Compile Data Set for Download or QSAR
Report error Found 4 of ic50 for monomerid = 50078890
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078890(CHEMBL3416357)
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078890(CHEMBL3416357)
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078890(CHEMBL3416357)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed
TargetMacrophage-expressed gene 1 protein(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50078890(CHEMBL3416357)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2016
Entry Details Article
PubMed