TargetThromboxane A2 receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >0.00100nMAssay Description:In vitro binding of the compound at TP human prostaglandin receptor using [3H]-SQ-29,548 as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cellsMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro binding of the compound at FP human prostaglandin receptor using [3H]-PGF-2 alpha as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Affinity for human Prostanoid FP receptor expressed in COS-7 cellsMore data for this Ligand-Target Pair
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in ovine luteal cells (OLC)More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:In vitro binding of the compound at EP3 human prostaglandin receptor using [3H]-PGE-2 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Binding potency towards Prostaglandin F2 alpha receptor (competitive binding) with natural [3H]-PGF 2 alpha in bovine corpora lutea plasma membranes...More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:In vitro binding of the compound at EP1 human prostaglandin receptor using [3H]-PGE-2 as radioligandMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 2B1(Rattus norvegicus)
Tohoku University School Of Medicine
Curated by ChEMBL
Tohoku University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 287nMAssay Description:TP_TRANSPORTER: inhibition of PGD2 uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 322nMAssay Description:Affinity for Prostanoid EP3 receptor expressed in CHO cell lineMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Affinity for Prostanoid EP1 receptor expressed in COS-7 cells.More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Affinity for Prostanoid EP4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro binding of the compound at EP4 human prostaglandin receptor using [3H]-PGE-2 as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:In vitro binding of the compound at DP human prostaglandin receptor using [3H]- PGD-2 as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Affinity for human Prostaglandin D2 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetProstacyclin receptor(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Affinity for Prostaglandin I2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Affinity for Prostanoid EP2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetThromboxane A2 receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Procter & Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Affinity for Prostanoid TP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetProstacyclin receptor(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro binding of the compound at prostanoid IP receptor using [3H]-Iloprost as radioligandMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Procter And Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro binding of the compound at EP2 human prostaglandin receptor using [3H]-PGE-2 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair