Compile Data Set for Download or QSAR
Report error Found 6 of ki for monomerid = 35665
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35665(erk000617 | pyrimidylpyrrole, 11m)
Affinity DataKi:  3nM ΔG°:  -49.5kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35665(erk000617 | pyrimidylpyrrole, 11m)
Affinity DataKi:  3nMAssay Description:Photometric_Method2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35665(erk000617 | pyrimidylpyrrole, 11m)
Affinity DataKi:  3nMAssay Description:Assay 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35665(erk000617 | pyrimidylpyrrole, 11m)
Affinity DataKi: >200nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35665(erk000617 | pyrimidylpyrrole, 11m)
Affinity DataKi: >2.50E+3nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35665(erk000617 | pyrimidylpyrrole, 11m)
Affinity DataKi: >2.50E+3nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed