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Report error Found 2 of ec50 for monomerid = 301437
TargetCystic fibrosis transmembrane conductance regulator(Human)
Cystic Fibrosis Foundation Therapeutics

US Patent
LigandPNGBDBM301437(4-Amino-7-{1-[1-(2,4-difluorophenyl)-1H-pyrazol-4-...)
Affinity DataEC50:  8.94nMAssay Description:Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetCystic fibrosis transmembrane conductance regulator(Human)
Cystic Fibrosis Foundation Therapeutics

US Patent
LigandPNGBDBM301437(4-Amino-7-{1-[1-(2,4-difluorophenyl)-1H-pyrazol-4-...)
Affinity DataEC50:  30nMAssay Description:Fischer rat thyroid (FRT) cell lines stably expressing recombinant F508del V470 CFTR and halide-sensitive yellow fluorescent protein (Pedemonte et al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent