Compile Data Set for Download or QSAR
Report error Found 11 of ic50 for monomerid = 50073179
TargetHistamine H1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Bridge Pharma

US Patent
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.60E+4nMAssay Description:Histamine H-4 Receptor Binding AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetHistamine H1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.60E+4nMAssay Description:Affinities of the test compounds for peripheral human histamine H-1-receptors were assessed using receptor-binding assays. The specific binding of th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2016
Entry Details
US Patent

TargetHistamine H1 receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.60E+4nMAssay Description:The specific binding of the radioactive ligand to the receptor was defined as the difference between total binding and nonspecific binding, determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2017
Entry Details
US Patent

TargetATP-dependent translocase ABCB1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 4.30E+4nMAssay Description:TP_TRANSPORTER: inhibition of Daunorubicin efflux (Daunorubicin: uM) in G185 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 6.50E+4nMAssay Description:FPT inhibitory activity was determined by the ability to inhibit the transfer of [3H]farnesyl from farnesyl pyrophosphate to H-ras-CLVSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
TargetSodium-dependent neutral amino acid transporter B(0)AT2(Human)
Max Planck Institute of Psychiatry

Curated by ChEMBL
LigandPNGBDBM50073179(CHEMBL1172 | Clarinex | Claritin-D | Claritin | SC...)
Affinity DataIC50: 1.72E+5nMAssay Description:Inhibition of eGFP-tagged human B0AT2 expressed in HEK293 cells measured within 10 mins by [3H]proline uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed