Affinity DataEC50: 0.000400nMAssay Description:Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.000500nMAssay Description:Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00130nMAssay Description:Agonist activity at mouse glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.00500nMAssay Description:Agonist activity at human GCGR expressed in frozen cells assessed as increase in cAMP production measured after 1 hr by HitHunter luminescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Agonist activity at mouse GCG receptor expressed in CHO cells assessed as increase in cAMP level by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0210nMAssay Description:Activation of glucagon receptor (unknown origin) transfected in HEK293 cells coinfected with luciferase reporter gene linked CRE element assessed as ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Macaca fascicularis)
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 0.0310nMAssay Description:Agonist activity at monkey GLP1R expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 0.0439nMAssay Description:Agonist activity at human GLP1R expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0440nMAssay Description:Agonist activity at mouse GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 0.0440nMAssay Description:Agonist activity at human GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 0.0570nMAssay Description:Agonist activity at human GLP1R expressed in frozen cells assessed as increase in cAMP production measured after 1 hr by HitHunter luminescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0600nMAssay Description:Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0790nMAssay Description:Agonist activity at human GCGR expressed in HEK293 cells incubated for 30 mins and assessed as increase in cAMP accumulation measured by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Agonist activity at human GCG receptor expressed in CHO cells assessed as increase in cAMP level by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.970nMAssay Description:Agonist activity at human GCGR expressed in HEK293 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Agonist activity at mouse GLP1 receptor expressed in CHO cells assessed as increase in cAMP level by TR-FRET assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 3.70nMAssay Description:Agonist activity at human GLP-1 receptor expressed in HEK293 cells assessed as cAMP accumulation after 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 3.80nMAssay Description:Agonist activity at human GLP-1R expressed in HEK293 cells incubated for 30 mins and assessed as increase in cAMP accumulation measured by HTRF assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 7.70nMAssay Description:Agonist activity at full length human GLP1R expressed in HEK293 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: 41nMAssay Description:Agonist activity at human GLP1 receptor expressed in CHO cells assessed as increase in cAMP level by TR-FRET assayMore data for this Ligand-Target Pair
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Sanofi-Aventis Deutschland
Curated by ChEMBL
Sanofi-Aventis Deutschland
Curated by ChEMBL
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GIP receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair