Compile Data Set for Download or QSAR
Report error Found 7 of ic50 for monomerid = 50133112
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CCR2 in THP1 cells assessed as inhibition of MCP1-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 17nMAssay Description:Displacement of [125]MCP1 from CCR2 in human PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]MCP1 from human CCR2b in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against C-C chemokine receptor type 2 (antagonist activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at CCR2 in human THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 1 hr by crystal violet stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Deltagen Research Laboratories (Former Combichem)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133112BDBM50133112((R)-N-(2-(1-(2,4-dimethylbenzyl)pyrrolidin-3-ylami...)
Affinity DataIC50: 610nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed