Report error Found 48 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM10755'
Affinity DataEC50: 6.30nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity in the rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity as increased response to electrical stimulation in guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:In vitro relaxation of carbachol pre-contracted rat oesophageal TMM.More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Activity at SER4 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity was determined by the relaxation of the carbachol-contracted rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of radiolabeled [3H]GR-113808 ligand binding to 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 323nMAssay Description:Displacement of [3H]-GR 113808 from recombinant human brain 5HT4 receptor measured after 60 mins by radio ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 29.5nMAssay Description:Displacement of [3H]GR-113808 from human 5HT4b receptor expressed in COS7 cell membrane by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatumMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5HT4b receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 187nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:The compound was tested for their binding affinity towards 5-hydroxytryptamine 4 receptor from guinea pig striatum using [3H]GR-113808 as radioligand...More data for this Ligand-Target Pair
Affinity DataKi: 246nMAssay Description:Binding affinity to recombinant human brain 5HT4 receptor by radio ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+3nM ΔG°: -34.1kJ/mole EC50: 12nMpH: 7.4 T: 2°CAssay Description:Radioligand binding studies were performed in buffer contains test compound, [3H]-GR113808, and receptor C6 glial cell membrane preparation. Nonspeci...More data for this Ligand-Target Pair
