Compile Data Set for Download or QSAR
Found 1 of ic50 for monomerid = 548565
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Homo sapiens (Human))
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WIPO
LigandPNGBDBM548565(WO2022093881, Ex-10.74)
Show SMILES Cc1cc2cnc(NC(=O)[C@@H]3CC33CC3)cc2cc1N1CCN(CC1)[C@@]1(C)COC[C@H]1F
Show InChI InChI=1S/C25H31FN4O2/c1-16-9-18-13-27-22(28-23(31)19-12-25(19)3-4-25)11-17(18)10-20(16)29-5-7-30(8-6-29)24(2)15-32-14-21(24)26/h9-11,13,19,21H,3-8,12,14-15H2,1-2H3,(H,27,28,31)/t19-,21+,24-/m0/s1
Affinity DataIC50: 0.0800nMAssay Description: The LRRK2 kinase activity reported herein as IC50 values was determined with LanthaScreen™ technology from Life Technologies Corporation (Carlsbad, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed