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Found 4 Enz. Inhib. hit(s) with Target = 'Apelin receptor' and Ligand = 'BDBM422376'
TargetApelin receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422376(5-(4- cyclopropylbenzene- sulfonyl)-1-(2,6- dimeth...)
Affinity DataEC50:  5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Mus musculus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM422376(5-(4- cyclopropylbenzene- sulfonyl)-1-(2,6- dimeth...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApelin receptor(Rattus norvegicus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM422376(5-(4- cyclopropylbenzene- sulfonyl)-1-(2,6- dimeth...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM422376(5-(4- cyclopropylbenzene- sulfonyl)-1-(2,6- dimeth...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed