Found 11 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50014345'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.More data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in liver cell preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in HepG2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Compound was evaluated in vitro for inhibitory activity against isolated enzyme HMG-CoA reductaseMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in testes cell preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in adrenal cell preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in bovine occular cell preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for inhibitory activity against rat hepatocyteMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was evaluated for inhibitory activity against HMG-CoA reductase in spleen cell preparationMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert
Curated by ChEMBL
Warner-Lambert
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair