Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ki for monomerid = 409014
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Eicosis

US Patent
LigandPNGBDBM409014(US10377744, Compound No. 34 | US10377744, Syn34 | ...)
Affinity DataKi:  0.370nMAssay Description:FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Eicosis

US Patent
LigandPNGBDBM409014(US10377744, Compound No. 34 | US10377744, Syn34 | ...)
Affinity DataKi:  0.370nMAssay Description:FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpoxide hydrolase 1(Homo sapiens (Human))
The Regents Of The University Of California

US Patent
LigandPNGBDBM409014(US10377744, Compound No. 34 | US10377744, Syn34 | ...)
Affinity DataKi:  0.370nMAssay Description:Scores of sEH inhibitors are known, of a variety of chemical structures. Derivatives in which the urea, carbamate or amide pharmacophore are particul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Eicosis

US Patent
LigandPNGBDBM409014(US10377744, Compound No. 34 | US10377744, Syn34 | ...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity to purified recombinant human sEH by FRET-displacement assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Eicosis

US Patent
LigandPNGBDBM409014(US10377744, Compound No. 34 | US10377744, Syn34 | ...)
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant human sEH expressed in baculovirus expression system assessed as reduction in ACPU binding incubated for 1 hr by FRET displ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Eicosis

US Patent
LigandPNGBDBM409014(US10377744, Compound No. 34 | US10377744, Syn34 | ...)
Affinity DataKi:  0.370nMAssay Description:Any of a number of standard assays for determining epoxide hydrolase activity can be used to determine inhibition of sEH. For example, suitable assay...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent