Compile Data Set for Download or QSAR
maximum 50k data
Found 405 of ic50 for UniProtKB: Q9JJ16
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50081969(9-Methyl-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataIC50:  0.260nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptor from NG108-15 cells using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50060686(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinolin...)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50060685(9-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50014407(2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-qui...)
Affinity DataIC50:  0.447nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123805(5-Chloro-2-ethoxy-N-(1-ethyl-4-methyl-[1,4]diazepa...)
Affinity DataIC50:  0.550nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123797(5-Bromo-N-(1,4-diethyl-[1,4]diazepan-6-yl)-2-metho...)
Affinity DataIC50:  0.590nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123810(5-Chloro-N-(1,4-diethyl-[1,4]diazepan-6-yl)-2-meth...)
Affinity DataIC50:  0.650nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50081973(4-(4-Methyl-piperazin-1-yl)-pyrrolo[1,2-a]quinoxal...)
Affinity DataIC50:  0.670nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123811(5-Bromo-N-(1-ethyl-4-propyl-[1,4]diazepan-6-yl)-2-...)
Affinity DataIC50:  0.690nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50452955(CHEMBL36271)
Affinity DataIC50:  0.708nMAssay Description:Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123813(5-Bromo-2-methoxy-6-methylamino-N-(1-methyl-4-prop...)
Affinity DataIC50:  0.760nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50081969(9-Methyl-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataIC50:  0.790nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50060688(7-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataIC50:  0.810nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50060688(7-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50407784(CHEMBL51118)
Affinity DataIC50:  0.912nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070574(5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-...)
Affinity DataIC50:  0.970nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50407762(CHEMBL292725)
Affinity DataIC50:  1nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50081975(6-(4-Methyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1...)
Affinity DataIC50:  1nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070574(5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070571(5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50455940(CHEMBL8250)
Affinity DataIC50:  1.10nMAssay Description:Compound was evaluated for the displacement of [3H]Q-ICS-205-930 from 5-HT3 recognition sites in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50081972(9-Methyl-4-piperazin-1-yl-pyrrolo[1,2-a]quinoxalin...)
Affinity DataIC50:  1.13nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070566(5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070571(5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...)
Affinity DataIC50:  1.20nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50407789(CHEMBL52772)
Affinity DataIC50:  1.20nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070565(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50:  1.26nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070566(5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl...)
Affinity DataIC50:  1.28nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123802(5-Chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-met...)
Affinity DataIC50:  1.30nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070565(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]Q-ICS-205-930 from 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50062446(3-[3-(1-Methyl-1H-indol-3-yl)-[1,2,4]oxadiazol-5-y...)
Affinity DataIC50:  1.40nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50062446(3-[3-(1-Methyl-1H-indol-3-yl)-[1,2,4]oxadiazol-5-y...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50108392((3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-I...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of 5-HT (1 ug/mL) induced depolarization in rat vagus nerve (5-hydroxytryptamine 3 receptor antagonism)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50407786(CHEMBL54720)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123799(5-Bromo-2-ethoxy-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50:  1.48nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50366571(CHEMBL1788261)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50:  1.54nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070569(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50081989(5-(4-Methyl-piperazin-1-yl)-pyrazolo[1,5-c]quinazo...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]-zacopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070569(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Affinity DataIC50:  1.62nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]Q-ICS-205-930 from 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50069286(5-Chloro-4-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Affinity DataIC50:  1.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM85330(CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]-Q-ICS 205-930 binding to 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070573(5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Affinity DataIC50:  1.96nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070573(5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070564(5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Affinity DataIC50:  2.05nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50123816(4-Amino-N-(1-benzyl-4-methyl-[1,4]diazepan-6-yl)-5...)
Affinity DataIC50:  2.07nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine 3 receptor in rat cortical mem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50451023(MESULERGINE)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of radiolabeled [3H]-Zacopride ligand binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Universita' Degli Studi Di Salerno

Curated by ChEMBL
LigandPNGBDBM50070564(5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of [3H]- GR 65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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