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Found 2 Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50406129'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50406129(CHEMBL175236)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against HMG-CoA reductase from rat liver microsomal preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
British Bio-Technology

Curated by ChEMBL
LigandPNGBDBM50406129(CHEMBL175236)
Affinity DataIC50:  29nMAssay Description:Concentration required to inhibit HMG-CoA reductase by 50% was determined in Hep G2 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed