Compile Data Set for Download or QSAR
Found 2 of ic50 for monomerid = 50061106
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50061106((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[isobutyl-...)
Show SMILES CCCS(=O)(=O)N(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)CC(C)C
Show InChI InChI=1S/C28H38N2O7S/c1-5-14-38(33,34)30(16-19(2)3)13-12-29-17-23(21-8-11-24-25(15-21)37-18-36-24)26(28(31)32)27(29)20-6-9-22(35-4)10-7-20/h6-11,15,19,23,26-27H,5,12-14,16-18H2,1-4H3,(H,31,32)/t23-,26-,27+/m1/s1
Affinity DataIC50: 8.10nMAssay Description:Ability to displace endothelin ([125I]-ET-1) from endothelin A receptor derived from MMQ cells of rodent.More data for this Ligand-Target Pair
TargetEndothelin receptor type B(Sus scrofa)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50061106((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-{2-[isobutyl-...)
Show SMILES CCCS(=O)(=O)N(CCN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2OCOc2c1)CC(C)C
Show InChI InChI=1S/C28H38N2O7S/c1-5-14-38(33,34)30(16-19(2)3)13-12-29-17-23(21-8-11-24-25(15-21)37-18-36-24)26(28(31)32)27(29)20-6-9-22(35-4)10-7-20/h6-11,15,19,23,26-27H,5,12-14,16-18H2,1-4H3,(H,31,32)/t23-,26-,27+/m1/s1
Affinity DataIC50: 62nMAssay Description:Ability to displace endothelin ([125I]-ET-3) from endothelin B receptor derived from cerebellar tissue of porcine.More data for this Ligand-Target Pair