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Report error Found 6 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50573236'
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Affinity DataIC50: 2.33E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Affinity DataIC50: 2.34E+3nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in cAMP accumulation incubated for 30 mins by microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Affinity DataIC50: 2.45E+4nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in beta-arrestin recruitment incubated for 22 hrs by brig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50573236(CHEMBL4854605)
Affinity DataIC50: 2.45E+4nMAssay Description:Antagonist activity at human 5-HT7 receptor expressed in HEK293 cells assessed as reduction in beta-arrestin recruitment incubated for 22 hrs by brig...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed