Compile Data Set for Download or QSAR
Report error Found 8 of ec50 for monomerid = 50142481
TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50:  0.0650nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at human EP4 receptor expressed in HEK293T/17 cells assessed as increase in intracellular cAMP level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rat)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at rat EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50:  56nMAssay Description:Functional activity at human EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50:  56nMAssay Description:Agonist activity against recombinant prostanoid EP4 receptor stably transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rat)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at rat EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in intracellular cAMP level incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed