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Report error Found 93 of ic50 for UniProtKB: O35433
LigandPNGBDBM50222640(CHEMBL415543)
Affinity DataIC50:  0.320nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222640(CHEMBL415543)
Affinity DataIC50:  0.320nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222695(CHEMBL155433)
Affinity DataIC50:  0.460nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222637(CHEMBL154743)
Affinity DataIC50:  0.5nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222696(CHEMBL156041)
Affinity DataIC50:  0.550nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222635(CHEMBL267205)
Affinity DataIC50:  0.720nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222647(CHEMBL154990)
Affinity DataIC50:  0.950nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222649(CHEMBL155730)
Affinity DataIC50:  0.950nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222641(CHEMBL157962)
Affinity DataIC50:  1.20nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222638(CHEMBL422702)
Affinity DataIC50:  2.40nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222644(CHEMBL434295)
Affinity DataIC50:  2.5nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222648(CHEMBL156693)
Affinity DataIC50:  3nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222639(CHEMBL356682)
Affinity DataIC50:  3.20nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222646(CHEMBL157917)
Affinity DataIC50:  5.10nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222694(CHEMBL158189)
Affinity DataIC50:  6.10nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222691(CHEMBL156927)
Affinity DataIC50:  9.30nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222690(CHEMBL345157)
Affinity DataIC50:  10nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222645(CHEMBL157918)
Affinity DataIC50:  11nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222693(CHEMBL157579)
Affinity DataIC50:  12nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224228(CHEMBL46233)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224175(CHEMBL48061)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222634(CHEMBL157473)
Affinity DataIC50: >30nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222692(CHEMBL348634)
Affinity DataIC50: >30nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222643(CHEMBL157688)
Affinity DataIC50: >30nMAssay Description:Antagonistic activity against vanilloid receptor as concentration to reduce the response to 0.5 mM capsaicin by 50% from neonatal rat culture spinal ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224176(CHEMBL296963)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20321(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Affinity DataIC50:  37nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20321(3-[(4-tert-butylphenyl)methyl]-1-[(3-fluoro-4-meth...)
Affinity DataIC50:  37nMAssay Description:Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224234(CHEMBL45252)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224229(CHEMBL48998)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224232(CHEMBL296729)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224196(CHEMBL43723)
Affinity DataIC50:  66nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224230(CHEMBL47282)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224237(CHEMBL431341)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataIC50:  110nMAssay Description:Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataIC50:  110nMAssay Description:In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20315(3-[(4-tert-butylphenyl)methyl]-1-[(4-methanesulfon...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224239(CHEMBL295773)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224100(CHEMBL44057)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224235(CHEMBL45417)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50223778(CHEMBL164875)
Affinity DataIC50:  300nMAssay Description:In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224226(CHEMBL45455)
Affinity DataIC50:  320nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224238(CHEMBL47602)
Affinity DataIC50:  350nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224195(CHEMBL48102)
Affinity DataIC50:  500nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50224194(CHEMBL47473)
Affinity DataIC50:  580nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataIC50:  590nMAssay Description:Inhibition of [Ca2+] uptake in dorsal root ganglion (DRG) neurons from neonatal Sprague-Dawley ratMore data for this Ligand-Target Pair
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataIC50:  600nMAssay Description:Ability to inhibit [Ca2+] influx neonatal rat cultured spinal sensory neurons.More data for this Ligand-Target Pair
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataIC50:  650nMAssay Description:In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.More data for this Ligand-Target Pair
LigandPNGBDBM20284(CHEMBL391997 | CPZ | Capsazepine | N-[2-(4-chlorop...)
Affinity DataIC50:  650nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
LigandPNGBDBM50224193(CHEMBL295302)
Affinity DataIC50:  770nMAssay Description:In vitro inhibitory concentration was determined against [45Ca2+]- influx in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50139640(CHEMBL165272 | N-4-Substituted-benzyl-N'-tert-buty...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro antagonist activity at the vanilloid receptor in rat DRG neurons.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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