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Found 2 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member C4' and Ligand = 'BDBM50427622'
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50427622(CHEMBL2323508 | US9346803, Table 2, Compound 10: 3...)
Affinity DataIC50:  1.95nMAssay Description:Inhibitors were initially screened for an ability to block the NADP+ dependent oxidation of the artificial substrate S-tetralol catalyzed by AKR1C3. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50427622(CHEMBL2323508 | US9346803, Table 2, Compound 10: 3...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of human recombinant AKR1C4-mediated NADP+-dependent oxidation of S-(+)-1,2,3,4-tetrahydro-1-naphtholMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed