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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50421360'
Target5-hydroxytryptamine receptor 4(Sus scrofa)TBA
LigandPNGBDBM50421360(CHEMBL358119 | SB-207058)
Affinity DataKi:  0.0631nMAssay Description:Compound was evaluated for its ability to inhibit the binding of 5-HT4 receptor radioligand [125I]SB 207710 to piglet hippocampal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421360(CHEMBL358119 | SB-207058)
Affinity DataIC50:  0.0250nMAssay Description:Ability to antagonize 5-HT-evoked contractions mediated through 5-hydroxytryptamine 4 receptor activation in the guinea pig distal colon LMMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(GUINEA PIG)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50421360(CHEMBL358119 | SB-207058)
Affinity DataIC50:  0.0251nMAssay Description:Ability to block 5-HT4 receptor mediated effect of 5-HT was assessed in the guinea-pig distal colon longitudinal muscle myenteric plexus preparation ...More data for this Ligand-Target Pair
In DepthDetails Article