BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 50081469 CC(C)Cc1cc(cc2CCNC(=O)c12)-n1cc(C)c2c1CC(C)(C)CC2=O InChI=1S/C24H30N2O2/c1-14(2)8-17-10-18(9-16-6-7-25-23(28)22(16)17)26-13-15(3)21-19(26)11-24(4,5)12-20(21)27/h9-10,13-14H,6-8,11-12H2,1-5H3,(H,25,28) WLNBQNXELZHTAX-UHFFFAOYSA-N 50003865 CHEMBL3235352 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003865&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2R6 4O09 73437615 242056492 CHEMBL3235352 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081470 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)C1CCCC1 InChI=1S/C25H30N2O2/c1-15-14-27(20-12-25(2,3)13-21(28)22(15)20)18-10-17-8-9-26-24(29)23(17)19(11-18)16-6-4-5-7-16/h10-11,14,16H,4-9,12-13H2,1-3H3,(H,26,29) AMWZXPSBURRZMG-UHFFFAOYSA-N 50003868 CHEMBL3235353 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003868&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2QA 4O0B 73437616 242056493 CHEMBL3235353 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081471 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)C1CCCCC1 InChI=1S/C26H32N2O2/c1-16-15-28(21-13-26(2,3)14-22(29)23(16)21)19-11-18-9-10-27-25(30)24(18)20(12-19)17-7-5-4-6-8-17/h11-12,15,17H,4-10,13-14H2,1-3H3,(H,27,30) MHLWEVMLBXNHQO-UHFFFAOYSA-N 50003869 CHEMBL3235354 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003869&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654630 242056494 CHEMBL3235354 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081472 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)C1CCOCC1 InChI=1S/C25H30N2O3/c1-15-14-27(20-12-25(2,3)13-21(28)22(15)20)18-10-17-4-7-26-24(29)23(17)19(11-18)16-5-8-30-9-6-16/h10-11,14,16H,4-9,12-13H2,1-3H3,(H,26,29) IULUGODLBRFXLM-UHFFFAOYSA-N 50003870 CHEMBL3235355 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003870&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654631 242056495 CHEMBL3235355 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081473 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)C1CCC1 InChI=1S/C24H28N2O2/c1-14-13-26(19-11-24(2,3)12-20(27)21(14)19)17-9-16-7-8-25-23(28)22(16)18(10-17)15-5-4-6-15/h9-10,13,15H,4-8,11-12H2,1-3H3,(H,25,28) AYDNYYSKMLWXOR-UHFFFAOYSA-N 50003871 CHEMBL3235356 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003871&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654632 242056496 CHEMBL3235356 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081474 CCCCc1cc(cc2CCNC(=O)c12)-n1cc(C)c2c1CC(C)(C)CC2=O InChI=1S/C24H30N2O2/c1-5-6-7-16-10-18(11-17-8-9-25-23(28)22(16)17)26-14-15(2)21-19(26)12-24(3,4)13-20(21)27/h10-11,14H,5-9,12-13H2,1-4H3,(H,25,28) MPDUIKXWFJHUBM-UHFFFAOYSA-N 50003872 CHEMBL3235357 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003872&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654633 242056497 CHEMBL3235357 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081475 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)C(C)(C)C InChI=1S/C24H30N2O2/c1-14-13-26(18-11-24(5,6)12-19(27)20(14)18)16-9-15-7-8-25-22(28)21(15)17(10-16)23(2,3)4/h9-10,13H,7-8,11-12H2,1-6H3,(H,25,28) FLANSLWVOMGKFX-UHFFFAOYSA-N 50003873 CHEMBL3235358 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003873&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654634 242056498 CHEMBL3235358 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081476 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc(Cc2ccccc2)c2C(=O)NCCc2c1 InChI=1S/C27H28N2O2/c1-17-16-29(22-14-27(2,3)15-23(30)24(17)22)21-12-19-9-10-28-26(31)25(19)20(13-21)11-18-7-5-4-6-8-18/h4-8,12-13,16H,9-11,14-15H2,1-3H3,(H,28,31) LIRXYOSHRDKVEH-UHFFFAOYSA-N 50003875 CHEMBL3235359 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003875&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654635 242056499 CHEMBL3235359 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081477 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)-c1ccccc1 InChI=1S/C26H26N2O2/c1-16-15-28(21-13-26(2,3)14-22(29)23(16)21)19-11-18-9-10-27-25(30)24(18)20(12-19)17-7-5-4-6-8-17/h4-8,11-12,15H,9-10,13-14H2,1-3H3,(H,27,30) VBVXWYMKVOTMBY-UHFFFAOYSA-N 50003876 CHEMBL3235360 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003876&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654636 242056500 CHEMBL3235360 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081478 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)-c1ccc(F)cc1 InChI=1S/C26H25FN2O2/c1-15-14-29(21-12-26(2,3)13-22(30)23(15)21)19-10-17-8-9-28-25(31)24(17)20(11-19)16-4-6-18(27)7-5-16/h4-7,10-11,14H,8-9,12-13H2,1-3H3,(H,28,31) BASLFXHBMHSLDF-UHFFFAOYSA-N 50003877 CHEMBL3235361 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003877&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654637 242056501 CHEMBL3235361 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081479 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)-c1cccc(F)c1 InChI=1S/C26H25FN2O2/c1-15-14-29(21-12-26(2,3)13-22(30)23(15)21)19-10-17-7-8-28-25(31)24(17)20(11-19)16-5-4-6-18(27)9-16/h4-6,9-11,14H,7-8,12-13H2,1-3H3,(H,28,31) OUIASJZGMFCFQE-UHFFFAOYSA-N 50003878 CHEMBL3235362 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003878&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654638 242056502 CHEMBL3235362 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081480 COc1ccc(cc1)-c1cc(cc2CCNC(=O)c12)-n1cc(C)c2c1CC(C)(C)CC2=O InChI=1S/C27H28N2O3/c1-16-15-29(22-13-27(2,3)14-23(30)24(16)22)19-11-18-9-10-28-26(31)25(18)21(12-19)17-5-7-20(32-4)8-6-17/h5-8,11-12,15H,9-10,13-14H2,1-4H3,(H,28,31) MNPDTLDITGFXDG-UHFFFAOYSA-N 50003880 CHEMBL3235363 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003880&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654639 242056504 CHEMBL3235363 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081605 CC1(C)Cc2c(C(=O)C1)c1ncccc1n2-c1ccc(cc1)C(N)=O InChI=1S/C20H19N3O2/c1-20(2)10-15-17(16(24)11-20)18-14(4-3-9-22-18)23(15)13-7-5-12(6-8-13)19(21)25/h3-9H,10-11H2,1-2H3,(H2,21,25) UFMAOJSGSUPWKJ-UHFFFAOYSA-N 50003904 CHEMBL3235326 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003904&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654661 242056523 CHEMBL3235326 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081606 CC1(C)Cc2c(C(=O)C1)c1ccncc1n2-c1ccc(cc1)C(N)=O InChI=1S/C20H19N3O2/c1-20(2)9-15-18(17(24)10-20)14-7-8-22-11-16(14)23(15)13-5-3-12(4-6-13)19(21)25/h3-8,11H,9-10H2,1-2H3,(H2,21,25) AUSDCBVXEDICDC-UHFFFAOYSA-N 50003905 CHEMBL3235327 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003905&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654662 242056524 CHEMBL3235327 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081607 CC1(C)Cc2c(C(=O)C1)c1cccnc1n2-c1ccc(cc1)C(N)=O InChI=1S/C20H19N3O2/c1-20(2)10-15-17(16(24)11-20)14-4-3-9-22-19(14)23(15)13-7-5-12(6-8-13)18(21)25/h3-9H,10-11H2,1-2H3,(H2,21,25) HRAHZTQZEHLPAG-UHFFFAOYSA-N 50003906 CHEMBL3235328 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003906&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654663 242056525 CHEMBL3235328 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081608 CC1(C)Cc2c(c3CCCCc3n2-c2ccc(cc2)C(N)=O)C(=O)C1 InChI=1S/C21H24N2O2/c1-21(2)11-17-19(18(24)12-21)15-5-3-4-6-16(15)23(17)14-9-7-13(8-10-14)20(22)25/h7-10H,3-6,11-12H2,1-2H3,(H2,22,25) DDLFNBQRUWNLSN-UHFFFAOYSA-N 50003907 CHEMBL3235329 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003907&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654664 242056526 CHEMBL3235329 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081609 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(cc1)C(N)=O InChI=1S/C21H25N3O2/c1-21(2)10-16-19(18(25)11-21)15-8-9-23(3)12-17(15)24(16)14-6-4-13(5-7-14)20(22)26/h4-7H,8-12H2,1-3H3,(H2,22,26) SMJJAAHWGIEVIU-UHFFFAOYSA-N 50003908 CHEMBL3235330 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003908&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2Q8 4O04 90654665 242056527 CHEMBL3235330 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081610 CN1CCCC2C(C1)N(C1=C2C(=O)CC(C)(C)C1)c1ccc(cc1)C(N)=O InChI=1S/C22H29N3O2/c1-22(2)11-17-20(19(26)12-22)16-5-4-10-24(3)13-18(16)25(17)15-8-6-14(7-9-15)21(23)27/h6-9,16,18H,4-5,10-13H2,1-3H3,(H2,23,27) DYLPCDNAHCLYIV-UHFFFAOYSA-N 50003902 CHEMBL3235331 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003902&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654659 242056521 CHEMBL3235331 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081611 CC1(C)Cc2c(c3CCNCc3n2-c2ccc(cc2)C(N)=O)C(=O)C1 InChI=1S/C20H23N3O2/c1-20(2)9-15-18(17(24)10-20)14-7-8-22-11-16(14)23(15)13-5-3-12(4-6-13)19(21)25/h3-6,22H,7-11H2,1-2H3,(H2,21,25) QEIFWHGXYQFXRO-UHFFFAOYSA-N 50003903 CHEMBL3235332 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003903&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654660 242056522 CHEMBL3235332 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081612 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1cc(F)c(C(N)=O)c(N[C@H]2CCOC2)c1 InChI=1S/C25H31FN4O3/c1-25(2)10-19-22(21(31)11-25)16-4-6-29(3)12-20(16)30(19)15-8-17(26)23(24(27)32)18(9-15)28-14-5-7-33-13-14/h8-9,14,28H,4-7,10-13H2,1-3H3,(H2,27,32)/t14-/m0/s1 TYKPZVLPLZTMTM-AWEZNQCLSA-N 50003881 CHEMBL3235333 Heat shock protein 75 kDa, mitochondrial Homo sapiens 8500 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003881&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654640 242056505 CHEMBL3235333 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081613 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(N[C@H]2CCOC2)c1 InChI=1S/C25H32N4O3/c1-25(2)11-20-23(22(30)12-25)18-6-8-28(3)13-21(18)29(20)16-4-5-17(24(26)31)19(10-16)27-15-7-9-32-14-15/h4-5,10,15,27H,6-9,11-14H2,1-3H3,(H2,26,31)/t15-/m0/s1 OHEUYKZRNQMPTL-HNNXBMFYSA-N 50003883 CHEMBL3235334 Heat shock protein 75 kDa, mitochondrial Homo sapiens 5000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003883&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654641 242056506 CHEMBL3235334 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081614 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NC2CCCC2)c1 InChI=1S/C26H34N4O2/c1-26(2)13-21-24(23(31)14-26)19-10-11-29(3)15-22(19)30(21)17-8-9-18(25(27)32)20(12-17)28-16-6-4-5-7-16/h8-9,12,16,28H,4-7,10-11,13-15H2,1-3H3,(H2,27,32) FRDWFVYYRVMIEO-UHFFFAOYSA-N 50003884 CHEMBL3235335 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1700 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003884&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654642 242056507 CHEMBL3235335 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081615 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NCC2CC2)c1 InChI=1S/C25H32N4O2/c1-25(2)11-20-23(22(30)12-25)18-8-9-28(3)14-21(18)29(20)16-6-7-17(24(26)31)19(10-16)27-13-15-4-5-15/h6-7,10,15,27H,4-5,8-9,11-14H2,1-3H3,(H2,26,31) XGHMJWBQMCKFLJ-UHFFFAOYSA-N 50003885 CHEMBL3235336 Heat shock protein 75 kDa, mitochondrial Homo sapiens 4500 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003885&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654643 242056508 CHEMBL3235336 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081616 COCCNc1cc(ccc1C(N)=O)-n1c2CN(C)CCc2c2c1CC(C)(C)CC2=O InChI=1S/C24H32N4O3/c1-24(2)12-19-22(21(29)13-24)17-7-9-27(3)14-20(17)28(19)15-5-6-16(23(25)30)18(11-15)26-8-10-31-4/h5-6,11,26H,7-10,12-14H2,1-4H3,(H2,25,30) JSZMVEDRZLWINJ-UHFFFAOYSA-N 50003886 CHEMBL3235337 Heat shock protein 75 kDa, mitochondrial Homo sapiens 8800 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003886&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654644 242056509 CHEMBL3235337 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081617 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NC2CCSCC2)c1 InChI=1S/C26H34N4O2S/c1-26(2)13-21-24(23(31)14-26)19-6-9-29(3)15-22(19)30(21)17-4-5-18(25(27)32)20(12-17)28-16-7-10-33-11-8-16/h4-5,12,16,28H,6-11,13-15H2,1-3H3,(H2,27,32) FFBBPPCCNBFJPR-UHFFFAOYSA-N 50003887 CHEMBL3235338 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1200 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003887&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654645 103917778 CHEMBL3235338 ZINC22934059 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081618 CCCNc1cc(ccc1C(N)=O)-n1c2CN(C)CCc2c2c1CC(C)(C)CC2=O InChI=1S/C24H32N4O2/c1-5-9-26-18-11-15(6-7-16(18)23(25)30)28-19-12-24(2,3)13-21(29)22(19)17-8-10-27(4)14-20(17)28/h6-7,11,26H,5,8-10,12-14H2,1-4H3,(H2,25,30) XEADAWRYEKBMAU-UHFFFAOYSA-N 50003888 CHEMBL3235339 Heat shock protein 75 kDa, mitochondrial Homo sapiens 5800 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003888&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654646 242056510 CHEMBL3235339 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081619 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NC2CC2)c1 InChI=1S/C24H30N4O2/c1-24(2)11-19-22(21(29)12-24)17-8-9-27(3)13-20(17)28(19)15-6-7-16(23(25)30)18(10-15)26-14-4-5-14/h6-7,10,14,26H,4-5,8-9,11-13H2,1-3H3,(H2,25,30) BGFYCZKQHDTLHW-UHFFFAOYSA-N 50003889 CHEMBL3235340 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003889&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654647 242056511 CHEMBL3235340 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081620 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NCC(F)F)c1 InChI=1S/C23H28F2N4O2/c1-23(2)9-17-21(19(30)10-23)15-6-7-28(3)12-18(15)29(17)13-4-5-14(22(26)31)16(8-13)27-11-20(24)25/h4-5,8,20,27H,6-7,9-12H2,1-3H3,(H2,26,31) HEUKUPZJWOFYNZ-UHFFFAOYSA-N 50003890 CHEMBL3235341 Heat shock protein 75 kDa, mitochondrial Homo sapiens 7400 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003890&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654648 242056512 CHEMBL3235341 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081621 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NCC2(C)COC2)c1 InChI=1S/C26H34N4O3/c1-25(2)10-20-23(22(31)11-25)18-7-8-29(4)12-21(18)30(20)16-5-6-17(24(27)32)19(9-16)28-13-26(3)14-33-15-26/h5-6,9,28H,7-8,10-15H2,1-4H3,(H2,27,32) BBERRDWXGILBQQ-UHFFFAOYSA-N 50003891 CHEMBL3235342 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1200 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003891&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654649 242056513 CHEMBL3235342 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081622 CC(C)Nc1cc(ccc1C(N)=O)-n1c2CN(C)CCc2c2c1CC(C)(C)CC2=O InChI=1S/C24H32N4O2/c1-14(2)26-18-10-15(6-7-16(18)23(25)30)28-19-11-24(3,4)12-21(29)22(19)17-8-9-27(5)13-20(17)28/h6-7,10,14,26H,8-9,11-13H2,1-5H3,(H2,25,30) GQTAYJHCNIDUJF-UHFFFAOYSA-N 50003892 CHEMBL3235343 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003892&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654650 103917779 CHEMBL3235343 ZINC22934132 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081623 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(NCC(C)(C)C)c1 InChI=1S/C26H36N4O2/c1-25(2,3)15-28-19-11-16(7-8-17(19)24(27)32)30-20-12-26(4,5)13-22(31)23(20)18-9-10-29(6)14-21(18)30/h7-8,11,28H,9-10,12-15H2,1-6H3,(H2,27,32) CMUOQACBLLCUQL-UHFFFAOYSA-N 50003893 CHEMBL3235344 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1400 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003893&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654651 242056514 CHEMBL3235344 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081624 CC(C)Nc1cc(cc2CCNC(=O)c12)-n1c2CN(C)CCc2c2c1CC(C)(C)CC2=O InChI=1S/C26H34N4O2/c1-15(2)28-19-11-17(10-16-6-8-27-25(32)23(16)19)30-20-12-26(3,4)13-22(31)24(20)18-7-9-29(5)14-21(18)30/h10-11,15,28H,6-9,12-14H2,1-5H3,(H,27,32) SAYWXJCRCITRBW-UHFFFAOYSA-N 50003894 CHEMBL3235345 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003894&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2Q9 4O05 90654652 242056515 CHEMBL3235345 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081625 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc2C(=O)NCc2c1 InChI=1S/C22H25N3O2/c1-22(2)9-17-20(19(26)10-22)16-6-7-24(3)12-18(16)25(17)14-4-5-15-13(8-14)11-23-21(15)27/h4-5,8H,6-7,9-12H2,1-3H3,(H,23,27) IWANPRJGCILZPU-UHFFFAOYSA-N 50003895 CHEMBL3235346 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003895&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654653 103917780 CHEMBL3235346 ZINC01851132 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081626 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc2C(=O)NCCc2c1 InChI=1S/C23H27N3O2/c1-23(2)11-18-21(20(27)12-23)17-7-9-25(3)13-19(17)26(18)15-4-5-16-14(10-15)6-8-24-22(16)28/h4-5,10H,6-9,11-13H2,1-3H3,(H,24,28) AVFBSMWWJOVYGJ-UHFFFAOYSA-N 50003897 CHEMBL3235347 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003897&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654654 242056516 CHEMBL3235347 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081627 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc2c(CCCNC2=O)c1 InChI=1S/C24H29N3O2/c1-24(2)12-19-22(21(28)13-24)18-8-10-26(3)14-20(18)27(19)16-6-7-17-15(11-16)5-4-9-25-23(17)29/h6-7,11H,4-5,8-10,12-14H2,1-3H3,(H,25,29) RAINWXVSHGFULP-UHFFFAOYSA-N 50003898 CHEMBL3235348 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003898&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654655 242056517 CHEMBL3235348 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081628 CN1CCc2c(C1)n(c1CC(C)(C)CC(=O)c21)-c1ccc(C(N)=O)c(CCC2CC2)c1 InChI=1S/C26H33N3O2/c1-26(2)13-21-24(23(30)14-26)20-10-11-28(3)15-22(20)29(21)18-8-9-19(25(27)31)17(12-18)7-6-16-4-5-16/h8-9,12,16H,4-7,10-11,13-15H2,1-3H3,(H2,27,31) FACPCCFMMPETLR-UHFFFAOYSA-N 50003899 CHEMBL3235349 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003899&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 90654656 242056518 CHEMBL3235349 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50081629 CC(C)Cc1cc(cc2CCNC(=O)c12)-n1c2CN(C)CCc2c2c1CC(C)(C)CC2=O InChI=1S/C27H35N3O2/c1-16(2)10-18-12-19(11-17-6-8-28-26(32)24(17)18)30-21-13-27(3,4)14-23(31)25(21)20-7-9-29(5)15-22(20)30/h11-12,16H,6-10,13-15H2,1-5H3,(H,28,32) JEHITPSPEWPKHP-UHFFFAOYSA-N 50003900 CHEMBL3235350 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/jm500042s 10.7270/Q2057HGG 24673104 Ernst, JT; Neubert, T; Liu, M; Sperry, S; Zuccola, H; Turnbull, A; Fleck, B; Kargo, W; Woody, L; Chiang, P; Tran, D; Chen, W; Snyder, P; Alcacio, T; Nezami, A; Reynolds, J; Alvi, K; Goulet, L; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003900&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search FGH 4O07 90654657 242056519 CHEMBL3235350 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338111 Nc1ncnc2n(CCCC#C)c(Sc3ccc(Cl)cc3Cl)nc12 InChI=1S/C16H13Cl2N5S/c1-2-3-4-7-23-15-13(14(19)20-9-21-15)22-16(23)24-12-6-5-10(17)8-11(12)18/h1,5-6,8-9H,3-4,7H2,(H2,19,20,21) KNFKPQJGTFXNMB-UHFFFAOYSA-N 50165316 8-(2,4-Dichloro-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL365118 Heat shock protein 75 kDa, mitochondrial Homo sapiens 145400 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165316&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11349446 104050877 CHEMBL365118 ZINC13642755 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338112 Cc1ccc(Sc2nc3c(N)ncnc3n2CCCC#C)c(C)c1 InChI=1S/C18H19N5S/c1-4-5-6-9-23-17-15(16(19)20-11-21-17)22-18(23)24-14-8-7-12(2)10-13(14)3/h1,7-8,10-11H,5-6,9H2,2-3H3,(H2,19,20,21) WLYXAWLTUOYKMO-UHFFFAOYSA-N 50165286 8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL424824 Heat shock protein 75 kDa, mitochondrial Homo sapiens 13800 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165286&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11302159 104050847 CHEMBL424824 ZINC13642753 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338113 Nc1ncnc2n(CCCC#C)c(Sc3cc(Cl)ccc3Cl)nc12 InChI=1S/C16H13Cl2N5S/c1-2-3-4-7-23-15-13(14(19)20-9-21-15)22-16(23)24-12-8-10(17)5-6-11(12)18/h1,5-6,8-9H,3-4,7H2,(H2,19,20,21) QGGASVLFFHJUTI-UHFFFAOYSA-N 50165282 8-(2,5-Dichloro-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL364450 Heat shock protein 75 kDa, mitochondrial Homo sapiens 5100 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165282&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11326407 104050843 CHEMBL364450 ZINC13642759 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338114 Cc1ccc(C)c(Sc2nc3c(N)ncnc3n2CCCC#C)c1 InChI=1S/C18H19N5S/c1-4-5-6-9-23-17-15(16(19)20-11-21-17)22-18(23)24-14-10-12(2)7-8-13(14)3/h1,7-8,10-11H,5-6,9H2,2-3H3,(H2,19,20,21) CJKAUGQAYSVFNU-UHFFFAOYSA-N 50165300 8-(2,5-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL364239 Heat shock protein 75 kDa, mitochondrial Homo sapiens 203700 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165300&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11450570 104050861 CHEMBL364239 ZINC13642757 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338126 Nc1ncnc2n(CCCC#C)c(Sc3cc(Cl)cc(Cl)c3)nc12 InChI=1S/C16H13Cl2N5S/c1-2-3-4-5-23-15-13(14(19)20-9-21-15)22-16(23)24-12-7-10(17)6-11(18)8-12/h1,6-9H,3-5H2,(H2,19,20,21) CTWGQTGRSYPVSO-UHFFFAOYSA-N 50165268 8-(3,5-Dichloro-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL192013 Heat shock protein 75 kDa, mitochondrial Homo sapiens 83600 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165268&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11406285 104050829 CHEMBL192013 ZINC13642771 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338127 Cc1cc(C)cc(Sc2nc3c(N)ncnc3n2CCCC#C)c1 InChI=1S/C18H19N5S/c1-4-5-6-7-23-17-15(16(19)20-11-21-17)22-18(23)24-14-9-12(2)8-13(3)10-14/h1,8-11H,5-7H2,2-3H3,(H2,19,20,21) LTBCYYNIVCRAOE-UHFFFAOYSA-N 50165319 8-(3,5-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL195096 Heat shock protein 75 kDa, mitochondrial Homo sapiens 157900 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165319&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11336657 104050880 CHEMBL195096 ZINC13642773 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338128 Nc1ncnc2n(CCCC#C)c(Sc3cc(Cl)nc(Cl)c3)nc12 InChI=1S/C15H12Cl2N6S/c1-2-3-4-5-23-14-12(13(18)19-8-20-14)22-15(23)24-9-6-10(16)21-11(17)7-9/h1,6-8H,3-5H2,(H2,18,19,20) UFFUNOBLCJEJDR-UHFFFAOYSA-N 50087449 CHEMBL3426736 Heat shock protein 75 kDa, mitochondrial Homo sapiens 9600 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087449&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890187 313083614 CHEMBL3426736 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338129 Nc1ncnc2n(CCCC#C)c(Sc3ccc(Cl)c(Cl)c3Cl)nc12 InChI=1S/C16H12Cl3N5S/c1-2-3-4-7-24-15-13(14(20)21-8-22-15)23-16(24)25-10-6-5-9(17)11(18)12(10)19/h1,5-6,8H,3-4,7H2,(H2,20,21,22) SJJMVWOPNWUEOV-UHFFFAOYSA-N 50087452 CHEMBL3426739 Heat shock protein 75 kDa, mitochondrial Homo sapiens 3600 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087452&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890111 313083617 CHEMBL3426739 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338130 Nc1ncnc2n(CCCC#C)c(Sc3cc(Cl)c(Cl)cc3Cl)nc12 InChI=1S/C16H12Cl3N5S/c1-2-3-4-5-24-15-13(14(20)21-8-22-15)23-16(24)25-12-7-10(18)9(17)6-11(12)19/h1,6-8H,3-5H2,(H2,20,21,22) HKCGVSYYAMBCJV-UHFFFAOYSA-N 50165315 9-Pent-4-ynyl-8-(2,4,5-trichloro-phenylsulfanyl)-9H-purin-6-ylamine::CHEMBL192480::US10676476, Example 2 Heat shock protein 75 kDa, mitochondrial Homo sapiens 78400 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165315&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11223683 104050876 CHEMBL192480 ZINC13642775 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338131 Cc1cc(C)c(Sc2nc3c(N)ncnc3n2CCCC#C)c(C)c1 InChI=1S/C19H21N5S/c1-5-6-7-8-24-18-15(17(20)21-11-22-18)23-19(24)25-16-13(3)9-12(2)10-14(16)4/h1,9-11H,6-8H2,2-4H3,(H2,20,21,22) FFJTXDGAXOSYBK-UHFFFAOYSA-N 50087453 CHEMBL3426740 Heat shock protein 75 kDa, mitochondrial Homo sapiens 65500 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087453&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 71660550 313083618 CHEMBL3426740 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338132 CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) SUPVGFZUWFMATN-UHFFFAOYSA-N 50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9 Heat shock protein 75 kDa, mitochondrial Homo sapiens 205 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180302&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search H71 2FWZ,4Z1F 9549213 104065404 CHEMBL200102 ZINC13679213 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338133 Nc1ncnc2n(CCCC#N)c(Sc3cc(Cl)cc(Cl)c3)nc12 InChI=1S/C15H12Cl2N6S/c16-9-5-10(17)7-11(6-9)24-15-22-12-13(19)20-8-21-14(12)23(15)4-2-1-3-18/h5-8H,1-2,4H2,(H2,19,20,21) MWRFBRVQFKNMML-UHFFFAOYSA-N 50087507 CHEMBL3426748 Heat shock protein 75 kDa, mitochondrial Homo sapiens 4580 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087507&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890354 313083625 CHEMBL3426748 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338134 Nc1ncnc2n(CCc3ccccc3)c(Sc3cc(Cl)cc(Cl)c3)nc12 InChI=1S/C19H15Cl2N5S/c20-13-8-14(21)10-15(9-13)27-19-25-16-17(22)23-11-24-18(16)26(19)7-6-12-4-2-1-3-5-12/h1-5,8-11H,6-7H2,(H2,22,23,24) CVPIOYVUNCZFCF-UHFFFAOYSA-N 50087509 CHEMBL3426750 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087509&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890133 313083627 CHEMBL3426750 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338135 CCCC(C)n1c(Sc2ccc(Cl)cc2Cl)nc2c(N)ncnc12 InChI=1S/C16H17Cl2N5S/c1-3-4-9(2)23-15-13(14(19)20-8-21-15)22-16(23)24-12-6-5-10(17)7-11(12)18/h5-9H,3-4H2,1-2H3,(H2,19,20,21) WBRCSQKAHZWSMP-UHFFFAOYSA-N 50087523 CHEMBL3426755 Heat shock protein 75 kDa, mitochondrial Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087523&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117889863 313083630 CHEMBL3426755 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338136 Nc1ncnc2n(CCC#C)c(Sc3ccc(Cl)cc3Cl)nc12 InChI=1S/C15H11Cl2N5S/c1-2-3-6-22-14-12(13(18)19-8-20-14)21-15(22)23-11-5-4-9(16)7-10(11)17/h1,4-5,7-8H,3,6H2,(H2,18,19,20) VBRMJZNSXXIWMQ-UHFFFAOYSA-N 50087524 CHEMBL3426756 Heat shock protein 75 kDa, mitochondrial Homo sapiens 7230 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087524&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 118737377 313083631 CHEMBL3426756 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338137 CCC(CC#C)n1c(Sc2ccc(Cl)cc2Cl)nc2c(N)ncnc12 InChI=1S/C17H15Cl2N5S/c1-3-5-11(4-2)24-16-14(15(20)21-9-22-16)23-17(24)25-13-7-6-10(18)8-12(13)19/h1,6-9,11H,4-5H2,2H3,(H2,20,21,22) YGUTYYUOAZFJHD-UHFFFAOYSA-N 50087526 CHEMBL3426758 Heat shock protein 75 kDa, mitochondrial Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087526&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890387 313083633 CHEMBL3426758 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338138 Nc1ncnc2n(CCCC#C)c(nc12)C(=O)c1ccc(Cl)cc1Cl InChI=1S/C17H13Cl2N5O/c1-2-3-4-7-24-16-13(15(20)21-9-22-16)23-17(24)14(25)11-6-5-10(18)8-12(11)19/h1,5-6,8-9H,3-4,7H2,(H2,20,21,22) FKXRNDGSXRXKNT-UHFFFAOYSA-N 50087575 CHEMBL3426763 Heat shock protein 75 kDa, mitochondrial Homo sapiens 4980 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087575&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890250 313083637 CHEMBL3426763 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338139 Nc1ncn(CCCC#N)c2nc(Sc3ccc(Cl)cc3Cl)nc12 InChI=1S/C15H12Cl2N6S/c16-9-3-4-11(10(17)7-9)24-15-21-12-13(19)20-8-23(14(12)22-15)6-2-1-5-18/h3-4,7-8H,1-2,6,19H2 HGYDERWAOZJDHO-UHFFFAOYSA-N 50087649 CHEMBL3426768 Heat shock protein 75 kDa, mitochondrial Homo sapiens 9600 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087649&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 118737383 313083642 CHEMBL3426768 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338140 Cc1ccc(Sc2nc3c(N)ncn(CCCC#N)c3n2)c(C)c1 InChI=1S/C17H18N6S/c1-11-5-6-13(12(2)9-11)24-17-21-14-15(19)20-10-23(16(14)22-17)8-4-3-7-18/h5-6,9-10H,3-4,8,19H2,1-2H3 PGSVTCXIHDBDIQ-UHFFFAOYSA-N 50087650 CHEMBL3426769 Heat shock protein 75 kDa, mitochondrial Homo sapiens 54100 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087650&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 118737384 313083643 CHEMBL3426769 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338141 Nc1ncn(CCCC#N)c2nc(Sc3cc(Cl)c(Cl)cc3Cl)nc12 InChI=1S/C15H11Cl3N6S/c16-8-5-10(18)11(6-9(8)17)25-15-22-12-13(20)21-7-24(14(12)23-15)4-2-1-3-19/h5-7H,1-2,4,20H2 BPSOXFKTEGXGJF-UHFFFAOYSA-N 50087715 CHEMBL3426776 Heat shock protein 75 kDa, mitochondrial Homo sapiens 19500 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087715&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 118737390 103986743 CHEMBL3426776 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338142 CC(C)NCCCn1cnc(N)c2nc(Sc3cc(Cl)cc(Cl)c3)nc12 InChI=1S/C17H20Cl2N6S/c1-10(2)21-4-3-5-25-9-22-15(20)14-16(25)24-17(23-14)26-13-7-11(18)6-12(19)8-13/h6-10,21H,3-5,20H2,1-2H3 JXZICEAMGFPHHC-UHFFFAOYSA-N 50087718 CHEMBL3426779 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087718&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117889958 103986746 CHEMBL3426779 ZINC29404186 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338143 CC(C)NCCCn1c(Sc2cc(Cl)cc(Cl)c2)nc2c(N)ncnc12 InChI=1S/C17H20Cl2N6S/c1-10(2)21-4-3-5-25-16-14(15(20)22-9-23-16)24-17(25)26-13-7-11(18)6-12(19)8-13/h6-10,21H,3-5H2,1-2H3,(H2,20,22,23) JYSLFQTWNRYWJT-UHFFFAOYSA-N 50087721 CHEMBL3426781 Heat shock protein 75 kDa, mitochondrial Homo sapiens 7300 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087721&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 71660551 103986749 CHEMBL3426781 ZINC02003131 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338144 CC(C)NCCCn1c(Sc2ccc(Cl)cc2Cl)nc2c(N)nccc12 InChI=1S/C18H21Cl2N5S/c1-11(2)22-7-3-9-25-14-6-8-23-17(21)16(14)24-18(25)26-15-5-4-12(19)10-13(15)20/h4-6,8,10-11,22H,3,7,9H2,1-2H3,(H2,21,23) GIPFWVJXTQVDMH-UHFFFAOYSA-N 50087723 CHEMBL3426782 Heat shock protein 75 kDa, mitochondrial Homo sapiens 14100 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087723&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890473 103986751 CHEMBL3426782 ZINC29400728 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50338145 CC(C)NCCCn1c(Sc2cc(Cl)cc(Cl)c2)nc2c(N)nccc12 InChI=1S/C18H21Cl2N5S/c1-11(2)22-5-3-7-25-15-4-6-23-17(21)16(15)24-18(25)26-14-9-12(19)8-13(20)10-14/h4,6,8-11,22H,3,5,7H2,1-2H3,(H2,21,23) FRGACHKMANBBJE-UHFFFAOYSA-N 50087724 CHEMBL3426783 Heat shock protein 75 kDa, mitochondrial Homo sapiens 7200 ChEMBL 10.1021/acs.jmedchem.5b00197 10.7270/Q2CC12DD 25901531 Patel, HJ; Patel, PD; Ochiana, SO; Yan, P; Sun, W; Patel, MR; Shah, SK; Tramentozzi, E; Brooks, J; Bolaender, A; Shrestha, L; Stephani, R; Finotti, P; Leifer, C; Li, Z; Gewirth, DT; Taldone, T; Chiosis, G Sloan-Kettering Institute for Cancer Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087724&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 117890515 103986752 CHEMBL3426783 ZINC29404180 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50909975 CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32) NDAZATDQFDPQBD-UHFFFAOYSA-N 20926 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide::Isoxazole, 40f::VER-52296/NVP-AUY922 Heat shock protein 75 kDa, mitochondrial Homo sapiens 535 ChEMBL 10.1021/jm9004708 10.7270/Q2GM889J 20055425 Biamonte, MA; Van de Water, R; Arndt, JW; Scannevin, RH; Perret, D; Lee, WC Biogen Idec Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20926&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2GJ 6LTI,2VCI,6CJS,7K9S 10096043 49689000 ZINC14974931 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51088200 COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc23)c1C InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20) QULDDKSCVCJTPV-UHFFFAOYSA-N 20800 2-amino-6-halopurine analogue, 20::6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine::CHEMBL467399::hsp90_107 Heat shock protein 75 kDa, mitochondrial Homo sapiens 62 ChEMBL 10.1016/j.bmcl.2013.11.036 10.7270/Q2NP25WW 24332488 Ernst, JT; Liu, M; Zuccola, H; Neubert, T; Beaumont, K; Turnbull, A; Kallel, A; Vought, B; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20800&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 94M 7S9G,7S9F,3QDD,4Z1G,3O6O 16736529 49688874 CHEMBL467399 ZINC14974583 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51088201 CC1(C)Cc2c(c(nn2-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)C(F)(F)F)C(=O)C1 InChI=1S/C23H27F3N4O3/c1-22(2)10-17-19(18(32)11-22)20(23(24,25)26)29-30(17)13-5-8-15(21(27)33)16(9-13)28-12-3-6-14(31)7-4-12/h5,8-9,12,14,28,31H,3-4,6-7,10-11H2,1-2H3,(H2,27,33)/t12-,14- ZFVRYNYOPQZKDG-MQMHXKEQSA-N 50378702 CHEMBL560895::SNX-2112 Heat shock protein 75 kDa, mitochondrial Homo sapiens 791 ChEMBL 10.1016/j.bmcl.2013.11.036 10.7270/Q2NP25WW 24332488 Ernst, JT; Liu, M; Zuccola, H; Neubert, T; Beaumont, K; Turnbull, A; Kallel, A; Vought, B; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378702&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 24772860 160857785 CHEMBL560895 ZINC36741071 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51088202 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc(F)c(C(N)=O)c(N[C@H]2CCOC2)c1 InChI=1S/C22H26FN3O3/c1-12-10-26(17-8-22(2,3)9-18(27)19(12)17)14-6-15(23)20(21(24)28)16(7-14)25-13-4-5-29-11-13/h6-7,10,13,25H,4-5,8-9,11H2,1-3H3,(H2,24,28)/t13-/m0/s1 GAGDTKJJVCLACJ-ZDUSSCGKSA-N 50445478 CHEMBL3104858 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1195 ChEMBL 10.1016/j.bmcl.2013.11.036 10.7270/Q2NP25WW 24332488 Ernst, JT; Liu, M; Zuccola, H; Neubert, T; Beaumont, K; Turnbull, A; Kallel, A; Vought, B; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50445478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50445478&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2LC 4NH8,4NH9 67495834 194943374 CHEMBL3104858 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51088203 CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32) NDAZATDQFDPQBD-UHFFFAOYSA-N 20926 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide::Isoxazole, 40f::VER-52296/NVP-AUY922 Heat shock protein 75 kDa, mitochondrial Homo sapiens 16 ChEMBL 10.1016/j.bmcl.2013.11.036 10.7270/Q2NP25WW 24332488 Ernst, JT; Liu, M; Zuccola, H; Neubert, T; Beaumont, K; Turnbull, A; Kallel, A; Vought, B; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20926&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2GJ 6LTI,2VCI,6CJS,7K9S 10096043 49689000 ZINC14974931 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51088204 CO[C@H]1C[C@H](C)Cc2c(O)c(NC(=O)C(C)=CC=C[C@@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2N=CCN(C)C InChI=1S/C32H48N4O8/c1-18-14-22-27(34-12-13-36(5)6)24(37)17-23(29(22)39)35-31(40)19(2)10-9-11-25(42-7)30(44-32(33)41)21(4)16-20(3)28(38)26(15-18)43-8/h9-12,16-18,20,25-26,28,30,37-39H,13-15H2,1-8H3,(H2,33,41)(H,35,40)/b11-9?,19-10?,21-16+,34-12?/t18-,20+,25-,26+,28-,30+/m1/s1 FVAMRTJEYDVCCB-FBEQVMAGSA-N 50445479 CHEMBL3104859 Heat shock protein 75 kDa, mitochondrial Homo sapiens 326 ChEMBL 10.1016/j.bmcl.2013.11.036 10.7270/Q2NP25WW 24332488 Ernst, JT; Liu, M; Zuccola, H; Neubert, T; Beaumont, K; Turnbull, A; Kallel, A; Vought, B; Stamos, D Vertex Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50445479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50445479&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 91898646 194943375 CHEMBL3104859 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50978838 COc1c(C)cnc(Cn2cc(C#CCC(C)(C)O)c3c(Cl)nc(N)nc23)c1C InChI=1S/C21H24ClN5O2/c1-12-9-24-15(13(2)17(12)29-5)11-27-10-14(7-6-8-21(3,4)28)16-18(22)25-20(23)26-19(16)27/h9-10,28H,8,11H2,1-5H3,(H2,23,25,26) VOASEWXFCTZRDF-UHFFFAOYSA-N 50401333 CHEMBL1230584 Heat shock protein 75 kDa, mitochondrial Homo sapiens 255 ChEMBL 10.1021/jm300810x 10.7270/Q2V125Z3 22938030 Shi, J; Van de Water, R; Hong, K; Lamer, RB; Weichert, KW; Sandoval, CM; Kasibhatla, SR; Boehm, MF; Chao, J; Lundgren, K; Timple, N; Lough, R; Ibanez, G; Boykin, C; Burrows, FJ; Kehry, MR; Yun, TJ; Harning, EK; Ambrose, C; Thompson, J; Bixler, SA; Dunah, A; Snodgrass-Belt, P; Arndt, J; Enyedy, IJ; Li, P; Hong, VS; McKenzie, A; Biamonte, MA Biogen Idec Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50401333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50401333&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 7PP 7S9I,7S9H,3NMQ 11517212 163350357 CHEMBL1230584 ZINC43132634 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075003 Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 XTWYTFMLZFPYCI-KQYNXXCUSA-N 50368125 ADENOSINE DIPHOSPHATE::ADP Heat shock protein 75 kDa, mitochondrial Homo sapiens 55594 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368125&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search ADP 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6022 160847227 16761 C03517 ZINC67267160 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075004 Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1 ZKHQWZAMYRWXGA-KQYNXXCUSA-N 50366480 ADENOSINE TRIPHOSPHATE::ATP Heat shock protein 75 kDa, mitochondrial Homo sapiens 31303 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366480&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search ATP 7UT9,1Y64,7LNU,7LN3,7LN2,7LN1,7LN0,7LN6,7LN5,7LN4,1NGE,1NGF,1NGG,1NGH,3LTA,3LTC,2NPI,2ZDQ,7NHL,1GY3,6J18,6J17,1G3I,7SGL,2BU2,2Q7G,2BUP,3H8V,6GFA,7QI6,7QI4,1H8H,4AUI,1FMW,1XDP,7ZSE,3O8L,5HNV,7ABR,3EHG,1KAZ,1KAY,1KAX,7R31,7U6Y,6TAY,6TAX,6DDZ,1XMI,1XMJ,6E0O,4A8M,4A8F,4A8Y,4A8Q,4A8S,4A8W,7JIJ,7CRC,7EKL,8H99,7N30,7N31,6YWX,6YWY,6YWE,6YW6,6YW7,6YW5,4B2Q,2W5G,2W5I,3HBT,8DAR,3CQD,4QC2,1Q97,4GY2,6FU2,1E4G,3FFK,3JZM,4CI6,1MO8,4QNR,6D3S,6D3R,7P2E,7P2Y,7V2Z,5ECQ,5ECP,4XWO,4XW5,2VHT,2VHQ,6NHX,6NHZ,6KCL,6KCM,6KC0,7JM6,7JM7,6MT9,1U5R,1I7L,1OL6,6JRS,7D4O,7D4U,7T3U,1ZAO,1Q24,6ZQM,3A5N,1PJ4,7AI5,3TPQ,7C1Z,4Q4Z,1B0U,7OQH,7LJ1,6P8J,3DGO,6ZO4,5FV0,6L59,6L57,4X6R,3R1R,7PX9,7U9X,7WTD,7WTE,7U9T,7U9K,2BBT,2BBS,2BBO,6ZTQ,4O0M,6GFH,1JKN,7NGF,7MJP,7MJQ,7MJO,1UF9,5AFU,7KSM,6UDQ,6RKE,6RKD,6RKA,7VVY,7VVZ,1KVK,4H4K,7OZ1,2OLQ,2OLR,7UUX,1NMD,1NM1,3Q60,7OIK,3BG5,3E1Y,7CGN,4GP7,1RDQ,2Q97,6ZYW,6ZYY,7W79,4DX2,3WVL,1SVM,3WV9,4DXL,6Z3R,6IUB,6IUC,5N9X,1HLU,7VLR,3JAY,6QRI,6QDV,3V2U,7AT1,7L1R,7L1S,7L1Q,6S47,6N30,7AM2,6OA9,7YFP,7YFN,7S61,7S67,7Y38,7RFH,7RFE,7RFG,6O75,6O78,1P8Z,6PTN,6PTO,7WPM,5FL7,3QUO,3QUN,4AZW,6YAR,6YAY,1G21,7EV2,7EV3,7M74,2BTF,3REP,3REU,8FHN,8FHO,7AIR,7AIQ,7AIP,3W1G,4TL7,1HCK,6HZM,7DC8,7RNR,4WTV,1AQ2,6N2Y,1NSF,1NSY,2CG9,7JGR,7JGA,5CYR,1YXQ,7FDV,7WAJ,6AB0,6AB2,6AB8,6ABK,3H5N,6YT3,6W18,6W17,6W1Z,7NZ0,7NZ3,1UEV,3T0Z,2F43,2QUI,7ZH9,8BI0,1E79,5U03,4TQD,7PO3,7RES,6CMW,2Z1U,7UJP,7UJT,7P3F,7P3N,4WAE,1TFW,1A0I,1DEJ,4M3Y,4XVU,6NOO,6NOP,6NO7,3UMP,3UMO,5J1T,8ESC,4EAJ,4EAK,4EAH,4EAG,7RAV,3G6V,6KSH,8E9B,1R9T,7MD2,6AEC,3NCQ,3MN6,3MN7,3MN5,3MN9,3UQE,3UQD,5WC0,6SYT,5WCB,4H0T,4H0V,4H0X,4H0Y,4H03,1PK8,7WYX,2FSG,7BT2,7WPT,7WPX,7WPN,7WPL,8DAV,3EQB,8CVT,4KH0,2PAV,2PAA,5EOU,5OTR,2O0H,6PAO,6PAN,6PAQ,5XVU,5FWP,5FWK,5FWL,5FWM,7CM9,7K3Z,4UP9,1TID,7Z5J,1RFQ,6ZSP,5JRJ,5LVP,5D15,6GRG,7MI6,7MI3,3SJH,2AQX,4Z94,6RJ4,3TLX,4O4F,4O4E,4O4D,7W1Y,4AN3,4KGM,4KGV,2PZE,2PZF,2PZG,3Q53,3LKI,3LKK,6PZ9,4XHO,6PZA,6PZI,7NK7,7CFI,3QO3,3QO7,7NZM,7EER,5YA1,6JD4,6JD5,5IE2,6ZXF,6ZXG,6ZXH,8DAS,8DAT,1SU2,3WQU,7QBA,5DRD,5DR2,7QO6,2R9V,4FO0,7V00,6N2Z,4FWM,1Y8R,1Y8P,1Y8Q,7KO2,7LHT,7LHW,1NYR,6BHU,6TQE,4M3T,4M3U,4M3W,4M3R,4M3X,4M3Z,2P55,1IJJ,5YZG,6JIU,6JIY,6JII,6JI0,6ZM6,6ZM5,5O5W,1F9A,8AAZ,4DLK,7QO5,7QO4,7B93,7M6L,7PW7,7M6A,7DYI,7DYE,7K2T,3C9R,1MDU,1KO5,3PGK,4AT8,4AT1,1XKV,8G8F,5XMI,5XMK,1Z0S,7VX8,7N1P,1RYR,1RYS,4FF3,6W23,6W22,6W21,6W20,6W24,4FFR,5VQA,4BJR,8DGC,4F93,6X2N,5ZTB,7R8E,7XA9,3FDX,1MIW,2Z08,2Z02,6CN2,7UIR,7P48,4KR7,3PJR,7PJI,2HMP,2HMU,2HMW,5EXY,4U07,4U0M,1WUA,7SHM,5ECK,5ECI,5ECH,5ECN,7Q6I,5LIL,7Q6F,7Q6D,3ULE,4KB6,7RGQ,6VOM,6VOL,6VOO,6VON,6VOI,6VOH,6VOK,6VOJ,6VOG,6VOF,3DKC,2GNK,3MMV,7LJF,2WPD,5V2L,5XZ9,1PHK,6O1V,7VAL,8A5P,8A5Q,1QZ5,1QZ6,3EPS,5LUH,4XBR,7PUP,7PUB,1YP3,6MAT,5X9G,5X9H,7P3W,8EOP,1LHR,1RGI,6ZR2,7WIT,3A7H,1L2T,6VTD,6VTB,7TVE,5I9E,4DQW,3CI1,3CI5,3CI4,3CIP,3CIS,6AH5,6AH4,2A84,7RZY,6RIS,6RIQ,4ZS4,2IA6,2IAJ,3ZS7,3LL3,4M9Z,4M9X,4M9Y,4M9S,7T0V,5LVO,8BX8,1MB9,2YXU,3QNO,3AB8,7ESB,2Y27,6JCU,2C01,7TCH,2C96,6Z1P,6R4S,7KL1,1ZYD,7PLJ,3M9O,4RTF,2XCW,3V01,3V04,2R86,2ILY,1N48,7W3M,7W3B,7LI3,7LI4,3Q9L,1R8B,5DK4,7U2X,2X15,5I4N,4P33,5YUD,6JH6,6JH8,6JH9,6U0M,8DGF,6IFR,2FGH,3W3D,7RL0,1ASZ,6CTA,3IQ0,4WH3,5GQL,5GQJ,8BD6,8BD4,8BD5,6TE0,4V02,4V0U,3GQK,1FQ1,6HBU,3QX9,3QXC,1U9I,5CSH,4TU0,2W00,2W02,3U8X,4ZGN,7NXV,2FF3,7K58,5T0G,5T0C,5T0J,5T0I,4GT3,7K5B,6FZB,4RQV,5ZUA,5U2H,7WIW,6RDW,7OIM,5A9P,1B8A,5A99,5A98,3X2W,3X2V,3X2U,6COM,7P5Z,7P52,7P50,2PNN,4XTR,4U1R,7ZZ3,7ZZ4,4A6X,4CBX,4CBU,4CBW,4CB0,3UC5,8FZQ,7D7Y,2RSF,6P8V,5KOY,6P80,3FPB,6EMA,2EWW,4G5Y,7ORJ,7ORK,7ORN,1B38,1B39,5Z68,5Z6R,7SXO,2PC9,7UO7,7PVN,1V1B,5L9N,3KE5,3KEU,4FXF,7NJL,7NJO,7NJN,7NJK,7NJQ,7NJS,6ZQN,5XJC,3DGL,2QKM,2QK4,2GBL,3SL2,6FML,7KZU,7KZI,5ACK,3CHW,5MWL,5MW8,5H67,5GJC,8BWY,3M3N,4HUT,7RCK,2ZHZ,7PSA,6WA8,6OIF,2OOY,4M63,7LG5,7LGQ,7LGM,6TDU,6TDY,3LMI,7JPS,7JPR,7JPQ,7JPP,7JPO,7JPN,6AWH,6AWG,4JYZ,5LXQ,6YII,6MM2,4CT2,4CT1,7T65,4CTA,6JBJ,6JBK,6JBD,3QB0,7Z3O,4IFE,3J2T,6IP2,7N74,5SVK,2A42,2A41,2A40,5OBJ,5NBN,5NBM,5NBL,1AYL,7VX0,7N6I,1KXP,1N5I,1N56,6N0T,7LJL,1V3S,7U1E,7U1S,7U1Q,2X0Q,3U9D,6AZ0,5CE3,1TQP,8APF,6JWY,6JWQ,6JWS,6JWT,6JWW,6JWV,5D4C,2XSZ,6U1D,6U1E,6U1F 5957 160845582 15422 C03517 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075005 CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3n(C)ccc3c2)c(O)cc1O InChI=1S/C20H20N4O3/c1-11(2)14-9-15(18(26)10-17(14)25)19-21-22-20(27)24(19)13-4-5-16-12(8-13)6-7-23(16)3/h4-11,25-26H,1-3H3,(H,22,27) RVAQIUULWULRNW-UHFFFAOYSA-N 50439621 GANETESPIB::STA-9090 Heat shock protein 75 kDa, mitochondrial Homo sapiens 51 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439621&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search TUH 3TUH,6LSZ 23624255 175451938 ZINC43130413 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075006 CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,30-31H,4,9-12,15H2,1-3H3,(H,27,32) NDAZATDQFDPQBD-UHFFFAOYSA-N 20926 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide::Isoxazole, 40f::VER-52296/NVP-AUY922 Heat shock protein 75 kDa, mitochondrial Homo sapiens 38 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20926&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2GJ 6LTI,2VCI,6CJS,7K9S 10096043 49689000 ZINC14974931 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075007 CC1(C)Cc2c(c(nn2-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)C(F)(F)F)C(=O)C1 InChI=1S/C23H27F3N4O3/c1-22(2)10-17-19(18(32)11-22)20(23(24,25)26)29-30(17)13-5-8-15(21(27)33)16(9-13)28-12-3-6-14(31)7-4-12/h5,8-9,12,14,28,31H,3-4,6-7,10-11H2,1-2H3,(H2,27,33)/t12-,14- ZFVRYNYOPQZKDG-MQMHXKEQSA-N 50378702 CHEMBL560895::SNX-2112 Heat shock protein 75 kDa, mitochondrial Homo sapiens 726 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378702&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 24772860 160857785 CHEMBL560895 ZINC36741071 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075008 CN(C)c1cc2OCOc2cc1Sc1nc2c(N)nccc2n1CCNCC(C)(C)C InChI=1S/C22H30N6O2S/c1-22(2,3)12-24-8-9-28-14-6-7-25-20(23)19(14)26-21(28)31-18-11-17-16(29-13-30-17)10-15(18)27(4)5/h6-7,10-11,24H,8-9,12-13H2,1-5H3,(H2,23,25) RVJIQAYFTOPTKK-UHFFFAOYSA-N 50439622 CHEMBL2419346::US10035797, Compound 111::US10428068, Compound 111::US10844056, Compound 111::US11560377, Compound 111::US9630965, Compound 111 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1586 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439622&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search EOR 6LR9 44156921 175451939 CHEMBL2419346 ZINC72315658 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075009 CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) SUPVGFZUWFMATN-UHFFFAOYSA-N 50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9 Heat shock protein 75 kDa, mitochondrial Homo sapiens 205 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180302&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search H71 2FWZ,4Z1F 9549213 104065404 CHEMBL200102 ZINC13679213 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075010 COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc23)c1C InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20) QULDDKSCVCJTPV-UHFFFAOYSA-N 20800 2-amino-6-halopurine analogue, 20::6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine::CHEMBL467399::hsp90_107 Heat shock protein 75 kDa, mitochondrial Homo sapiens 90 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20800&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 94M 7S9G,7S9F,3QDD,4Z1G,3O6O 16736529 49688874 CHEMBL467399 ZINC14974583 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075011 CO[C@H]1C[C@H](C)Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2N=CC=C InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-12,15-17,19,24-25,27,29,35-37H,1,13-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9?,18-10?,20-15+,33-12?/t17-,19+,24+,25+,27-,29+/m1/s1 VLKLQQLCVPDQFU-DHAPHRPOSA-N 15359 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate::17-(Allylamino)geldanamycin::17-AAG::17AAG::CHEMBL109480::GLD-36::Tanespimycin Heat shock protein 75 kDa, mitochondrial Homo sapiens 1496 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15359&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 91895914 46515659 64153 CHEMBL109480 ZINC49792055 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075012 CO[C@H]1CC(C)=Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2OC InChI=1S/C29H40N2O9/c1-15-11-19-25(34)20(14-21(32)27(19)39-7)31-28(35)16(2)9-8-10-22(37-5)26(40-29(30)36)18(4)13-17(3)24(33)23(12-15)38-6/h8-11,13-14,17,22-24,26,32-34H,12H2,1-7H3,(H2,30,36)(H,31,35)/b10-8?,15-11?,16-9?,18-13+/t17-,22-,23-,24+,26-/m0/s1 DKGJFBKYLFXAAJ-CBQXVVQCSA-N 20732 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate::BODIPY-labeled Geldanamycin::CHEMBL278315::GM-BODIPY::Geldanamycin::geldanomycin Heat shock protein 75 kDa, mitochondrial Homo sapiens 661 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20732&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1YET 91895934 49688806 5292 CHEMBL278315 ZINC14974435 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075023 Nc1ncnc2n(CCCNC(=S)Nc3ccc(c(c3)C(O)=O)-c3c4ccc(O)cc4oc4cc(=O)ccc34)c(Sc3cc4OCOc4cc3I)nc12 InChI=1S/C36H26IN7O7S2/c37-24-13-27-28(50-16-49-27)14-29(24)53-36-43-31-32(38)40-15-41-33(31)44(36)9-1-8-39-35(52)42-17-2-5-20(23(10-17)34(47)48)30-21-6-3-18(45)11-25(21)51-26-12-19(46)4-7-22(26)30/h2-7,10-15,45H,1,8-9,16H2,(H,47,48)(H2,38,40,41)(H2,39,42,52) WOMJYJBQSUKEIE-UHFFFAOYSA-N 50439623 CHEMBL2419342 Heat shock protein 75 kDa, mitochondrial Homo sapiens 5.9 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439623&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 73346127 175451940 CHEMBL2419342 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075024 CC(C)N(CCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12)C(=S)Nc1ccc(c(c1)C(O)=O)-c1c2ccc(O)cc2oc2cc(=O)ccc12 InChI=1S/C39H32IN7O7S2/c1-19(2)46(10-3-11-47-36-34(35(41)42-17-43-36)45-39(47)56-32-16-31-30(15-27(32)40)52-18-53-31)38(55)44-20-4-7-23(26(12-20)37(50)51)33-24-8-5-21(48)13-28(24)54-29-14-22(49)6-9-25(29)33/h4-9,12-17,19,48H,3,10-11,18H2,1-2H3,(H,44,55)(H,50,51)(H2,41,42,43) MAWBAERKPHLBIA-UHFFFAOYSA-N 50439624 CHEMBL1910764 Heat shock protein 75 kDa, mitochondrial Homo sapiens 5.8 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439624&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 57397355 175451941 CHEMBL1910764 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51075025 CO[C@H]1C[C@H](C)Cc2c(O)c(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)\C(C)=C\[C@H](C)[C@H]1O)cc(O)c2N=CCCCNC(=O)Cc1ccc2N3CCC4OC5CC[N+]6=C(C5=CC4=C3C(C)(C)c2c1)C(C)(C)c1cc(ccc61)S([O-])(=O)=O InChI=1S/C63H78N6O13S/c1-34-26-42-54(48(70)33-45(56(42)73)67-60(74)35(2)14-13-15-51(79-9)57(82-61(64)75)37(4)28-36(3)55(72)52(27-34)80-10)66-23-12-11-22-65-53(71)30-38-16-18-46-43(29-38)62(5,6)58-40-32-41-50(81-49(40)20-24-68(46)58)21-25-69-47-19-17-39(83(76,77)78)31-44(47)63(7,8)59(41)69/h13-19,23,28-29,31-34,36,49-52,55,57,72H,11-12,20-22,24-27,30H2,1-10H3,(H6-,64,65,67,70,71,73,74,75,76,77,78)/b15-13?,35-14?,37-28+,66-23?/t34-,36+,49?,50?,51+,52+,55-,57+/m1/s1 PUYUEPCBDWRZOF-BRYDXHNMSA-N 50439625 CHEMBL2419341 Heat shock protein 75 kDa, mitochondrial Homo sapiens 52 ChEMBL 10.1021/jm400619b 10.7270/Q2PN972K 23965125 Taldone, T; Patel, PD; Patel, M; Patel, HJ; Evans, CE; Rodina, A; Ochiana, S; Shah, SK; Uddin, M; Gewirth, D; Chiosis, G Memorial Sloan-Kettering Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439625&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 91898769 175451942 CHEMBL2419341 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757244 COc1c(C)cnc(Cn2cnc3c(Cl)nc(N)nc23)c1C InChI=1S/C14H15ClN6O/c1-7-4-17-9(8(2)11(7)22-3)5-21-6-18-10-12(15)19-14(16)20-13(10)21/h4,6H,5H2,1-3H3,(H2,16,19,20) QULDDKSCVCJTPV-UHFFFAOYSA-N 20800 2-amino-6-halopurine analogue, 20::6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine::CHEMBL467399::hsp90_107 Heat shock protein 75 kDa, mitochondrial Homo sapiens 535 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20800&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 94M 7S9G,7S9F,3QDD,4Z1G,3O6O 16736529 49688874 CHEMBL467399 ZINC14974583 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757253 Nc1nc(Cl)c2cnn(Cc3ccc4OCOc4c3)c2n1 InChI=1S/C13H10ClN5O2/c14-11-8-4-16-19(12(8)18-13(15)17-11)5-7-1-2-9-10(3-7)21-6-20-9/h1-4H,5-6H2,(H2,15,17,18) KIJSFKWTIJSEIJ-UHFFFAOYSA-N 50240872 CHEMBL4095912 Heat shock protein 75 kDa, mitochondrial Homo sapiens 6335 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240872&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 134480068 386401561 CHEMBL4095912 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757254 Nc1nc(Cl)c2cnn(Cc3cc4OCOc4cc3Br)c2n1 InChI=1S/C13H9BrClN5O2/c14-8-2-10-9(21-5-22-10)1-6(8)4-20-12-7(3-17-20)11(15)18-13(16)19-12/h1-3H,4-5H2,(H2,16,18,19) BIABSXPPEYWVER-UHFFFAOYSA-N 50240873 CHEMBL4068596 Heat shock protein 75 kDa, mitochondrial Homo sapiens 79 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240873&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 8MF 5Y3N 129900226 386401562 CHEMBL4068596 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757261 Nc1nc(Cl)c2cc(C(O)=O)n(Cc3ccc4OCOc4c3)c2n1 InChI=1S/C15H11ClN4O4/c16-12-8-4-9(14(21)22)20(13(8)19-15(17)18-12)5-7-1-2-10-11(3-7)24-6-23-10/h1-4H,5-6H2,(H,21,22)(H2,17,18,19) NLLIRVPVXSXWKU-UHFFFAOYSA-N 50240874 CHEMBL4079410 Heat shock protein 75 kDa, mitochondrial Homo sapiens 8434 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240874&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 137651332 386401563 CHEMBL4079410 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757262 COc1c(C)cnc(Cn2ncc3c(Cl)nc(N)nc23)c1C InChI=1S/C14H15ClN6O/c1-7-4-17-10(8(2)11(7)22-3)6-21-13-9(5-18-21)12(15)19-14(16)20-13/h4-5H,6H2,1-3H3,(H2,16,19,20) IKGRZHVFOMUXCQ-UHFFFAOYSA-N 50240875 CHEMBL4080323 Heat shock protein 75 kDa, mitochondrial Homo sapiens 138 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240875&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 8M9 5Y3O 58762794 386401564 CHEMBL4080323 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757268 CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) SUPVGFZUWFMATN-UHFFFAOYSA-N 50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9 Heat shock protein 75 kDa, mitochondrial Homo sapiens 257 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180302&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search H71 2FWZ,4Z1F 9549213 104065404 CHEMBL200102 ZINC13679213 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50757269 Nc1nc(Cl)c2cnc(Cc3ccc4OCOc4c3)n2n1 InChI=1S/C13H10ClN5O2/c14-12-8-5-16-11(19(8)18-13(15)17-12)4-7-1-2-9-10(3-7)21-6-20-9/h1-3,5H,4,6H2,(H2,15,18) JFDDMFPURVKBJR-UHFFFAOYSA-N 50240871 CHEMBL4103668 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.7b00978 10.7270/Q2J968H0 28816449 Park, HK; Jeong, H; Ko, E; Lee, G; Lee, JE; Lee, SK; Lee, AJ; Im, JY; Hu, S; Kim, SH; Lee, JH; Lee, C; Kang, S; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240871&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 137657990 386401560 CHEMBL4103668 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953195 [Br-].CCNC(=O)c1noc(c1NC(=O)CCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C39H42N3O5P/c1-4-40-39(46)37-36(38(47-42-37)32-25-31(27(2)3)33(43)26-34(32)44)41-35(45)23-15-8-16-24-48(28-17-9-5-10-18-28,29-19-11-6-12-20-29)30-21-13-7-14-22-30/h5-7,9-14,17-22,25-27H,4,8,15-16,23-24H2,1-3H3,(H3-,40,41,42,43,44,45,46)/p+1 JIBKAVNMUKPLKA-UHFFFAOYSA-O 50274518 CHEMBL4128206 Heat shock protein 75 kDa, mitochondrial Homo sapiens 25000 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274518&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 145962189 405256933 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953196 [Br-].CCNC(=O)c1noc(c1NC(=O)CCCCC[n+]1ccccc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C26H32N4O5/c1-4-27-26(34)24-23(28-22(33)11-7-5-8-12-30-13-9-6-10-14-30)25(35-29-24)19-15-18(17(2)3)20(31)16-21(19)32/h6,9-10,13-17H,4-5,7-8,11-12H2,1-3H3,(H3-,27,28,29,31,32,33,34)/p+1 KCDGYAFZTGNCQY-UHFFFAOYSA-O 50274525 CHEMBL4127843 Heat shock protein 75 kDa, mitochondrial Homo sapiens 10000 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274525&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 145962166 405256934 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953197 CCNC(=O)c1noc(c1NC(=O)CCCCC(=O)NCCCNCCNCCCN)-c1cc(C(C)C)c(O)cc1O InChI=1S/C29H47N7O6/c1-4-33-29(41)27-26(28(42-36-27)21-17-20(19(2)3)22(37)18-23(21)38)35-25(40)10-6-5-9-24(39)34-14-8-13-32-16-15-31-12-7-11-30/h17-19,31-32,37-38H,4-16,30H2,1-3H3,(H,33,41)(H,34,39)(H,35,40) LYTROOHJYURZBT-UHFFFAOYSA-N 50274533 CHEMBL4129436 Heat shock protein 75 kDa, mitochondrial Homo sapiens 5000 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274533&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 145962656 405256935 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953198 CCNC(=O)c1noc(c1NC(=O)CCCCCCc1ccc(cc1)C(=O)NC(N)=N)-c1cc(C(C)C)c(O)cc1O InChI=1S/C30H38N6O6/c1-4-33-29(41)26-25(27(42-36-26)21-15-20(17(2)3)22(37)16-23(21)38)34-24(39)10-8-6-5-7-9-18-11-13-19(14-12-18)28(40)35-30(31)32/h11-17,37-38H,4-10H2,1-3H3,(H,33,41)(H,34,39)(H4,31,32,35,40) VBNLHTYGZMIOML-UHFFFAOYSA-N 50274534 CHEMBL4128056 Heat shock protein 75 kDa, mitochondrial Homo sapiens 3000 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274534&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 146034185 405256936 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953199 CCNC(=O)c1noc(c1NC(=O)c1ccc(cc1)C(=O)NC(N)=N)-c1cc(C(C)C)c(O)cc1O InChI=1S/C24H26N6O6/c1-4-27-23(35)19-18(20(36-30-19)15-9-14(11(2)3)16(31)10-17(15)32)28-21(33)12-5-7-13(8-6-12)22(34)29-24(25)26/h5-11,31-32H,4H2,1-3H3,(H,27,35)(H,28,33)(H4,25,26,29,34) QOJWFEQFNRMAGF-UHFFFAOYSA-N 50274535 CHEMBL4126250 Heat shock protein 75 kDa, mitochondrial Homo sapiens 500 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274535&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 146034184 405256937 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953200 CCNC(=O)c1noc(c1NC(=O)CCN1CCOCC1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C22H30N4O6/c1-4-23-22(30)20-19(24-18(29)5-6-26-7-9-31-10-8-26)21(32-25-20)15-11-14(13(2)3)16(27)12-17(15)28/h11-13,27-28H,4-10H2,1-3H3,(H,23,30)(H,24,29) WURSGCMBSCSYOG-UHFFFAOYSA-N 50361701 CHEMBL1941050 Heat shock protein 75 kDa, mitochondrial Homo sapiens 20000 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361701&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 57393029 136965763 CHEMBL1941050 ZINC73223639 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953201 CCNC(=O)c1noc(c1NC(=O)c1ccc(OC)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C23H25N3O6/c1-5-24-23(30)20-19(25-22(29)13-6-8-14(31-4)9-7-13)21(32-26-20)16-10-15(12(2)3)17(27)11-18(16)28/h6-12,27-28H,5H2,1-4H3,(H,24,30)(H,25,29) BYAGRVGRUDLLDR-UHFFFAOYSA-N 50361703 CHEMBL1941052 Heat shock protein 75 kDa, mitochondrial Homo sapiens 400 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361703&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 57396510 136965765 CHEMBL1941052 ZINC73222985 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953202 COc1cccc(n1)-c1cc(F)ccc1[C@H]1Cc2nc(N)nc(C)c2C(=O)N1 InChI=1S/C20H18FN5O2/c1-10-18-16(26-20(22)23-10)9-15(25-19(18)27)12-7-6-11(21)8-13(12)14-4-3-5-17(24-14)28-2/h3-8,15H,9H2,1-2H3,(H,25,27)(H2,22,23,26)/t15-/m1/s1 WSMQUUGTQYPVPD-OAHLLOKOSA-N 50031735 CHEMBL3360305 Heat shock protein 75 kDa, mitochondrial Homo sapiens 200 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031735&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 990 4U93 46216556 103940297 CHEMBL3360305 ZINC13603344 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953203 CCNC(=O)C1=C(\C(ON1)=C1/C=C(C(C)C)C(O)=CC1=O)c1ccc(CN2CCOCC2)cc1 InChI=1S/C26H31N3O5/c1-4-27-26(32)24-23(18-7-5-17(6-8-18)15-29-9-11-33-12-10-29)25(34-28-24)20-13-19(16(2)3)21(30)14-22(20)31/h5-8,13-14,16,28,30H,4,9-12,15H2,1-3H3,(H,27,32)/b25-20- SWDZPNJZKUGIIH-QQTULTPQSA-N 50274536 CHEMBL3900791 Heat shock protein 75 kDa, mitochondrial Homo sapiens 500 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274536&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 135539077 405256938 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50953204 CCNC(=O)c1noc(c1NC(=O)c1ccc(cc1)C(=O)NC(N)=N)-c1cc(C(C)C)c(O)cc1O InChI=1S/C24H26N6O6/c1-4-27-23(35)19-18(20(36-30-19)15-9-14(11(2)3)16(31)10-17(15)32)28-21(33)12-5-7-13(8-6-12)22(34)29-24(25)26/h5-11,31-32H,4H2,1-3H3,(H,27,35)(H,28,33)(H4,25,26,29,34) QOJWFEQFNRMAGF-UHFFFAOYSA-N 50274535 CHEMBL4126250 Heat shock protein 75 kDa, mitochondrial Homo sapiens 10.0 ChEMBL 10.1016/j.bmcl.2018.05.031 10.7270/Q2028V14 29807796 Rondanin, R; Lettini, G; Oliva, P; Baruchello, R; Costantini, C; Trapella, C; Simoni, D; Bernardi, T; Sisinni, L; Pietrafesa, M; Ponterini, G; Costi, MP; Vignudelli, T; Luciani, R; Matassa, DS; Esposito, F; Landriscina, M University of Ferrara http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274535&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 146034184 405256937 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51292571 CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O InChI=1S/C25H26N8O/c1-5-16-10-17(24(26)34)6-7-20(16)33-25-22(23(30-33)15(2)3)21(8-9-27-25)32-13-19(28-14-32)18-11-29-31(4)12-18/h6-15H,5H2,1-4H3,(H2,26,34) NVVPMZUGELHVMH-UHFFFAOYSA-N 126083 US8779142, 102 Heat shock protein 75 kDa, mitochondrial Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.9b00940 10.7270/Q23X8B3C 31663736 Li, L; Wang, L; You, QD; Xu, XL China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=126083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=126083&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 67501411 225152444 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51329397 CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) SUPVGFZUWFMATN-UHFFFAOYSA-N 50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9 Heat shock protein 75 kDa, mitochondrial Homo sapiens 675 ChEMBL 10.1021/acs.jmedchem.9b01420 10.7270/Q21G0QSR 32068404 Hu, S; Ferraro, M; Thomas, AP; Chung, JM; Yoon, NG; Seol, JH; Kim, S; Kim, HU; An, MY; Ok, H; Jung, HS; Ryu, JH; Colombo, G; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180302&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search H71 2FWZ,4Z1F 9549213 104065404 CHEMBL200102 ZINC13679213 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51329398 [Br-].Nc1ncnc2n(CCCCCCCCCC[P+](c3ccccc3)(c3ccccc3)c3ccccc3)c(Sc3cc4OCOc4cc3I)nc12 InChI=1S/C40H42IN5O2PS.BrH/c41-33-26-34-35(48-29-47-34)27-36(33)50-40-45-37-38(42)43-28-44-39(37)46(40)24-16-5-3-1-2-4-6-17-25-49(30-18-10-7-11-19-30,31-20-12-8-13-21-31)32-22-14-9-15-23-32;/h7-15,18-23,26-28H,1-6,16-17,24-25,29H2,(H2,42,43,44);1H/q+1;/p-1 RZFNIEFXPGSAIC-UHFFFAOYSA-M 50538080 CHEMBL4632612 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1883 ChEMBL 10.1021/acs.jmedchem.9b01420 10.7270/Q21G0QSR 32068404 Hu, S; Ferraro, M; Thomas, AP; Chung, JM; Yoon, NG; Seol, JH; Kim, S; Kim, HU; An, MY; Ok, H; Jung, HS; Ryu, JH; Colombo, G; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50538080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50538080&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156009800 442139643 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51329399 [Br-].Nc1ncnc2n(CCCCCC[P+](c3ccccc3)(c3ccccc3)c3ccccc3)c(Sc3cc4OCOc4cc3I)nc12 InChI=1S/C36H34IN5O2PS.BrH/c37-29-22-30-31(44-25-43-30)23-32(29)46-36-41-33-34(38)39-24-40-35(33)42(36)20-12-1-2-13-21-45(26-14-6-3-7-15-26,27-16-8-4-9-17-27)28-18-10-5-11-19-28;/h3-11,14-19,22-24H,1-2,12-13,20-21,25H2,(H2,38,39,40);1H/q+1;/p-1 IGLVCZKBEMGZFY-UHFFFAOYSA-M 50538081 CHEMBL4641095 Heat shock protein 75 kDa, mitochondrial Homo sapiens 794 ChEMBL 10.1021/acs.jmedchem.9b01420 10.7270/Q21G0QSR 32068404 Hu, S; Ferraro, M; Thomas, AP; Chung, JM; Yoon, NG; Seol, JH; Kim, S; Kim, HU; An, MY; Ok, H; Jung, HS; Ryu, JH; Colombo, G; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50538081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50538081&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 154731860 442139644 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51329400 [Br-].Nc1ncnc2n(CCCCCCCC[P+](c3ccccc3)(c3ccccc3)c3ccccc3)c(Sc3cc4OCOc4cc3I)nc12 InChI=1S/C38H38IN5O2PS.BrH/c39-31-24-32-33(46-27-45-32)25-34(31)48-38-43-35-36(40)41-26-42-37(35)44(38)22-14-3-1-2-4-15-23-47(28-16-8-5-9-17-28,29-18-10-6-11-19-29)30-20-12-7-13-21-30;/h5-13,16-21,24-26H,1-4,14-15,22-23,27H2,(H2,40,41,42);1H/q+1;/p-1 RQBFRKKJVNBINT-UHFFFAOYSA-M 50538082 CHEMBL4649057 Heat shock protein 75 kDa, mitochondrial Homo sapiens 872 ChEMBL 10.1021/acs.jmedchem.9b01420 10.7270/Q21G0QSR 32068404 Hu, S; Ferraro, M; Thomas, AP; Chung, JM; Yoon, NG; Seol, JH; Kim, S; Kim, HU; An, MY; Ok, H; Jung, HS; Ryu, JH; Colombo, G; Kang, BH Ulsan National Institutes of Science and Technology (UNIST) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50538082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50538082&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156020886 442139645 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334781 CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) SUPVGFZUWFMATN-UHFFFAOYSA-N 50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9 Heat shock protein 75 kDa, mitochondrial Homo sapiens 331 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180302&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search H71 2FWZ,4Z1F 9549213 104065404 CHEMBL200102 ZINC13679213 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334782 CC(C)c1cc(-c2n[nH]c(=O)n2-c2ccc3n(C)ccc3c2)c(O)cc1O InChI=1S/C20H20N4O3/c1-11(2)14-9-15(18(26)10-17(14)25)19-21-22-20(27)24(19)13-4-5-16-12(8-13)6-7-23(16)3/h4-11,25-26H,1-3H3,(H,22,27) RVAQIUULWULRNW-UHFFFAOYSA-N 50439621 GANETESPIB::STA-9090 Heat shock protein 75 kDa, mitochondrial Homo sapiens 38 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50439621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50439621&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search TUH 3TUH,6LSZ 23624255 175451938 ZINC43130413 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334783 CC(C)c1cc(-c2nnn(Cc3ccccc3)c2-c2ccc(cc2)S(C)(=O)=O)c(O)cc1O InChI=1S/C25H25N3O4S/c1-16(2)20-13-21(23(30)14-22(20)29)24-25(18-9-11-19(12-10-18)33(3,31)32)28(27-26-24)15-17-7-5-4-6-8-17/h4-14,16,29-30H,15H2,1-3H3 GNAPCWKTAGCIKW-UHFFFAOYSA-N 50540232 CHEMBL4641526 Heat shock protein 75 kDa, mitochondrial Homo sapiens 8480 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540232&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156016513 442141795 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334784 COC(=O)Cn1nnc(c1-c1ccc(cc1)S(C)(=O)=O)-c1cc(C(C)C)c(O)cc1O InChI=1S/C21H23N3O6S/c1-12(2)15-9-16(18(26)10-17(15)25)20-21(24(23-22-20)11-19(27)30-3)13-5-7-14(8-6-13)31(4,28)29/h5-10,12,25-26H,11H2,1-4H3 JEWZURJNYGWMQD-UHFFFAOYSA-N 50540236 CHEMBL4639163 Heat shock protein 75 kDa, mitochondrial Homo sapiens 15974 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540236&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156013035 442141799 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334785 COC(=O)Cn1nnc(c1-c1cccc(c1)S(C)(=O)=O)-c1cc(C(C)C)c(O)cc1O InChI=1S/C21H23N3O6S/c1-12(2)15-9-16(18(26)10-17(15)25)20-21(24(23-22-20)11-19(27)30-3)13-6-5-7-14(8-13)31(4,28)29/h5-10,12,25-26H,11H2,1-4H3 QYOUKJDSCXNYGO-UHFFFAOYSA-N 50540237 CHEMBL4647171 Heat shock protein 75 kDa, mitochondrial Homo sapiens 17362 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540237&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156020561 442141800 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334786 COC(=O)Cn1nnc(c1-c1cccc(NS(C)(=O)=O)c1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C21H24N4O6S/c1-12(2)15-9-16(18(27)10-17(15)26)20-21(25(24-22-20)11-19(28)31-3)13-6-5-7-14(8-13)23-32(4,29)30/h5-10,12,23,26-27H,11H2,1-4H3 LABCTWVKVWHRKC-UHFFFAOYSA-N 50540238 CHEMBL4638275 Heat shock protein 75 kDa, mitochondrial Homo sapiens 24515 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540238&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156011813 442141801 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334787 COC(=O)Cn1nnc(c1-c1ccc2OCCOc2c1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C22H23N3O6/c1-12(2)14-9-15(17(27)10-16(14)26)21-22(25(24-23-21)11-20(28)29-3)13-4-5-18-19(8-13)31-7-6-30-18/h4-5,8-10,12,26-27H,6-7,11H2,1-3H3 HEPLAVLBGYNJNC-UHFFFAOYSA-N 50540239 CHEMBL4635982 Heat shock protein 75 kDa, mitochondrial Homo sapiens 11883 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540239&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156013643 442141802 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334788 COC(=O)Cn1nnc(c1-c1ccc(CN2CCCCC2)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C26H32N4O4/c1-17(2)20-13-21(23(32)14-22(20)31)25-26(30(28-27-25)16-24(33)34-3)19-9-7-18(8-10-19)15-29-11-5-4-6-12-29/h7-10,13-14,17,31-32H,4-6,11-12,15-16H2,1-3H3 BPRVTQGQMQJYBZ-UHFFFAOYSA-N 50540240 CHEMBL4647894 Heat shock protein 75 kDa, mitochondrial Homo sapiens 6983 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540240&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156020025 442141803 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334789 COC(=O)Cn1nnc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C25H30N4O5/c1-16(2)19-12-20(22(31)13-21(19)30)24-25(29(27-26-24)15-23(32)33-3)18-6-4-17(5-7-18)14-28-8-10-34-11-9-28/h4-7,12-13,16,30-31H,8-11,14-15H2,1-3H3 DCXVUQSMBOCIKC-UHFFFAOYSA-N 50540241 CHEMBL4636983 Heat shock protein 75 kDa, mitochondrial Homo sapiens 24487 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540241&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156011138 442141804 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334790 COC(=O)Cn1nnc(c1-c1ccc(OCCN(C)C)cc1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C24H30N4O5/c1-15(2)18-12-19(21(30)13-20(18)29)23-24(28(26-25-23)14-22(31)32-5)16-6-8-17(9-7-16)33-11-10-27(3)4/h6-9,12-13,15,29-30H,10-11,14H2,1-5H3 YGXDZVIEPJBYIX-UHFFFAOYSA-N 50540242 CHEMBL4648091 Heat shock protein 75 kDa, mitochondrial Homo sapiens 14147 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540242&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156020298 442141805 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334791 CCOC(=O)Cn1nnc(c1-c1ccc(cc1)S(C)(=O)=O)-c1cc(C(C)C)c(O)cc1O InChI=1S/C22H25N3O6S/c1-5-31-20(28)12-25-22(14-6-8-15(9-7-14)32(4,29)30)21(23-24-25)17-10-16(13(2)3)18(26)11-19(17)27/h6-11,13,26-27H,5,12H2,1-4H3 HWEPYGBSGLNFBC-UHFFFAOYSA-N 50540248 CHEMBL4648197 Heat shock protein 75 kDa, mitochondrial Homo sapiens 16014 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540248&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156021749 442141811 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334792 CCOC(=O)Cn1nnc(c1-c1cccc(c1)S(C)(=O)=O)-c1cc(C(C)C)c(O)cc1O InChI=1S/C22H25N3O6S/c1-5-31-20(28)12-25-22(14-7-6-8-15(9-14)32(4,29)30)21(23-24-25)17-10-16(13(2)3)18(26)11-19(17)27/h6-11,13,26-27H,5,12H2,1-4H3 XHPCPHJMLPWJID-UHFFFAOYSA-N 50540249 CHEMBL4635778 Heat shock protein 75 kDa, mitochondrial Homo sapiens 35102 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540249&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156014137 442141812 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334793 CCOC(=O)Cn1nnc(c1-c1cccc(NS(C)(=O)=O)c1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C22H26N4O6S/c1-5-32-20(29)12-26-22(14-7-6-8-15(9-14)24-33(4,30)31)21(23-25-26)17-10-16(13(2)3)18(27)11-19(17)28/h6-11,13,24,27-28H,5,12H2,1-4H3 QQYGMNMVHQBKLR-UHFFFAOYSA-N 50540250 CHEMBL4649532 Heat shock protein 75 kDa, mitochondrial Homo sapiens 33173 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540250&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156021867 442141813 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51334794 CCOC(=O)Cn1nnc(c1-c1ccc2OCCOc2c1)-c1cc(C(C)C)c(O)cc1O InChI=1S/C23H25N3O6/c1-4-30-21(29)12-26-23(14-5-6-19-20(9-14)32-8-7-31-19)22(24-25-26)16-10-15(13(2)3)17(27)11-18(16)28/h5-6,9-11,13,27-28H,4,7-8,12H2,1-3H3 AZKDPMDCFYKAOT-UHFFFAOYSA-N 50540251 CHEMBL4641450 Heat shock protein 75 kDa, mitochondrial Homo sapiens 25448 ChEMBL 10.1016/j.bmcl.2019.126809 10.7270/Q2PG1W9T 31839539 Jung, S; Yoon, NG; Yang, S; Kim, D; Lee, WS; Hong, KB; Lee, C; Kang, BH; Lee, JH; Kang, S Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540251&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 156017171 442141814 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51377903 CC1(C)Cc2c(c(nn2-c2ccc(C(N)=O)c(N[C@H]3CC[C@H](O)CC3)c2)C(F)(F)F)C(=O)C1 InChI=1S/C23H27F3N4O3/c1-22(2)10-17-19(18(32)11-22)20(23(24,25)26)29-30(17)13-5-8-15(21(27)33)16(9-13)28-12-3-6-14(31)7-4-12/h5,8-9,12,14,28,31H,3-4,6-7,10-11H2,1-2H3,(H2,27,33)/t12-,14- ZFVRYNYOPQZKDG-MQMHXKEQSA-N 50450704 CHEMBL560895::SNX-2112 Heat shock protein 75 kDa, mitochondrial Homo sapiens 791 ChEMBL 10.1021/acs.jmedchem.0c01700 10.7270/Q2125X9Q 33428418 Mishra, SJ; Liu, W; Beebe, K; Banerjee, M; Kent, CN; Munthali, V; Koren, J; Taylor, JA; Neckers, LM; Holzbeierlein, J; Blagg, BSJ The University of Notre Dame http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450704&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search E0G 6LTK,6CJR,4NH7 24772860 433920102 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51377904 Cc1cn(c2CC(C)(C)CC(=O)c12)-c1cc2CCNC(=O)c2c(c1)C1CCCC1 InChI=1S/C25H30N2O2/c1-15-14-27(20-12-25(2,3)13-21(28)22(15)20)18-10-17-8-9-26-24(29)23(17)19(11-18)16-6-4-5-7-16/h10-11,14,16H,4-9,12-13H2,1-3H3,(H,26,29) AMWZXPSBURRZMG-UHFFFAOYSA-N 50003868 CHEMBL3235353 Heat shock protein 75 kDa, mitochondrial Homo sapiens >10000 ChEMBL 10.1021/acs.jmedchem.0c01700 10.7270/Q2125X9Q 33428418 Mishra, SJ; Liu, W; Beebe, K; Banerjee, M; Kent, CN; Munthali, V; Koren, J; Taylor, JA; Neckers, LM; Holzbeierlein, J; Blagg, BSJ The University of Notre Dame http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003868&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 2QA 4O0B 73437616 242056493 CHEMBL3235353 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415784 CC(C)NCCCn1c(Sc2cc3OCOc3cc2I)nc2c(N)ncnc12 InChI=1S/C18H21IN6O2S/c1-10(2)21-4-3-5-25-17-15(16(20)22-8-23-17)24-18(25)28-14-7-13-12(6-11(14)19)26-9-27-13/h6-8,10,21H,3-5,9H2,1-2H3,(H2,20,22,23) SUPVGFZUWFMATN-UHFFFAOYSA-N 50180302 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine::8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine::8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE::CHEMBL200102::US10336757, Compound PU-H71::US10676476, Example 9 Heat shock protein 75 kDa, mitochondrial Homo sapiens 192 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180302&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search H71 2FWZ,4Z1F 9549213 104065404 CHEMBL200102 ZINC13679213 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415785 Nc1nc(Cl)c2cnn(Cc3cc4OCOc4cc3Br)c2n1 InChI=1S/C13H9BrClN5O2/c14-8-2-10-9(21-5-22-10)1-6(8)4-20-12-7(3-17-20)11(15)18-13(16)19-12/h1-3H,4-5H2,(H2,16,18,19) BIABSXPPEYWVER-UHFFFAOYSA-N 50240873 CHEMBL4068596 Heat shock protein 75 kDa, mitochondrial Homo sapiens 143 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240873&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 8MF 5Y3N 129900226 386401562 CHEMBL4068596 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415786 Nc1nc(Cl)c2nc(O)n(Cc3cc4OCOc4cc3Br)c2n1 InChI=1S/C13H9BrClN5O3/c14-6-2-8-7(22-4-23-8)1-5(6)3-20-11-9(17-13(20)21)10(15)18-12(16)19-11/h1-2H,3-4H2,(H,17,21)(H2,16,18,19) JGUUSDOBVPWHAQ-UHFFFAOYSA-N 50571896 CHEMBL4869481 Heat shock protein 75 kDa, mitochondrial Homo sapiens 66 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571896&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search FJX 7C7B 155920143 471062041 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415787 Nc1nc(Cl)c2nc(O)n(Cc3ccc(Br)cc3F)c2n1 InChI=1S/C12H8BrClFN5O/c13-6-2-1-5(7(15)3-6)4-20-10-8(17-12(20)21)9(14)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) CCUHAWKQXDIYIR-UHFFFAOYSA-N 50571897 CHEMBL4866705 Heat shock protein 75 kDa, mitochondrial Homo sapiens 58 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571897&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search FK0 7C7C 155920144 471062042 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415788 Nc1nc(Cl)c2nc(O)n(Cc3ccc(F)c(Cl)c3)c2n1 InChI=1S/C12H8Cl2FN5O/c13-6-3-5(1-2-7(6)15)4-20-10-8(17-12(20)21)9(14)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) JVLVYHXAZQKASV-UHFFFAOYSA-N 50571898 CHEMBL4870476 Heat shock protein 75 kDa, mitochondrial Homo sapiens 728 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571898&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767091 471062043 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415789 Nc1nc(Cl)c2nc(O)n(Cc3cc(Cl)ccc3F)c2n1 InChI=1S/C12H8Cl2FN5O/c13-6-1-2-7(15)5(3-6)4-20-10-8(17-12(20)21)9(14)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) RHNYJXGPWUBBAR-UHFFFAOYSA-N 50571899 CHEMBL4846028 Heat shock protein 75 kDa, mitochondrial Homo sapiens 243 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571899&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767116 471062044 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415790 Nc1nc(Cl)c2nc(O)n(Cc3cc(ccc3Cl)C(F)(F)F)c2n1 InChI=1S/C13H8Cl2F3N5O/c14-7-2-1-6(13(16,17)18)3-5(7)4-23-10-8(20-12(23)24)9(15)21-11(19)22-10/h1-3H,4H2,(H,20,24)(H2,19,21,22) OKRLTJSDZCRPOP-UHFFFAOYSA-N 50571900 CHEMBL4857569 Heat shock protein 75 kDa, mitochondrial Homo sapiens 170 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571900&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767095 471062045 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415791 Nc1nc(Cl)c2nc(O)n(Cc3ccc(Cl)c(Cl)c3)c2n1 InChI=1S/C12H8Cl3N5O/c13-6-2-1-5(3-7(6)14)4-20-10-8(17-12(20)21)9(15)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) OWOKTERNACGBKN-UHFFFAOYSA-N 50571901 CHEMBL4879021 Heat shock protein 75 kDa, mitochondrial Homo sapiens 77 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571901&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767090 471062046 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415792 COc1cc(F)c(Cn2c(O)nc3c(Cl)nc(N)nc23)c(F)c1 InChI=1S/C13H10ClF2N5O2/c1-23-5-2-7(15)6(8(16)3-5)4-21-11-9(18-13(21)22)10(14)19-12(17)20-11/h2-3H,4H2,1H3,(H,18,22)(H2,17,19,20) YAJLGUYHYSNFHG-UHFFFAOYSA-N 50571902 CHEMBL4846176 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1120 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571902&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767128 471062047 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415793 Cc1ccc(Cn2c(O)nc3c(Cl)nc(N)nc23)c(F)c1 InChI=1S/C13H11ClFN5O/c1-6-2-3-7(8(15)4-6)5-20-11-9(17-13(20)21)10(14)18-12(16)19-11/h2-4H,5H2,1H3,(H,17,21)(H2,16,18,19) HVPWZMMRXNRODN-UHFFFAOYSA-N 50571903 CHEMBL4863672 Heat shock protein 75 kDa, mitochondrial Homo sapiens 62 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571903&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767127 471062048 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415794 Nc1nc(Cl)c2nc(S)n(Cc3cc4OCOc4cc3Br)c2n1 InChI=1S/C13H9BrClN5O2S/c14-6-2-8-7(21-4-22-8)1-5(6)3-20-11-9(17-13(20)23)10(15)18-12(16)19-11/h1-2H,3-4H2,(H,17,23)(H2,16,18,19) WEPLDMSTKLFJNO-UHFFFAOYSA-N 50571904 CHEMBL4870579 Heat shock protein 75 kDa, mitochondrial Homo sapiens 738 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571904&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767133 471062049 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415795 Nc1nc(Cl)c2nc(S)n(Cc3ccc(Br)cc3F)c2n1 InChI=1S/C12H8BrClFN5S/c13-6-2-1-5(7(15)3-6)4-20-10-8(17-12(20)21)9(14)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) SRVORKWCNHDNGQ-UHFFFAOYSA-N 50571905 CHEMBL4864235 Heat shock protein 75 kDa, mitochondrial Homo sapiens 332 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571905&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767110 471062050 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415796 Nc1nc(Cl)c2nc(S)n(Cc3ccc(F)c(Cl)c3)c2n1 InChI=1S/C12H8Cl2FN5S/c13-6-3-5(1-2-7(6)15)4-20-10-8(17-12(20)21)9(14)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) GZWZOTNYXHNZOW-UHFFFAOYSA-N 50571906 CHEMBL4853048 Heat shock protein 75 kDa, mitochondrial Homo sapiens 590 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571906&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767100 471062051 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415797 Nc1nc(Cl)c2nc(S)n(Cc3cc(ccc3Cl)C(F)(F)F)c2n1 InChI=1S/C13H8Cl2F3N5S/c14-7-2-1-6(13(16,17)18)3-5(7)4-23-10-8(20-12(23)24)9(15)21-11(19)22-10/h1-3H,4H2,(H,20,24)(H2,19,21,22) RZFQHMJZZYWCKF-UHFFFAOYSA-N 50571907 CHEMBL4876733 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1220 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571907&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767121 471062052 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415798 Nc1nc(Cl)c2nc(S)n(Cc3ccc(Cl)c(Cl)c3)c2n1 InChI=1S/C12H8Cl3N5S/c13-6-2-1-5(3-7(6)14)4-20-10-8(17-12(20)21)9(15)18-11(16)19-10/h1-3H,4H2,(H,17,21)(H2,16,18,19) PQXHMWQOPLWHOH-UHFFFAOYSA-N 50571908 CHEMBL4864922 Heat shock protein 75 kDa, mitochondrial Homo sapiens 64 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571908&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767093 471062053 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415799 COc1cc(F)c(Cn2c(S)nc3c(Cl)nc(N)nc23)c(F)c1 InChI=1S/C13H10ClF2N5OS/c1-22-5-2-7(15)6(8(16)3-5)4-21-11-9(18-13(21)23)10(14)19-12(17)20-11/h2-3H,4H2,1H3,(H,18,23)(H2,17,19,20) QKSANLGUQDGCOL-UHFFFAOYSA-N 50571909 CHEMBL4860652 Heat shock protein 75 kDa, mitochondrial Homo sapiens 178 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571909&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767086 471062054 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415800 Cc1ccc(Cn2c(S)nc3c(Cl)nc(N)nc23)c(F)c1 InChI=1S/C13H11ClFN5S/c1-6-2-3-7(8(15)4-6)5-20-11-9(17-13(20)21)10(14)18-12(16)19-11/h2-4H,5H2,1H3,(H,17,21)(H2,16,18,19) QRMZJZQRVAMBCG-UHFFFAOYSA-N 50571910 CHEMBL4876871 Heat shock protein 75 kDa, mitochondrial Homo sapiens 83 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571910&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767119 471062055 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415801 Nc1nc(Cl)c2nc(S)n(Cc3c(F)ccc(F)c3F)c2n1 InChI=1S/C12H7ClF3N5S/c13-9-8-10(20-11(17)19-9)21(12(22)18-8)3-4-5(14)1-2-6(15)7(4)16/h1-2H,3H2,(H,18,22)(H2,17,19,20) DTKCWKCMUFQEST-UHFFFAOYSA-N 50571911 CHEMBL4865186 Heat shock protein 75 kDa, mitochondrial Homo sapiens 392 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571911&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767088 471062056 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415802 Nc1nc(Cl)c2nc(S)n(Cc3ccc(cc3)C(F)(F)F)c2n1 InChI=1S/C13H9ClF3N5S/c14-9-8-10(21-11(18)20-9)22(12(23)19-8)5-6-1-3-7(4-2-6)13(15,16)17/h1-4H,5H2,(H,19,23)(H2,18,20,21) MRXOKQLTKSGIKB-UHFFFAOYSA-N 50571912 CHEMBL4872173 Heat shock protein 75 kDa, mitochondrial Homo sapiens 413 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571912&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767106 471062057 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415803 Nc1nc2c(Cl)nc(N)nc2n1Cc1cc2OCOc2cc1Br InChI=1S/C13H10BrClN6O2/c14-6-2-8-7(22-4-23-8)1-5(6)3-21-11-9(18-13(21)17)10(15)19-12(16)20-11/h1-2H,3-4H2,(H2,17,18)(H2,16,19,20) FTFFKSRGYUMYQY-UHFFFAOYSA-N 50571913 CHEMBL4853988 Heat shock protein 75 kDa, mitochondrial Homo sapiens 617 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571913&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767097 471062058 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415804 Nc1nc2c(Cl)nc(N)nc2n1Cc1ccc(Br)cc1F InChI=1S/C12H9BrClFN6/c13-6-2-1-5(7(15)3-6)4-21-10-8(18-12(21)17)9(14)19-11(16)20-10/h1-3H,4H2,(H2,17,18)(H2,16,19,20) WYIGGXPFUUJVBY-UHFFFAOYSA-N 50571914 CHEMBL4859919 Heat shock protein 75 kDa, mitochondrial Homo sapiens 477 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571914&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767120 471062059 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415805 Nc1nc2c(Cl)nc(N)nc2n1Cc1ccc(F)c(Cl)c1 InChI=1S/C12H9Cl2FN6/c13-6-3-5(1-2-7(6)15)4-21-10-8(18-12(21)17)9(14)19-11(16)20-10/h1-3H,4H2,(H2,17,18)(H2,16,19,20) FKFCCMODCUOPOM-UHFFFAOYSA-N 50571915 CHEMBL4866835 Heat shock protein 75 kDa, mitochondrial Homo sapiens >5000 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571915&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767089 471062060 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415806 Nc1nc2N(Cc3cc4OCOc4cc3Br)C(=O)Cc2c(Cl)n1 InChI=1S/C14H10BrClN4O3/c15-8-3-10-9(22-5-23-10)1-6(8)4-20-11(21)2-7-12(16)18-14(17)19-13(7)20/h1,3H,2,4-5H2,(H2,17,18,19) WPXZHBZPULXOAK-UHFFFAOYSA-N 50571916 CHEMBL4870087 Heat shock protein 75 kDa, mitochondrial Homo sapiens 296 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571916&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767102 471062061 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415807 Nc1nc2N(Cc3ccc4OCOc4c3)C(=O)Cc2c(Cl)n1 InChI=1S/C14H11ClN4O3/c15-12-8-4-11(20)19(13(8)18-14(16)17-12)5-7-1-2-9-10(3-7)22-6-21-9/h1-3H,4-6H2,(H2,16,17,18) DWJMDRCODWBGEU-UHFFFAOYSA-N 50571917 CHEMBL4867384 Heat shock protein 75 kDa, mitochondrial Homo sapiens 339 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571917&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767104 471062062 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415808 Nc1nc2N(Cc3ccc(Br)cc3F)C(=O)Cc2c(Cl)n1 InChI=1S/C13H9BrClFN4O/c14-7-2-1-6(9(16)3-7)5-20-10(21)4-8-11(15)18-13(17)19-12(8)20/h1-3H,4-5H2,(H2,17,18,19) MVBWLLFRJDEVHP-UHFFFAOYSA-N 50571918 CHEMBL4871630 Heat shock protein 75 kDa, mitochondrial Homo sapiens 100 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571918&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767096 471062063 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415809 Nc1nc2N(Cc3cc(ccc3Cl)C(F)(F)F)C(=O)Cc2c(Cl)n1 InChI=1S/C14H9Cl2F3N4O/c15-9-2-1-7(14(17,18)19)3-6(9)5-23-10(24)4-8-11(16)21-13(20)22-12(8)23/h1-3H,4-5H2,(H2,20,21,22) SHDZNBAQAWUOQS-UHFFFAOYSA-N 50571919 CHEMBL4870963 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1790 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571919&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767113 471062064 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415810 COc1cccc(CN2C(=O)Cc3c2nc(N)nc3Cl)c1OC InChI=1S/C15H15ClN4O3/c1-22-10-5-3-4-8(12(10)23-2)7-20-11(21)6-9-13(16)18-15(17)19-14(9)20/h3-5H,6-7H2,1-2H3,(H2,17,18,19) IYVMQCXUYLQGHD-UHFFFAOYSA-N 50571920 CHEMBL4854861 Heat shock protein 75 kDa, mitochondrial Homo sapiens 331 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571920&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767122 471062065 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415811 Nc1nc2N(Cc3ccc(Cl)c(Cl)c3)C(=O)Cc2c(Cl)n1 InChI=1S/C13H9Cl3N4O/c14-8-2-1-6(3-9(8)15)5-20-10(21)4-7-11(16)18-13(17)19-12(7)20/h1-3H,4-5H2,(H2,17,18,19) VPULZPFYNNWXPO-UHFFFAOYSA-N 50571921 CHEMBL4866958 Heat shock protein 75 kDa, mitochondrial Homo sapiens 82 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571921&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767109 471062066 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415812 COc1ccc(F)c(CN2C(=O)Cc3c2nc(N)nc3Cl)c1F InChI=1S/C14H11ClF2N4O2/c1-23-9-3-2-8(16)7(11(9)17)5-21-10(22)4-6-12(15)19-14(18)20-13(6)21/h2-3H,4-5H2,1H3,(H2,18,19,20) GYCXQPDCHIDSOF-UHFFFAOYSA-N 50571922 CHEMBL4850126 Heat shock protein 75 kDa, mitochondrial Homo sapiens 230 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571922&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767132 471062067 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415813 Cc1ccc(CN2C(=O)Cc3c2nc(N)nc3Cl)c(F)c1 InChI=1S/C14H12ClFN4O/c1-7-2-3-8(10(16)4-7)6-20-11(21)5-9-12(15)18-14(17)19-13(9)20/h2-4H,5-6H2,1H3,(H2,17,18,19) FBDCUGDNQVNZDP-UHFFFAOYSA-N 50571923 CHEMBL4863988 Heat shock protein 75 kDa, mitochondrial Homo sapiens 90 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571923&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767131 471062068 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51415814 Nc1nc2N(Cc3ccc(cc3)C(F)(F)F)C(=O)Cc2c(Cl)n1 InChI=1S/C14H10ClF3N4O/c15-11-9-5-10(23)22(12(9)21-13(19)20-11)6-7-1-3-8(4-2-7)14(16,17)18/h1-4H,5-6H2,(H2,19,20,21) RFNSMFOUHVZBMK-UHFFFAOYSA-N 50571924 CHEMBL4874124 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1037 ChEMBL 10.1021/acsmedchemlett.1c00213 10.7270/Q2G164M9 34267888 Yang, S; Yoon, NG; Kim, D; Park, E; Kim, SY; Lee, JH; Lee, C; Kang, BH; Kang, S Ewha Womans University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571924&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 162767101 471062069 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51441618 CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1cnn(C)c1)C(N)=O InChI=1S/C25H26N8O/c1-5-16-10-17(24(26)34)6-7-20(16)33-25-22(23(30-33)15(2)3)21(8-9-27-25)32-13-19(28-14-32)18-11-29-31(4)12-18/h6-15H,5H2,1-4H3,(H2,26,34) NVVPMZUGELHVMH-UHFFFAOYSA-N 126083 US8779142, 102 Heat shock protein 75 kDa, mitochondrial Homo sapiens >50000 ChEMBL 10.1021/acs.jmedchem.0c01715 10.7270/Q2Z323H2 33621080 Yoshimura, C; Nagatoishi, S; Kuroda, D; Kodama, Y; Uno, T; Kitade, M; Chong-Takata, K; Oshiumi, H; Muraoka, H; Yamashita, S; Kawai, Y; Ohkubo, S; Tsumoto, K Taiho Pharmaceutical Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=126083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=126083&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 67501411 225152444 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51441619 CC(C)c1n[nH]c2nccc(-n3cnc(c3)-c3cccnc3)c12 InChI=1S/C17H16N6/c1-11(2)16-15-14(5-7-19-17(15)22-21-16)23-9-13(20-10-23)12-4-3-6-18-8-12/h3-11H,1-2H3,(H,19,21,22) YSZFOKSPOWYUHM-UHFFFAOYSA-N 50582397 CHEMBL5072089 Heat shock protein 75 kDa, mitochondrial Homo sapiens >300000 ChEMBL 10.1021/acs.jmedchem.0c01715 10.7270/Q2Z323H2 33621080 Yoshimura, C; Nagatoishi, S; Kuroda, D; Kodama, Y; Uno, T; Kitade, M; Chong-Takata, K; Oshiumi, H; Muraoka, H; Yamashita, S; Kawai, Y; Ohkubo, S; Tsumoto, K Taiho Pharmaceutical Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50582397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50582397&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 67502751 476027402 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51441620 CC(C)c1n[nH]c2nccc(-n3cnc(c3)-c3cnn(C)c3)c12 InChI=1S/C16H17N7/c1-10(2)15-14-13(4-5-17-16(14)21-20-15)23-8-12(18-9-23)11-6-19-22(3)7-11/h4-10H,1-3H3,(H,17,20,21) LSEUNLIDRFFKFN-UHFFFAOYSA-N 50582398 CHEMBL5087309 Heat shock protein 75 kDa, mitochondrial Homo sapiens >300000 ChEMBL 10.1021/acs.jmedchem.0c01715 10.7270/Q2Z323H2 33621080 Yoshimura, C; Nagatoishi, S; Kuroda, D; Kodama, Y; Uno, T; Kitade, M; Chong-Takata, K; Oshiumi, H; Muraoka, H; Yamashita, S; Kawai, Y; Ohkubo, S; Tsumoto, K Taiho Pharmaceutical Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50582398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50582398&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 67502393 476027403 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51441621 NC(=O)c1ccc(cc1NC1CCC(O)CC1)-c1nccc2c(ccnc12)-n1cnc(c1)-c1ccccc1 InChI=1S/C30H28N6O2/c31-30(38)23-11-6-20(16-25(23)35-21-7-9-22(37)10-8-21)28-29-24(12-14-32-28)27(13-15-33-29)36-17-26(34-18-36)19-4-2-1-3-5-19/h1-6,11-18,21-22,35,37H,7-10H2,(H2,31,38) ZWEQWORVAPXCLJ-UHFFFAOYSA-N 50582399 CHEMBL5094983 Heat shock protein 75 kDa, mitochondrial Homo sapiens >300000 ChEMBL 10.1021/acs.jmedchem.0c01715 10.7270/Q2Z323H2 33621080 Yoshimura, C; Nagatoishi, S; Kuroda, D; Kodama, Y; Uno, T; Kitade, M; Chong-Takata, K; Oshiumi, H; Muraoka, H; Yamashita, S; Kawai, Y; Ohkubo, S; Tsumoto, K Taiho Pharmaceutical Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50582399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50582399&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 166625378 476027404 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51506089 Cc1ccc(Sc2nc3c(N)ncnc3n2CCCC#C)c(C)c1 InChI=1S/C18H19N5S/c1-4-5-6-9-23-17-15(16(19)20-11-21-17)22-18(23)24-14-8-7-12(2)10-13(14)3/h1,7-8,10-11H,5-6,9H2,2-3H3,(H2,19,20,21) WLYXAWLTUOYKMO-UHFFFAOYSA-N 50165286 8-(2,4-Dimethyl-phenylsulfanyl)-9-pent-4-ynyl-9H-purin-6-ylamine::CHEMBL424824 Heat shock protein 75 kDa, mitochondrial Homo sapiens 54100 ChEMBL 10.7270/Q2TQ65N5 35691175 Yu, J; Zhang, C; Song, C Shandong University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50165286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50165286&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 11302159 104050847 CHEMBL424824 ZINC13642753 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51506097 CCc1cc(ccc1-n1nc(C(C)C)c2c(ccnc12)-n1cnc(c1)-c1ccnn1C)C(N)=O InChI=1S/C25H26N8O/c1-5-16-12-17(24(26)34)6-7-19(16)33-25-22(23(30-33)15(2)3)21(8-10-27-25)32-13-18(28-14-32)20-9-11-29-31(20)4/h6-15H,5H2,1-4H3,(H2,26,34) DXXSUFVJBBTTBM-UHFFFAOYSA-N 50606766 CHEMBL5218680 Heat shock protein 75 kDa, mitochondrial Homo sapiens >50000 ChEMBL 10.7270/Q2TQ65N5 35691175 Yu, J; Zhang, C; Song, C Shandong University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606766&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 168299502 482617617 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51516003 CC(O)(CCCc1ccccc1)c1cc(ccc1O)C(=O)N1Cc2ccccc2C1 InChI=1S/C26H27NO3/c1-26(30,15-7-10-19-8-3-2-4-9-19)23-16-20(13-14-24(23)28)25(29)27-17-21-11-5-6-12-22(21)18-27/h2-6,8-9,11-14,16,28,30H,7,10,15,17-18H2,1H3 LMAOUHXCKLNUDD-UHFFFAOYSA-N 50610079 CHEMBL5267805 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.7270/Q2JW8K3Z 36518703 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610079&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 155814161 494499827 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51516004 CC(O)(CCCc1ccc(F)cc1)c1cc(ccc1O)C(=O)N1Cc2ccccc2C1 InChI=1S/C26H26FNO3/c1-26(31,14-4-5-18-8-11-22(27)12-9-18)23-15-19(10-13-24(23)29)25(30)28-16-20-6-2-3-7-21(20)17-28/h2-3,6-13,15,29,31H,4-5,14,16-17H2,1H3 DSLAFZCEXGDWJA-UHFFFAOYSA-N 50610085 CHEMBL5288026 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.7270/Q2JW8K3Z 36518703 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610085&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 171345781 494499833 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51516005 CC(O)(CC#Cc1ccccc1)c1cc(ccc1O)C(=O)N1Cc2ccccc2C1 InChI=1S/C26H23NO3/c1-26(30,15-7-10-19-8-3-2-4-9-19)23-16-20(13-14-24(23)28)25(29)27-17-21-11-5-6-12-22(21)18-27/h2-6,8-9,11-14,16,28,30H,15,17-18H2,1H3 MHSIPJGKEHUWFL-UHFFFAOYSA-N 50610093 CHEMBL5279033 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.7270/Q2JW8K3Z 36518703 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610093&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 171352682 494499841 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51516006 CC(O)(C\C=C\c1ccccc1)c1cc(ccc1O)C(=O)N1Cc2ccccc2C1 InChI=1S/C26H25NO3/c1-26(30,15-7-10-19-8-3-2-4-9-19)23-16-20(13-14-24(23)28)25(29)27-17-21-11-5-6-12-22(21)18-27/h2-14,16,28,30H,15,17-18H2,1H3/b10-7+ VFOXVDRHVYHLKJ-JXMROGBWSA-N 50610095 CHEMBL5275106 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.7270/Q2JW8K3Z 36518703 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610095&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 171354314 494499843 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51516007 CC(C)(O)c1cc(ccc1O)C(=O)N1Cc2ccccc2C1 InChI=1S/C18H19NO3/c1-18(2,22)15-9-12(7-8-16(15)20)17(21)19-10-13-5-3-4-6-14(13)11-19/h3-9,20,22H,10-11H2,1-2H3 GVFOCRVPACSJDC-UHFFFAOYSA-N 50610096 CHEMBL5276326 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.7270/Q2JW8K3Z 36518703 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610096&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 171353254 494499844 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50989258 Nc1nc2ccc(NCc3ccc(cc3)C(=O)NC(CCC(O)=O)C(O)=O)c(Cl)c2c(=O)[nH]1 InChI=1S/C21H20ClN5O6/c22-17-13(6-5-12-16(17)19(31)27-21(23)26-12)24-9-10-1-3-11(4-2-10)18(30)25-14(20(32)33)7-8-15(28)29/h1-6,14,24H,7-9H2,(H,25,30)(H,28,29)(H,32,33)(H3,23,26,27,31) GBFUWHPCXNMVFC-UHFFFAOYSA-N 50405642 CHEMBL5272570 Heat shock protein 75 kDa, mitochondrial Homo sapiens 50000 ChEMBL 10.7270/Q20G3QBR 36507721 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405642&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 13833742 163354666 CHEMBL39851 ZINC29324107 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50989259 Nc1nc(N)c2cc(ccc2n1)N(CC=C)Cc1ccc(cc1)C(=O)NC(CCC(O)=O)C(O)=O InChI=1S/C24H26N6O5/c1-2-11-30(16-7-8-18-17(12-16)21(25)29-24(26)28-18)13-14-3-5-15(6-4-14)22(33)27-19(23(34)35)9-10-20(31)32/h2-8,12,19H,1,9-11,13H2,(H,27,33)(H,31,32)(H,34,35)(H4,25,26,28,29) OEPBAOFLMFOFDM-UHFFFAOYSA-N 50405643 CHEMBL5266569 Heat shock protein 75 kDa, mitochondrial Homo sapiens 373 ChEMBL 10.7270/Q20G3QBR 36507721 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405643&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 13989363 163354667 CHEMBL141576 ZINC27519638 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50989260 Nc1nc(Cl)c2nc(O)n(Cc3cc4OCOc4cc3Br)c2n1 InChI=1S/C13H9BrClN5O3/c14-6-2-8-7(22-4-23-8)1-5(6)3-20-11-9(17-13(20)21)10(15)18-12(16)19-11/h1-2H,3-4H2,(H,17,21)(H2,16,18,19) JGUUSDOBVPWHAQ-UHFFFAOYSA-N 50571896 CHEMBL4869481 Heat shock protein 75 kDa, mitochondrial Homo sapiens 66 ChEMBL 10.7270/Q20G3QBR 36507721 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571896&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search FJX 7C7B 155920143 471062041 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 50989262 Nc1nc(Cl)c2nc(O)n(Cc3cc4OCOc4cc3Br)c2n1 InChI=1S/C13H9BrClN5O3/c14-6-2-8-7(22-4-23-8)1-5(6)3-20-11-9(17-13(20)21)10(15)18-12(16)19-11/h1-2H,3-4H2,(H,17,21)(H2,16,18,19) JGUUSDOBVPWHAQ-UHFFFAOYSA-N 50571896 CHEMBL4869481 Heat shock protein 75 kDa, mitochondrial Homo sapiens 1600 ChEMBL 10.7270/Q20G3QBR 36507721 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50571896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50571896&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search FJX 7C7B 155920143 471062041 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 4Z1F,4Z1G,4Z1H,4Z1I,5F3K,5F5R,5HPH,5Y3N,5Y3O,7C04,7C05,7C7B,7C7C,7U8U,7U8V,7U8W,7U8X,7ULK Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51565149 CN(C)CCOc1ccc2CN(Cc2c1)C(=O)c1ccc(O)c(Sc2ccc(C)c(C)c2)c1 InChI=1S/C27H30N2O3S/c1-18-5-9-24(13-19(18)2)33-26-15-20(7-10-25(26)30)27(31)29-16-21-6-8-23(14-22(21)17-29)32-12-11-28(3)4/h5-10,13-15,30H,11-12,16-17H2,1-4H3 VRIDLWGNCJTCSL-UHFFFAOYSA-N 50629226 CHEMBL5400343 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.1021/acsmedchemlett.3c00265 10.7270/Q20G3QKW 37736193 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629226&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 7C7C,7C05,5Y3O,5Y3N,4Z1I,4Z1H,4Z1G,4Z1F,7ULK,5HPH,7U8X,7U8W,7U8V,7U8U,7C7B,7C04,5F5R,5F3K Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51565150 CN(C)CCCOc1ccc2CN(Cc2c1)C(=O)c1ccc(O)c(Sc2ccc(C)c(C)c2)c1 InChI=1S/C28H32N2O3S/c1-19-6-10-25(14-20(19)2)34-27-16-21(8-11-26(27)31)28(32)30-17-22-7-9-24(15-23(22)18-30)33-13-5-12-29(3)4/h6-11,14-16,31H,5,12-13,17-18H2,1-4H3 XWZYUOOWKPAKRU-UHFFFAOYSA-N 50629227 CHEMBL5414316 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.1021/acsmedchemlett.3c00265 10.7270/Q20G3QKW 37736193 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629227&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 7C7C,7C05,5Y3O,5Y3N,4Z1I,4Z1H,4Z1G,4Z1F,7ULK,5HPH,7U8X,7U8W,7U8V,7U8U,7C7B,7C04,5F5R,5F3K Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51565151 [O-]C(=O)C(F)(F)F.Cc1ccc(Sc2cc(ccc2O)C(=O)N2Cc3ccc(OCC[N+](C)(C)C)cc3C2)cc1C InChI=1S/C28H32N2O3S.C2HF3O2/c1-19-6-10-25(14-20(19)2)34-27-16-21(8-11-26(27)31)28(32)29-17-22-7-9-24(15-23(22)18-29)33-13-12-30(3,4)5;3-2(4,5)1(6)7/h6-11,14-16H,12-13,17-18H2,1-5H3;(H,6,7) ZANHVQHQKHZPQQ-UHFFFAOYSA-N 50629229 CHEMBL5404406 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.1021/acsmedchemlett.3c00265 10.7270/Q20G3QKW 37736193 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629229&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 7C7C,7C05,5Y3O,5Y3N,4Z1I,4Z1H,4Z1G,4Z1F,7ULK,5HPH,7U8X,7U8W,7U8V,7U8U,7C7B,7C04,5F5R,5F3K Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5 51565152 [O-]C(=O)C(F)(F)F.Cc1ccc(Sc2cc(ccc2O)C(=O)N2Cc3ccc(OCCC[N+](C)(C)C)cc3C2)cc1C InChI=1S/C29H34N2O3S.C2HF3O2/c1-20-7-11-26(15-21(20)2)35-28-17-22(9-12-27(28)32)29(33)30-18-23-8-10-25(16-24(23)19-30)34-14-6-13-31(3,4)5;3-2(4,5)1(6)7/h7-12,15-17H,6,13-14,18-19H2,1-5H3;(H,6,7) KYFFMKAIWPLJQC-UHFFFAOYSA-N 50629230 CHEMBL5399553 Heat shock protein 75 kDa, mitochondrial Homo sapiens >100000 ChEMBL 10.1021/acsmedchemlett.3c00265 10.7270/Q20G3QKW 37736193 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50629230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=50004457&target=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50629230&enzyme=Heat+shock+protein+75+kDa%2C+mitochondrial&column=ki&startPg=0&Increment=50&submit=Search 1 MARELRALLLWGRRLRPLLRAPALAAVPGGKPILCPRRTTAQLGPRRNPAWSLQAGRLFSTQTAEDKEEPLHSIISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDGQALPEMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDALQNQAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASGVRTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRRMNTLQAIWMMDPKDVREWQHEEFYRYVAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKPSMFDVSRELGSSVALYSRKVLIQTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKKDAEKYAKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRMRAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISVETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRNVLGSRVTNVKVTLRLDTHPAMVTVLEMGAARHFLRMQQLAKTQEERAQLLQPTLEINPRHALIKKLNQLRASEPGLAQLLVDQIYENAMIAAGLVDDPRAMVGRLNELLVKALERH 7C7C,7C05,5Y3O,5Y3N,4Z1I,4Z1H,4Z1G,4Z1F,7ULK,5HPH,7U8X,7U8W,7U8V,7U8U,7C7B,7C04,5F5R,5F3K Heat shock protein 75 kDa, mitochondrial TRAP1_HUMAN Q12931 B4DR68 D3DUC8 F5H897 O43642 O75235 Q9UHL5