25,26) XTCAOJQUSFRSJC-UHFFFAOYSA-N 50025049 CHEMBL3355107 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025049&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720636 313065061 CHEMBL3355107 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516687 NCc1cccc(CC(CP(O)(=O)C(N)CCc2ccccc2)C(O)=O)c1 InChI=1S/C20H27N2O4P/c21-13-17-8-4-7-16(11-17)12-18(20(23)24)14-27(25,26)19(22)10-9-15-5-2-1-3-6-15/h1-8,11,18-19H,9-10,12-14,21-22H2,(H,23,24)(H,25,26) OGZYJUYHRXGJNP-UHFFFAOYSA-N 50025050 CHEMBL3355108 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025050&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 3DZ 4QUO 118720637 313065062 CHEMBL3355108 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516688 NCc1ccc(CC(CP(O)(=O)C(N)CCc2ccccc2)C(O)=O)cc1 InChI=1S/C20H27N2O4P/c21-13-17-8-6-16(7-9-17)12-18(20(23)24)14-27(25,26)19(22)11-10-15-4-2-1-3-5-15/h1-9,18-19H,10-14,21-22H2,(H,23,24)(H,25,26) XZFPYKBNMOQQLL-UHFFFAOYSA-N 50025066 CHEMBL3355109 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025066&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 32Q 4QHP 118720638 103935018 CHEMBL3355109 ZINC03870874 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516786 CN(C)CCNCC(N)P(O)(O)=O InChI=1S/C6H18N3O3P/c1-9(2)4-3-8-5-6(7)13(10,11)12/h6,8H,3-5,7H2,1-2H3,(H2,10,11,12) ARYLOGLNSUZRSA-UHFFFAOYSA-N 50170898 CHEMBL3805964 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170898&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 127049492 104057254 CHEMBL3805964 ZINC36271491 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516815 NC(CCc1ccccc1)P(O)(=O)CC(Cc1ccc(O)cc1)C(O)=O InChI=1S/C19H24NO5P/c20-18(11-8-14-4-2-1-3-5-14)26(24,25)13-16(19(22)23)12-15-6-9-17(21)10-7-15/h1-7,9-10,16,18,21H,8,11-13,20H2,(H,22,23)(H,24,25) STVSJGZHUJJREA-UHFFFAOYSA-N 50190112 CHEMBL88808 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1040 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190112&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 10970861 346535317 CHEMBL88808 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516817 CNCC(N)P(O)(O)=O InChI=1S/C3H11N2O3P/c1-5-2-3(4)9(6,7)8/h3,5H,2,4H2,1H3,(H2,6,7,8) ZQVMIWFDBJSLTM-UHFFFAOYSA-N 50170886 CHEMBL3804959 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170886&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 15849848 341104979 CHEMBL3804959 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516818 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C19H24NO4P/c20-18(12-11-15-7-3-1-4-8-15)25(23,24)14-17(19(21)22)13-16-9-5-2-6-10-16/h1-10,17-18H,11-14,20H2,(H,21,22)(H,23,24)/t17-,18-/m1/s1 QELOIXSGJMIHBZ-QZTJIDSGSA-N 50190110 CHEMBL254284 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1030 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190110&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 37B 4QME 44447089 346535315 CHEMBL254284 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516819 CCCNCC(N)P(O)(O)=O InChI=1S/C5H15N2O3P/c1-2-3-7-4-5(6)11(8,9)10/h5,7H,2-4,6H2,1H3,(H2,8,9,10) WQIIZRIJSQZVGR-UHFFFAOYSA-N 50170888 CHEMBL3805557 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >250000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170888&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 86140993 341104980 CHEMBL3805557 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516839 NC(CCc1ccccc1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C19H24NO4P/c20-18(12-11-15-7-3-1-4-8-15)25(23,24)14-17(19(21)22)13-16-9-5-2-6-10-16/h1-10,17-18H,11-14,20H2,(H,21,22)(H,23,24) QELOIXSGJMIHBZ-UHFFFAOYSA-N 50190111 CHEMBL327844 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 350 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50190111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50190111&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 37B 3EBI,3KR5 11142955 346535316 CHEMBL327844 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516840 N[C@@H](CCc1ccccc1)P(O)(O)=O InChI=1S/C9H14NO3P/c10-9(14(11,12)13)7-6-8-4-2-1-3-5-8/h1-5,9H,6-7,10H2,(H2,11,12,13)/t9-/m1/s1 NAPHUBPIUWHFCT-SECBINFHSA-N 50025048 CHEMBL3355099 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 47000 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025048&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 2X0 6MGQ,5AB0,4PW4,4Z7I 74766022 103935004 CHEMBL3355099 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516841 Cc1cc(C)cc(CCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)c1 InChI=1S/C21H28NO4P/c1-15-10-16(2)12-18(11-15)8-9-20(22)27(25,26)14-19(21(23)24)13-17-6-4-3-5-7-17/h3-7,10-12,19-20H,8-9,13-14,22H2,1-2H3,(H,23,24)(H,25,26) WSOAEHRSZIUDNJ-UHFFFAOYSA-N 50025047 CHEMBL3355100 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7670 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025047&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720629 313065060 CHEMBL3355100 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516843 NC(CCc1ccc(cc1)[N+]([O-])=O)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C19H23N2O6P/c20-18(11-8-14-6-9-17(10-7-14)21(24)25)28(26,27)13-16(19(22)23)12-15-4-2-1-3-5-15/h1-7,9-10,16,18H,8,11-13,20H2,(H,22,23)(H,26,27) YSYQXQQIKOEBNN-UHFFFAOYSA-N 50025046 CHEMBL3355101 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 152 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025046&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720630 313065059 CHEMBL3355101 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50516844 NC(CCc1cccc(O)c1)P(O)(=O)CC(Cc1ccccc1)C(O)=O InChI=1S/C19H24NO5P/c20-18(10-9-15-7-4-8-17(21)12-15)26(24,25)13-16(19(22)23)11-14-5-2-1-3-6-14/h1-8,12,16,18,21H,9-11,13,20H2,(H,22,23)(H,24,25) FYGJSIIQNXLTQW-UHFFFAOYSA-N 50025045 CHEMBL3355102 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4570 ChEMBL 10.1016/j.bmcl.2016.06.062 10.7270/Q2TT4SW1 27390066 Weglarz-Tomczak, E; Vassiliou, S; Mucha, A Wroclaw University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025045&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118720631 313065058 CHEMBL3355102 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074382 N[C@@H](CCc1ccccc1)C(=O)Nc1cc(ccc1N)C(O)=O InChI=1S/C17H19N3O3/c18-13-9-7-12(17(22)23)10-15(13)20-16(21)14(19)8-6-11-4-2-1-3-5-11/h1-5,7,9-10,14H,6,8,18-19H2,(H,20,21)(H,22,23)/t14-/m0/s1 WIMZOEBIGFNYPP-AWEZNQCLSA-N 50439348 CHEMBL2420387 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439348&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817966 175451665 CHEMBL2420387 ZINC96283132 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074383 COC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccccc2)c1 InChI=1S/C18H21N3O3/c1-24-18(23)13-8-10-14(19)16(11-13)21-17(22)15(20)9-7-12-5-3-2-4-6-12/h2-6,8,10-11,15H,7,9,19-20H2,1H3,(H,21,22)/t15-/m0/s1 SJIIIAUNZWYGEE-HNNXBMFYSA-N 50439349 CHEMBL2420386 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439349&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817965 175451666 CHEMBL2420386 ZINC96283133 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074384 N[C@@H](CCc1ccccc1)C(=O)Nc1cc(ccc1N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C35H35N5O4/c36-28-18-16-25(19-31(28)39-34(42)29(37)17-15-23-9-3-1-4-10-23)33(41)40-32(35(43)44-22-24-11-5-2-6-12-24)20-26-21-38-30-14-8-7-13-27(26)30/h1-14,16,18-19,21,29,32,38H,15,17,20,22,36-37H2,(H,39,42)(H,40,41)/t29-,32-/m0/s1 CEQZWGIVPRHZJH-NYDCQLBNSA-N 50439350 CHEMBL2420385 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 23900 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439350&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817964 175451667 CHEMBL2420385 ZINC96283134 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074385 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccccc2)c1 InChI=1S/C27H30N4O5/c1-36-27(35)24(15-18-7-11-20(32)12-8-18)31-25(33)19-10-14-21(28)23(16-19)30-26(34)22(29)13-9-17-5-3-2-4-6-17/h2-8,10-12,14,16,22,24,32H,9,13,15,28-29H2,1H3,(H,30,34)(H,31,33)/t22-,24-/m0/s1 ASZXUJWASJMAAI-UPVQGACJSA-N 50439351 CHEMBL2420384 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439351&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817963 175451668 CHEMBL2420384 ZINC96283135 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074386 NCCCC[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccccc2)c1)C(O)=O InChI=1S/C23H31N5O4/c24-13-5-4-8-19(23(31)32)27-21(29)16-10-12-17(25)20(14-16)28-22(30)18(26)11-9-15-6-2-1-3-7-15/h1-3,6-7,10,12,14,18-19H,4-5,8-9,11,13,24-26H2,(H,27,29)(H,28,30)(H,31,32)/t18-,19-/m0/s1 XPUCDWKMNQBXIH-OALUTQOASA-N 50439353 CHEMBL2420382 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8900 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439353&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817810 175451670 CHEMBL2420382 ZINC96283137 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074387 COC(=O)[C@H](CCCCN)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccccc2)c1 InChI=1S/C24H33N5O4/c1-33-24(32)20(9-5-6-14-25)28-22(30)17-11-13-18(26)21(15-17)29-23(31)19(27)12-10-16-7-3-2-4-8-16/h2-4,7-8,11,13,15,19-20H,5-6,9-10,12,14,25-27H2,1H3,(H,28,30)(H,29,31)/t19-,20-/m0/s1 PLKKJOBNGCNHOY-PMACEKPBSA-N 50439354 CHEMBL2420381 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 24900 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439354&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817809 175451671 CHEMBL2420381 ZINC96283138 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51074388 CC(C)[C@H](NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCc2ccccc2)c1)C(=O)OCc1ccccc1 InChI=1S/C29H34N4O4/c1-19(2)26(29(36)37-18-21-11-7-4-8-12-21)33-27(34)22-14-16-23(30)25(17-22)32-28(35)24(31)15-13-20-9-5-3-6-10-20/h3-12,14,16-17,19,24,26H,13,15,18,30-31H2,1-2H3,(H,32,35)(H,33,34)/t24-,26-/m0/s1 UKJHTSLJHWRDGS-AHWVRZQESA-N 50439357 CHEMBL2420378 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11500 ChEMBL 10.1016/j.bmcl.2013.07.024 10.7270/Q2J38V00 23916253 Papakyriakou, A; Zervoudi, E; Theodorakis, EA; Saveanu, L; Stratikos, E; Vourloumis, D University of California San Diego http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439357&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 71817806 175451674 CHEMBL2420378 ZINC96283141 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50555796 ONC(=O)C(Cc1ccc(F)cc1)C(=O)NCc1ccccc1 InChI=1S/C17H17FN2O3/c18-14-8-6-12(7-9-14)10-15(17(22)20-23)16(21)19-11-13-4-2-1-3-5-13/h1-9,15,23H,10-11H2,(H,19,21)(H,20,22) UBULRDFJXZRBJH-UHFFFAOYSA-N 50400206 CHEMBL2180993 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1021/acsmedchemlett.6b00505 10.7270/Q26M390J 28337326 Mpakali, A; Giastas, P; Deprez-Poulain, R; Papakyriakou, A; Koumantou, D; Gealageas, R; Tsoukalidou, S; Vourloumis, D; Mavridis, IM; Stratikos, E; Saridakis, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400206&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 6GA 5J6S 71457393 163349230 CHEMBL2180993 ZINC95576973 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50555797 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 50 ChEMBL 10.1021/acsmedchemlett.6b00505 10.7270/Q26M390J 28337326 Mpakali, A; Giastas, P; Deprez-Poulain, R; Papakyriakou, A; Koumantou, D; Gealageas, R; Tsoukalidou, S; Vourloumis, D; Mavridis, IM; Stratikos, E; Saridakis, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50555798 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)[C@@H](N)CCCNC(N)=N)c1 InChI=1S/C23H31N7O5/c1-35-22(34)19(11-13-4-7-15(31)8-5-13)30-20(32)14-6-9-16(24)18(12-14)29-21(33)17(25)3-2-10-28-23(26)27/h4-9,12,17,19,31H,2-3,10-11,24-25H2,1H3,(H,29,33)(H,30,32)(H4,26,27,28)/t17-,19-/m0/s1 JECKMXQKZJERLG-HKUYNNGSSA-N 50076971 CHEMBL3416696 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2000 ChEMBL 10.1021/acsmedchemlett.6b00505 10.7270/Q26M390J 28337326 Mpakali, A; Giastas, P; Deprez-Poulain, R; Papakyriakou, A; Koumantou, D; Gealageas, R; Tsoukalidou, S; Vourloumis, D; Mavridis, IM; Stratikos, E; Saridakis, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076971&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 6PX 5K1V 118734263 313048494 CHEMBL3416696 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50740744 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H40N3O4P/c36-33(22-21-26-13-5-1-6-14-26)43(41,42)25-30(35(40)38-32(34(37)39)23-27-15-7-2-8-16-27)24-31(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30-33H,21-25,36H2,(H2,37,39)(H,38,40)(H,41,42)/t30-,32+,33-/m1/s1 FDAGDZVCWKCEEX-NGYIUDBNSA-N 50236826 CHEMBL4065841 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 200 ChEMBL 10.1021/acs.jmedchem.6b01890 10.7270/Q29G5Q35 28328206 Mpakali, A; Saridakis, E; Harlos, K; Zhao, Y; Kokkala, P; Georgiadis, D; Giastas, P; Papakyriakou, A; Stratikos, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236826&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 7O2 5MJ6 126456392 385453345 CHEMBL4065841 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766330 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](C)C(N)=O InChI=1S/C19H32N3O4P/c1-13(2)11-16(19(24)22-14(3)18(21)23)12-27(25,26)17(20)10-9-15-7-5-4-6-8-15/h4-8,13-14,16-17H,9-12,20H2,1-3H3,(H2,21,23)(H,22,24)(H,25,26)/t14-,16+,17+/m0/s1 AZIAPQRBCIAHTO-USXIJHARSA-N 50245460 CHEMBL4091951 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 96 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245460&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137652734 386403432 CHEMBL4091951 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766334 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C25H36N3O4P/c1-18(2)15-21(17-33(31,32)23(26)14-13-19-9-5-3-6-10-19)25(30)28-22(24(27)29)16-20-11-7-4-8-12-20/h3-12,18,21-23H,13-17,26H2,1-2H3,(H2,27,29)(H,28,30)(H,31,32)/t21-,22+,23-/m1/s1 BUDSAEMPVYFKML-XPWALMASSA-N 50245348 CHEMBL4099693 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 109 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245348&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137662110 386403406 CHEMBL4099693 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766342 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N1CCC[C@H]1C(N)=O InChI=1S/C21H34N3O4P/c1-15(2)13-17(21(26)24-12-6-9-18(24)20(23)25)14-29(27,28)19(22)11-10-16-7-4-3-5-8-16/h3-5,7-8,15,17-19H,6,9-14,22H2,1-2H3,(H2,23,25)(H,27,28)/t17-,18+,19-/m1/s1 NJCHEVDWMWFDNQ-CEXWTWQISA-N 50245349 CHEMBL4089555 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 144 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245349&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137641900 386403407 CHEMBL4089555 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766344 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O InChI=1S/C25H36N3O5P/c1-17(2)14-20(16-34(32,33)23(26)13-10-18-6-4-3-5-7-18)25(31)28-22(24(27)30)15-19-8-11-21(29)12-9-19/h3-9,11-12,17,20,22-23,29H,10,13-16,26H2,1-2H3,(H2,27,30)(H,28,31)(H,32,33)/t20-,22+,23-/m1/s1 SAZVKYFGANAWRA-AKIFATBCSA-N 50245354 CHEMBL4097268 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 55 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245354&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137661774 386403408 CHEMBL4097268 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766364 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](CO)C(N)=O InChI=1S/C19H32N3O5P/c1-13(2)10-15(19(25)22-16(11-23)18(21)24)12-28(26,27)17(20)9-8-14-6-4-3-5-7-14/h3-7,13,15-17,23H,8-12,20H2,1-2H3,(H2,21,24)(H,22,25)(H,26,27)/t15-,16+,17-/m1/s1 LWTGCDBTARLXAS-IXDOHACOSA-N 50245355 CHEMBL4070078 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 129 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245355&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137639983 386403409 CHEMBL4070078 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766366 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O InChI=1S/C22H39N4O4P/c1-16(2)14-18(22(28)26-19(21(25)27)10-6-7-13-23)15-31(29,30)20(24)12-11-17-8-4-3-5-9-17/h3-5,8-9,16,18-20H,6-7,10-15,23-24H2,1-2H3,(H2,25,27)(H,26,28)(H,29,30)/t18-,19+,20-/m1/s1 WSLSICGDZUFJKP-HSALFYBXSA-N 50245398 CHEMBL4088020 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 271 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245398&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137642974 386403421 CHEMBL4088020 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766367 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(N)=O InChI=1S/C21H34N3O6P/c1-14(2)12-16(21(28)24-17(20(23)27)9-11-19(25)26)13-31(29,30)18(22)10-8-15-6-4-3-5-7-15/h3-7,14,16-18H,8-13,22H2,1-2H3,(H2,23,27)(H,24,28)(H,25,26)(H,29,30)/t16-,17+,18-/m1/s1 RQHWXFMDLINVRK-FGTMMUONSA-N 50245366 CHEMBL4095735 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 243 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245366&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137655020 104101125 CHEMBL4095735 ZINC40863412 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766368 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(N)=O InChI=1S/C25H36N3O4P/c1-18(2)15-21(17-33(31,32)23(26)14-13-19-9-5-3-6-10-19)25(30)28-22(24(27)29)16-20-11-7-4-8-12-20/h3-12,18,21-23H,13-17,26H2,1-2H3,(H2,27,29)(H,28,30)(H,31,32)/t21-,22-,23-/m1/s1 BUDSAEMPVYFKML-DNVJHFABSA-N 50245380 CHEMBL4077711 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 211 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245380&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137650752 386403411 CHEMBL4077711 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766372 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(no1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H35N4O5P/c32-29(17-16-22-10-4-1-5-11-22)41(38,39)21-25(19-26-20-27(35-40-26)24-14-8-3-9-15-24)31(37)34-28(30(33)36)18-23-12-6-2-7-13-23/h1-15,20,25,28-29H,16-19,21,32H2,(H2,33,36)(H,34,37)(H,38,39)/t25-,28+,29-/m1/s1 YNFZCLOZANIMIN-QUFBTCJSSA-N 50245399 CHEMBL4069425 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 190 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245399&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137634250 386403422 CHEMBL4069425 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766375 COc1ccccc1-c1cc(C[C@H](CP(O)(=O)[C@@H](N)CCc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)on1 InChI=1S/C32H37N4O6P/c1-41-29-15-9-8-14-26(29)27-20-25(42-36-27)19-24(21-43(39,40)30(33)17-16-22-10-4-2-5-11-22)32(38)35-28(31(34)37)18-23-12-6-3-7-13-23/h2-15,20,24,28,30H,16-19,21,33H2,1H3,(H2,34,37)(H,35,38)(H,39,40)/t24-,28+,30-/m1/s1 PAISIGRMLVYIDB-SHFQUTHWSA-N 50245382 CHEMBL4080145 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 130 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245382&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137646849 386403413 CHEMBL4080145 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766378 COc1cccc(c1)-c1cc(C[C@H](CP(O)(=O)[C@@H](N)CCc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)on1 InChI=1S/C32H37N4O6P/c1-41-26-14-8-13-24(18-26)28-20-27(42-36-28)19-25(21-43(39,40)30(33)16-15-22-9-4-2-5-10-22)32(38)35-29(31(34)37)17-23-11-6-3-7-12-23/h2-14,18,20,25,29-30H,15-17,19,21,33H2,1H3,(H2,34,37)(H,35,38)(H,39,40)/t25-,29+,30-/m1/s1 WWZWLDVQUBJSGD-TZFWCWEWSA-N 50245383 CHEMBL4104383 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 217 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245383&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137658289 386403414 CHEMBL4104383 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766387 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(no1)-c1ccccc1Cl)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H34ClN4O5P/c32-26-14-8-7-13-25(26)27-19-24(41-36-27)18-23(20-42(39,40)29(33)16-15-21-9-3-1-4-10-21)31(38)35-28(30(34)37)17-22-11-5-2-6-12-22/h1-14,19,23,28-29H,15-18,20,33H2,(H2,34,37)(H,35,38)(H,39,40)/t23-,28+,29-/m1/s1 WVARWRXWGWJNRJ-LDVROUIZSA-N 50245388 CHEMBL4081073 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 123 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245388&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137648545 386403415 CHEMBL4081073 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766398 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(no1)-c1cccc(Cl)c1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H34ClN4O5P/c32-25-13-7-12-23(17-25)27-19-26(41-36-27)18-24(20-42(39,40)29(33)15-14-21-8-3-1-4-9-21)31(38)35-28(30(34)37)16-22-10-5-2-6-11-22/h1-13,17,19,24,28-29H,14-16,18,20,33H2,(H2,34,37)(H,35,38)(H,39,40)/t24-,28+,29-/m1/s1 IEYYHWFOJFXPGP-OFQAEJFBSA-N 50245389 CHEMBL4085707 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 225 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245389&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137646376 386403416 CHEMBL4085707 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766410 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(no1)-c1ccc(Cl)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H34ClN4O5P/c32-25-14-12-23(13-15-25)27-19-26(41-36-27)18-24(20-42(39,40)29(33)16-11-21-7-3-1-4-8-21)31(38)35-28(30(34)37)17-22-9-5-2-6-10-22/h1-10,12-15,19,24,28-29H,11,16-18,20,33H2,(H2,34,37)(H,35,38)(H,39,40)/t24-,28+,29-/m1/s1 ASBAZJSDHGVMRZ-OFQAEJFBSA-N 50245401 CHEMBL4103640 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 345 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245401&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137657323 386403424 CHEMBL4103640 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766422 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(no1)-c1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H35N4O6P/c32-29(16-11-21-7-3-1-4-8-21)42(39,40)20-24(18-26-19-27(35-41-26)23-12-14-25(36)15-13-23)31(38)34-28(30(33)37)17-22-9-5-2-6-10-22/h1-10,12-15,19,24,28-29,36H,11,16-18,20,32H2,(H2,33,37)(H,34,38)(H,39,40)/t24-,28+,29-/m1/s1 JEQPENJEYBAHIE-OFQAEJFBSA-N 50245391 CHEMBL4095882 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 56 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245391&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137655030 386403418 CHEMBL4095882 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766438 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC#C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C24H30N3O4P/c1-2-9-20(17-32(30,31)22(25)15-14-18-10-5-3-6-11-18)24(29)27-21(23(26)28)16-19-12-7-4-8-13-19/h1,3-8,10-13,20-22H,9,14-17,25H2,(H2,26,28)(H,27,29)(H,30,31)/t20-,21+,22-/m1/s1 QCPJTEUURKCRNT-BHIFYINESA-N 50245396 CHEMBL4101200 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 37 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245396&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137660529 386403419 CHEMBL4101200 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766444 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H44N3O4P/c33-29(12-11-22-7-3-1-4-8-22)40(38,39)21-27(20-32-17-24-13-25(18-32)15-26(14-24)19-32)31(37)35-28(30(34)36)16-23-9-5-2-6-10-23/h1-10,24-29H,11-21,33H2,(H2,34,36)(H,35,37)(H,38,39)/t24?,25?,26?,27-,28+,29-,32?/m1/s1 BUSBNAUESVLLQC-QLOXJZRISA-N 50245402 CHEMBL4074464 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 412 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245402&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137640590 386403425 CHEMBL4074464 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766450 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H40N3O4P/c36-33(22-21-26-13-5-1-6-14-26)43(41,42)25-30(35(40)38-32(34(37)39)23-27-15-7-2-8-16-27)24-31(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30-33H,21-25,36H2,(H2,37,39)(H,38,40)(H,41,42)/t30-,32+,33-/m1/s1 FDAGDZVCWKCEEX-NGYIUDBNSA-N 50236826 CHEMBL4065841 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 740 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50236826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50236826&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 7O2 5MJ6 126456392 385453345 CHEMBL4065841 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766454 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@H](CC(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C35H40N3O4P/c36-33(22-21-26-13-5-1-6-14-26)43(41,42)25-30(35(40)38-32(34(37)39)23-27-15-7-2-8-16-27)24-31(28-17-9-3-10-18-28)29-19-11-4-12-20-29/h1-20,30-33H,21-25,36H2,(H2,37,39)(H,38,40)(H,41,42)/t30-,32-,33+/m0/s1 FDAGDZVCWKCEEX-FLPLPDKSSA-N 50245427 CHEMBL4096799 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1922 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245427&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137653412 386403426 CHEMBL4096799 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766481 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(cc(c1)-c1ccccc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C40H42N3O4P/c41-38(22-21-29-13-5-1-6-14-29)48(46,47)28-36(40(45)43-37(39(42)44)26-30-15-7-2-8-16-30)25-31-23-34(32-17-9-3-10-18-32)27-35(24-31)33-19-11-4-12-20-33/h1-20,23-24,27,36-38H,21-22,25-26,28,41H2,(H2,42,44)(H,43,45)(H,46,47)/t36-,37+,38-/m1/s1 KAKJFMITKIMUAY-NVLDWDGTSA-N 50245446 CHEMBL4094131 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 105 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245446&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137654495 386403431 CHEMBL4094131 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766513 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@H](Cc1cc(cc(c1)-c1ccccc1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C40H42N3O4P/c41-38(22-21-29-13-5-1-6-14-29)48(46,47)28-36(40(45)43-37(39(42)44)26-30-15-7-2-8-16-30)25-31-23-34(32-17-9-3-10-18-32)27-35(24-31)33-19-11-4-12-20-33/h1-20,23-24,27,36-38H,21-22,25-26,28,41H2,(H2,42,44)(H,43,45)(H,46,47)/t36-,37-,38+/m0/s1 KAKJFMITKIMUAY-XEZIGOATSA-N 50245429 CHEMBL4073490 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4622 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245429&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137640549 386403428 CHEMBL4073490 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766514 CC(C)C[C@H](NC(=O)[C@H](Cc1cc(cc(c1)-c1ccccc1)-c1ccccc1)CP(O)(=O)[C@@H](N)CCc1ccccc1)C(N)=O InChI=1S/C37H44N3O4P/c1-26(2)20-34(36(39)41)40-37(42)33(25-45(43,44)35(38)19-18-27-12-6-3-7-13-27)23-28-21-31(29-14-8-4-9-15-29)24-32(22-28)30-16-10-5-11-17-30/h3-17,21-22,24,26,33-35H,18-20,23,25,38H2,1-2H3,(H2,39,41)(H,40,42)(H,43,44)/t33-,34+,35-/m1/s1 RAXDQSLZABPHNA-GVBYMILNSA-N 50245430 CHEMBL4086352 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2565 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245430&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 7OO 7PFS 137642894 386403429 CHEMBL4086352 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766563 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(N)=O InChI=1S/C22H38N3O4P/c1-15(2)12-18(22(27)25-19(21(24)26)13-16(3)4)14-30(28,29)20(23)11-10-17-8-6-5-7-9-17/h5-9,15-16,18-20H,10-14,23H2,1-4H3,(H2,24,26)(H,25,27)(H,28,29)/t18-,19+,20-/m1/s1 AATVMVZMTDKRJI-HSALFYBXSA-N 50245347 CHEMBL4081682 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 118 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245347&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137647165 386403405 CHEMBL4081682 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766564 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 80 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766566 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(N)=O InChI=1S/C22H34N5O4P/c1-15(2)10-17(22(29)27-19(21(24)28)11-18-12-25-14-26-18)13-32(30,31)20(23)9-8-16-6-4-3-5-7-16/h3-7,12,14-15,17,19-20H,8-11,13,23H2,1-2H3,(H2,24,28)(H,25,26)(H,27,29)(H,30,31)/t17-,19+,20-/m1/s1 WWNSEAAJQAYPMS-YZGWKJHDSA-N 50245356 CHEMBL4066723 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 128 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245356&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137633011 386403410 CHEMBL4066723 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766567 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@H](Cc1cc(no1)-c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H35N4O5P/c32-29(17-16-22-10-4-1-5-11-22)41(38,39)21-25(19-26-20-27(35-40-26)24-14-8-3-9-15-24)31(37)34-28(30(33)36)18-23-12-6-2-7-13-23/h1-15,20,25,28-29H,16-19,21,32H2,(H2,33,36)(H,34,37)(H,38,39)/t25-,28-,29+/m0/s1 YNFZCLOZANIMIN-OWPQXHQJSA-N 50245381 CHEMBL4096656 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 878 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245381&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137655972 386403412 CHEMBL4096656 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766568 COc1ccc(cc1)-c1cc(C[C@H](CP(O)(=O)[C@@H](N)CCc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)on1 InChI=1S/C32H37N4O6P/c1-41-26-15-13-24(14-16-26)28-20-27(42-36-28)19-25(21-43(39,40)30(33)17-12-22-8-4-2-5-9-22)32(38)35-29(31(34)37)18-23-10-6-3-7-11-23/h2-11,13-16,20,25,29-30H,12,17-19,21,33H2,1H3,(H2,34,37)(H,35,38)(H,39,40)/t25-,29+,30-/m1/s1 QJVIFKMCLOJOGV-TZFWCWEWSA-N 50245400 CHEMBL4099107 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 84 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245400&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137659752 386403423 CHEMBL4099107 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766569 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](Cc1cc(no1)-c1ccccc1O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C31H35N4O6P/c32-29(16-15-21-9-3-1-4-10-21)42(39,40)20-23(18-24-19-26(35-41-24)25-13-7-8-14-28(25)36)31(38)34-27(30(33)37)17-22-11-5-2-6-12-22/h1-14,19,23,27,29,36H,15-18,20,32H2,(H2,33,37)(H,34,38)(H,39,40)/t23-,27+,29-/m1/s1 GSWUIYHGTPVQDP-FNHKZSGOSA-N 50245390 CHEMBL4077855 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 83 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245390&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 62S 7P7P 137650040 386403417 CHEMBL4077855 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766570 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@H](CC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C32H44N3O4P/c33-29(12-11-22-7-3-1-4-8-22)40(38,39)21-27(20-32-17-24-13-25(18-32)15-26(14-24)19-32)31(37)35-28(30(34)36)16-23-9-5-2-6-10-23/h1-10,24-29H,11-21,33H2,(H2,34,36)(H,35,37)(H,38,39)/t24?,25?,26?,27-,28-,29+,32?/m0/s1 BUSBNAUESVLLQC-KWLTVRMTSA-N 50245397 CHEMBL4093454 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2271 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245397&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137656080 386403420 CHEMBL4093454 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766574 CC(C)C[C@H](NC(=O)[C@H](CC(c1ccccc1)c1ccccc1)CP(O)(=O)[C@@H](N)CCc1ccccc1)C(N)=O InChI=1S/C32H42N3O4P/c1-23(2)20-29(31(34)36)35-32(37)27(22-40(38,39)30(33)19-18-24-12-6-3-7-13-24)21-28(25-14-8-4-9-15-25)26-16-10-5-11-17-26/h3-17,23,27-30H,18-22,33H2,1-2H3,(H2,34,36)(H,35,37)(H,38,39)/t27-,29+,30-/m1/s1 KFHOCODEDHRRMQ-CCNCKIRNSA-N 50245428 CHEMBL4069576 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 246 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245428&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137638141 386403427 CHEMBL4069576 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 50766575 CC(C)C[C@H](NC(=O)[C@H](Cc1cc(cc(c1)-c1cccc(Cl)c1)-c1cccc(Cl)c1)CP(O)(=O)[C@@H](N)CCc1ccccc1)C(N)=O InChI=1S/C37H42Cl2N3O4P/c1-24(2)16-34(36(41)43)42-37(44)31(23-47(45,46)35(40)15-14-25-8-4-3-5-9-25)19-26-17-29(27-10-6-12-32(38)21-27)20-30(18-26)28-11-7-13-33(39)22-28/h3-13,17-18,20-22,24,31,34-35H,14-16,19,23,40H2,1-2H3,(H2,41,43)(H,42,44)(H,45,46)/t31-,34+,35-/m1/s1 OZHIFGOMORPPQM-ZCLHRBOTSA-N 50245437 CHEMBL4064891 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 13814 ChEMBL 10.1021/acs.jmedchem.6b01031 10.7270/Q2PK0JJG 27606717 Kokkala, P; Mpakali, A; Mauvais, FX; Papakyriakou, A; Daskalaki, I; Petropoulou, I; Kavvalou, S; Papathanasopoulou, M; Agrotis, S; Fonsou, TM; van Endert, P; Stratikos, E; Georgiadis, D National and Kapodistrian University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245437&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137637900 386403430 CHEMBL4064891 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51259550 N.C[C@@H]1C[C@H](O)[C@]2(C)[C@H](CCC=C2C(O)=O)[C@@]1(C)CCc1ccoc1 InChI=1S/C20H28O4.H3N/c1-13-11-17(21)20(3)15(18(22)23)5-4-6-16(20)19(13,2)9-7-14-8-10-24-12-14;/h5,8,10,12-13,16-17,21H,4,6-7,9,11H2,1-3H3,(H,22,23);1H3/t13-,16-,17+,19+,20+;/m1./s1 QENGBUDRUMRCDR-CGTWFDGSSA-N 50514671 CHEMBL4532803 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <158489 ChEMBL 10.1021/acs.jmedchem.9b02123 10.7270/Q2TM7FF4 32109056 Liddle, J; Hutchinson, JP; Kitchen, S; Rowland, P; Neu, M; Cecconie, T; Holmes, DS; Jones, E; Korczynska, J; Koumantou, D; Lea, JD; Nickels, L; Pemberton, M; Phillipou, A; Schneck, JL; Sheehan, H; Tinworth, CP; Uings, I; Wojno-Picon, J; Young, RJ; Stratikos, E GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50514671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50514671&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155547335 440723253 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51232745 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CCC(c1ccccc1)c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C36H42N3O4P/c37-34(24-21-27-13-5-1-6-14-27)44(42,43)26-31(36(41)39-33(35(38)40)25-28-15-7-2-8-16-28)22-23-32(29-17-9-3-10-18-29)30-19-11-4-12-20-30/h1-20,31-34H,21-26,37H2,(H2,38,40)(H,39,41)(H,42,43)/t31-,33+,34-/m1/s1 HUKAXHQRFRZFBN-PNIVXLCQSA-N 50505150 CHEMBL4537224 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 740 ChEMBL 10.1016/j.bmcl.2019.02.034 10.7270/Q2DR2ZSK 30846252 Talma, M; Maślanka, M; Mucha, A Wroc?aw University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50505150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50505150&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155548478 440713735 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51232754 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC#C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C24H30N3O4P/c1-2-9-20(17-32(30,31)22(25)15-14-18-10-5-3-6-11-18)24(29)27-21(23(26)28)16-19-12-7-4-8-13-19/h1,3-8,10-13,20-22H,9,14-17,25H2,(H2,26,28)(H,27,29)(H,30,31)/t20-,21+,22-/m1/s1 QCPJTEUURKCRNT-BHIFYINESA-N 50245396 CHEMBL4101200 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 37 ChEMBL 10.1016/j.bmcl.2019.02.034 10.7270/Q2DR2ZSK 30846252 Talma, M; Maślanka, M; Mucha, A Wroc?aw University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245396&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137660529 386403419 CHEMBL4101200 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273955 CC(=O)N1CCN(CC1)C(=O)C1(CC1)NC(=N)Nc1ccc(C)cc1 InChI=1S/C18H25N5O2/c1-13-3-5-15(6-4-13)20-17(19)21-18(7-8-18)16(25)23-11-9-22(10-12-23)14(2)24/h3-6H,7-12H2,1-2H3,(H3,19,20,21) GWKLFFRDFHVVKM-UHFFFAOYSA-N 50519942 CHEMBL4437748 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519942&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155512732 440728524 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273970 Fc1ccc(F)c(c1)S(=O)(=O)NC(=N)NCCc1c[nH]c2ccccc12 InChI=1S/C17H16F2N4O2S/c18-12-5-6-14(19)16(9-12)26(24,25)23-17(20)21-8-7-11-10-22-15-4-2-1-3-13(11)15/h1-6,9-10,22H,7-8H2,(H3,20,21,23) KLIVXGVUVONPGE-UHFFFAOYSA-N 50519948 CHEMBL1700161 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <1000000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519948&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 7197248 440728530 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273971 COc1ccc(cc1S(=O)(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F)C(O)=O InChI=1S/C20H21F3N2O5S/c1-30-17-8-5-13(19(26)27)11-18(17)31(28,29)24-15-12-14(20(21,22)23)6-7-16(15)25-9-3-2-4-10-25/h5-8,11-12,24H,2-4,9-10H2,1H3,(H,26,27) NDYXAJZYGMHQDN-UHFFFAOYSA-N 50519953 CHEMBL2140832 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519953&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 4798291 440728535 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273972 CC(=O)N1CCN(CC1)C(=O)C1(CCCCC1)NC(=N)Nc1ccc(F)cc1 InChI=1S/C20H28FN5O2/c1-15(27)25-11-13-26(14-12-25)18(28)20(9-3-2-4-10-20)24-19(22)23-17-7-5-16(21)6-8-17/h5-8H,2-4,9-14H2,1H3,(H3,22,23,24) GJPOCZOQAVLXBQ-UHFFFAOYSA-N 50519946 CHEMBL4444617 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519946&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155517480 440728528 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273973 CC(=O)N1CCN(CC1)C(=O)C1(CCCCC1)NC(=N)Nc1ccccc1 InChI=1S/C20H29N5O2/c1-16(26)24-12-14-25(15-13-24)18(27)20(10-6-3-7-11-20)23-19(21)22-17-8-4-2-5-9-17/h2,4-5,8-9H,3,6-7,10-15H2,1H3,(H3,21,22,23) DMCYRBDLXRXJNF-UHFFFAOYSA-N 50519947 CHEMBL4515471 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519947&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155539882 440728529 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273974 Cc1ccc(NC(=N)NC2(CCCCC2)C(=O)N2CCN(CC2)c2ccccc2)cc1 InChI=1S/C25H33N5O/c1-20-10-12-21(13-11-20)27-24(26)28-25(14-6-3-7-15-25)23(31)30-18-16-29(17-19-30)22-8-4-2-5-9-22/h2,4-5,8-13H,3,6-7,14-19H2,1H3,(H3,26,27,28) JPQYJKLFYUONII-UHFFFAOYSA-N 50519954 CHEMBL4434818 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519954&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155510769 440728536 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273975 OC(=O)c1ccc(Br)c(c1)S(=O)(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F InChI=1S/C19H18BrF3N2O4S/c20-14-6-4-12(18(26)27)10-17(14)30(28,29)24-15-11-13(19(21,22)23)5-7-16(15)25-8-2-1-3-9-25/h4-7,10-11,24H,1-3,8-9H2,(H,26,27) ARGCZAMLVSKEHU-UHFFFAOYSA-N 50519950 CHEMBL4578212 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519950&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 85470733 440728532 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273976 COc1ccc(cc1S(=O)(=O)Nc1cc(F)ccc1N1CCCCC1)C(O)=O InChI=1S/C19H21FN2O5S/c1-27-17-8-5-13(19(23)24)11-18(17)28(25,26)21-15-12-14(20)6-7-16(15)22-9-3-2-4-10-22/h5-8,11-12,21H,2-4,9-10H2,1H3,(H,23,24) UBKLNIFGBDJHPL-UHFFFAOYSA-N 50519955 CHEMBL4587278 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 159000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519955&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 73437637 440728537 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273977 COc1ccc(cc1S(=O)(=O)Nc1ccccc1N1CCCCC1)C(O)=O InChI=1S/C19H22N2O5S/c1-26-17-10-9-14(19(22)23)13-18(17)27(24,25)20-15-7-3-4-8-16(15)21-11-5-2-6-12-21/h3-4,7-10,13,20H,2,5-6,11-12H2,1H3,(H,22,23) PZYXFJPRKRQPRG-UHFFFAOYSA-N 50519956 CHEMBL4558482 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 81200 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519956&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 25760265 440728538 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273996 CC(=O)N1CCN(CC1)C(=O)C1(CCCCC1)NC(=N)Nc1ccc(Cl)cc1 InChI=1S/C20H28ClN5O2/c1-15(27)25-11-13-26(14-12-25)18(28)20(9-3-2-4-10-20)24-19(22)23-17-7-5-16(21)6-8-17/h5-8H,2-4,9-14H2,1H3,(H3,22,23,24) IKYQZCFHBRXCIV-UHFFFAOYSA-N 50519957 CHEMBL4586487 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519957&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155566815 440728539 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51273997 OC(=O)c1ccc(Cl)c(c1)S(=O)(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F InChI=1S/C19H18ClF3N2O4S/c20-14-6-4-12(18(26)27)10-17(14)30(28,29)24-15-11-13(19(21,22)23)5-7-16(15)25-8-2-1-3-9-25/h4-7,10-11,24H,1-3,8-9H2,(H,26,27) OUEUQOFGGRRASZ-UHFFFAOYSA-N 50519949 CHEMBL4458647 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519949&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 85470742 440728531 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51274000 COc1ccc(cc1S(=O)(=O)N(C)c1cc(ccc1N1CCCCC1)C(F)(F)F)C(O)=O InChI=1S/C21H23F3N2O5S/c1-25(32(29,30)19-12-14(20(27)28)6-9-18(19)31-2)17-13-15(21(22,23)24)7-8-16(17)26-10-4-3-5-11-26/h6-9,12-13H,3-5,10-11H2,1-2H3,(H,27,28) NOASDKSTYOVNJF-UHFFFAOYSA-N 50519940 CHEMBL4476531 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 160000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519940&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 86222557 440728522 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51274003 OC(=O)c1cccc(c1)S(=O)(=O)Nc1cc(ccc1N1CCCCC1)C(F)(F)F InChI=1S/C19H19F3N2O4S/c20-19(21,22)14-7-8-17(24-9-2-1-3-10-24)16(12-14)23-29(27,28)15-6-4-5-13(11-15)18(25)26/h4-8,11-12,23H,1-3,9-10H2,(H,25,26) TZCSQVCSJPQJGT-UHFFFAOYSA-N 50519951 CHEMBL4439709 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 140000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519951&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 45464518 440728533 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51274010 COc1ccc(NC(=N)NC2(CCCCC2)C(=O)N2CCN(CC2)C(C)=O)cc1 InChI=1S/C21H31N5O3/c1-16(27)25-12-14-26(15-13-25)19(28)21(10-4-3-5-11-21)24-20(22)23-17-6-8-18(29-2)9-7-17/h6-9H,3-5,10-15H2,1-2H3,(H3,22,23,24) IEYXYKRAGRFJLX-UHFFFAOYSA-N 50519945 CHEMBL4442299 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519945&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155515712 440728527 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51274011 CC(=O)N1CCN(CC1)C(=O)C(C)(C)NC(=N)Nc1ccc(C)cc1 InChI=1S/C18H27N5O2/c1-13-5-7-15(8-6-13)20-17(19)21-18(3,4)16(25)23-11-9-22(10-12-23)14(2)24/h5-8H,9-12H2,1-4H3,(H3,19,20,21) NXHQEFIUSDYKIN-UHFFFAOYSA-N 50519959 CHEMBL4438051 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519959&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155512960 440728541 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51274020 Cc1ccc(NC(=N)NC2(CCCCC2)C(=O)N2CCOCC2)cc1 InChI=1S/C19H28N4O2/c1-15-5-7-16(8-6-15)21-18(20)22-19(9-3-2-4-10-19)17(24)23-11-13-25-14-12-23/h5-8H,2-4,9-14H2,1H3,(H3,20,21,22) ZXIKFNGJFRBASI-UHFFFAOYSA-N 50519943 CHEMBL4470719 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >200000 ChEMBL 10.1021/acs.jmedchem.9b00293 10.7270/Q2DN48D3 31841350 Maben, Z; Arya, R; Rane, D; An, WF; Metkar, S; Hickey, M; Bender, S; Ali, A; Nguyen, TT; Evnouchidou, I; Schilling, R; Stratikos, E; Golden, J; Stern, LJ Kansas University Specialized Chemistry Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519943&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155534671 440728525 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51316300 Clc1ccc(COc2ccc(cc2)-c2cc([nH]n2)C(=O)N\N=C\c2c[nH]c3ccccc23)cc1 InChI=1S/C26H20ClN5O2/c27-20-9-5-17(6-10-20)16-34-21-11-7-18(8-12-21)24-13-25(31-30-24)26(33)32-29-15-19-14-28-23-4-2-1-3-22(19)23/h1-15,28H,16H2,(H,30,31)(H,32,33)/b29-15+ CSXUQZMURGRPLY-WKULSOCRSA-N 50533143 CHEMBL4458354 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 34000 ChEMBL 10.1021/acsmedchemlett.6b00084 10.7270/Q29P3549 27437077 Stamogiannos, A; Papakyriakou, A; Mauvais, FX; van Endert, P; Stratikos, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533143&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 135554374 440741725 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51316304 Clc1ccc(COc2ccc(cc2)-c2cc([nH]n2)C(=O)N\N=C\c2c[nH]c3ccccc23)cc1 InChI=1S/C26H20ClN5O2/c27-20-9-5-17(6-10-20)16-34-21-11-7-18(8-12-21)24-13-25(31-30-24)26(33)32-29-15-19-14-28-23-4-2-1-3-22(19)23/h1-15,28H,16H2,(H,30,31)(H,32,33)/b29-15+ CSXUQZMURGRPLY-WKULSOCRSA-N 50533143 CHEMBL4458354 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 34000 ChEMBL 10.1021/acsmedchemlett.6b00084 10.7270/Q29P3549 27437077 Stamogiannos, A; Papakyriakou, A; Mauvais, FX; van Endert, P; Stratikos, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533143&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 135554374 440741725 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298844 CCCC[C@H](N)C(=O)Nc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H34N4O4/c1-2-3-12-26(32)30(37)34-24-16-14-22(15-17-24)29(36)35-28(31(38)39-20-21-9-5-4-6-10-21)18-23-19-33-27-13-8-7-11-25(23)27/h4-11,13-17,19,26,28,33H,2-3,12,18,20,32H2,1H3,(H,34,37)(H,35,36)/t26-,28-/m0/s1 YNBUILPSIRWOEF-XCZPVHLTSA-N 50529321 CHEMBL4575946 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8800 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529321&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155564248 440737903 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298854 Oc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=O InChI=1S/C21H20N2O3/c24-19-7-4-14-23(21(19)26)15-20(25)22-13-12-16-8-10-18(11-9-16)17-5-2-1-3-6-17/h1-11,14,24H,12-13,15H2,(H,22,25) XKRQSRFKBWMVSU-UHFFFAOYSA-N 50529324 CHEMBL4445197 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 50300 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529324&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search K8T 6RLY 145994843 440737906 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298855 Oc1cccn(CC(=O)NCCc2c[nH]c3ccccc23)c1=O InChI=1S/C17H17N3O3/c21-15-6-3-9-20(17(15)23)11-16(22)18-8-7-12-10-19-14-5-2-1-4-13(12)14/h1-6,9-10,19,21H,7-8,11H2,(H,18,22) NRCSONGNAATKNC-UHFFFAOYSA-N 50529327 CHEMBL4455738 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 31300 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529327&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search K0Q 6RD0 145925583 440737909 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298856 COc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=S InChI=1S/C22H22N2O2S/c1-26-20-8-5-15-24(22(20)27)16-21(25)23-14-13-17-9-11-19(12-10-17)18-6-3-2-4-7-18/h2-12,15H,13-14,16H2,1H3,(H,23,25) DHHBMHIBSJVIFD-UHFFFAOYSA-N 50529328 CHEMBL4475441 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 31900 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529328&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155538090 440737910 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298857 CCCC[C@H](N)C(=O)Nc1cccc(c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H34N4O4/c1-2-3-15-26(32)30(37)34-24-13-9-12-22(17-24)29(36)35-28(31(38)39-20-21-10-5-4-6-11-21)18-23-19-33-27-16-8-7-14-25(23)27/h4-14,16-17,19,26,28,33H,2-3,15,18,20,32H2,1H3,(H,34,37)(H,35,36)/t26-,28-/m0/s1 DXLWSWYDJYDERB-XCZPVHLTSA-N 50529329 CHEMBL4560993 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529329&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155558560 440737911 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298858 CCCC[C@H](N)C(=O)NNc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H35N5O4/c1-2-3-12-26(32)30(38)36-35-24-16-14-22(15-17-24)29(37)34-28(31(39)40-20-21-9-5-4-6-10-21)18-23-19-33-27-13-8-7-11-25(23)27/h4-11,13-17,19,26,28,33,35H,2-3,12,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1 ZWCJCHLBYMDNAF-XCZPVHLTSA-N 50529330 CHEMBL4527760 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2200 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529330&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155545269 440737912 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298859 N[C@@H](CCc1ccccc1)C(=O)NNc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C35H35N5O4/c36-30(20-15-24-9-3-1-4-10-24)34(42)40-39-28-18-16-26(17-19-28)33(41)38-32(35(43)44-23-25-11-5-2-6-12-25)21-27-22-37-31-14-8-7-13-29(27)31/h1-14,16-19,22,30,32,37,39H,15,20-21,23,36H2,(H,38,41)(H,40,42)/t30-,32-/m0/s1 PUXBRTPTSSVXFL-CDZUIXILSA-N 50529323 CHEMBL4452852 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529323&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155523459 440737905 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298867 Oc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=O InChI=1S/C21H20N2O3/c24-19-7-4-14-23(21(19)26)15-20(25)22-13-12-16-8-10-18(11-9-16)17-5-2-1-3-6-17/h1-11,14,24H,12-13,15H2,(H,22,25) XKRQSRFKBWMVSU-UHFFFAOYSA-N 50529324 CHEMBL4445197 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 27400 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529324&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search K8T 6RLY 145994843 440737906 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298868 OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn1cccc(O)c1=O InChI=1S/C18H17N3O5/c22-15-6-3-7-21(17(15)24)10-16(23)20-14(18(25)26)8-11-9-19-13-5-2-1-4-12(11)13/h1-7,9,14,19,22H,8,10H2,(H,20,23)(H,25,26)/t14-/m0/s1 GBAYREVXHGRLPG-AWEZNQCLSA-N 50529331 CHEMBL4535014 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 21400 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529331&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155547553 440737913 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298869 COc1cccn(CC(=O)NCCc2ccc(cc2)-c2ccccc2)c1=S InChI=1S/C22H22N2O2S/c1-26-20-8-5-15-24(22(20)27)16-21(25)23-14-13-17-9-11-19(12-10-17)18-6-3-2-4-7-18/h2-12,15H,13-14,16H2,1H3,(H,23,25) DHHBMHIBSJVIFD-UHFFFAOYSA-N 50529328 CHEMBL4475441 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 17400 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529328&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155538090 440737910 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298870 CCCC[C@H](N)C(=O)NNc1cccc(c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H35N5O4/c1-2-3-15-26(32)30(38)36-35-24-13-9-12-22(17-24)29(37)34-28(31(39)40-20-21-10-5-4-6-11-21)18-23-19-33-27-16-8-7-14-25(23)27/h4-14,16-17,19,26,28,33,35H,2-3,15,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1 HSUTVEOJRBSEAV-XCZPVHLTSA-N 50529320 CHEMBL4540943 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4300 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529320&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155550629 440737902 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298871 CCCC[C@H](N)C(=O)NNc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H35N5O4/c1-2-3-12-26(32)30(38)36-35-24-16-14-22(15-17-24)29(37)34-28(31(39)40-20-21-9-5-4-6-10-21)18-23-19-33-27-13-8-7-11-25(23)27/h4-11,13-17,19,26,28,33,35H,2-3,12,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1 ZWCJCHLBYMDNAF-XCZPVHLTSA-N 50529330 CHEMBL4527760 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1200 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529330&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155545269 440737912 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298876 CC(C)[C@H](NC(=O)Cn1cccc(O)c1=O)C(=O)OCc1ccccc1 InChI=1S/C19H22N2O5/c1-13(2)17(19(25)26-12-14-7-4-3-5-8-14)20-16(23)11-21-10-6-9-15(22)18(21)24/h3-10,13,17,22H,11-12H2,1-2H3,(H,20,23)/t17-/m0/s1 HUSJMVGDLIDROU-KRWDZBQOSA-N 50529325 CHEMBL4436776 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8900 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529325&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155512116 440737907 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298877 CCCC[C@H](N)C(=O)NNc1cccc(c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H35N5O4/c1-2-3-15-26(32)30(38)36-35-24-13-9-12-22(17-24)29(37)34-28(31(39)40-20-21-10-5-4-6-11-21)18-23-19-33-27-16-8-7-14-25(23)27/h4-14,16-17,19,26,28,33,35H,2-3,15,18,20,32H2,1H3,(H,34,37)(H,36,38)/t26-,28-/m0/s1 HSUTVEOJRBSEAV-XCZPVHLTSA-N 50529320 CHEMBL4540943 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7900 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529320&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155550629 440737902 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298879 CC(C)[C@H](NC(=O)Cn1cccc(O)c1=O)C(=O)OCc1ccccc1 InChI=1S/C19H22N2O5/c1-13(2)17(19(25)26-12-14-7-4-3-5-8-14)20-16(23)11-21-10-6-9-15(22)18(21)24/h3-10,13,17,22H,11-12H2,1-2H3,(H,20,23)/t17-/m0/s1 HUSJMVGDLIDROU-KRWDZBQOSA-N 50529325 CHEMBL4436776 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4900 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529325&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155512116 440737907 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298882 Oc1cccn(CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)c1=O InChI=1S/C25H23N3O5/c29-22-11-6-12-28(24(22)31)15-23(30)27-21(25(32)33-16-17-7-2-1-3-8-17)13-18-14-26-20-10-5-4-9-19(18)20/h1-12,14,21,26,29H,13,15-16H2,(H,27,30)/t21-/m0/s1 PEFBFISDEVURKN-NRFANRHFSA-N 50529326 CHEMBL4557197 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 700 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529326&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155554600 440737908 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298886 Oc1cccn(CC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)c1=O InChI=1S/C25H23N3O5/c29-22-11-6-12-28(24(22)31)15-23(30)27-21(25(32)33-16-17-7-2-1-3-8-17)13-18-14-26-20-10-5-4-9-19(18)20/h1-12,14,21,26,29H,13,15-16H2,(H,27,30)/t21-/m0/s1 PEFBFISDEVURKN-NRFANRHFSA-N 50529326 CHEMBL4557197 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 10300 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529326&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155554600 440737908 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298889 OC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)Cn1cccc(O)c1=O InChI=1S/C18H17N3O5/c22-15-6-3-7-21(17(15)24)10-16(23)20-14(18(25)26)8-11-9-19-13-5-2-1-4-12(11)13/h1-7,9,14,19,22H,8,10H2,(H,20,23)(H,25,26)/t14-/m0/s1 GBAYREVXHGRLPG-AWEZNQCLSA-N 50529331 CHEMBL4535014 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 39300 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529331&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155547553 440737913 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298890 CCCC[C@H](N)C(=O)Nc1cc(ccn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C30H33N5O4/c1-2-3-12-24(31)29(37)35-27-17-21(14-15-32-27)28(36)34-26(30(38)39-19-20-9-5-4-6-10-20)16-22-18-33-25-13-8-7-11-23(22)25/h4-11,13-15,17-18,24,26,33H,2-3,12,16,19,31H2,1H3,(H,34,36)(H,32,35,37)/t24-,26-/m0/s1 VGHPVFACBOTLQP-AHWVRZQESA-N 50529322 CHEMBL4466281 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >10000 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529322&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155531602 440737904 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298894 Oc1cccn(CC(=O)NCCc2c[nH]c3ccccc23)c1=O InChI=1S/C17H17N3O3/c21-15-6-3-9-20(17(15)23)11-16(22)18-8-7-12-10-19-14-5-2-1-4-13(12)14/h1-6,9-10,19,21H,7-8,11H2,(H,18,22) NRCSONGNAATKNC-UHFFFAOYSA-N 50529327 CHEMBL4455738 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 17700 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529327&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search K0Q 6RD0 145925583 440737909 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51298895 CCCC[C@H](N)C(=O)Nc1ccc(cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H34N4O4/c1-2-3-12-26(32)30(37)34-24-16-14-22(15-17-24)29(36)35-28(31(38)39-20-21-9-5-4-6-10-21)18-23-19-33-27-13-8-7-11-25(23)27/h4-11,13-17,19,26,28,33H,2-3,12,18,20,32H2,1H3,(H,34,37)(H,35,36)/t26-,28-/m0/s1 YNBUILPSIRWOEF-XCZPVHLTSA-N 50529321 CHEMBL4575946 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4800 ChEMBL 10.1016/j.bmc.2019.115177 10.7270/Q2FN19NT 31711716 Tsoukalidou, S; Kakou, M; Mavridis, I; Koumantou, D; Calderone, V; Fragai, M; Stratikos, E; Papakyriakou, A; Vourloumis, D National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50529321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50529321&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 155564248 440737903 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51344609 CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O InChI=1S/C40H54N8O8/c1-5-24(4)34(47-35(50)29(44-37(52)33(41)23(2)3)18-26-13-15-28(49)16-14-26)38(53)45-30(20-27-21-42-22-43-27)39(54)48-17-9-12-32(48)36(51)46-31(40(55)56)19-25-10-7-6-8-11-25/h6-8,10-11,13-16,21-24,29-34,49H,5,9,12,17-20,41H2,1-4H3,(H,42,43)(H,44,52)(H,45,53)(H,46,51)(H,47,50)(H,55,56)/t24-,29-,30-,31-,32-,33-,34-/m0/s1 QSBGWDDCOJYQGY-KOQODJNWSA-N 85550 Ang IV::CAS_12676-15-2::CHEMBL261120::cid_123814 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7943 ChEMBL 10.1021/acsmedchemlett.0c00172 10.7270/Q2WM1J0W 32676150 Mpakali, A; Saridakis, E; Giastas, P; Maben, Z; Stern, LJ; Larhed, M; Hallberg, M; Stratikos, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85550&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 123814 136351650 CHEMBL261120 ZINC85545908 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51344612 N[C@H]1CCSSC[C@H](NC(=O)C[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)NCc1ccccc1CC(O)=O InChI=1S/C26H32N4O6S2/c27-21-9-10-37-38-15-22(26(36)28-14-18-4-2-1-3-17(18)12-24(33)34)30-23(32)13-19(29-25(21)35)11-16-5-7-20(31)8-6-16/h1-8,19,21-22,31H,9-15,27H2,(H,28,36)(H,29,35)(H,30,32)(H,33,34)/t19-,21-,22-/m0/s1 VZYRMNZEFCZSER-BVSLBCMMSA-N 50331042 2-(2-(((4R,8S,11S)-11-amino-8-(4-hydroxybenzyl)-6,10-dioxo-1,2-dithia-5,9-diazacyclotridecane-4-carboxamido)methyl)phenyl)acetic acid::CHEMBL1277623 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1259 ChEMBL 10.1021/acsmedchemlett.0c00172 10.7270/Q2WM1J0W 32676150 Mpakali, A; Saridakis, E; Giastas, P; Maben, Z; Stern, LJ; Larhed, M; Hallberg, M; Stratikos, E National Center for Scientific Research Demokritos http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50331042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50331042&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search ONN 6YDX 49840774 123110157 CHEMBL1277623 ZINC64447539 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411148 CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)c1ccc(cc1)N(CCN1CCCC1)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H32FN3O5S/c1-31(27(29(35)36)21-22-7-3-2-4-8-22)28(34)23-9-13-25(14-10-23)33(20-19-32-17-5-6-18-32)39(37,38)26-15-11-24(30)12-16-26/h2-4,7-16,27H,5-6,17-21H2,1H3,(H,35,36)/t27-/m0/s1 SESRJRLBHQWLSW-MHZLTWQESA-N 50570140 CHEMBL4863321 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 98000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570140&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164621671 471060285 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411149 CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)c1ccc(cc1)N(CCc1ccccc1)S(=O)(=O)c1ccccc1 InChI=1S/C31H30N2O5S/c1-32(29(31(35)36)23-25-13-7-3-8-14-25)30(34)26-17-19-27(20-18-26)33(22-21-24-11-5-2-6-12-24)39(37,38)28-15-9-4-10-16-28/h2-20,29H,21-23H2,1H3,(H,35,36)/t29-/m0/s1 HLASIBRBPBFFOG-LJAQVGFWSA-N 50570141 CHEMBL4875775 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 89000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570141&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164625950 471060286 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411150 OC(=O)CN(CC(=O)N1CCN(Cc2ccccc2)C[C@@H]1Cc1c[nH]c2ccccc12)c1ccccc1 50570142 CHEMBL4878060 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 22000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570142&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164626231 471060287 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411151 CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)c1ccc(cc1)N(CCN1CCCC1)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C29H32FN3O5S/c1-31(27(29(35)36)21-22-7-3-2-4-8-22)28(34)23-9-13-25(14-10-23)33(20-19-32-17-5-6-18-32)39(37,38)26-15-11-24(30)12-16-26/h2-4,7-16,27H,5-6,17-21H2,1H3,(H,35,36)/t27-/m0/s1 SESRJRLBHQWLSW-MHZLTWQESA-N 50570140 CHEMBL4863321 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 9700 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570140&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164621671 471060285 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411152 CN([C@@H](Cc1ccccc1)C(O)=O)C(=O)c1ccc(cc1)N(CCCN1CCCC1)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C30H34FN3O5S/c1-32(28(30(36)37)22-23-8-3-2-4-9-23)29(35)24-10-14-26(15-11-24)34(21-7-20-33-18-5-6-19-33)40(38,39)27-16-12-25(31)13-17-27/h2-4,8-17,28H,5-7,18-22H2,1H3,(H,36,37)/t28-/m0/s1 XEACBHPVJFFRBP-NDEPHWFRSA-N 50570143 CHEMBL4853168 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 100000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570143&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164613431 471060288 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411153 OC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(cc1)N(CCN1CCCC1)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C28H30FN3O5S/c29-23-10-14-25(15-11-23)38(36,37)32(19-18-31-16-4-5-17-31)24-12-8-22(9-13-24)27(33)30-26(28(34)35)20-21-6-2-1-3-7-21/h1-3,6-15,26H,4-5,16-20H2,(H,30,33)(H,34,35)/t26-/m0/s1 KWUAUZSXVLNUAM-SANMLTNESA-N 50570144 CHEMBL4849358 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 100000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570144&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164617247 471060289 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411155 CCCC[C@H](N)C(=O)Nc1ccc(cc1N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)OC InChI=1S/C23H30N4O5/c1-3-4-5-17(24)22(30)26-19-11-8-15(13-18(19)25)21(29)27-20(23(31)32-2)12-14-6-9-16(28)10-7-14/h6-11,13,17,20,28H,3-5,12,24-25H2,1-2H3,(H,26,30)(H,27,29)/t17-,20-/m0/s1 RXZHGXBRKJGXMY-PXNSSMCTSA-N 50077017 CHEMBL3416725 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077017&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 118734292 313073382 CHEMBL3416725 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411156 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 755000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51411157 N[C@@H](CCc1ccccc1)P(O)(=O)C[C@@H](CC#C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O InChI=1S/C24H30N3O4P/c1-2-9-20(17-32(30,31)22(25)15-14-18-10-5-3-6-11-18)24(29)27-21(23(26)28)16-19-12-7-4-8-13-19/h1,3-8,10-13,20-22H,9,14-17,25H2,(H2,26,28)(H,27,29)(H,30,31)/t20-,21+,22-/m1/s1 QCPJTEUURKCRNT-BHIFYINESA-N 50245396 CHEMBL4101200 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 33000 ChEMBL 10.1016/j.ejmech.2020.113053 10.7270/Q29Z98PR 33359953 Laura, M; Ronan, G; Vy, LB; Valentin, G; Omar, CA; Virgyl, C; Piveteau, C; Melissa, R; Charlotte, F; Sandrine, W; Julie, C; Julie, DR; Damien, B; Florence, L; Peter, VE; Benoit, D; Rebecca, DP Institut Pasteur de Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50245396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50245396&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 137660529 386403419 CHEMBL4101200 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413159 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2951 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413160 CC(C)C[C@@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50570847 CHEMBL4863168 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 97724 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570847&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164625468 471060992 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413161 CC(C)C[C@H](CP(O)(=O)[C@H](CCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50570848 CHEMBL4872604 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <218776 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570848&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164623073 471060993 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413162 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CP(O)(=O)[C@@H](N)CCc1ccccc1 50570849 CHEMBL4854733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 891 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570849&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164612947 471060994 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413163 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O 50570850 CHEMBL4877339 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2344 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570850&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164626012 471060995 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413164 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)NCCc1c[nH]c2ccccc12 50570851 CHEMBL4853049 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1259 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570851&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164617898 471060996 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413165 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3000 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413166 CC(C)C[C@@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50570847 CHEMBL4863168 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 98000 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570847&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164625468 471060992 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413167 CC(C)C[C@H](CP(O)(=O)[C@H](CCc1ccccc1)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50570848 CHEMBL4872604 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >220000 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570848&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164623073 471060993 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413168 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CP(O)(=O)[C@@H](N)CCc1ccccc1 50570849 CHEMBL4854733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 900 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570849&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164612947 471060994 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413169 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O 50570850 CHEMBL4877339 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2400 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570850&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164626012 471060995 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413170 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)NCCc1c[nH]c2ccccc12 50570851 CHEMBL4853049 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1300 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570851&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164617898 471060996 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51413172 CC(C)C[C@H](CP(O)(=O)[C@@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O 50076744 CHEMBL3416733 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11 ChEMBL 10.1016/j.bmcl.2021.128050 10.7270/Q2445R98 33887439 Wilding, B; Pasqua, AE; E A Chessum, N; Pierrat, OA; Hahner, T; Tomlin, K; Shehu, E; Burke, R; Richards, GM; Whitton, B; Arwert, EN; Thapaliya, A; Salimraj, R; van Montfort, R; Skawinska, A; Hayes, A; Raynaud, F; Chopra, R; Jones, K; Newton, G; Cheeseman, MD The Institute of Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50076744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50076744&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search P52 6M8P,4JBS 72193911 313073373 CHEMBL3416733 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415705 CCC(C)(NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1)C(O)=O InChI=1S/C20H17ClFNO4/c1-3-20(2,19(25)26)23-18(24)15-10-14(22)8-12-9-16(27-17(12)15)11-4-6-13(21)7-5-11/h4-10H,3H2,1-2H3,(H,23,24)(H,25,26) ATBPUXQNMPYSAT-UHFFFAOYSA-N 50571856 CHEMBL4850551 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571856&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164614991 471062001 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415706 CC(C)(NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1)C(O)=O InChI=1S/C19H15ClFNO4/c1-19(2,18(24)25)22-17(23)14-9-13(21)7-11-8-15(26-16(11)14)10-3-5-12(20)6-4-10/h3-9H,1-2H3,(H,22,23)(H,24,25) MNGHEAPDIWGAHE-UHFFFAOYSA-N 50571857 CHEMBL4854083 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571857&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164615114 471062002 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415707 OC(=O)C1(CC1)NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C19H13ClFNO4/c20-12-3-1-10(2-4-12)15-8-11-7-13(21)9-14(16(11)26-15)17(23)22-19(5-6-19)18(24)25/h1-4,7-9H,5-6H2,(H,22,23)(H,24,25) IDQHOHSXXCXYJU-UHFFFAOYSA-N 50571864 CHEMBL4853997 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571864&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164616865 471062009 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415708 OC(=O)C1(CCCC1)NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C21H17ClFNO4/c22-14-5-3-12(4-6-14)17-10-13-9-15(23)11-16(18(13)28-17)19(25)24-21(20(26)27)7-1-2-8-21/h3-6,9-11H,1-2,7-8H2,(H,24,25)(H,26,27) GIWMBCHTAJIGDG-UHFFFAOYSA-N 50571865 CHEMBL4863142 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571865&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164624870 471062010 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415709 OC(=O)C1(CCCCC1)NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C22H19ClFNO4/c23-15-6-4-13(5-7-15)18-11-14-10-16(24)12-17(19(14)29-18)20(26)25-22(21(27)28)8-2-1-3-9-22/h4-7,10-12H,1-3,8-9H2,(H,25,26)(H,27,28) QYWJJEUPNXQBKA-UHFFFAOYSA-N 50571866 CHEMBL4862557 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571866&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164620813 471062011 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415710 OC(=O)C1(Cc2ccccc2C1)NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C25H17ClFNO4/c26-18-7-5-14(6-8-18)21-10-17-9-19(27)11-20(22(17)32-21)23(29)28-25(24(30)31)12-15-3-1-2-4-16(15)13-25/h1-11H,12-13H2,(H,28,29)(H,30,31) CKFVSFXLFRDJNT-UHFFFAOYSA-N 50571867 CHEMBL4875461 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571867&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164627922 471062012 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415711 OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C24H17ClFNO4/c25-17-8-6-15(7-9-17)21-12-16-11-18(26)13-19(22(16)31-21)23(28)27-20(24(29)30)10-14-4-2-1-3-5-14/h1-9,11-13,20H,10H2,(H,27,28)(H,29,30)/t20-/m1/s1 MIUAQLGAIXHIPR-HXUWFJFHSA-N 50571868 CHEMBL4854530 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571868&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164613476 471062013 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415712 OC(=O)[C@H](Cc1ccccc1)NC(=O)c1cc(F)cc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C24H17ClFNO4/c25-17-8-6-15(7-9-17)21-12-16-11-18(26)13-19(22(16)31-21)23(28)27-20(24(29)30)10-14-4-2-1-3-5-14/h1-9,11-13,20H,10H2,(H,27,28)(H,29,30)/t20-/m0/s1 MIUAQLGAIXHIPR-FQEVSTJZSA-N 50571869 CHEMBL4852033 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571869&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164613945 471062014 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415713 CC(C)(NC(=O)c1cccc2cc(oc12)-c1ccc(Cl)cc1)C(O)=O InChI=1S/C19H16ClNO4/c1-19(2,18(23)24)21-17(22)14-5-3-4-12-10-15(25-16(12)14)11-6-8-13(20)9-7-11/h3-10H,1-2H3,(H,21,22)(H,23,24) FQLGBJGWLCBOOO-UHFFFAOYSA-N 50571871 CHEMBL4873254 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571871&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164623577 471062016 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415714 OC(=O)C1(CCCCC1)NC(=O)c1cccc2cc(oc12)-c1ccc(Cl)cc1 InChI=1S/C22H20ClNO4/c23-16-9-7-14(8-10-16)18-13-15-5-4-6-17(19(15)28-18)20(25)24-22(21(26)27)11-2-1-3-12-22/h4-10,13H,1-3,11-12H2,(H,24,25)(H,26,27) CAZIGEHCBGMUHD-UHFFFAOYSA-N 50571872 CHEMBL4864508 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571872&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164622208 471062017 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415715 CC(C)(NC(=O)c1cccc2c(Br)c(oc12)-c1ccc(Cl)cc1)C(O)=O InChI=1S/C19H15BrClNO4/c1-19(2,18(24)25)22-17(23)13-5-3-4-12-14(20)15(26-16(12)13)10-6-8-11(21)9-7-10/h3-9H,1-2H3,(H,22,23)(H,24,25) RDBVPPRJXSFHKM-UHFFFAOYSA-N 50571873 CHEMBL4877678 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571873&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164627073 471062018 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51415716 OC(=O)C1(CCCCC1)NC(=O)c1cccc2c(Br)c(oc12)-c1ccc(Cl)cc1 InChI=1S/C22H19BrClNO4/c23-17-15-5-4-6-16(19(15)29-18(17)13-7-9-14(24)10-8-13)20(26)25-22(21(27)28)11-2-1-3-12-22/h4-10H,1-3,11-12H2,(H,25,26)(H,27,28) JXOQWYLAVQAJFL-UHFFFAOYSA-N 50571874 CHEMBL4855038 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >30000 ChEMBL 10.1021/acsmedchemlett.1c00235 10.7270/Q2QJ7N22 34267884 Deddouche-Grass, S; Andouche, C; Bärenz, F; Halter, C; Hohwald, A; Lebrun, L; Membré, N; Morales, R; Muzet, N; Poirot, M; Reynaud, M; Roujean, V; Weber, F; Zimmermann, A; Heng, R; Basse, N Sanofi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571874&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 164616314 471062019 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491323 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C35H42N4O5/c1-23(2)19-30(38-34(42)32(40)28(36)18-17-24-11-5-3-6-12-24)33(41)39-31(35(43)44-22-25-13-7-4-8-14-25)20-26-21-37-29-16-10-9-15-27(26)29/h3-16,21,23,28,30-32,37,40H,17-20,22,36H2,1-2H3,(H,38,42)(H,39,41)/t28-,30+,31+,32+/m1/s1 LVSXCZWZQIYCSO-DNUNIWOASA-N 50601025 CHEMBL5207828 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1700 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601025&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168297030 482611877 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491324 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C28H36N4O5/c1-17(2)14-23(31-27(35)25(33)21(29)13-12-18-8-4-3-5-9-18)26(34)32-24(28(36)37)15-19-16-30-22-11-7-6-10-20(19)22/h3-11,16-17,21,23-25,30,33H,12-15,29H2,1-2H3,(H,31,35)(H,32,34)(H,36,37)/t21-,23+,24+,25+/m1/s1 ULZGIJQWFIUBKB-VZVHPENPSA-N 50601026 CHEMBL5202569 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 17000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601026&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168292702 482611878 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491325 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C28H36N4O6/c1-17(2)12-23(31-27(36)25(34)21(29)15-33)26(35)32-24(28(37)38-16-18-8-4-3-5-9-18)13-19-14-30-22-11-7-6-10-20(19)22/h3-11,14,17,21,23-25,30,33-34H,12-13,15-16,29H2,1-2H3,(H,31,36)(H,32,35)/t21-,23+,24+,25+/m1/s1 DYGKQTMULZFMLM-VZVHPENPSA-N 50601027 CHEMBL5196425 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 11000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601027&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168285152 482611879 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491326 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C29H38N4O6/c1-18(2)14-24(32-28(37)26(35)22(30)12-13-34)27(36)33-25(29(38)39-17-19-8-4-3-5-9-19)15-20-16-31-23-11-7-6-10-21(20)23/h3-11,16,18,22,24-26,31,34-35H,12-15,17,30H2,1-2H3,(H,32,37)(H,33,36)/t22-,24+,25+,26+/m1/s1 LDJAILYVFVKDFA-DNZIZEQUSA-N 50601028 CHEMBL5174528 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 30000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601028&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168275315 482611880 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491327 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCCCO InChI=1S/C23H37N3O7/c1-14(2)12-18(25-22(31)20(29)17(24)6-4-5-11-27)21(30)26-19(23(32)33-3)13-15-7-9-16(28)10-8-15/h7-10,14,17-20,27-29H,4-6,11-13,24H2,1-3H3,(H,25,31)(H,26,30)/t17-,18+,19+,20+/m1/s1 LCFWQIPNOMDXPJ-FYQPLNBISA-N 50601029 CHEMBL5194823 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 4900 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601029&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search I88 164575516 482611881 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491328 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(OCc2ccccc2)cc1 InChI=1S/C34H43N3O8/c1-22(2)19-29(32(40)37-30(34(42)43-3)20-23-9-11-25(38)12-10-23)36-33(41)31(39)28(35)17-18-44-26-13-15-27(16-14-26)45-21-24-7-5-4-6-8-24/h4-16,22,28-31,38-39H,17-21,35H2,1-3H3,(H,36,41)(H,37,40)/t28-,29+,30+,31+/m1/s1 VXWHBSKDVGKARU-BHSUFKTOSA-N 50601030 CHEMBL5185614 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7500 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601030&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168282634 482611882 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491329 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C42H48N4O7/c1-28(2)23-37(45-41(49)39(47)35(43)21-22-51-32-17-19-33(20-18-32)52-26-29-11-5-3-6-12-29)40(48)46-38(42(50)53-27-30-13-7-4-8-14-30)24-31-25-44-36-16-10-9-15-34(31)36/h3-20,25,28,35,37-39,44,47H,21-24,26-27,43H2,1-2H3,(H,45,49)(H,46,48)/t35-,37+,38+,39+/m1/s1 NSNUEFGGCSNMHU-XWINOZFQSA-N 50601031 CHEMBL5199194 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 5500 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601031&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168291750 482611883 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491330 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(O)cc1 InChI=1S/C27H37N3O8/c1-16(2)14-22(25(34)30-23(27(36)37-3)15-17-4-6-18(31)7-5-17)29-26(35)24(33)21(28)12-13-38-20-10-8-19(32)9-11-20/h4-11,16,21-24,31-33H,12-15,28H2,1-3H3,(H,29,35)(H,30,34)/t21-,22+,23+,24+/m1/s1 PBYNWRKJSAGRFG-SBFWRKJZSA-N 50601032 CHEMBL5183817 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2300 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601032&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168281713 482611884 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491331 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(O)cc1 InChI=1S/C29H38N4O7/c1-17(2)14-24(32-28(37)26(35)22(30)12-13-40-20-10-8-19(34)9-11-20)27(36)33-25(29(38)39-3)15-18-16-31-23-7-5-4-6-21(18)23/h4-11,16-17,22,24-26,31,34-35H,12-15,30H2,1-3H3,(H,32,37)(H,33,36)/t22-,24+,25+,26+/m1/s1 ZPHQKYQWQLYSDS-DNZIZEQUSA-N 50601033 CHEMBL5209483 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 580 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601033&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168296154 482611885 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491332 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)COc1ccc(O)cc1 InChI=1S/C28H36N4O7/c1-16(2)12-23(31-27(36)25(34)21(29)15-39-19-10-8-18(33)9-11-19)26(35)32-24(28(37)38-3)13-17-14-30-22-7-5-4-6-20(17)22/h4-11,14,16,21,23-25,30,33-34H,12-13,15,29H2,1-3H3,(H,31,36)(H,32,35)/t21-,23+,24+,25+/m1/s1 WXYVFLSKRTUFAE-VZVHPENPSA-N 50601034 CHEMBL5191661 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 760 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601034&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search KFR 164513565 482611886 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491333 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1ccc(O)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C28H36N4O7/c1-16(2)13-23(31-27(36)25(34)21(29)11-12-39-19-9-7-18(33)8-10-19)26(35)32-24(28(37)38)14-17-15-30-22-6-4-3-5-20(17)22/h3-10,15-16,21,23-25,30,33-34H,11-14,29H2,1-2H3,(H,31,36)(H,32,35)(H,37,38)/t21-,23+,24+,25+/m1/s1 CYJAZIKQEIQCOG-VZVHPENPSA-N 50601035 CHEMBL5194003 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 2000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601035&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168288367 482611887 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491334 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(O)c1 InChI=1S/C27H37N3O8/c1-16(2)13-22(25(34)30-23(27(36)37-3)14-17-7-9-18(31)10-8-17)29-26(35)24(33)21(28)11-12-38-20-6-4-5-19(32)15-20/h4-10,15-16,21-24,31-33H,11-14,28H2,1-3H3,(H,29,35)(H,30,34)/t21-,22+,23+,24+/m1/s1 ITLJOJDZTQMFQG-SBFWRKJZSA-N 50601036 CHEMBL5184077 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601036&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168280572 482611888 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491335 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(O)c1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C28H36N4O7/c1-16(2)12-23(31-27(36)25(34)21(29)10-11-39-19-7-5-6-18(33)14-19)26(35)32-24(28(37)38)13-17-15-30-22-9-4-3-8-20(17)22/h3-9,14-16,21,23-25,30,33-34H,10-13,29H2,1-2H3,(H,31,36)(H,32,35)(H,37,38)/t21-,23+,24+,25+/m1/s1 MNIKFLYSPBYGSY-VZVHPENPSA-N 50601037 CHEMBL5200376 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1600 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601037&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168292370 482611889 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491336 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1ccccc1O InChI=1S/C27H37N3O8/c1-16(2)14-20(25(34)30-21(27(36)37-3)15-17-8-10-18(31)11-9-17)29-26(35)24(33)19(28)12-13-38-23-7-5-4-6-22(23)32/h4-11,16,19-21,24,31-33H,12-15,28H2,1-3H3,(H,29,35)(H,30,34)/t19-,20+,21+,24+/m1/s1 BIDCKWXDZHBBDY-XBJMDHIQSA-N 50601038 CHEMBL5204566 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1800 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601038&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168295299 482611890 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491337 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCOc1ccccc1O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C28H36N4O7/c1-16(2)13-21(31-27(36)25(34)19(29)11-12-39-24-10-6-5-9-23(24)33)26(35)32-22(28(37)38)14-17-15-30-20-8-4-3-7-18(17)20/h3-10,15-16,19,21-22,25,30,33-34H,11-14,29H2,1-2H3,(H,31,36)(H,32,35)(H,37,38)/t19-,21+,22+,25+/m1/s1 PQYPBOWQWFVVJD-AXJZPPOTSA-N 50601039 CHEMBL5173865 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1900 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601039&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168271540 482611891 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491338 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(Cl)c1 InChI=1S/C29H37ClN4O6/c1-17(2)13-24(33-28(37)26(35)22(31)11-12-40-20-8-6-7-19(30)15-20)27(36)34-25(29(38)39-3)14-18-16-32-23-10-5-4-9-21(18)23/h4-10,15-17,22,24-26,32,35H,11-14,31H2,1-3H3,(H,33,37)(H,34,36)/t22-,24+,25+,26+/m1/s1 QELONQVCEFPRGM-DNZIZEQUSA-N 50601040 CHEMBL5195928 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 460 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601040&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168284738 482611892 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491339 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCOc1cccc(Cl)c1 InChI=1S/C27H36ClN3O7/c1-16(2)13-22(25(34)31-23(27(36)37-3)14-17-7-9-19(32)10-8-17)30-26(35)24(33)21(29)11-12-38-20-6-4-5-18(28)15-20/h4-10,15-16,21-24,32-33H,11-14,29H2,1-3H3,(H,30,35)(H,31,34)/t21-,22+,23+,24+/m1/s1 YHYCZFIGZSESIE-SBFWRKJZSA-N 50601041 CHEMBL5197001 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 580 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601041&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168285580 482611893 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491340 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)COc1cc(F)c(F)c(F)c1 InChI=1S/C28H33F3N4O6/c1-14(2)8-22(34-27(38)25(36)20(32)13-41-16-10-18(29)24(31)19(30)11-16)26(37)35-23(28(39)40-3)9-15-12-33-21-7-5-4-6-17(15)21/h4-7,10-12,14,20,22-23,25,33,36H,8-9,13,32H2,1-3H3,(H,34,38)(H,35,37)/t20-,22+,23+,25+/m1/s1 ZGOYLLCQBCBXHF-GIQJJWITSA-N 50601042 CHEMBL5195885 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 250 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601042&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168292493 482611894 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491341 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C30H38N4O7/c1-18(2)14-24(33-29(39)27(37)22(31)12-13-26(35)36)28(38)34-25(30(40)41-17-19-8-4-3-5-9-19)15-20-16-32-23-11-7-6-10-21(20)23/h3-11,16,18,22,24-25,27,32,37H,12-15,17,31H2,1-2H3,(H,33,39)(H,34,38)(H,35,36)/t22-,24+,25+,27+/m1/s1 FMYLPALWYNDFHN-TXKDVJNZSA-N 50601043 CHEMBL5177041 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 13000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601043&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168278160 482611895 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491342 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C23H32N4O7/c1-12(2)9-17(26-22(32)20(30)15(24)7-8-19(28)29)21(31)27-18(23(33)34)10-13-11-25-16-6-4-3-5-14(13)16/h3-6,11-12,15,17-18,20,25,30H,7-10,24H2,1-2H3,(H,26,32)(H,27,31)(H,28,29)(H,33,34)/t15-,17+,18+,20+/m1/s1 SQLMZUVREWIOLY-HYJFEMIMSA-N 50601047 CHEMBL5194052 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 19000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601047&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168285380 482611899 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491343 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCCC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 InChI=1S/C31H40N4O7/c1-19(2)15-25(34-30(40)28(38)23(32)12-8-14-27(36)37)29(39)35-26(31(41)42-18-20-9-4-3-5-10-20)16-21-17-33-24-13-7-6-11-22(21)24/h3-7,9-11,13,17,19,23,25-26,28,33,38H,8,12,14-16,18,32H2,1-2H3,(H,34,40)(H,35,39)(H,36,37)/t23-,25+,26+,28+/m1/s1 RKUGLBWIDGRJLB-XAUNCYBDSA-N 50601044 CHEMBL5194478 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 31000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601044&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168288864 482611896 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491344 COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCCC(O)=O InChI=1S/C23H35N3O8/c1-13(2)11-17(25-22(32)20(30)16(24)5-4-6-19(28)29)21(31)26-18(23(33)34-3)12-14-7-9-15(27)10-8-14/h7-10,13,16-18,20,27,30H,4-6,11-12,24H2,1-3H3,(H,25,32)(H,26,31)(H,28,29)/t16-,17+,18+,20+/m1/s1 ZBXSBMCHIRXXKX-LXZJYRNTSA-N 50601048 CHEMBL5196999 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 13000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601048&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168285579 482611900 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491345 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CC(=O)NCCO InChI=1S/C25H37N5O7/c1-14(2)10-19(29-24(35)22(33)17(26)12-21(32)27-8-9-31)23(34)30-20(25(36)37-3)11-15-13-28-18-7-5-4-6-16(15)18/h4-7,13-14,17,19-20,22,28,31,33H,8-12,26H2,1-3H3,(H,27,32)(H,29,35)(H,30,34)/t17-,19+,20+,22+/m1/s1 AZUHLLUJTZMKMH-XBZUYWNMSA-N 50601049 CHEMBL5181510 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 30000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601049&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168277228 482611901 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491346 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CNCCO InChI=1S/C24H37N5O6/c1-14(2)10-19(28-23(33)21(31)17(25)13-26-8-9-30)22(32)29-20(24(34)35-3)11-15-12-27-18-7-5-4-6-16(15)18/h4-7,12,14,17,19-21,26-27,30-31H,8-11,13,25H2,1-3H3,(H,28,33)(H,29,32)/t17-,19+,20+,21+/m1/s1 XDPZIFKCURPXCJ-HZEGPAAWSA-N 50601051 CHEMBL5199630 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 18000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601051&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168290974 482611903 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491347 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CNC(CO)CO InChI=1S/C25H39N5O7/c1-14(2)8-20(29-24(35)22(33)18(26)11-27-16(12-31)13-32)23(34)30-21(25(36)37-3)9-15-10-28-19-7-5-4-6-17(15)19/h4-7,10,14,16,18,20-22,27-28,31-33H,8-9,11-13,26H2,1-3H3,(H,29,35)(H,30,34)/t18-,20+,21+,22+/m1/s1 ZLTMYYQEAJDPSU-GBAJDQEWSA-N 50601052 CHEMBL5203985 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 27000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601052&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168293709 482611904 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491348 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCNCCC(O)=O InChI=1S/C26H39N5O7/c1-15(2)12-20(30-25(36)23(34)18(27)8-10-28-11-9-22(32)33)24(35)31-21(26(37)38-3)13-16-14-29-19-7-5-4-6-17(16)19/h4-7,14-15,18,20-21,23,28-29,34H,8-13,27H2,1-3H3,(H,30,36)(H,31,35)(H,32,33)/t18-,20+,21+,23+/m1/s1 MKKYXMZTDFKYBR-ANZJIFDASA-N 50601053 CHEMBL5191937 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 8200 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601053&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168285307 482611905 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491349 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCNC(CO)CO InChI=1S/C26H41N5O7/c1-15(2)10-21(30-25(36)23(34)19(27)8-9-28-17(13-32)14-33)24(35)31-22(26(37)38-3)11-16-12-29-20-7-5-4-6-18(16)20/h4-7,12,15,17,19,21-23,28-29,32-34H,8-11,13-14,27H2,1-3H3,(H,30,36)(H,31,35)/t19-,21+,22+,23+/m1/s1 KPRHLZJHLVAMAH-SWUCNREESA-N 50601054 CHEMBL5178792 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 9600 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601054&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168273765 482611906 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491350 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCNCCO InChI=1S/C25H39N5O6/c1-15(2)12-20(29-24(34)22(32)18(26)8-9-27-10-11-31)23(33)30-21(25(35)36-3)13-16-14-28-19-7-5-4-6-17(16)19/h4-7,14-15,18,20-22,27-28,31-32H,8-13,26H2,1-3H3,(H,29,34)(H,30,33)/t18-,20+,21+,22+/m1/s1 DJZGVKQMRVQDPK-GBAJDQEWSA-N 50601055 CHEMBL5182525 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 3800 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601055&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168282473 482611907 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491351 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCN(C)CCO InChI=1S/C26H41N5O6/c1-16(2)13-21(29-25(35)23(33)19(27)9-10-31(3)11-12-32)24(34)30-22(26(36)37-4)14-17-15-28-20-8-6-5-7-18(17)20/h5-8,15-16,19,21-23,28,32-33H,9-14,27H2,1-4H3,(H,29,35)(H,30,34)/t19-,21+,22+,23+/m1/s1 GRWAJSJPXWWVLF-SWUCNREESA-N 50601056 CHEMBL5189714 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 13000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601056&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168283208 482611908 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491352 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CN[C@@H](Cc1ccc(O)cc1)C(=O)OC InChI=1S/C32H43N5O8/c1-18(2)13-25(29(40)37-27(32(43)45-4)15-20-16-34-24-8-6-5-7-22(20)24)36-30(41)28(39)23(33)17-35-26(31(42)44-3)14-19-9-11-21(38)12-10-19/h5-12,16,18,23,25-28,34-35,38-39H,13-15,17,33H2,1-4H3,(H,36,41)(H,37,40)/t23-,25+,26+,27+,28+/m1/s1 ZUBRZDDOAVYLJY-OFGRGEMESA-N 50601045 CHEMBL5209535 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 1600 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601045&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168297105 482611897 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491353 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCN[C@@H](Cc1ccc(O)cc1)C(=O)OC InChI=1S/C33H45N5O8/c1-19(2)15-26(30(41)38-28(33(44)46-4)17-21-18-36-25-8-6-5-7-23(21)25)37-31(42)29(40)24(34)13-14-35-27(32(43)45-3)16-20-9-11-22(39)12-10-20/h5-12,18-19,24,26-29,35-36,39-40H,13-17,34H2,1-4H3,(H,37,42)(H,38,41)/t24-,26+,27+,28+,29+/m1/s1 COMBCDCRFAXRAT-QDXQZTBOSA-N 50601057 CHEMBL5171198 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 7900 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601057&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168269001 482611909 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491354 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCN[C@@H](Cc1ccc(O)cc1)C(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C31H41N5O8/c1-17(2)13-24(28(39)36-26(31(43)44)15-19-16-34-23-6-4-3-5-21(19)23)35-29(40)27(38)22(32)11-12-33-25(30(41)42)14-18-7-9-20(37)10-8-18/h3-10,16-17,22,24-27,33-34,37-38H,11-15,32H2,1-2H3,(H,35,40)(H,36,39)(H,41,42)(H,43,44)/t22-,24+,25+,26+,27+/m1/s1 ZILOINZZGFDOLE-AMNZSHNSSA-N 50601058 CHEMBL5199907 Endoplasmic reticulum aminopeptidase 2 Homo sapiens 37000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601058&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168290348 482611910 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491355 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1 VGGGPCQERPFHOB-RDBSUJKOSA-N 23971 (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid::Bestatin::CHEMBL29292::Ubenimex Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23971&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search BES 4RUH,2XQ0,4GAA,5NTD,1XRY,2YD0,2HPT,4XMX,4ZLA,1TXR,3EBH,1HS6,3H8G,3MDJ,4KXB,1GW6,3FTX,3KR4,3FUE,3FUH,3FUF,4FKK,5IB9,4FYR,2DQM,2EK9,2ZOG,2ZOF 72172 53785971 CHEMBL29292 ZINC01542895 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491356 COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CCc1ccccc1 InChI=1S/C18H28N2O4/c1-12(2)11-15(18(23)24-3)20-17(22)16(21)14(19)10-9-13-7-5-4-6-8-13/h4-8,12,14-16,21H,9-11,19H2,1-3H3,(H,20,22)/t14-,15+,16+/m1/s1 UGQHQMRKUBNIKT-PMPSAXMXSA-N 50601046 CHEMBL5172109 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601046&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168270935 482611898 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491357 CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CCc1ccccc1)C(O)=O InChI=1S/C17H26N2O4/c1-11(2)10-14(17(22)23)19-16(21)15(20)13(18)9-8-12-6-4-3-5-7-12/h3-7,11,13-15,20H,8-10,18H2,1-2H3,(H,19,21)(H,22,23)/t13-,14+,15+/m1/s1 WINMLZWYPTWRES-ILXRZTDVSA-N 50601024 CHEMBL5185171 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601024&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168278557 482611876 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 51491358 COC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](O)[C@H](N)CC(=O)NC(CO)CO InChI=1S/C26H39N5O8/c1-14(2)8-20(30-25(37)23(35)18(27)10-22(34)29-16(12-32)13-33)24(36)31-21(26(38)39-3)9-15-11-28-19-7-5-4-6-17(15)19/h4-7,11,14,16,18,20-21,23,28,32-33,35H,8-10,12-13,27H2,1-3H3,(H,29,34)(H,30,37)(H,31,36)/t18-,20+,21+,23+/m1/s1 BFWHTLSVKCBXCS-ANZJIFDASA-N 50601050 CHEMBL5177621 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >100000 ChEMBL 10.7270/Q2222ZVG 35833347 Vourloumis, D; Mavridis, I; Athanasoulis, A; Temponeras, I; Koumantou, D; Giastas, P; Mpakali, A; Magrioti, V; Leib, J; van Endert, P; Stratikos, E; Papakyriakou, A National Centre for Scientific Research "Demokritos" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50601050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50601050&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 168276621 482611902 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391977 ONC(=O)[C@@H](Cc1c[nH]c2ccccc12)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 661055 (R)-N-hydroxy-3-(1H-indol-3-yl)-2-(4-((5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 2 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661055&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391978 ONC(=O)[C@@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccn2)nn1 InChI=1S/C21H20N6O5S2/c28-16-6-4-14(5-7-16)11-18(21(29)25-30)27-13-15(24-26-27)12-23-34(31,32)20-9-8-19(33-20)17-3-1-2-10-22-17/h1-10,13,18,23,28,30H,11-12H2,(H,25,29)/t18-/m1/s1 QHHWCHMBFWYFFS-GOSISDBHSA-N 661073 (R)-N-hydroxy-3-(4-hydroxyphenyl)-2-(4-((5-(pyridin-2-yl)thiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 20 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661073&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391979 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccc3)nn2)cc1OC InChI=1S/C24H25N5O6S2/c1-34-20-9-8-16(13-21(20)35-2)12-19(24(30)27-31)29-15-18(26-28-29)14-25-37(32,33)23-11-10-22(36-23)17-6-4-3-5-7-17/h3-11,13,15,19,25,31H,12,14H2,1-2H3,(H,27,30)/t19-/m0/s1 YOUGGCOPBSDXKA-IBGZPJMESA-N 661096 (2S)-3-(3,4-dimethoxyphenyl)-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 42 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <500 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661096&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391980 CN(Cc1cn(nn1)[C@@H](Cc1c[nH]c2ccccc12)C(=O)NO)S(=O)(=O)c1ccc(s1)-c1ccccc1 661056 (S)-N-hydroxy-3-(1H-indol-3-yl)-2-(4-((N-methyl-5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 3 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661056&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391981 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccc3)nn2)cc1 InChI=1S/C23H23N5O5S2/c1-33-19-9-7-16(8-10-19)13-20(23(29)26-30)28-15-18(25-27-28)14-24-35(31,32)22-12-11-21(34-22)17-5-3-2-4-6-17/h2-12,15,20,24,30H,13-14H2,1H3,(H,26,29)/t20-/m0/s1 QHHKXYPPDICVAU-FQEVSTJZSA-N 661077 (S)-N-hydroxy-3-(4-methoxyphenyl)-2-(4-((5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 24 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661077&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391982 COc1cccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccn3)nn2)c1 InChI=1S/C22H22N6O5S2/c1-33-17-6-4-5-15(11-17)12-19(22(29)26-30)28-14-16(25-27-28)13-24-35(31,32)21-9-8-20(34-21)18-7-2-3-10-23-18/h2-11,14,19,24,30H,12-13H2,1H3,(H,26,29)/t19-/m0/s1 IIYNHWVYZTWKNO-IBGZPJMESA-N 661103 (2S)-3-(3-methoxyphenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 49 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661103&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391983 ONC(=O)[C@H](Cc1c[nH]c2ccccc12)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 661057 (S)-N-hydroxy-3-(1H-indol-3-yl)-2-(4-((5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 4 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661057&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391984 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccn3)nn2)cc1 InChI=1S/C22H22N6O5S2/c1-33-17-7-5-15(6-8-17)12-19(22(29)26-30)28-14-16(25-27-28)13-24-35(31,32)21-10-9-20(34-21)18-4-2-3-11-23-18/h2-11,14,19,24,30H,12-13H2,1H3,(H,26,29)/t19-/m0/s1 VCCACZUFRCVVFN-IBGZPJMESA-N 661078 (S)-N-hydroxy-3-(4-methoxyphenyl)-2-(4-((5-(pyridin-2-yl)thiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 25 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661078&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 7SH0 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391985 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccn3)nn2)cc1F InChI=1S/C22H21FN6O5S2/c1-34-19-6-5-14(10-16(19)23)11-18(22(30)27-31)29-13-15(26-28-29)12-25-36(32,33)21-8-7-20(35-21)17-4-2-3-9-24-17/h2-10,13,18,25,31H,11-12H2,1H3,(H,27,30)/t18-/m0/s1 ASAWCOCZVNCSLB-SFHVURJKSA-N 661106 (2S)-3-(3-fluoro-4-methoxy-phenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 52 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661106&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391986 ONC(=O)[C@H](Cc1c[nH]c2ccccc12)n1cc(CNS(=O)(=O)c2ccc(Br)s2)nn1 661058 (S)-2-(4-((5-bromothiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)-N-hydroxy-3-(1H-indol-3-yl)propanamide::US20240101542, Compound 5 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661058&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391987 ONC(=O)C[C@H](Cc1ccc(O)cc1)n1nncc1CNS(=O)(=O)c1ccc(s1)-c1ccccn1 InChI=1S/C22H22N6O5S2/c29-18-6-4-15(5-7-18)11-16(12-21(30)26-31)28-17(13-24-27-28)14-25-35(32,33)22-9-8-20(34-22)19-3-1-2-10-23-19/h1-10,13,16,25,29,31H,11-12,14H2,(H,26,30)/t16-/m0/s1 LWNJKRUKVSPFJT-INIZCTEOSA-N 661087 (3S)-4-(4-hydroxyphenyl)-3-[5-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]butanehydroxamic acid::US20240101542, Compound 33 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661087&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391988 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccn3)nn2)cc1Cl InChI=1S/C22H21ClN6O5S2/c1-34-19-6-5-14(10-16(19)23)11-18(22(30)27-31)29-13-15(26-28-29)12-25-36(32,33)21-8-7-20(35-21)17-4-2-3-9-24-17/h2-10,13,18,25,31H,11-12H2,1H3,(H,27,30)/t18-/m0/s1 BSCLLDBQRBYJMT-SFHVURJKSA-N 661107 (2S)-3-(3-chloro-4-methoxy-phenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 53 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661107&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391989 ONC(=O)C[C@@H](Cc1ccc2ccccc2c1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C27H25N5O4S2/c33-26(30-34)16-24(15-19-10-11-20-6-4-5-9-22(20)14-19)32-18-23(29-31-32)17-28-38(35,36)27-13-12-25(37-27)21-7-2-1-3-8-21/h1-14,18,24,28,34H,15-17H2,(H,30,33)/t24-/m1/s1 DCRMODRXEZHGOZ-XMMPIXPASA-N 661059 (R)-N-hydroxy-4-(naphthalen-2-yl)-3-(4-((5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)butanamide::US20240101542, Compound 6 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661059&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391990 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccncc3)nn2)cc1 InChI=1S/C22H22N6O5S2/c1-33-18-4-2-15(3-5-18)12-19(22(29)26-30)28-14-17(25-27-28)13-24-35(31,32)21-7-6-20(34-21)16-8-10-23-11-9-16/h2-11,14,19,24,30H,12-13H2,1H3,(H,26,29)/t19-/m0/s1 PZORSBNPBXPZJN-IBGZPJMESA-N 661090 (2S)-3-(4-methoxyphenyl)-2-[4-[[[5-(4-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 36 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661090&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391991 ONC(=O)[C@H](Cc1ccc(cc1)C#C)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C24H21N5O4S2/c1-2-17-8-10-18(11-9-17)14-21(24(30)27-31)29-16-20(26-28-29)15-25-35(32,33)23-13-12-22(34-23)19-6-4-3-5-7-19/h1,3-13,16,21,25,31H,14-15H2,(H,27,30)/t21-/m0/s1 GNRYGLXPVKEJQU-NRFANRHFSA-N 661108 (2S)-3-(4-ethynylphenyl)-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 54 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661108&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391992 ONC(=O)[C@@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C22H21N5O5S2/c28-18-8-6-15(7-9-18)12-19(22(29)25-30)27-14-17(24-26-27)13-23-34(31,32)21-11-10-20(33-21)16-4-2-1-3-5-16/h1-11,14,19,23,28,30H,12-13H2,(H,25,29)/t19-/m1/s1 PVCQYLNVJILBDA-LJQANCHMSA-N 661061 (R)-N-hydroxy-3-(4-hydroxyphenyl)-2-(4-((5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 8 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661061&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391993 ONC(=O)[C@H](Cc1ccc2OCOc2c1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccn2)nn1 InChI=1S/C22H20N6O6S2/c29-22(26-30)17(9-14-4-5-18-19(10-14)34-13-33-18)28-12-15(25-27-28)11-24-36(31,32)21-7-6-20(35-21)16-3-1-2-8-23-16/h1-8,10,12,17,24,30H,9,11,13H2,(H,26,29)/t17-/m0/s1 YRNZRANQKNATJL-KRWDZBQOSA-N 661091 (2S)-3-(1,3-benzodioxol-5-yl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 37 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661091&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391994 ONC(=O)[C@H](Cc1ccc(cc1)C(=N)NO)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C23H23N7O5S2/c24-22(27-32)17-8-6-15(7-9-17)12-19(23(31)28-33)30-14-18(26-29-30)13-25-37(34,35)21-11-10-20(36-21)16-4-2-1-3-5-16/h1-11,14,19,25,32-33H,12-13H2,(H2,24,27)(H,28,31)/t19-/m0/s1 SKFNPAAILCLMDT-IBGZPJMESA-N 661109 (2S)-3-[4-(N-hydroxycarbamimidoyl)phenyl]-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 55 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661109&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391995 ONC(=O)[C@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C22H21N5O5S2/c28-18-8-6-15(7-9-18)12-19(22(29)25-30)27-14-17(24-26-27)13-23-34(31,32)21-11-10-20(33-21)16-4-2-1-3-5-16/h1-11,14,19,23,28,30H,12-13H2,(H,25,29)/t19-/m0/s1 PVCQYLNVJILBDA-IBGZPJMESA-N 661063 (S)-N-hydroxy-3-(4-hydroxyphenyl)-2-(4-((5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 10 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661063&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391996 ONC(=O)[C@H](Cc1ccc(O)c(Cl)c1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C22H20ClN5O5S2/c23-17-10-14(6-7-19(17)29)11-18(22(30)26-31)28-13-16(25-27-28)12-24-35(32,33)21-9-8-20(34-21)15-4-2-1-3-5-15/h1-10,13,18,24,29,31H,11-12H2,(H,26,30)/t18-/m0/s1 UMGDCNTUWDESGY-SFHVURJKSA-N 661094 (2S)-3-(3-chloro-4-hydroxy-phenyl)-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 40 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661094&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391997 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3cnc(s3)-c3ccccc3)nn2)cc1 InChI=1S/C22H22N6O5S2/c1-33-18-9-7-15(8-10-18)11-19(21(29)26-30)28-14-17(25-27-28)12-24-35(31,32)20-13-23-22(34-20)16-5-3-2-4-6-16/h2-10,13-14,19,24,30H,11-12H2,1H3,(H,26,29)/t19-/m0/s1 HIUGNDQGPDHAQW-IBGZPJMESA-N 661110 (2)-3-(4-methoxyphenyl)-2-[4-[[(2-phenylthiazol-5-yl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 56 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661110&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391998 NCc1ccc(cc1)-c1ccc(s1)S(=O)(=O)[N-]Cc1cn(nn1)[C@@H](Cc1ccc(O)cc1)C(=O)N[O-] InChI=1S/C23H22N6O5S2/c24-12-16-1-5-17(6-2-16)21-9-10-22(35-21)36(33,34)25-13-18-14-29(28-26-18)20(23(31)27-32)11-15-3-7-19(30)8-4-15/h1-10,14,20H,11-13,24H2,(H2-,26,27,28,30,31,32)/q-2/t20-/m0/s1 QPFXUBHLSTYUAG-FQEVSTJZSA-N 661065 (S)-2-(4-((5-(4-(aminomethyl)phenyl)thiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)-N-hydroxy-3-(4-hydroxyphenyl)propanamide, dipotassium salt::US20240101542, Compound 12 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661065&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 171665286 496709548 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 5K1V,5AB2,5CU5,4JBS,4E36,7PFS,7P7P,7NSK,7NUP,7SH0,5J6S,5AB0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1391999 CNC(=O)c1cccc(c1)-c1ccc(s1)S(=O)(=O)NCc1cn(nn1)[C@@H](Cc1ccc(OC)cc1)C(=O)NO InChI=1S/C25H26N6O6S2/c1-26-24(32)18-5-3-4-17(13-18)22-10-11-23(38-22)39(35,36)27-14-19-15-31(30-28-19)21(25(33)29-34)12-16-6-8-20(37-2)9-7-16/h3-11,13,15,21,27,34H,12,14H2,1-2H3,(H,26,32)(H,29,33)/t21-/m0/s1 DVPJLFBQZHLSAB-NRFANRHFSA-N 661097 3-[5-[[1-[(1S)-2-(hydroxyamino)-1-[(4-methoxyphenyl)methyl]-2-oxo-ethyl]triazol-4-yl]methylsulfamoyl]-2-thienyl]-N-methyl-benzamide::US20240101542, Compound 43 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661097&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392000 COc1ccc(C[C@@H](C(=O)NO)n2cc(CN(C3CC3)S(=O)(=O)c3ccc(s3)-c3ccccc3)nn2)cc1 InChI=1S/C26H27N5O5S2/c1-36-22-11-7-18(8-12-22)15-23(26(32)28-33)30-16-20(27-29-30)17-31(21-9-10-21)38(34,35)25-14-13-24(37-25)19-5-3-2-4-6-19/h2-8,11-14,16,21,23,33H,9-10,15,17H2,1H3,(H,28,32)/t23-/m0/s1 WHSAXVGNFTVXKC-QHCPKHFHSA-N 661111 (2S)-2-[4-[cyclopropyl-[[5-(2-pyridyl)-2-thienyl]sulfonyl]amino]methyl]triazol-1-yl]-3-(4-methoxyphenyl)propanehydroxamic acid::US20240101542, Compound 57 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661111&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392001 CN(Cc1cn(nn1)[C@@H](Cc1ccc(O)cc1)C(=O)NO)S(=O)(=O)c1ccc(s1)-c1ccccc1 InChI=1S/C23H23N5O5S2/c1-27(35(32,33)22-12-11-21(34-22)17-5-3-2-4-6-17)14-18-15-28(26-24-18)20(23(30)25-31)13-16-7-9-19(29)10-8-16/h2-12,15,20,29,31H,13-14H2,1H3,(H,25,30)/t20-/m0/s1 UTKGKEZZOINOTB-FQEVSTJZSA-N 661066 (S)-N-hydroxy-3-(4-hydroxyphenyl)-2-(4-((N-methyl-5-phenylthiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 13 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661066&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392002 ONC(=O)[C@H](Cc1ccc(O)c(F)c1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccn2)nn1 InChI=1S/C21H19FN6O5S2/c22-15-9-13(4-5-18(15)29)10-17(21(30)26-31)28-12-14(25-27-28)11-24-35(32,33)20-7-6-19(34-20)16-3-1-2-8-23-16/h1-9,12,17,24,29,31H,10-11H2,(H,26,30)/t17-/m0/s1 WSBLRUKTTAXWIP-KRWDZBQOSA-N 661098 (2S)-3-(3-fluoro-4-hydroxy-phenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 44 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661098&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392003 COc1ccc(C[C@@H](C(=O)NO)n2cc(nn2)C2CCCCN2S(=O)(=O)c2ccc(s2)-c2ccccc2)cc1 InChI=1S/C27H29N5O5S2/c1-37-21-12-10-19(11-13-21)17-24(27(33)29-34)31-18-22(28-30-31)23-9-5-6-16-32(23)39(35,36)26-15-14-25(38-26)20-7-3-2-4-8-20/h2-4,7-8,10-15,18,23-24,34H,5-6,9,16-17H2,1H3,(H,29,33)/t23?,24-/m0/s1 FHHSUVLDWBQCKX-CGAIIQECSA-N 661112 (2S)-3-(4-methoxyphenyl)-2-[4-[1-[(5-phenyl-2-thienyl)sulfonyl]-2-piperidyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 58 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661112&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392004 ONC(=O)[C@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2ccc(Br)s2)nn1 InChI=1S/C16H16BrN5O5S2/c17-14-5-6-15(28-14)29(26,27)18-8-11-9-22(21-19-11)13(16(24)20-25)7-10-1-3-12(23)4-2-10/h1-6,9,13,18,23,25H,7-8H2,(H,20,24)/t13-/m0/s1 DBLMGAUEGQWJLT-ZDUSSCGKSA-N 661067 (S)-2-(4-((5-bromothiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)-N-hydroxy-3-(4-hydroxyphenyl)propanamide::US20240101542, Compound 14 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661067&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392005 ONC(=O)[C@H](Cc1ccc(O)c(F)c1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C22H20FN5O5S2/c23-17-10-14(6-7-19(17)29)11-18(22(30)26-31)28-13-16(25-27-28)12-24-35(32,33)21-9-8-20(34-21)15-4-2-1-3-5-15/h1-10,13,18,24,29,31H,11-12H2,(H,26,30)/t18-/m0/s1 JIYKCQATWPUTBM-SFHVURJKSA-N 661099 (2S)-3-(3-fluoro-4-hydroxy-phenyl)-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 45 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661099&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392006 COc1ccc(C[C@@H](C(=O)NO)n2cc(nn2)[C@@H]2CCCN2S(=O)(=O)c2ccc(s2)-c2ccccc2)cc1 InChI=1S/C26H27N5O5S2/c1-36-20-11-9-18(10-12-20)16-23(26(32)28-33)30-17-21(27-29-30)22-8-5-15-31(22)38(34,35)25-14-13-24(37-25)19-6-3-2-4-7-19/h2-4,6-7,9-14,17,22-23,33H,5,8,15-16H2,1H3,(H,28,32)/t22-,23-/m0/s1 VLXKCGXLXGRWIP-GOTSBHOMSA-N 661113 (2S)-3-(4-methoxyphenyl)-2-[4-[(2S)-1-[(5-phenyl-2-thienyl)sulfonyl]pyrrolidin-2-yl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 59 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661113&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392007 ONC(=O)[C@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2cccs2)nn1 InChI=1S/C16H17N5O5S2/c22-13-5-3-11(4-6-13)8-14(16(23)19-24)21-10-12(18-20-21)9-17-28(25,26)15-2-1-7-27-15/h1-7,10,14,17,22,24H,8-9H2,(H,19,23)/t14-/m0/s1 CBJZRCCMJULOMA-AWEZNQCLSA-N 661068 (S)-N-hydroxy-3-(4-hydroxyphenyl)-2-(4-((thiophene-2-sulfonamido)methyl)-1H-1,2,3-triazol-1-yl)propanamide::US20240101542, Compound 15 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661068&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392008 CNC(=O)c1ccc(cc1)-c1ccc(s1)S(=O)(=O)NCc1cn(nn1)[C@@H](Cc1ccc(OC)cc1)C(=O)NO InChI=1S/C25H26N6O6S2/c1-26-24(32)18-7-5-17(6-8-18)22-11-12-23(38-22)39(35,36)27-14-19-15-31(30-28-19)21(25(33)29-34)13-16-3-9-20(37-2)10-4-16/h3-12,15,21,27,34H,13-14H2,1-2H3,(H,26,32)(H,29,33)/t21-/m0/s1 PSWHCOXIMQCCPK-NRFANRHFSA-N 661081 (S)-4-(5-(N-((1-(1-(hydroxyamino)-3-(4-methoxyphenyl)-1-oxopropan-2-yl)-1H-1,2,3-triazol-4-yl)methyl)sulfamoyl)thiophen-2-yl)-N-methylbenzamide::US20240101542, Compound 28 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661081&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392009 ONC(=O)[C@H](Cc1ccc(cc1)C#N)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccc2)nn1 InChI=1S/C23H20N6O4S2/c24-13-17-8-6-16(7-9-17)12-20(23(30)27-31)29-15-19(26-28-29)14-25-35(32,33)22-11-10-21(34-22)18-4-2-1-3-5-18/h1-11,15,20,25,31H,12,14H2,(H,27,30)/t20-/m0/s1 RTPPVUCGXDDZSJ-FQEVSTJZSA-N 661114 (2S)-3-(4-cyanophenyl)-2-[4-[[(5-phenyl-2-thienyl)sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 60 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661114&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392010 ONC(=O)[C@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2ccsc2)nn1 InChI=1S/C16H17N5O5S2/c22-13-3-1-11(2-4-13)7-15(16(23)19-24)21-9-12(18-20-21)8-17-28(25,26)14-5-6-27-10-14/h1-6,9-10,15,17,22,24H,7-8H2,(H,19,23)/t15-/m0/s1 XTYGGWIJDSJYDO-HNNXBMFYSA-N 661070 (2S)-3-(4-hydroxyphenyl)-2-[4-[(3-thienylsulfonylamino)methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 17 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661070&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392011 ONC(=O)[C@H](Cc1ccc(O)c(Cl)c1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccn2)nn1 InChI=1S/C21H19ClN6O5S2/c22-15-9-13(4-5-18(15)29)10-17(21(30)26-31)28-12-14(25-27-28)11-24-35(32,33)20-7-6-19(34-20)16-3-1-2-8-23-16/h1-9,12,17,24,29,31H,10-11H2,(H,26,30)/t17-/m0/s1 QUVUJUACRAJBHZ-KRWDZBQOSA-N 661093 (2S)-3-(3-chloro-4-hydroxy-phenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 39 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661093&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392012 ONC(=O)[C@H](Cc1ccc(O)cc1)n1cc(CNS(=O)(=O)c2ccc(s2)-c2ccccn2)nn1 InChI=1S/C21H20N6O5S2/c28-16-6-4-14(5-7-16)11-18(21(29)25-30)27-13-15(24-26-27)12-23-34(31,32)20-9-8-19(33-20)17-3-1-2-10-22-17/h1-10,13,18,23,28,30H,11-12H2,(H,25,29)/t18-/m0/s1 QHHWCHMBFWYFFS-SFHVURJKSA-N 661072 (2S)-3-(4-hydroxyphenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 19 Endoplasmic reticulum aminopeptidase 2 Homo sapiens >5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661072&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 7NSK 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2 1392013 COc1ccc(C[C@@H](C(=O)NO)n2cc(CNS(=O)(=O)c3ccc(s3)-c3ccccn3)nn2)cc1OC InChI=1S/C23H24N6O6S2/c1-34-19-7-6-15(12-20(19)35-2)11-18(23(30)27-31)29-14-16(26-28-29)13-25-37(32,33)22-9-8-21(36-22)17-5-3-4-10-24-17/h3-10,12,14,18,25,31H,11,13H2,1-2H3,(H,27,30)/t18-/m0/s1 IWTATGVHZGOSEK-SFHVURJKSA-N 661095 (2S)-3-(3,4-dimethoxyphenyl)-2-[4-[[[5-(2-pyridyl)-2-thienyl]sulfonylamino]methyl]triazol-1-yl]propanehydroxamic acid::US20240101542, Compound 41 Endoplasmic reticulum aminopeptidase 2 Homo sapiens <5000 US Patent 10.7270/Q2FJ2N2P US20240101542 POULAIN, RD; GEALAGEAS, R; CAMBERLEIN, V; FLEAU, CT; GUILLAUME, V; BOSC, D; DEPREZ, B; SIEROCKI, P Universite De Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=661095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50003784&target=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=661095&enzyme=Endoplasmic+reticulum+aminopeptidase+2&column=ki&startPg=0&Increment=50&submit=Search 1 MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT 4E36,4JBS,5AB0,5AB2,5CU5,5J6S,5K1V,7NSK,7NUP,7P7P,7PFS,7SH0 Endoplasmic reticulum aminopeptidase 2 ERAP2_HUMAN Q6P179 Q7Z5K1 Q8TD32 Q8WVJ4 Q9HBX2