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Report error Found 14 of ic50 for monomerid = 24182
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  30nMAssay Description:In vitro displacement of [3H]-GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  35nMAssay Description:Inhibition of [3H]-baclofen binding to Gamma-aminobutyric acid type B receptor of cat cerebellumMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid (GABA) B receptor 1(Rat)
University of Urbino

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]-baclofen from Gamma-aminobutyric acid type B receptor in rat brain membranesMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  107nMAssay Description:Inhibition of [3H]-CGP-27,492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  200nMAssay Description:Binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptosomes after 30 minutesMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranesMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50:  420nMAssay Description:Displacement of [3H]baclofen from gamma-aminobutyric-acid B receptorMore data for this Ligand-Target Pair
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed