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Found 5 Enz. Inhib. hit(s) with Target = '5'-nucleotidase' and Ligand = 'BDBM50527135'
Target5'-nucleotidase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.318nMAssay Description:Inhibition of human CD73More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.381nMAssay Description:Inhibition of recombinant human C-terminal His-tagged CD73 (27 to 549 residues) expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Rattus norvegicus (Rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.746nMAssay Description:Inhibition of recombinant rat CD73 expressed in Sf9 cells using [2,8-3H]-AMP as substrate incubated for 25 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Rattus norvegicus (Rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataKi:  0.746nMAssay Description:Inhibition of rat CD73More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
Target5'-nucleotidase(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50527135(CHEMBL4452072)
Affinity DataIC50:  3nMAssay Description:Inhibition of human C-terminal His6-tagged CD73 expressed in CHO cells preincubated for 15 mins followed by AMP addition and measured after 10 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB