Compile Data Set for Download or QSAR
Found 6 of ec50 for monomerid = 50156071
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  20nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of human mGluR5 stably expressed in CHO cells assessed as Ca2+ flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  77nMAssay Description:Activity at mGluR5 assessed as potentiation of glutamate-induced calcium flux in rat astrocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  176nMAssay Description:Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50156071(3-Cyano-N-(2,5-diphenyl-2H-pyrazol-3-yl)-benzamide...)
Affinity DataEC50:  178nMAssay Description:Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed