Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50458550'
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458550(CHEMBL4209274)
Affinity DataEC50:  188nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458550(CHEMBL4209274)
Affinity DataEC50:  186nMAssay Description:Agonist activity at tTA containing TCS cleavage site-fused 5-HT7 receptor (unknown origin) expressed in tTA-dependent luciferase reporter/TEV-fused b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458550(CHEMBL4209274)
Affinity DataIC50: 6.92E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458550(CHEMBL4209274)
Affinity DataIC50: 6.98E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as inhibition of Gs protein-mediated cAMP accumulation by luminescence...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458550(CHEMBL4209274)
Affinity DataKi:  104nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50458550(CHEMBL4209274)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cell membranes after 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed