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Report error Found 6 of ic50 for monomerid = 405274
TargetG_PROTEIN_RECEP_F1_2 domain-containing protein(Rabbit)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 0.570nMAssay Description:Rabbit: This assay was used to determine the inhibition effect of the present compounds on the activity of rabbit GnRHr protein expressed by rabbit G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Rabbit)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 0.570nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetGonadotropin-releasing hormone II receptor(Green monkey)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 0.570nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 4.95nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
US Patent

TargetGonadotropin-releasing hormone receptor(Human)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 4.95nMAssay Description:Human: Test Example 1. Human GnRHr (GnRH Receptor) Activity Assay of the Present Compounds.In vitro GnRHr protein activity was tested by the followin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent

TargetGonadotropin releasing hormone receptor(Crab-eating macaque)
Shanghai Hengrui Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 405274BDBM405274(US10344034, Example 11 | 1-(4-(7-(2,6-difluorobenz...)
Affinity DataIC50: 78.6nMAssay Description:Monkey: This assay was used to determine the inhibition effect of the present compounds on the activity of monkey GnRHr protein expressed by monkey G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details
US Patent