Compile Data Set for Download or QSAR
Found 1 of ec50 for monomerid = 190028
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
vTv Therapeutics LLC

US Patent
LigandPNGBDBM190028(US9175003, 189)
Show SMILES CC[C@H](N1Cc2cc3O[C@H](COc3cc2C[C@H]1C(=O)N[C@@H](Cc1ccc(Oc2ccnc(C)c2C)cc1)C(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)c1ccccc1
Show InChI InChI=1S/C50H47Cl2N3O7/c1-4-43(34-8-6-5-7-9-34)55-27-37-26-47-46(60-29-48(62-47)35-13-17-38(18-14-35)59-28-33-12-19-40(51)41(52)22-33)25-36(37)24-44(55)49(56)54-42(50(57)58)23-32-10-15-39(16-11-32)61-45-20-21-53-31(3)30(45)2/h5-22,25-26,42-44,48H,4,23-24,27-29H2,1-3H3,(H,54,56)(H,57,58)/t42-,43-,44-,48+/m0/s1
Affinity DataEC50:  31nMAssay Description:The efficacy of GLP-1 receptor agonists was studied in a cAMP functional assay using HEK-293 Cells expressing the cloned human GLP-1 receptor. GLP-1-...More data for this Ligand-Target Pair