Compile Data Set for Download or QSAR
Report error Found 7 of ic50 for monomerid = 50341056
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 5nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of AKT at S473More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341056BDBM50341056(5-(1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-1H-benz...)
Affinity DataIC50: 97nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of 4EBP1 at T37/46More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed