Compile Data Set for Download or QSAR
Found 6 of ic50 for UniProtKB: Q13936
LigandPNGBDBM327851(US9663479, Formula 2 peak 2 (chiral))
Show SMILES CCC1=CC2C(C[C@]2(CN)Cc2nn[nH]n2)C1
Affinity DataIC50: 2.10nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM327848(US9663479, Formula 2 (Racemic))
Show SMILES CCC1=C[C@@H]2[C@@H](C[C@]2(CN)Cc2nn[nH]n2)C1
Affinity DataIC50: 4.20nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM327849(US9663479, Formula 3 (Racemic))
Show SMILES CCC1=C[C@@H]2[C@@H](C[C@]2(CN)Cc2nc(=O)o[nH]2)C1
Affinity DataIC50: 19nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM327847(US9663479, Pregabalin)
Show SMILES CC(C)CC(CN)CC(O)=O
Show InChI InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)
Affinity DataIC50: 23nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
LigandPNGBDBM327850(US9663479, Formula 2 peak 1 (Chiral))
Show SMILES CCC1=CC2C(C[C@@]2(CN)Cc2nn[nH]n2)C1
Affinity DataIC50: 165nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
LigandPNGBDBM327852(US9663479, Formula 1 (Racemic))
Show SMILES CCNC[C@]1(Cc2nnn[nH]2)C[C@H]2CC(CC)=C[C@@H]12
Affinity DataIC50: 500nMAssay Description:This section describes a scintillation proximity assay (SPA) to measure [3H] gabapentin ([3H]GBP) binding to membranes containing α2δ-1 and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid