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Report error Found 104 of ic50 for UniProtKB: P23944
LigandPNGBDBM50029051((-)-arterenol | (-)-noradrenaline | (-)-norepineph...)
Affinity DataIC50:  16nMAssay Description:Binding affinity against Alpha adrenergic receptor using [3H]dihydroergocryptine radioligand in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50029050((-)-(R)-epinephrine | (-)-3,4-dihydroxy-alpha-((me...)
Affinity DataIC50:  17nMAssay Description:Binding affinity against Alpha adrenergic receptor using [3H]dihydroergocryptine radioligand in rat brain homogenateMore data for this Ligand-Target Pair
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataIC50:  90nMAssay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50027226(3-Methyl-1,2,3,4,4a,8-hexahydro-7-thia-3,12b-diaza...)
Affinity DataIC50:  300nMAssay Description:In vitro binding affinity towards alpha-adreno ceptor of rat forebrain using [3H]prazosinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045890(CHEMBL99069 | {2-[2-(4-Fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045891(2-[2-(4-Chloro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045881(CHEMBL98382 | N-(2-Bromo-phenyl)-2-[2-(4-fluoro-ph...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045890(CHEMBL99069 | {2-[2-(4-Fluoro-phenyl)-1H-indol-3-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045880(2-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-N,N...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045868(2-(6-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045872(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dihexyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045892(2-[5-Chloro-2-(4-fluoro-phenyl)-1H-indol-3-yl]-N,N...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045888(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N-hexyl-acet...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045896(2-[2-(4-Chloro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045854(3-(4,5-Dihydro-1H-imidazol-2-ylmethyl)-2-phenyl-1H...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045864(2-[2-(4-Chloro-phenyl)-1-methyl-1H-indol-3-yl]-N,N...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045886(3-[2-(4-Chloro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045867(CHEMBL316711 | N,N-Dibutyl-2-[2-(4-fluoro-phenyl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045865(2-(2-Phenyl-1H-indol-3-yl)-1-piperidin-1-yl-ethano...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045862(2-(2-Phenyl-1H-indol-3-yl)-1-pyrrolidin-1-yl-ethan...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045894(CHEMBL98081 | N,N-Dihexyl-2-(2-phenyl-1H-indol-3-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045879(2-[2-(4-Bromo-phenyl)-1H-indol-3-yl]-N,N-dipropyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045876(CHEMBL329499 | N-Hexyl-2-(2-phenyl-1H-indol-3-yl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045885(CHEMBL100256 | N,N-Dipropyl-2-(2-thiophen-2-yl-1H-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045857(2-(2-Phenyl-1H-indol-3-yl)-N,N-dipropyl-acetamide ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045877(2-(2-(4-fluorophenyl)-1H-indol-3-yl)-N,N-dihexylac...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045882(2-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-N,N...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045874(2-[2-(4-Iodo-phenyl)-1H-indol-3-yl]-N,N-dipropyl-a...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045860(CHEMBL327273 | N-Decyl-2-(2-phenyl-1H-indol-3-yl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045889(2-(5-Chloro-2-thiophen-2-yl-1H-indol-3-yl)-N,N-dip...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045871(2-(7-Fluoro-2-phenyl-1H-indol-3-yl)-N,N-dipropyl-a...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045873(3-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-N,N...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045878(2-(5-Chloro-2-phenyl-1H-indol-3-yl)-N,N-dihexyl-ac...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045895(2-[2-(3-Chloro-phenyl)-1H-indol-3-yl]-N,N-dipropyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045856(2-[1-(4-Bromo-benzyl)-1H-indol-3-yl]-N,N-dipropyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045870(2-(5-Methyl-2-p-tolyl-1H-indol-3-yl)-N,N-dipropyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045858(CHEMBL99509 | N,N-Diethyl-2-(2-phenyl-1H-indol-3-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045861(2-(6H-Isoindolo[2,1-a]indol-11-yl)-N,N-dipropyl-ac...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045855(2-(6,7-Dihydro-5H-benzo[3,4]azepino[1,2-a]indol-13...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045861(2-(6H-Isoindolo[2,1-a]indol-11-yl)-N,N-dipropyl-ac...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045884(CHEMBL327282 | N-Octadecyl-2-(2-phenyl-1H-indol-3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045884(CHEMBL327282 | N-Octadecyl-2-(2-phenyl-1H-indol-3-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045881(CHEMBL98382 | N-(2-Bromo-phenyl)-2-[2-(4-fluoro-ph...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045863(2-[2-(4-Fluoro-phenyl)-1H-indol-3-yl]-N,N-dipentyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045875(2-Phenyl-1,5-dihydro-3H-pyrrolo[4,3,2-de]quinolin-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [3H]WB-4101 from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50045883(CHEMBL99808 | N,N-Dihexyl-2-(6H-isoindolo[2,1-a]in...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]clonidine from alpha-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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