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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525738(US11174252, Compound 33)
Affinity DataIC50: 2nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525743(US11174252, Compound 38)
Affinity DataIC50: 2nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525729(US11174252, Compound 24)
Affinity DataIC50: 4nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525750(US11174252, Compound 437)
Affinity DataIC50: 4nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525730(US11174252, Compound 25)
Affinity DataIC50: 5nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK9/Cyclin K (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525755(US11174252, Compound 442)
Affinity DataIC50: 41nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525749(US11174252, Compound 436)
Affinity DataIC50: 73nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525760(US11174252, Compound 447)
Affinity DataIC50: 243nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM525759(US11174252, Compound 446)
Affinity DataIC50: 280nMAssay Description:CDK9 (cyclin K): IC50 values of compounds against CDK9 (cyclin K) were determined by LanthaScreen™ Eu Kinase Binding Assay at Invitrogen Life Te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2022
Entry Details
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TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM50263013(CHEMBL4079206)
Affinity DataIC50: 412nMAssay Description:Inhibition of CDK9/cyclin K (unknown origin) after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetCyclin-K/Cyclin-dependent kinase 9(Human)
Nuvation Bio

US Patent
LigandPNGBDBM50526803(CHEMBL4434871 | US10870651, Compound 101)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds of the invention were assayed for activity against a variety of different kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2021
Entry Details
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