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Found 23 of ic50 for UniProtKB: P28335
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Affinity DataIC50:  6.10nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005836(4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl...)
Affinity DataIC50:  6.10nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM82368(CAS_121851 | CHEMBL11592 | CHEMBL301060 | NSC_1218...)
Affinity DataIC50:  10nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212607(CHEMBL57330)
Affinity DataIC50:  15nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50286670(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-naphth...)
Affinity DataIC50: >1.00E+3nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50403897(CHEMBL334923)
Affinity DataIC50:  3.16E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181840((1R,7aS)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-Meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181836(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50284689(7-Chloro-2-((E)-2-{3-[4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50284690(1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2-yl)-vinyl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50289986(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for inhibitory activity against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50033447(2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-o-toly...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested for its ability to inhibit forskolin-stimulated activity of adenylate cyclase coupled to human 5-HT 1A receptor in HeLa cells; va...More data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50005833((exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181839(CHEMBL202434 | N-exo-((4S,7alphaS)-tetrahydro-1H-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181837((1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181841((1S,7aR)-hexahydro-1H-pyrrolizin-1-ylmethyl 1H-ind...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to 5HT2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155153(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-ylmet...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50181836(4-Amino-N-(1-aza-tricyclo[3.3.1.0*3,7*]non-4-yl)-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155152(4-Amino-N-(1-aza-tricyclo[3.3.1.1*3,7*]dec-4-yl)-5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Concentration required for inhibition of 5-hydroxytryptamine 2 receptor using [3H]ketanserin as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50036868(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50212622(CHEMBL57187)
Affinity DataIC50:  1.80E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails
Target5-hydroxytryptamine receptor 2A/2B/2C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50036844(2-{4-[(5-Methoxy-chroman-3-yl)-propyl-amino]-butyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair
In DepthDetails