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Report error Found 7 of ic50 for monomerid = 50305735
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]human anaphylatoxin C5a from human C5a receptor expressed in CHO cells co-expressed with Galpha16 after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human P2Y2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 6.00E+4nMAssay Description:Antagonist activity at C5a receptor in rat RAW264.7 cells assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of CXCR3 in human T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of CXCR4 in human T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed