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Report error Found 12 of ic50 for monomerid = 50521218
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human full length P13Kdelta expressed in Sf9 cells assessed as reduction in ATP-dependent phosphorylation by chromatography...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of PI3KD (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in cytostim-induced IFNgamma production after 20 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 316nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by HT...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 398nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by HT...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 500nMAssay Description:Inhibition of human PI3K alphaMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 500nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 501nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 501nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 630nMAssay Description:Inhibition of human PI3K betaMore data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 631nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins in pre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50521218(CHEMBL4434674)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate preincubated for 15 mins followed by substrate addition measured after 60 mins by HTR...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed