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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM85222'
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM85222(CAS_441351-20-8 | Lurasidone | SM 13496)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-5-CT from human 5HT7 receptor expressed in HEK293 cells incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM85222(CAS_441351-20-8 | Lurasidone | SM 13496)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-5-CT from human recombinant 5HT7b receptor measured after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Medical University Of Warsaw

Curated by ChEMBL
LigandPNGBDBM85222(CAS_441351-20-8 | Lurasidone | SM 13496)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human 5-HT7A receptor expressed in HEK cell membranes assessed as reduction in serotonin-induced cAMP accumulation incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank