Compile Data Set for Download or QSAR
Report error Found 6 of ec50 for monomerid = 50272276
TargetCannabinoid receptor 2(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272276(N-(6-Chloro-1,8-naphthyridin-3-yl)-3-(3-(2-chloro-...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed