Compile Data Set for Download or QSAR
Report error Found 27 of ic50 for monomerid = 14487
TargetAdenosine receptor A3(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.10nMAssay Description:Agonist activity at human Adenosine A3 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Warwick

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 2.30nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 3.30E+3nMAssay Description:Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 2(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.70E+4nMAssay Description:Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase type 2-alpha(Human)
Smith Kline & French Research

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibitory activity (IC50) against human phosphatidylinositol 4-kinase at the ATP binding siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2019
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 3.50E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of human erythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGenome polyprotein(WNV)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Leishmania mexicanaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Tested for the inhibitory activity against Glycosomal glyceraldehyde 3-phosphate dehydrogenase (gGAPDH) of Trypanosoma bruceiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DOT1L (2 to 416 residues) (unknown origin) using biotinylated nucleosomes as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2019
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 2(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.06E+5nMAssay Description:Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetCalcium dependent protein kinase(Maize)
Tartu University

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.16E+5nMAssay Description:Inhibition of Calcium-dependent protein kinase 1 (CDPK-1) from maize seedlingsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.95E+5nMAssay Description:Inhibition of erbB-1 receptor tyrosine kinase from A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Tartu University

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 2.78E+5nMAssay Description:Inhibitory activity against Protein kinase C beta isoform (PKC) from pig spleen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetAdenylate cyclase type 5(Rat)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 3.00E+5nMAssay Description:Compound was evaluated for inhibition of adenylate cyclase from rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of recombinant METTL3/METTL14 (unknown origin) extracted from baculovirus infected Sf9 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 4.95E+5nMAssay Description:Competive inhibition of full length human METTL3/METTL14 expressed in Sf9 cells using single strand RNA 5'-AAGAACCGGACUAAGCU-3' and SAM as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of METTL3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 4.95E+5nMAssay Description:Inhibition of recombinant METTL3/METTL14 (unknown origin) expressed in baculovirus infected in Sf9 cells by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetHeat shock 70 kDa protein 1A(Human)
Vernalis (R&D)

LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.60E+5nMpH: 7.4 T: 2°CAssay Description:A fluorescein-labeled ATP-based probe was utilized, which binds to the GST fused ATPase domain (amino acids 3-383) of HSP70, producing an increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2009
Entry Details Article
PubMed
TargetPhosphoglycerate kinase 1(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 3.00E+6nMAssay Description:evaluated for the inhibition of Trypanosoma brucei Phosphoglycerate kinase (PGK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 3.50E+7nMAssay Description:Inhibition of Glyceraldehyde-3-phosphate dehydrogenase in human erythrocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.00E+7nMAssay Description:TInhibition of glyceraldehyde-3-phosphate dehydrogenase in Leishmania mexicanaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 5.00E+7nMAssay Description:Inhibitory activity measured for Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in Leishmania. mexicanaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetGlyceraldehyde-3-phosphate dehydrogenase(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of glyceraldehyde-3-phosphate dehydrogenase in Trypanosoma bruceiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMed