Compile Data Set for Download or QSAR
Report error Found 4 of ec50 for monomerid = 419208
TargetToll-like receptor 7(Human)
Bristol_Myers Squibb

US Patent
LigandPNGBDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  8.5nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol_Myers Squibb

US Patent
LigandPNGBDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  14.4nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Technologies clear, V-bottom 384-well plate using ECHO acoustic liquid han...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2020
Entry Details
US Patent

TargetInterleukin-6(Human)
Bristol_Myers Squibb

US Patent
LigandPNGBDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  15nMAssay Description:Compounds diluted in DMSO were transferred to individual wells of a Matrix Tech-nologies clear, V-bottom 384-well plate using ECHO acoustic liquid ha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent

TargetToll-like receptor 7(Human)
Bristol_Myers Squibb

US Patent
LigandPNGBDBM419208(US10457681, Compound Ia-03 | US10487084, Compound ...)
Affinity DataEC50:  26nMAssay Description:Engineered human embryonic kidney blue cells (HEK-Blue TLR cells; Invivogen) possessing a human TLR7-secreted embryonic alkaline phosphatase (SEAP) r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2020
Entry Details
US Patent