Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50240618'
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  3.98nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  6.31nMAssay Description:Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myenteric plexus assessed as contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataEC50:  13nMAssay Description:Induction of 5-HT4 receptor-mediated contraction in guinea pig longitudinal muscle myenteric plexusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240618BDBM50240618(CHEMBL76370 | (2E)-2-[(5-methoxy-1H-indol-3-yl)met...)
Affinity DataKi:  31nMAssay Description:Displacement of [N-methyl-3H]GR-113808 from human 5HT4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed