Compile Data Set for Download or QSAR
Report error Found 7 of ic50 for monomerid = 50022788
TargetSugE(Salmonella newport)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Salmonella enterica serotype Newport AM17274 cephalosporinase CMY-31 by UV spectrophotometer in presence of 100 uM of cephalothinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Klebsiella pneumoniae HP205 cephalosporinase CMY-36 by UV spectrophotometer in presence of 100 uM of cephalothinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2011
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli)
Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 26nMAssay Description:Inhibition of Escherichia coli beta-lactamase ACC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 22 member 8(Mouse)
Wilkes University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2016
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 4.16E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetBile salt export pump(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022788BDBM50022788((2S,5R,6R)-6-(3-(2-chlorophenyl)-5-methylisoxazole...)
Affinity DataIC50: 3.77E+5nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed