Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A' and Ligand = 'BDBM50293279'
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Université de Caen

Curated by ChEMBL
LigandPNGBDBM50293279(1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...)
Show SMILES CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1
Show InChI InChI=1S/C19H25N3OS/c1-3-8-21-10-6-15(7-11-21)12-23-18-16-5-4-9-22(16)17-14(2)13-24-19(17)20-18/h4-5,9,13,15H,3,6-8,10-12H2,1-2H3
Affinity DataIC50: 6.92nMAssay Description:Displacement of [3H]granisetron from human recombinant 5HT3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Université de Caen

Curated by ChEMBL
LigandPNGBDBM50293279(1-Methyl-5-[(1-propylpiperidin-4-yl)methyloxy]-pyr...)
Show SMILES CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1
Show InChI InChI=1S/C19H25N3OS/c1-3-8-21-10-6-15(7-11-21)12-23-18-16-5-4-9-22(16)17-14(2)13-24-19(17)20-18/h4-5,9,13,15H,3,6-8,10-12H2,1-2H3
Affinity DataIC50: 385nMAssay Description:Antagonist activity at 5HT3 receptor in hybrid NG108-15 cells assessed as inhibition of 5HT-induced current by electrophysiologyMore data for this Ligand-Target Pair