Compile Data Set for Download or QSAR
Found 15 of ic50 for UniProtKB: P28335
LigandPNGBDBM50224302(CHEMBL31783)
Show SMILES CSc1ccc2[nH]cc(CCN(C)C)c2c1
Show InChI InChI=1S/C13H18N2S/c1-15(2)7-6-10-9-14-13-5-4-11(16-3)8-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
LigandPNGBDBM50224301(CHEMBL417480)
Show SMILES CSc1ccc2c(CCN(C)C)c[nH]c2c1
Show InChI InChI=1S/C13H18N2S/c1-15(2)7-6-10-9-14-13-8-11(16-3)4-5-12(10)13/h4-5,8-9,14H,6-7H2,1-3H3
Affinity DataIC50: 4.07E+4nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
LigandPNGBDBM50224303(CHEMBL283686)
Show SMILES CN(C)CCc1c[nH]c2cc3OCOc3cc12
Show InChI InChI=1S/C13H16N2O2/c1-15(2)4-3-9-7-14-11-6-13-12(5-10(9)11)16-8-17-13/h5-7,14H,3-4,8H2,1-2H3
Affinity DataIC50: 4.08E+4nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
LigandPNGBDBM50224305(CHEMBL285355)
Show SMILES CSc1cccc2[nH]cc(CCN(C)C)c12
Show InChI InChI=1S/C13H18N2S/c1-15(2)8-7-10-9-14-11-5-4-6-12(16-3)13(10)11/h4-6,9,14H,7-8H2,1-3H3
Affinity DataIC50: 1.51E+5nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
LigandPNGBDBM50022536(CHEMBL15228)
Show SMILES Cl.Oc1ccc(Cc2ncc[nH]2)cc1O
Show InChI InChI=1S/C11H11N3O/c12-13-11(15)9-3-5-10(6-4-9)14-7-1-2-8-14/h1-8H,12H2,(H,13,15)
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of AA+phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
LigandPNGBDBM50224300(CHEMBL352315)
Show SMILES CC(C)N(CCc1c[nH]c2ccc3OCOc3c12)C(C)C
Show InChI InChI=1S/C17H24N2O2/c1-11(2)19(12(3)4)8-7-13-9-18-14-5-6-15-17(16(13)14)21-10-20-15/h5-6,9,11-12,18H,7-8,10H2,1-4H3
Affinity DataIC50: 2.24E+5nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
LigandPNGBDBM50022536(CHEMBL15228)
Show SMILES Cl.Oc1ccc(Cc2ncc[nH]2)cc1O
Show InChI InChI=1S/C11H11N3O/c12-13-11(15)9-3-5-10(6-4-9)14-7-1-2-8-14/h1-8H,12H2,(H,13,15)
Affinity DataIC50: 6.61E+5nMAssay Description:Inhibition of Arachidonic acid by the compound in response of SECMore data for this Ligand-Target Pair
LigandPNGBDBM50022536(CHEMBL15228)
Show SMILES Cl.Oc1ccc(Cc2ncc[nH]2)cc1O
Show InChI InChI=1S/C11H11N3O/c12-13-11(15)9-3-5-10(6-4-9)14-7-1-2-8-14/h1-8H,12H2,(H,13,15)
Affinity DataIC50: 8.13E+5nMAssay Description:Inhibition of U-46,619 + phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
LigandPNGBDBM50224304(CHEMBL368261)
Show SMILES CC(C)N(CCc1c[nH]c2cc3OCOc3cc12)C(C)C
Show InChI InChI=1S/C17H24N2O2/c1-11(2)19(12(3)4)6-5-13-9-18-15-8-17-16(7-14(13)15)20-10-21-17/h7-9,11-12,18H,5-6,10H2,1-4H3
Affinity DataIC50: 9.33E+5nMAssay Description:Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
LigandPNGBDBM50022536(CHEMBL15228)
Show SMILES Cl.Oc1ccc(Cc2ncc[nH]2)cc1O
Show InChI InChI=1S/C11H11N3O/c12-13-11(15)9-3-5-10(6-4-9)14-7-1-2-8-14/h1-8H,12H2,(H,13,15)
Affinity DataIC50: 1.55E+6nMAssay Description:Inhibition of U-46,619 by the compound in response of SECMore data for this Ligand-Target Pair
LigandPNGBDBM50022596(CHEMBL14837)
Show SMILES Cl.OC(c1ncc[nH]1)c1ccc(O)c(O)c1
Show InChI InChI=1S/C34H53N5O6/c1-22(2)16-29(40)30(41)26(17-23-12-8-6-9-13-23)37-32(43)28(19-25-20-35-21-36-25)38-31(42)27(18-24-14-10-7-11-15-24)39-33(44)45-34(3,4)5/h7,10-11,14-15,20-23,26-30,40-41H,6,8-9,12-13,16-19H2,1-5H3,(H,35,36)(H,37,43)(H,38,42)(H,39,44)/t26-,27?,28?,29?,30+/m0/s1
Affinity DataIC50: 2.29E+12nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
LigandPNGBDBM50022537(CHEMBL14508)
Show SMILES Cl.Oc1cc(F)c(CC2=NCCN2)cc1O
Show InChI InChI=1S/C11H11N3O/c12-13-11(15)9-4-3-5-10(8-9)14-6-1-2-7-14/h1-8H,12H2,(H,13,15)
Affinity DataIC50: 3.63E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
LigandPNGBDBM50022539(CHEMBL14982)
Show SMILES Cl.Oc1ccc(CC2=NCCN2)c(F)c1O
Show InChI InChI=1S/C12H13N3O/c13-14-12(16)9-10-4-3-5-11(8-10)15-6-1-2-7-15/h1-8H,9,13H2,(H,14,16)
Affinity DataIC50: 6.46E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair