Compile Data Set for Download or QSAR
Report error Found 5 of ki for monomerid = 14058
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM14058(N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...)
Affinity DataKi:  22nM ΔG°:  -43.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma

LigandPNGBDBM14058(N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...)
Affinity DataKi:  22nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Bovine)
Rh£Ne-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14058(N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...)
Affinity DataKi:  22nMAssay Description:In vitro evaluation of inhibitory activity against Coagulation factor X in prothrombinase complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2012
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Aventis Pharma

LigandPNGBDBM14058(N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...)
Affinity DataKi: >2.90E+3nM ΔG°: >-31.3kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharma

LigandPNGBDBM14058(N-[(3S)-1-[(1-aminoisoquinolin-7-yl)methyl]-2-oxop...)
Affinity DataKi: >4.00E+3nM ΔG°: >-30.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2007
Entry Details Article
PubMed