Report error Found 23 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM14487'
Affinity DataKd: 1.95E+3nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Nano...More data for this Ligand-Target Pair
Affinity DataEC50: 3.39E+3nMAssay Description:Effective concentration required for prolongation of the stimulus-QRS interval by 50% of the maximum response at the A1 adenosine receptor in langend...More data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Agonist activity at human recombinant adenosine A1 receptor by cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Agonist activity at human adenosine A1 receptor transfected in CHO cells assessed as changes in cAMP formation in the presence of nitrobenzylthioinos...More data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+3nMAssay Description:Agonist activity at human Adenosine A1 receptor expressed in yeast cells coexpressed with chimeric GPA1/Galphai1 after 16 hrs by beta galactosidase r...More data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKd: 295nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells assessed as kinetic dissociation constant by Na...More data for this Ligand-Target Pair
Affinity DataEC50: 3.39E+3nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for...More data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Agonist activity at human adenosine A1 receptor expressed in CHO cells assessed as increase of intracellular calcium levelMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of isoproterenol-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.41E+3nMAssay Description:Agonist activity at human A1AR assessed as induction of Ca2+ ion mobilization by orthogonal functional assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Agonist activity at human Adenosine A1 receptor transfected in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 m...More data for this Ligand-Target Pair
Affinity DataKi: 5.10nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]R-PIA from rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Evaluated for the binding affinity towards the Adenosine A1 receptor in corpora striata of rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of binding of [3H]N6-cyclohexyladenosine to adenosine A1 receptor of rat whole brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Affinity for Adenosine A1 receptor determined by [3H]N6-cyclohexyladenosine binding to rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 813nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused human adenosine A1 receptor expressed in HEK293 cells measured for 10 mins by NanoBRET competition bi...More data for this Ligand-Target Pair
Affinity DataKi: 871nMAssay Description:Inhibition of CA200645 binding to NanoLuc-fused rat adenosine A1 receptor expressed in HEK293 cells measured for 10 mins by NanoBRET competition bind...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nMAssay Description:Binding affinity to adenosine A1 receptor in rat brain membranes by measuring displacement of specific [3H]PIA as radioligand.More data for this Ligand-Target Pair
