Compile Data Set for Download or QSAR
Report error Found 13 of ec50 for monomerid = 50085658
TargetAdenosine receptor A1(Rat)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at rat A1A adenosine receptor expressed in CHO-K1 cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 10 mins by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  8.20nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  8.20nMAssay Description:Activity at Adenosine A1 receptor of rat atriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50: >10nMAssay Description:Functional activity against adenosine A2a receptor from rat aorta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of isoproterenol-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Mouse)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  30nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to rat brain membranes by adenosine A1 receptor activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human Adenosine A1 receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphai1 after 16 hrs by beta galactosidase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Medical College of Wisconsin

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  8.20E+3nMAssay Description:Functional activity against adenosine A1 receptor from rat atria.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human Adenosine A2A receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50: >1.00E+4nMAssay Description:Functional activity at Adenosine A2A receptor as vasorelaxation of rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM50085658(2-Cl-CPA | CHEMBL284969 | 2-chloro-N6-cyclopentyla...)
Affinity DataEC50:  7.24E+4nMAssay Description:Agonist activity at human Adenosine A2B receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphas after 16 hrs by beta-galactosidase r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed