Compile Data Set for Download or QSAR
Found 2 of ic50 for monomerid = 50050001
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050001(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Show SMILES CC(C)C[C@H](NC(=O)NC1CCCCC1C)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1
Show InChI InChI=1S/C30H42N6O4/c1-17(2)14-24(34-30(40)33-22-12-8-6-10-18(22)3)28(37)32-23(27-31-19(4)26(35-27)29(38)39)15-20-16-36(5)25-13-9-7-11-21(20)25/h7,9,11,13,16-18,22-24H,6,8,10,12,14-15H2,1-5H3,(H,31,35)(H,32,37)(H,38,39)(H2,33,34,40)/t18?,22?,23-,24+/m1/s1
Affinity DataIC50: 18nMAssay Description:Inhibitory activity was evaluated against ET- A Binding to Endothelin A receptor in MMQ cell homogenatesMore data for this Ligand-Target Pair
TargetEndothelin receptor type B(Sus scrofa)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50050001(5-Methyl-2-((R)-2-(1-methyl-1H-indol-3-yl)-1-{(S)-...)
Show SMILES CC(C)C[C@H](NC(=O)NC1CCCCC1C)C(=O)N[C@H](Cc1cn(C)c2ccccc12)c1nc(C(O)=O)c(C)[nH]1
Show InChI InChI=1S/C30H42N6O4/c1-17(2)14-24(34-30(40)33-22-12-8-6-10-18(22)3)28(37)32-23(27-31-19(4)26(35-27)29(38)39)15-20-16-36(5)25-13-9-7-11-21(20)25/h7,9,11,13,16-18,22-24H,6,8,10,12,14-15H2,1-5H3,(H,31,35)(H,32,37)(H,38,39)(H2,33,34,40)/t18?,22?,23-,24+/m1/s1
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory activity was evaluated against ET- B Binding to Endothelin B receptor from porcine cerebellar membranesMore data for this Ligand-Target Pair