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Report error Found 4 of ic50 for monomerid = 521557
TargetRous sarcoma virus integrase(RSV-Pr-C)
Janssen Biopharma

US Patent
LigandPNGBDBM521557(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50:  30nMAssay Description:Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

TargetGenome polyprotein(HRV-16)
Janssen Biopharma

US Patent
LigandPNGBDBM521557(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50:  40nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

TargetGenome polyprotein(HCV)
Janssen Biopharma

US Patent
LigandPNGBDBM521557(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50:  300nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent

TargetGenome polyprotein(DENV-1)
Janssen Biopharma

US Patent
LigandPNGBDBM521557(((2R,3S,4R,5R)-5-(4-Aminopyrrolo[2,1-f][1,2,4]tria...)
Affinity DataIC50:  1.10E+3nMAssay Description:The enzyme activity of dengue virus NS5 polymerase domain (DENVpol, serotype 2, New Guinea C strain) was measured as an incorporation of tritiated NM...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent