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Found 5 Enz. Inhib. hit(s) with Target = '60 kDa heat shock protein, mitochondrial' and Ligand = 'BDBM50495815'
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50495815(CHEMBL3115908)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of human mitochondrial HSP60/10-mediated refolding of the denatured malate dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50495815(CHEMBL3115908)
Affinity DataIC50: >8.90E+4nMAssay Description:Inhibition of human mitochondrial HSP60/HSP10 expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50495815(CHEMBL3115908)
Affinity DataIC50:  8.90E+4nMAssay Description:Inhibition of human HSP60/HSP10 expressed in Escherichia coli Rosetta2(DE3) cells assessed as inhibition of denatured pig heart MDH refolding by meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50495815(CHEMBL3115908)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of human HSP60/HSP10 expressed in Escherichia coli Rosetta2(DE3) cells assessed as reduction in denatured pig heart MDH ATPase activity by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target60 kDa heat shock protein, mitochondrial(Homo sapiens)
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50495815(CHEMBL3115908)
Affinity DataIC50: >1.06E+5nMAssay Description:Inhibition of human mitochondrial HSP60/HSP10-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed